Search results for: mucormycosis

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There are a number of cases of this in the literature, most commonly in the head and neck region arising from sinuses. It is also usually found in immunocompromised patient subgroups. This study reviewed a number of cases of mucormycosis in previously fit and healthy young trauma patients to assess predisposing factors for infection and adequacy of current treatment paradigms. These trauma patients likely contracted the fungal infection from the soil at the site of the incident. Despite early washout and debridement of the wounds at the scene of the injury and on arrival in hospital, both these patients contracted mucormycosis. It was suspected that inadequate early debridement of soil contaminated limbs was one of the major factors that can lead to catastrophic tissue necrosis. In both cases, this resulted in the patients having a higher level of amputation than would have initially been required based on the level of their injury. This was secondary to cutaneous and soft tissue necrosis secondary to the fungal infiltration leading to osteomyelitis and systemic sepsis. In the literature, it appears diagnosis is often protracted in this condition secondary to inadequate early treatment and long processing times for fungal cultures. If fungal cultures were sent at the time of first assessment and adequate debridements are performed aggressively early, it could lead to these critically unwell trauma patients receiving appropriate antifungal and surgical treatment earlier in their episode of care. This is likely to improve long term outcomes for these patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mucormycosis" title="mucormycosis">mucormycosis</a>, <a href="https://publications.waset.org/abstracts/search?q=plastic%20surgery" title=" plastic surgery"> plastic surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=osteomyelitis" title=" osteomyelitis"> osteomyelitis</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma" title=" trauma"> trauma</a> </p> <a href="https://publications.waset.org/abstracts/138035/impact-of-mucormycosis-infection-in-limb-salvage-for-trauma-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138035.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">213</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Common Causes of Eye Removal Surgery in Turkish Patients: A Review of 226 Cases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Titap%20Yazicioglu">Titap Yazicioglu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: To determine the etiological factors responsible for the eye removal surgery and to evaluate our surgical results. Material and Methods: Medical records of 226 patients, who underwent eye removal surgery, were analyzed retrospectively. Demographic information, clinical history, surgical procedure, and histopathological data were all collected. Evisceration surgery was performed under general anesthesia in all patients except tumor cases and one patient with rhino-orbital mucormycosis. The patients were followed for an average of 16.46卤10.78 months and checked for the possible complications, cosmesis, and functional results.Results: 144 men, and 82 women,with a mean age of 41.78卤22.6 years, were underwent enucleation (n=15) or evisceration (n=211) due to traumatic (n=169) and non-traumatic (n=57) causes. In the traumatic group, 79.8% of 169 patients were injured by penetrating and 14.2% by blunt trauma.3.6% of the patients were injured in a traffic accident, and 2.4% of them were injured by explosives. In the non-traumatic group, 40% of 25 patients had post-traumatic endophthalmitis, 32% had endophthalmitis due to corneal ulceration and melting, and 24% had endophthalmitis after cataract surgery. One patient had panophthalmitis due to rhino-orbital mucormycosis. Another cause in the non-traumatic group was glaucoma, of which 92.3% had neovascular glaucoma, and 8.7% had congenital glaucoma. Of the 14 patients who were enucleated for tumor, 35.7% had retinoblastoma, 14.3% had medulloepithelioma, 42.9% had uveal melanoma, and 7.1% had metastatic tumor from paranasal sinuses.The most common complaint in the follow-up period was discharging, seen in all prosthesis-wearing patients. 13.3% of the patients had itching due to ocular prosthesis. 4.4% of the patients were complaining about deep superior sulcus. 4.4% had pyogenic granuloma, and 17.8% had implant exposure. Conclusion: Etiological factors should be carefully evaluated, and precautions should be taken in order to reduce the devastating effect of the physical loss of the eye. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enucleation" title="enucleation">enucleation</a>, <a href="https://publications.waset.org/abstracts/search?q=evisceration" title=" evisceration"> evisceration</a>, <a href="https://publications.waset.org/abstracts/search?q=ocular%20injury" title=" ocular injury"> ocular injury</a>, <a href="https://publications.waset.org/abstracts/search?q=etiology" title=" etiology"> etiology</a>, <a href="https://publications.waset.org/abstracts/search?q=frequency" title=" frequency"> frequency</a> </p> <a href="https://publications.waset.org/abstracts/152395/common-causes-of-eye-removal-surgery-in-turkish-patients-a-review-of-226-cases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152395.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> The First Fungal Identification from Mini-BAL of Critical COVID-19 Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Fallah">Fatemeh Fallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Ensieh%20Lotfali"> Ensieh Lotfali</a>, <a href="https://publications.waset.org/abstracts/search?q=Leila%20Azimi"> Leila Azimi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hannan%20Khodaei"> Hannan Khodaei</a>, <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Rajabnejad"> Maryam Rajabnejad</a>, <a href="https://publications.waset.org/abstracts/search?q=Nafiseh%20Abdollahi"> Nafiseh Abdollahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Tayebi"> Hossein Tayebi</a>, <a href="https://publications.waset.org/abstracts/search?q=Saham%20Ansari"> Saham Ansari</a>, <a href="https://publications.waset.org/abstracts/search?q=Saeedeh%20Yaghoubi"> Saeedeh Yaghoubi</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdollah%20Karimi"> Abdollah Karimi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Coronavirus disease 2019 (COVID-19) has become a worldwide issue due to its high prevalence and rapid transmission. Fungal infections have been detected in COVID-19 patients, leading to increased morbidity and mortality. Objectives: This study aimed to isolate Aspergillus fumigatus and Mucor spp. on mini-bronchoalveolar lavage samples obtained from children with COVID-19 hospitalized in an Iranian children鈥檚 hospital. Methods: A cross-sectional descriptive study was performed on mini-bronchoalveolar lavage samples from children confirmed positive for COVID-19 admitted to ICU with a ventilator from April 2021 to February 2022. Demographic characteristics were recorded, and fungal DNA was extracted from mini-BAL samples taken from children. Nested PCR was made with two primers for Aspergillus fumigatus and Mucor spp. Results: Out of 100 children with COVID-19, all samples were negative for Aspergillus fumigatus; however, 12 cases were positive for BAL PCR for Mucor spp. Among the 12 patients, fever, shortness of breath, cough, and decreased level of consciousness were reported in 8.3% (n: 1), 16.6% (n: 2), 25% (n: 3), and 25% (n: 3), respectively. Most cases (41.7%; n: 5) suffered from heart disease, followed by underlying malignancy (33.4%; n: 4). All positive BAL PCR for Mucor spp. cases had significantly higher chest CT scan scores and spent more time under a ventilator. Conclusions: The identification of COVID-19 with Mucor spp. was observed among 12% (n: 12) of children hospitalized in a COVID-19 ICU. When dealing with pediatric COVID-19 patients, clinicians should consider the differential diagnosis of fungal co-infections and have a low threshold to begin treatment. Moreover, it is highly advisable to take prophylactic measures, such as properly using corticosteroids and shortening the intubation time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aspergillosis" title="aspergillosis">aspergillosis</a>, <a href="https://publications.waset.org/abstracts/search?q=COVID-19%20identification" title=" COVID-19 identification"> COVID-19 identification</a>, <a href="https://publications.waset.org/abstracts/search?q=mucormycosis" title=" mucormycosis"> mucormycosis</a>, <a href="https://publications.waset.org/abstracts/search?q=paediatrics" title=" paediatrics"> paediatrics</a> </p> <a href="https://publications.waset.org/abstracts/184705/the-first-fungal-identification-from-mini-bal-of-critical-covid-19-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184705.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">27</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Invasive Sino-Orbital Fungal Infection in Immucocompetent Patient</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sabreen%20Sulaiman%20Alshmali">Sabreen Sulaiman Alshmali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Invasive sino-orbital fungal infections are rare but challenging conditions that can occur in immunocompetent individuals. These infections are often difficult to diagnose and can result in severe complications if not treated promptly. Mucormycosis and other fungal species can colonize the paranasal sinuses and, under certain conditions, progress to aggressive, locally invasive masses. Objective: This case report aims to highlight the occurrence of invasive sino-orbital fungal infections in an immunocompetent patient, emphasizing the diagnostic and management challenges associated with these infections. Case Report: A 57-year-old asthmatic man presented with left infraorbital pain and swelling lasting two months. Radiological investigations, including MRI and CT scans, revealed an extensive fungal mass involving the right maxillary sinus and orbital floor. An incisional biopsy confirmed the diagnosis of an aggressive fungal infection characterized by septate hyphae. Management: The patient underwent surgical debulking and functional endoscopic sinus surgery (FESS) followed by orbital floor reconstruction with a Patient specific PEEK ( Polyetherketone) implant to address the defect and prevent enophthalmos. Antifungal therapy with intravenous amphotericin B, followed by oral voriconazole was administered. Outcome: The patient responded well to the treatment, with resolution of symptoms and improved visual function. Regular follow-up is ongoing to monitor for potential recurrence. Conclusion: This case underscores the importance of considering fungal infections in the differential diagnosis of orbital floor pathologies, even in immunocompetent individuals. Early identification, a multidisciplinary approach with prompt treatment, including medical therapy and surgical intervention with possible reconstruction , are crucial for optimal outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=orbital%20floor" title="orbital floor">orbital floor</a>, <a href="https://publications.waset.org/abstracts/search?q=fungal%20infection" title=" fungal infection"> fungal infection</a>, <a href="https://publications.waset.org/abstracts/search?q=immunocompetent" title=" immunocompetent"> immunocompetent</a>, <a href="https://publications.waset.org/abstracts/search?q=aggressive%20fungal" title=" aggressive fungal"> aggressive fungal</a> </p> <a href="https://publications.waset.org/abstracts/198448/invasive-sino-orbital-fungal-infection-in-immucocompetent-patient" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/198448.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">4</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2025 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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Search results for: mucormycosis