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src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27760%27%20height=%27740%27/%3e"/></span><img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img srcSet="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_1520x1480_crop_center-center_none%2Fchristian-bowen-TOKVE7PNwAc-unsplash.jpg&w=828&q=75 1x, /_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_1520x1480_crop_center-center_none%2Fchristian-bowen-TOKVE7PNwAc-unsplash.jpg&w=1920&q=75 2x" src="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_1520x1480_crop_center-center_none%2Fchristian-bowen-TOKVE7PNwAc-unsplash.jpg&w=1920&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span></figure><div class="style_text__aOkrO"><div><div class="style_kicker__Xv5sP">About</div><h1>Our Story</h1><p>Understanding how and why some people鈥檚 lungs are unable to defend themselves against infection has been at the heart of the Synairgen story.</p></div></div></div></section></header><header id="" class="style_wrap__qjPVe style_heading__tBKDb"><div class="style_container__sgRJ7 "><h2>Who are Synairgen?</h2></div></header><figure id="" class="style_wrap__qjPVe "><div class="style_container__sgRJ7 "><div class="style_video__sUzrG style_video__cRCn6"><div><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%271160%27%20height=%27652.5%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_2320x1305_crop_center-center_none%2FSynairgen-film-thumbnail.jpg&w=1200&q=75 1x, /_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_2320x1305_crop_center-center_none%2FSynairgen-film-thumbnail.jpg&w=3840&q=75 2x" src="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_2320x1305_crop_center-center_none%2FSynairgen-film-thumbnail.jpg&w=3840&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span><div class="style_play__U91MU"><span></span></div></div></div></div></figure><section id="" class="style_wrap__qjPVe style_block__1WxMy"><div class="style_container__sgRJ7 style_text__mN2n9"><div class="style_prose__woZCM "><p>In the 1970s, British immunophysician Professor Sir Stephen Holgate, began investigating how respiratory viruses can cause serious illness, with the aim of translating these insights into effective clinical treatments. Joined by fellow University of Southampton professors Donna Davies and Ratko Djukanovic, the three formed Synairgen in 2003 with the sole aim of bringing these advances to patients.</p> <p>Pioneers of using ex vivo models, which use cells collected from patients with respiratory disease, Synairgen was able to make major advances in the understanding of the defence mechanisms of the human lung. This ground-breaking research showed that interferon beta (IFN-尾) was an essential component in an effectively functioning respiratory defence system, and any deficiencies in this naturally occurring protein were likely to lead to serious illness and even death. </p> <p>Synairgen has developed SNG001, an inhaled formulation of IFN-尾 designed to directly target the lungs, the primary site of many viral lung infections.<br/></p> <p>SNG001 has been tested in several clinical studies in both out-patient and hospital settings and was found to boost lung antiviral responses, accelerate viral clearance from the lungs, be well tolerated and show potential for clinical benefit in patients with various respiratory infections.</p></div></div></section><section id="" class="style_wrap__qjPVe style_gallery__ViR5I"><div class="style_container__sgRJ7 style_inner__92GOW style_grid__piEkS"><header><h3>Our Founders</h3></header><figure class="style_img1-3__tuqSz"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27458%27%20height=%27578%27/%3e"/></span><img alt="Professor Sir Stephen Holgate" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Professor Sir Stephen Holgate" srcSet="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0147.jpg&w=640&q=75 1x, /_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0147.jpg&w=1080&q=75 2x" src="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0147.jpg&w=1080&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span><figcaption>Professor Sir Stephen Holgate is a co-founder of Synairgen and was appointed a non-executive director in June 2003. He is the Medical Research Council Clinical Professor of Immunopharmacology at the University of Southampton.</figcaption></figure><figure class="style_img2-3__4NVrR"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27458%27%20height=%27578%27/%3e"/></span><img alt="Professor Ratko Djukanovic" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Professor Ratko Djukanovic" srcSet="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0087.jpg&w=640&q=75 1x, /_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0087.jpg&w=1080&q=75 2x" src="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0087.jpg&w=1080&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span><figcaption>Professor Ratko Djukanovic is a co-founder of Synairgen and Professor of Medicine at University of Southampton.</figcaption></figure><figure class="style_img3-3__4miO4"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27458%27%20height=%27578%27/%3e"/></span><img alt="Professor Donna Davies" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Professor Donna Davies" srcSet="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0175.jpg&w=640&q=75 1x, /_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0175.jpg&w=1080&q=75 2x" src="/_next/image?url=https%3A%2F%2Fsynairgen.ams3.digitaloceanspaces.com%2F_912x1156_crop_center-center_none%2FDSF0175.jpg&w=1080&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span><figcaption>A co-founder of Synairgen, Professor Donna Davies is Professor of Respiratory Cell and Molecular Biology, within Medicine at the University of Southampton.</figcaption></figure></div></section><section id="" class="style_wrap__qjPVe style_cta__PXo_4 style_centered__QMkxX"><div class="style_container__sgRJ7 "><div class="style_blobs__K_iOE style_blobs__ufu8b"><span class="style_blob__1JQDk"></span><span class="style_blob__1JQDk"></span><span class="style_blob__1JQDk"></span></div><div class="style_content___znDc"><h2>Interferon Beta</h2><div class="style_prose__woZCM "><p>Discover how IFN-尾 has been shown in the laboratory to protect cells from infection from a wide variety of seasonal respiratory and pandemic viruses including RSV, rhinovirus, various influenza strains including H5N1, and MERS-CoV. </p></div><footer class="style_btnGroup___hsE2 "><a rel="" class="style_btn__g6gfm " href="/science">Learn more about our science</a></footer></div></div></section><footer id="" class="style_wrap__qjPVe style_footer__IKWh6"><div 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