About RRG — CIMT

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class="Header-nav-folder-item" data-test="template-nav">MIATA</a> </span> </span><span class="Header-nav-item Header-nav-item--folder"> <a href="/rrg-3" class="Header-nav-folder-title Header-nav-folder-title--active" data-controller="HeaderNavFolderTouch">//RRG</a> <span class="Header-nav-folder"> <a href="/rrg-2" class="Header-nav-folder-item Header-nav-folder-item--active" data-test="template-nav">About RRG</a> <a href="/members" class="Header-nav-folder-item" data-test="template-nav">Members</a> <a href="/activities" class="Header-nav-folder-item" data-test="template-nav">Activities</a> </span> </span> </div> </nav> </div> </div> </header> <div class="Content-outer"> <main class="Main Main--page" > <section class="Main-content" data-content-field="main-content"> <div class="sqs-layout sqs-grid-12 columns-12" data-type="page" data-updated-on="1691489529036" id="page-5b6abc52575d1fcbf2453061"><div class="row sqs-row"><div class="col sqs-col-3 span-3"><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-1b8bb772709238cbcb12"><div class="sqs-block-content"> </div></div></div><div class="col sqs-col-6 span-6"><div class="row sqs-row"><div class="col sqs-col-5 span-5"><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-yui_3_17_2_1_1534852863788_17790"><div class="sqs-block-content"> </div></div></div><div class="col sqs-col-1 span-1"><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-yui_3_17_2_1_1533806820467_20251"><div class="sqs-block-content"> </div></div></div></div><div class="sqs-block code-block sqs-block-code" data-block-type="23" id="block-yui_3_17_2_1_1533807805902_42246"><div class="sqs-block-content"><p id="About RRG"><h1 id_"yui_3_17_2_1_1530605964027_1149">About RRG</h1></p> </div></div><div class="sqs-block html-block sqs-block-html" data-block-type="2" data-border-radii="{"topLeft":{"unit":"px","value":0.0},"topRight":{"unit":"px","value":0.0},"bottomLeft":{"unit":"px","value":0.0},"bottomRight":{"unit":"px","value":0.0}}" id="block-yui_3_17_2_1_1554725216004_10028"><div class="sqs-block-content"> <div class="sqs-html-content"> <p class="" style="white-space:pre-wrap;">Founded in 2008, the CIMT Regulatory Research Group is an independent group of experts focusing on regulatory aspects of drug development:</p><ul data-rte-list="default"><li><p class="" style="white-space:pre-wrap;">identifying regulatory challenges posed by emerging immunotherapies</p></li><li><p class="" style="white-space:pre-wrap;">developing new regulatory concepts to facilitate clinical testing of innovative immunotherapies</p></li><li><p class="" style="white-space:pre-wrap;">facilitating discussion between all groups relevant for the translation of scientific knowledge from bench to bedside</p></li></ul><p class="" style="white-space:pre-wrap;">The group is open to any expert committed to contributing to the RRG goals. All RRG activities are intended to support the scientific or medical progress in the field of immunotherapy. Independency and transparency are basic principles on which all RRG activities are based. The group discusses the generic principles and publicly available information on national and international laws, directives and regulations influencing the development of immunotherapy. All relevant activities of the group are made publicly available.</p> </div> </div></div><div class="sqs-block horizontalrule-block sqs-block-horizontalrule" data-block-type="47" id="block-5277a7eea72dac0d8c3e"><div class="sqs-block-content"><hr /></div></div><div class="sqs-block html-block sqs-block-html" data-block-type="2" data-border-radii="{"topLeft":{"unit":"px","value":0.0},"topRight":{"unit":"px","value":0.0},"bottomLeft":{"unit":"px","value":0.0},"bottomRight":{"unit":"px","value":0.0}}" id="block-yui_3_17_2_1_1691488494850_50798"><div class="sqs-block-content"> <div class="sqs-html-content"> <h2 style="white-space:pre-wrap;">Regulatory Research at CIMT Annual Meeting</h2><p class="" style="white-space:pre-wrap;">In 2023, the CIMT-RRG organized a special session on <strong>trial enrollment for innovatice personalized immunotherapies</strong> as part of the 20th CIMT Annual Meeting. </p><p class="" style="white-space:pre-wrap;"><strong>Chairs:</strong> <strong>Cedrik Britten</strong> (Immatics, Tübingen, Germany), <strong>Stefan Fröhlin</strong>g (German Cancer Research Center DKFZ and NCT Heidelberg, Heidelberg, Germany)</p><p class="" style="white-space:pre-wrap;"><strong>Speakers:</strong> </p><ul data-rte-list="default"><li><p class="" style="white-space:pre-wrap;"><strong>Koustubh Ranade</strong> (Immunocore, Rockville, United States of America)</p><p class="" style="white-space:pre-wrap;"><em>"Tebentafusp-a gp100 directed TCR-CD3 bispecific for the treatment of metastatic uveal melanoma"</em></p></li><li><p class="" style="white-space:pre-wrap;"><strong>Hilke Zander</strong> (Paul-Ehrlich-Institut, Langen, Germany)</p><p class="" style="white-space:pre-wrap;"><em>"Evolving regulatory framework for IVDs and CDxs (IVDR)"</em></p></li><li><p class="" style="white-space:pre-wrap;"> <strong>Miriam Meyer</strong> (Immatics, Tübingen, Germany)</p><p class="" style="white-space:pre-wrap;"><em>“HLA genotyping for T-cell therapy"</em></p></li><li><p class="" style="white-space:pre-wrap;"> <strong>Lisa McShane</strong> (National Institutes of Health, National Cancer Institute, United States of America)<em>"Genomic screening for actionable genomic alterations - experience from NCI precision medicine platform trials"</em></p></li><li><p class="" style="white-space:pre-wrap;"><strong>Stefan Fröhling</strong> (German Cancer Research Center DKFZ and NCT Heidelberg, Heidelberg, Germany)</p></li><li><p class="" style="white-space:pre-wrap;"><em>"RNA sequencing to facilitate patient enrollment into biomarker-guided clinical trias"</em></p></li></ul> </div> </div></div><div class="sqs-block horizontalrule-block sqs-block-horizontalrule" data-block-type="47" id="block-yui_3_17_2_1_1691488494850_89916"><div class="sqs-block-content"><hr /></div></div><div class="sqs-block html-block sqs-block-html" data-block-type="2" data-border-radii="{"topLeft":{"unit":"px","value":0.0},"topRight":{"unit":"px","value":0.0},"bottomLeft":{"unit":"px","value":0.0},"bottomRight":{"unit":"px","value":0.0}}" id="block-yui_3_17_2_1_1691488494850_89977"><div class="sqs-block-content"> <div class="sqs-html-content"> <h2 style="white-space:pre-wrap;">CIMT-RRG Publications</h2><p class="" style="white-space:pre-wrap;">Britten CM, Singh-Jasuja H, Flamion B, Hoos A, Huber C, Kallen K-J, Khleif SN, Kreiter S, Nielsen M, Rammensee H-G, Sahin U, Hinz T, Kalinke U (2013): <a href="http://www.nature.com/nbt/journal/v31/n10/full/nbt.2708.html" target="_blank">The regulatory landscape for actively personalized cancer immunotherapies</a>, Nature Biotechnology 31 (10), 880-882. doi 10.1038/nbt.2708.</p><p class="" style="white-space:pre-wrap;">Hinz T, Kallen K, Britten CM, Flamion B, Granzer U, Hoos A, Huber C, Khleif S, Kreiter S, Rammensee HG, Sahin U, Singh-Jasuja H, Türeci Ö15, Kalinke U. <a href="http://link.springer.com/protocol/10.1007%2F978-1-4939-6481-9_13" target="_blank">The European Regulatory Environment of RNA-Based Vaccines</a>. Methods in Molecular Biology. 2017. Volume 1499. pp 203-222</p> </div> </div></div><div class="sqs-block horizontalrule-block sqs-block-horizontalrule" data-block-type="47" id="block-yui_3_17_2_1_1691488494850_16290"><div class="sqs-block-content"><hr /></div></div><div class="sqs-block html-block sqs-block-html" data-block-type="2" data-border-radii="{"topLeft":{"unit":"px","value":0.0},"topRight":{"unit":"px","value":0.0},"bottomLeft":{"unit":"px","value":0.0},"bottomRight":{"unit":"px","value":0.0}}" id="block-yui_3_17_2_1_1691488494850_16351"><div class="sqs-block-content"> <div class="sqs-html-content"> <h2 style="white-space:pre-wrap;">CIMT-RRG Statutes</h2><p class="" style="white-space:pre-wrap;">Here you can download the <a href="/s/CIMT_RRG_bylaws-t9be.pdf" target="_blank">statutes of the CIMT Regulatory Research Group.</a></p> </div> </div></div><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-yui_3_17_2_1_1534856796124_8849"><div class="sqs-block-content"> </div></div></div><div class="col sqs-col-3 span-3"><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-85bbc0f3c71f896d3311"><div class="sqs-block-content"> </div></div></div></div></div> </section> </main> </div> </div> <footer class="Footer" role="contentinfo" data-controller="FooterBreakpoints"> <div class="Footer-inner clear"> <div class="sqs-layout sqs-grid-12 columns-12 Footer-blocks Footer-blocks--top sqs-alternate-block-style-container" data-layout-label="Footer Top Blocks" data-type="block-field" data-updated-on="1732025648603" id="footerBlocksTop"><div class="row sqs-row"><div class="col sqs-col-12 span-12"><div class="row sqs-row"><div class="col sqs-col-3 span-3"><div class="sqs-block spacer-block sqs-block-spacer sized vsize-1" data-block-type="21" id="block-yui_3_17_2_1_1529586133682_20980"><div class="sqs-block-content"> </div></div></div><div class="col sqs-col-6 span-6"><div class="sqs-block html-block sqs-block-html" data-block-type="2" id="block-yui_3_17_2_1_1530248587920_20494"><div class="sqs-block-content"> <div class="sqs-html-content"> <p style="text-align:center;white-space:pre-wrap;" class=""><a href="/bylaws/#imprint" target="_blank"><strong>IMPRINT</strong></a><strong>  |  </strong><a href="/bylaws"><strong>ASSOCIATION BY-LAWS</strong></a><strong>  |  </strong><a href="/privacy-policy" target="_blank"><strong>PRIVACY POLICY</strong></a><strong> </strong></p> </div> </div></div><div class="sqs-block horizontalrule-block sqs-block-horizontalrule" data-block-type="47" id="block-yui_3_17_2_1_1533652189250_252854"><div class="sqs-block-content"><hr /></div></div><div class="sqs-block button-block sqs-block-button" data-block-type="53" id="block-yui_3_17_2_1_1530248587920_12561"><div class="sqs-block-content"> <div class="sqs-block-button-container sqs-block-button-container--center" data-animation-role="button" data-alignment="center" data-button-size="small" data-button-type="tertiary" > <a href="https://cimt.us9.list-manage.com/subscribe?u=bb4ebd167f23f4ab06a109d92&id=31663cb050" class="sqs-block-button-element--small sqs-button-element--tertiary sqs-block-button-element" target="_blank" > Subscribe to CIMT Newsletter </a> </div> </div></div><div class="sqs-block horizontalrule-block sqs-block-horizontalrule" data-block-type="47" id="block-yui_3_17_2_1_1533652189250_172380"><div class="sqs-block-content"><hr /></div></div><div class="row sqs-row"><div class="col sqs-col-2 span-2"><div class="sqs-block spacer-block sqs-block-spacer" data-aspect-ratio="18.181818181818183" data-block-type="21" id="block-yui_3_17_2_1_1533652189250_235649"><div class="sqs-block-content"> </div></div></div><div class="col sqs-col-0 span-0"></div><div class="col sqs-col-2 span-2"><div class="sqs-block image-block sqs-block-image" data-aspect-ratio="100" data-block-type="5" id="block-yui_3_17_2_1_1530780528134_45591"><div class="sqs-block-content"> <div class=" image-block-outer-wrapper layout-caption-hidden design-layout-inline combination-animation-none individual-animation-none individual-text-animation-none " data-test="image-block-inline-outer-wrapper" > <figure class=" sqs-block-image-figure intrinsic " style="max-width:30px;" > <a class=" sqs-block-image-link " href="https://www.linkedin.com/company/cimt/" target="_blank" > <div class="image-block-wrapper" data-animation-role="image" > <div class="sqs-image-shape-container-element has-aspect-ratio " style=" position: relative; 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