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</div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目录" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" 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class="vector-toc-list"> </ul> </li> <li id="toc-參見" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參見"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>參見</span> </div> </a> <ul id="toc-參見-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參考文獻" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參考文獻"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>參考文獻</span> </div> </a> <ul id="toc-參考文獻-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部連結" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部連結"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>外部連結</span> </div> </a> <ul id="toc-外部連結-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">阿莫待奎</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。20种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-20" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">20种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A3%D9%85%D9%88%D9%8A%D8%A7%D9%83%D9%88%D9%8A%D9%86" title="أموياكوين – 阿拉伯语" lang="ar" hreflang="ar" data-title="أموياكوين" data-language-autonym="العربية" data-language-local-name="阿拉伯语" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A2%D9%85%D9%88%D8%AF%DB%8C%D8%A7%DA%A9%DB%8C%D9%86" title="آمودیاکین – South Azerbaijani" lang="azb" hreflang="azb" data-title="آمودیاکین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Amodiaquina" title="Amodiaquina – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Amodiaquina" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Amodiaquin" title="Amodiaquin – 德语" lang="de" hreflang="de" data-title="Amodiaquin" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Amodiaquine" title="Amodiaquine – 英语" lang="en" hreflang="en" data-title="Amodiaquine" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Amodiaquina" title="Amodiaquina – 西班牙语" lang="es" hreflang="es" data-title="Amodiaquina" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A2%D9%85%D9%88%D8%AF%DB%8C%D8%A7%DA%A9%DB%8C%D9%86" title="آمودیاکین – 波斯语" lang="fa" hreflang="fa" data-title="آمودیاکین" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Amodiakiini" title="Amodiakiini – 芬兰语" lang="fi" hreflang="fi" data-title="Amodiakiini" data-language-autonym="Suomi" data-language-local-name="芬兰语" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Amodiaquine" title="Amodiaquine – 法语" lang="fr" hreflang="fr" data-title="Amodiaquine" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B1%D5%B4%D5%B8%D5%A4%D5%AB%D5%A1%D6%84%D5%AB%D5%B6" title="Ամոդիաքին – 亚美尼亚语" lang="hy" hreflang="hy" data-title="Ամոդիաքին" data-language-autonym="Հայերեն" data-language-local-name="亚美尼亚语" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Amodiakuin" title="Amodiakuin – 印度尼西亚语" lang="id" hreflang="id" data-title="Amodiakuin" data-language-autonym="Bahasa Indonesia" data-language-local-name="印度尼西亚语" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Amodiachina" title="Amodiachina – 意大利语" lang="it" hreflang="it" data-title="Amodiachina" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A2%E3%83%A2%E3%82%B8%E3%82%A2%E3%82%AD%E3%83%B3" title="アモジアキン – 日语" lang="ja" hreflang="ja" data-title="アモジアキン" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%86%E0%AC%AE%E0%AD%8B%E0%AC%A1%E0%AC%BF%E0%AC%86%E0%AC%95%E0%AD%81%E0%AC%87%E0%AC%A8" title="ଆମୋଡିଆକୁଇନ – 奥里亚语" lang="or" hreflang="or" data-title="ଆମୋଡିଆକୁଇନ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="奥里亚语" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Amodiachina" title="Amodiachina – 波兰语" lang="pl" hreflang="pl" data-title="Amodiachina" data-language-autonym="Polski" data-language-local-name="波兰语" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Amodiachin%C4%83" title="Amodiachină – 罗马尼亚语" lang="ro" hreflang="ro" data-title="Amodiachină" data-language-autonym="Română" data-language-local-name="罗马尼亚语" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Amodiakvin" title="Amodiakvin – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Amodiakvin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Amodiakvin" title="Amodiakvin – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Amodiakvin" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Amodiakin" title="Amodiakin – 土耳其语" lang="tr" hreflang="tr" data-title="Amodiakin" data-language-autonym="Türkçe" data-language-local-name="土耳其语" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Amodiaquine" title="Amodiaquine – 越南语" lang="vi" hreflang="vi" data-title="Amodiaquine" data-language-autonym="Tiếng Việt" data-language-local-name="越南语" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q239569#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="命名空间"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E" title="浏览条目正文[c]" accesskey="c"><span>条目</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E" rel="discussion" title="关于此页面的讨论[t]" accesskey="t"><span>讨论</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="更改语言变体" > <label 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id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> <div id="mw-indicator-noteTA-8c2214c8" class="mw-indicator"><div class="mw-parser-output"><span class="skin-invert" typeof="mw:File"><span title="本页使用了标题或全文手工转换"><img alt="本页使用了标题或全文手工转换" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cd/Zh_conversion_icon_m.svg/35px-Zh_conversion_icon_m.svg.png" decoding="async" width="35" height="22" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cd/Zh_conversion_icon_m.svg/53px-Zh_conversion_icon_m.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/cd/Zh_conversion_icon_m.svg/70px-Zh_conversion_icon_m.svg.png 2x" data-file-width="32" data-file-height="20" /></span></span></div></div> </div> <div id="siteSub" class="noprint">维基百科，自由的百科全书</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="zh" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r83732082">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="國際非專利藥名（INN）：阿莫待奎">阿莫待奎</span></caption><tbody><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><a href="/wiki/File:Amodiaquine.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/Amodiaquine.svg/250px-Amodiaquine.svg.png" decoding="async" width="250" height="146" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/Amodiaquine.svg/375px-Amodiaquine.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/58/Amodiaquine.svg/500px-Amodiaquine.svg.png 2x" data-file-width="512" data-file-height="299" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">臨床資料</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><span class="ilh-all" data-orig-title="藥物命名法" data-lang-code="en" data-lang-name="英语" data-foreign-title="Drug nomenclature"><span class="ilh-page"><a href="/w/index.php?title=%E8%97%A5%E7%89%A9%E5%91%BD%E5%90%8D%E6%B3%95&action=edit&redlink=1" class="new" title="藥物命名法（页面不存在）">商品名</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Drug_nomenclature" class="extiw" title="en:Drug nomenclature"><span lang="en" dir="auto">Drug nomenclature</span></a></span>）</span></span></th><td class="infobox-data" style="">Amdaquine、Amobin、Camoquin及其他<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%BE%8E%E5%9C%8B%E8%A1%9B%E7%94%9F%E7%B3%BB%E7%B5%B1%E8%97%A5%E5%B8%AB%E5%8D%94%E6%9C%83" title="美國衛生系統藥師協會">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data" style=""><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/amodiaquine.html">国际药品名称</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%A7%A3%E5%89%96%E5%AD%A6%E6%B2%BB%E7%96%97%E5%AD%A6%E5%8F%8A%E5%8C%96%E5%AD%A6%E5%88%86%E7%B1%BB%E7%B3%BB%E7%BB%9F" title="解剖学治疗学及化学分类系统">ATC碼</a></th><td class="infobox-data" style=""><style data-mw-deduplicate="TemplateStyles:r82655520">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><a href="/w/index.php?title=ATC%E4%BB%A3%E7%A0%81_(P01)&action=edit&redlink=1" class="new" title="ATC代码 (P01)（页面不存在）">P01BA06</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=P01BA06">WHO</a></span>) </li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">识别信息</th></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC命名法</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol</div></li><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;"></div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/CAS%E5%8F%B7" title="CAS号">CAS号</a></th><td class="infobox-data" style=""><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=86-42-0">86-42-0</a></span> <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/2165">2165</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00613">DB00613</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.2080.html">2080</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%89%B9%E6%AE%8A%E6%88%90%E5%88%86%E6%A8%99%E8%AD%98" title="特殊成分標識">UNII</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/220236ED28">220236ED28</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D02922">D02922</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:2674">CHEBI:2674</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/ChEMBL682">ChEMBL682</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><span class="ilh-all" data-orig-title="CompTox化学品仪表板" data-lang-code="en" data-lang-name="英语" data-foreign-title="CompTox Chemicals Dashboard"><span class="ilh-page"><a href="/w/index.php?title=CompTox%E5%8C%96%E5%AD%A6%E5%93%81%E4%BB%AA%E8%A1%A8%E6%9D%BF&action=edit&redlink=1" class="new" title="CompTox化学品仪表板（页面不存在）">CompTox Dashboard</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/CompTox_Chemicals_Dashboard" class="extiw" title="en:CompTox Chemicals Dashboard"><span lang="en" dir="auto">CompTox Chemicals Dashboard</span></a></span>）</span></span> <span style="font-weight:normal">(<abbr title="美国国家环境保护局">EPA</abbr>)</span></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID2022597">DTXSID2022597</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q239569#P3117" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%AD%90%E6%B4%B2%E5%8C%96%E5%AD%B8%E5%93%81%E7%AE%A1%E7%90%86%E5%B1%80" title="歐洲化學品管理局"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.001.518">100.001.518</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q239569#P2566" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">化学信息</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a></th><td class="infobox-data" style=""><span title="Carbon">C</span><sub>20</sub><span title="Hydrogen">H</span><sub>22</sub><span title="Chlorine">Cl</span><span title="Nitrogen">N</span><sub>3</sub><span title="Oxygen">O</span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%91%A9%E5%B0%94%E8%B4%A8%E9%87%8F" title="摩尔质量">摩尔质量</a></th><td class="infobox-data" style="">355.87 g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;">3D模型（<span class="ilh-all" data-orig-title="JSmol" data-lang-code="en" data-lang-name="英语" data-foreign-title="JSmol"><span class="ilh-page"><a href="/w/index.php?title=JSmol&action=edit&redlink=1" class="new" title="JSmol（页面不存在）">JSmol</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/JSmol" class="extiw" title="en:JSmol"><span lang="en" dir="auto">JSmol</span></a></span>）</span></span>）</th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=Clc1cc2nccc%28c2cc1%29Nc3cc%28c%28O%29cc3%29CN%28CC%29CC">交互式图像</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E7%AE%80%E5%8C%96%E5%88%86%E5%AD%90%E7%BA%BF%E6%80%A7%E8%BE%93%E5%85%A5%E8%A7%84%E8%8C%83" title="简化分子线性输入规范">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Clc1cc2nccc(c2cc1)Nc3cc(c(O)cc3)CN(CC)CC</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:OVCDSSHSILBFBN-UHFFFAOYSA-N<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li></ul> </div></td></tr></tbody></table> <div id="noteTA-8c2214c8" class="noteTA"><div class="noteTA-title" data-noteta-code="zh-cn:阿莫地喹;zh-hk:阿莫地喹;zh-mo:阿莫地喹;zh-tw:阿莫待奎;"></div><div class="noteTA-local"><div data-noteta-code="zh-cn:阿莫地喹;zh-hk:阿莫地喹;zh-mo:阿莫地喹;zh-tw:阿莫待奎;"></div></div></div> <p><b>阿莫待奎</b>（英語：<span lang="en">Amodiaquine</span>，簡稱ADQ) ，别名<b>氨酚喹</b>，是一種用於治療<a href="/wiki/%E7%98%A7%E7%96%BE" class="mw-redirect" title="瘧疾">瘧疾</a>（包括尚未出現<a href="/wiki/%E4%BD%B5%E7%99%BC%E7%97%87" title="併發症">併發症</a>的<a href="/wiki/%E6%81%B6%E6%80%A7%E7%96%9F%E5%8E%9F%E8%99%AB" title="恶性疟原虫">惡性瘧原蟲</a>瘧疾）的藥物。<sup id="cite_ref-Na2012_2-0" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Co2003_3-0" class="reference"><a href="#cite_note-Co2003-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>建議此藥物與<a href="/wiki/%E9%9D%92%E8%92%BF%E7%90%A5%E9%85%AF" title="青蒿琥酯">青蒿琥酯</a>一起服用，以降低發生抗藥性風險。<sup id="cite_ref-Na2012_2-1" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>由於此藥物可能會產生罕見，但嚴重的副作用，通常不建議用於預防之用。<sup id="cite_ref-Na2012_2-2" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>但<a href="/wiki/%E4%B8%96%E7%95%8C%E8%A1%9B%E7%94%9F%E7%B5%84%E7%B9%94" class="mw-redirect" title="世界衛生組織">世界衛生組織</a> (WHO) 在2013年建議在兒童的高風險感染季節中將其與<span class="ilh-all" data-orig-title="磺胺多辛/乙胺嘧啶" data-lang-code="en" data-lang-name="英语" data-foreign-title="Sulfadoxine/pyrimethamine"><span class="ilh-page"><a href="/w/index.php?title=%E7%A3%BA%E8%83%BA%E5%A4%9A%E8%BE%9B/%E4%B9%99%E8%83%BA%E5%98%A7%E5%95%B6&action=edit&redlink=1" class="new" title="磺胺多辛/乙胺嘧啶（页面不存在）">磺胺多辛/乙胺嘧啶</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Sulfadoxine/pyrimethamine" class="extiw" title="en:Sulfadoxine/pyrimethamine"><span lang="en" dir="auto">Sulfadoxine/pyrimethamine</span></a></span>）</span></span>聯合，用於預防感染。<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>根據一份發表於2010年8月的研究報告，實驗者針對<a href="/wiki/%E8%BF%A6%E7%B4%8D" class="mw-redirect" title="迦納">迦納</a>的兒童採用阿莫待奎與青蒿琥酯組合，與採用阿莫待奎與磺胺多辛/乙胺嘧啶組合，進行季節性瘧疾預防性用藥，發現前者組合較後者更具有成本上的優勢。<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>此藥物經由<a href="/wiki/%E5%8F%A3%E6%9C%8D%E7%BB%99%E8%8D%AF" title="口服给药">口服</a>方式給藥。<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>阿莫待奎是一種與<a href="/wiki/%E6%B0%AF%E5%8C%96%E5%A5%8E%E5%AF%A7" class="mw-redirect" title="氯化奎寧">氯化奎寧</a>相關的<a href="/wiki/4-%E6%B0%A8%E5%9F%BA%E5%96%B9%E5%95%89" title="4-氨基喹啉">4-氨基喹啉</a>化合物。<sup id="cite_ref-Na2012_2-3" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>使用後的副作用與使用氯化奎寧相似，程度通常為輕微至中度。<sup id="cite_ref-Co2003_3-1" class="reference"><a href="#cite_note-Co2003-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>其中很少會出現<a href="/wiki/%E8%82%9D%E7%97%85" title="肝病">肝病</a>或<span class="ilh-all" data-orig-title="粒细胞减少症" data-lang-code="en" data-lang-name="英语" data-foreign-title="Agranulocytosis"><span class="ilh-page"><a href="/w/index.php?title=%E7%B2%92%E7%BB%86%E8%83%9E%E5%87%8F%E5%B0%91%E7%97%87&action=edit&redlink=1" class="new" title="粒细胞减少症（页面不存在）">粒细胞减少症</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Agranulocytosis" class="extiw" title="en:Agranulocytosis"><span lang="en" dir="auto">Agranulocytosis</span></a></span>）</span></span>（白細胞減少症）。<sup id="cite_ref-Na2012_2-4" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>過量服用後，可能會發生<a href="/wiki/%E9%A0%AD%E7%97%9B" title="頭痛">頭痛</a>、視力障礙、<a href="/wiki/%E7%99%B2%E7%99%87%E7%99%BC%E4%BD%9C" title="癲癇發作">癲癇發作</a>和<a href="/wiki/%E5%BF%83%E6%90%8F%E5%81%9C%E6%AD%A2" class="mw-redirect" title="心搏停止">心搏停止</a>。<sup id="cite_ref-Na2012_2-5" class="reference"><a href="#cite_note-Na2012-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>WHO建議孕婦可在懷孕中期和晚期，以及於哺乳期使用，但報告指出在懷孕早期使用，是否對於胎兒有害，證據仍然不足。<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>阿莫地奎於1948年開始生產。<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup>它已被列入<a href="/wiki/%E4%B8%96%E7%95%8C%E8%A1%9B%E7%94%9F%E7%B5%84%E7%B9%94%E5%9F%BA%E6%9C%AC%E8%97%A5%E7%89%A9%E6%A8%99%E6%BA%96%E6%B8%85%E5%96%AE" class="mw-redirect" title="世界衛生組織基本藥物標準清單">世界衛生組織基本藥物標準清單</a>之中。<sup id="cite_ref-WHO21st_9-0" class="reference"><a href="#cite_note-WHO21st-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-WHO22nd_10-0" class="reference"><a href="#cite_note-WHO22nd-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/%E6%AD%90%E7%9B%9F" class="mw-redirect" title="歐盟">歐盟</a>或美國等國家因為阿莫待奎的副作用而不再使用，WHO於1990年將其由其瘧疾控制計畫中剔除。<sup id="cite_ref-Elsevier_Science_11-0" class="reference"><a href="#cite_note-Elsevier_Science-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup>但此藥物仍在其他地區（包括<a href="/wiki/%E9%9D%9E%E6%B4%B2" title="非洲">非洲</a><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> 和<a href="/wiki/%E5%A4%A7%E6%B4%8B%E6%B4%B2" title="大洋洲">大洋洲</a>）使用。<sup id="cite_ref-Elsevier_Science_11-1" class="reference"><a href="#cite_note-Elsevier_Science-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="醫療用途"><span id=".E9.86.AB.E7.99.82.E7.94.A8.E9.80.94"></span>醫療用途</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=1" title="编辑章节：醫療用途"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>阿莫待奎是非洲於瘧疾<a href="/wiki/%E8%81%94%E5%90%88%E7%96%97%E6%B3%95" title="联合疗法">聯合療法</a>中的重要藥物。<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup>它通常與青蒿琥酯聯合使用，稱為<a href="/wiki/%E9%9D%92%E8%92%BF%E7%B4%A0" title="青蒿素">青蒿素</a>聯合療法（ACT），以治療尚未出現併發症的惡性瘧原蟲瘧疾。<sup id="cite_ref-:02_14-0" class="reference"><a href="#cite_note-:02-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p>此藥物也可與磺胺多辛/乙胺嘧啶（複方劑）聯合使用。<sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p><p>非洲迄2006年已有39個國家更新其國家藥物政策，將青蒿素聯合療法 (ACT) 納入瘧疾病例管理指南。口服青蒿素不僅可單獨使用 (對於非抗藥性瘧疾)，也可與其他長效抗瘧疾藥物，例如阿莫待奎、<a href="/wiki/%E7%BE%8E%E7%88%BE%E5%A5%8E%E5%AF%A7" title="美爾奎寧">美爾奎寧</a>、磺胺多辛/乙胺嘧啶或是<a href="/wiki/%E8%8B%AF%E8%8A%B4%E9%86%87" title="苯芴醇">苯芴醇</a>組合使用，達到ACT療法的目的。<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p><p>阿莫待奎也可對抗具氯化奎寧抗藥性的惡性瘧原蟲菌株，但其對抗氯化奎寧抗藥性菌株的活性存有地域上的差異。<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="與其他藥物交互作用"><span id=".E8.88.87.E5.85.B6.E4.BB.96.E8.97.A5.E7.89.A9.E4.BA.A4.E4.BA.92.E4.BD.9C.E7.94.A8"></span>與其他藥物交互作用</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=2" title="编辑章节：與其他藥物交互作用"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>有報導稱接受<a href="/wiki/%E9%BD%90%E5%A4%9A%E5%A4%AB%E5%AE%9A" title="齐多夫定">齊多夫定</a>或<a href="/wiki/%E4%BE%9D%E6%B3%95%E9%9F%A6%E4%BB%91" title="依法韦仑">依法韋倫</a>以治療<a href="/wiki/%E6%84%9B%E6%BB%8B%E7%97%85" class="mw-redirect" title="愛滋病">愛滋病</a>的患者，當同時採含阿莫待奎的ACT方案時，其肝臟毒性會增加，因此建議此類人避免使用阿莫待奎。<sup id="cite_ref-:02_14-1" class="reference"><a href="#cite_note-:02-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="藥物動力學和藥物遺傳學"><span id=".E8.97.A5.E7.89.A9.E5.8B.95.E5.8A.9B.E5.AD.B8.E5.92.8C.E8.97.A5.E7.89.A9.E9.81.BA.E5.82.B3.E5.AD.B8"></span>藥物動力學和藥物遺傳學</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=3" title="编辑章节：藥物動力學和藥物遺傳學"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>阿莫待奎因為會經過肝臟廣泛的<a href="/wiki/%E9%A6%96%E8%BF%87%E6%95%88%E5%BA%94" title="首过效应">首過效應</a>，在人體中的<a href="/wiki/%E7%94%9F%E7%89%A9%E5%8D%8A%E8%A1%B0%E6%9C%9F" title="生物半衰期">生物半衰期</a>為5.3–7.7小時。<sup id="cite_ref-Mechanism_20-0" class="reference"><a href="#cite_note-Mechanism-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup>阿莫待奎主要以去乙基阿莫待奎（N-desethylamodiaquine）的形式由<a href="/wiki/%E8%83%86%E6%B1%81" title="胆汁">胆汁</a>排出。<sup id="cite_ref-Mechanism_20-1" class="reference"><a href="#cite_note-Mechanism-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p><p>此藥物經由<a href="/wiki/%E7%BB%86%E8%83%9E%E8%89%B2%E7%B4%A0P450" title="细胞色素P450">細胞色素P450</a>中的<span class="ilh-all" data-orig-title="CYP2C8" data-lang-code="en" data-lang-name="英语" data-foreign-title="CYP2C8"><span class="ilh-page"><a href="/w/index.php?title=CYP2C8&action=edit&redlink=1" class="new" title="CYP2C8（页面不存在）">CYP2C8</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/CYP2C8" class="extiw" title="en:CYP2C8"><span lang="en" dir="auto">CYP2C8</span></a></span>）</span></span>酵素在肝臟被生物轉化為主要代謝物 - 去乙基阿莫待奎。在阿莫待奎使用者中，已有幾種罕見但嚴重的副作用發生，這些副作用與CYP2C8<a href="/wiki/%E7%AD%89%E4%BD%8D%E5%9F%BA%E5%9B%A0" title="等位基因">等位基因</a>的變異有關。阿莫待奎代謝不良的人在瘧疾的治療效果會較低，且毒性會增加。<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup>目前已進行幾項研究來確定於<a href="/wiki/%E6%9D%B1%E9%9D%9E" class="mw-redirect" title="東非">東非</a>的瘧疾患者中，其CYP2C8等位基因的盛行率，初步顯示變異等位基因在此地有顯著的盛行率。<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup>有約3.6%的受研究族群在接受阿莫待奎治療時表現出不良反應升高或治療結果降低的風險。這些資訊對於在東非制定<span class="ilh-all" data-orig-title="藥物安全計劃" data-lang-code="en" data-lang-name="英语" data-foreign-title="pharmacovigilance"><span class="ilh-page"><a href="/w/index.php?title=%E8%97%A5%E7%89%A9%E5%AE%89%E5%85%A8%E8%A8%88%E5%8A%83&action=edit&redlink=1" class="new" title="藥物安全計劃（页面不存在）">藥物安全計劃</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/pharmacovigilance" class="extiw" title="en:pharmacovigilance"><span lang="en" dir="auto">pharmacovigilance</span></a></span>）</span></span>時有其用處，且對於在CYP2C8同位基因變異頻率高的地區開立抗瘧藥物處方時會將其作為重要的臨床考慮。 </p> <div class="mw-heading mw-heading2"><h2 id="參見"><span id=".E5.8F.83.E8.A6.8B"></span>參見</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=4" title="编辑章节：參見"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><span class="ilh-all" data-orig-title="FGI-104" data-lang-code="en" data-lang-name="英语" data-foreign-title="FGI-104"><span class="ilh-page"><a href="/w/index.php?title=FGI-104&action=edit&redlink=1" class="new" title="FGI-104（页面不存在）">FGI-104</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/FGI-104" class="extiw" title="en:FGI-104"><span lang="en" dir="auto">FGI-104</span></a></span>）</span></span>，此實驗性藥物的結構與阿莫待奎相似</li></ul> <div class="mw-heading mw-heading2"><h2 id="參考文獻"><span id=".E5.8F.83.E8.80.83.E6.96.87.E7.8D.BB"></span>參考文獻</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=5" title="编辑章节：參考文獻"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/amodiaquine.html">Amodiaquine</a>. drugs.com. <span class="reference-accessdate"> [<span 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The Cochrane Database of Systematic Reviews. 2003, (2): CD000016. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6532704"><span title="公共医学中心">PMC 6532704</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12804382"><span title="公共医学识别码">PMID 12804382</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1002%2F14651858.CD000016"><span title="數位物件識別號">doi:10.1002/14651858.CD000016</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Amodiaquine+for+treating+malaria&rft.au=Mussano%2C+P&rft.aufirst=P&rft.aulast=Olliaro&rft.date=2003&rft.genre=article&rft.issue=2&rft.jtitle=The+Cochrane+Database+of+Systematic+Reviews&rft.pages=CD000016&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6532704&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6532704&rft_id=info%3Adoi%2F10.1002%2F14651858.CD000016&rft_id=info%3Apmid%2F12804382&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><cite class="citation book"><a rel="nofollow" class="external text" href="https://apps.who.int/iris/bitstream/handle/10665/85726/9789241504737_eng.pdf">Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children: a field guide.</a> <span style="font-size:85%;">(PDF)</span>. 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August 2013. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-92-4-150473-7" title="Special:网络书源/978-92-4-150473-7"><span title="国际标准书号">ISBN</span> 978-92-4-150473-7</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.btitle=Seasonal+malaria+chemoprevention+with+sulfadoxine%E2%80%93pyrimethamine+plus+amodiaquine+in+children%3A+a+field+guide.&rft.date=2013-08&rft.genre=book&rft.isbn=978-92-4-150473-7&rft.place=Geneva&rft.pub=The+World+Health+Organization&rft_id=https%3A%2F%2Fapps.who.int%2Firis%2Fbitstream%2Fhandle%2F10665%2F85726%2F9789241504737_eng.pdf&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><cite class="citation journal">Conteh, Lesong; Patouillard, Edith. <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20808923/">Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children</a>. PLoS. 2010-08-17, <b>5</b> (8) <span class="reference-accessdate"> [<span class="nowrap">2024-05-16</span>]</span>. <a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0012223"><span title="數位物件識別號">doi:10.1371/journal.pone.0012223</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Cost+effectiveness+of+seasonal+intermittent+preventive+treatment+using+amodiaquine+%26+artesunate+or+sulphadoxine-pyrimethamine+in+Ghanaian+children&rft.au=Patouillard%2C+Edith&rft.aufirst=Lesong&rft.aulast=Conteh&rft.date=2010-08-17&rft.genre=article&rft.issue=8&rft.jtitle=PLoS&rft.volume=5&rft_id=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F20808923%2F&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0012223&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><cite class="citation book"><a rel="nofollow" class="external text" href="https://www.sciencedirect.com/book/9781416032915/pharmacology-and-therapeutics">Pharmacology and Therapeutics Principles to Practice（2008）</a>. Elsevier Inc. <span class="reference-accessdate"> [<span class="nowrap">2024-05-16</span>]</span>. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-1-4160-3291-5" title="Special:网络书源/978-1-4160-3291-5"><span title="国际标准书号">ISBN</span> 978-1-4160-3291-5</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.btitle=Pharmacology+and+Therapeutics+Principles+to+Practice%EF%BC%882008%EF%BC%89&rft.genre=book&rft.isbn=978-1-4160-3291-5&rft.pub=Elsevier+Inc.&rft_id=https%3A%2F%2Fwww.sciencedirect.com%2Fbook%2F9781416032915%2Fpharmacology-and-therapeutics&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="https://www.who.int/publications-detail-redirect/guidelines-for-malaria">WHO Guidelines for malaria</a>. www.who.int. <span class="reference-accessdate"> [<span class="nowrap">2024-01-22</span>]</span> <span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="连接到英语网页">（英语）</span>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=WHO+Guidelines+for+malaria&rft.genre=unknown&rft.jtitle=www.who.int&rft_id=https%3A%2F%2Fwww.who.int%2Fpublications-detail-redirect%2Fguidelines-for-malaria&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><cite class="citation book">Ahmad I, Ahmad T, Usmanghani K. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=3mP9TYffnewC&pg=PA44">Amodiaquine hydrochloride</a>. Profiles of Drug Substances, Excipients and Related Methodology. Analytical Profiles of Drug Substances and Excipients <b>21</b>. 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License: CC BY-NC-SA 3.0 IGO.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.au=World+Health+Organization&rft.btitle=World+Health+Organization+model+list+of+essential+medicines%3A+21st+list+2019&rft.date=2019&rft.genre=book&rft.place=Geneva&rft.pub=World+Health+Organization&rft_id=info%3Ahdl%2F10665%2F325771&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-WHO22nd-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-WHO22nd_10-0">^</a></b></span> <span class="reference-text"><cite class="citation book"><a href="/wiki/World_Health_Organization" class="mw-redirect" title="World Health Organization">World Health Organization</a>. World Health Organization model list of essential medicines: 22nd list (2021). 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August 2001, <b>358</b> (9279): 368–374. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/11502317"><span title="公共医学识别码">PMID 11502317</span></a>. <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:42745422"><span title="Semantic Scholar">S2CID 42745422</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0140-6736%2801%2905557-X"><span title="數位物件識別號">doi:10.1016/S0140-6736(01)05557-X</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Amodiaquine%2C+sulfadoxine%2Fpyrimethamine%2C+and+combination+therapy+for+treatment+of+uncomplicated+falciparum+malaria+in+Kampala%2C+Uganda%3A+a+randomised+trial&rft.au=Charlebois%2C+ED&rft.au=Dorsey%2C+G&rft.au=Gasasira%2C+A&rft.au=Kamya%2C+MR&rft.au=Ndeezi%2C+G&rft.au=Rosenthal%2C+PJ&rft.aufirst=SG&rft.aulast=Staedke&rft.date=2001-08&rft.genre=article&rft.issue=9279&rft.jtitle=Lancet&rft.pages=368-374&rft.volume=358&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A42745422&rft_id=info%3Adoi%2F10.1016%2FS0140-6736%2801%2905557-X&rft_id=info%3Apmid%2F11502317&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text"><cite class="citation book">World Health Organization. Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children: a field guide. World Health Organization. 2013. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-92-4-150473-7" title="Special:网络书源/978-92-4-150473-7"><span title="国际标准书号">ISBN</span> 978-92-4-150473-7</a>. <span class="plainlinks"><a rel="nofollow" class="external text" href="//hdl.handle.net/10665%2F85726"><span title="Handle System">hdl:10665/85726</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.au=World+Health+Organization&rft.btitle=Seasonal+malaria+chemoprevention+with+sulfadoxine%E2%80%93pyrimethamine+plus+amodiaquine+in+children%3A+a+field+guide&rft.date=2013&rft.genre=book&rft.isbn=978-92-4-150473-7&rft.pub=World+Health+Organization&rft_id=info%3Ahdl%2F10665%2F85726&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-17">^</a></b></span> <span class="reference-text"><cite class="citation journal">Odunfa, OO; Adegoke, OA. <a rel="nofollow" class="external text" href="https://www.researchgate.net/publication/43561149_Pharmaceutical_Equivalence_of_Some_Commercial_Samples_of_Artesunate_and_Amodiaquine_Tablets_Sold_in_Southwestern_Nigeria">Pharmaceutical Equivalence of Some Commercial Samples of Artesunate and Amodiaquine Tablets Sold in Southwestern Nigeria</a>. Tropical Journal of Pharmaceutical Research. December 2009, <b>8</b> (6): 491–499 <span class="reference-accessdate"> [<span class="nowrap">2024-05-16</span>]</span>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Pharmaceutical+Equivalence+of+Some+Commercial+Samples+of+Artesunate+and+Amodiaquine+Tablets+Sold+in+Southwestern+Nigeria&rft.au=Adegoke%2C+OA&rft.aufirst=OO&rft.aulast=Odunfa&rft.date=2009-12&rft.genre=article&rft.issue=6&rft.jtitle=Tropical+Journal+of+Pharmaceutical+Research&rft.pages=491-499&rft.volume=8&rft_id=https%3A%2F%2Fwww.researchgate.net%2Fpublication%2F43561149_Pharmaceutical_Equivalence_of_Some_Commercial_Samples_of_Artesunate_and_Amodiaquine_Tablets_Sold_in_Southwestern_Nigeria&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-18">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/amodiaquine#section=Top">Amodiaquine</a>. PubChem. U.S. National Library of Medicine. <span class="reference-accessdate"> [<span class="nowrap">2016-10-28</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20161029043608/https://pubchem.ncbi.nlm.nih.gov/compound/amodiaquine#section=Top">存档</a>于2016-10-29）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Amodiaquine&rft.genre=unknown&rft.jtitle=PubChem&rft_id=https%3A%2F%2Fpubchem.ncbi.nlm.nih.gov%2Fcompound%2Famodiaquine%23section%3DTop&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-19">^</a></b></span> <span class="reference-text"><cite class="citation book">Bennett, John Eugene; Dolin, Raphael; Blaser, Martin J. (编). 41 - Antimalarial Drugs. Mandell, Douglas, and Bennett's principles and practice of infectious diseases Ninth. Philadelphia, PA: Elsevier. 2020: 519–534. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-0-323-48255-4" title="Special:网络书源/978-0-323-48255-4"><span title="国际标准书号">ISBN</span> 978-0-323-48255-4</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=41+-+Antimalarial+Drugs&rft.au=Blaser%2C+Martin+J.&rft.au=Dolin%2C+Raphael&rft.aufirst=John+Eugene&rft.aulast=Bennett&rft.btitle=Mandell%2C+Douglas%2C+and+Bennett%27s+principles+and+practice+of+infectious+diseases&rft.date=2020&rft.edition=Ninth&rft.genre=bookitem&rft.isbn=978-0-323-48255-4&rft.pages=519-534&rft.place=Philadelphia%2C+PA&rft.pub=Elsevier&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Mechanism-20"><span class="mw-cite-backlink">^ <a href="#cite_ref-Mechanism_20-0"><sup><b>20.0</b></sup></a> <a href="#cite_ref-Mechanism_20-1"><sup><b>20.1</b></sup></a></span> <span class="reference-text"><cite class="citation book"><a rel="nofollow" class="external text" href="https://www.sciencedirect.com/book/9780081012109/antimalarial-agents">Antimalarial Agents Design and Mechanism of Action （2020）</a>. Elsevier Ltd. <span class="reference-accessdate"> [<span class="nowrap">2024-05-16</span>]</span>. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-0-08-101210-9" title="Special:网络书源/978-0-08-101210-9"><span title="国际标准书号">ISBN</span> 978-0-08-101210-9</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.btitle=Antimalarial+Agents+Design+and+Mechanism+of+Action+%EF%BC%882020%EF%BC%89&rft.genre=book&rft.isbn=978-0-08-101210-9&rft.pub=Elsevier+Ltd&rft_id=https%3A%2F%2Fwww.sciencedirect.com%2Fbook%2F9780081012109%2Fantimalarial-agents&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-21">^</a></b></span> <span class="reference-text"><cite class="citation journal">Elyazar IR, Hay SI, Baird JK. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3075886">Malaria distribution, prevalence, drug resistance and control in Indonesia</a>. Advances in Parasitology. April 2011, <b>74</b> (74): 41–175. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-0-12-385897-9" title="Special:网络书源/978-0-12-385897-9"><span title="国际标准书号">ISBN</span> 978-0-12-385897-9</a>. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3075886"><span title="公共医学中心">PMC 3075886</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/21295677"><span title="公共医学识别码">PMID 21295677</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FB978-0-12-385897-9.00002-1"><span title="數位物件識別號">doi:10.1016/B978-0-12-385897-9.00002-1</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Malaria+distribution%2C+prevalence%2C+drug+resistance+and+control+in+Indonesia&rft.au=Baird%2C+JK&rft.au=Hay%2C+SI&rft.aufirst=IR&rft.aulast=Elyazar&rft.date=2011-04&rft.genre=article&rft.isbn=978-0-12-385897-9&rft.issue=74&rft.jtitle=Advances+in+Parasitology&rft.pages=41-175&rft.volume=74&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3075886&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3075886&rft_id=info%3Adoi%2F10.1016%2FB978-0-12-385897-9.00002-1&rft_id=info%3Apmid%2F21295677&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-22">^</a></b></span> <span class="reference-text"><cite class="citation journal">Roederer MW, McLeod H, Juliano JJ. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3209725">Can pharmacogenomics improve malaria drug policy?</a>. Bulletin of the World Health Organization. November 2011, <b>89</b> (11): 838–845. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3209725"><span title="公共医学中心">PMC 3209725</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/22084530"><span title="公共医学识别码">PMID 22084530</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.2471%2FBLT.11.087320"><span title="數位物件識別號">doi:10.2471/BLT.11.087320</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Can+pharmacogenomics+improve+malaria+drug+policy%3F&rft.au=Juliano%2C+JJ&rft.au=McLeod%2C+H&rft.aufirst=MW&rft.aulast=Roederer&rft.date=2011-11&rft.genre=article&rft.issue=11&rft.jtitle=Bulletin+of+the+World+Health+Organization&rft.pages=838-845&rft.volume=89&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3209725&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3209725&rft_id=info%3Adoi%2F10.2471%2FBLT.11.087320&rft_id=info%3Apmid%2F22084530&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="外部連結"><span id=".E5.A4.96.E9.83.A8.E9.80.A3.E7.B5.90"></span>外部連結</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&action=edit&section=6" title="编辑章节：外部連結"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><cite class="citation web"><a rel="nofollow" class="external text" href="https://druginfo.nlm.nih.gov/drugportal/name/amodiaquine">Amodiaquine</a>. Drug Information Portal. U.S. National Library of Medicine.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E8%8E%AB%E5%BE%85%E5%A5%8E&rft.atitle=Amodiaquine&rft.genre=unknown&rft.jtitle=Drug+Information+Portal&rft_id=https%3A%2F%2Fdruginfo.nlm.nih.gov%2Fdrugportal%2Fname%2Famodiaquine&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li></ul> <style data-mw-deduplicate="TemplateStyles:r82655521">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:#f9f9f9;display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output 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class="extiw" title="d:Wikidata:Scholia/zh">Scholia</a>上有關<a href="https://iw.toolforge.org/scholia/Q239569" class="extiw" title="toolforge:scholia/Q239569"><b>阿莫地喹<small>（Q239569）</small></b></a>的信息</div></div> </div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist 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dir="auto">antiprotozoal agent</span></a></span>）</span></span>– 抗<a href="/wiki/%E5%9B%8A%E6%B3%A1%E8%97%BB%E7%B1%BB" title="囊泡藻类">囊泡藻界</a>寄生蟲藥（<span class="ilh-all" data-orig-title="ATC code P01" data-lang-code="en" data-lang-name="英语" data-foreign-title="ATC code P01"><span class="ilh-page"><a href="/w/index.php?title=ATC_code_P01&action=edit&redlink=1" class="new" title="ATC code P01（页面不存在）">P01</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/ATC_code_P01" class="extiw" title="en:ATC code P01"><span lang="en" dir="auto">ATC code P01</span></a></span>）</span></span>）</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E5%9B%8A%E6%B3%A1%E8%99%AB%E7%B1%BB" class="mw-redirect" title="囊泡虫类">囊泡虫类</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E9%A0%82%E8%A4%87%E9%96%80" title="頂複門">頂複門</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E9%A1%9E%E9%8C%90%E9%AB%94%E7%B6%B1" title="類錐體綱">類錐體綱</a><br /><span class="ilh-all" data-orig-title="抗球蟲藥" data-lang-code="en" data-lang-name="英语" data-foreign-title="Coccidiostat"><span class="ilh-page"><a href="/w/index.php?title=%E6%8A%97%E7%90%83%E8%9F%B2%E8%97%A5&action=edit&redlink=1" class="new" title="抗球蟲藥（页面不存在）">抗球蟲藥</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Coccidiostat" class="extiw" title="en:Coccidiostat"><span lang="en" dir="auto">Coccidiostat</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E9%9A%90%E5%AD%A2%E5%AD%90%E8%99%AB%E7%97%85" title="隐孢子虫病">隐孢子虫病</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=%E5%99%BB%E5%94%91%E7%AB%8B%E5%BE%B7&action=edit&redlink=1" class="new" title="噻唑立德（页面不存在）">噻唑立德</a>（<a href="/wiki/%E7%A1%9D%E5%94%91%E5%B0%BC%E7%89%B9" title="硝唑尼特">硝唑尼特</a>）</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="等孢球蟲病" data-lang-code="en" data-lang-name="英语" data-foreign-title="Isosporiasis"><span class="ilh-page"><a href="/w/index.php?title=%E7%AD%89%E5%AD%A2%E7%90%83%E8%9F%B2%E7%97%85&action=edit&redlink=1" class="new" title="等孢球蟲病（页面不存在）">等孢球蟲病</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Isosporiasis" class="extiw" title="en:Isosporiasis"><span lang="en" dir="auto">Isosporiasis</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%A4%87%E6%96%B9%E6%96%B0%E8%AB%BE%E6%98%8E" title="複方新諾明">複方新諾明</a><sup>#</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E5%BC%93%E8%9F%B2%E7%97%87" title="弓蟲症">弓蟲症</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E4%B9%99%E8%83%BA%E5%98%A7%E5%95%B6" title="乙胺嘧啶">乙胺嘧啶</a></li> <li><a href="/wiki/%E7%A3%BA%E8%83%BA%E5%98%A7%E5%95%B6" title="磺胺嘧啶">磺胺嘧啶</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%84%A1%E9%A1%9E%E9%8C%90%E9%AB%94%E7%B6%B1" title="無類錐體綱">無類錐體綱</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E6%8A%97%E7%96%9F%E8%8D%AF" title="抗疟药">抗疟药</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">單獨劑</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="瘧原蟲色素" data-lang-code="en" data-lang-name="英语" data-foreign-title="Hemozoin"><span class="ilh-page"><a href="/w/index.php?title=%E7%98%A7%E5%8E%9F%E8%9F%B2%E8%89%B2%E7%B4%A0&action=edit&redlink=1" class="new" title="瘧原蟲色素（页面不存在）">瘧原蟲色素<br />抑制劑</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Hemozoin" class="extiw" title="en:Hemozoin"><span lang="en" dir="auto">Hemozoin</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E6%B0%A8%E5%9F%BA%E5%96%B9%E5%95%89" title="氨基喹啉">氨基喹啉</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/4-%E6%B0%A8%E5%9F%BA%E5%96%B9%E5%95%89" title="4-氨基喹啉">(4-)</a>：<a class="mw-selflink selflink">阿莫待奎</a><sup>#</sup></li> <li><a href="/wiki/%E6%B0%AF%E5%96%B9" title="氯喹">氯喹</a><sup>#</sup></li> <li><a href="/wiki/%E7%BE%9F%E6%B0%AF%E5%96%B9" title="羟氯喹">羟氯喹</a><sup>#</sup></li></ul> <ul><li><a href="/wiki/8-%E6%B0%A8%E5%9F%BA%E5%96%B9%E5%95%89" title="8-氨基喹啉">(8-)</a>：<a href="/wiki/%E6%99%AE%E4%BE%86%E9%A6%AC%E5%A5%8E%E5%AF%A7" title="普來馬奎寧">伯氨喹</a><sup>#</sup></li> <li><span class="ilh-all" data-orig-title="巴馬喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="pamaquine"><span class="ilh-page"><a href="/w/index.php?title=%E5%B7%B4%E9%A6%AC%E5%96%B9&action=edit&redlink=1" class="new" title="巴馬喹（页面不存在）">巴馬喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/pamaquine" class="extiw" title="en:pamaquine"><span lang="en" dir="auto">pamaquine</span></a></span>）</span></span><sup>‡</sup>（撲瘧喹啉）</li> <li><span class="ilh-all" data-orig-title="他非諾喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="tafenoquine"><span class="ilh-page"><a href="/w/index.php?title=%E4%BB%96%E9%9D%9E%E8%AB%BE%E5%96%B9&action=edit&redlink=1" class="new" title="他非諾喹（页面不存在）">他非諾喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/tafenoquine" class="extiw" title="en:tafenoquine"><span lang="en" dir="auto">tafenoquine</span></a></span>）</span></span><sup>†</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">4-甲醇喹啉</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E7%BE%8E%E7%88%BE%E5%A5%8E%E5%AF%A7" title="美爾奎寧">美爾奎寧</a><sup>#</sup></li> <li><a href="/wiki/%E5%A5%8E%E5%AF%A7" title="奎寧">奎寧</a><sup>#</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其它製劑</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%8B%AF%E8%8A%B4%E9%86%87" title="苯芴醇">苯芴醇</a> <ul><li><a href="/wiki/%E8%A4%87%E6%96%B9%E8%92%BF%E7%94%B2%E9%86%9A" title="複方蒿甲醚">+蒿甲醚</a><sup>#</sup></li></ul></li></ul> <ul><li><a href="/wiki/%E9%B9%B5%E6%B3%9B%E7%BE%A4" title="鹵泛群">鹵泛群</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="抗葉酸製劑" data-lang-code="en" data-lang-name="英语" data-foreign-title="Antifolate"><span class="ilh-page"><a href="/w/index.php?title=%E6%8A%97%E8%91%89%E9%85%B8%E8%A3%BD%E5%8A%91&action=edit&redlink=1" class="new" title="抗葉酸製劑（页面不存在）">抗葉酸製劑</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Antifolate" class="extiw" title="en:Antifolate"><span lang="en" dir="auto">Antifolate</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="二氫葉酸還原酶抑製劑" data-lang-code="en" data-lang-name="英语" data-foreign-title="Dihydrofolate reductase inhibitor"><span class="ilh-page"><a href="/w/index.php?title=%E4%BA%8C%E6%B0%AB%E8%91%89%E9%85%B8%E9%82%84%E5%8E%9F%E9%85%B6%E6%8A%91%E8%A3%BD%E5%8A%91&action=edit&redlink=1" class="new" title="二氫葉酸還原酶抑製劑（页面不存在）">DHFR抑制劑</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Dihydrofolate_reductase_inhibitor" class="extiw" title="en:Dihydrofolate reductase inhibitor"><span lang="en" dir="auto">Dihydrofolate reductase inhibitor</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E4%B9%99%E8%83%BA%E5%98%A7%E5%95%B6" title="乙胺嘧啶">乙胺嘧啶</a></li> <li><a href="/wiki/%E7%8E%AF%E6%B0%AF%E8%83%8D" title="环氯胍">环氯胍</a></li> <li><a href="/wiki/%E9%9B%99%E8%83%8D%E9%A1%9E" title="雙胍類">雙胍類</a> <ul><li><a href="/wiki/%E6%B0%AF%E4%B8%99%E8%83%8D" title="氯丙胍">氯丙胍</a></li> <li><span class="ilh-all" data-orig-title="氯胍" data-lang-code="en" data-lang-name="英语" data-foreign-title="proguanil"><span class="ilh-page"><a href="/w/index.php?title=%E6%B0%AF%E8%83%8D&action=edit&redlink=1" class="new" title="氯胍（页面不存在）">氯胍</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/proguanil" class="extiw" title="en:proguanil"><span lang="en" dir="auto">proguanil</span></a></span>）</span></span><sup>#</sup></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%A3%BA%E8%83%BA%E7%B1%BB%E8%8D%AF%E7%89%A9" title="磺胺类药物">磺胺类药物</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E7%A3%BA%E8%83%BA%E5%A4%9A%E8%BE%9B" title="磺胺多辛">磺胺多辛</a></li> <li><a href="/wiki/%E7%A3%BA%E8%83%BA%E6%9E%97" title="磺胺林">磺胺林</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">共製劑</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><span class="ilh-all" data-orig-title="磺胺多辛/乙胺嘧啶" data-lang-code="en" data-lang-name="英语" data-foreign-title="sulfadoxine/pyrimethamine"><span class="ilh-page"><a href="/w/index.php?title=%E7%A3%BA%E8%83%BA%E5%A4%9A%E8%BE%9B/%E4%B9%99%E8%83%BA%E5%98%A7%E5%95%B6&action=edit&redlink=1" class="new" title="磺胺多辛/乙胺嘧啶（页面不存在）">磺胺多辛/乙胺嘧啶</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/sulfadoxine/pyrimethamine" class="extiw" title="en:sulfadoxine/pyrimethamine"><span lang="en" dir="auto">sulfadoxine/pyrimethamine</span></a></span>）</span></span>（SP/周效磺胺）<sup>#</sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="倍半萜內酯" data-lang-code="en" data-lang-name="英语" data-foreign-title="Sesquiterpene lactones"><span class="ilh-page"><a href="/w/index.php?title=%E5%80%8D%E5%8D%8A%E8%90%9C%E5%85%A7%E9%85%AF&action=edit&redlink=1" class="new" title="倍半萜內酯（页面不存在）">倍半萜內酯</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Sesquiterpene_lactones" class="extiw" title="en:Sesquiterpene lactones"><span lang="en" dir="auto">Sesquiterpene lactones</span></a></span>）</span></span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%92%BF%E7%94%B2%E9%86%9A" title="蒿甲醚">蒿甲醚</a><sup>#</sup></li> <li><a href="/wiki/%E9%9D%92%E8%92%BF%E7%B4%A0" title="青蒿素">青蒿素</a></li> <li><a href="/wiki/%E8%92%BF%E4%B9%99%E9%86%9A" title="蒿乙醚">蒿乙醚</a></li> <li><a href="/wiki/%E9%9D%92%E8%92%BF%E7%90%A5%E9%85%AF" title="青蒿琥酯">青蒿琥酯</a><sup>#</sup></li> <li><a href="/wiki/%E5%8F%8C%E6%B0%A2%E9%9D%92%E8%92%BF%E7%B4%A0" title="双氢青蒿素">双氢青蒿素</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他製劑</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><span class="ilh-all" data-orig-title="阿托伐醌" data-lang-code="en" data-lang-name="英语" data-foreign-title="atovaquone"><span class="ilh-page"><a href="/w/index.php?title=%E9%98%BF%E6%89%98%E4%BC%90%E9%86%8C&action=edit&redlink=1" class="new" title="阿托伐醌（页面不存在）">阿托伐醌</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/atovaquone" class="extiw" title="en:atovaquone"><span lang="en" dir="auto">atovaquone</span></a></span>）</span></span>（<span class="ilh-all" data-orig-title="阿托伐醌/氯胍" data-lang-code="en" data-lang-name="英语" data-foreign-title="Atovaquone/proguanil"><span class="ilh-page"><a href="/w/index.php?title=%E9%98%BF%E6%89%98%E4%BC%90%E9%86%8C/%E6%B0%AF%E8%83%8D&action=edit&redlink=1" class="new" title="阿托伐醌/氯胍（页面不存在）">+氯胍</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Atovaquone/proguanil" class="extiw" title="en:Atovaquone/proguanil"><span lang="en" dir="auto">Atovaquone/proguanil</span></a></span>）</span></span>）</li> <li><a href="/wiki/%E5%9B%9B%E7%92%B0%E9%BB%B4%E7%B4%A0" title="四環黴素">四環黴素</a></li> <li><a href="/wiki/%E5%A4%9A%E8%A5%BF%E7%8E%AF%E7%B4%A0" title="多西环素">多西环素</a><sup>#</sup></li> <li><a href="/wiki/%E5%85%8B%E6%9E%97%E9%BB%B4%E7%B4%A0" title="克林黴素">克林黴素</a></li> <li><span class="ilh-all" data-orig-title="米帕林" data-lang-code="en" data-lang-name="英语" data-foreign-title="mepacrine"><span class="ilh-page"><a href="/w/index.php?title=%E7%B1%B3%E5%B8%95%E6%9E%97&action=edit&redlink=1" class="new" title="米帕林（页面不存在）">米帕林</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/mepacrine" class="extiw" title="en:mepacrine"><span lang="en" dir="auto">mepacrine</span></a></span>）</span></span></li> <li><a href="/wiki/%E5%92%AF%E8%90%98%E5%95%B6" title="咯萘啶">咯萘啶</a></li> <li><span class="ilh-all" data-orig-title="哌喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="piperaquine"><span class="ilh-page"><a href="/w/index.php?title=%E5%93%8C%E5%96%B9&action=edit&redlink=1" class="new" title="哌喹（页面不存在）">哌喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/piperaquine" class="extiw" title="en:piperaquine"><span lang="en" dir="auto">piperaquine</span></a></span>）</span></span></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">複方劑</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="固定劑量（共製劑）ACTs" scope="row" class="navbox-group" style="width:1%">固定劑量<br />（共製劑）<br /><a href="/wiki/%E9%9D%92%E8%92%BF%E7%B4%A0" title="青蒿素">ACTs</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%A4%87%E6%96%B9%E8%92%BF%E7%94%B2%E9%86%9A" title="複方蒿甲醚">蒿甲醚/苯芴醇</a><sup>#</sup></li> <li><span class="ilh-all" data-orig-title="青蒿氧烷" data-lang-code="en" data-lang-name="英语" data-foreign-title="arterolane"><span class="ilh-page"><a href="/w/index.php?title=%E9%9D%92%E8%92%BF%E6%B0%A7%E7%83%B7&action=edit&redlink=1" class="new" title="青蒿氧烷（页面不存在）">青蒿氧烷</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/arterolane" class="extiw" title="en:arterolane"><span lang="en" dir="auto">arterolane</span></a></span>）</span></span>/哌喹</li> <li><span class="ilh-all" data-orig-title="青蒿琥酯/阿莫地喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="artesunate/amodiaquine"><span class="ilh-page"><a href="/w/index.php?title=%E9%9D%92%E8%92%BF%E7%90%A5%E9%85%AF/%E9%98%BF%E8%8E%AB%E5%9C%B0%E5%96%B9&action=edit&redlink=1" class="new" title="青蒿琥酯/阿莫地喹（页面不存在）">青蒿琥酯/阿莫地喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/artesunate/amodiaquine" class="extiw" title="en:artesunate/amodiaquine"><span lang="en" dir="auto">artesunate/amodiaquine</span></a></span>）</span></span>（ASAQ）</li> <li><span class="ilh-all" data-orig-title="青蒿琥酯/甲氟喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="artesunate/mefloquine"><span class="ilh-page"><a href="/w/index.php?title=%E9%9D%92%E8%92%BF%E7%90%A5%E9%85%AF/%E7%94%B2%E6%B0%9F%E5%96%B9&action=edit&redlink=1" class="new" title="青蒿琥酯/甲氟喹（页面不存在）">青蒿琥酯/甲氟喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/artesunate/mefloquine" class="extiw" title="en:artesunate/mefloquine"><span lang="en" dir="auto">artesunate/mefloquine</span></a></span>）</span></span>（ASMQ）</li> <li><a href="/wiki/%E9%9D%92%E8%92%BF%E7%90%A5%E9%85%AF/%E5%92%AF%E8%90%98%E5%95%B6" title="青蒿琥酯/咯萘啶">青蒿琥酯/咯萘啶</a></li> <li><span class="ilh-all" data-orig-title="雙氫青蒿素/哌喹" data-lang-code="en" data-lang-name="英语" data-foreign-title="dihydroartemisinin/piperaquine"><span class="ilh-page"><a href="/w/index.php?title=%E9%9B%99%E6%B0%AB%E9%9D%92%E8%92%BF%E7%B4%A0/%E5%93%8C%E5%96%B9&action=edit&redlink=1" class="new" title="雙氫青蒿素/哌喹（页面不存在）">雙氫青蒿素/哌喹</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/dihydroartemisinin/piperaquine" class="extiw" title="en:dihydroartemisinin/piperaquine"><span lang="en" dir="auto">dihydroartemisinin/piperaquine</span></a></span>）</span></span></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其它複方劑<br />（非共製劑）</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li>青蒿琥酯/甲氟喹</li> <li>青蒿琥酯/ SP</li> <li>奎寧/克林黴素</li> <li>奎寧/多西環素</li> <li>奎寧/四環素</li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="ilh-all" data-orig-title="巴貝斯原蟲病" data-lang-code="en" data-lang-name="英语" data-foreign-title="Babesiosis"><span class="ilh-page"><a href="/w/index.php?title=%E5%B7%B4%E8%B2%9D%E6%96%AF%E5%8E%9F%E8%9F%B2%E7%97%85&action=edit&redlink=1" class="new" title="巴貝斯原蟲病（页面不存在）">巴貝斯原蟲病</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Babesiosis" class="extiw" title="en:Babesiosis"><span lang="en" dir="auto">Babesiosis</span></a></span>）</span></span><br />（焦蟲症）</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%85%8B%E6%9E%97%E9%BB%B4%E7%B4%A0" title="克林黴素">克林黴素</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BA%A4%E6%AF%9B%E8%99%AB" title="纤毛虫">纤毛虫</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><span class="ilh-all" data-orig-title="結腸小袋纖毛蟲病" data-lang-code="en" data-lang-name="英语" data-foreign-title="Balantidiasis"><span class="ilh-page"><a href="/w/index.php?title=%E7%B5%90%E8%85%B8%E5%B0%8F%E8%A2%8B%E7%BA%96%E6%AF%9B%E8%9F%B2%E7%97%85&action=edit&redlink=1" class="new" title="結腸小袋纖毛蟲病（页面不存在）">結腸小袋纖毛蟲病</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Balantidiasis" class="extiw" title="en:Balantidiasis"><span lang="en" dir="auto">Balantidiasis</span></a></span>）</span></span>：<a href="/wiki/%E5%9B%9B%E7%92%B0%E9%BB%B4%E7%B4%A0" title="四環黴素">四環黴素</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E4%B8%8D%E7%AD%89%E9%9E%AD%E6%AF%9B%E9%A1%9E" title="不等鞭毛類">不等鞭毛類</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><span class="ilh-all" data-orig-title="芽囊原蟲" data-lang-code="en" data-lang-name="英语" data-foreign-title="Blastocystosis"><span class="ilh-page"><a href="/w/index.php?title=%E8%8A%BD%E5%9B%8A%E5%8E%9F%E8%9F%B2&action=edit&redlink=1" class="new" title="芽囊原蟲（页面不存在）">芽囊原蟲</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Blastocystosis" class="extiw" title="en:Blastocystosis"><span lang="en" dir="auto">Blastocystosis</span></a></span>）</span></span>：<a href="/wiki/%E7%94%B2%E7%A1%9D%E5%94%91" title="甲硝唑">甲硝唑</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background：transparent; padding：0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/%E4%B8%96%E7%95%8C%E5%8D%AB%E7%94%9F%E7%BB%84%E7%BB%87%E5%9F%BA%E6%9C%AC%E8%8D%AF%E7%89%A9%E6%A0%87%E5%87%86%E6%B8%85%E5%8D%95" title="世界卫生组织基本药物标准清单">世卫基本药物（WHO-EM）</a></li> <li><sup>‡</sup>从市场<a href="/wiki/%E6%92%A4%E5%9B%9E%E8%8D%AF%E5%93%81%E5%88%97%E8%A1%A8" title="撤回药品列表">撤回</a></li> <li><sup>†</sup><a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97" title="臨床試驗">臨床試驗</a><a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97#Ⅲ期临床试验" title="臨床試驗">第三階段</a></li> <li><sup>§</sup>臨床試驗<a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97#Ⅱ期临床试验" title="臨床試驗">未到第三階段</a></li></ul> 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