Resource Center :: KORU Medical Systems (KRMD)

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url(https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/432/4628/image.jpg);background-position: 50% 50%;background-repeat: no-repeat;background-size: cover;background-color: #333;"> <div class="container"> <div class="vertical-align"> <div class="wrapper text"> <div class="row"> <div class="col-md-10 col-md-offset-1"> <h1>Resource Hub</h1> </div> </div> <div class="row"> <div class="col-md-8 col-md-offset-2"> </div> </div> </div> </div> </div> </div><nav class="sub-navigation-wrapper"> <div class="sub-navigation affixed"> <div class="container"> <a class="visible-xs visible-sm mobile-sub-nav-trigger collapsed" data-toggle="collapse" data-target="#sub-navigation"> <div class="trigger-container"> <div class="meat"></div> <div class="meat"></div> <div class="meat"></div> </div> Resource Hub </a> <nav class="collapse sb-nav clearfix" id="sub-navigation"> <h3>Resource Hub</h3> <ul> <li class=""> <a href="#row-4728" class="smooth">IVIg vs. SCIg</a> </li> <li class=""> <a href="#row-4729" class="smooth">Hospital vs. Homecare</a> </li> <li class=""> <a href="#row-4730" class="smooth">Optimizing Infusions</a> </li> <li class=""> <a href="#row-3974" class="smooth">IgG Calculator</a> </li> <li class=""> <a href="#row-3971" class="smooth">Training</a> </li> <li class=""> <a href="#row-4425" class="smooth">Resources</a> </li> <li class=""> <a href="#row-4733" class="smooth">News</a> </li> <li class=""> <a href="#row-3992" class="smooth">Partners</a> </li> </ul> </nav> </div> </div> </nav> <div class="visible-sm visible-xs"> <div class="container"> <nav id="tertiary-navigation"> <ul> <li class="sidebar-title"> <h3>Resource Hub</h3> </li> <li class=""> <a href="#row-4728" >IVIg vs. SCIg</a> </li> <li class=""> <a href="#row-4729" >Hospital vs. Homecare</a> </li> <li class=""> <a href="#row-4730" >Optimizing Infusions</a> </li> <li class=""> <a href="#row-3974" >IgG Calculator</a> </li> <li class=""> <a href="#row-3971" >Training</a> </li> <li class=""> <a href="#row-4425" >Resources</a> </li> <li class=""> <a href="#row-4733" >News</a> </li> <li class=""> <a href="#row-3992" >Partners</a> </li> </ul> </nav> </div> </div> <div class="module neutral-bg" id="row-4728"> <div class="container"> <div class="row"> <div class="col-md-8 col-md-offset-2 "> <div class="module-content"> <div class="text-area" data-mh="default"> <div class="wrapper text center"> <h2>IVIg vs. SCIg</h2> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_LearnMore_Icon.png" alt="IVIg vs. SCIg " width="250"></p> <p>Immunoglobulin replacement therapy is generally administered either intravenously (IVIg), or subcutaneously (SCIg). IVIg administration every 3 to 4 weeks and weekly SCIg are regarded as therapeutically equivalent treatments for PIDD and CIDP. The healthcare provider and patient or caregiver should discuss which route of administration is most appropriate for each patient.<sup>1</sup></p> <h3 class="margin-top">IVIg</h3> <p>Intravenous Immunoglobulin (IVIg) infusions are given by a medical professional through an IV cannula in the arm every 3-4 weeks at a specific, prescribed dose. These treatments must be scheduled in advance and are typically done in an infusion suite, physician office, or at home. For patients with poor venous access, subcutaneous immunoglobulin (SCIg) should be the considered route of Ig administration.</p> <p>Some common side effects of IVIg include headache, nausea, fever and chills, flushing, wheezing, vomiting, backache, muscle aches, joint aches, or chest tightness. In most cases, these side effects are related to the rate of the infusion.<sup>2</sup></p> <h3 class="margin-top">SCIg</h3> <p>Subcutaneous Immunoglobulin (SCIg) infusions are given by slowly administering immunoglobulin into fatty tissue (subcutaneous layer) just underneath the skin using an electronic or mechanical infusion pump (such as our Freedom syringe drivers) or by manual push by hand with a syringe. Typical infusion sites are the abdomen, thighs, or outer buttocks. Local site reactions are the most common side effects of SCIg.<sup>2</sup></p> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/Sub-q_sites.png" alt="Sub Q Sites" style="display: block; margin-left: auto; margin-right: auto; max-width: 300px;"></p> <p>The total monthly dose, number of infusion sites (needles) and flow rate tubing is calculated by the pharmacist or other health care provider depending on the body weight, volume and the concentration of the SCIg medication to be infused.</p> <p>SCIg is typically self-administered and can be done at home, thus eliminating the need for monthly hospital or infusion center visits. This allows patients more flexibility and promotes independence.<sup>2</sup><strong> </strong></p> <h3 class="margin-top">Deciding What’s Best for You</h3> <p>If you are new to treatment, make sure you talk to your healthcare provider when deciding which option is best for you. Here is a breakdown of the differences between IVIg and SCIg.<sup>4</sup></p> <p> </p> <table class="ivig-table"> <tbody> <tr> <td> <p><strong>IVIg</strong></p> </td> <td> <p><strong>SCIg</strong></p> </td> </tr> <tr> <td> <p><span>Venous access required</span></p> </td> <td> <p><span>Infuse into fat tissue, not vein</span></p> </td> </tr> <tr> <td> <p><span>Healthcare professional required</span></p> </td> <td> <p><span>Patient self-administered</span></p> </td> </tr> <tr> <td> <p><span>Administer every 3-4 weeks</span></p> </td> <td> <p><span>Administer e.g. weekly</span></p> </td> </tr> <tr> <td> <p><span>Rapid absorption</span></p> </td> <td> <p><span>Gradual absorption (24-72 hours)</span></p> </td> </tr> <tr> <td> <p><span>High peak and low trough levels, increasing risk for fatigue and infections</span><sup>3</sup></p> </td> <td> <p><span>Fewer peaks and troughs due to more consistent IG levels – leading to less infections</span><sup>3</sup></p> </td> </tr> <tr> <td> <p><span>Pre-medication commonly required</span></p> </td> <td> <p><span>Pre-medication often not required</span></p> </td> </tr> </tbody> </table> <p> </p> <p style="text-align: center;"><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_LandingPage_SCIg_Chart.png" alt="SCIg_Chart" style="padding-right: 4px; max-width: 49%;"><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_LandingPage_Subcutaneous_Chart.png" alt="Subcutaneous_Chart." style="padding-left: 4px; max-width: 49%;"></p> <p><strong>  </strong></p> <p style="text-align: left;"><small>References:</small></p> <ol class="references-list"> <li>Institute of Allergy and Infectious Diseases. <em>Primary immune deficiency diseases (PIDDs</em>). <a href="http://www.niaid.nih.gov/diseases-conditions/primary-immune-deficiency-diseases-PIDDs" target="_blank" rel="noopener">niaid.nih.gov/diseases-conditions/primary-immune-deficiency-diseases-PIDDs</a>. Accessed Aug 19, 2020</li> <li>Immune Deficiency Foundation. <em>IDF Guide to IG Therapy, 6th Edition</em>. 2018. <a href="http://www.primaryimmune.org" target="_blank" rel="noopener">primaryimmune.org</a></li> <li>Shrestha et al. <em>Impact of IVIG vs. SCIG on IgG trough level and infection incidence in primary immunodeficiency diseases: A systematic review and meta-analysis of clinical studies</em>. World Allergy Organization Journal (2019) 12: 10068</li> <li>Shapiro R. <em>Subcutaneous Immunoglobulin.</em> Immunol Allergy Clin NA. 2020. In press.</li> </ol> <p><strong> </strong></p> <h3 class="margin-top">Related Publications</h3> <p><span><a href="https://pubmed.ncbi.nlm.nih.gov/15207776/" target="_blank" rel="noopener">Subcutaneous immunoglobulin replacement in primary immunodeficiencies</a></span></p> <p><span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792336/" target="_blank" rel="noopener">Quantitative Evidence of Wear-Off Effect at the End of the Intravenous IgG (IVIG) Dosing Cycle in Primary Immunodeficiency</a></span></p> <p><span><a href="https://pubmed.ncbi.nlm.nih.gov/31641401/" target="_blank" rel="noopener">Impact of IVIG vs. SCIG on IgG Trough Level and Infection Incidence in Primary Immunodeficiency Diseases: A Systematic Review and Meta-Analysis of Clinical Studies</a></span></p> <p><span><a href="https://d1io3yog0oux5.cloudfront.net/_75126ec78c19be413a5a80ecad6fd486/rmsmedicalproducts/db/509/4073/pdf/f60_po_sci_scigcasestudy_esid_03-1103va.pdf" target="_blank" rel="noopener">Poster: Patient IVIg to SCIg Case Study</a></span></p> </div> </div> </div> </div> </div> </div> </div> <div class="module " id="row-4729"> <div class="container"> <div class="row"> <div class="col-md-8 col-md-offset-2 "> <div class="module-content"> <div class="text-area" data-mh="default"> <div class="wrapper text center"> <h2>Hospital vs. Homecare</h2> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_Homecare_Icon.png" alt="Treatment Options" width="250"></p> <p>Hospitals save lives while home health care improves lives. Homecare increases patient function and enhances an independent lifestyle. Most people need hospitalization at least once in their lives, but a growing number of individuals are choosing long-term treatment in the comfort of their own homes. Patients report a variety of reasons to opt for homecare, including convenience, care, confidence, and cost.<sup>1,2</sup></p> <p>With home health care, patients can avoid the inconvenience of a hospital stay and reduce associated expenditures associated with hospitalization. Benefits of outpatient clinic or at home-based care include avoiding hospital admissions, reduced length of hospital stay, less healthcare associated infections, and the ability to return to work faster and to resume daily activities of living.<sup>1-3</sup></p> <p>According to the US Centers for Disease Control, 1 in 31 patients in the hospital get healthcare associated infections.<sup>4</sup> Medical advances have brought lifesaving care to patients in need, yet many of these advances come with a risk of healthcare-associated conditions, including infections. These infections could lead to significant patient illnesses and deaths (morbidity and mortality); prolong the duration of hospital stays; and require additional testing and therapeutic involvement, which generate added costs.<sup>5</sup></p> <p>Homecare is especially practical for those with chronic illnesses. If you are immunocompromised, it is a particularly important time to stay safe, healthy, and reduce your exposure to germs. Learn how our Freedom Infusion System delivers peace of mind in this brief overview:<br><a href="https://www.korumedical.com/peace-of-mind" target="_blank" rel="noopener">Subcutaneous Infusion: Your Peace of Mind During an Uncertain Time</a></p> <p style="text-align: left;"><small>References:</small></p> <ol class="references-list"> <li>Polinski et al. <em>Home infusion: Safe, clinically effective, patient preferred, and cost saving</em>. Healthcare. 2017; 5:68-80.</li> <li><em>Home Infusion: Benefits and Barriers</em>. <span><a href="http://www.carecentrix.com" target="_blank" rel="noopener">www.carecentrix.com</a></span> Accessed Aug 19, 2020</li> <li><em>Infusion therapy: No place like home</em>. <a href="https://www.optum.com/business/health-insights/infusion-therapy.html" target="_blank" rel="noopener">https://www.optum.com/business/health-insights/infusion-therapy.html</a> Accessed Aug 19, 2020</li> <li><em> </em>Magill S et al. <em>Changes in Prevalence of Health Care-Associated Infections in U.S. Hospitals. </em>N Engl J Med 2018;379(18):1732-1744.</li> <li><em> </em>Premier Safety Institute. <em>Healthcare Associated Infections</em>. <span><a href="https://www.premiersafetyinstitute.org/safety-topics-az/healthcare-associated-infections-hais/hai/" target="_blank" rel="noopener">https://www.premiersafetyinstitute.org/safety-topics-az/healthcare-associated-infections-hais/hai/</a> </span>Accessed June 30, 2020</li> </ol> <p><strong> </strong></p> <h3><strong>Related Publications</strong></h3> <p><a href="https://pubmed.ncbi.nlm.nih.gov/30380384/" target="_blank" rel="noopener">Changes in Prevalence of Health Care-Associated Infections in U.S. Hospitals</a></p> <p><span><a href="https://link.springer.com/article/10.1007/s11606-018-4307-z#Sec16" target="_blank" rel="noopener">Hospital-Level Care at Home for Acutely Ill Adults: a Pilot Randomized Controlled Trial</a></span></p> <p><span><a href="https://pubmed.ncbi.nlm.nih.gov/31318516/" target="_blank" rel="noopener">Managing Cost of Care and Healthcare Utilization in Patients Using Immunoglobulin Agents</a></span></p> <p><span> </span></p> <h3>Resources</h3> <p><a href="https://www.cdc.gov/hai/index.html" target="_blank" rel="noopener">CDC Healthcare-associated Infections</a></p> </div> </div> </div> </div> </div> </div> </div> <div class="module neutral-bg" id="row-4730"> <div class="container"> <div class="row"> <div class="col-md-8 col-md-offset-2 "> <div class="module-content"> <div class="text-area" data-mh="default"> <div class="wrapper text center"> <h2>Optimizing Infusions</h2> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_Infusions_Icon.png" alt="Infusions" width="250"></p> <p>Several variables involved with SCIg allow optimization of the infusion experience for patients. Some of these variables include number of needle-sticks, infusion sites, volume infused/site, needle length and pump type.</p> <p>SCIg is delivered using a small needle attached to tubing and a syringe that is placed in a mechanical pump or an electronic programmable pump. Both pumps are portable. Several needle and tubing sizes are available for mechanical pumps and troubleshooting problems with SCIg often involves reviewing that the equipment being used, such as needle sets, tubing, and pump are appropriate for the individual receiving the therapy.</p> <p> </p> <h3><strong>Choosing an Infusion Device</strong></h3> <p>There are different options when it comes to infusion pumps and devices, the main two being electronic pumps (constant flow systems) and mechanical pumps (constant pressure systems).</p> <table class="ivig-table"> <tbody> <tr> <td width="50%"> <p><strong>Constant Flow Systems</strong></p> </td> <td width="50%"> <p><strong>Constant Pressure Systems (KORU Freedom systems)</strong></p> </td> </tr> <tr> <td> <p>Electronic devices</p> </td> <td> <p>Mechanical devices</p> </td> </tr> <tr> <td> <p>Programmed to a specific flow rate</p> </td> <td> <p>No programming</p> </td> </tr> <tr> <td> <p>Respond to tissue saturation by increasing pressure</p> </td> <td> <p>Respond to tissue saturation by slowing down the infusion to maintain the same safe pressure throughout the infusion</p> </td> </tr> <tr class="image-row"> <td><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/Constant+Flow.gif" alt="Constant Flow" style="max-width: 100%;"></td> <td><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/Constant+pressure.gif" alt="Constant Pressure" style="max-width: 100%;"></td> </tr> </tbody> </table> <p> </p> <h3 class="margin-top">Dynamic Equilibrium</h3> <p>Our Freedom infusion systems are designed to function based on how well the patient's body absorbs medication. This benefit, known as DynEQ® (Dynamic Equilibrium), means that the system responds to building pressure in the subcutaneous tissue during SCIg infusions, by slowing down the infusion to ensure a balanced infusion.</p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4081/pdf/trs_po2_infusiondevices_igns2016_va_lr.pdf" target="_blank" rel="noopener">Selecting the Right Infusion Device</a></p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4082/pdf/trs_po3_bestinfsites_igns2016_va_lr.pdf" target="_blank" rel="noopener">Secrets to Finding the Best Infusion Sites</a></p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4072/pdf/f60_po_sci_infusionpumpdesignvert_03-1060vb.pdf" target="_blank" rel="noopener">Infusion Pump Design for SCIg</a></p> <h3 class="margin-top">Needle Design</h3> <p>If the patient is having local site reactions, the healthcare provider can consider changing the needle type before changing the medication. Compared with tricuspid needles, lancet-type needles may cause more coring of the skin, resulting in increased bleeding and tissue trauma.<sup> </sup> The tricuspid needle tip design of HigH-Flo Subcutaneous Safety Needle Sets™ minimizes damage and scarring, resulting in less site reactions.<sup>1</sup></p> <p style="text-align: center;"><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/tricuspid-lancet-needles.png" alt="Needle Design" width="320px"></p> <p><sup> </sup><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4086/pdf/ancillary-supplies_ins-2012_final.pdf" target="_blank" rel="noopener">Importance of Ancillary Supplies for Subcutaneous Immunoglobulin Infusion</a></p> <h3 class="margin-top">Troubleshooting SCIg Site Reactions</h3> <p>When patients are trained correctly, site reactions could become a rare occurrence. When site reactions do occur, patients can experience redness, irritation, drug leakage, itching, pain, and discomfort.</p> <h4><br>Flow Rate</h4> <p>Selecting the correct flow rate tubing is important when starting SCIg therapy. It may be trial and error to find which flow rate works best for you/your patients. For patients who experience site reactions, a slower flow rate tubing set is recommended.</p> <p>The Freedom infusion systems slow down the infusion automatically if the resistance in the tissue increases. However, by choosing the slower flow rate, it is possible to minimize or prevent the tissue saturation.</p> <h4><strong><br>Needle Length</strong></h4> <p>Choosing the correct needle length is very important when getting started on SCIg. Every ‘body’ is different but generally: infants use 4 mm, children (up to age 9) and patient sites with extremely low body fat use 6 mm, over age 9 and adults use 9 mm and/or 12 mm, and very large adults use 14 mm.<sup>1</sup></p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4078/pdf/trs_po_drugleakage_esid2016_va_lr.pdf" target="_blank" rel="noopener">Incidence of Drug Leakage When Giving SCIg and fSCIg Treatments</a></p> <p style="text-align: center;"><strong><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU+Needle+Length.png" alt="Dry Priming" style="max-width: 300px;"></strong></p> <p><b>Short needles can cause:<br><br></b>Leaking from the sites<br><br>Bumps around the sites<br><br>Needle site discomfort<br><br>Extended infusion times<strong> </strong></p> <h4><strong><br>Dry Priming</strong></h4> <p>It is recommended to insert the needles dry, as drug leaking needles can cause irritation to the site.<sup>3</sup></p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_75126ec78c19be413a5a80ecad6fd486/rmsmedicalproducts/db/509/4085/pdf/wetdry-needles-diplomat.pdf" target="_blank" rel="noopener">Reducing Incidences of Local Infusion Site Reactions</a></p> <h4><br>Drug Volume</h4> <p>Volume per site is a key factor to consider, especially because every body-type is different. Patients with more adipose/fatty tissue will be able to accept Ig easier. Thinner patients may experience longer infusion times and more substantial site reactions. The volume per site needs to be weighed against the subcutaneous tissue available. Many times, spreading the volume out to more sites will help keep volume per site low and can eliminate site reactions.<sup>2</sup></p> <h4><strong><br>Site Location</strong></h4> <p>The abdomen is the most common place to infuse, but the upper buttocks/side of upper hips, the outer side of the thighs, and the back of the upper arms are also used. It is important that the site(s) chosen has a good amount of subcutaneous tissue. Some medications require that sites be 2+ inches (5 cm) apart, and that the needles are inserted at a 90° angle. If and how to rotate infusion sites should be a subject for discussion between the patient and healthcare provider. You may achieve better results by periodically returning to sites that have worked well in the past.<sup>3</sup></p> <p style="text-align: center;"><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/stomach-subq.jpg" alt="Stomach" style="display: inline-block; height: 210px; padding-right: 12px;"><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/needle-insertion_1.jpg" alt="Needle Insertion" style="display: inline-block; height: 210px; padding-left: 12px;"></p> <h4>Adhesive Dressing</h4> <p>The dressing used can make a difference. 3M Tegaderm™ dressing, provided with every HIgH-Flo subcutaneous needle set, provides gentle adhesion without building to excessive levels over time, for easy removal.<sup>4</sup> To release the adhesive, pull and stretch it out horizontally parallel to the skin. Any redness to skin should be only temporary.</p> <p style="text-align: left;"><small>References:</small></p> <ol class="references-list"> <li>Duff et al<em>. Importance of Ancillary Supplies for Subcutaneous Immunoglobulin Infusion</em>. J Infus Nurs. 2013; 36:384-390</li> <li>Younger ME et al. <em>Nursing Guidelines for Administration of Immunoglobulin Replacement Therapy.</em> J Inf Nurs. 2013; 36:58-64</li> <li>Duff et al. <em>Nuts and Bolts of Subcutaneous Therapy. </em>Immunol Allergy Clin N Am 2020; 40:527-537</li> <li>3M,<em> 3M™ Tegaderm™ Transparent Film Dressings Product Profile</em>, <a href="https://multimedia.3m.com/mws/media/447983O/tegaderm-transparent-film-dressing-brochure.pdf" target="_blank" rel="noopener">https://multimedia.3m.com/mws/media/447983O/tegaderm-transparent-film-dressing-brochure.pdf</a> Accessed Aug 19, 2020.</li> </ol> <p><strong> </strong></p> <h3 class="margin-top">Related Publications</h3> <p><a href="https://pubmed.ncbi.nlm.nih.gov/24202117/" target="_blank" rel="noopener">Importance of ancillary supplies for subcutaneous immunoglobulin infusion: management of the local infusion site</a></p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/23271153/" target="_blank" rel="noopener">Nursing guidelines for administration of immunoglobulin replacement therapy</a></p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/32654697/" target="_blank" rel="noopener">Nuts and Bolts of Subcutaneous Therapy</a></p> <p><a href="https://d1io3yog0oux5.cloudfront.net/_38039eb576b5b1fb7e00db04d3d415cc/rmsmedicalproducts/db/509/4516/pdf/TRS_PO_Super26_11x17_IgNS2019_vA.pdf" target="_blank" rel="noopener">Quality Improvement Study to Evaluate Patient-Centered Outcomes and Infusion Parameters Using the HIgH-Flo Super26</a></p> </div> </div> </div> </div> </div> </div> </div> <div class="module " id="row-3974"> <div class="container"> <div class="row"> <div class="col-md-8 col-md-offset-2 "> <div class="module-content"> <div class="text-area" data-mh="default"> <div class="wrapper text center"> <h2>Freedom Flow Rate Calculator</h2> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/system-puzzle.png" caption="false" width="360" height="365" alt="Freedom Flow Rate"></p> <p><strong>Determine the tubing & needle combination for desired flow rate/infusion time<br></strong>The Freedom Flow Rate Calculator is provided as a guide to assist healthcare providers in selecting the optimal Precision Flow Rate Tubing set and HIgH-Flo Subcutaneous Safety Needle Set for use with Ig in the FREEDOM60® and FreedomEdge® Syringe Infusion Systems.</p> <p><strong>Calculate in a few simple steps:</strong></p> <p>1. Choose your device<br>2. Choose the medication & input the dose<br>3. Choose flow rate tubing & needle set<br>4. Make sure that the flow rate per site and total infusion <br>time are within the range of medication prescribing information.</p> <p><small>*The Freedom Flow Rate Calculator does not dose, nor is it intended to override or substitute for the directions of the prescribing medical professional. It is also the responsibility of the medical professional to have a complete understanding of the IgG drug’s package insert before use.</small></p> <p><a href="https://korucalculator.com/" class="btn" target="_blank" rel="noopener">Calculate Now</a></p> <p><a href="/products/antibiotic-home-infusion-solutions" class="btn">Infusing Antibiotics?</a></p> <p><small><a href="/tubing-calculator-terms-and-conditions" target="_blank" rel="noopener">Click here</a> to review Terms and Conditions for the FREEDOM Flow Rate Calculator</small></p> <p><small><a href="https://s3.amazonaws.com/content.stockpr.com/korumedical/files/pages/rmsmedicalproducts/db/481/description/KORU+FREEDOM+Flow+Rate+Calculator+Privacy+Policy.pdf" target="_blank" rel="noopener">Click here</a> to review the Privacy Policy for the FREEDOM Flow Rate Calculator</small></p> </div> </div> </div> </div> </div> </div> </div><section id="row-3971" class="module module-upcoming-training-sessions overlay primary-color-overlay dark" style="background-image: url(https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/481/3971/background_image.jpg);background-position: 50% 50%;background-repeat: no-repeat;background-size: cover;background-color: #333;"> <div class="container"> <header class="center"> <div class="row"> <div class="col-sm-8 col-sm-offset-2"> <h2>Online Training</h2> <p>KORU is here to help! We offer regular online training sessions for nurses, healthcare providers, and pharmacists. In these sessions, we will provide an overview of the Freedom Integrated Infusion system and will allow all attendees the opportunity to ask questions.</p> <p><span>To schedule personal training sessions, please email </span><a href="mailto:nursing@korumedical.com" rel="noopener noreferrer" target="_blank" heap-ignore="true" class="_ar_hide_" _ar_hide_="width:170px;height:16px;margin:0px;position:static;display:inline-block;">nursing@korumedical.com</a></p> </div> </div> </header> <div class="flex-row"> <article class="content-box dark" data-mh="training-session-content-box"> <h4>SCIg Overview, Infusion Training and Optimization</h4> <time class="date" datetime="2024-12-12T14:00:00">Dec 12, 2024 • 1:00 pm - 2:00 pm EST</time> <p>This comprehensive session provides an in-depth demonstration of how to use Freedom Infusion System in addition to providing background into the patients current supported and opportunities for optimization.</p> <p>Ideal for Specialty Pharmacists, Clinical Teams and other Healthcare Professionals who are new to SCIg or Freedom, or are looking for a refresher training with the new, redesigned infusion pumps and expanded syringe compatibility, including two prefilled syringe options!</p> <a href="https://korumedical.zoom.us/webinar/register/WN_5xr__0TBSEC4xTytsawiGw" class="btn" target="_blank">Register for Training</a> </article> <article class="content-box dark" data-mh="training-session-content-box"> <h4>SCIg Overview, Infusion Training and Optimization</h4> <time class="date" datetime="9200-11-23T17:36:44">Jan 9, 2025 • 1:00 pm - 2:00 pm EST</time> <p>This comprehensive session provides an in-depth demonstration of how to use Freedom Infusion System in addition to providing background into the patients current supported and opportunities for optimization.</p> <p>Ideal for Specialty Pharmacists, Clinical Teams and other Healthcare Professionals who are new to SCIg or Freedom, or are looking for a refresher training with the new, redesigned infusion pumps and expanded syringe compatibility, including two prefilled syringe options!</p> <a href="https://korumedical.zoom.us/webinar/register/WN_5xr__0TBSEC4xTytsawiGw" class="btn" target="_blank">Register for Training</a> </article> <article class="content-box dark" data-mh="training-session-content-box"> <h4>Freedom Infusion System + Prefilled Syringes Training</h4> <time class="date" datetime="2025-01-23T12:00:00">Jan 23, 2025 • 11:30 am - 12:00 pm EST</time> <p>Discover how combining the benefits and ease of use of the Freedom systems with the reduced drug preparation tasks of prefilled syringes can optimize the infusion experience for your patients.</p> <p>Ideal for Specialty Pharmacists, Clinical Teams and other Healthcare Professionals interested in learning about the new, redesigned infusion pumps and the enhanced compatibility with prefilled syringes.</p> <a href="https://korumedical.zoom.us/webinar/register/WN_5GM1KpK-SamJYlYVo6hJ6g" class="btn" target="_blank">Register for Training</a> </article> </div> </div> </section><section class="module module-product-videos " id="row-3976"> <div class="container"> <header> <h2>Step-by-Step Training Videos</h2> </header> <div class="flex-row"> <figure> <a href="//youtube.com/embed/jWeW3M4hnrA?autoplay=true" class="fancybox fancybox.iframe video-link" style="background-image: url(https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/508/3977/image.jpg);background-position: 50% 50%;background-repeat: no-repeat;background-size: cover;background-color: #333;"> <span class="sr-only">Watch video on YouTube</span> </a> <figcaption> <h4>FREEDOM60® Step-by-Step SCIg Training Video</h4> </figcaption> </figure> <figure> <a href="//youtube.com/embed/R4J2giR3n3g?autoplay=true" class="fancybox fancybox.iframe video-link" style="background-image: url(https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/508/3975/image.jpg);background-position: 50% 50%;background-repeat: no-repeat;background-size: cover;background-color: #333;"> <span class="sr-only">Watch video on YouTube</span> </a> <figcaption> <h4>FreedomEdge® Step-by-Step SCIg Training Video</h4> </figcaption> </figure> </div> <div class="mod-prouct-videos-btn"> <a href="https://www.korumedical.com/patients/training-resources#freedom60" class="btn"> See All Step-by-Step Videos</a> </div> </div> </section><section class="module module-patient-resources " id="row-4425"> <header> <h2>Resources</h2> <p><img src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/pages/rmsmedicalproducts/db/481/description/KORU_Download_Icon.png" alt="Download Icon" width="250"></p> </header> <div class="container"> <div class="row"> <div class="col-sm-8 col-sm-offset-2"> <div class="module-content"> <figure class="partner-item"> <figcaption> <h3>Freedom Infusion System Instructions For Use</h3> <p>Always refer to your product Instructions For Use when starting Ig therapy with the Freedom system. If you have any questions, please contact your healthcare provider.</p>  <p><a href="https://www.korumedical.com/IFUs">Instructions for Use</a></p> </figcaption> </figure> <figure class="partner-item"> <figcaption> <h3>IDF Resource Center</h3> <p>The Immune Deficiency Foundation's online Resource Center has an abundance of materials and tools to help patients and family members of those with Primary Immunodeficiencies stay informed.</p> <a href="//www.primaryimmune.org/resource-center" target="_blank">www.primaryimmune.org/resource-center</a> </figcaption> </figure> <figure class="partner-item"> <figcaption> <h3>IG Living</h3> <p>Join the immune globulin community with access to IG Living magazine, advocacy groups, expert opinions, and patients with rare diseases.</p> <a href="//www.igliving.com" target="_blank">www.igliving.com</a> </figcaption> </figure> <figure class="partner-item"> <figcaption> <h3>Jeffrey Modell Foundation</h3> <p>The Jeffrey Modell Foundation directs efforts toward early diagnosis, meaningful treatments, equal access to care, and ultimately, a cure for Primary Immunodeficiency.</p> <a href="//www.info4pi.org" target="_blank">www.info4pi.org</a> </figcaption> </figure> </div> </div> </div> </div> </section> <div class="module " id="row-4733"> <div class="container"> <div class="row"> <div class="col-md-8 col-md-offset-2 "> <div class="module-content"> <div class="text-area" data-mh="default"> <div class="wrapper text center"> <h2>New from KORU</h2> <div style="position: relative; padding-bottom: 56.25%; padding-top: 35px; height: 0; overflow: hidden;"><iframe allowfullscreen="true" webkitallowfullscreen="true" mozallowfullscreen="true" style="position: absolute; top: 0; left: 0; width: 100%; height: 100%;" src="https://d1io3yog0oux5.cloudfront.net/rmsmedicalproducts/files/newsletters/newsletter-q2-2022/index.html" frameborder="0"></iframe></div> </div> </div> </div> </div> </div> </div> </div> <div class="module module-latest-news overlay--dark background overlay dark" style="background-image: url(https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/481/3969/background_image.jpg);background-position: 50% 50%;background-repeat: no-repeat;background-size: cover;background-color: #333;" id="row-3969"> <div class="container"> <div class="row"> <div class="col-lg-8 col-lg-offset-2 col-md-10 col-md-offset-1"> <div class="module-content"> <div class="vertical-align" data-mh="latest-news-list-default"> <div class="wrapper text center"> <h2>Latest Updates</h2> </div> </div> </div> </div> </div> <div class="news-listing"> <div class="row"> <div class="col-sm-4 news-col"> <article class="media" data-mh="latest-news-list"> <p class="date"><time datetime="2024-11-13T16:05:00">Nov 13, 2024 4:05pm EST</time></p> <h3 class="media-heading"><a href="https://www.korumedical.com/investors/news-events/press-releases/detail/168/koru-medical-systems-inc-announces-2024-q3-financial">KORU Medical Systems, Inc. Announces 2024 Q3 Financial Results, Third Consecutive Quarter of Double-Digit Growth; Raises Full Year 2024 Guidance</a></h3> </article> </div> <div class="col-sm-4 news-col"> <article class="media" data-mh="latest-news-list"> <p class="date"><time datetime="2024-11-06T16:05:00">Nov 6, 2024 4:05pm EST</time></p> <h3 class="media-heading"><a href="https://www.korumedical.com/investors/news-events/press-releases/detail/167/koru-medical-systems-to-participate-in-upcoming-investor">KORU Medical Systems to Participate in Upcoming Investor Conferences</a></h3> </article> </div> <div class="col-sm-4 news-col"> <article class="media" data-mh="latest-news-list"> <p class="date"><time datetime="2024-10-31T16:03:00">Oct 31, 2024 4:03pm EDT</time></p> <h3 class="media-heading"><a href="https://www.korumedical.com/investors/news-events/press-releases/detail/166/koru-medical-systems-presents-data-at-partnership">KORU Medical Systems Presents Data at Partnership Opportunities in Drug Delivery (PODD) Conference Demonstrating Nursing Preference for Use of KORU FreedomEdge® Infusion System over Manual Syringe Administration for Subcutaneous Oncology Infusion</a></h3> </article> </div> </div> </div> <div class="center"> <a href="https://www.korumedical.com/investors/news-events/press-releases" class="btn">View all news</a> </div> </div> </div><section class="module module-partner-listing neutral-bg" id="row-3992"> <header> <h2>Partners & Sponsors</h2> <p>As the leading manufacturer of Syringe Infusion Systems and Medical Suction devices, we are proud to partner with and support the leading organizations within our industries to provide valuable information to our customers.</p> </header> <div class="container"> <div class="row"> <div class="col-sm-8 col-sm-offset-2"> <div class="module-content"> <figure class="partner-item"> <div class="image-wrapper"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/511/4091/image.png" alt="" /> </div> <figcaption> <p>The Immune Deficiency Foundation (IDF), founded in 1980, is the national non-profit patient organization dedicated to improving the diagnosis, treatment and quality of life of persons with PI through advocacy, education and research. IDF provides accurate and timely information for patients and families living with PI and offers valuable resources.</p> <a href="//www.primaryimmune.org" target="_blank">www.primaryimmune.org</a> </figure> <figure class="partner-item"> <div class="image-wrapper"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/511/4092/image.png" alt="" /> </div> <figcaption> <p>NHIA is a trade association that represents and advances the interests of organizations that provide infusion and specialty pharmacy products and services to the entire spectrum of home-based patients. The website is available to serve its members, the infusion patient, physicians and others interested in learning about the infusion field.</p> <a href="//www.nhia.org" target="_blank">www.nhia.org</a> </figure> <figure class="partner-item"> <div class="image-wrapper"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/511/4093/image.png" alt="" /> </div> <figcaption> <p>The Infusion Nurses Society (INS), is a national nonprofit organization representing infusion nurses and all other clinicians who practice infusion therapy. Since 1973, INS has continued its commitment to bringing innovative new resources and learning opportunities to the wide range of healthcare professionals involved in the specialty practice of infusion therapy.</p> <a href="//www.ins1.org" target="_blank">www.ins1.org</a> </figure> <figure class="partner-item"> <div class="image-wrapper"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/511/4393/image.png" alt="" /> </div> <figcaption> <p>The GBS/CIDP Foundation International is working for a future when no one with Guillain-Barre syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and related syndromes such as multifocal motor neuropathy (MMN) suffers alone and that everyone has access to the right diagnosis and the right treatment, right away.</p> <a href="//www.gbs-cidp.org" target="_blank">www.gbs-cidp.org</a> </figure> <figure class="partner-item"> <div class="image-wrapper"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/db/511/4694/image.png" alt="" /> </div> <figcaption> <p>The Immunoglobulin National Society (IgNS) is a professional organization dedicated to the advancement of Ig therapy practice, across clinical indications and areas of practice with focus on promoting patient-centric initiatives.</p> <a href="//www.ig-ns.org" target="_blank">www.ig-ns.org</a> </figure> </div> </div> </div> </section><footer id="footer"> <div class="footer-main"> <div class="container"> <div class="row"> <div class="col-sm-12 col-md-4"> <div class="footer-header"> <div class="footer-logo"> <a href="/"> <img src="https://d1io3yog0oux5.cloudfront.net/_0eb9eb7c5a5cc42bae42cbb4821f1b24/korumedical/files/theme/images/footer-logo-white@1x.svg" width="199" height="56" alt="KORU Medical Systems"> </a> </div> <p>KORU Medical Systems<br> 100 Corporate Drive<br> Mahwah, NJ 07430 <br>USA</p> </div> </div> <div class="col-sm-4 col-md-3 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