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urinary catheters</title> <meta name="description" content="Search results for: indwelling urinary catheters"> <meta name="keywords" content="indwelling urinary catheters"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="indwelling urinary catheters"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 277</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: indwelling urinary catheters</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">277</span> Post-bladder Catheter Infection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahla%20Azimi">Mahla Azimi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Post-bladder catheter infection is a common and significant healthcare-associated infection that affects individuals with indwelling urinary catheters. These infections can lead to various complications, including urinary tract infections (UTIs), bacteremia, sepsis, and increased morbidity and mortality rates. This article aims to provide a comprehensive review of post-bladder catheter infections, including their causes, risk factors, clinical presentation, diagnosis, treatment options, and preventive measures. Causes and Risk Factors: Post-bladder catheter infections primarily occur due to the colonization of microorganisms on the surface of the urinary catheter. The most common pathogens involved are Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Enterococcus species. Several risk factors contribute to the development of these infections, such as prolonged catheterization duration, improper insertion technique, poor hygiene practices during catheter care, compromised immune system function in patients with underlying conditions or immunosuppressive therapy. Clinical Presentation: Patients with post-bladder catheter infections may present with symptoms such as fever, chills, malaise, suprapubic pain or tenderness, and cloudy or foul-smelling urine. In severe cases or when left untreated for an extended period of time, patients may develop more severe symptoms like hematuria or signs of systemic infection. Diagnosis: The diagnosis of post-bladder catheter infection involves a combination of clinical evaluation and laboratory investigations. Urinalysis is crucial in identifying pyuria (presence of white blood cells) and bacteriuria (presence of bacteria). A urine culture is performed to identify the causative organism(s) and determine its antibiotic susceptibility profile. Treatment Options: Prompt initiation of appropriate antibiotic therapy is essential in managing post-bladder catheter infections. Empirical treatment should cover common pathogens until culture results are available. The choice of antibiotics should be guided by local antibiogram data to ensure optimal therapy. In some cases, catheter removal may be necessary, especially if the infection is recurrent or associated with severe complications. Preventive Measures: Prevention plays a vital role in reducing the incidence of post-bladder catheter infections. Strategies include proper hand hygiene, aseptic technique during catheter insertion and care, regular catheter maintenance, and timely removal of unnecessary catheters. Healthcare professionals should also promote patient education regarding self-care practices and signs of infection. Conclusion: Post-bladder catheter infections are a significant healthcare concern that can lead to severe complications and increased healthcare costs. Early recognition, appropriate diagnosis, and prompt treatment are crucial in managing these infections effectively. Implementing preventive measures can significantly reduce the incidence of post-bladder catheter infections and improve patient outcomes. Further research is needed to explore novel strategies for prevention and management in this field. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=post-bladder%20catheter%20infection" title="post-bladder catheter infection">post-bladder catheter infection</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title=" urinary tract infection"> urinary tract infection</a>, <a href="https://publications.waset.org/abstracts/search?q=bacteriuria" title=" bacteriuria"> bacteriuria</a>, <a href="https://publications.waset.org/abstracts/search?q=indwelling%20urinary%20catheters" title=" indwelling urinary catheters"> indwelling urinary catheters</a>, <a href="https://publications.waset.org/abstracts/search?q=prevention" title=" prevention"> prevention</a> </p> <a href="https://publications.waset.org/abstracts/170185/post-bladder-catheter-infection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/170185.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">81</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">276</span> Study on the Relative Factors of Introducing Table Vinegar in Reducing Urinary Tract Infection in Patients with Long-Term Indwelling Catheter</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yu-Ju%20Hsieh">Yu-Ju Hsieh</a>, <a href="https://publications.waset.org/abstracts/search?q=Lin-Hung%20Lin"> Lin-Hung Lin</a>, <a href="https://publications.waset.org/abstracts/search?q=Wen-Hui%20Chang"> Wen-Hui Chang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study was designed as an interventional research and intended to validate whether the introduction of drinking vinegar every day can reduce and even prevent urinary tract infection in Taiwan home stayed disabilities who using indwelling catheter. The data was collected from the subjects who have received home care case at northern Taiwan, according to the questionnaire and a medical records retroactive methodology, the subjects were informed and consent to drink 15ml of table vinegar in a daily diet, and through routine urine testing and culture study. Home care nurses would assist collecting urine at the point of before and after a meal from total 35 studied subjects per month, and total collected 4 times for testing. The results showed that when the average age of study subjects was 65.46 years and catheter indwelling time was 15 years, drinking table vinegar could inhibit the activity of E. coli O157: H7 and reduce its breeding. Before drinking table vinegar daily, the subjects’ urine pH value was 7.0-8.0, and the average was 7.5, and the urine PH value dropped to 6.5 after drinking table vinegar for a month. There were two purple urine cases whose urine were changed from purple to normal color after two weeks of drinking, and the protein and bacteria values of urine gradually improved. Urine smell unpleasant before attending to this study, and the symptom improved significantly only after 1 week, and the urine smell returned to normal ammonia and became clean after 1 month later. None of these subjects received treatment in a hospital due to urinary tract infection, and there were no signs of bleeding in all cases during this study. The subjects of this study are chronic patients with a long-term bedridden catheterization; drinking cranberry juice is an economic burden for them, and also highly prohibited for diabetes patients. By adapting to use cheaper table vinegar to acidified urine and improve its smell and ease Purple Urine Syndrome, to furthermore, proven urinary tract infection, it can also to reduce the financial burden on families, the cost of social resources and the rate of re-admission. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=table%20vinegar" title="table vinegar">table vinegar</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title=" urinary tract infection"> urinary tract infection</a>, <a href="https://publications.waset.org/abstracts/search?q=disability%20patients" title=" disability patients"> disability patients</a>, <a href="https://publications.waset.org/abstracts/search?q=long-term%20indwelling%20catheter" title=" long-term indwelling catheter"> long-term indwelling catheter</a> </p> <a href="https://publications.waset.org/abstracts/84869/study-on-the-relative-factors-of-introducing-table-vinegar-in-reducing-urinary-tract-infection-in-patients-with-long-term-indwelling-catheter" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84869.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">260</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">275</span> Effect of Ethanol and Betadine on the Preformed Biofilm of Staphylococcus Aureus Isolated from Urinary Catheter</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kara%20Terki%20Ibtissem">Kara Terki Ibtissem</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassaine%20Hafida"> Hassaine Hafida</a>, <a href="https://publications.waset.org/abstracts/search?q=Bellifa%20Samia"> Bellifa Samia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Staphylococcus aureus is one of the species that are most frequently isolated from urinary catheters. The ability to produce a biofilm is an important step in the pathogenesis of these staphylococci; biofilm formation is strongly dependent on the environmental conditions it also depends on the different parameters these biofilms are subjected to. Antiseptics, including ethanol and betadine, are used in clinical practice for disinfection and infection prevention. Recent studies, however, demonstrate that disinfectants may enhance biofilm production in Staphylococci. Methods: In this study, 48 staphylococcus aureus isolated from urinary catheters at the University Hospital Center of Sidi Bel Abbes (in Northwestern Algeria) were analyzed to detect the formation of biofilm by culture on Red Congo Agar (RCA), the Tube Method (TM) and tissue Culture Plate (TCP) techniques, this last was also used to investigate the effect of ethanol and Betadine on the preformed biofilm In a second time to know which environment is most favorable to the formation of the biofilm we perform a statistical test based on the student test by the software R. Results: It has been found that 23 strains produced a bacterial slime on the Congo red medium, 5 strains produced a biofilm by the tube method, 2 of which are highly productive. In addition, 7 strains produced a biofilm on polystyrene micro-plates; this number was higher in the presence of ethanol 70% and ethanol 90% with 19 and 11 biofilm-producing strains, respectively. On the other hand, no biofilm was formed in the presence of Betadine. Conclusion: It is important to examine the response of biofilms following an imposed external constraint, such as disinfectants, in order to develop new strategies to combat bacterial biofilms but also to better control their formation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=staphylococcus%20aureus" title="staphylococcus aureus">staphylococcus aureus</a>, <a href="https://publications.waset.org/abstracts/search?q=biofilm" title=" biofilm"> biofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20catheter" title=" urinary catheter"> urinary catheter</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanol" title=" ethanol"> ethanol</a> </p> <a href="https://publications.waset.org/abstracts/184021/effect-of-ethanol-and-betadine-on-the-preformed-biofilm-of-staphylococcus-aureus-isolated-from-urinary-catheter" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184021.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">274</span> Study on Reusable, Non Adhesive Silicone Male External Catheter: Clinical Proof of Study and Quality Improvement Project</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Venkata%20Buddharaju">Venkata Buddharaju</a>, <a href="https://publications.waset.org/abstracts/search?q=Irene%20Mccarron"> Irene Mccarron</a>, <a href="https://publications.waset.org/abstracts/search?q=Hazel%20Alba"> Hazel Alba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Male external catheters (MECs) are commonly used to collect and drain urine. MECs are increasingly used in acute care, long-term acute care hospitals, and nursing facilities, and in other patients as an alternative to invasive urinary catheters to reduce catheter-associated urinary tract infections (CAUTI).MECs are also used to avoid the need for incontinence pads and diapers. Most of the Male External Catheters are held in place by skin adhesive, with the exception of a few, which uses a foam strap clamp around the penile shaft. The adhesive condom catheters typically stay for 24 hours or less. It is also a common practice that extra skin adhesive tape is wrapped around the condom catheter for additional security of the device. The fixed nature of the adhesive will not allow the normal skin expansion of penile size over time. The adhesive can cause skin irritation, redness, erosion, and skin damage. Acanthus condom catheter (ACC) is a patented, specially designed, stretchable silicone catheter without adhesive, adapts to the size and contour of the penis. It is held in place with a single elastic strap that wraps around the lower back and tied to the opposite catheter ring holescriss cross. It can be reused for up to 5 days on the same patient after daily cleaning and washingpotentially reducing cost. Methods: The study was conducted from September 17th to October 8th, 2020. The nursing staff was educated and trained on how to use and reuse the catheter. After identifying five (5) appropriate patients, the catheter was placed and maintained by nursing staff. The data on the ease of use, leak, and skin damage were collected and reported by nurses to the nursing education department of the hospital for analysis. Setting: RML Chicago, long-term acute care hospital, an affiliate of Loyola University Medical Center, Chicago, IL USA. Results: The data showed that the catheter was easy to apply, remove, wash and reuse, without skin problems or urine infections. One patient had used for 16 days after wash, reuse, and replacement without any urine leak or skin issues. A minimal leak was observed on two patients. Conclusion: Acanthus condom catheter was easy to use, functioned well with minimal or no leak during use and reuse. The skin was intact in all patients studied. There were no urinary tract infections in any of the studied patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CAUTI" title="CAUTI">CAUTI</a>, <a href="https://publications.waset.org/abstracts/search?q=male%20external%20catheter" title=" male external catheter"> male external catheter</a>, <a href="https://publications.waset.org/abstracts/search?q=reusable" title=" reusable"> reusable</a>, <a href="https://publications.waset.org/abstracts/search?q=skin%20adhesive" title=" skin adhesive"> skin adhesive</a> </p> <a href="https://publications.waset.org/abstracts/137314/study-on-reusable-non-adhesive-silicone-male-external-catheter-clinical-proof-of-study-and-quality-improvement-project" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137314.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">106</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">273</span> Central Line Stock and Use Audit in Adult Patients: A Quality Improvement Project on Central Venous Catheter Standardisation Across Hospital Departments</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gregor%20Moncrieff">Gregor Moncrieff</a>, <a href="https://publications.waset.org/abstracts/search?q=Ursula%20Bahlmann"> Ursula Bahlmann</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A number of incident reports were filed from the intensive care unit with regards to adult patients admitted following operations who had a central venous catheter inserted of the incorrect length for the relevant anatomical site and catheters not compatible with pressurised injection inserted whilst in theatre. Incorrect catheter length can lead to a variety of complications and pressurised injection is a requirement for contrast enhanced computerised tomography scans. This led to several patients having a repeat procedure to insert a catheter of the correct length and also compatible with pressurised injection. This project aimed to identify the types of central venous catheters used in theatres and ensure the correct equipment would be stocked and used in future cases in accordance the existing Association of Anaesthetics of Great Britain and Northern Ireland guidelines. A questionnaire was sent out to all of the anaesthetic department in our hospital aiming to determine what types of central venous catheters were preferably used by anaesthetists and why these had been chosen. We also explored any concerns regarding introduction of standardised, pressure injectable central venous catheters to the theatre department which were already in use in other parts of the hospital and in keeping with national guidance. A total of 56 responses were collected. 64% of respondents routinely used a central venous catheter which was significantly shorter than the national recommended guidance with a further 4 different types of central venous catheters used which were different to other areas of the hospital and not pressure injectable. 75% of respondents were in agreement to standardised introduction of the pressure injectable catheters of the recommended length in accordance with national guidance. Reasons why 25% respondents were opposed to introduction of these catheters were explored and discussed. We were successfully able to introduce the standardised central catheters to the theatre department following presentation at the local anaesthetic quality and safety meeting. Reasons against introduction of the catheters were discussed and a compromise was reached that the existing catheters would continue to be stocked but would only be available on request, with a focus on encouraging use of the standardised catheters. Additional changes achieved included removing redundant catheters from the theatre stock. Ongoing data is being collected to analyse positive and negative feedback from use of the introduced catheters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=central%20venous%20catheter" title="central venous catheter">central venous catheter</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20equipment" title=" medical equipment"> medical equipment</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20safety" title=" medical safety"> medical safety</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20improvement" title=" quality improvement"> quality improvement</a> </p> <a href="https://publications.waset.org/abstracts/158656/central-line-stock-and-use-audit-in-adult-patients-a-quality-improvement-project-on-central-venous-catheter-standardisation-across-hospital-departments" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158656.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">272</span> The Training Demands of Nursing Assistants on Urinary Incontinence in Nursing Homes: A Mixed Methods Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lulu%20Liao">Lulu Liao</a>, <a href="https://publications.waset.org/abstracts/search?q=Huijing%20Chen"> Huijing Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Yinan%20Zhao"> Yinan Zhao</a>, <a href="https://publications.waset.org/abstracts/search?q=Hongting%20Ning"> Hongting Ning</a>, <a href="https://publications.waset.org/abstracts/search?q=Hui%20Feng"> Hui Feng</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Urinary tract infection rate is an important index of care quality in nursing homes. The aim of the study is to understand the nursing assistant's current knowledge and attitudes of urinary incontinence and to explore related stakeholders' viewpoint about urinary incontinence training. This explanatory sequential study used Knowledge, Practice, and Attitude Model (KAP) and Adult Learning Theories, as the conceptual framework. The researchers collected data from 509 nursing assistants in sixteen nursing homes in Hunan province in China. The questionnaire survey was to assess the knowledge and attitude of urinary incontinence of nursing assistants. On the basis of quantitative research and combined with focus group, training demands were identified, which nurse managers should adopt to improve nursing assistants’ professional practice ability in urinary incontinence. Most nursing assistants held the poor knowledge (14.0 ± 4.18) but had positive attitudes (35.5 ± 3.19) toward urinary incontinence. There was a significant positive correlation between urinary incontinence knowledge and nursing assistants' year of work and educational level, urinary incontinence attitude, and education level (p < 0.001). Despite a general awareness of the importance of prevention of urinary tract infections, not all nurse managers fully valued the training in urinary incontinence compared with daily care training. And the nursing assistants required simple education resources to equip them with skills to address problem about urinary incontinence. The variety of learning methods also highlighted the need for educational materials, and nursing assistants had shown a strong interest in online learning. Related education material should be developed to meet the learning need of nurse assistants and provide suitable training method for planned quality improvement in urinary incontinence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mixed%20methods" title="mixed methods">mixed methods</a>, <a href="https://publications.waset.org/abstracts/search?q=nursing%20assistants" title=" nursing assistants"> nursing assistants</a>, <a href="https://publications.waset.org/abstracts/search?q=nursing%20homes" title=" nursing homes"> nursing homes</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20incontinence" title=" urinary incontinence"> urinary incontinence</a> </p> <a href="https://publications.waset.org/abstracts/125430/the-training-demands-of-nursing-assistants-on-urinary-incontinence-in-nursing-homes-a-mixed-methods-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/125430.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">271</span> Findings in Vascular Catheter Cultures at the Laboratory of Microbiology of General Hospital during One Year</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20Christodoulou">P. Christodoulou</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Gerasimou"> M. Gerasimou</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Mantzoukis"> S. Mantzoukis</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Varsamis"> N. Varsamis</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Kolliopoulou"> G. Kolliopoulou</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Zotos"> N. Zotos</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Abstract— Purpose: The Intensive Care Unit (ICU) environment is conducive to the growth of microorganisms. A variety of microorganisms gain access to the intravascular area and are transported throughout the circulatory system. Therefore, examination of the catheters used in ICU patients is of paramount importance. Material and Method: The culture medium is a catheter tip, which is enriched with Tryptic soy broth (TSB). After one day of incubation, the broth is passaged in the following selective media: Blood, Mac conkey No. 2, chocolate, Mueller Hinton, Chapman, and Saboureaud agar. The above selective media is incubated for 2 days. After this period, if any number of microbial colonies is detected, gram staining is performed and then the microorganisms are identified by biochemical techniques in the automated Microscan (Siemens) system followed by a sensitivity test in the same system using the minimum inhibitory concentration (MIC) technique. The sensitivity test is verified by a Kirby Bauer test. Results: In 2017, the Microbiology Laboratory received 84 catheters from the ICU. 42 were found positive. Of these, S. epidermidis was identified at 8, A. baumannii in 10, K. pneumoniae in 6, P. aeruginosa in 6, P. mirabilis in 3, S. simulans in 1, S. haemolyticus in 4, S. aureus in 3 and S. hominis in 1. Conclusions: The results show that the placement and maintenance of the catheters in ICU patients are relatively successful, despite the unfavorable environment of the unit. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=culture" title="culture">culture</a>, <a href="https://publications.waset.org/abstracts/search?q=intensive%20care%20unit" title=" intensive care unit"> intensive care unit</a>, <a href="https://publications.waset.org/abstracts/search?q=microorganisms" title=" microorganisms"> microorganisms</a>, <a href="https://publications.waset.org/abstracts/search?q=vascular%20catheters" title=" vascular catheters"> vascular catheters</a> </p> <a href="https://publications.waset.org/abstracts/103186/findings-in-vascular-catheter-cultures-at-the-laboratory-of-microbiology-of-general-hospital-during-one-year" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/103186.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">283</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">270</span> Pathogenic Candida Biofilms Producers Involved in Healthcare Associated Infections</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ouassila%20Bekkal%20Brikci%20Benhabib">Ouassila Bekkal Brikci Benhabib</a>, <a href="https://publications.waset.org/abstracts/search?q=Zahia%20Boucherit%20Otmani"> Zahia Boucherit Otmani</a>, <a href="https://publications.waset.org/abstracts/search?q=Kebir%20Boucherit"> Kebir Boucherit</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Seghir"> A. Seghir </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The establishment of intravenous catheters in hospitalized patient is an act common in many clinical situations. These therapeutic tools, from their insertion in the body, represent gateways including fungal germs prone. The latter can generate the growth of biofilms, which can be the cause of fungal infection. Faced with this problem, we conducted a study at the University Hospital of Tlemcen in the neurosurgery unit and aims to isolate and identify Candida yeasts from intravenous catheters. Then test their ability to form biofilms. Materials and methods: 256 patient hospitalized in surgery of the hospital in west Algeria were submitted to this study. All samples were taken from peripheral venous catheters implanted for 72 hours or more days. A total of 31 isolates of Candida species were isolated. MIC and SMIC are determined at 80% inhibition by the test XTT tetrazolium measured at 490 nm. The final concentrations of antifungal agent being between 0.03 and 16 mg / ml for amphotericin B and from 0.015 to 8 mg / mL caspofungin. Results: 31 Candida species isolates from catheters including 14 Candida albicans and 17 Candida non albicans . 21 strains of all the isolates were able to form biofilms. In their form of Planktonic cells, all isolates are 100% susceptible to antifungal agents tested. However, in their state of biofilms, more isolates have become tolerant to the tested antifungals. Conclusion: Candida yeasts isolated from intravascular catheters are considered an important virulence factor in the pathogenesis of infections. Their involvement in catheter-related infections can be disastrous for their potential to generate biofilms. They survive high concentrations of antifungal where treatment failure. Pending the development of a therapeutic approach antibiofilm related to catheters, their mastery is going through: -The risk of infection prevention based on the training and awareness of medical staff, -Strict hygiene and maximum asepsis, and -The choice of material limiting microbial colonization. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=candida" title="candida">candida</a>, <a href="https://publications.waset.org/abstracts/search?q=biofilm" title=" biofilm"> biofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=hospital" title=" hospital"> hospital</a>, <a href="https://publications.waset.org/abstracts/search?q=infection" title=" infection"> infection</a>, <a href="https://publications.waset.org/abstracts/search?q=amphotericin%20B" title=" amphotericin B"> amphotericin B</a>, <a href="https://publications.waset.org/abstracts/search?q=caspofungin" title=" caspofungin"> caspofungin</a> </p> <a href="https://publications.waset.org/abstracts/31771/pathogenic-candida-biofilms-producers-involved-in-healthcare-associated-infections" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">323</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">269</span> Ethnopharmacology of Urinary Deseases in Algerian Sahara</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Sekkoum">Khaled Sekkoum</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The traditional pharmacopoeia of Algerian Sahara is very rich on vegetable drugs. The great resources and biodiversity of Algerian Sahara flora seem responsible. A survey of medicinal plants used by the local population of the south west of Algeria for the urinary disorders is reported. Sixty-three plant species belonging to thirty-three families were identified. Their botanical and local names, plant part used, mode of use and ailment treated are given. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title="medicinal plants">medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20diseases" title=" urinary diseases"> urinary diseases</a>, <a href="https://publications.waset.org/abstracts/search?q=Sahara" title=" Sahara"> Sahara</a>, <a href="https://publications.waset.org/abstracts/search?q=Algeria" title=" Algeria"> Algeria</a> </p> <a href="https://publications.waset.org/abstracts/11687/ethnopharmacology-of-urinary-deseases-in-algerian-sahara" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11687.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">334</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">268</span> Genome Sequencing and Analysis of the Spontaneous Nanosilver Resistant Bacterium Proteus mirabilis Strain scdr1</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amr%20Saeb">Amr Saeb</a>, <a href="https://publications.waset.org/abstracts/search?q=Khalid%20Al-Rubeaan"> Khalid Al-Rubeaan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Abouelhoda"> Mohamed Abouelhoda</a>, <a href="https://publications.waset.org/abstracts/search?q=Manojkumar%20Selvaraju"> Manojkumar Selvaraju</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamsa%20Tayeb"> Hamsa Tayeb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: P. mirabilis is a common uropathogenic bacterium that can cause major complications in patients with long-standing indwelling catheters or patients with urinary tract anomalies. In addition, P. mirabilis is a common cause of chronic osteomyelitis in diabetic foot ulcer (DFU) patients. Methodology: P. mirabilis SCDR1 was isolated from a diabetic ulcer patient. We examined P. mirabilis SCDR1 levels of resistance against nano-silver colloids, the commercial nano-silver and silver containing bandages and commonly used antibiotics. We utilized next generation sequencing techniques (NGS), bioinformatics, phylogenetic analysis and pathogenomics in the identification and characterization of the infectious pathogen. Results: P. mirabilis SCDR1 is a multi-drug resistant isolate that also showed high levels of resistance against nano-silver colloids, nano-silver chitosan composite and the commercially available nano-silver and silver bandages. The P. mirabilis-SCDR1 genome size is 3,815,621 bp with G+C content of 38.44%. P. mirabilis-SCDR1 genome contains a total of 3,533 genes, 3,414 coding DNA sequence genes, 11, 10, 18 rRNAs (5S, 16S, and 23S), and 76 tRNAs. Our isolate contains all the required pathogenicity and virulence factors to establish a successful infection. P. mirabilis SCDR1 isolate is a potential virulent pathogen that despite its original isolation site, wound, it can establish kidney infection and its associated complications. P. mirabilis SCDR1 contains several mechanisms for antibiotics and metals resistance including, biofilm formation, swarming mobility, efflux systems, and enzymatic detoxification. Conclusion: P. mirabilis SCDR1 is the spontaneous nano-silver resistant bacterial strain. P. mirabilis SCDR1 strain contains all reported pathogenic and virulence factors characteristic for the species. In addition, it possesses several mechanisms that may lead to the observed nano-silver resistance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Proteus%20mirabilis" title="Proteus mirabilis">Proteus mirabilis</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-drug%20resistance" title=" multi-drug resistance"> multi-drug resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=silver%20nanoparticles" title=" silver nanoparticles"> silver nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=resistance" title=" resistance"> resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=next%20generation%20sequencing%20techniques" title=" next generation sequencing techniques"> next generation sequencing techniques</a>, <a href="https://publications.waset.org/abstracts/search?q=genome%20analysis" title=" genome analysis"> genome analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=bioinformatics" title=" bioinformatics"> bioinformatics</a>, <a href="https://publications.waset.org/abstracts/search?q=phylogeny" title=" phylogeny"> phylogeny</a>, <a href="https://publications.waset.org/abstracts/search?q=pathogenomics" title=" pathogenomics"> pathogenomics</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetic%20foot%20ulcer" title=" diabetic foot ulcer"> diabetic foot ulcer</a>, <a href="https://publications.waset.org/abstracts/search?q=xenobiotics" title=" xenobiotics"> xenobiotics</a>, <a href="https://publications.waset.org/abstracts/search?q=multidrug%20resistance%20efflux" title=" multidrug resistance efflux"> multidrug resistance efflux</a>, <a href="https://publications.waset.org/abstracts/search?q=biofilm%20formation" title=" biofilm formation"> biofilm formation</a>, <a href="https://publications.waset.org/abstracts/search?q=swarming%20mobility" title=" swarming mobility"> swarming mobility</a>, <a href="https://publications.waset.org/abstracts/search?q=resistome" title=" resistome"> resistome</a>, <a href="https://publications.waset.org/abstracts/search?q=glutathione%20S-transferase" title=" glutathione S-transferase"> glutathione S-transferase</a>, <a href="https://publications.waset.org/abstracts/search?q=copper%2Fsilver%20efflux%20system" title=" copper/silver efflux system"> copper/silver efflux system</a>, <a href="https://publications.waset.org/abstracts/search?q=altruism" title=" altruism"> altruism</a> </p> <a href="https://publications.waset.org/abstracts/63286/genome-sequencing-and-analysis-of-the-spontaneous-nanosilver-resistant-bacterium-proteus-mirabilis-strain-scdr1" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63286.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">267</span> Urinary Mucosal Cryoglobulin: A Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20M.%20S.%20Shnawa">Ibrahim M. S. Shnawa</a>, <a href="https://publications.waset.org/abstracts/search?q=Naeem%20R.%20R.%20Algebory"> Naeem R. R. Algebory</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The procedure for the assessment of the urinary mucosal cryoglobulin (UMCG) is being reviewed, testified and evaluated. The major features of UMCG are rather similar to that of serum cryoglobulin. Such evident similarities are forming the reality for the existence of the UMCG. There were seven characterizing criteria useable for the identification for UMCG. Upon matching them to the Irish criteria for serum cryoglobulin, some modifications are being proposed to the 16th standards that has been formulated and built as an Irish criterion. The existence of UMCG is being reported for the first time in human chronic infectious bacterial disease. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urinary" title="urinary">urinary</a>, <a href="https://publications.waset.org/abstracts/search?q=mucosal" title=" mucosal"> mucosal</a>, <a href="https://publications.waset.org/abstracts/search?q=cryoglubulin" title=" cryoglubulin"> cryoglubulin</a>, <a href="https://publications.waset.org/abstracts/search?q=standard%20immunofixation" title=" standard immunofixation"> standard immunofixation</a> </p> <a href="https://publications.waset.org/abstracts/11194/urinary-mucosal-cryoglobulin-a-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11194.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">460</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">266</span> Lung Function, Urinary Heavy Metals And ITS Other Influencing Factors Among Community In Klang Valley</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ammar%20Amsyar%20Abdul%20Haddi">Ammar Amsyar Abdul Haddi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Hasni%20Jaafar"> Mohd Hasni Jaafar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Heavy metals are elements naturally presented in the environment that can cause adverse effect to health. But not much literature was found on effects toward lung function, where impairment of lung function may lead to various lung diseases. The objective of the study is to explore the lung function impairment, urinary heavy metal level, and its associated factors among the community in Klang valley, Malaysia. Sampling was done in Kuala Lumpur suburb public and housing areas during community events throughout March 2019 till October 2019. respondents who gave the consent were given a questionnaire to answer and was proceeded with a lung function test. Urine samples were obtained at the end of the session and sent for Inductively coupled plasma mass spectrometry (ICP-MS) analysis for heavy metal cadmium (Cd) and lead (Pb) concentration. A total of 200 samples were analysed, and of all, 52% of respondents were male, Age ranging from 18 years old to 74 years old with a mean age of 38.44. Urinary samples show that 12% of the respondent (n=22) has Cd level above than average, and 1.5 % of the respondent (n=3) has urinary Pb at an above normal level. Bivariate analysis show that there was a positive correlation between urinary Cd and urinary Pb (r= 0.309; p<0.001). Furthermore, there was a negative correlation between urinary Cd level and full vital capacity (FVC) (r=-0.202, p=0.004), Force expiratory volume at 1 second (FEV1) (r = -0.225, p=0.001), and also with Force expiratory flow between 25-75% FVC (FEF25%-75%) (r= -0.187, p=0.008). however, urinary Pb did not show any association with FVC, FEV1, FEV1/FVC, or FEF25%-75%. Multiple linear regression analysis shows that urinary Cd remained significant and negatively affect FVC% (p=0.025) and FEV1% (p=0.004) achieved from the predicted value. On top of that, other factors such as education level (p=0.013) and duration of smoking(p=0.003) may influencing both urinary Cd and performance in lung function as well, suggesting Cd as a potential mediating factor between smoking and impairment of lung function. however, there was no interaction detected between heavy metal or other influencing factor in this study. In short, there is a negative linear relationship detected between urinary Cd and lung function, and urinary Cd is likely to affects lung function in a restrictive pattern. Since smoking is also an influencing factor for urinary Cd and lung function impairment, it is highly suggested that smokers should be screened for lung function and urinary Cd level in the future for early disease prevention. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lung%20function" title="lung function">lung function</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metals" title=" heavy metals"> heavy metals</a>, <a href="https://publications.waset.org/abstracts/search?q=community" title=" community"> community</a> </p> <a href="https://publications.waset.org/abstracts/142298/lung-function-urinary-heavy-metals-and-its-other-influencing-factors-among-community-in-klang-valley" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142298.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">156</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">265</span> Endometriosis, Bladder Endometriosis (BE), Urinary Tract Endometriosis (UTE), Robotic-Assisted Surgery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Farida%20Eid">Farida Eid</a>, <a href="https://publications.waset.org/abstracts/search?q=Hala%20Nasseif"> Hala Nasseif</a>, <a href="https://publications.waset.org/abstracts/search?q=Hana%20Mokhtar"> Hana Mokhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=Labib%20Riachi"> Labib Riachi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mudhar%20Hasan"> Mudhar Hasan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bladder Endometriosis is a rare form of endometriosis and is defined as the presence of endometriotic tissue in the detrusor muscle of the bladder, either in full or partial thickness. Women typically present with dysuria, urinary frequency, hematuria, and recurrent urinary tract infections. Bladder endometriosis is typically found at the bladder base and bladder dome. Transvaginal ultrasound is considered first-line imaging, and the condition is typically managed with laparoscopic partial cystectomy. A 33-year-old nulliparous woman presented with chronic pelvic pain, severe dysmenorrhea, and metrorrhagia. The patient was previously diagnosed with bladder endometriomas two years ago with multiple recurrences. MRI revealed urinary bladder endometriosis measuring 3 x 2 x 1.5 cm. Accordingly, the patient underwent a cystoscopy-guided robotic-assisted excision of the endometriotic implant in the bladder with cystotomy and repair of the bladder mucosa. The operation was tolerated well, and the postoperative period was uneventful. Bladder Endometriosis (BE) typically presents with urinary symptoms and can be mistaken for a bladder tumor upon further imaging. The case was successfully managed with cystoscopy-guided, robotic-assisted excision and fulguration of the endometriotic implant in the bladder. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=endometriosis" title="endometriosis">endometriosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bladder%20endometriosis%20%28BE%29" title=" bladder endometriosis (BE)"> bladder endometriosis (BE)</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20endometriosis%20%28UTE%29" title=" urinary tract endometriosis (UTE)"> urinary tract endometriosis (UTE)</a>, <a href="https://publications.waset.org/abstracts/search?q=robotic-assisted%20surgery" title=" robotic-assisted surgery"> robotic-assisted surgery</a> </p> <a href="https://publications.waset.org/abstracts/189818/endometriosis-bladder-endometriosis-be-urinary-tract-endometriosis-ute-robotic-assisted-surgery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189818.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">29</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">264</span> Correction of Urinary Incontinence in Severe Spinal Canal Stenosis, Treated Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ilirian%20La%C3%A7i">Ilirian Laçi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alketa%20Spahiu"> Alketa Spahiu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ageing causes an increase in the number of patients with spinal canal stenosis. Most of the patients have back pain, leg pain, numbness of the legs, as well as urinary incontinence as a very common symptoms. Urinary incontinence impairs the quality of life. Correction of the symptom of urinary incontinence is possible in the early and adequate treatment of spinal stenosis. Methods: This study observed patients with urinary incontinence and spinal canal stenosis. These patients underwent mechanical decompression of the spinal stenosis through surgery. At the same time, these patients were observed clinically with clinical consultations. Cystoscopy and urodynamic tests were conducted at intervals of 2 and 6 months. As a result of treatment, 60% of patients did recover. The patients in this group who benefit from treatment were the patients who were early diagnosed and treated. Conclusions: An important factor in the prognosis of this pathology is the early diagnosis and treatment. The proper treatment of this pathology makes it curable in most cases. An important role in this pathology is played by the neurosurgeon. Surgery accompanied by laminotomy and mechanical decompression is the best way of treatment. Other factors that played a role in this pathology are also a large number of childbirths for women, obesity, etc. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urinary%20incontinence" title="urinary incontinence">urinary incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20life" title=" quality of life"> quality of life</a>, <a href="https://publications.waset.org/abstracts/search?q=spinal%20canal%20stenosis" title=" spinal canal stenosis"> spinal canal stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20diagnosis" title=" early diagnosis"> early diagnosis</a>, <a href="https://publications.waset.org/abstracts/search?q=treatment" title=" treatment"> treatment</a> </p> <a href="https://publications.waset.org/abstracts/152503/correction-of-urinary-incontinence-in-severe-spinal-canal-stenosis-treated-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152503.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">263</span> Greenlight Laser Prostatectomy: A Safe and Effective Day Case Option for Bladder Outlet Obstruction in the Elderly Population</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gordon%20Weight">Gordon Weight</a>, <a href="https://publications.waset.org/abstracts/search?q=Hermione%20Tsoi"> Hermione Tsoi</a>, <a href="https://publications.waset.org/abstracts/search?q=Patrick%20Cutinha"> Patrick Cutinha</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjay%20Rajpal"> Sanjay Rajpal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: Greenlight-laser prostatectomy (GLLP) is becoming a popular treatment option for bladder outlet obstruction and lower urinary tract symptoms (LUTS). In this retrospective study, we aim to explore the patient selection, perioperative morbidity, and functional outcomes of GLLP. Methods: Patients who underwent GLLP at a UK tertiary centre between June 2018 and November 2021 were included in this study. Retrospective data covering patient demographics, perioperative parameters and postoperative outcomes were collected using the electronic records systems. Results: 305 patients were included in this study with a mean age of 73 (range 30-90) years. The most common indication (62.6%) for the procedure was patient’s wish to be free from long-term catheters (LTC) or intermittent catheterisation (ISC), followed by failed medical therapy for LUTS (36.4%). 84.6% of patients had an ASA ≥2, and 32.1% took anticoagulant or antiplatelet therapy. Inpatient stays were minimal, with the majority (68.2%) of patients were performed as day case, and only 10.5% of patients requiring more than a single night admission. The 3-month readmission rate was 10.8%, with the most common causes being haematuria and urinary-tract infection. The successful TWOC rate at follow up was 91.2%. Amongst the 19 patients who failed TWOC, 14 had LTC prior to the procedure and 4 had been performing ISC. Conclusions: Our study shows that GLLP is a safe and effective day case treatment and can be suitable for elderly and comorbid patients. Patients requiring LTC or ISC pre-operatively should be counselled carefully about the risk of not being catheter-free post procedure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urology" title="urology">urology</a>, <a href="https://publications.waset.org/abstracts/search?q=endourology" title=" endourology"> endourology</a>, <a href="https://publications.waset.org/abstracts/search?q=prostate" title=" prostate"> prostate</a>, <a href="https://publications.waset.org/abstracts/search?q=bladder%20outlet%20obstruction" title=" bladder outlet obstruction"> bladder outlet obstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=laser" title=" laser"> laser</a> </p> <a href="https://publications.waset.org/abstracts/164029/greenlight-laser-prostatectomy-a-safe-and-effective-day-case-option-for-bladder-outlet-obstruction-in-the-elderly-population" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/164029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">68</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">262</span> Association between Levels of Volatile Organic Compound Metabolites and Cigarette Smoking-Related Urothelial Carcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chi-Jung%20Chung">Chi-Jung Chung</a>, <a href="https://publications.waset.org/abstracts/search?q=Chao-Hsiang%20Chang"> Chao-Hsiang Chang</a>, <a href="https://publications.waset.org/abstracts/search?q=Chiu-Shong%20Liu"> Chiu-Shong Liu</a>, <a href="https://publications.waset.org/abstracts/search?q=Sheng-Wei%20Li"> Sheng-Wei Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Mu-Chi%20Chung"> Mu-Chi Chung</a>, <a href="https://publications.waset.org/abstracts/search?q=Ting-Jie%20Wen"> Ting-Jie Wen</a>, <a href="https://publications.waset.org/abstracts/search?q=Hui-Ling%20Lee"> Hui-Ling Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cigarette smoke contains volatile organic compounds (VOCs), such as acrylamide, 1,3-butadiene, and benzene. This study aimed to explore the associations between the urinary levels of cotinine and VOC metabolites and the risk of urothelial carcinoma (UC). A hospital-based case–control study involving two groups matched on the basis of age ( ± 3 years) and gender was designed. UC was clinically diagnosed through urological examinations and pathologically verified. Smoking-related information was collected through questionnaires and face-to-face interviews with all study participants. Urine samples were collected for the analysis of the urinary levels of VOC metabolites, cotinine, and 8-hydroxydeoxygua- nosine (8-OHdG), which was selected as a proxy of oxidative stress. Multiple logistic regressions were applied to estimate the risk of UC. The urinary cotinine and 8-OHdG levels of the UC group were higher than those of the control group. The urinary levels of VOC metabolites, including N-acetyl-S-(2-carbamoylethyl)-L-cysteine (AAMA), N- acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine, N-acetyl-S- (4- hydroxy-2-buten-1-yl)-Lcysteine-3, trans, trans-muconic acid (t,t- MA), and S-phenylmercapturic acid (SPMA) increased as the urinary levels of cotinine increased. Relevant dose-response relationships between the risk of UC risk and the urinary levels of AAMA , t,t-MA, SPMA, and 8-OHdG were found after adjusting for potential risk factors. The UC risk of participants with high urinary levels of cotinine, AAMA, t,t-MA, SPMA, and 8-OHdG were 3.5–6-fold higher than those of other participants. Increased urinary levels of VOC metabolites were associated with smoking-related UC risk. The development of UC should be explored in large-scale in vitro or in vivo studies with the repeated measurement of VOC metabolites. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=volatile%20organic%20compound" title="volatile organic compound">volatile organic compound</a>, <a href="https://publications.waset.org/abstracts/search?q=urothelial%20carcinoma" title=" urothelial carcinoma"> urothelial carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=cotinine" title=" cotinine"> cotinine</a>, <a href="https://publications.waset.org/abstracts/search?q=8-hydroxydeoxyguanosine" title=" 8-hydroxydeoxyguanosine"> 8-hydroxydeoxyguanosine</a> </p> <a href="https://publications.waset.org/abstracts/102848/association-between-levels-of-volatile-organic-compound-metabolites-and-cigarette-smoking-related-urothelial-carcinoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/102848.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">261</span> An Investigation of Tetraspanin Proteins’ Role in UPEC Infection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fawzyah%20Albaldi">Fawzyah Albaldi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Urinary tract infections (UTIs) are the most prevalent of infectious diseases and > 80% are caused by uropathogenic E. coli (UPEC). Infection occurs following adhesion to urothelial plaques on bladder epithelial cells, whose major protein constituent are the uroplakins (UPs). Two of the four uroplakins (UPIa and UPIb) are members of the tetraspanin superfamily. The UPEC adhesin FimH is known to interact directly with UPIa. Tetraspanins are a diverse family of transmembrane proteins that generally act as “molecular organizers” by binding different proteins and lipids to form tetraspanin enriched microdomains (TEMs). Previous work by our group has shown that TEMs are involved in the adhesion of many pathogenic bacteria to human cells. Adhesion can be blocked by tetraspanin-derived synthetic peptides, suggesting that tetraspanins may be valuable drug targets. In this study, we investigate the role of tetraspanins in UPEC adherence to bladder epithelial cells. Human bladder cancer cell lines (T24, 5637, RT4), commonly used as in-vitro models to investigate UPEC infection, along with primary human bladder cells, were used in this project. The aim was to establish a model for UPEC adhesion/infection with the objective of evaluating the impact of tetraspanin-derived reagents on this process. Such reagents could reduce the progression of UTI, particularly in patients with indwelling catheters. Tetraspanin expression on the bladder cells was investigated by q-PCR and flow cytometry, with CD9 and CD81 generally highly expressed. Interestingly, despite these cell lines being used by other groups to investigate FimH antagonists, uroplakin proteins (UPIa, UPIb and UPIII) were poorly expressed at the cell surface, although some were present intracellularly. Attempts were made to differentiate the cell lines, to induce cell surface expression of these UPs, but these were largely unsuccessful. Pre-treatment of bladder epithelial cells with anti-CD9 monoclonal antibody significantly decreased UPEC infection, whilst anti-CD81 had no effects. A short (15aa) synthetic peptide corresponding to the large extracellular region (EC2) of CD9 also significantly reduced UPEC adherence. Furthermore, we demonstrated specific binding of that fluorescently tagged peptide to the cells. CD9 is known to associate with a number of heparan sulphate proteoglycans (HSPGs) that have also been implicated in bacterial adhesion. Here, we demonstrated that unfractionated heparin (UFH)and heparin analogs significantly inhibited UPEC adhesion to RT4 cells, as did pre-treatment of the cells with heparinases. Pre-treatment with chondroitin sulphate (CS) and chondroitinase also significantly decreased UPEC adherence to RT4 cells. This study may shed light on a common pathogenicity mechanism involving the organisation of HSPGs by tetraspanins. In summary, although we determined that the bladder cell lines were not suitable to investigate the role of uroplakins in UPEC adhesion, we demonstrated roles for CD9 and cell surface proteoglycans in this interaction. Agents that target these may be useful in treating/preventing UTIs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=UTIs" title="UTIs">UTIs</a>, <a href="https://publications.waset.org/abstracts/search?q=tspan" title=" tspan"> tspan</a>, <a href="https://publications.waset.org/abstracts/search?q=uroplakins" title=" uroplakins"> uroplakins</a>, <a href="https://publications.waset.org/abstracts/search?q=CD9" title=" CD9"> CD9</a> </p> <a href="https://publications.waset.org/abstracts/146875/an-investigation-of-tetraspanin-proteins-role-in-upec-infection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146875.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">103</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">260</span> Relation of Urinary Microalbumin with Glycosylated Hemoglobin (HbA1c) and Duration of Type 2 Diabetes Mellitus (T2DM) in Selected Male and Female Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Junaid%20Mahmood%20Alam">Junaid Mahmood Alam</a>, <a href="https://publications.waset.org/abstracts/search?q=Howarh%20Humaira%20Ali"> Howarh Humaira Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Ishrat%20Sultana"> Ishrat Sultana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Long term irregularity in the glycemic state, especially in Type 2 diabetes mellitus (T2DM) patients, depicted by higher levels of HbA1c, is noted to be correlated with the development of microalbuminuria. The aim of the current study is to investigate the association of urinary microalbumin with HbA1c and with duration of diabetes mellitus in selected male and female T2DM patients. This cross-sectional study was carried out in a total of 70 patients, thirty-five each male and females with diagnosed T2DM, within the age group of 35-60 years. Biochemical parameters of urea, creatinine, urinary microalbumin, HbA1c, fasting blood glucose and post- parendial blood glucose were determined by standard methods. Data was statistically examined by student’s t-test and Pearson’s correlation. Results showed that comparison of healthy control subjects with both male and female T2DM patients depicted significantly elevated levels of all parameters in (P < 0.05 to P < 0.001). Comparison of duration of T2DM with the existence of urinary microalbumin was moderately significant (P < 0.05) when duration was less than 4 years, significant (P < 0.01) with duration of 4-6 years and markedly significant (P < 0.001) with duration of more than 6 years. It is concluded that in male and female T2DM patients, duration of DM as well as poor glycemic control, depicted by higher levels of HbA1c is significantly correlated with elevated levels of urinary microalbumin. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=type%202%20diabetes%20mellitus" title="type 2 diabetes mellitus">type 2 diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=glycosylated%20hemoglobin" title=" glycosylated hemoglobin"> glycosylated hemoglobin</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20microalbumin" title=" urinary microalbumin"> urinary microalbumin</a>, <a href="https://publications.waset.org/abstracts/search?q=T2DM" title=" T2DM"> T2DM</a>, <a href="https://publications.waset.org/abstracts/search?q=HbA1c" title=" HbA1c"> HbA1c</a> </p> <a href="https://publications.waset.org/abstracts/45579/relation-of-urinary-microalbumin-with-glycosylated-hemoglobin-hba1c-and-duration-of-type-2-diabetes-mellitus-t2dm-in-selected-male-and-female-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45579.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">259</span> Effectiveness of Cranberry Ingesting for Prevention of Urinary Tract Infection: A Systematic Review and Meta-Analysis of Randomized Controlled Trials</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yu-Chieh%20Huang">Yu-Chieh Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Pei-Shih%20Chen"> Pei-Shih Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Tao-Hsin%20Tung"> Tao-Hsin Tung</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Urinary tract infection is the most common bacterial infection to our best knowledge. Objective: This study is to investigate whether cranberry ingesting could improve the urinary tract infection. Methods: We searched the PubMed and Cochrane Library for relevant randomized controlled trials without language limitations between 9 March 1994 and June 30, 2017, with a priori defined inclusion and exclusion criteria. The search terms included (cranberry OR Vaccinium macrocarpon OR Vaccinium oxy-coccus OR Vaccinium microcarpum OR Vaccinium erythrocarpum OR Vaccinium) AND (urinary tract infection OR bacteriuria OR pyuria) AND (effect OR effective-ness OR efficacy) AND (random OR randomized). Results: There were 26 studies met the selection criteria included among 4709 eligible participants. We analyzed all trials in meta-analysis. The random-effects pooled risk ratio (RR) for the group using cranberry versus using placebo was 0.75; 95%CI[0.63, 0.880]; p-value=0.0002) and heterogeneity was 56%. Furthermore, we divided the subjects into different subgroup to analysis. Ingesting cranberry seemed to be more effective in some subgroups, including the patients with recurrent UTI (RR, 0.71; 95%CI[0.54,0.93]; p-value=0.002) (I²= 65%) and female population (RR, 0.73, 95%CI[0.58,0.92]; p-value=0.002) (I²= 59%). The prevention effect was not different between cranberry and trimethoprim (RR, 1.25, 95%CI[0.67, 2.33]; p-value=0.49) (I²= 68%). No matter the forms of cranberry were capsules or juice, the efficacy was useful. Conclusions: It is showed that cranberry ingesting is usefully associated with prevention UTI. There are more effective in prevention of UTI in some groups. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cranberry" title="cranberry">cranberry</a>, <a href="https://publications.waset.org/abstracts/search?q=effectiveness" title=" effectiveness"> effectiveness</a>, <a href="https://publications.waset.org/abstracts/search?q=prevention" title=" prevention"> prevention</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infect" title=" urinary tract infect"> urinary tract infect</a> </p> <a href="https://publications.waset.org/abstracts/79687/effectiveness-of-cranberry-ingesting-for-prevention-of-urinary-tract-infection-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79687.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">400</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">258</span> Efficacy of Biofeedback-Assisted Pelvic Floor Muscle Training on Postoperative Stress Urinary Incontinence</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Asmaa%20M.%20El-Bandrawy">Asmaa M. El-Bandrawy</a>, <a href="https://publications.waset.org/abstracts/search?q=Afaf%20M.%20Botla"> Afaf M. Botla</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghada%20E.%20El-Refaye"> Ghada E. El-Refaye</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20O.%20Ghareeb"> Hassan O. Ghareeb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Urinary incontinence is a common problem among adults. Its incidence increases with age and it is more frequent in women. Pelvic floor muscle training (PFMT) is the first-line therapy in the treatment of pelvic floor dysfunction (PFD) either alone or combined with biofeedback-assisted PFMT. The aim of the work: The purpose of this study is to evaluate the efficacy of biofeedback-assisted PFMT in postoperative stress urinary incontinence. Settings and Design: A single blind controlled trial design was. Methods and Material: This study was carried out in 30 volunteer patients diagnosed as severe degree of stress urinary incontinence and they were admitted to surgical treatment. They were divided randomly into two equal groups: (Group A) consisted of 15 patients who had been treated with post-operative biofeedback-assisted PFMT and home exercise program (Group B) consisted of 15 patients who had been treated with home exercise program only. Assessment of all patients in both groups (A) and (B) was carried out before and after the treatment program by measuring intra-vaginal pressure in addition to the visual analog scale. Results: At the end of the treatment program, there was a highly statistically significant difference between group (A) and group (B) in the intra-vaginal pressure and the visual analog scale favoring the group (A). Conclusion: biofeedback-assisted PFMT is an effective method for the symptomatic relief of post-operative female stress urinary incontinence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20urinary%20incontinence" title="stress urinary incontinence">stress urinary incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=pelvic%20floor%20muscles" title=" pelvic floor muscles"> pelvic floor muscles</a>, <a href="https://publications.waset.org/abstracts/search?q=pelvic%20floor%20exercises" title=" pelvic floor exercises"> pelvic floor exercises</a>, <a href="https://publications.waset.org/abstracts/search?q=biofeedback" title=" biofeedback"> biofeedback</a> </p> <a href="https://publications.waset.org/abstracts/47809/efficacy-of-biofeedback-assisted-pelvic-floor-muscle-training-on-postoperative-stress-urinary-incontinence" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47809.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">308</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">257</span> Biomechanical Perspectives on the Urinary Bladder: Insights from the Hydrostatic Skeleton Concept</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Igor%20Vishnevskyi">Igor Vishnevskyi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The urinary bladder undergoes repeated strain during its working cycle, suggesting the presence of an efficient support system, force transmission, and mechanical amplification. The concept of a "hydrostatic skeleton" (HS) could contribute to our understanding of the functional relationships among bladder constituents. Methods: A multidisciplinary literature review was conducted to identify key features of the HS and to gather evidence supporting its applicability in urinary bladder biomechanics. The collected evidence was synthesized to propose a framework for understanding the potential hydrostatic properties of the urinary bladder based on existing knowledge and HS principles. Results: Our analysis revealed similarities in biomechanical features between living fluid-filled structures and the urinary bladder. These similarities include the geodesic arrangement of fibres, the role of enclosed fluid (urine) in force transmission, prestress as a determinant of stiffness, and the ability to maintain shape integrity during various activities. From a biomechanical perspective, urine may be considered an essential component of the bladder. The hydrostatic skeleton, with its autonomy and flexibility, may provide insights for researchers involved in bladder engineering. Discussion: The concept of a hydrostatic skeleton offers a holistic perspective for understanding bladder function by considering multiple mechanical factors as a single structure with emergent properties. Incorporating viewpoints from various fields on HS can help identify how this concept applies to live fluid-filled structures or organs and reveal its broader relevance to biological systems, both natural and artificial. Conclusion: The hydrostatic skeleton (HS) design principle can be applied to the urinary bladder. Understanding the bladder as a structure with HS can be instrumental in biomechanical modelling and engineering. Further research is required to fully elucidate the cellular and molecular mechanisms underlying HS in the bladder. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydrostatic%20skeleton" title="hydrostatic skeleton">hydrostatic skeleton</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20bladder%20morphology" title=" urinary bladder morphology"> urinary bladder morphology</a>, <a href="https://publications.waset.org/abstracts/search?q=shape%20integrity" title=" shape integrity"> shape integrity</a>, <a href="https://publications.waset.org/abstracts/search?q=prestress" title=" prestress"> prestress</a>, <a href="https://publications.waset.org/abstracts/search?q=biomechanical%20modelling" title=" biomechanical modelling"> biomechanical modelling</a> </p> <a href="https://publications.waset.org/abstracts/166783/biomechanical-perspectives-on-the-urinary-bladder-insights-from-the-hydrostatic-skeleton-concept" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166783.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">256</span> Transcranial and Sacral Magnetic Stimulation as a Therapeutic Resource for Urinary Incontinence – A Brief Bibliographic Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ana%20Lucia%20Molina">Ana Lucia Molina</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique for the investigation and modulation of cortical excitability in humans. The modulation of the processing of different cortical areas can result in several areas for rehabilitation, showing great potential in the treatment of motor disorders. In the human brain, the supplementary motor area (SMA) is involved in the control of the pelvic floor muscles (MAP), where dysfunctions of these muscles can lead to urinary incontinence. Peripheral magnetic stimulation, specifically sacral magnetic stimulation, has been used as a safe and effective treatment option for patients with lower urinary tract dysfunction. A systematic literature review was carried out (Pubmed, Medline and Google academic database) without a time limit using the keywords: "transcranial magnetic stimulation", "sacral neuromodulation", and "urinary incontinence", where 11 articles attended to the inclusion criteria. Results: Thirteen articles were selected. Magnetic stimulation is a non-invasive neuromodulation technique widely used in the evaluation of cortical areas and their respective peripheral areas, as well as in the treatment of lesions of brain origin. With regard to pelvic-perineal disorders, repetitive transcranial stimulation showed significant effects in controlling urinary incontinence, as well as sacral peripheral magnetic stimulation, in addition to exerting the potential to restore bladder sphincter function. Conclusion: Data from the literature suggest that both transcranial stimulation and peripheral stimulation are non-invasive references that can be promising and effective means of treatment in pelvic and perineal disorders. More prospective and randomized studies on a larger scale are needed, adapting the most appropriate and resolving parameters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urinary%20incontinence" title="urinary incontinence">urinary incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=non-invasive%20neuromodulation" title=" non-invasive neuromodulation"> non-invasive neuromodulation</a>, <a href="https://publications.waset.org/abstracts/search?q=sacral%20neuromodulation" title=" sacral neuromodulation"> sacral neuromodulation</a>, <a href="https://publications.waset.org/abstracts/search?q=transcranial%20magnetic%20stimulation." title=" transcranial magnetic stimulation."> transcranial magnetic stimulation.</a> </p> <a href="https://publications.waset.org/abstracts/164197/transcranial-and-sacral-magnetic-stimulation-as-a-therapeutic-resource-for-urinary-incontinence-a-brief-bibliographic-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/164197.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">98</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">255</span> Urinary Exosome miR-30c-5p as a Biomarker for Early-Stage Clear Cell Renal Cell Carcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shangqing%20Song">Shangqing Song</a>, <a href="https://publications.waset.org/abstracts/search?q=Bin%20Xu"> Bin Xu</a>, <a href="https://publications.waset.org/abstracts/search?q=Yajun%20Cheng"> Yajun Cheng</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhong%20Wang"> Zhong Wang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> miRNAs derived from exosomes exist in a body fluid such as urine were regarded as potential biomarkers for various human cancers diagnosis and prognosis, as mature miRNAs can be steadily preserved by exosomes. However, its potential value in clear cell renal cell carcinoma (ccRCC) diagnosis and prognosis remains unclear. In the present study, differentially expressed miRNAs from urinal exosomes were identified by next-generation sequencing (NGS) technology. The 16 differentially expressed miRNAs were identified between ccRCC patients and healthy donors. To explore the specific diagnosis biomarker of ccRCC, we validated these urinary exosomes from 70 early-stage renal cancer patients, 30 healthy people and other urinary system cancers, including 30 early-stage prostate cancer patients and 30 early-stage bladder cancer patients by qRT-PCR. The results showed that urinary exosome miR-30c-5p could be stably amplified and meanwhile the expression of miR-30c-5p has no significant difference between other urinary system cancers and healthy control, however, expression level of miR-30c-5p in urinary exosomal of ccRCC patients was lower than healthy people and receiver operation characterization (ROC) curve showed that the area under the curve (AUC) values was 0.8192 (95% confidence interval was 0.7388-0.8996, P= 0.0000). In addition, up-regulating miR-30c-5p expression could inhibit renal cell carcinoma cells growth. Lastly, HSP5A was found as a direct target gene of miR-30c-5p. HSP5A depletion reversed the promoting effect of ccRCC growth casued by miR-30c-5p inhibitor, respectively. In conclusion, this study demonstrated that urinary exosomal miR-30c-5p is readily accessible as diagnosis biomarker of early-stage ccRCC, and miR-30c-5p might modulate the expression of HSPA5, which correlated with the progression of ccRCC. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clear%20cell%20renal%20cell%20carcinoma" title="clear cell renal cell carcinoma">clear cell renal cell carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=exosome" title=" exosome"> exosome</a>, <a href="https://publications.waset.org/abstracts/search?q=HSP5A" title=" HSP5A"> HSP5A</a>, <a href="https://publications.waset.org/abstracts/search?q=miR-30c-5p" title=" miR-30c-5p"> miR-30c-5p</a> </p> <a href="https://publications.waset.org/abstracts/93777/urinary-exosome-mir-30c-5p-as-a-biomarker-for-early-stage-clear-cell-renal-cell-carcinoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93777.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">267</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">254</span> Risk Factors for High Resistance of Ciprofloxacin Against Escherichia coli in Complicated Urinary Tract Infection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Liaqat%20Ali">Liaqat Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Khalid%20Farooq"> Khalid Farooq</a>, <a href="https://publications.waset.org/abstracts/search?q=Shafieullah%20Khan"> Shafieullah Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Nasir%20Orakzai"> Nasir Orakzai</a>, <a href="https://publications.waset.org/abstracts/search?q=Qudratullah"> Qudratullah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: To determine the risk factors for high resistance of ciprofloxacin in complicated urinary tract infections. Materials and Methods: It is an analytical study that was conducted in the department of Urology (Team ‘C’) at Institute of Kidney Diseases Hayatabad Peshawar from 1st June 2012 till 31st December 2012. Total numbers of 100 patients with complicated UTI was selected in the study. Multivariate analysis and linear regression were performed for the detection of risk factors. All the data was recorded on structured Proforma and was analyzed on SPSS version 17. Results: The mean age of the patient was 55.6 years (Range 3-82 years). 62 patients were male while 38 patients were female. 66 isolates of E-Coli were found sensitive to ciprofloxacin while 34 isolates were found Resistant for ciprofloxacin. Using multivariate analysis and linear regression, an increasing age above 50 (p=0.002) History of urinary catheterization especially for bladder outflow obstruction (p=0.001) and previous multiple use of ciprofloxacin (p=0.001) and poor brand of ciprofloxacin were found to be independent risk factors for high resistance of ciprofloxacin. Conclusion: UTI is common illness across the globe with increasing trend of antimicrobial resistance for ciprofloxacin against E Coli in complicated UTI. The risk factors for emerging resistance are increasing age, urinary catheterization and multiple use and poor brand of ciprofloxacin. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title="urinary tract infection">urinary tract infection</a>, <a href="https://publications.waset.org/abstracts/search?q=ciprofloxacin" title=" ciprofloxacin"> ciprofloxacin</a>, <a href="https://publications.waset.org/abstracts/search?q=urethral%20catheterization" title=" urethral catheterization"> urethral catheterization</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20resistance" title=" antimicrobial resistance"> antimicrobial resistance</a> </p> <a href="https://publications.waset.org/abstracts/13555/risk-factors-for-high-resistance-of-ciprofloxacin-against-escherichia-coli-in-complicated-urinary-tract-infection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13555.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">354</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">253</span> Modified Preputial Urethrostomy as a Salvage Procedure in Four Dogs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Thomas%20Giansetto">Thomas Giansetto</a>, <a href="https://publications.waset.org/abstracts/search?q=Olivier%20Broux"> Olivier Broux</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%A9raldine%20Bolen"> Géraldine Bolen</a>, <a href="https://publications.waset.org/abstracts/search?q=St%C3%A9phanie%20Claeys"> Stéphanie Claeys</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To describe a modified preputial urethrostomy in four dogs. Study design: Short case series. Animals: Four male dogs were treated by the modified preputial urethrostomy, three because of urethral stenosis, and one because of severe complications following perineal urethrostomy. Methods: Four dogs were presented for dysuria and urinary obstruction. secondary to urethral stenosis or tear. Obstruction was treated with a modified preputial urethrostomy. Results: Four dogs had resolution of dysuria with a modified preputial urethrostomy without penile amputation. None of the dogs presented signs of dysuria, urinary tract infection, or dermatitis postoperatively. Two dogs showed signs of urinary incontinence 15 days and one month postoperatively. Conclusion: The modified preputial urethrostomy resulted in a favorable prognosis and may be an alternative to prepubic urethrostomy in male dogs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urethrostomy" title="urethrostomy">urethrostomy</a>, <a href="https://publications.waset.org/abstracts/search?q=preputial" title=" preputial"> preputial</a>, <a href="https://publications.waset.org/abstracts/search?q=technique" title=" technique"> technique</a>, <a href="https://publications.waset.org/abstracts/search?q=urogenital" title=" urogenital"> urogenital</a> </p> <a href="https://publications.waset.org/abstracts/149472/modified-preputial-urethrostomy-as-a-salvage-procedure-in-four-dogs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149472.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">168</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">252</span> Protective Effect of L-Carnitine against Gentamicin-Induced Nephrotoxicity in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20F.%20Ahmed">Mohamed F. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mabruka%20S.%20Elashheb"> Mabruka S. Elashheb</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatma%20M.%20Ben%20Rabha"> Fatma M. Ben Rabha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days) , group 3: treated with L‐carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the above-mentioned parameters as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of the kidney associated with gentamicin-induced nephrotoxicity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gentamicin" title="gentamicin">gentamicin</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrotoxicity" title=" nephrotoxicity"> nephrotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=L%E2%80%90carnitine" title=" L‐carnitine"> L‐carnitine</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20disease" title=" kidney disease"> kidney disease</a> </p> <a href="https://publications.waset.org/abstracts/2809/protective-effect-of-l-carnitine-against-gentamicin-induced-nephrotoxicity-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2809.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">251</span> Antimicrobial Effects and Phytochemical Analysis of Chrysophyllum Albidum Plant Parts (Leaves, Roots and Seeds) Extracts on Bacterial Isolates from Urinary Catheters</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ebere%20Christian%20Ugochukwu">Ebere Christian Ugochukwu</a>, <a href="https://publications.waset.org/abstracts/search?q=Okafor%20Josephine"> Okafor Josephine</a>, <a href="https://publications.waset.org/abstracts/search?q=Oyawoye%20Tomisin"> Oyawoye Tomisin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The occurrence of multidrug resistance patterns that have been developed by bacteria has made it difficult to properly treat infections using standard clinical medications. Hence, the use of herbs as an alternative source of therapy is considered cheap and easily accessible to locals. This research explored the antimicrobial effects of aqueous and ethanolic extracts obtained from Chrysophyllum albidum (commonly called ‘Agbalumo’ in southwest Nigeria and ‘Udara’ in the eastern and southern parts of Nigeria) plant parts (leaves, roots and seeds) against bacteria isolated from urinary catheter tips. The following isolates were obtained; Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Proteus mirabilis, and Klebsiella aerogenes. The agar well diffusion method was used. The average percentages of antimicrobial resistance of the isolates to gentamycin were 45.5% for P. aeruginosa, 42.1% for E. coli, 46.9% for K. aerogenes, and ˃90% for other isolates. Qualitative phytochemical screening of the plant parts extracts was done using chemical test for the screening and identification of bioactive chemical constituents. The ethanolic extract mixtures (leaf, root and seed) had the greatest effect on all the isolates, with inhibition zones (IZs) ranging from 8-26 mm and MICs ranging from <16-32 mg/ml. The Potencies of the C. albidum extracts based on the IZ and MIC values were greater in the extract mixtures, followed by those in the roots. Phytochemical screening revealed that all the extracts contained phenol except for the seeds while tannins were present in all the extracts except the leaves. The activity of the ethanolic extracts of each part at high and low concentrations was greater than that of the aqueous extracts at the same concentrations (p<0.05). The acute toxicity results showed that the LD50 of the extracts was ˃5000 mg/body weight, indicating no toxicity. The antibacterial activities of the extract mixtures and roots on the isolates confirmed the use of C. albidum in folk medicine for the treatment of CAUTIs, hence indicating its antibacterial potential for use in novel antibiotic production. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antimicrobials" title="antimicrobials">antimicrobials</a>, <a href="https://publications.waset.org/abstracts/search?q=susceptibility" title=" susceptibility"> susceptibility</a>, <a href="https://publications.waset.org/abstracts/search?q=minimum%20inhibitory%20concentration" title=" minimum inhibitory concentration"> minimum inhibitory concentration</a>, <a href="https://publications.waset.org/abstracts/search?q=extracts" title=" extracts"> extracts</a> </p> <a href="https://publications.waset.org/abstracts/189605/antimicrobial-effects-and-phytochemical-analysis-of-chrysophyllum-albidum-plant-parts-leaves-roots-and-seeds-extracts-on-bacterial-isolates-from-urinary-catheters" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">29</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">250</span> Acute Phase Proteins as Biomarkers of Urinary Tract Infection (UTI) in Dairy Cattle</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wael%20El-Deeb">Wael El-Deeb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study aimed to investigate the diagnostic importance of acute phase proteins in urinary tract infection (UTI) in cattle. We describe the clinical, bacteriological and biochemical findings in 99 lactating cows. Blood and urine samples from diseased (n=84) and control healthy cows (n=15) were submitted to laboratory investigations. The urine analysis revealed hematuria and pyuria in UTI group. The isolated bacteria were E.coli (43/84) Corynebacterium spp, (31/84), Proteus spp. (6/84) and Streptococcus spp (4/84). The concentrations of Haptoglobin (Hp), serum amyloid A (SAA), α1-Acid glycoprotein (AGP), fibrinogen (Fb), total protein, albumen, and globulin were higher in cows with UTI when compared to healthy ones. Fifty-one of 84 cows with UTI were successfully treated. The levels of Hp, SAA, AGP, total protein, and globulin were associated with the odds of treatment failure. Conclusively, acute phase proteins could be used as diagnostic and prognostic biomarkers in cows with UTI. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cows" title="cows">cows</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary" title=" urinary"> urinary</a>, <a href="https://publications.waset.org/abstracts/search?q=infections" title=" infections"> infections</a>, <a href="https://publications.waset.org/abstracts/search?q=haptoglobin" title=" haptoglobin"> haptoglobin</a>, <a href="https://publications.waset.org/abstracts/search?q=serum%20Amyloid%20A" title=" serum Amyloid A"> serum Amyloid A</a> </p> <a href="https://publications.waset.org/abstracts/17849/acute-phase-proteins-as-biomarkers-of-urinary-tract-infection-uti-in-dairy-cattle" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17849.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">722</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">249</span> Urinary Neutrophil Gelatinase Associated Lipocalin as Diagnostic Biomarkers for Lupus Nephritis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lorena%20G%C3%B3Mez%20Escorcia">Lorena GóMez Escorcia</a>, <a href="https://publications.waset.org/abstracts/search?q=Gustavo%20Aroca%20Mart%C3%ADNez"> Gustavo Aroca MartíNez</a>, <a href="https://publications.waset.org/abstracts/search?q=Jose%20Luiz%20Villarreal"> Jose Luiz Villarreal</a>, <a href="https://publications.waset.org/abstracts/search?q=Elkin%20Navarro%20Quiroz"> Elkin Navarro Quiroz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lupus nephritis (LN) is a high-cost disease, occurring in about half of patients with Systemic Lupus Erythematosus (SLE). Renal biopsy constitutes the only protocol that, to date, allows a correct diagnosis of the level of renal involvement in these patients. However, this procedure can have various adverse effects such as kidney bleeding, muscle bleeding, infection, pain, among others. Therefore, the development of new diagnostic alternatives is required. The neutrophil gelatinase-associated lipocalin (NGAL) has been emerging as a novel biomarker of acute kidney injury. The aim of this study was to assess urinary NGAL levels as a marker for disease activity in patients with lupus nephritis. For this work included 50 systemic lupus erythematosus (SLE) patients, 50 with active lupus nephritis (LN), and 50 without autoimmune and renal disease as controls. TNGAL in urine samples was measured by enzyme-linked immunosorbent assay (ELISA). The results revealed that patients with kidney damage had an elevated urinary NGAL as compared to patients with lupus without kidney damage and controls (p <0.005), and the mean of uNGAL was (28.72 ± 4.53), (19.51 ± 4.72), (8.91 ± 3.37) respectively. Measurement of urinary NGAL levels showed a very good diagnostic performance for discriminating patients with Lupus nephritis from SLE without renal damage and of control individuals. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lupus%20nephritis" title="lupus nephritis">lupus nephritis</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarker" title=" biomarker"> biomarker</a>, <a href="https://publications.waset.org/abstracts/search?q=NGAL" title=" NGAL"> NGAL</a>, <a href="https://publications.waset.org/abstracts/search?q=urine%20samples" title=" urine samples"> urine samples</a> </p> <a href="https://publications.waset.org/abstracts/139650/urinary-neutrophil-gelatinase-associated-lipocalin-as-diagnostic-biomarkers-for-lupus-nephritis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/139650.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">207</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">248</span> Clinical Efficacy and Tolerability of Dropsordry™ in Spanish Perimenopausal Women with Urgency Urinary Incontinence (UUI)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20A.%20Mara%C3%B1%C3%B3n">J. A. Marañón</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Lozano%20C.%20De%20Los%20Santos"> L. Lozano C. De Los Santos</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Mart%C3%ADnez-Campesino"> L. Martínez-Campesino</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Caballero-Garrido"> E. Caballero-Garrido</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Gal%C3%A1n-Estella"> F. Galán-Estella</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Urinary incontinence (UI) is a significant health problem with considerable social and economic impact. An estimated 30% of women aged 30 to 60 years old have urinary incontinence (UI), while more than 50% of community-dwelling older women have the condition. Stress urinary incontinence and overactive bladder are the common types of incontinence The prevalence of stress and mixed (stress and urge) incontinence is higher than urge incontinence, but the latter is more likely to require treatment. In women, moderate and severe have a prevalence ranging from about 12% to 17% The objectives of this study was to examine the effect of the supplementation of tablets containing Dropsordry in women with urge urinary incontinence (UUI). Dropsordry is a novel active containing phytoestrogens from SOLGEN, the high genistin soy bean extract and pyrogallol plus polyphenols from standarized pumpkin seed extract,. The study was a single-center, not randomiized open prospective, study. 28 women with urinary incontinence ≥45 years were enrolled in this study (45-62 y. old age . Mean 52 y old). Items related to UI symptoms, were previously collected (T0) and these ítems were reviewed at the final of the study – 8 weeks. (T2). The presence of UI was previously diagnosed using the International Continence Society standards (ICS). Relationships between presence of UI and potential related factors as diabetes were also explored. Daily urinary test control was performed during the 8 weeks of treatment. Daily dosage was 1 g/ day (500 mg twice per day) from 0 to 4 week (T1), following a 500 mg/day daily intake from 4 to 8 week (T2). After eight weeks of treatment, the urgency grade score was reduced a 24,7%. The total urge episodes was reduced a 46%. Surprisingly there was no a significant change in daytime urinations (< 5%), however nocturia was reduced a 69,35%. Strenght Urinary Incontinence (SUI) was also tested showing a remarkably 52,17% reduction. Moreover the use of daily pantyliners was reduced a 66,25%. In addition, it was performed a panel test survey with quests when subjects of the study were enrolled (T0) and the same quests was performed after 8 weeks of supplementation (T2). 100% of the enrolled women fullfilled the ICIQ-SF quest (Spanish versión) and they were also questioned about the effects they noticed in response to taking the supplement and the change in quality of life. Interestingly no side effects were reported. There was a 96,2% of subjective satisfaction and a 85,8% objective score in the improvement of quality of life. CONCLUSION: the combination of High genistin isoflavones and pumpkin seed pyrogallol in Dropsordry tablets seems to be a safe and highly effective supplementation for the relieve of the urinary incontinence symptoms and a better quality of life in perimenopause women . <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=isoflavones" title="isoflavones">isoflavones</a>, <a href="https://publications.waset.org/abstracts/search?q=pumpkin" title=" pumpkin"> pumpkin</a>, <a href="https://publications.waset.org/abstracts/search?q=menopause" title=" menopause"> menopause</a>, <a href="https://publications.waset.org/abstracts/search?q=incontinence" title=" incontinence"> incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=genistin" title=" genistin"> genistin</a> </p> <a href="https://publications.waset.org/abstracts/41643/clinical-efficacy-and-tolerability-of-dropsordry-in-spanish-perimenopausal-women-with-urgency-urinary-incontinence-uui" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41643.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">405</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=indwelling%20urinary%20catheters&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=indwelling%20urinary%20catheters&page=3">3</a></li> <li class="page-item"><a class="page-link" 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