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Reactions to this injection may happen during treatment with GIVLAARI.</p> <p>Tell your doctor or nurse right away if you experience any of the following symptoms of an injection site reaction during treatment: redness, pain, itchiness, rash, discoloration, or swelling around the injection site.</p> </li> <li> <p class="slimbotmarg navy-txt"><strong>Increased blood homocysteine levels</strong></p> <p>GIVLAARI may cause increased levels of homocysteine (a type of amino acid) in your blood. Your doctor will check your homocysteine levels before and during treatment by doing blood tests. If your levels are increased, your doctor may check your folate, vitamins B12 and B6, and tell you to take a vitamin B6 supplement.</p> </li> <li> <p class="slimbotmarg navy-txt"><strong>Inflammation of the pancreas (pancreatitis)</strong></p> <p>Cases of acute pancreatitis including some that were severe, have been reported in patients receiving GIVLAARI. If you have a severe case of acute pancreatitis your doctor or nurse will decide whether to temporarily interrupt or stop treatment with GIVLAARI.</p> </li> </ul> <p class="slimbotmarg navy-txt"><strong>What are the common side effects of GIVLAARI?</strong></p> <p>The most common side effects of GIVLAARI are nausea and injection site reactions. These are not all the possible side effects of GIVLAARI. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a class="warn-on-leave-modal third-party-modal" href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program" target="_blank">www.fda.gov/medwatch</a>, or call <span class="d-inline-block">1-8 00-FDA -1088<span>.</span></span></p> <p class="slimbotmarg teal-txt"><br /> <strong class="purple-txt">WHAT IS GIVLAARI?</strong></p> <p>GIVLAARI is a prescription medicine used to treat acute hepatic porphyria (AHP) in adults.</p> <p class="bold"><br /> For additional information about GIVLAARI, please see full <strong><a href="http://www.alnylam.com/givlaari-us-prescribing-information">Prescribing Information</a></strong>.</p> </div> </div> </div> </div> </div> </div> </div> </main> <div class="region region-footer"> <nav role="navigation" aria-labelledby="block-footer-2-menu" id="block-footer-2" class="block block-menu navigation menu--footer"> <h2 class="visually-hidden" id="block-footer-2-menu">Footer</h2> <footer> <div class="container"> <div class="row"> <div class="col-md-2 col-sm-4 col-6"> <a href="https://www.alnylam.com/" target="_blank"> <img src="/sites/default/files/Alnylam-Footer-Logo.png" title="Alnylam® Pharmaceuticals" alt="Alnylam® Pharmaceuticals logo" class="img-fluid"> </a> </div> <div class="col-sm-6 col-9"> <!-- Start: Copyright --> <div class="copyright"> <div class="footer-logo"> </div> <p class="ml-0"> <span class="questions-call">Questions? 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