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Please <a href="/wiki/Help:Link" title="Help:Link">introduce links</a> to this page from <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special%3ASearch&redirs=1&search=Silvia+Bolland&fulltext=Search&ns0=1&title=Special%3ASearch&advanced=1&fulltext=Silvia+Bolland">related articles</a></span>; try the <a rel="nofollow" class="external text" href="https://edwardbetts.com/find_link?q=Silvia_Bolland">Find link tool</a> for suggestions. <span class="date-container"><i>(<span class="date">January 2022</span>)</i></span></div></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox biography vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size:125%;"><div class="fn">Silvia Bolland</div></th></tr><tr><td colspan="2" class="infobox-image"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Silvia_Bolland.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/7/70/Silvia_Bolland.jpg" decoding="async" width="193" height="220" class="mw-file-element" data-file-width="193" data-file-height="220" /></a></span></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><b>Scientific career</b></td></tr><tr><th scope="row" class="infobox-label">Fields</th><td class="infobox-data category"><a href="/wiki/Biomedicine" title="Biomedicine">Biomedicine</a></td></tr><tr><th scope="row" class="infobox-label">Institutions</th><td class="infobox-data"><a href="/wiki/National_Institute_of_Allergy_and_Infectious_Diseases" title="National Institute of Allergy and Infectious Diseases">National Institute of Allergy and Infectious Diseases</a></td></tr><tr style="display:none"><td colspan="2"> </td></tr></tbody></table> <p><b>Silvia Bolland</b> is an American biomedical scientist serving as chief of the <a href="/wiki/Autoimmunity" title="Autoimmunity">autoimmunity</a> and <a href="/wiki/Functional_genomics" title="Functional genomics">functional genomics</a> section at the <a href="/wiki/National_Institute_of_Allergy_and_Infectious_Diseases" title="National Institute of Allergy and Infectious Diseases">National Institute of Allergy and Infectious Diseases</a>. </p><p>She earned a Ph.D. in molecular biology from the <a href="/wiki/University_of_Cantabria" title="University of Cantabria">University of Cantabria</a> and received postdoctoral training at <a href="/wiki/Harvard_University" title="Harvard University">Harvard</a> and <a href="/wiki/Rockefeller_University" title="Rockefeller University">Rockefeller University</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Her areas of research include the identification of new genetic modifiers of systemic <a href="/wiki/Autoimmune_disease" title="Autoimmune disease">autoimmune disease</a>, dose effect of <a href="/wiki/Toll-like_receptor" title="Toll-like receptor">Toll-like receptor</a> genes and its role in autoimmune <a href="/wiki/Pathologies" class="mw-redirect" title="Pathologies">pathologies</a>, and inhibitory signaling pathways mediated by the IgG <a href="/wiki/Fc_receptor" title="Fc receptor">Fc receptor</a> (<a href="/wiki/FCGR2B" title="FCGR2B">Fc gamma RIIB</a>) and the <a href="/wiki/Phosphoinositol" class="mw-redirect" title="Phosphoinositol">phosphoinositol</a> 5-phosphatase (SHIP).<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Selected_works">Selected works</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Silvia_Bolland&action=edit&section=1" title="Edit section: Selected works"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFOnoBollandTempstRavetch1996" class="citation journal cs1">Ono, Masao; Bolland, Silvia; Tempst, Paul; Ravetch, Jeffrey V. (September 1996). "Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB". <i>Nature</i>. <b>383</b> (6597): 263–266. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1996Natur.383..263O">1996Natur.383..263O</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F383263a0">10.1038/383263a0</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/1476-4687">1476-4687</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8805703">8805703</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4339496">4339496</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Role+of+the+inositol+phosphatase+SHIP+in+negative+regulation+of+the+immune+system+by+the+receptor+Fe%CE%B3RIIB&rft.volume=383&rft.issue=6597&rft.pages=263-266&rft.date=1996-09&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4339496%23id-name%3DS2CID&rft_id=info%3Abibcode%2F1996Natur.383..263O&rft.issn=1476-4687&rft_id=info%3Adoi%2F10.1038%2F383263a0&rft_id=info%3Apmid%2F8805703&rft.aulast=Ono&rft.aufirst=Masao&rft.au=Bolland%2C+Silvia&rft.au=Tempst%2C+Paul&rft.au=Ravetch%2C+Jeffrey+V.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASilvia+Bolland" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBollandRavetch2000" class="citation journal cs1">Bolland, Silvia; Ravetch, Jeffrey V (August 2000). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1074-7613%2800%2900027-3">"Spontaneous Autoimmune Disease in FcγRIIB-Deficient Mice Results from Strain-Specific Epistasis"</a>. <i>Immunity</i>. <b>13</b> (2): 277–285. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1074-7613%2800%2900027-3">10.1016/S1074-7613(00)00027-3</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10981970">10981970</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunity&rft.atitle=Spontaneous+Autoimmune+Disease+in+Fc%CE%B3RIIB-Deficient+Mice+Results+from+Strain-Specific+Epistasis&rft.volume=13&rft.issue=2&rft.pages=277-285&rft.date=2000-08&rft_id=info%3Adoi%2F10.1016%2FS1074-7613%2800%2900027-3&rft_id=info%3Apmid%2F10981970&rft.aulast=Bolland&rft.aufirst=Silvia&rft.au=Ravetch%2C+Jeffrey+V&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS1074-7613%252800%252900027-3&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASilvia+Bolland" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRavetchBolland2001" class="citation journal cs1">Ravetch, Jeffrey V.; Bolland, Silvia (April 2001). "IgG Fc Receptors". <i>Annual Review of Immunology</i>. <b>19</b> (1): 275–290. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1146%2Fannurev.immunol.19.1.275">10.1146/annurev.immunol.19.1.275</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0732-0582">0732-0582</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11244038">11244038</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annual+Review+of+Immunology&rft.atitle=IgG+Fc+Receptors&rft.volume=19&rft.issue=1&rft.pages=275-290&rft.date=2001-04&rft.issn=0732-0582&rft_id=info%3Apmid%2F11244038&rft_id=info%3Adoi%2F10.1146%2Fannurev.immunol.19.1.275&rft.aulast=Ravetch&rft.aufirst=Jeffrey+V.&rft.au=Bolland%2C+Silvia&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASilvia+Bolland" class="Z3988"></span></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Silvia_Bolland&action=edit&section=2" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://irp.nih.gov/pi/silvia-bolland">"Silvia M. Bolland, Ph.D. | Principal Investigators | NIH Intramural Research Program"</a>. <i>irp.nih.gov</i><span class="reference-accessdate">. Retrieved <span class="nowrap">2022-11-02</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=irp.nih.gov&rft.atitle=Silvia+M.+Bolland%2C+Ph.D.+%7C+Principal+Investigators+%7C+NIH+Intramural+Research+Program&rft_id=https%3A%2F%2Firp.nih.gov%2Fpi%2Fsilvia-bolland&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASilvia+Bolland" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.niaid.nih.gov/research/silvia-bolland-phd">"Silvia Bolland, Ph.D."</a> <i>NIH: National Institute of Allergy and Infectious Diseases</i>. 30 December 2016<span class="reference-accessdate">. Retrieved <span class="nowrap">2021-01-30</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=NIH%3A+National+Institute+of+Allergy+and+Infectious+Diseases&rft.atitle=Silvia+Bolland%2C+Ph.D.&rft.date=2016-12-30&rft_id=https%3A%2F%2Fwww.niaid.nih.gov%2Fresearch%2Fsilvia-bolland-phd&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASilvia+Bolland" class="Z3988"></span><span class="noviewer" typeof="mw:File"><span><img alt="Public Domain" src="//upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/12px-PD-icon.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/18px-PD-icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/24px-PD-icon.svg.png 2x" data-file-width="196" data-file-height="196" /></span></span> This article incorporates text from this source, which is in the <a href="/wiki/Public_domain" 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