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Kaouther</title> <meta name="description" content="Search results for: Ahmed Mbarek Kaouther"> <meta name="keywords" content="Ahmed Mbarek Kaouther"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Ahmed Mbarek Kaouther"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1604</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Ahmed Mbarek Kaouther</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1454</span> An Approach towards Intelligent Urbanism in New Communities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sherine%20Shafik%20Aly">Sherine Shafik Aly</a>, <a href="https://publications.waset.org/abstracts/search?q=Farida%20Ahmed%20El%20Mallah"> Farida Ahmed El Mallah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Technology is a quoted keyword nowadays in all fields; it has been recently thought of and integrated into urban development. This research explains the role of technology in establishing intelligent urbanism to create a convivial and sustainable environment for people to live in. Cities are downgrading socially, economically and environmentally. A framework is to be developed where these three pillars are involved in the planning, design, and spreading of technology to create convivial environments. The aim of this research is achieved by highlighting the importance and approaches of intelligent urbanism, it’s characteristics and principles, then analyzing some relevant examples to achieve a set of guidelines. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=convivial" title="convivial">convivial</a>, <a href="https://publications.waset.org/abstracts/search?q=intelligent" title=" intelligent"> intelligent</a>, <a href="https://publications.waset.org/abstracts/search?q=technology" title=" technology"> technology</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20development" title=" urban development"> urban development</a> </p> <a href="https://publications.waset.org/abstracts/79697/an-approach-towards-intelligent-urbanism-in-new-communities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79697.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">260</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1453</span> The K-Distance Neighborhood Polynomial of a Graph</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Soner%20Nandappa%20D.">Soner Nandappa D.</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mohammed%20Naji"> Ahmed Mohammed Naji</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In a graph G = (V, E), the distance from a vertex v to a vertex u is the length of shortest v to u path. The eccentricity e(v) of v is the distance to a farthest vertex from v. The diameter diam(G) is the maximum eccentricity. The k-distance neighborhood of v, for 0 ≤ k ≤ e(v), is Nk(v) = {u ϵ V (G) : d(v, u) = k}. In this paper, we introduce a new distance degree based topological polynomial of a graph G is called a k- distance neighborhood polynomial, denoted Nk(G, x). It is a polynomial with the coefficient of the term k, for 0 ≤ k ≤ e(v), is the sum of the cardinalities of Nk(v) for every v ϵ V (G). Some properties of k- distance neighborhood polynomials are obtained. Exact formulas of the k- distance neighborhood polynomial for some well-known graphs, Cartesian product and join of graphs are presented. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vertex%20degrees" title="vertex degrees">vertex degrees</a>, <a href="https://publications.waset.org/abstracts/search?q=distance%20in%20graphs" title=" distance in graphs"> distance in graphs</a>, <a href="https://publications.waset.org/abstracts/search?q=graph%20operation" title=" graph operation"> graph operation</a>, <a href="https://publications.waset.org/abstracts/search?q=Nk-polynomials" title=" Nk-polynomials"> Nk-polynomials</a> </p> <a href="https://publications.waset.org/abstracts/52946/the-k-distance-neighborhood-polynomial-of-a-graph" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52946.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">549</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1452</span> A Variant of a Double Structure-Preserving QR Algorithm for Symmetric and Hamiltonian Matrices</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Salam">Ahmed Salam</a>, <a href="https://publications.waset.org/abstracts/search?q=Haithem%20Benkahla"> Haithem Benkahla</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Recently, an efficient backward-stable algorithm for computing eigenvalues and vectors of a symmetric and Hamiltonian matrix has been proposed. The method preserves the symmetric and Hamiltonian structures of the original matrix, during the whole process. In this paper, we revisit the method. We derive a way for implementing the reduction of the matrix to the appropriate condensed form. Then, we construct a novel version of the implicit QR-algorithm for computing the eigenvalues and vectors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=block%20implicit%20QR%20algorithm" title="block implicit QR algorithm">block implicit QR algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=preservation%20of%20a%20double%20structure" title=" preservation of a double structure"> preservation of a double structure</a>, <a href="https://publications.waset.org/abstracts/search?q=QR%20algorithm" title=" QR algorithm"> QR algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=symmetric%20and%20Hamiltonian%20structures" title=" symmetric and Hamiltonian structures"> symmetric and Hamiltonian structures</a> </p> <a href="https://publications.waset.org/abstracts/61018/a-variant-of-a-double-structure-preserving-qr-algorithm-for-symmetric-and-hamiltonian-matrices" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61018.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">409</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1451</span> Evaluation of Hydrocarbons in Tissues of Bivalve Mollusks from the Red Sea Coast</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Asma%20Ahmed%20Aljohani">Asma Ahmed Aljohani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Orif"> Mohammed Orif</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The concentration of polycyclic aromatic hydrocarbons (PAH) in clam (A. glabrata) was examined in samples collected from Alseef Beach, 30 km south of Jeddah city. Gas chromatography-mass spectrometry (GC-MS) was used to analyse the 14 PAHs. The concentration of total PAHs was found to range from 11.521 to 40.149 ng/gdw with a mean concentration of 21.857 ng/gdw, which is lower compared to similar studies. The lower molecular weight PAHs with three rings comprised 18.14% of the total PAH concentrations in the clams, while the high molecular weight PAHs with four rings, five rings, and six rings account for 81.86%. Diagnostic ratios for PAH source distinction suggested pyrogenic or anthropogenic sources. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bivalves" title="bivalves">bivalves</a>, <a href="https://publications.waset.org/abstracts/search?q=biomonitoring" title=" biomonitoring"> biomonitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrocarbons" title=" hydrocarbons"> hydrocarbons</a>, <a href="https://publications.waset.org/abstracts/search?q=PAHs" title=" PAHs"> PAHs</a> </p> <a href="https://publications.waset.org/abstracts/159285/evaluation-of-hydrocarbons-in-tissues-of-bivalve-mollusks-from-the-red-sea-coast" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159285.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">98</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1450</span> A Two-Step Framework for Unsupervised Speaker Segmentation Using BIC and Artificial Neural Network</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Alwosheel">Ahmad Alwosheel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Alqaraawi"> Ahmed Alqaraawi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work proposes a new speaker segmentation approach for two speakers. It is an online approach that does not require a prior information about speaker models. It has two phases, a conventional approach such as unsupervised BIC-based is utilized in the first phase to detect speaker changes and train a Neural Network, while in the second phase, the output trained parameters from the Neural Network are used to predict next incoming audio stream. Using this approach, a comparable accuracy to similar BIC-based approaches is achieved with a significant improvement in terms of computation time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20network" title="artificial neural network">artificial neural network</a>, <a href="https://publications.waset.org/abstracts/search?q=diarization" title=" diarization"> diarization</a>, <a href="https://publications.waset.org/abstracts/search?q=speaker%20indexing" title=" speaker indexing"> speaker indexing</a>, <a href="https://publications.waset.org/abstracts/search?q=speaker%20segmentation" title=" speaker segmentation"> speaker segmentation</a> </p> <a href="https://publications.waset.org/abstracts/27191/a-two-step-framework-for-unsupervised-speaker-segmentation-using-bic-and-artificial-neural-network" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27191.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">502</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1449</span> Neuro-Preservation Potential of Resveratrol Against High Fat High Fructose-Induced Metabolic Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rania%20F.%20Ahmed">Rania F. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Sally%20A.%20El%20Awdan"> Sally A. El Awdan</a>, <a href="https://publications.waset.org/abstracts/search?q=Gehad%20A.%20Abdel%20Jaleel"> Gehad A. Abdel Jaleel</a>, <a href="https://publications.waset.org/abstracts/search?q=Dalia%20O.%20Saleh"> Dalia O. Saleh</a>, <a href="https://publications.waset.org/abstracts/search?q=Omar%20A.%20H.%20Ahmed-Farid"> Omar A. H. Ahmed-Farid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The metabolic syndrome is an important public health concern often related to obesity, improper diet, and sedentary lifestyles and can predispose individuals to the development of many dangerous health conditions, disability and early death. This research aimed to investigate the efficacy of resveratrol (RSV) to reverse the neuro-complications associated with metabolic syndrome experimentally-induced in rats using an eight weeks high fat, high fructose diet (HFHF) model. The corresponding drug treatments were administered orally during the last 10 days of the diet. Behavioural tests namely the open field test (OFT) and the forced swimming test (FST) were conducted. Brain levels of monoamines viz. serotonin, norepinephrine and dopamine as well as their metabolites were assessed. 8-hydroxyguanosine (8-OHDG) as an indicative of DNA-fragmentation, nitric oxide (NOx) and tumor necrosis factor-α (TNF- α) were estimated. Finally, brain antioxidant parameters namely malondialdehyde (MDA), reduced and oxidized glutathione (GSH, GSSG) were evaluated. HFHF-induced metabolic syndrome resulted in decreased activity in the OFT and increased immobility duration in the FST. Furthermore, HFHF-induced metabolic syndrome lead to a significant increase in brain monoamines turn over as well as elevation in 8-OHDG, NOx, TNF- α, MDA and GSSG; and reduction in GSH. Ten days daily treatment with RSV (20 and 40 mg/kg p.o) dose dependently increased activity in the OFT and decreased immobility duration in the FST. Moreover, RSV normalized brain monoamines contents, reduced 8-OHDG, NOx, TNF- α, MDA and GSSG; and elevated GSH. In conclusion, we can say that RSV showed neuro-protective properties against HFHF-induced metabolic syndrome represented by monoamines preservation, prevention of neurodegeneration, anti-inflammatory and antioxidant potentials and could be recommended as a beneficial daily dietary supplement to treat the neuronal side effects associated with HFHF-induced metabolic syndrome. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title="antioxidants">antioxidants</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA-fragmentation" title=" DNA-fragmentation"> DNA-fragmentation</a>, <a href="https://publications.waset.org/abstracts/search?q=forced%20swimming%20test" title=" forced swimming test"> forced swimming test</a>, <a href="https://publications.waset.org/abstracts/search?q=HFHF-induced%20metabolic%20syndrome" title=" HFHF-induced metabolic syndrome"> HFHF-induced metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=monoamines" title=" monoamines"> monoamines</a>, <a href="https://publications.waset.org/abstracts/search?q=nitric%20oxide%20%28NOx%29" title=" nitric oxide (NOx)"> nitric oxide (NOx)</a>, <a href="https://publications.waset.org/abstracts/search?q=open%20field" title=" open field"> open field</a>, <a href="https://publications.waset.org/abstracts/search?q=resveratrol" title=" resveratrol"> resveratrol</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20necrosis%20factor-%CE%B1%20%28TNF-%20%CE%B1%29" title=" tumor necrosis factor-α (TNF- α)"> tumor necrosis factor-α (TNF- α)</a>, <a href="https://publications.waset.org/abstracts/search?q=8-hydroxyguanosine%20%288-OHDG%29" title=" 8-hydroxyguanosine (8-OHDG)"> 8-hydroxyguanosine (8-OHDG)</a> </p> <a href="https://publications.waset.org/abstracts/56160/neuro-preservation-potential-of-resveratrol-against-high-fat-high-fructose-induced-metabolic-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56160.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">276</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1448</span> The Potential of M-Government towards Successful Implementation of E-Government in Saudi Arabia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Majed%20Ahmed%20Alfayad">Majed Ahmed Alfayad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Technology is now present in almost all areas and practices globally, and this has led governments around the world to adopt technology in the public sector. Therefore, electronic government has been introduced as a means of the automation of government services. New technologies and trends appear every single day, and governments need to meet the citizen’s requirements and expectations in order to succeed in the E-Government program. This research investigates the potential of mobile government as an enhancement force for the E-Government project in the Kingdom of Saudi Arabia, where the usage of mobile technology is coming to be favoured by citizens. Qualitative methodology has been adopted in this study for the data collection and analysis, and in particular the grounded theory approach. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=e-government" title="e-government">e-government</a>, <a href="https://publications.waset.org/abstracts/search?q=e-participation" title=" e-participation"> e-participation</a>, <a href="https://publications.waset.org/abstracts/search?q=m-government" title=" m-government"> m-government</a>, <a href="https://publications.waset.org/abstracts/search?q=mobile%20technology" title=" mobile technology"> mobile technology</a> </p> <a href="https://publications.waset.org/abstracts/36028/the-potential-of-m-government-towards-successful-implementation-of-e-government-in-saudi-arabia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36028.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1447</span> Pressure Gradient Prediction of Oil-Water Two Phase Flow through Horizontal Pipe</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20I.%20Raheem">Ahmed I. Raheem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this thesis, stratified and stratified wavy flow regimes have been investigated numerically for the oil (1.57 mPa s viscosity and 780 kg/m3 density) and water twophase flow in small and large horizontal steel pipes with a diameter between 0.0254 to 0.508 m by ANSYS Fluent software. Volume of fluid (VOF) with two phases flows using two equations family models (Realizable k- <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CFD" title="CFD">CFD</a>, <a href="https://publications.waset.org/abstracts/search?q=two-phase%20flow" title=" two-phase flow"> two-phase flow</a>, <a href="https://publications.waset.org/abstracts/search?q=pressure%20gradient" title=" pressure gradient"> pressure gradient</a>, <a href="https://publications.waset.org/abstracts/search?q=volume%20of%20fluid" title=" volume of fluid"> volume of fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=large%20diameter" title=" large diameter"> large diameter</a>, <a href="https://publications.waset.org/abstracts/search?q=horizontal%20pipe" title=" horizontal pipe"> horizontal pipe</a>, <a href="https://publications.waset.org/abstracts/search?q=oil-water%20stratified%20and%20stratified%20wavy%20flow" title=" oil-water stratified and stratified wavy flow "> oil-water stratified and stratified wavy flow </a> </p> <a href="https://publications.waset.org/abstracts/14937/pressure-gradient-prediction-of-oil-water-two-phase-flow-through-horizontal-pipe" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14937.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">433</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1446</span> Study the Multifaceted Therapeutic Properties of the IQGAP1shRNA Plasmid on Rat Liver Cancer Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Khairy%20M.%20A.%20Zoheir">Khairy M. A. Zoheir</a>, <a href="https://publications.waset.org/abstracts/search?q=Nehma%20A.%20Ali"> Nehma A. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20M.%20Darwish"> Ahmed M. Darwish</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20S.%20Kishta"> Mohamed S. Kishta</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20A.%20Abd-Rabou"> Ahmed A. Abd-Rabou</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20Abdelhafez"> Mohamed A. Abdelhafez</a>, <a href="https://publications.waset.org/abstracts/search?q=Karima%20F.%20Mahrous"> Karima F. Mahrous</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study comprehensively investigated the multifaceted therapeutic properties of the IQGAP1shRNA plasmid, encompassing its hepatoprotective, immunomodulatory, and anticancer activities. The study employed a Prednisolone-induced immunosuppressed rat model to assess the hepatoprotective and immunomodulatory effects of IQGAP1shRNA plasmid. Using this model, IQGAP1shRNA plasmid was found to modulate haematopoiesis, improving RBC, platelet, and WBC counts, underscoring its potential in hematopoietic homeostasis. Organ atrophy, a hallmark of immunosuppression in spleen, heart, liver, ovaries, and kidneys, was reversed with IQGAP1shRNA plasmid treatment, reinforcing its hepatotrophic and organotropic capabilities. Elevated hepatic biomarkers (ALT, AST, ALP, LPO) indicative of hepatocellular injury and oxidative stress were reduced with GST, highlighting its hepatoprotective and antioxidative effects. IQGAP1shRNA plasmid also restored depleted antioxidants (GSH and SOD), emphasizing its potent antioxidative and free radical scavenging capabilities. Molecular insights into immune dysregulation revealed downregulation of IQGAP1, IQGAP3 interleukin-2 (IL-2), and interleukin-4 (IL-4) mRNA expression in the liver of immunosuppressed rats. IL-2 and IL-4 play pivotal roles in immune regulation, T-cell activation, and B-cell differentiation. Notably, treatment with IQGAP1shRNA plasmid exhibited a significant upregulation of IL-2 and IL-4 mRNA expression, thereby accentuating its immunomodulatory potential in orchestrating immune homeostasis. Additionally, immune dysregulation was associated with increased levels of TNF-α. However, treatment with IQGAP1shRNA plasmid effectively decreased the levels of TNF-α, further underscoring its role in modulating inflammatory responses and restoring immune balance in immunosuppressed rats. Additionally, pharmacokinetics, bioavailability, drug-likeness, and toxicity risk assessment prediction suggest its potential as a pharmacologically favourable agent with no serious adverse effects. In conclusion, this study confirms the therapeutic potential of the IQGAP1shRNA plasmid, showcasing its effectiveness against hepatotoxicity, oxidative stress, immunosuppression, and its notable anticancer activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IQGAP1" title="IQGAP1">IQGAP1</a>, <a href="https://publications.waset.org/abstracts/search?q=shRNA" title=" shRNA"> shRNA</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer" title=" cancer"> cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=liver" title=" liver"> liver</a>, <a href="https://publications.waset.org/abstracts/search?q=rat" title=" rat"> rat</a> </p> <a href="https://publications.waset.org/abstracts/194910/study-the-multifaceted-therapeutic-properties-of-the-iqgap1shrna-plasmid-on-rat-liver-cancer-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194910.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">6</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1445</span> From the Local to the Global: New Terrorism </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shamila%20Ahmed">Shamila Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper examines how the fluidity between the local level and the global level is an intrinsic feature of new terrorism. Through using cosmopolitanism, the narratives of the two opposing sides of ISIS and the ‘war on terrorism’ response are explored. It is demonstrated how the fluidity between these levels facilitates the radicalisation process through exploring how groups such as ISIS highlight the perceived injustices against Muslims locally and globally and therefore exploit the globalisation process which has reduced the space between these levels. Similarly, it is argued that the ‘war on terror’ involves the intersection of fear, security, threat, risk and social control as features of both the international ‘war on terror’ and intra state policies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=terrorism" title="terrorism">terrorism</a>, <a href="https://publications.waset.org/abstracts/search?q=war%20on%20terror" title=" war on terror"> war on terror</a>, <a href="https://publications.waset.org/abstracts/search?q=cosmopolitanism" title=" cosmopolitanism"> cosmopolitanism</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20level%20terrorism" title=" global level terrorism"> global level terrorism</a> </p> <a href="https://publications.waset.org/abstracts/28001/from-the-local-to-the-global-new-terrorism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28001.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">585</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1444</span> The Conjugated Polymers in improving the Organic Solar Cells Efficiency</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samia%20Moulebhar">Samia Moulebhar</a>, <a href="https://publications.waset.org/abstracts/search?q=Chahrazed%20Bendenia"> Chahrazed Bendenia</a>, <a href="https://publications.waset.org/abstracts/search?q=Souhila%20Bendenia"> Souhila Bendenia</a>, <a href="https://publications.waset.org/abstracts/search?q=Hanaa%20Merad-dib"> Hanaa Merad-dib</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarra%20Merabet"> Sarra Merabet</a>, <a href="https://publications.waset.org/abstracts/search?q=Sid%20Ahmed%20Khantar"> Sid Ahmed Khantar</a>, <a href="https://publications.waset.org/abstracts/search?q=Baghdad%20Hadri"> Baghdad Hadri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The photovoltaic solar field is today experiencing exponential advancement with the exploitation of new technological sectors of nanoparticles, namely the field of solar cells based on organic polymer materials. These cells are flexible, easy to process and low cost. This work includes a presentation of the conjugated polymer materials used in the design of photovoltaic technology devices while determining their properties and then the models used for the modeling of thin film photovoltaic cells heterojunction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=photovoltaic" title="photovoltaic">photovoltaic</a>, <a href="https://publications.waset.org/abstracts/search?q=cells" title=" cells"> cells</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=organic" title=" organic"> organic</a> </p> <a href="https://publications.waset.org/abstracts/174383/the-conjugated-polymers-in-improving-the-organic-solar-cells-efficiency" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">85</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1443</span> The Protection and Enhancement of the Roman Roads in Algeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tarek%20Ninouh">Tarek Ninouh</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Rouili"> Ahmed Rouili</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Roman paths or roads offer a very interesting archaeological material, because they allow us to understand the history of human settlement and are also factors that increase territorial identity. Roman roads are one of the hallmarks of the Roman empire, which extends to North Africa. The objective of this investigation is to attract the attention of researchers to the importance of Roman roads and paths, which are found in Algeria, according to the quality of the materials and techniques used in this period of our history, and to encourage other decision makers to protect and enhance these routes because the current urbanization, intensive agricultural practices, or simply forgotten, decreases the sustainability of this important historical heritage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Roman%20paths" title="Roman paths">Roman paths</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20materials" title=" quality of materials"> quality of materials</a>, <a href="https://publications.waset.org/abstracts/search?q=property" title=" property"> property</a>, <a href="https://publications.waset.org/abstracts/search?q=valuation" title=" valuation"> valuation</a> </p> <a href="https://publications.waset.org/abstracts/1863/the-protection-and-enhancement-of-the-roman-roads-in-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1863.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">430</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1442</span> A Simulated Evaluation of Model Predictive Control</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20AlNouss">Ahmed AlNouss</a>, <a href="https://publications.waset.org/abstracts/search?q=Salim%20Ahmed"> Salim Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Process control refers to the techniques to control the variables in a process in order to maintain them at their desired values. Advanced process control (APC) is a broad term within the domain of control where it refers to different kinds of process control and control related tools, for example, model predictive control (MPC), statistical process control (SPC), fault detection and classification (FDC) and performance assessment. APC is often used for solving multivariable control problems and model predictive control (MPC) is one of only a few advanced control methods used successfully in industrial control applications. Advanced control is expected to bring many benefits to the plant operation; however, the extent of the benefits is plant specific and the application needs a large investment. This requires an analysis of the expected benefits before the implementation of the control. In a real plant simulation studies are carried out along with some experimentation to determine the improvement in the performance of the plant due to advanced control. In this research, such an exercise is undertaken to realize the needs of APC application. The main objectives of the paper are as follows: (1) To apply MPC to a number of simulations set up to realize the need of MPC by comparing its performance with that of proportional integral derivatives (PID) controllers. (2) To study the effect of controller parameters on control performance. (3) To develop appropriate performance index (PI) to compare the performance of different controller and develop novel idea to present tuning map of a controller. These objectives were achieved by applying PID controller and a special type of MPC which is dynamic matrix control (DMC) on the multi-tanks process simulated in loop-pro. Then the controller performance has been evaluated by changing the controller parameters. This performance was based on special indices related to the difference between set point and process variable in order to compare the both controllers. The same principle was applied for continuous stirred tank heater (CSTH) and continuous stirred tank reactor (CSTR) processes simulated in Matlab. However, in these processes some developed programs were written to evaluate the performance of the PID and MPC controllers. Finally these performance indices along with their controller parameters were plotted using special program called Sigmaplot. As a result, the improvement in the performance of the control loops was quantified using relevant indices to justify the need and importance of advanced process control. Also, it has been approved that, by using appropriate indices, predictive controller can improve the performance of the control loop significantly. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=advanced%20process%20control%20%28APC%29" title="advanced process control (APC)">advanced process control (APC)</a>, <a href="https://publications.waset.org/abstracts/search?q=control%20loop" title=" control loop"> control loop</a>, <a href="https://publications.waset.org/abstracts/search?q=model%20predictive%20control%20%28MPC%29" title=" model predictive control (MPC)"> model predictive control (MPC)</a>, <a href="https://publications.waset.org/abstracts/search?q=proportional%20integral%20derivatives%20%28PID%29" title=" proportional integral derivatives (PID)"> proportional integral derivatives (PID)</a>, <a href="https://publications.waset.org/abstracts/search?q=performance%20indices%20%28PI%29" title=" performance indices (PI)"> performance indices (PI)</a> </p> <a href="https://publications.waset.org/abstracts/12882/a-simulated-evaluation-of-model-predictive-control" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12882.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">407</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1441</span> Low Voltage Ride through Capability Techniques for DFIG-Based Wind Turbines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sherif%20O.%20Zain%20Elabideen">Sherif O. Zain Elabideen</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20A.%20Helal"> Ahmed A. Helal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20F.%20El-Arabawy"> Ibrahim F. El-Arabawy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Due to the drastic increase of the wind turbines installed capacity; the grid codes are increasing the restrictions aiming to treat the wind turbines like other conventional sources sooner. In this paper, an intensive review has been presented for different techniques used to add low voltage ride through capability to Doubly Fed Induction Generator (DFIG) wind turbine. A system model with 1.5 MW DFIG wind turbine is constructed and simulated using MATLAB/SIMULINK to explore the effectiveness of the reviewed techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DFIG" title="DFIG">DFIG</a>, <a href="https://publications.waset.org/abstracts/search?q=grid%20side%20converters" title=" grid side converters"> grid side converters</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20voltage%20ride%20through" title=" low voltage ride through"> low voltage ride through</a>, <a href="https://publications.waset.org/abstracts/search?q=wind%20turbine" title=" wind turbine"> wind turbine</a> </p> <a href="https://publications.waset.org/abstracts/49677/low-voltage-ride-through-capability-techniques-for-dfig-based-wind-turbines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/49677.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1440</span> Parallel Multisplitting Methods for DAE’s</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Machmoum">Ahmed Machmoum</a>, <a href="https://publications.waset.org/abstracts/search?q=Malika%20El%20Kyal"> Malika El Kyal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We consider iterative parallel multi-splitting method for differential algebraic equations. The main feature of the proposed idea is to use the asynchronous form. We prove that the multi-splitting technique can effectively accelerate the convergent performance of the iterative process. The main characteristic of an asynchronous mode is that the local algorithm not have to wait at predetermined messages to become available. We allow some processors to communicate more frequently than others, and we allow the communication delays tobe substantial and unpredictable. Note that synchronous algorithms in the computer science sense are particular cases of our formulation of asynchronous one. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=computer" title="computer">computer</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-splitting%20methods" title=" multi-splitting methods"> multi-splitting methods</a>, <a href="https://publications.waset.org/abstracts/search?q=asynchronous%20mode" title=" asynchronous mode"> asynchronous mode</a>, <a href="https://publications.waset.org/abstracts/search?q=differential%20algebraic%20systems" title=" differential algebraic systems "> differential algebraic systems </a> </p> <a href="https://publications.waset.org/abstracts/23813/parallel-multisplitting-methods-for-daes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23813.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">549</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1439</span> SOTM: A New Cooperation Based Trust Management System for VANET</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amel%20Ltifi">Amel Ltifi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Zouinkhi"> Ahmed Zouinkhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Salim%20Bouhlel"> Mohamed Salim Bouhlel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Security and trust management in Vehicular Ad-hoc NETworks (VANET) is a crucial research domain which is the scope of many researches and domains. Although, the majority of the proposed trust management systems for VANET are based on specific road infrastructure, which may not be present in all the roads. Therefore, road security should be managed by vehicles themselves. In this paper, we propose a new Self Organized Trust Management system (SOTM). This system has the responsibility to cut with the spread of false warnings in the network through four principal components: cooperation, trust management, communication and security. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ative%20vehicle" title="ative vehicle">ative vehicle</a>, <a href="https://publications.waset.org/abstracts/search?q=cooperation" title=" cooperation"> cooperation</a>, <a href="https://publications.waset.org/abstracts/search?q=trust%20management" title=" trust management"> trust management</a>, <a href="https://publications.waset.org/abstracts/search?q=VANET" title=" VANET"> VANET</a> </p> <a href="https://publications.waset.org/abstracts/42267/sotm-a-new-cooperation-based-trust-management-system-for-vanet" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42267.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">430</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1438</span> Viability of EBT3 Film in Small Dimensions to Be Use for in-Vivo Dosimetry in Radiation Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdul%20Qadir%20Jangda">Abdul Qadir Jangda</a>, <a href="https://publications.waset.org/abstracts/search?q=Khadija%20Mariam"> Khadija Mariam</a>, <a href="https://publications.waset.org/abstracts/search?q=Usman%20Ahmed"> Usman Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Sharib%20Ahmed"> Sharib Ahmed </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Gafchromic EBT3 film has the characteristic of high spatial resolution, weak energy dependence and near tissue equivalence which makes them viable to be used for in-vivo dosimetry in External Beam and Brachytherapy applications. The aim of this study is to assess the smallest film dimension that may be feasible for the use in in-vivo dosimetry. To evaluate the viability, the film sizes from 3 x 3 mm to 20 x 20 mm were calibrated with 6 MV Photon and 6 MeV electron beams. The Gafchromic EBT3 (Lot no. A05151201, Make: ISP) film was cut into five different sizes in order to establish the relationship between absorbed dose vs. film dimensions. The film dimension were 3 x 3, 5 x 5, 10 x 10, 15 x 15, and 20 x 20 mm. The films were irradiated on Varian Clinac® 2100C linear accelerator for dose range from 0 to 1000 cGy using PTW solid water phantom. The irradiation was performed as per clinical absolute dose rate calibratin setup, i.e. 100 cm SAD, 5.0 cm depth and field size of 10x10 cm2 and 100 cm SSD, 1.4 cm depth and 15x15 cm2 applicator for photon and electron respectively. The irradiated films were scanned with the landscape orientation and a post development time of 48 hours (minimum). Film scanning accomplished using Epson Expression 10000 XL Flatbed Scanner and quantitative analysis carried out with ImageJ freeware software. Results show that the dose variation with different film dimension ranging from 3 x 3 mm to 20 x 20 mm is very minimal with a maximum standard deviation of 0.0058 in Optical Density for a dose level of 3000 cGy and the the standard deviation increases with the increase in dose level. So the precaution must be taken while using the small dimension films for higher doses. Analysis shows that there is insignificant variation in the absorbed dose with a change in film dimension of EBT3 film. Study concludes that the film dimension upto 3 x 3 mm can safely be used up to a dose level of 3000 cGy without the need of recalibration for particular dimension in use for dosimetric application. However, for higher dose levels, one may need to calibrate the films for a particular dimension in use for higher accuracy. It was also noticed that the crystalline structure of the film got damage at the edges while cutting the film, which can contribute to the wrong dose if the region of interest includes the damage area of the film <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=external%20beam%20radiotherapy" title="external beam radiotherapy">external beam radiotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=film%20calibration" title=" film calibration"> film calibration</a>, <a href="https://publications.waset.org/abstracts/search?q=film%20dosimetery" title=" film dosimetery"> film dosimetery</a>, <a href="https://publications.waset.org/abstracts/search?q=in-vivo%20dosimetery" title=" in-vivo dosimetery "> in-vivo dosimetery </a> </p> <a href="https://publications.waset.org/abstracts/24104/viability-of-ebt3-film-in-small-dimensions-to-be-use-for-in-vivo-dosimetry-in-radiation-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24104.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">494</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1437</span> Impact of Implementation of Right to Education in Pakistan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rukhsar%20Ahmed">Rukhsar Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Jawed%20Aziz%20Masudi"> Jawed Aziz Masudi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the present study, an attempt has been made about the right to an education in Pakistan. The research is the focus in respect of International Law Article 26 of the Universal Declaration of Human Rights. The main motivation behind getting great training is, as a rule, decent resident and afterward being effective in close to home and expert life. We are fragmented without decent instruction since training makes us the right mastermind and right chief. In such a focused world, instruction has turned into a need for people after sustenance, dress and haven. It can give answers for all issues; it advances great propensities and mindfulness about defilement, fear-mongering, and other social issues among us. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=right%20to%20education" title=" right to education"> right to education</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20right" title=" human right"> human right</a>, <a href="https://publications.waset.org/abstracts/search?q=universal%20declaration" title=" universal declaration"> universal declaration</a>, <a href="https://publications.waset.org/abstracts/search?q=law" title=" law"> law</a> </p> <a href="https://publications.waset.org/abstracts/147511/impact-of-implementation-of-right-to-education-in-pakistan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147511.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1436</span> Modeling of Crack Growth in Railway Axles under Static Loading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zellagui%20Redouane">Zellagui Redouane</a>, <a href="https://publications.waset.org/abstracts/search?q=Bellaouar%20Ahmed"> Bellaouar Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Lachi%20Mohammed"> Lachi Mohammed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The railway axles are the essential parts in the bogie of train, and its failure creates a big problem in the railway transport; during the work of this parts we noticed a premature deterioration. The aim has been presented a predictive model allowing the identification of the probable causes that are the cause of these premature deterioration. The results are employed for predicting fatigue crack growth in the railway axle, Also we want to present the variation value of stress intensity factor in different positions of elliptical crack tip. The modeling of axle in performed by the SOLID WORKS software and imported into ANSYS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=crack%20growth" title="crack growth">crack growth</a>, <a href="https://publications.waset.org/abstracts/search?q=static%20load" title=" static load"> static load</a>, <a href="https://publications.waset.org/abstracts/search?q=railway%20axle" title=" railway axle"> railway axle</a>, <a href="https://publications.waset.org/abstracts/search?q=lifetime" title=" lifetime"> lifetime</a> </p> <a href="https://publications.waset.org/abstracts/63837/modeling-of-crack-growth-in-railway-axles-under-static-loading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63837.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">364</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1435</span> BER Estimate of WCDMA Systems with MATLAB Simulation Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Suyeb%20Ahmed%20Khan">Suyeb Ahmed Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmood%20Mian"> Mahmood Mian</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Simulation plays an important role during all phases of the design and engineering of communications systems, from early stages of conceptual design through the various stages of implementation, testing, and fielding of the system. In the present paper, a simulation model has been constructed for the WCDMA system in order to evaluate the performance. This model describes multiusers effects and calculation of BER (Bit Error Rate) in 3G mobile systems using Simulink MATLAB 7.1. Gaussian Approximation defines the multi-user effect on system performance. BER has been analyzed with comparison between transmitting data and receiving data. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=WCDMA" title="WCDMA">WCDMA</a>, <a href="https://publications.waset.org/abstracts/search?q=simulations" title=" simulations"> simulations</a>, <a href="https://publications.waset.org/abstracts/search?q=BER" title=" BER"> BER</a>, <a href="https://publications.waset.org/abstracts/search?q=MATLAB" title=" MATLAB"> MATLAB</a> </p> <a href="https://publications.waset.org/abstracts/24549/ber-estimate-of-wcdma-systems-with-matlab-simulation-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24549.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">592</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1434</span> A Multi Cordic Architecture on FPGA Platform </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Madian">Ahmed Madian</a>, <a href="https://publications.waset.org/abstracts/search?q=Muaz%20Aljarhi"> Muaz Aljarhi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Coordinate Rotation Digital Computer (CORDIC) is a unique digital computing unit intended for the computation of mathematical operations and functions. This paper presents a multi-CORDIC processor that integrates different CORDIC architectures on a single FPGA chip and allows the user to select the CORDIC architecture to proceed with based on what he wants to calculate and his/her needs. Synthesis show that radix 2 CORDIC has the lowest clock delay, radix 8 CORDIC has the highest LUT usage and lowest register usage while Hybrid Radix 4 CORDIC had the highest clock delay. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=multi" title="multi">multi</a>, <a href="https://publications.waset.org/abstracts/search?q=CORDIC" title=" CORDIC"> CORDIC</a>, <a href="https://publications.waset.org/abstracts/search?q=FPGA" title=" FPGA"> FPGA</a>, <a href="https://publications.waset.org/abstracts/search?q=processor" title=" processor"> processor</a> </p> <a href="https://publications.waset.org/abstracts/2193/a-multi-cordic-architecture-on-fpga-platform" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2193.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">470</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1433</span> An Analysis and Design of Mobile Payment System Based on NFC Technology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shafiq%20ur%20Rehman">Shafiq ur Rehman</a>, <a href="https://publications.waset.org/abstracts/search?q=Zubair%20Ahmed%20Shaikh"> Zubair Ahmed Shaikh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This research provides the comparative study of different mobile payment system and proposes an efficient solution of mobile payment system. The research involves discovering how the mobile payment methods can be used and implemented keeping user and system interaction under consideration. The implementation of Nielsen’s heuristic and universal design principles enhanced the user’s interaction design and made the system more appropriate, understandable and visible to the end user. The design of application is greatly affected by the user driven factors. These factors help in the efficiency of the application usage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mobile%20payment%20system" title="mobile payment system">mobile payment system</a>, <a href="https://publications.waset.org/abstracts/search?q=m-commerce" title=" m-commerce"> m-commerce</a>, <a href="https://publications.waset.org/abstracts/search?q=usability" title=" usability"> usability</a>, <a href="https://publications.waset.org/abstracts/search?q=near%20field%20communication" title=" near field communication"> near field communication</a> </p> <a href="https://publications.waset.org/abstracts/8689/an-analysis-and-design-of-mobile-payment-system-based-on-nfc-technology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8689.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">452</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1432</span> Performance Analysis of SAC-OCDMA System using Different Detectors </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Somaya%20A.%20Abd%20El%20Mottaleb">Somaya A. Abd El Mottaleb</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Abd%20El%20Aziz"> Ahmed Abd El Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20A.%20Fayed"> Heba A. Fayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Moustafa%20H.%20Aly">Moustafa H. Aly</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, we present the performance of spectral amplitude coding optical code division multiple access using different detectors at different transmission distances using single photodiode detection technique. Modified double weight codes are used as signature codes. Simulation results show that the system using avalanche photo detector can move distance longer than that using positive intrinsic negative photo detector. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=avalanche%20photodiode" title="avalanche photodiode">avalanche photodiode</a>, <a href="https://publications.waset.org/abstracts/search?q=modified%20double%20weight" title=" modified double weight"> modified double weight</a>, <a href="https://publications.waset.org/abstracts/search?q=multiple%20access%20technique" title=" multiple access technique"> multiple access technique</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20photodiode." title=" single photodiode. "> single photodiode. </a> </p> <a href="https://publications.waset.org/abstracts/12035/performance-analysis-of-sac-ocdma-system-using-different-detectors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12035.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">605</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1431</span> Mechanisms of Cultural Change Resistance through Cultures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Horaya%20Mostafa%20Ahmed">Horaya Mostafa Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> All cultures are inherently predisposed to change and, at the same time, to resisting change. There are dynamic processes operating that encourage the acceptance of new ideas and things, while there are others that encourage changeless stability. Despite the dramatic changes that have taken place in all human cultures, there are cultures still steadfast and resist change. These cultures resist through some culture mechanisms like, cultural boundaries, ethnocentrism, religion, and cultural relativity. So this paper is an attempt to discover these mechanisms of cultural change resistance and to ask is cultural change always required. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cultural%20change" title="cultural change">cultural change</a>, <a href="https://publications.waset.org/abstracts/search?q=cultural%20boundaries" title=" cultural boundaries"> cultural boundaries</a>, <a href="https://publications.waset.org/abstracts/search?q=cultural%20relativity" title=" cultural relativity"> cultural relativity</a>, <a href="https://publications.waset.org/abstracts/search?q=ethnocentrism" title=" ethnocentrism"> ethnocentrism</a>, <a href="https://publications.waset.org/abstracts/search?q=religion" title=" religion"> religion</a>, <a href="https://publications.waset.org/abstracts/search?q=resistance" title=" resistance"> resistance</a> </p> <a href="https://publications.waset.org/abstracts/44362/mechanisms-of-cultural-change-resistance-through-cultures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44362.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">340</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1430</span> A Secure Digital Signature Scheme with Fault Tolerance Based on the Improved RSA System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20El-Kamchouchi">H. El-Kamchouchi</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20Gaber"> Heba Gaber</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatma%20Ahmed"> Fatma Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Dalia%20H.%20El-Kamchouchi"> Dalia H. El-Kamchouchi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Fault tolerance and data security are two important issues in modern communication systems. In this paper, we propose a secure and efficient digital signature scheme with fault tolerance based on the improved RSA system. The proposed scheme for the RSA cryptosystem contains three prime numbers and overcome several attacks possible on RSA. By using the Chinese Reminder Theorem (CRT) the proposed scheme has a speed improvement on the RSA decryption side and it provides high security also. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=digital%20signature" title="digital signature">digital signature</a>, <a href="https://publications.waset.org/abstracts/search?q=fault%20tolerance" title=" fault tolerance"> fault tolerance</a>, <a href="https://publications.waset.org/abstracts/search?q=RSA" title=" RSA"> RSA</a>, <a href="https://publications.waset.org/abstracts/search?q=security%20analysis" title=" security analysis"> security analysis</a> </p> <a href="https://publications.waset.org/abstracts/51269/a-secure-digital-signature-scheme-with-fault-tolerance-based-on-the-improved-rsa-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51269.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">476</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1429</span> Total Arterial Coronary Revascularization with Aorto-Bifemoral Bipopliteal Bypass: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nuruddin%20Mohammod%20Zahangir">Nuruddin Mohammod Zahangir</a>, <a href="https://publications.waset.org/abstracts/search?q=Syed%20Tanvir%20Ahmady"> Syed Tanvir Ahmady</a>, <a href="https://publications.waset.org/abstracts/search?q=Firoz%20Ahmed"> Firoz Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mainul%20Kabir"> Mainul Kabir</a>, <a href="https://publications.waset.org/abstracts/search?q=Tamjid%20Mohammad%20Najmus%20Sakib%20Khan"> Tamjid Mohammad Najmus Sakib Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazmul%20Hossain"> Nazmul Hossain</a>, <a href="https://publications.waset.org/abstracts/search?q=Niaz%20Ahmed"> Niaz Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Madhava%20Janardhan%20Naik"> Madhava Janardhan Naik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The management of combined Coronary Artery Disease and Peripheral Vascular Disease is a challenge and brings with it numerous clinical dilemmas.The 56 year old gentleman presented to our department with significant triple vessel disease with occluded lower end of aorta just before bifurcation and bilateral superficial femoral arteries. Operation was done on 11.03.14. The The Left Internal Mammary Artery (LIMA) and the Right Internal Mammary Artery (RIMA) were harvested in skeletonized manner. The free RIMA was then anastomosed with LIMA to make LIMA-RIMA Y. Cardio Pulmonary Bypass was then established and coronary artery bypass grafts performed. LIMA was anastomosed to the Left Anterior Descending artery. RIMA was anastomosed to Posterior Descending Artery, 1st and 2nd Obtuse Marginal arteries in a sequential manner. Abdomen was opened by midline incision. The infrarenal aorta exposed and was found to be severely diseased. A Vascular Clamp was applied infrarenally, aortotomy done and limited endarterectomy performed. An end-to-side anastomosis was done with upper end of PTFE synthetic Y-graft (14/7 mm) to the infarenal Aorta and the Clamp released. Good flow noted in both limbs of the graft. Patient was then slowly weaned off from Cardio Pulmonary Bypass without difficulty. The distal two limbs of the Y graft were passed to the groin through retroperitoneal tunnels and anastomosed end-to-side with the common femoral arteries. Saphenous vein was interposed between common femoral and popliteal arteries bilaterally through subfascial tunnels in both thigh. On 12th postoperative day he was discharged from hospital in good general condition. Follow up after 3 months of operation the patient is doing good and free of chest pain and claudication pain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=total%20arterial" title="total arterial">total arterial</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20revascularization" title=" coronary revascularization"> coronary revascularization</a>, <a href="https://publications.waset.org/abstracts/search?q=aorto-bifemoral%20bypass" title=" aorto-bifemoral bypass"> aorto-bifemoral bypass</a>, <a href="https://publications.waset.org/abstracts/search?q=bifemoro-bipopliteal%20bypass" title=" bifemoro-bipopliteal bypass"> bifemoro-bipopliteal bypass</a> </p> <a href="https://publications.waset.org/abstracts/12890/total-arterial-coronary-revascularization-with-aorto-bifemoral-bipopliteal-bypass-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12890.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">472</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1428</span> Fast Accurate Detection of Frequency Jumps Using Kalman Filter with Non Linear Improvements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahmoud%20E.%20Mohamed">Mahmoud E. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20F.%20Shalash"> Ahmed F. Shalash</a>, <a href="https://publications.waset.org/abstracts/search?q=Hanan%20A.%20Kamal"> Hanan A. Kamal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In communication systems, frequency jump is a serious problem caused by the oscillators used. Kalman filters are used to detect that jump, Despite the tradeoff between the noise level and the speed of the detection. In this paper, An improvement is introduced in the Kalman filter, Through a nonlinear change in the bandwidth of the filter. Simulation results show a considerable improvement in the filter speed with a very low noise level. Additionally, The effect on the response to false alarms is also presented and false alarm rate show improvement. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kalman%20filter" title="Kalman filter">Kalman filter</a>, <a href="https://publications.waset.org/abstracts/search?q=innovation" title=" innovation"> innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=false%20detection" title=" false detection"> false detection</a>, <a href="https://publications.waset.org/abstracts/search?q=improvement" title=" improvement "> improvement </a> </p> <a href="https://publications.waset.org/abstracts/7978/fast-accurate-detection-of-frequency-jumps-using-kalman-filter-with-non-linear-improvements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7978.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">602</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1427</span> Numerical Simulation of a Solar Photovoltaic Panel Cooled by a Forced Air System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Djamila%20Nebbali">Djamila Nebbali</a>, <a href="https://publications.waset.org/abstracts/search?q=Rezki%20Nebbali"> Rezki Nebbali</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Ouibrahim"> Ahmed Ouibrahim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study focuses on the cooling of a photovoltaic panel (PV). Indeed, the cooling improves the conversion capacity of this one and maintains, under extreme conditions of air temperature, the panel temperature at an appreciable level which avoids the altering. To do this, a fan provides forced circulation of air. Because the fan is supplied by the panel, it is necessary to determine the optimum operating point that unites efficiency of the PV with the consumption of the fan. For this matter, numerical simulations are performed at varying mass flow rates of air, under two extreme air temperatures (50°C, 25°C) and a fixed solar radiation (1000 W.m2) in a case of no wind. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=energy%20conversion" title="energy conversion">energy conversion</a>, <a href="https://publications.waset.org/abstracts/search?q=efficiency" title=" efficiency"> efficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=balance%20energy" title=" balance energy"> balance energy</a>, <a href="https://publications.waset.org/abstracts/search?q=solar%20cell" title=" solar cell"> solar cell</a> </p> <a href="https://publications.waset.org/abstracts/15688/numerical-simulation-of-a-solar-photovoltaic-panel-cooled-by-a-forced-air-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15688.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">416</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1426</span> Tracking Maximum Power Point Utilizing Artificial Immunity System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marwa%20Ahmed%20Abd%20El%20Hamied">Marwa Ahmed Abd El Hamied</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper In this paper, a new technique based on Artificial Immunity System (AIS) technique has been developed to track Maximum Power Point (MPP). AIS system is implemented in a photovoltaic system that is subjected to variable temperature and insulation condition. The proposed novel is simulated using Mat Lab program. The results of simulation have been compared to those who are generated from Observation Controller. The proposed model shows promising results as it provide better accuracy comparing to classical model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=component" title="component">component</a>, <a href="https://publications.waset.org/abstracts/search?q=artificial%20immunity%20technique" title=" artificial immunity technique"> artificial immunity technique</a>, <a href="https://publications.waset.org/abstracts/search?q=solar%0D%0Aenergy" title=" solar energy"> solar energy</a>, <a href="https://publications.waset.org/abstracts/search?q=perturbation%20and%20observation" title=" perturbation and observation"> perturbation and observation</a>, <a href="https://publications.waset.org/abstracts/search?q=power%20based%20methods" title=" power based methods"> power based methods</a> </p> <a href="https://publications.waset.org/abstracts/32619/tracking-maximum-power-point-utilizing-artificial-immunity-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32619.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">427</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1425</span> In Silico Analysis of Deleterious nsSNPs (Missense) of Dihydrolipoamide Branched-Chain Transacylase E2 Gene Associated with Maple Syrup Urine Disease Type II</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zainab%20S.%20Ahmed">Zainab S. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20S.%20Ali"> Mohammed S. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadia%20A.%20Elshiekh"> Nadia A. Elshiekh</a>, <a href="https://publications.waset.org/abstracts/search?q=Sami%20Adam%20Ibrahim"> Sami Adam Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghada%20M.%20El-Tayeb"> Ghada M. El-Tayeb</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20H.%20Elsadig"> Ahmed H. Elsadig</a>, <a href="https://publications.waset.org/abstracts/search?q=Rihab%20A.%20Omer"> Rihab A. Omer</a>, <a href="https://publications.waset.org/abstracts/search?q=Sofia%20B.%20Mohamed"> Sofia B. Mohamed </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Maple syrup urine (MSUD) is an autosomal recessive disease that causes a deficiency in the enzyme branched-chain alpha-keto acid (BCKA) dehydrogenase. The development of disease has been associated with SNPs in the DBT gene. Despite that, the computational analysis of SNPs in coding and noncoding and their functional impacts on protein level still remains unknown. Hence, in this study, we carried out a comprehensive in silico analysis of missense that was predicted to have a harmful influence on DBT structure and function. In this study, eight different in silico prediction algorithms; SIFT, PROVEAN, MutPred, SNP&GO, PhD-SNP, PANTHER, I-Mutant 2.0 and MUpo were used for screening nsSNPs in DBT including. Additionally, to understand the effect of mutations in the strength of the interactions that bind protein together the ELASPIC servers were used. Finally, the 3D structure of DBT was formed using Mutation3D and Chimera servers respectively. Our result showed that a total of 15 nsSNPs confirmed by 4 software (R301C, R376H, W84R, S268F, W84C, F276C, H452R, R178H, I355T, V191G, M444T, T174A, I200T, R113H, and R178C) were found damaging and can lead to a shift in DBT gene structure. Moreover, we found 7 nsSNPs located on the 2-oxoacid_dh catalytic domain, 5 nsSNPs on the E_3 binding domain and 3 nsSNPs on the Biotin Domain. So these nsSNPs may alter the putative structure of DBT’s domain. Furthermore, we detected all these nsSNPs are on the core residues of the protein and have the ability to change the stability of the protein. Additionally, we found W84R, S268F, and M444T have high significance, and they affected Leucine, Isoleucine, and Valine, which reduces or disrupt the function of BCKD complex, E2-subunit which the DBT gene encodes. In conclusion, based on our extensive in-silico analysis, we report 15 nsSNPs that have possible association with protein deteriorating and disease-causing abilities. These candidate SNPs can aid in future studies on Maple Syrup Urine Disease type II base in the genetic level. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DBT%20gene" title="DBT gene">DBT gene</a>, <a href="https://publications.waset.org/abstracts/search?q=ELASPIC" title=" ELASPIC"> ELASPIC</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20silico%20analysis" title=" in silico analysis"> in silico analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=UCSF%20chimer" title=" UCSF chimer"> UCSF chimer</a> </p> <a href="https://publications.waset.org/abstracts/83720/in-silico-analysis-of-deleterious-nssnps-missense-of-dihydrolipoamide-branched-chain-transacylase-e2-gene-associated-with-maple-syrup-urine-disease-type-ii" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83720.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">201</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mbarek%20Kaouther&page=5" rel="prev">&lsaquo;</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mbarek%20Kaouther&page=1">1</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mbarek%20Kaouther&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mbarek%20Kaouther&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mbarek%20Kaouther&page=4">4</a></li> <li class="page-item"><a class="page-link" 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