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KEGG ENZYME: 1.1.3.39
<!doctype html> <html><head> <title>KEGG ENZYME: 1.1.3.39</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1732512473"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1732512473"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1732512473" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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} } } function Link_XtrctSeq2(form) { var dna_from; var dna_to; var dna_len; var plus_up = Number(form.XtrctSeq_UP.value) ; var plus_down = Number(form.XtrctSeq_DOWN.value); var vector = Number(form.VECTOR.value); var org = form.ORG.value; var chr = form.CHR.value; var kid = form.KEGGID.value; var url; if (plus_up == 0 && plus_down == 0) { url = "/entry/-f+-n+n+" + kid; } else { if (vector == 1) { dna_from = Number(form.FROM.value) - plus_up; dna_to = Number(form.TO.value) + plus_down; } else { dna_from = Number(form.FROM.value) - plus_down; dna_to = Number(form.TO.value) + plus_up; } url = "/dbget-bin/cut_sequence_genes.pl?FROM=" + dna_from + "&TO=" + dna_to +"&VECTOR=" + vector + "&ORG=" + org; if (chr) url += "&CHR=" + chr; } //window.open( url, "_self" ); location.href = url; } function go_taxonomy(form,params){ for(var key in params){ if(form[key]){ form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="683"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg2.gif"></a></td><td> </td><td><a name="enzyme:1.1.3.39"></a><font class="title2">ENZYME: 1.1.3.39</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_enzyme.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/kegg-bin/search_htext" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">EC 1.1.3.39 Enzyme <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">nucleoside oxidase (H2O2-forming)<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Class</span></th> <td class="td20 defd"><div class="cel">Oxidoreductases;<br> Acting on the CH-OH group of donors;<br> With oxygen as acceptor<br> <button class="btn" onclick="location.href='/brite/ko01000+1.1.3.39';return false;">BRITE hierarchy</button></div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Sysname</span></th> <td class="td21 defd"><div class="cel">nucleoside:oxygen 5'-oxidoreductase (H2O2-forming)<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Reaction(IUBMB)</span></th> <td class="td20 defd"><div class="cel">adenosine + 2 O2 + H2O = 9-riburonosyladenine + 2 H2O2 (overall reaction) [RN:<a href="/entry/R05695">R05695</a>];<br> (1a) adenosine + O2 = 5'-dehydroadenosine + H2O2 [RN:<a href="/entry/R05696">R05696</a>];<br> (1b) 5'-dehydroadenosine + O2 + H2O = 9-riburonosyladenine + H2O2 [RN:<a href="/entry/R05697">R05697</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction(KEGG)</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R05695">R05695</a> <a href="/entry/R05696">R05696</a> <a href="/entry/R05697">R05697</a><br> <button class="btn" onclick="location.href='/entry/R05695/R05696/R05697';return false;">Reaction</button></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Substrate</span></th> <td class="td20 defd"><div class="cel">adenosine [CPD:<a href="/entry/C00212">C00212</a>];<br> O2 [CPD:<a href="/entry/C00007">C00007</a>];<br> H2O [CPD:<a href="/entry/C00001">C00001</a>];<br> 5'-dehydroadenosine [CPD:<a href="/entry/C11500">C11500</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Product</span></th> <td class="td21 defd"><div class="cel"><div class="cel">9-riburonosyladenine [CPD:<a href="/entry/C11501">C11501</a>];<br> H2O2 [CPD:<a href="/entry/C00027">C00027</a>];<br> 5'-dehydroadenosine [CPD:<a href="/entry/C11500">C11500</a>]<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Comment</span></th> <td class="td20 defd"><div class="cel">A heme-containing flavoprotein (FAD). Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides and arabinosides) are substrates, but ribose and nucleotides are not substrates. The overall reaction takes place in two separate steps, with the 5'-dehydro nucleoside being released from the enzyme to serve as substrate for the second reaction. This enzyme differs from EC <a href="/entry/1.1.3.28">1.1.3.28</a>, nucleoside oxidase, as it produces hydrogen peroxide rather than water.<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">History</span></th> <td class="td21 defd"><div class="cel">EC 1.1.3.39 created 2001<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Reference</span></th> <td class="td20 defd"><div class="cel">1 [PMID:<a href="https://www.ncbi.nlm.nih.gov/pubmed/16535726">16535726</a>]</div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Authors</span></th> <td class="td21 repd"><div class="cel">Koga S, Ogawa J, Cheng L, Choi Y, Yamada H, Shimizu S.</div></td></tr> <tr><th class="th20 rept tal vtop"><span class="nowrap"> Title</span></th> <td class="td20 repd"><div class="cel">Nucleoside Oxidase, a Hydrogen Peroxide-Forming Oxidase, from Flavobacterium meningosepticum.</div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Journal</span></th> <td class="td21 repd"><div class="cel">Appl Environ Microbiol 63:4282-4286 (1997)<br>DOI:<a href="https://doi.org/10.1128/AEM.63.11.4282-4286.1997">10.1128/AEM.63.11.4282-4286.1997</a></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExplorEnz - The Enzyme Database: </span></td><td><a href="https://www.enzyme-database.org/query.php?ec=1.1.3.39">1.1.3.39</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">IUBMB Enzyme Nomenclature: </span></td><td><a href="https://iubmb.qmul.ac.uk/enzyme/EC1/1/3/39.html">1.1.3.39</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExPASy - ENZYME nomenclature database: </span></td><td><a href="https://enzyme.expasy.org/EC/1.1.3.39">1.1.3.39</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">BRENDA, the Enzyme Database: </span></td><td><a href="https://www.brenda-enzymes.info/enzyme.php?ecno=1.1.3.39">1.1.3.39</a></td></tr></table></td></tr> </table></td></tr></table> <br></td><td class="vtop"><div class="aw" style="margin-top:46px;"><div class="fm at th20"> All links </div> <div class="fm"><pre class="fm" style="margin-left:1em"> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+6+ec:1.1.3.39">Chemical substance (6)</a></span> <a href="/dbget-bin/get_linkdb?-t+compound+ec:1.1.3.39">KEGG COMPOUND (6)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+7+ec:1.1.3.39">Chemical reaction (6)</a></span> <a href="/dbget-bin/get_linkdb?-t+reaction+ec:1.1.3.39">KEGG REACTION (3)</a> <a href="/dbget-bin/get_linkdb?-t+rclass+ec:1.1.3.39">KEGG RCLASS (3)</a> <a href="/dbget-bin/get_linkdb?-t+alldb+ec:1.1.3.39">All databases (12)</a> <br><a href="/dbget-bin/get_linkdb?-N+ec:1.1.3.39">Download RDF</a> </pre> </div></div> </td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>