For Dementia Prevention, Sleep Quality in Midlife Matters More

<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <title>For Dementia Prevention, Sleep Quality in Midlife Matters More | UC San Francisco</title> <meta charset="utf-8" /> <meta name="description" content="Quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start." /> <meta name="abstract" content="Quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start." /> <link rel="canonical" href="https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" /> <link rel="image_src" href="https://www.ucsf.edu/sites/default/files/2023-12/actogram.jpg" /> <meta property="og:site_name" content="For Dementia Prevention, Sleep Quality in Midlife Matters More | UC San Francisco" /> <meta property="og:type" content="news" /> <meta property="og:url" content="https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" /> <meta property="og:title" content="For Dementia Prevention, Sleep Quality in Midlife Matters More" /> <meta property="og:description" content="Quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start." /> <meta property="og:image" content="https://www.ucsf.edu/sites/default/files/2023-12/actogram.jpg" /> <meta property="og:image:secure_url" content="https://www.ucsf.edu/sites/default/files/2023-12/actogram.jpg" /> <meta property="og:image:type" content="image/jpeg" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:description" content="Quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start." /> <meta name="twitter:site" content="@ucsf" /> <meta name="twitter:title" content="For Dementia Prevention, Sleep Quality in Midlife Matters More" /> <meta name="twitter:creator" content="@ucsf" /> <meta name="twitter:image" content="https://www.ucsf.edu/sites/default/files/2023-12/actogram.jpg" /> <meta name="twitter:image:alt" content="||||" /> <meta name="google-site-verification" content="rSaM6CprJQndLnVGSxg0oZ-oB85lajeVcjE1fQzK1-I" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <script type="application/ld+json">{ "@context": "https://schema.org", "@graph": [ { "@type": "NewsArticle", "headline": "For Dementia Prevention, Sleep Quality in Midlife Matters More", "name": "For Dementia Prevention, Sleep Quality in Midlife Matters More | UC San Francisco", "description": "Quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start.", "image": { "@type": "ImageObject", "representativeOfPage": "True", "url": "https://www.ucsf.edu/sites/default/files/2023-12/actogram.jpg", "width": "940", "height": "481" }, "datePublished": "2023-12-27T10:09:34-0800", "dateModified": "2023-12-27T10:09:34-0800", "author": { "@type": "Organization", "@id": "https://www.ucsf.edu/", "name": "University of California San Francisco", "url": "https://www.ucsf.edu/", "sameAs": "https://twitter.com/ucsf, https://www.facebook.com/ucsf, https://instagram.com/ucsf, https://www.youtube.com/ucsf, https://www.linkedin.com/school/ucsf", "logo": { "@type": "ImageObject", "representativeOfPage": "True", "url": "https://www.ucsf.edu/themes/custom/ucsf/assets/images/ucsf_logo_navy_for_google_structured_data.png", "width": "360", "height": "174" } }, "publisher": { "@type": "Organization", "@id": "https://www.ucsf.edu/", "name": "University of California San Francisco", "url": "https://www.ucsf.edu/", "sameAs": "https://twitter.com/ucsf, https://www.facebook.com/ucsf, https://instagram.com/ucsf, https://www.youtube.com/ucsf, https://www.linkedin.com/school/ucsf", "logo": { "@type": "ImageObject", "representativeOfPage": "True", "url": "https://www.ucsf.edu/themes/custom/ucsf/assets/images/ucsf_logo_navy_for_google_structured_data.png", "width": "360", "height": "174" } }, "mainEntityOfPage": "https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" } ] }</script> <meta itemprop="acquia_lift:content_title" content="For Dementia Prevention, Sleep Quality in Midlife Matters More" /> <meta itemprop="acquia_lift:content_type" content="article" /> <meta itemprop="acquia_lift:page_type" content="node page" /> <meta itemprop="acquia_lift:language" content="en" /> <meta itemprop="acquia_lift:content_section" content="" /> <meta itemprop="acquia_lift:content_keywords" content="" /> <meta itemprop="acquia_lift:post_id" content="426901" /> <meta itemprop="acquia_lift:content_uuid" content="5d53b81a-49cb-4cba-966f-a4fdc8955230" /> <meta itemprop="acquia_lift:published_date" content="1703700574" /> <meta itemprop="acquia_lift:persona" content="" /> <meta itemprop="acquia_lift:engagement_score" content="1" /> <meta itemprop="acquia_lift:account_id" content="UCSF" /> <meta itemprop="acquia_lift:site_id" content="ucsfedu" /> <meta itemprop="acquia_lift:liftAssetsURL" content="https://builder.lift.acquia.com" /> <meta itemprop="acquia_lift:liftDecisionAPIURL" content="https://us.perz-api.cloudservices.acquia.io" /> <meta itemprop="acquia_lift:bootstrapMode" content="auto" /> <meta itemprop="acquia_lift:contentReplacementMode" content="trusted" /> <meta itemprop="acquia_lift:apiVersion" content="v3" /> <script src="https://builder.lift.acquia.com/lift.js" async></script> <link rel="icon" href="/themes/custom/ucsf/favicon.ico" type="image/vnd.microsoft.icon" /> <link rel="preload" href="/themes/custom/ucsf/fonts/GranjonLTW01-Roman.woff2" as="font" crossorigin /> <link rel="preload" href="/themes/custom/ucsf/fonts/HelveticaNeueLTW04-45Light.woff2" as="font" crossorigin /> <link rel="preload" href="/themes/custom/ucsf/fonts/HelveticaNeueLTW04-55Roman.woff2" as="font" crossorigin /> <link rel="preload" href="/themes/custom/ucsf/fonts/HelveticaNeueLTW04-56Italic.woff2" as="font" crossorigin /> <link rel="preload" href="/themes/custom/ucsf/fonts/HelveticaNeueLTW04-65Medium.woff2" as="font" crossorigin /> <link rel="preload" href="/themes/custom/ucsf/fonts/HelveticaNeueLTW06-75Bold.woff2" as="font" crossorigin /> <script src="/sites/default/files/google_tag/primary/google_tag.script.js?snbnwj" defer></script> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_1M6X16-toc9kPsDUV7f1fRiXXjEbDp_DX8NYskiSeKQ.css?delta=0&language=en&theme=ucsf&include=eJxlkFFuxDAIRC_krj96IIvYbEIXm8jgpO7p691E2kb9QehpYAbiAxOZ1NA_jcLKbaaifscpSl6lYDF1CQwYOlY_4QIbSVWnEgk45DENgak81P9HN1swo9OuhtlPoOgig2q_9BlVYUZ1USr6IjUD0w-6FvXuZ5YJ2HVp1iYMMzBj7Sf-UOvDaHZqYKRGUX2qbQW-vYnbCHf1r3rLkhrjBcEXfB9eyCNtsXCHhFeiu4guB3uWAHWsZgwm67AII3nFaGFBSM88l2HZsDKsIaENDUn5s-f8GUUpeuJCQ6_AilDj4RkgyTgeCnB_HfmGv-lmsOQ" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_d3zMBqhbzEuXhe0NGNKEjFfiJ6wRrce_6DpOq2twhpc.css?delta=1&language=en&theme=ucsf&include=eJxlkFFuxDAIRC_krj96IIvYbEIXm8jgpO7p691E2kb9QehpYAbiAxOZ1NA_jcLKbaaifscpSl6lYDF1CQwYOlY_4QIbSVWnEgk45DENgak81P9HN1swo9OuhtlPoOgig2q_9BlVYUZ1USr6IjUD0w-6FvXuZ5YJ2HVp1iYMMzBj7Sf-UOvDaHZqYKRGUX2qbQW-vYnbCHf1r3rLkhrjBcEXfB9eyCNtsXCHhFeiu4guB3uWAHWsZgwm67AII3nFaGFBSM88l2HZsDKsIaENDUn5s-f8GUUpeuJCQ6_AilDj4RkgyTgeCnB_HfmGv-lmsOQ" /> <script>if (!window.customElements) { document.write(' <script type="text/javascript" src="/modules/custom/ckeditor_y3ti_plugins/bower_components/webcomponentsjs/custom-elements-es5-adapter.js"></script>  <script src="/modules/custom/ckeditor_y3ti_plugins/bower_components/webcomponentsjs/webcomponents-loader.js?snbnwj"></script> <script src="/modules/custom/ucsf_adobe_analytics/js/ucsf-data-layer.js?snbnwj" defer></script> <script src="/modules/custom/ucsf_adobe_analytics/js/ucsf-mag-marketing-data-layer.js?snbnwj" defer></script> <script src="https://assets.adobedtm.com/db5f13cb240b/b1130ce1ceae/launch-db8f55f3e131.min.js" defer></script> </head> <body class="alias-news-2023-12-426901-dementia-prevention-sleep-quality-midlife-matters-more path-node page-node-type-article loading"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-TSHCJ6" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="page"> <header class="combined-header-region "> <section class="universal-header-region"> <div class="universal-header"> <p id="site-name" class="universal-header__title">University of California San Francisco</p> <a href="https://giving.ucsf.edu" class="universal-header__give">Give to UCSF</a> </div> </section> <section class="header-region"> <div class="header "> <figure class="header--logo logo"> <a class="logo__link" href="/" title="Home" rel="home"> <picture class="logo__image"> <img fetchpriority="high" class="logo__img" src="/themes/custom/ucsf/logo.svg" alt="Home" height="41" width="83"> </picture> </a> </figure> <div class="header--search menu-item"><a href="/search" role="button" class="nolink mobile-search-reveal "><span>Search</span></a> <div class="home-search__form "> <form action="/search" accept-charset="utf-8" method="get" class="search__form"> <label for="header-search" class="visually-hidden">Small screen search</label> <input type="text" name="search" id="header-search" size="32" class="home-search__form-input " value="" placeholder="Search people, places, ideas" /> <input type="submit" id="edit-submit-header" name="op" value="Search" class="home-search__form-submit "> <fieldset class="fieldset-reset"> <legend class="visually-hidden">Choose what type of search to perform</legend> <div class="search-filter"> <label for="allucsf"> <input id="allucsf" type="radio" name="filter" class="visually-hidden search-filter__radio" value="All" checked> <div class="search-filter__label"> <span class="search-filter__option"></span> <span>All UCSF</span> </div> </label> <label for="newscenter"> <input id="newscenter" type="radio" name="filter" class="visually-hidden search-filter__radio" value="News"> <div class="search-filter__label"> <span class="search-filter__option"></span> <span>UCSF News Center</span> </div> </label> </div> </fieldset> </form> </div> </div> <div class="slicknav-placeholder"></div> <nav aria-label="Main" id="block-ucsf-main-menu" class="block block-menu navigation menu--main main-menu--mobile main-nav"> <ul block="block-ucsf-main-menu" class="menu-parent-wrapper"> <li class="menu-item menu-item--expanded menu-top-level__item" > <a href="https://www.ucsf.edu/about" class="nolink" data-drupal-link-system-path="node/130301">About</a> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about" title="UCSF Overview" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130301">Overview</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/mission-and-values" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/406481">Mission & Values</a> </li> <li class="menu-item menu-item--expanded dropdown-menu__item" > <span class="main-navigation__link dropdown-menu__link">Our Impact</span> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/achievements" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/413636">Achievements</a> </li> <li class="menu-item dropdown-menu__item" > <a href="/about/community-benefits" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="taxonomy/term/629">UCSF in the Community</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/history-1" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/93484">History</a> </li> <li class="menu-item menu-item--expanded dropdown-menu__item" > <span class="main-navigation__link dropdown-menu__link">Facts & Figures</span> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/ucsf-budget" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/403036">Budget</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/innovation" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/413691">Inventions & Entrepreneurship</a> </li> <li class="menu-item dropdown-menu__item" > <a href="/sites/default/files/2024-03/UCSF-General-Fact-Sheet-March-2024.pdf" class="main-navigation__link dropdown-menu__link">UCSF Fact Sheet</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded dropdown-menu__item" > <span class="main-navigation__link dropdown-menu__link">Administration</span> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://chancellor.ucsf.edu/leadership/chancellors-cabinet" target="_blank">Campus Leaders</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://chancellor.ucsf.edu/chancellor" class="main-navigation__link dropdown-menu__link">Chancellor</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://evcprovost.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Executive Vice Chancellor & Provost</a> </li> <li class="menu-item dropdown-menu__item" > <a href="/cgr" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/93347">Community & Government Relations</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://diversity.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Diversity & Outreach</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://fas.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Finance & Administrative Services</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://legal.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Legal Affairs</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/office-of-communications" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/423371">Office of Communications</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://giving.ucsf.edu/" class="main-navigation__link dropdown-menu__link">University Development & Alumni Relations</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/about/locations" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/96416">Locations</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded menu-top-level__item" > <a href="https://www.ucsf.edu/patient-care" class="nolink" data-drupal-link-system-path="node/130356">Patient Care</a> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/patient-care" title="Patient Care Overview" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130356">Overview</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsfhealth.org/" class="main-navigation__link dropdown-menu__link">UCSF Health</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsfbenioffchildrens.org/" class="main-navigation__link dropdown-menu__link">UCSF Benioff Children’s Hospitals</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsfdentalcenter.org/" class="main-navigation__link dropdown-menu__link">UCSF Dental Center</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://psych.ucsf.edu/lpphc" class="main-navigation__link dropdown-menu__link">Langley Porter Psychiatric Hospital and Clinics</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsfhealth.org/clinics" class="main-navigation__link dropdown-menu__link">Specialty Clinics</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/patient-care/clinical-trials" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/93456">Clinical Trials</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded menu-top-level__item" > <a href="https://www.ucsf.edu/research" class="nolink" data-drupal-link-system-path="node/130351">Research</a> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/research" title="Research Overview" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130351">Overview</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/research/partnerships" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130491">Partnerships</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://research.ucsf.edu" class="main-navigation__link dropdown-menu__link">Office of Research</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://innovation.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Innovation Ventures</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://postdocs.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Postdoctoral Scholars</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded menu-top-level__item" > <a href="https://www.ucsf.edu/education" class="nolink" data-drupal-link-system-path="node/130311">Education</a> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/education" title="Education Overview" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130311">Overview</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/education/admissions" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/409171">Admissions</a> </li> <li class="menu-item menu-item--expanded dropdown-menu__item" > <span class="main-navigation__link dropdown-menu__link">Schools & Programs</span> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="http://dentistry.ucsf.edu/" title="School of Dentistry" class="main-navigation__link dropdown-menu__link">School of Dentistry</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://medschool.ucsf.edu" title="School of Medicine" class="main-navigation__link dropdown-menu__link">School of Medicine</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://pharmacy.ucsf.edu" title="School Pharmacy" class="main-navigation__link dropdown-menu__link">School of Pharmacy</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://nursing.ucsf.edu" title="School of Nursing" class="main-navigation__link dropdown-menu__link">School of Nursing</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://graduate.ucsf.edu" title="Graduate Education" class="main-navigation__link dropdown-menu__link">Graduate Division</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://globalhealthsciences.ucsf.edu" title="Global Health Sciences" class="main-navigation__link dropdown-menu__link">Global Health Sciences</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded dropdown-menu__item" > <span class="main-navigation__link dropdown-menu__link">Resources for Students</span> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://registrar.ucsf.edu/academic-calendar" class="main-navigation__link dropdown-menu__link">Academic Calendar</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://career.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Career Center</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://finaid.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Financial Aid</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://catalog.ucsf.edu/" class="main-navigation__link dropdown-menu__link">General Catalog</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.library.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Library</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://registrar.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Registrar</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://success.ucsf.edu/" class="main-navigation__link dropdown-menu__link">Student Success Guide</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item menu-item--expanded menu-top-level__item" > <a href="https://www.ucsf.edu/news" class="nolink" data-drupal-link-system-path="node/413561">News & Media</a> <ul class="menu-child-wrapper"> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/news" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/413561">UCSF News Center</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://magazine.ucsf.edu/magazine" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/418411">UCSF Magazine</a> </li> <li class="menu-item dropdown-menu__item" > <a href="/campus-news" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="taxonomy/term/1006">Campus News</a> </li> <li class="menu-item dropdown-menu__item" > <a href="/news/media-coverage" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="taxonomy/term/413496">Media Coverage</a> </li> <li class="menu-item dropdown-menu__item" > <a href="https://www.ucsf.edu/news-media/journalists" class="main-navigation__link dropdown-menu__link" data-drupal-link-system-path="node/130226">Resources for Journalists</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </li> <li class="menu-item search menu-top-level__item" > <a href="/search" class="main-navigation__link" data-drupal-link-system-path="search">Search</a> </li> </ul> <div class="universal-header__give-mobile"> <a class="universal-header__give" href="https://giving.ucsf.edu">Give to UCSF</a> </div> </nav> <nav aria-label="Main" id="block-ucsf-main-menu-desktop" class="block block-menu navigation menu--main main-nav"> <ul block="block-ucsf-main-menu-desktop" class="main-nav__menu"> <li class="menu-item menu-item--expanded main-nav__submenu-wrapper" > <button class="main-nav__toggle menu-item-about-menu" aria-controls="aria-about-menu" aria-expanded=false > About </button> <div id="aria-about-menu" aria-labelledby="aria-label-about-menu" class="main-submenu main-submenu--0" data-level="level-0"> <button class="menu-item-close" aria-controls="aria-about-menu" aria-expanded=false> Close About menu. </button> <div data-section="section-about-menu" class="main-submenu__label main-submenu__label--0"> <span id="aria-label-about-menu" class="main-submenu__label-text">About</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/about" title="UCSF Overview" data-drupal-link-system-path="node/130301"> <span>Overview</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/mission-and-values" data-drupal-link-system-path="node/406481"> <span>Mission & Values</span> </a> </li> <li class="menu-item menu-item--expanded" > <button class="main-submenu__toggle menu-item-our-impact" aria-controls="aria-our-impact" aria-expanded=false > Our Impact </button> <span class="fas fa-angle-right"></span> <div id="aria-our-impact" aria-labelledby="aria-label-our-impact" class="main-submenu main-submenu--1" data-level="level-1"> <div data-section="section-our-impact" class="main-submenu__label"> <span id="aria-label-our-impact" class="main-submenu__label-text">Our Impact</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/about/achievements" data-drupal-link-system-path="node/413636"> <span>Achievements</span> </a> </li> <li class="menu-item" > <a href="/about/community-benefits" data-drupal-link-system-path="taxonomy/term/629"> <span>UCSF in the Community</span> </a> </li> </ul> </div> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/history-1" data-drupal-link-system-path="node/93484"> <span>History</span> </a> </li> <li class="menu-item menu-item--expanded" > <button class="main-submenu__toggle menu-item-facts--figures" aria-controls="aria-facts--figures" aria-expanded=false > Facts & Figures </button> <span class="fas fa-angle-right"></span> <div id="aria-facts--figures" aria-labelledby="aria-label-facts--figures" class="main-submenu main-submenu--1" data-level="level-1"> <div data-section="section-facts--figures" class="main-submenu__label"> <span id="aria-label-facts--figures" class="main-submenu__label-text">Facts & Figures</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/about/ucsf-budget" data-drupal-link-system-path="node/403036"> <span>Budget</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/innovation" data-drupal-link-system-path="node/413691"> <span>Inventions & Entrepreneurship</span> </a> </li> <li class="menu-item" > <a href="/sites/default/files/2024-03/UCSF-General-Fact-Sheet-March-2024.pdf"> <span>UCSF Fact Sheet</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded" > <button class="main-submenu__toggle menu-item-administration" aria-controls="aria-administration" aria-expanded=false > Administration </button> <span class="fas fa-angle-right"></span> <div id="aria-administration" aria-labelledby="aria-label-administration" class="main-submenu main-submenu--1" data-level="level-1"> <div data-section="section-administration" class="main-submenu__label"> <span id="aria-label-administration" class="main-submenu__label-text">Administration</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://chancellor.ucsf.edu/leadership/chancellors-cabinet"> <span>Campus Leaders</span> </a> </li> <li class="menu-item" > <a href="https://chancellor.ucsf.edu/chancellor"> <span>Chancellor</span> </a> </li> <li class="menu-item" > <a href="https://evcprovost.ucsf.edu/"> <span>Executive Vice Chancellor & Provost</span> </a> </li> <li class="menu-item" > <a href="/cgr" data-drupal-link-system-path="node/93347"> <span>Community & Government Relations</span> </a> </li> <li class="menu-item" > <a href="https://diversity.ucsf.edu/"> <span>Diversity & Outreach</span> </a> </li> <li class="menu-item" > <a href="https://fas.ucsf.edu/"> <span>Finance & Administrative Services</span> </a> </li> <li class="menu-item" > <a href="https://legal.ucsf.edu/"> <span>Legal Affairs</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/office-of-communications" data-drupal-link-system-path="node/423371"> <span>Office of Communications</span> </a> </li> <li class="menu-item" > <a href="https://giving.ucsf.edu/"> <span>University Development & Alumni Relations</span> </a> </li> </ul> </div> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/locations" data-drupal-link-system-path="node/96416"> <span>Locations</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded main-nav__submenu-wrapper" > <button class="main-nav__toggle menu-item-patient-care" aria-controls="aria-patient-care" aria-expanded=false > Patient Care </button> <div id="aria-patient-care" aria-labelledby="aria-label-patient-care" class="main-submenu main-submenu--0" data-level="level-0"> <button class="menu-item-close" aria-controls="aria-patient-care" aria-expanded=false> Close Patient Care menu. </button> <div data-section="section-patient-care" class="main-submenu__label main-submenu__label--0"> <span id="aria-label-patient-care" class="main-submenu__label-text">Patient Care</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/patient-care" title="Patient Care Overview" data-drupal-link-system-path="node/130356"> <span>Overview</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsfhealth.org/"> <span>UCSF Health</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsfbenioffchildrens.org/"> <span>UCSF Benioff Children’s Hospitals</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsfdentalcenter.org/"> <span>UCSF Dental Center</span> </a> </li> <li class="menu-item" > <a href="https://psych.ucsf.edu/lpphc"> <span>Langley Porter Psychiatric Hospital and Clinics</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsfhealth.org/clinics"> <span>Specialty Clinics</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/patient-care/clinical-trials" data-drupal-link-system-path="node/93456"> <span>Clinical Trials</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded main-nav__submenu-wrapper" > <button class="main-nav__toggle menu-item-research" aria-controls="aria-research" aria-expanded=false > Research </button> <div id="aria-research" aria-labelledby="aria-label-research" class="main-submenu main-submenu--0" data-level="level-0"> <button class="menu-item-close" aria-controls="aria-research" aria-expanded=false> Close Research menu. </button> <div data-section="section-research" class="main-submenu__label main-submenu__label--0"> <span id="aria-label-research" class="main-submenu__label-text">Research</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/research" title="Research Overview" data-drupal-link-system-path="node/130351"> <span>Overview</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/research/partnerships" data-drupal-link-system-path="node/130491"> <span>Partnerships</span> </a> </li> <li class="menu-item" > <a href="https://research.ucsf.edu"> <span>Office of Research</span> </a> </li> <li class="menu-item" > <a href="https://innovation.ucsf.edu/"> <span>Innovation Ventures</span> </a> </li> <li class="menu-item" > <a href="https://postdocs.ucsf.edu/"> <span>Postdoctoral Scholars</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded main-nav__submenu-wrapper" > <button class="main-nav__toggle menu-item-education" aria-controls="aria-education" aria-expanded=false > Education </button> <div id="aria-education" aria-labelledby="aria-label-education" class="main-submenu main-submenu--0" data-level="level-0"> <button class="menu-item-close" aria-controls="aria-education" aria-expanded=false> Close Education menu. </button> <div data-section="section-education" class="main-submenu__label main-submenu__label--0"> <span id="aria-label-education" class="main-submenu__label-text">Education</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/education" title="Education Overview" data-drupal-link-system-path="node/130311"> <span>Overview</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/education/admissions" data-drupal-link-system-path="node/409171"> <span>Admissions</span> </a> </li> <li class="menu-item menu-item--expanded" > <button class="main-submenu__toggle menu-item-schools--programs" aria-controls="aria-schools--programs" aria-expanded=false > Schools & Programs </button> <span class="fas fa-angle-right"></span> <div id="aria-schools--programs" aria-labelledby="aria-label-schools--programs" class="main-submenu main-submenu--1" data-level="level-1"> <div data-section="section-schools--programs" class="main-submenu__label"> <span id="aria-label-schools--programs" class="main-submenu__label-text">Schools & Programs</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="http://dentistry.ucsf.edu/" title="School of Dentistry"> <span>School of Dentistry</span> </a> </li> <li class="menu-item" > <a href="https://medschool.ucsf.edu" title="School of Medicine"> <span>School of Medicine</span> </a> </li> <li class="menu-item" > <a href="https://pharmacy.ucsf.edu" title="School Pharmacy"> <span>School of Pharmacy</span> </a> </li> <li class="menu-item" > <a href="https://nursing.ucsf.edu" title="School of Nursing"> <span>School of Nursing</span> </a> </li> <li class="menu-item" > <a href="https://graduate.ucsf.edu" title="Graduate Education"> <span>Graduate Division</span> </a> </li> <li class="menu-item" > <a href="https://globalhealthsciences.ucsf.edu" title="Global Health Sciences"> <span>Global Health Sciences</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded" > <button class="main-submenu__toggle menu-item-resources-for-students" aria-controls="aria-resources-for-students" aria-expanded=false > Resources for Students </button> <span class="fas fa-angle-right"></span> <div id="aria-resources-for-students" aria-labelledby="aria-label-resources-for-students" class="main-submenu main-submenu--1" data-level="level-1"> <div data-section="section-resources-for-students" class="main-submenu__label"> <span id="aria-label-resources-for-students" class="main-submenu__label-text">Resources for Students</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://registrar.ucsf.edu/academic-calendar"> <span>Academic Calendar</span> </a> </li> <li class="menu-item" > <a href="https://career.ucsf.edu/"> <span>Career Center</span> </a> </li> <li class="menu-item" > <a href="https://finaid.ucsf.edu/"> <span>Financial Aid</span> </a> </li> <li class="menu-item" > <a href="https://catalog.ucsf.edu/"> <span>General Catalog</span> </a> </li> <li class="menu-item" > <a href="https://www.library.ucsf.edu/"> <span>Library</span> </a> </li> <li class="menu-item" > <a href="https://registrar.ucsf.edu/"> <span>Registrar</span> </a> </li> <li class="menu-item" > <a href="https://success.ucsf.edu/"> <span>Student Success Guide</span> </a> </li> </ul> </div> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded main-nav__submenu-wrapper" > <button class="main-nav__toggle menu-item-news--media" aria-controls="aria-news--media" aria-expanded=false > News & Media </button> <div id="aria-news--media" aria-labelledby="aria-label-news--media" class="main-submenu main-submenu--0" data-level="level-0"> <button class="menu-item-close" aria-controls="aria-news--media" aria-expanded=false> Close News & Media menu. </button> <div data-section="section-news--media" class="main-submenu__label main-submenu__label--0"> <span id="aria-label-news--media" class="main-submenu__label-text">News & Media</span> </div> <ul class="main-submenu__menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/news" data-drupal-link-system-path="node/413561"> <span>UCSF News Center</span> </a> </li> <li class="menu-item" > <a href="https://magazine.ucsf.edu/magazine" data-drupal-link-system-path="node/418411"> <span>UCSF Magazine</span> </a> </li> <li class="menu-item" > <a href="/campus-news" data-drupal-link-system-path="taxonomy/term/1006"> <span>Campus News</span> </a> </li> <li class="menu-item" > <a href="/news/media-coverage" data-drupal-link-system-path="taxonomy/term/413496"> <span>Media Coverage</span> </a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/news-media/journalists" data-drupal-link-system-path="node/130226"> <span>Resources for Journalists</span> </a> </li> </ul> </div> </li> <li class="menu-item search" > <button class="main-nav__toggle menu-item-search-menu" aria-controls="aria-search-menu" aria-expanded=false > Open or Close Search Form </button> <div id="aria-search-menu" class="main-submenu main-nav__search"> <div class="home-search__form"> <form action="/search" accept-charset="utf-8" method="get" class="search__form"> <label for="header-desktop-search" class="visually-hidden">search</label> <input type="text" name="search" id="header-desktop-search" size="32" class="home-search__form-input" value="" placeholder="Search people, places, ideas" /> <fieldset class="fieldset-reset"> <legend class="visually-hidden">Choose what type of search to perform</legend> <div class="search-filter"> <label> <input type="radio" name="filter" class="visually-hidden search-filter__radio" value="All" checked> <div class="search-filter__label"> <span class="search-filter__option"></span> <span>All UCSF</span> </div> </label> <label> <input type="radio" name="filter" class="visually-hidden search-filter__radio" value="News"> <div class="search-filter__label"> <span class="search-filter__option"></span> <span>UCSF News Center</span> </div> </label> </div> </fieldset> <input type="submit" id="edit-submit" name="op" value="Search" class="home-search__form-submit"> </form> </div> </div> </li> </ul> </nav> </div> </section> </header> <div class="help"> <div class="region-highlighted"> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> <div class="region-content"> <div id="block-ucsf-content" class="block block-system block-system-main-block"> <main class="main "> <a id="main-content" tabindex="-1"></a> <div data-history-node-id="426901" class="article-twocol-banner twocolleftlight"> <figure class="article-twocol-banner-image"> <figure> <picture class="field field-two-column-banner-image field--type-entity-reference field--label-hidden field__item"> <source srcset="/sites/default/files/styles/two_col_banner_full/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_full_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (min-width: 1280px)" type="image/jpeg" width="720" height="780"/> <source srcset="/sites/default/files/styles/two_col_banner_large/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_large_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (min-width: 1050px) and (max-width: 1280px)" type="image/jpeg" width="640" height="693"/> <source srcset="/sites/default/files/styles/two_col_banner_medium/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_large_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (min-width: 850px) and (max-width: 1049px)" type="image/jpeg" width="1050" height="1138"/> <source srcset="/sites/default/files/styles/two_col_banner_narrow/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_large_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (min-width: 769px) and (max-width: 849px)" type="image/jpeg" width="850" height="921"/> <source srcset="/sites/default/files/styles/two_col_banner_narrow/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_large_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (max-width: 768px)" type="image/jpeg" width="850" height="921"/> <source srcset="/sites/default/files/styles/two_col_banner_x_small/public/2023-12/actogram-two-column.jpg 1x, /sites/default/files/styles/two_col_banner_x_small_2x/public/2023-12/actogram-two-column.jpg 2x" media="all and (max-width: 599px)" type="image/jpeg" width="600" height="650"/> <img loading="eager" src="/sites/default/files/styles/two_col_banner_medium/public/2023-12/actogram-two-column.jpg" width="1050" height="1138" alt="A sleep actogam chart that measures movement during sleep." class="element-fade"/> </picture> </figure> </figure> <header class="article-header article-twocol-header"> <ul class="article-header__byline"> <li class="article-header__primary-area" data-primary-area="pa-research">Research</li> <li class="article-header__date"> <div class="field field-date-and-time field--type-datetime field--label-hidden field__item"><time datetime="2024-01-03T18:09:34Z" class="datetime"> January 3, 2024 </time> </div> </li> </ul> <h1><span class="field field--name-title field--type-string field--label-hidden">For Dementia Prevention, Sleep Quality in Midlife Matters More</span> </h1> <h2 class="field field-sub-title field--type-text field--label-hidden article-header__subheading">UCSF-led study shows that tossing and turning may signal cognitive decline years later.</h2> <p class="article-header__author"> By <a href="https://www.ucsf.edu/bio/suzanne-leigh">Suzanne Leigh</a> <span class="article-art-credit">Sleep actogram by Yue Leng, Kristine Yaffe, Kristen Knutson; Neurology; ©2024 American Academy of Neurology</span> </p> </header> </div> <div class="main-content article-feature-content narrow-page"> <ul class="article-meta-share"> <li><a rel="nofollow" href="https://www.facebook.com/share.php?u=https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" target="_blank" title="Share on Facebook"><span class="fab fa-facebook-square"></span> <span class="indent-text">Share on Facebook</span></a></li> <li><a rel="nofollow" href="https://www.twitter.com/share?text=For Dementia Prevention, Sleep Quality in Midlife Matters More&url=https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" target="_blank" title="Share on Twitter"><span class="fa-brands fa-square-x-twitter"></span> <span class="indent-text">Share on Twitter</span></a></li> <li><a rel="nofollow" href="https://www.reddit.com/submit?url=https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more&title=For Dementia Prevention, Sleep Quality in Midlife Matters More" target="_blank" title="Share on Reddit"><span class="fab fa-reddit-square"></span> <span class="indent-text">Share on Reddit</span></a></li> <li><a rel="nofollow" href="/cdn-cgi/l/email-protection#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" title="Email this article"><span class="fas fa-envelope-square"></span> <span class="indent-text">Email this article</span></a></li> <li><a rel="nofollow" onclick="window.print();return false;" href="https://www.ucsf.edu/news/2023/12/426901/dementia-prevention-sleep-quality-midlife-matters-more" title="Print this article"><span class="fas fa-print"></span> <span class="indent-text">Print this article</span></a></li> </ul> <div class="page_narrow"><p>A new study, led by UC San Francisco, reveals that quality of sleep, not quantity, may play a part in the development of dementia decades before symptoms start.</p> <p>Unlike previous research that has primarily focused on sleep disturbance and cognitive impairment in late life, the 526 participants at the start of this study had an average age of 40.</p> <p>And while most earlier studies have relied on subjective measures of sleep quality, the researchers used a wrist activity monitor to record bedtime “sleep fragmentation,” which took into account the amount of time participants were immobile and the amount of time they were moving.</p> <p>The study, publishes in the journal <a href="https://n.neurology.org/lookup/doi/10.1212/WNL.0000000000208056"><em>Neurology</em></a> on Jan. 3, 2024.</p> <p>After tracking the participants’ sleep habits and evaluating their cognitive performance years later, the researchers found no association between cognition and sleep duration, in analyzing both self-reports and data from the wrist activity monitors.</p> <p>In contrast, those with higher levels of fragmented sleep were found to be up to three times as likely to score below average in cognitive testing as those with lower levels of fragmented sleep, when adjusted for factors like education, depression, body mass index, diabetes and hypertension.</p> <p>“Since Alzheimer’s disease pathology begins to accumulate in the brain many years before symptoms onset, it’s possible that sleep disturbances identified in late life – close to the time when memory loss becomes apparent – is actually the consequence of this pathology that has been developing silently over the years,” said first author <a href="https://profiles.ucsf.edu/yue.leng">Yue Leng</a>, PhD, of the UCSF Department of Psychiatry and Behavioral Sciences, and the <a href="https://weill.ucsf.edu/">Weill Institute for Neurosciences</a>.</p> <p>“Given the long, symptom-free window of Alzheimer’s disease and the high prevalence of sleep problems, the understanding of midlife sleep disturbances has significant public health implications.”</p> <p>Currently 1 in 9 Americans aged 65 and older suffer from Alzheimer’s. However, recent studies show that up to 40% of cases may be prevented or delayed by making health changes, including practicing good sleep hygiene.</p> <h2>A toll on executive function</h2> <p>The participants were part of CARDIA (Coronary Artery Risk Development In young Adults), a National Institutes of Health study. Over half were female; 56% were white and the remainder were Black. Their sleep habits were assessed over a three day-period on two occasions, approximately one year apart, and cognitive testing took place about 11 years later.</p> <p>The researchers divided the participants’ sleep quality scores into three groups: those with higher, moderate and lower levels of sleep fragmentation. Participants in the higher group were 2.10 to 2.97 times more likely to score below average on four tests measuring executive function, as well as working memory, processing speed and global cognition, compared to those in the lower group.</p> <p>Surprisingly, a fifth test, quantifying verbal memory, did not show differences between these two groups.</p> <p>“This confirms previous studies of older adults suggesting a strong association between sleep disorders and executive function, which might be due to the influence of sleep on the prefrontal cortex area, the seat of executive function, rather than verbal memory,” Leng said.</p> <p>No difference was found in cognitive scores between those with moderate sleep fragmentation compared with lower sleep fragmentation. Cognitive performance and sleep fragmentation did not differ by race or sex. There was no association between cognition and sleep quality when it was measured subjectively.</p> <p>“This research contributes to a body of literature that underscores the need to evaluate modifiable risk factors associated with cognitive aging,” said senior author <a href="https://memory.ucsf.edu/people/kristine-yaffe-md">Kristine Yaffe</a>, MD, of the UCSF departments of Psychiatry and Behavioral Sciences, Neurology, and Epidemiology and Biostatistics.</p> <p>“Future research is needed to study the link between sleep disturbances and cognition at different stages of life and to identify whether there are critical life periods when sleep is more strongly associated with cognition,” added Yaffe, who is a member of the first team of experts to determine that 30% of dementia risk is preventable. “This might open up new opportunities for the prevention of Alzheimer’s in late life.”</p> <p class="small-text"><strong>Co-Authors: </strong>Kristen Knutson, PhD, of UCSF and Mercedes R. Carnethon, PhD, of Northwestern University.</p> <p class="small-text"><strong>Funding:</strong> The CARDIA study is supported by contracts HHSN268201800003I, HHSN268201800004I, HHSN268 201800005I, HHSN268201800006I and HHSN268201800007I from the National Heart, Lung, and Blood Institute (NHLBI). The CARDIA Cognitive Function ancillary study is supported by NHLBI grant R01 HL122658. The authors report no relevant disclosures.</p> </div> <div class="tags-menu-region"> <h3 class="tags-menu__title">Topics</h3> <ul class="tags-menu"> <li class="tags-menu__item"><a href="/topics/aging" hreflang="en">Aging</a></li> <li class="tags-menu__item"><a href="/topics/alzheimers-and-dementia" hreflang="en">Alzheimer’s and Dementia</a></li> <li class="tags-menu__item"><a href="/topics/neurosciences" hreflang="en">Neurosciences</a></li> <li class="tags-menu__item"><a href="/topics/sleep" hreflang="en">Sleep</a></li> </ul> </div> </div> </main> <aside class="recommended-articles "> <div class="recommended-articles__banner"> <h2 class="recommended-articles__title">Recommended Reading</h2> </div> <div class="views-element-container"><div class="element-swoosh view view-articles-by-term view-id-articles_by_term view-display-id-block_1 js-view-dom-id-d0bc0ff8b05778c2549f5dfda94b65df60973a987994310eb3a95c380ec7160c"> <div class="view-content"> <div class="views-row"> <article data-history-node-id="428876" class="news-card" data-primary-area="pa-research"> <a href="https://www.ucsf.edu/news/2024/11/428876/ai-tool-helps-neurosurgeons-find-sneaky-cancer-cells" class="news-card__link"> <figure> <picture class="field field-card-image field--type-entity-reference field--label-hidden field__item"> <source srcset="/sites/default/files/styles/news_card__image/public/2024-11/shawn-hervey-jumper-surgery.jpg 1x, /sites/default/files/styles/news_card__image/public/2024-11/shawn-hervey-jumper-surgery.jpg 2x" media="all and (max-width: 599px)" type="image/jpeg" width="600" height="338"/> <img loading="lazy" src="/sites/default/files/styles/news_card__image/public/2024-11/shawn-hervey-jumper-surgery.jpg" width="600" height="338" alt="Neuroseurgon Shawn Hervey-Jumper wears surgical scrubs and a mask, along with surgical loupes, while he performs neurosurgery." class="element-fade"/> </picture> </figure> <header class="news-card__copy"> <ul class="article-header__byline"> <li class="article-header__primary-area" data-primary-area="pa-research">Research</li> <li class="article-header__date"> <div class="field field-date-and-time field--type-datetime field--label-hidden field__item"><time datetime="2024-11-13T18:57:03Z" class="datetime"> Nov. 13, 2024 </time> </div> </li> </ul> <h2><span class="field field--name-title field--type-string field--label-hidden">This AI Tool Helps Neurosurgeons Find Sneaky Cancer Cells</span> </h2> </header> </a> </article> </div> <div class="views-row"> <article data-history-node-id="428766" class="news-card" data-primary-area="pa-research"> <a href="https://www.ucsf.edu/news/2024/10/428766/artificial-receptors-could-help-us-solve-puzzle-olfaction" class="news-card__link"> <figure> <picture class="news-card-background"> <img class="element-fade" src="/themes/custom/ucsf/images/card/transparent-news-card.png" alt="Placeholder image" height="216" width="384" loading="lazy"> </picture> </figure> <header class="news-card__copy"> <ul class="article-header__byline"> <li class="article-header__primary-area" data-primary-area="pa-research">Research</li> <li class="article-header__date"> <div class="field field-date-and-time field--type-datetime field--label-hidden field__item"><time datetime="2024-10-31T20:58:06Z" class="datetime"> Oct. 31, 2024 </time> </div> </li> </ul> <h2><span class="field field--name-title field--type-string field--label-hidden">Artificial Receptors Could Help Us Solve the Puzzle of Olfaction</span> </h2> </header> </a> </article> </div> <div class="views-row"> <article data-history-node-id="428701" class="news-card" data-primary-area="pa-research"> <a href="https://www.ucsf.edu/news/2024/10/428701/poor-sleep-midlife-linked-faster-brain-atrophy" class="news-card__link"> <figure> <picture class="field field-card-image field--type-entity-reference field--label-hidden field__item"> <source srcset="/sites/default/files/styles/news_card__image/public/2024-10/brain-mri.jpg 1x, /sites/default/files/styles/news_card__image/public/2024-10/brain-mri.jpg 2x" media="all and (max-width: 599px)" type="image/jpeg" width="600" height="338"/> <img loading="lazy" src="/sites/default/files/styles/news_card__image/public/2024-10/brain-mri.jpg" width="600" height="338" alt="An MRI scan of a brain." class="element-fade"/> </picture> </figure> <header class="news-card__copy"> <ul class="article-header__byline"> <li class="article-header__primary-area" data-primary-area="pa-research">Research</li> <li class="article-header__date"> <div class="field field-date-and-time field--type-datetime field--label-hidden field__item"><time datetime="2024-10-23T16:37:45Z" class="datetime"> Oct. 23, 2024 </time> </div> </li> </ul> <h2><span class="field field--name-title field--type-string field--label-hidden">Poor Sleep in Midlife Is Linked to Faster Brain Atrophy</span> </h2> </header> </a> </article> </div> </div> </div> </div> <div class="footer-ctas-wrapper"> <div class="field field-ankle-cta field--type-entity-reference field--label-hidden field__items"> <div class="field__item"> <div class="clearfix text-formatted field body field--type-text-with-summary field--label-hidden field__item"><h2>Stay in touch with the latest updates.</h2> <p><a class="icon-media" data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="cab6a11f-4158-4d04-88f1-d511d9455ca2" href="https://www.ucsf.edu/subscribe-ucsf-news" title="Subscribe to UCSF News">Subscribe to UCSF News</a></p> </div> </div> <div class="field__item"> <div class="clearfix text-formatted field body field--type-text-with-summary field--label-hidden field__item"><h2>Are you a member of the news media?</h2> <p><a class="icon-media" data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="389ec7dc-e40f-4077-9e9c-884ccbea0dec" href="https://www.ucsf.edu/news-media/journalists" title="Resources for Journalists">Visit the Media Center</a></p> </div> </div> </div> </div> </aside> </div> </div> <footer class="footer-region"> <div class="footer"> <div class="logo-follow"> <figure class="footer-logo"> <a class="footer-logo__link" href="/"> <div class="footer-logo__image"> <img class="footer-logo__img" src="/themes/custom/ucsf/images/footer-logo.svg" alt="UCSF Footer Logo" width="100" height="100"> </div> </a> </figure> <div class="follow"> <h2>Follow Us:</h2> <ul> <li class="follow-facebook"><a href="https://www.facebook.com/ucsf"><span class="fab fa-facebook-f"></span> <span class="indent-text">Facebook</span></a></li> <li class="follow-twitter"><a href="https://www.twitter.com/ucsf"><span class="fab fa-x-twitter"></span> <span class="indent-text">Twitter</span></a></li> <li class="follow-youtube"><a href="https://www.youtube.com/ucsf"><span class="fab fa-youtube"></span> <span class="indent-text">YouTube</span></a></li> <li class="follow-instagram"><a href="https://www.instagram.com/ucsf"><span class="fab fa-instagram"></span> <span class="indent-text">Instagram</span></a></li> </ul> </div> </div> <nav aria-label="Main" id="block-ucsf-footer" class="block block-menu navigation menu--footer"> <ul block="block-ucsf-footer" class="menu"> <li class="menu-item" > <a href="https://www.ucsf.edu/cgr/advocacy" data-drupal-link-system-path="node/408041">Become a UCSF Advocate</a> </li> <li class="menu-item" > <a href="https://ucsfhealth.samaritan.com">Volunteer at UCSF Medical Center</a> </li> <li class="menu-item" > <a href="https://together.ucsf.edu/">Start a Fundraiser</a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/subscribe-ucsf-news" data-drupal-link-system-path="node/403161">Subscribe to UCSF News</a> </li> </ul> </nav> <nav aria-label="Main" id="block-footer2resources" class="block block-menu navigation menu--footer2"> <ul block="block-footer2resources" class="menu"> <li class="menu-item" > <a href="https://websites.ucsf.edu/azlist">A to Z Website List</a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/accessibility-resources" data-drupal-link-system-path="node/421786">Accessibility Resources</a> </li> <li class="menu-item" > <a href="https://policies.ucsf.edu/">Administrative Policies</a> </li> <li class="menu-item" > <a href="https://identity.ucsf.edu/">Brand Guidelines</a> </li> <li class="menu-item" > <a href="https://campuslifeserviceshome.ucsf.edu/">Campus Life Services</a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/locations" data-drupal-link-system-path="node/96416">Campus Maps</a> </li> <li class="menu-item" > <a href="https://www.ucsf.edu/about/working-ucsf" data-drupal-link-system-path="node/409191">Careers at UCSF</a> </li> <li class="menu-item" > <a href="https://chancellor.ucsf.edu/">Chancellor</a> </li> <li class="menu-item" > <a href="https://diversity.ucsf.edu/">Diversity & Outreach</a> </li> <li class="menu-item" > <a href="https://police.ucsf.edu/emergency-preparedness">Emergency Preparedness</a> </li> <li class="menu-item" > <a href="https://hr.ucsf.edu">Human Resources</a> </li> <li class="menu-item" > <a href="https://www.library.ucsf.edu/">Library</a> </li> <li class="menu-item" > <a href="https://directory.ucsf.edu/">People Directory</a> </li> <li class="menu-item" > <a href="https://police.ucsf.edu/">Police</a> </li> <li class="menu-item" > <a href="https://campuslifeservices.ucsf.edu/transportation/services/shuttles/">Shuttle Schedule</a> </li> <li class="menu-item" > <a href="https://profiles.ucsf.edu">UCSF Profiles</a> </li> </ul> </nav> <div id="block-popwiseblock" class="block block-block-content block-block-content6efc2b33-6a3d-487d-8945-4c884ad0df82"> <div class="clearfix text-formatted field body field--type-text-with-summary field--label-hidden field__item"><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="text/javascript" data-cfasync="false"> (function(W,i,s,e,P,o,p){W['WisePopsObject']=P;W[P]=W[P]||function(){ (W[P].q=W[P].q||[]).push(arguments)},W[P].l=1*new Date();o=i.createElement(s), p=i.getElementsByTagName(s)[0];o.async=1;o.src=e;p.parentNode.insertBefore(o,p) })(window,document,'script','//loader.wisepops.com/get-loader.js?v=1&site=dQ5haeqNrm','wisepops'); </script></div> </div> </div> <div class="footer-bottom"> <p>© 2024 The Regents of The University of California</p> <ul class="text-align: right;"> <li><a href="/sitemap.xml" style="left: -9999px; position:absolute;" tabindex="-1" aria-hidden="true">Sitemap</a></li> <li><a href="/sitemap">Site Map</a></li> <li><a href="/terms-of-use">Terms of Use</a></li> <li><a href="/feedback">Report an issue with UCSF.edu website</a></li> </ul> </div> </footer> </div> </div> <script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({"drupalLanguage":"en","drupalCountry":"US","siteName":"UC San Francisco","entityCreated":"1703700574","entityLangcode":"en","entityStatus":"1","entityUid":"11011","entityUuid":"5d53b81a-49cb-4cba-966f-a4fdc8955230","entityVid":"737496","entityName":"kquintanilla","entityType":"node","entityBundle":"article","entityId":"426901","entityTitle":"For Dementia Prevention, Sleep Quality in Midlife Matters More","entityTaxonomy":{"areas":{"726":"Research"},"article_type":{"714":"Press Release"},"topics":{"756":"Aging","413861":"Alzheimer’s and Dementia","666":"Neurosciences","413546":"Sleep"}},"userUid":0});</script>  <link name="polymer_platform" href="/modules/custom/ckeditor_y3ti_plugins/elements/build.html" rel="import" /> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/426901","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJxlkFtywzAIRTekRh9dkAZLxKZBwiOQXXX1UWN30rQ_DHN4XC7xholMaujvRmHlNlNRv-MUJa9SsJi6yKDa_QSKP3lGVZhx1KSiL1IzMH2hS2DA0LH6CRfYSKo6lUjAIQ8hCEzlpv4_utiCGZ0aGKlRVJ9qW4EvT-K0q2E-7mhRrx55zBQLV0h_iGxYGdaQ0DAaSXkt6y6iy8Fmlgn4yL9DgDrUGIPJOlTDcFjHjrAgJCrzr8bTBUUpeuJCQ1iBFaHGQyBAkgkDFOD-MPaEbiPc1T_iBT7g8wVkSY3RdWnWxoIZmLH28943tT4eN98BG5qw5A","theme":"ucsf","theme_token":null},"ajaxTrustedUrl":[],"dataLayer":{"defaultLang":"en","languages":{"en":{"id":"en","name":"English","direction":"ltr","weight":0}}},"statistics":{"data":{"nid":"426901"},"url":"\/core\/modules\/statistics\/statistics.php"},"views":{"ajax_path":"\/views\/ajax","ajaxViews":{"views_dom_id:d0bc0ff8b05778c2549f5dfda94b65df60973a987994310eb3a95c380ec7160c":{"view_name":"articles_by_term","view_display_id":"block_1","view_args":"756+413861+666+413546\/426901","view_path":"\/node\/426901","view_base_path":null,"view_dom_id":"d0bc0ff8b05778c2549f5dfda94b65df60973a987994310eb3a95c380ec7160c","pager_element":0}}},"user":{"uid":0,"permissionsHash":"0c730a228c7c7fb09ef69cc49872503ed212ec963125de64d7bd9d3929d14bf0"}}</script> <script src="/sites/default/files/js/js_ChBLFJmLnJSY1j9tLrWbRTmJImKSKrgUmJ7S1dxzYdk.js?scope=footer&delta=0&language=en&theme=ucsf&include=eJxlkFFuxDAIRC_krj96IIvYbEIXm8jgpO7p691E2kb9QehpYAbiAxOZ1NA_jcLKbaaifscpSl6lYDF1CQwYOlY_4QIbSVWnEgk45DENgak81P9HN1swo9OuhtlPoOgig2q_9BlVYUZ1USr6IjUD0w-6FvXuZ5YJ2HVp1iYMMzBj7Sf-UOvDaHZqYKRGUX2qbQW-vYnbCHf1r3rLkhrjBcEXfB9eyCNtsXCHhFeiu4guB3uWAHWsZgwm67AII3nFaGFBSM88l2HZsDKsIaENDUn5s-f8GUUpeuJCQ6_AilDj4RkgyTgeCnB_HfmGv-lmsOQ"></script> <script src="https://kit.fontawesome.com/0047baebb3.js" crossorigin="anonymous"></script> <script src="/sites/default/files/js/js_DGHzI4C8s2m5srCR8I7slhej7nbVRHo8VPE5sxHlbEQ.js?scope=footer&delta=2&language=en&theme=ucsf&include=eJxlkFFuxDAIRC_krj96IIvYbEIXm8jgpO7p691E2kb9QehpYAbiAxOZ1NA_jcLKbaaifscpSl6lYDF1CQwYOlY_4QIbSVWnEgk45DENgak81P9HN1swo9OuhtlPoOgig2q_9BlVYUZ1USr6IjUD0w-6FvXuZ5YJ2HVp1iYMMzBj7Sf-UOvDaHZqYKRGUX2qbQW-vYnbCHf1r3rLkhrjBcEXfB9eyCNtsXCHhFeiu4guB3uWAHWsZgwm67AII3nFaGFBSM88l2HZsDKsIaENDUn5s-f8GUUpeuJCQ6_AilDj4RkgyTgeCnB_HfmGv-lmsOQ"></script> <script type="text/javascript"> /*<![CDATA[*/ (function() { var sz = document.createElement('script'); sz.type = 'text/javascript'; sz.async = true; sz.src = '//siteimproveanalytics.com/js/siteanalyze_8343.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(sz, s); })(); /*]]>*/ </script> </body> </html>

CINXE.COM

For Dementia Prevention, Sleep Quality in Midlife Matters More | UC San Francisco