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(PDF) Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers
<!DOCTYPE html> <html > <head> <meta charset="utf-8"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <meta content="width=device-width, initial-scale=1" name="viewport"> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs"> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="90wxncMg5hGVnGui75o0ruOPxdMcpfouPjx-H26E2JxTAsAvkZuKdx4JFhkB30dnQ8BLzvyt7qfZjN9RV8UV6g" /> <meta name="citation_title" content="Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers" /> <meta name="citation_publication_date" content="2012" /> <meta name="citation_journal_title" content="journal of Environmental Engineering and Ecological Science" /> <meta name="citation_author" content="Tanasorn Tunsaringkarn" /> <meta name="citation_author" content="Tassanee Prueksasit" /> <meta name="citation_author" content="Mingkwan Kitwattanavong" /> <meta name="citation_author" content="Wattasit Siriwong" /> <meta name="citation_author" content="Saowanee Sematong" /> <meta name="citation_author" content="Kalaya Zapuang" /> <meta name="citation_author" content="Anusorn Rungsiyothin" /> <meta name="citation_volume" content="1" /> <meta name="citation_issue" content="1" /> <meta name="citation_firstpage" content="1" /> <meta name="citation_issn" content="2050-1323" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:url" content="https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers" /> <meta name="twitter:title" content="Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers" /> <meta name="twitter:description" content="Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test" /> <meta name="twitter:image" content="https://0.academia-photos.com/13106180/4296350/4994739/s200_herbert.publications.jpg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers" /> <meta property="og:title" content="Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test" /> <meta property="article:author" content="https://independent.academia.edu/HerbertPublications" /> <meta name="description" content="Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test" /> <title>(PDF) Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers</title> <link rel="canonical" href="https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = 'b43f0aba9f037340a252c2534aaaefd344df803d'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1740597873000); window.Aedu.timeDifference = new Date().getTime() - 1740597873000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test on workers was performed and assessed. By the appropriate intervention of wearing mask and hand washing during work shift, we determined whether or not there is cancer risk to the exposure of benzene, formaldehyde and acetaldehyde using urinary biomarkers. Methods: A cross sectional study was conducted in 38 workers of 6 gasoline stations in Pathumwan District, Bangkok, Thailand. Inhalation and ambient air concentrations of benzene, formaldehyde and acetaldehyde were evaluated by GC/FID and HPLC/UV detectors. Urinary trans, trans-muconic acid (t,t-MA), formaldehyde and acetaldehyde concentrations detected in gasoline workers before and after appropriate intervention were analyzed by GC/FID. Results: The average inhalation exposure concentrations of benzene, formaldehyde and acetaldehyde were 195.56, 12.60 and 5.74 μg/m3, respectively. The level of benzene exposure was significantly higher than the ambient air level (independent t-test, p \u0026lt; 0.01). The average lifetime cancer risk of the workers exposed to benzene, formaldehyde and acetaldehyde was determined at the values of 2.15E-04, 1.27E-05 and 2.69E-06, respectively. Benzene and formaldehyde values were higher than an acceptable criteria defined as 1E-06. The amount of urinary t,t-MA, formaldehyde and acetaldehyde in the workers daily after 7-days appropriate intervention (wearing masks as personal protective equipment (PPE) and hand washing) was decreased. Formaldehyde and acetaldehyde, which were detected in urine, showed significantly lower than before intervention (pair t-test, p \u0026lt; 0.001). Conclusions: Results from our study confirmed that the gasoline workers have high chances of cancer risk from daily exposure to benzene and formaldehyde. The urinary\u0026#39;s t,t-MA, formaldehyde and acetaldehyde could be considerably used as biomarkers in gasoline station workers. An appropriate intervention, using PPE and hand washing, could reduce the cancer risk.","author":[{"@context":"https://schema.org","@type":"Person","name":"Herbert Publications","url":"https://independent.academia.edu/HerbertPublications"}],"contributor":[],"dateCreated":"2014-09-02","dateModified":"2014-09-02","headline":"Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers","image":"https://attachments.academia-assets.com/34609983/thumbnails/1.jpg","inLanguage":"en","keywords":["Environmental Studies"],"publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}],"thumbnailUrl":"https://attachments.academia-assets.com/34609983/thumbnails/1.jpg","url":"https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers"}</script><style type="text/css">@media(max-width: 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window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":8175058,"created_at":"2014-09-02T16:06:33.513-07:00","from_world_paper_id":null,"updated_at":"2021-01-16T12:51:18.192-08:00","_data":{"abstract":"Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test on workers was performed and assessed. By the appropriate intervention of wearing mask and hand washing during work shift, we determined whether or not there is cancer risk to the exposure of benzene, formaldehyde and acetaldehyde using urinary biomarkers.\n\nMethods: A cross sectional study was conducted in 38 workers of 6 gasoline stations in Pathumwan District, Bangkok, Thailand. Inhalation and ambient air concentrations of benzene, formaldehyde and acetaldehyde were evaluated by GC/FID and HPLC/UV detectors. Urinary trans, trans-muconic acid (t,t-MA), formaldehyde and acetaldehyde concentrations detected in gasoline workers before and after appropriate intervention were analyzed by GC/FID.\n\nResults: The average inhalation exposure concentrations of benzene, formaldehyde and acetaldehyde were 195.56, 12.60 and 5.74 μg/m3, respectively. The level of benzene exposure was significantly higher than the ambient air level (independent t-test, p \u003c 0.01). The average lifetime cancer risk of the workers exposed to benzene, formaldehyde and acetaldehyde was determined at the values of 2.15E-04, 1.27E-05 and 2.69E-06, respectively. Benzene and formaldehyde values were higher than an acceptable criteria defined as 1E-06. The amount of urinary t,t-MA, formaldehyde and acetaldehyde in the workers daily after 7-days appropriate intervention (wearing masks as personal protective equipment (PPE) and hand washing) was decreased. Formaldehyde and acetaldehyde, which were detected in urine, showed significantly lower than before intervention (pair t-test, p \u003c 0.001).\n\nConclusions: Results from our study confirmed that the gasoline workers have high chances of cancer risk from daily exposure to benzene and formaldehyde. The urinary's t,t-MA, formaldehyde and acetaldehyde could be considerably used as biomarkers in gasoline station workers. An appropriate intervention, using PPE and hand washing, could reduce the cancer risk."},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [13106180]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":34609983,"attachmentType":"pdf"}"><img alt="First page of “Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/34609983/mini_magick20190322-28209-1k6f2t.png?1553244709" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Cancer risk analysis of benzene, formaldehyde and acetaldehyde on gasoline station workers</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="13106180" href="https://independent.academia.edu/HerbertPublications"><img alt="Profile image of Herbert Publications" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/13106180/4296350/4994739/s65_herbert.publications.jpg" />Herbert Publications</a></div><div class="ds-work-card--detail"><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">6 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 8175058; 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if (!viewCountBody) { throw new Error('Failed to find work views element'); } viewCountBody.textContent = `${commaizedViewCount} views`; } catch (error) { // Remove the whole views element if there was some issue parsing. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); throw new Error(`Failed to parse view count: ${viewCount}`, error); } }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Background: Benzene, formaldehyde and acetaldehyde are carcinogenic substances to which gasoline station workers are most likely exposed via inhalation. To evaluate these compounds in the ambient air of gasoline stations, the inhalation exposure test on workers was performed and assessed. By the appropriate intervention of wearing mask and hand washing during work shift, we determined whether or not there is cancer risk to the exposure of benzene, formaldehyde and acetaldehyde using urinary biomarkers. Methods: A cross sectional study was conducted in 38 workers of 6 gasoline stations in Pathumwan District, Bangkok, Thailand. Inhalation and ambient air concentrations of benzene, formaldehyde and acetaldehyde were evaluated by GC/FID and HPLC/UV detectors. Urinary trans, trans-muconic acid (t,t-MA), formaldehyde and acetaldehyde concentrations detected in gasoline workers before and after appropriate intervention were analyzed by GC/FID. Results: The average inhalation exposure concentrations of benzene, formaldehyde and acetaldehyde were 195.56, 12.60 and 5.74 μg/m3, respectively. The level of benzene exposure was significantly higher than the ambient air level (independent t-test, p < 0.01). The average lifetime cancer risk of the workers exposed to benzene, formaldehyde and acetaldehyde was determined at the values of 2.15E-04, 1.27E-05 and 2.69E-06, respectively. Benzene and formaldehyde values were higher than an acceptable criteria defined as 1E-06. The amount of urinary t,t-MA, formaldehyde and acetaldehyde in the workers daily after 7-days appropriate intervention (wearing masks as personal protective equipment (PPE) and hand washing) was decreased. Formaldehyde and acetaldehyde, which were detected in urine, showed significantly lower than before intervention (pair t-test, p < 0.001). Conclusions: Results from our study confirmed that the gasoline workers have high chances of cancer risk from daily exposure to benzene and formaldehyde. The urinary's t,t-MA, formaldehyde and acetaldehyde could be considerably used as biomarkers in gasoline station workers. An appropriate intervention, using PPE and hand washing, could reduce the cancer risk.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":34609983,"attachmentType":"pdf","workUrl":"https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":34609983,"attachmentType":"pdf","workUrl":"https://www.academia.edu/8175058/Cancer_risk_analysis_of_benzene_formaldehyde_and_acetaldehyde_on_gasoline_station_workers"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div><div class="ds-signup-banner-trigger-container"><div class="ds-signup-banner-trigger ds-signup-banner-trigger-control"></div></div><div class="ds-signup-banner ds-signup-banner-control"><div id="ds-signup-banner-close-button"><button class="ds2-5-button ds2-5-button--secondary ds2-5-button--inverse"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">close</span></button></div><div class="ds-signup-banner-ctas" data-impression-entity-id="8175058" data-impression-entity-type="2" data-impression-source="signup-banner"><img src="//a.academia-assets.com/images/academia-logo-capital-white.svg" /><h4 class="ds2-5-heading-serif-sm">Sign up for access to the world's latest research</h4><button class="ds2-5-button ds2-5-button--inverse ds2-5-button--full-width js-swp-download-button" data-signup-modal="{"location":"signup-banner"}">Sign up for free<span class="material-symbols-outlined" style="font-size: 20px" translate="no">arrow_forward</span></button></div><div class="ds-signup-banner-divider"></div><div class="ds-signup-banner-reasons"><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Get notified about relevant papers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Save papers to use in your research</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Join the discussion with peers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Track your impact</span></div></div></div><script>(() => { // Set up signup banner show/hide behavior: // 1. 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It is also found in vehicle exhaust. The aim of this study was to assess the health risk of inhalation exposure to benzene among gasoline station workers. The ambient benzene concentration was measured by personal sampling from 150 gasoline station workers (137 fueling workers and 13 cashiers). Additional data of working characteristics were collected by interviews and on-site observations. All workers were non-smokers and passive smoking was limited. Risk assessment of inhalation exposure was determined using the United State Environmental Protection Agency (USEPA), and showed a high risk of adverse health effect (Hazard Quotients (HQ) &gt;1) in 51.33% of workers. The cancer risk was increased from 1.35 × 10-8 to 1.52 × 10-4, and 70.67% of the workers had a lifetime cancer risk (&gt;Inhalation Unit Risk (IUR): 2.2 × 10-6). A significantly higher risk was found in fueling workers compared to cashiers, and in workers...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Risk Assessment on Benzene Exposure among Gasoline Station Workers","attachmentId":87372407,"attachmentType":"pdf","work_url":"https://www.academia.edu/81268980/Risk_Assessment_on_Benzene_Exposure_among_Gasoline_Station_Workers","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/81268980/Risk_Assessment_on_Benzene_Exposure_among_Gasoline_Station_Workers"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="7620138" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/7620138/Measurements_of_benzene_and_formaldehyde_in_a_medium_sized_urban_environment_Indoor_outdoor_health_risk_implications_on_special_population_groups">Measurements of benzene and formaldehyde in a medium sized urban environment. Indoor/outdoor health risk implications on special population groups</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="13767517" href="https://auth.academia.edu/SpyrosKarakitsios">Spyros Karakitsios</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental Monitoring and Assessment, 2009</p><p class="ds-related-work--abstract ds2-5-body-sm">In the present study, the results of a measurement campaign aiming to assess cancer risk among two special groups of population: policemen and laboratory technicians exposed to the toxic substances, benzene and formaldehyde are presented. The exposure is compared to general population risk. The results show that policemen working outdoor (traffic regulation, patrol on foot or in vehicles, etc.) are exposed at a significantly higher benzene concentration (3–5 times) than the general population, while the exposure to carbonyls is in general lower. The laboratory technicians appear to be highly exposed to formaldehyde while no significant variation of benzene exposure in comparison to the general population is recorded. The assessment revealed that laboratory technicians and policemen run a 20% and 1% higher cancer risk respectively compared to the general population. Indoor working place air quality is more significant in assessing cancer risk in these two categories of professionals, due to the higher Inhalation Unit Risk (IUR) of formaldehyde compared to benzene. Since the origin of the danger to laboratory technicians is clear (use of chemicals necessary for the experiments), in policemen the presence of carbonyls in indoor air concentrations due to smoking or used materials constitute a danger equal to the exposure to traffic originated air pollutants.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Measurements of benzene and formaldehyde in a medium sized urban environment. Indoor/outdoor health risk implications on special population groups","attachmentId":48395359,"attachmentType":"pdf","work_url":"https://www.academia.edu/7620138/Measurements_of_benzene_and_formaldehyde_in_a_medium_sized_urban_environment_Indoor_outdoor_health_risk_implications_on_special_population_groups","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/7620138/Measurements_of_benzene_and_formaldehyde_in_a_medium_sized_urban_environment_Indoor_outdoor_health_risk_implications_on_special_population_groups"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="37224743" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/37224743/Biological_monitoring_of_petrochemical_industry_workers_exposed_to_benzene_toluene_xylenes_methyl_ethyl_ketone_and_phenol_in_Southern_Iran">Biological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in Southern Iran</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="81715667" href="https://independent.academia.edu/journaljohe">journal johe</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2014</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Volatile organic compounds (VOCs), including carcinogens and toxic compounds, are produced in petrochemical industries. We undertook this study in order to study workers’ respiratory exposure to different VOC concentrations and compare the results with the urinary levels of its metabolites and study the correlation between them in petrochemical industries. Materials and Methods: Exposure to benzene, toluene, xylene isomers, phenol, and methyl ethyl ketone (MEK) was evaluated in 104 male subjects using personal sampling pump and charcoal sorbent tube at the breathing zone and analyzed using gas chromatography–mass spectrometry (GC-MS). The urine samples were analyzed using high-performance liquid chromatography (HPLC-UV) and gas chromatography-flame ionization detector (GC-FID). Results: The mean concentration of urinary trans,trans-muconic acid (t,t-MA), was 1431 µg/g creatinine and hippuric acid, methyl hippuric acid, phenol, and MEK were, 0.394, 0.444, 0.098 g/g creatinine, and 0.15 mg/l. The mean concentration of benzene in the breathing zone was greater than the threshold limit value (TLV) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). Conclusions: In this study, a more significant relationship was found between benzene in breathing zone and urinary t,t-MA in those exposed to benzene in concentrations higher than 1 ppm (r2 = 0.89) than lower than 1 ppm. Moreover, the same results were observed for other hydrocarbons and their level of urinary biological index. A more significant relationship was observed between phenol in breathing zone and urine through exposure to airborne phenol in concentrations of higher than 0.049 ppm than lower than 0.049 ppm (r2 = 0.75). The relationship between MEK in breathing zone and urinary MEK was more significant in concentrations of higher than 0.1 ppm (r2 = 0.79) than lower than 0.1 ppm.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Biological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in Southern Iran","attachmentId":57175906,"attachmentType":"pdf","work_url":"https://www.academia.edu/37224743/Biological_monitoring_of_petrochemical_industry_workers_exposed_to_benzene_toluene_xylenes_methyl_ethyl_ketone_and_phenol_in_Southern_Iran","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/37224743/Biological_monitoring_of_petrochemical_industry_workers_exposed_to_benzene_toluene_xylenes_methyl_ethyl_ketone_and_phenol_in_Southern_Iran"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="77138290" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/77138290/Factors_Affecting_Adverse_Health_Effects_of_Gasoline_Station_Workers">Factors Affecting Adverse Health Effects of Gasoline Station Workers</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39102084" href="https://aut.academia.edu/SariAndajani">Sari Andajani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Environmental Research and Public Health, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">This cross-sectional study examined the risk factors affecting adverse health effects from benzene exposure among gasoline station workers in Khon Kean province, Thailand. An interview questionnaire of adverse symptoms relating to benzene toxicity was administered to 151 workers. Area samplings for benzene concentration and spot urine for tt-muconic acid (tt-MA), a biomarker of benzene exposure, were collected. The factors associated with adverse symptoms were analysed by using multiple logistic regression. It was found that these symptoms mostly affected fuelling workers (77.5%), and the detected air benzene reached an action level or higher than 50% of NIOSH REL (&gt;50 ppb). The top five adverse symptoms, i.e., fatigue, headache, dizziness, nasal congestion, and runny nose, were reported among workers exposed to benzene. More specific symptoms of benzene toxicity were chest pain, bleeding/epistaxis, and anaemia. The detected tt-MA of workers was 506.7 ug/g Cr (IQR), which was a v...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Factors Affecting Adverse Health Effects of Gasoline Station Workers","attachmentId":84591055,"attachmentType":"pdf","work_url":"https://www.academia.edu/77138290/Factors_Affecting_Adverse_Health_Effects_of_Gasoline_Station_Workers","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/77138290/Factors_Affecting_Adverse_Health_Effects_of_Gasoline_Station_Workers"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="9296516" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/9296516/Characterization_and_Health_Risk_Assessment_of_Volatile_Organic_Compounds_in_Gas_Service_Station_Workers">Characterization and Health Risk Assessment of Volatile Organic Compounds in Gas Service Station Workers</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="21420507" href="https://thammasat.academia.edu/PensriWatchalayann">Pensri Watchalayann</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Gas service station workers who work near volatile organic compounds (VOCs) sources, such as gasoline vapor emissions, and motor vehicle exhausts, may be exposed to highly elevated VOCs levels. This study investigates air samples from gas service stations in Thailand to evaluate the health risks following inhalation exposure. Personal air samplings were obtained at nine gas service stations in Chonburi, Thailand from October to December 2007. The concentrations of benzene, toluene, ethylbenzene, xylenes, and hexane in the air from the workplaces were significantly higher than in a control group of office workers (p<0.05). However, all VOCs in these air samples were lower than TWA limit of Thailand and the OSHA standard. Samples of urine, collected after 8-h work periods which were analyzed for VOCs metabolites, including t,t muconic acid, hippuric acid, mandelic acid and m-hippuric acid, demonstrate that the average levels of metabolites in gas service station workers and in controls were close, except for t,t muconic acid of gas service station workers which displayed higher levels than the in the controls. The lifetime cancer and noncancer risks for the workers exposed to VOCs were also assessed. Results show that all nine gas service stations in this study had a elevated lifetime cancer risk ranging from 53 to 630 per million, thus exceeding the "normal" risk of 1 per million. For noncancer risks, the levels in all gas stations ranged between 0.03 and 0.4, which is well below the reference hazard level of 1.0. Benzene may the most important cause of both cancer and noncancer risk followed by 1,3 butadiene.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Characterization and Health Risk Assessment of Volatile Organic Compounds in Gas Service Station Workers","attachmentId":35557987,"attachmentType":"pdf","work_url":"https://www.academia.edu/9296516/Characterization_and_Health_Risk_Assessment_of_Volatile_Organic_Compounds_in_Gas_Service_Station_Workers","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/9296516/Characterization_and_Health_Risk_Assessment_of_Volatile_Organic_Compounds_in_Gas_Service_Station_Workers"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="83597747" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/83597747/Biomonitoring_of_gasoline_station_attendants_exposed_to_benzene_Effect_of_gender">Biomonitoring of gasoline station attendants exposed to benzene: Effect of gender</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32616996" href="https://independent.academia.edu/AneliseBarth">Anelise Barth</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Women are employed in increasing numbers as gasoline station attendants, a work category with risk of exposure to benzene. We have assessed the effect of gender on biomarkers of occupational benzene exposure. Gasoline station attendants (20 men and 20 women) and 40 control individuals (20 men and 20 women) with no history of occupational benzene exposure were evaluated. Benzene exposure was monitoring by environmental and biological measurements. Urinary trans,trans-muconic acid levels, well-known genetic and hematological alterations linked to benzene exposure, and non-cancer effects on the immune, hepatic, and renal systems were investigated. Our results suggest a potential effect of gender on some effects of occupational benzene exposure, particularly the hematological parameters and trans,trans-muconic acid levels. Despite limitations of our study, our findings provide important considerations about occupational exposure of women to benzene and may contribute to the development of occupational protection standards.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Biomonitoring of gasoline station attendants exposed to benzene: Effect of gender","attachmentId":88889876,"attachmentType":"pdf","work_url":"https://www.academia.edu/83597747/Biomonitoring_of_gasoline_station_attendants_exposed_to_benzene_Effect_of_gender","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/83597747/Biomonitoring_of_gasoline_station_attendants_exposed_to_benzene_Effect_of_gender"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="75467694" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/75467694/Determination_and_Risk_Assessment_of_Formaldehyde_and_Acetaldehyde_in_the_Ambient_Air_of_Gas_Stations_in_Salvador_Bahia_Brazil">Determination and Risk Assessment of Formaldehyde and Acetaldehyde in the Ambient Air of Gas Stations in Salvador, Bahia, Brazil</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="104431817" href="https://independent.academia.edu/V%C3%A2niaPalmeiraCampos">Vânia Palmeira Campos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of the Brazilian Chemical Society</p><p class="ds-related-work--abstract ds2-5-body-sm">Formaldehyde (FA) and acetaldehyde (AA) were determined in the ambient air of five gas stations (GS) in the city of Salvador, Bahia State, Brazil, using three passive samplers exposed simultaneously for 8 h and analysis by high-performance liquid chromatography-ultraviolet detection (HPLC-UV). The concentration ranges found were 3.31-5.78 μg m −3 for FA and 10.5-28.2 μg m −3 for AA. These values were below the exposure limits recommended by national and international agencies for occupational environments, however, FA concentrations were above the more restrictive limit (3.30 μg m −3) stablished by Texas Commission on Environmental Quality (TCEQ) for long-term outdoor exposure. The lifetime cancer risks (LCR) found associated with the exposure of GS employees to these aldehydes over the 30-year period varied between 4.51 × 10 −6-8.00 × 10 −6 for FA and 2.46 × 10 −6-6.60 × 10 −6 for AA. These values are above the acceptable limit set by the USEPA (1.0 × 10 −6), reinforcing the need for actions to minimize the occupational exposure, mainly to FA, which is associated with nasopharyngeal cancer.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Determination and Risk Assessment of Formaldehyde and Acetaldehyde in the Ambient Air of Gas Stations in Salvador, Bahia, Brazil","attachmentId":83224991,"attachmentType":"pdf","work_url":"https://www.academia.edu/75467694/Determination_and_Risk_Assessment_of_Formaldehyde_and_Acetaldehyde_in_the_Ambient_Air_of_Gas_Stations_in_Salvador_Bahia_Brazil","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/75467694/Determination_and_Risk_Assessment_of_Formaldehyde_and_Acetaldehyde_in_the_Ambient_Air_of_Gas_Stations_in_Salvador_Bahia_Brazil"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="80732198" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/80732198/Formaldehyde_and_cancer_risk_a_quantitative_review_of_cohort_studies_through_2006">Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37958418" href="https://independent.academia.edu/RobertTarone">Robert Tarone</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Oncology, 2007</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Occupational exposure to formaldehyde has been associated with excess risk of nasopharyngeal and selected other cancers. Patients and methods: We reviewed and pooled the results of cohort studies published through February 2007. Results: There were 5651 deaths from all cancers observed in six cohorts of industry workers and six of professionals, with a pooled relative risk (RR) of 0.95 for industry workers and of 0.87 for professionals. Nine deaths from nasopharyngeal cancer in three cohorts of industry workers yielded a pooled RR of 1.33, which declined to 0.49 after excluding six cases from one US plant. The pooled RR for lung cancer was 1.06 in industry workers and 0.63 in professionals. Corresponding values were 1.09 and 0.96 for oral and pharyngeal, 0.92 and 1.56 for brain, 0.85 and 1.31 for all lymphatic and hematopoietic cancers, and 0.90 and 1.39 for leukemia. Conclusions: Comprehensive review of cancer in industry workers and professionals exposed to formaldehyde shows no appreciable excess risk for oral and pharyngeal, sinonasal or lung cancers. A non-significantly increased RR for nasopharyngeal cancer among industry workers is attributable to a cluster of deaths in a single plant. For brain cancer and lymphohematopoietic neoplasms there were modestly elevated risks in professionals, but not industry workers.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006","attachmentId":87016947,"attachmentType":"pdf","work_url":"https://www.academia.edu/80732198/Formaldehyde_and_cancer_risk_a_quantitative_review_of_cohort_studies_through_2006","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/80732198/Formaldehyde_and_cancer_risk_a_quantitative_review_of_cohort_studies_through_2006"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="115027843" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115027843/Assessment_of_exposure_of_gas_station_attendants_in_Sri_Lanka_to_benzene_toluene_and_xylenes">Assessment of exposure of gas station attendants in Sri Lanka to benzene, toluene and xylenes</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32035571" href="https://radboudumc.academia.edu/PaulScheepers">Paul Scheepers</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental Research, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">Exposure to benzene, toluene and p-, m-, o-xylene (BTX) was studied in 29 gas station attendants and 16 office workers in Sri Lanka. The aim of this study was to assess the exposure level and identify potential exposure mitigating measures. Pre-and post-shift samples of end-exhaled air were collected and analysed for BTX on a thermal desorption gas chromatography mass spectrometry system (TD-GC-MS). Urine was collected at the same timepoints and analysed for a metabolite of benzene, S-phenyl mercapturic acid (SPMA), using liquid chromatography-mass spectrometry (LC-MS). Environmental exposure was measured by personal air sampling and analysed by gas chromatography flame ionization detection (GC-FID). Median (range) breathing zone air concentrations were 609 (65.1-1960) μg/m 3 for benzene and 746 (< 5.0-2770) μg/m 3 for toluene. Taking into account long working hours, 28% of the measured exposures exceeded the ACGIH threshold limit value (TLV) for an 8-h time-weighted average of 1.6 mg/m 3 for benzene. Xylene isomers were not detected. End-exhaled air concentrations were significantly increased for gas station attendants compared to office workers (p < 0.005). The difference was 1-3-fold in pre-shift and 2-5-fold in post-shift samples. The increase from pre-to post-shift amounted to 5-15-fold (p < 0.005). Pre-shift BTX concentrations in end-exhaled air were higher in smokers compared to non-smokers (p < 0.01). Exposure due to self-reported fuel spills was related to enhanced exhaled BTX (p < 0.05). The same was found for sleeping at the location of the gas station between two work-shifts. Benzene in end-exhaled air was moderately associated with benzene in the breathing zone (r = 0.422; p < 0.001). Median creatinine-corrected S-phenyl mercapturic acid (SPMA) was similar in pre-and post-shift (2.40 and 3.02 μg/g) in gas station attendants but increased in office workers (from 0.55 to 1.07 μg/g). In conclusion, working as a gas station attendant leads to inhalation exposure and occasional skin exposure to BTX. Smoking was identified as the most important co-exposure. Besides taking preventive measure to reduce exposure, the reduction of working hours to 40 h per week is expected to decrease benzene levels below the current TLV.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Assessment of exposure of gas station attendants in Sri Lanka to benzene, toluene and xylenes","attachmentId":111556272,"attachmentType":"pdf","work_url":"https://www.academia.edu/115027843/Assessment_of_exposure_of_gas_station_attendants_in_Sri_Lanka_to_benzene_toluene_and_xylenes","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/115027843/Assessment_of_exposure_of_gas_station_attendants_in_Sri_Lanka_to_benzene_toluene_and_xylenes"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="12475685" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/12475685/Early_hematological_and_immunological_alterations_in_gasoline_station_attendants_exposed_to_benzene">Early hematological and immunological alterations in gasoline station attendants exposed to benzene</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31315301" href="https://fiocruz.academia.edu/FFreitas">Fernando Freitas</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental Research, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">Introduction: Elucidation of effective biomarkers may provide tools for the early detection of biological alterations caused by benzene exposure and may contribute to the reduction of occupational diseases. This study aimed to assess early alterations on hematological and immunological systems of workers exposed to benzene. Methods: Sixty gasoline station attendants (GSA group) and 28 control subjects were evaluated. Environmental and biological monitoring of benzene exposure was performed in blood and urine. The potential effect biomarkers evaluated were δ-aminolevulinate dehydratase (ALA-D) activity, CD80 and CD86 expression in lymphocytes and monocytes, and serum interleukin-8 (IL-8). The influence of confounding factors and toluene co-exposure were considered. Results: Although exposures were below ACGIH (American Conference of Governmental Industrial Hygienists) limits, reduced ALA-D activity, decreased CD80 and CD86 expression in monocytes and increased IL-8 levels were found in the GSA group compared to the control subjects. Furthermore, according to multiple linear regression analysis, benzene exposure was associated to a decrease in CD80 and CD86 expression in monocytes. Conclusions: These findings suggest, for the first time, a potential effect of benzene exposure on ALA-D activity, CD80 and CD86 expression, IL-8 levels, which could be suggested as potential markers for the early detection of benzene-induced alterations.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Early hematological and immunological alterations in gasoline station attendants exposed to benzene","attachmentId":46155826,"attachmentType":"pdf","work_url":"https://www.academia.edu/12475685/Early_hematological_and_immunological_alterations_in_gasoline_station_attendants_exposed_to_benzene","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/12475685/Early_hematological_and_immunological_alterations_in_gasoline_station_attendants_exposed_to_benzene"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":34609983,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":34609983,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_34609983" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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benzene in gasoline filling-station attendants</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="6393255" href="https://independent.academia.edu/PaoloFaranda">Paolo Faranda</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Toxicology Letters, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparison of exposure assessment methods in occupational exposure to benzene in gasoline filling-station attendants","attachmentId":49570976,"attachmentType":"pdf","work_url":"https://www.academia.edu/4899669/Comparison_of_exposure_assessment_methods_in_occupational_exposure_to_benzene_in_gasoline_filling_station_attendants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span 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