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compartmental systems</title> <meta name="description" content="Search results for: compartmental systems"> <meta name="keywords" content="compartmental systems"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="compartmental systems"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 9365</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: compartmental systems</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9365</span> Towards an Enhanced Compartmental Model for Profiling Malware Dynamics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jessemyn%20Modiini">Jessemyn Modiini</a>, <a href="https://publications.waset.org/abstracts/search?q=Timothy%20Lynar"> Timothy Lynar</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20Sitnikova"> Elena Sitnikova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We present a novel enhanced compartmental model for malware spread analysis in cyber security. This paper applies cyber security data features to epidemiological compartmental models to model the infectious potential of malware. Compartmental models are most efficient for calculating the infectious potential of a disease. In this paper, we discuss and profile epidemiologically relevant data features from a Domain Name System (DNS) dataset. We then apply these features to epidemiological compartmental models to network traffic features. This paper demonstrates how epidemiological principles can be applied to the novel analysis of key cybersecurity behaviours and trends and provides insight into threat modelling above that of kill-chain analysis. In applying deterministic compartmental models to a cyber security use case, the authors analyse the deficiencies and provide an enhanced stochastic model for cyber epidemiology. This enhanced compartmental model (SUEICRN model) is contrasted with the traditional SEIR model to demonstrate its efficacy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cybersecurity" title="cybersecurity">cybersecurity</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemiology" title=" epidemiology"> epidemiology</a>, <a href="https://publications.waset.org/abstracts/search?q=cyber%20epidemiology" title=" cyber epidemiology"> cyber epidemiology</a>, <a href="https://publications.waset.org/abstracts/search?q=malware" title=" malware"> malware</a> </p> <a href="https://publications.waset.org/abstracts/152584/towards-an-enhanced-compartmental-model-for-profiling-malware-dynamics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152584.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">107</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9364</span> Time Dependent Biodistribution Modeling of 177Lu-DOTATOC Using Compartmental Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Mousavi-Daramoroudi">M. Mousavi-Daramoroudi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Yousefnia"> H. Yousefnia</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Abbasi-Davani"> F. Abbasi-Davani</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Zolghadri"> S. Zolghadri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, <sup>177</sup>Lu-DOTATOC was prepared under optimized conditions (radiochemical purity: > 99%, radionuclidic purity: > 99%). The percentage of injected dose per gram (%ID/g) was calculated for organs up to 168 h post injection. Compartmental model was applied to mathematical description of the drug behaviour in tissue at different times. The biodistribution data showed the significant excretion of the radioactivity from the kidneys. The adrenal and pancreas, as major expression sites for somatostatin receptor (SSTR), had significant uptake. A pharmacokinetic model of <sup>177</sup>Lu-DOTATOC was presented by compartmental analysis which demonstrates the behavior of the complex. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodistribution" title="biodistribution">biodistribution</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20modeling" title=" compartmental modeling"> compartmental modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B7%E2%81%B7Lu" title=" ¹⁷⁷Lu"> ¹⁷⁷Lu</a>, <a href="https://publications.waset.org/abstracts/search?q=Octreotide" title=" Octreotide"> Octreotide</a> </p> <a href="https://publications.waset.org/abstracts/93824/time-dependent-biodistribution-modeling-of-177lu-dotatoc-using-compartmental-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93824.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">220</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9363</span> Economic Development Process: A Compartmental Analysis of a Model with Two Delays</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amadou%20Banda%20Ndione">Amadou Banda Ndione</a>, <a href="https://publications.waset.org/abstracts/search?q=Charles%20Awono%20Onana"> Charles Awono Onana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper the compartmental approach is applied to build a macroeconomic model characterized by countries. We consider a total of N countries that are subdivided into three compartments according to their economic status: D(t) denotes the compartment of developing countries at time t, E(t) stands for the compartment of emerging countries at time t while A(t) represents advanced countries at time t. The model describes the process of economic development and includes the notion of openness through collaborations between countries. Two delays appear in this model to describe the average time necessary for collaborations between countries to become efficient for their development process. Our model represents the different stages of development. It further gives the conditions under which a country can change its economic status and demonstrates the short-term positive effect of openness on economic growth. In addition, we investigate bifurcation by considering the delay as a bifurcation parameter and examine the onset and termination of Hopf bifurcations from a positive equilibrium. Numerical simulations are provided in order to illustrate the theoretical part and to support discussion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=compartmental%20systems" title="compartmental systems">compartmental systems</a>, <a href="https://publications.waset.org/abstracts/search?q=delayed%20dynamical%20system" title=" delayed dynamical system"> delayed dynamical system</a>, <a href="https://publications.waset.org/abstracts/search?q=economic%20development" title=" economic development"> economic development</a>, <a href="https://publications.waset.org/abstracts/search?q=fiscal%20policy" title=" fiscal policy"> fiscal policy</a>, <a href="https://publications.waset.org/abstracts/search?q=hopf%20bifurcation" title=" hopf bifurcation"> hopf bifurcation</a> </p> <a href="https://publications.waset.org/abstracts/129658/economic-development-process-a-compartmental-analysis-of-a-model-with-two-delays" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/129658.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9362</span> Estimation of Human Absorbed Dose Using Compartmental Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Mousavi-Daramoroudi">M. Mousavi-Daramoroudi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Yousefnia"> H. Yousefnia</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Abbasi-Davani"> F. Abbasi-Davani</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Zolghadri"> S. Zolghadri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dosimetry is an indispensable and precious factor in patient treatment planning to minimize the absorbed dose in vital tissues. In this study, compartmental model was used in order to estimate the human absorbed dose of <sup>177</sup>Lu-DOTATOC from the biodistribution data in wild type rats. For this purpose, <sup>177</sup>Lu-DOTATOC was prepared under optimized conditions and its biodistribution was studied in male Syrian rats up to 168 h. Compartmental model was applied to mathematical description of the drug behaviour in tissue at different times. Dosimetric estimation of the complex was performed using radiation absorbed dose assessment resource (RADAR). The biodistribution data showed high accumulation in the adrenal and pancreas as the major expression sites for somatostatin receptor (SSTR). While kidneys as the major route of excretion receive 0.037 mSv/MBq, pancreas and adrenal also obtain 0.039 and 0.028 mSv/MBq. Due to the usage of this method, the points of accumulated activity data were enhanced, and further information of tissues uptake was collected that it will be followed by high (or improved) precision in dosimetric calculations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=compartmental%20modeling" title="compartmental modeling">compartmental modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20absorbed%20dose" title=" human absorbed dose"> human absorbed dose</a>, <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B7%E2%81%B7Lu-DOTATOC" title=" ¹⁷⁷Lu-DOTATOC"> ¹⁷⁷Lu-DOTATOC</a>, <a href="https://publications.waset.org/abstracts/search?q=Syrian%20rats" title=" Syrian rats"> Syrian rats</a> </p> <a href="https://publications.waset.org/abstracts/94409/estimation-of-human-absorbed-dose-using-compartmental-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/94409.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">193</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9361</span> Compartmental Model Approach for Dosimetric Calculations of ¹⁷⁷Lu-DOTATOC in Adenocarcinoma Breast Cancer Based on Animal Data</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Mousavi-Daramoroudi">M. S. Mousavi-Daramoroudi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Yousefnia"> H. Yousefnia</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Zolghadri"> S. Zolghadri</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Abbasi-Davani"> F. Abbasi-Davani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dosimetry is an indispensable and precious factor in patient treatment planning; to minimize the absorbed dose in vital tissues. In this study, In accordance with the proper characteristics of DOTATOC and ¹⁷⁷Lu, after preparing ¹⁷⁷Lu-DOTATOC at the optimal conditions for the first time in Iran, radionuclidic and radiochemical purity of the solution was investigated using an HPGe spectrometer and ITLC method, respectively. The biodistribution of the compound was assayed for treatment of adenocarcinoma breast cancer in bearing BALB/c mice. The results have demonstrated that ¹⁷⁷Lu-DOTATOC is a profitable selection for therapy of the tumors. Because of the vital role of internal dosimetry before and during therapy, the effort to improve the accuracy and rapidity of dosimetric calculations is necessary. For this reason, a new method was accomplished to calculate the absorbed dose through mixing between compartmental model, animal dosimetry and extrapolated data from animal to human and using MIRD method. Despite utilization of compartmental model based on the experimental data, it seems this approach may increase the accuracy of dosimetric data, confidently. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B7%E2%81%B7Lu-DOTATOC" title="¹⁷⁷Lu-DOTATOC">¹⁷⁷Lu-DOTATOC</a>, <a href="https://publications.waset.org/abstracts/search?q=biodistribution%20modeling" title=" biodistribution modeling"> biodistribution modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20model" title=" compartmental model"> compartmental model</a>, <a href="https://publications.waset.org/abstracts/search?q=internal%20dosimetry" title=" internal dosimetry"> internal dosimetry</a> </p> <a href="https://publications.waset.org/abstracts/74350/compartmental-model-approach-for-dosimetric-calculations-of-177lu-dotatoc-in-adenocarcinoma-breast-cancer-based-on-animal-data" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74350.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">219</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9360</span> Cerebrovascular Modeling: A Vessel Network Approach for Fluid Distribution</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Karla%20E.%20Sanchez-Cazares">Karla E. Sanchez-Cazares</a>, <a href="https://publications.waset.org/abstracts/search?q=Kim%20H.%20Parker"> Kim H. Parker</a>, <a href="https://publications.waset.org/abstracts/search?q=Jennifer%20H.%20Tweedy"> Jennifer H. Tweedy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this work is to develop a simple compartmental model of cerebral fluid balance including blood and cerebrospinal-fluid (CSF). At the first level the cerebral arteries and veins are modelled as bifurcating trees with constant scaling factors between generations which are connected through a homogeneous microcirculation. The arteries and veins are assumed to be non-rigid and the cross-sectional area, resistance and mean pressure in each generation are determined as a function of blood volume flow rate. From the mean pressure and further assumptions about the variation of wall permeability, the transmural fluid flux can be calculated. The results suggest the next level of modelling where the cerebral vasculature is divided into three compartments; the large arteries, the small arteries, the capillaries and the veins with effective compliances and permeabilities derived from the detailed vascular model. These vascular compartments are then linked to other compartments describing the different CSF spaces, the cerebral ventricles and the subarachnoid space. This compartmental model is used to calculate the distribution of fluid in the cranium. Known volumes and flows for normal conditions are used to determine reasonable parameters for the model, which can then be used to help understand pathological behaviour and suggest clinical interventions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cerebrovascular" title="cerebrovascular">cerebrovascular</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20model" title=" compartmental model"> compartmental model</a>, <a href="https://publications.waset.org/abstracts/search?q=CSF%20model" title=" CSF model"> CSF model</a>, <a href="https://publications.waset.org/abstracts/search?q=vascular%20network" title=" vascular network"> vascular network</a> </p> <a href="https://publications.waset.org/abstracts/58673/cerebrovascular-modeling-a-vessel-network-approach-for-fluid-distribution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58673.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">275</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9359</span> Modeling the Time Dependent Biodistribution of a 177Lu Labeled Somatostatin Analogues for Targeted Radiotherapy of Neuroendocrine Tumors Using Compartmental Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahdieh%20Jajroudi">Mahdieh Jajroudi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Developing a pharmacokinetic model for the neuroendocrine tumors therapy agent 177Lu-DOTATATE in nude mice bearing AR42J rat pancreatic tumor to investigate and evaluate the behavior of the complex was the main purpose of this study. The utilization of compartmental analysis permits the mathematical differencing of tissues and organs to become acquainted with the concentration of activity in each fraction of interest. Biodistribution studies are onerous and troublesome to perform in humans, but such data can be obtained facilely in rodents. A physiologically based pharmacokinetic model for scaling up activity concentration in particular organs versus time was developed. The mathematical model exerts physiological parameters including organ volumes, blood flow rates, and vascular permabilities; the compartments (organs) are connected anatomically. This allows the use of scale-up techniques to forecast new complex distribution in humans' each organ. The concentration of the radiopharmaceutical in various organs was measured at different times. The temporal behavior of biodistribution of 177Lu labeled somatostatin analogues was modeled and drawn as function of time. Conclusion: The variation of pharmaceutical concentration in all organs is characterized with summation of six to nine exponential terms and it approximates our experimental data with precision better than 1%. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodistribution%20modeling" title="biodistribution modeling">biodistribution modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20analysis" title=" compartmental analysis"> compartmental analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=177Lu%20labeled%20somatostatin%20analogues" title=" 177Lu labeled somatostatin analogues"> 177Lu labeled somatostatin analogues</a>, <a href="https://publications.waset.org/abstracts/search?q=neuroendocrine%20tumors" title=" neuroendocrine tumors"> neuroendocrine tumors</a> </p> <a href="https://publications.waset.org/abstracts/32538/modeling-the-time-dependent-biodistribution-of-a-177lu-labeled-somatostatin-analogues-for-targeted-radiotherapy-of-neuroendocrine-tumors-using-compartmental-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32538.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">368</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9358</span> Synthesis of Pendent Compartmental Ligand Derived from Polymethacrylate of 3-Formylsalicylic Acid Schiff Base and Its Application Studies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dhivya%20Arumugam">Dhivya Arumugam</a>, <a href="https://publications.waset.org/abstracts/search?q=Kaliyappan%20Thananjeyan"> Kaliyappan Thananjeyan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The monomer of (3-((4-(methacryloyloxy)phenylimino)methyl)-2-hydroxybenzoic acid) schiff base polymer was prepared by reacting methacryloyl chloride with imine compound derived from 3-formylsalisylic acid and 4- aminophenol. The monomer was polymerized in DMF at 70oC using benzoyl peroxide as free radical initiator. Polymer metal complex was obtained in DMF solution of polymer with aqueous solution of metal ions. The polymer and the polymer metal complex were characterized by elemental analysis and spectral studies. The elemental analysis data suggest that the metal to ligand ratio is 1:1 and hence, it acts as a binucleating compartmental ligand. The IR spectral data of these complexes suggest that the metals are coordinated through nitrogen of the imine group, the oxygen of carboxylate ion and the oxygen of the phenolic –OH group which also acts as the bridging ligand. The electronic spectra and magnetic moments of the polychelates shows that octahedral and square planar structure for Ni(II) and Cu(II) complexes respectively. X-ray diffraction studies revealed that polychelates are highly crystalline. The thermal and electrical properties, catalytic activity, structure property relationships are discussed. Further the synthesized polymer was used for metal uptake studies from waste water, which is one of the effective waste water treatment strategies. And also, the polymers and polychelates were investigated for antimicrobial activity with various microorganisms by using agar well diffusion method and the results have been discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acyclic%20compartmental%20ligands" title="acyclic compartmental ligands">acyclic compartmental ligands</a>, <a href="https://publications.waset.org/abstracts/search?q=binucleating%20ligand" title=" binucleating ligand"> binucleating ligand</a>, <a href="https://publications.waset.org/abstracts/search?q=3-formylsalicylic%20acid" title=" 3-formylsalicylic acid"> 3-formylsalicylic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=free%20radical%20polymerization" title=" free radical polymerization"> free radical polymerization</a>, <a href="https://publications.waset.org/abstracts/search?q=polluting%20ions" title=" polluting ions"> polluting ions</a>, <a href="https://publications.waset.org/abstracts/search?q=polychelate" title=" polychelate"> polychelate</a> </p> <a href="https://publications.waset.org/abstracts/150724/synthesis-of-pendent-compartmental-ligand-derived-from-polymethacrylate-of-3-formylsalicylic-acid-schiff-base-and-its-application-studies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150724.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">125</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9357</span> Absorbed Dose Estimation of 177Lu-DOTATOC in Adenocarcinoma Breast Cancer Bearing Mice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Zolghadri">S. Zolghadri</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Mousavi-Daramoroudi"> M. Mousavi-Daramoroudi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Yousefnia"> H. Yousefnia</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Abbasi-Davani"> F. Abbasi-Davani </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the absorbed dose of human organs after injection of <sup>177</sup>Lu-DOTATOC was studied based on the biodistribution of the complex in adenocarcinoma breast cancer bearing mice. For this purpose, the biodistribution of the radiolabelled complex was studied and compartmental modeling was applied to calculate the absorbed dose with high precision. As expected, <sup>177</sup>Lu-DOTATOC illustrated a notable specific uptake in tumor and pancreas, organs with high level of somatostatin receptor on their surface and the effectiveness of the radio-conjugate for targeting of the breast adenocarcinoma tumors was indicated. The elicited results of modeling were the exponential equations, and those are utilized for obtaining the cumulated activity data by taking their integral. The results also exemplified that non-target absorbed-doses such as the liver, spleen and pancreas were approximately 0.008, 0.004, and 0.039, respectively. While these values were so much lower than target (tumor) absorbed-dose, it seems due to this low toxicity, this complex is a good agent for therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B7%E2%81%B7Lu" title="¹⁷⁷Lu">¹⁷⁷Lu</a>, <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title=" breast cancer"> breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20modeling" title=" compartmental modeling"> compartmental modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=dosimetry" title=" dosimetry"> dosimetry</a> </p> <a href="https://publications.waset.org/abstracts/97772/absorbed-dose-estimation-of-177lu-dotatoc-in-adenocarcinoma-breast-cancer-bearing-mice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/97772.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">151</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9356</span> The Impact of City Mobility on Propagation of Infectious Diseases: Mathematical Modelling Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Asrat%20M.Belachew">Asrat M.Belachew</a>, <a href="https://publications.waset.org/abstracts/search?q=Tiago%20Pereira"> Tiago Pereira</a>, <a href="https://publications.waset.org/abstracts/search?q=Institute%20of%20Mathematics"> Institute of Mathematics</a>, <a href="https://publications.waset.org/abstracts/search?q=Computer%20Sciences">Computer Sciences</a>, <a href="https://publications.waset.org/abstracts/search?q=Avenida%20Trabalhador%20S%C3%A3o%20Carlense"> Avenida Trabalhador São Carlense</a>, <a href="https://publications.waset.org/abstracts/search?q=400"> 400</a>, <a href="https://publications.waset.org/abstracts/search?q=S%C3%A3o%20Carlos"> São Carlos</a>, <a href="https://publications.waset.org/abstracts/search?q=13566-590"> 13566-590</a>, <a href="https://publications.waset.org/abstracts/search?q=Brazil"> Brazil</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Infectious diseases are among the most prominent threats to human beings. They cause morbidity and mortality to an individual and collapse the social, economic, and political systems of the whole world collectively. Mathematical models are fundamental tools and provide a comprehensive understanding of how infectious diseases spread and designing the control strategy to mitigate infectious diseases from the host population. Modeling the spread of infectious diseases using a compartmental model of inhomogeneous populations is good in terms of complexity. However, in the real world, there is a situation that accounts for heterogeneity, such as ages, locations, and contact patterns of the population which are ignored in a homogeneous setting. In this work, we study how classical an SEIR infectious disease spreading of the compartmental model can be extended by incorporating the mobility of population between heterogeneous cities during an outbreak of infectious disease. We have formulated an SEIR multi-cities epidemic spreading model using a system of 4k ordinary differential equations to describe the disease transmission dynamics in k-cities during the day and night. We have shownthat the model is epidemiologically (i.e., variables have biological interpretation) and mathematically (i.e., a unique bounded solution exists all the time) well-posed. We constructed the next-generation matrix (NGM) for the model and calculated the basic reproduction number R0for SEIR-epidemic spreading model with cities mobility. R0of the disease depends on the spectral radius mobility operator, and it is a threshold between asymptotic stability of the disease-free equilibrium and disease persistence. Using the eigenvalue perturbation theorem, we showed that sending a fraction of the population between cities decreases the reproduction number of diseases in interconnected cities. As a result, disease transmissiondecreases in the population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SEIR-model" title="SEIR-model">SEIR-model</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20model" title=" mathematical model"> mathematical model</a>, <a href="https://publications.waset.org/abstracts/search?q=city%20mobility" title=" city mobility"> city mobility</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemic%20spreading" title=" epidemic spreading"> epidemic spreading</a> </p> <a href="https://publications.waset.org/abstracts/150894/the-impact-of-city-mobility-on-propagation-of-infectious-diseases-mathematical-modelling-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150894.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">109</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9355</span> Analysis of the Dynamics of Transmission of Microsporidia MB Inside the Population of Anopheles Mosquitoes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Charlene%20N.%20T.%20Mfangnia">Charlene N. T. Mfangnia</a>, <a href="https://publications.waset.org/abstracts/search?q=Henri%20Tonnang"> Henri Tonnang</a>, <a href="https://publications.waset.org/abstracts/search?q=Berge%20Tsanou"> Berge Tsanou</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Herren"> Jeremy Herren</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Microsporidia MB found in the populations of anopheles is a recently discovered symbiont responsible for the Plasmodium transmission blocking. From early studies, it was established that the symbiont can be transmitted vertically and horizontally. The present study uses compartmental mathematical modelling approach to investigate the dynamics of Microsporidia transmission in the mosquito population with the mindset of establishing a mechanism for use to control malaria. Data and information obtained from laboratory experiments are used to estimate the model parameters with and without temperature dependency of mosquito traits. We carry out the mathematical analysis focusing on the equilibria states and their stability for the autonomous model. Through the modelling experiments, we are able to assess and confirm the contribution of vertical and horizontal transmission in the proliferation of Microsporidia MB in the mosquito population. In addition, the basic and target reproductions are computed, and some long-term behaviours of the model, such as the local (and global) stability of equilibrium points, are rigorously analysed and illustrated numerically. We establish the conditions responsible for the low prevalence of the symbiont-infected mosquitoes observed in nature. Moreover, we identify the male death rate, the mating rate and the attractiveness of MB-positive mosquitoes as mosquito traits that significantly influence the spread of Microsporidia MB. Furthermore, we highlight the influence of temperature in the establishment and persistence of MB-infected mosquitoes in a given area. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=microsporidia%20MB" title="microsporidia MB">microsporidia MB</a>, <a href="https://publications.waset.org/abstracts/search?q=vertical%20transmission" title=" vertical transmission"> vertical transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=horizontal%20transmission" title=" horizontal transmission"> horizontal transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20modelling%20approach" title=" compartmental modelling approach"> compartmental modelling approach</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature-dependent%20mosquito%20traits" title=" temperature-dependent mosquito traits"> temperature-dependent mosquito traits</a>, <a href="https://publications.waset.org/abstracts/search?q=malaria" title=" malaria"> malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=plasmodium-transmission%20blocking" title=" plasmodium-transmission blocking"> plasmodium-transmission blocking</a> </p> <a href="https://publications.waset.org/abstracts/161357/analysis-of-the-dynamics-of-transmission-of-microsporidia-mb-inside-the-population-of-anopheles-mosquitoes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161357.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9354</span> Model and Neural Control of the Depth of Anesthesia during Surgery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Javier%20Fernandez">Javier Fernandez</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayte%20Medina"> Mayte Medina</a>, <a href="https://publications.waset.org/abstracts/search?q=Rafael%20Fernandez%20de%20Canete"> Rafael Fernandez de Canete</a>, <a href="https://publications.waset.org/abstracts/search?q=Nuria%20Alcain"> Nuria Alcain</a>, <a href="https://publications.waset.org/abstracts/search?q=Juan%20Carlos%20Ramos-Diaz"> Juan Carlos Ramos-Diaz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> At present, the experimentation of anesthetic drugs on patients requires a regulation protocol, and the response of each patient to several doses of entry drug must be well known. Therefore, the development of pharmacological dose control systems is a promising field of research in anesthesiology. In this paper, it has been developed a non-linear compartmental the pharmacokinetic-pharmacodynamical model which describes the anesthesia depth effect in a sufficiently reliable way over a set of patients with the depth effect quantified by the Bi-Spectral Index. Afterwards, an Artificial Neural Network (ANN) predictive controller has been designed based on the depth of anesthesia model so as to keep the patient in the optimum condition while he undergoes surgical treatment. For the purpose of quantifying the efficiency of the neural predictive controller, a classical proportional-integral-derivative controller has also been developed to compare both strategies. Results show the superior performance of predictive neural controller during BiSpectral Index reference tracking. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anesthesia" title="anesthesia">anesthesia</a>, <a href="https://publications.waset.org/abstracts/search?q=bi-spectral%20index" title=" bi-spectral index"> bi-spectral index</a>, <a href="https://publications.waset.org/abstracts/search?q=neural%20network%20control" title=" neural network control"> neural network control</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmacokinetic-pharmacodynamical%20model" title=" pharmacokinetic-pharmacodynamical model"> pharmacokinetic-pharmacodynamical model</a> </p> <a href="https://publications.waset.org/abstracts/87956/model-and-neural-control-of-the-depth-of-anesthesia-during-surgery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/87956.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">336</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9353</span> A Dynamical Study of Fractional Order Obesity Model by a Combined Legendre Wavelet Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hakiki%20Kheira">Hakiki Kheira</a>, <a href="https://publications.waset.org/abstracts/search?q=Belhamiti%20Omar"> Belhamiti Omar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, we propose a new compartmental fractional order model for the simulation of epidemic obesity dynamics. Using the Legendre wavelet method combined with the decoupling and quasi-linearization technique, we demonstrate the validity and applicability of our model. We also present some fractional differential illustrative examples to demonstrate the applicability and efficiency of the method. The fractional derivative is described in the Caputo sense. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Caputo%20derivative" title="Caputo derivative">Caputo derivative</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemiology" title=" epidemiology"> epidemiology</a>, <a href="https://publications.waset.org/abstracts/search?q=Legendre%20wavelet%20method" title=" Legendre wavelet method"> Legendre wavelet method</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity "> obesity </a> </p> <a href="https://publications.waset.org/abstracts/42731/a-dynamical-study-of-fractional-order-obesity-model-by-a-combined-legendre-wavelet-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42731.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">420</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9352</span> Multiscale Modelling of Citrus Black Spot Transmission Dynamics along the Pre-Harvest Supply Chain</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muleya%20Nqobile">Muleya Nqobile</a>, <a href="https://publications.waset.org/abstracts/search?q=Winston%20Garira"> Winston Garira</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We presented a compartmental deterministic multi-scale model which encompass internal plant defensive mechanism and pathogen interaction, then we consider nesting the model into the epidemiological model. The objective was to improve our understanding of the transmission dynamics of within host and between host of Guignardia citricapa Kiely. The inflow of infected class was scaled down to individual level while the outflow was scaled up to average population level. Conceptual model and mathematical model were constructed to display a theoretical framework which can be used for predicting or identify disease pattern. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=epidemiological%20model" title="epidemiological model">epidemiological model</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20modelling" title=" mathematical modelling"> mathematical modelling</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-scale%20modelling" title=" multi-scale modelling"> multi-scale modelling</a>, <a href="https://publications.waset.org/abstracts/search?q=immunological%20model" title=" immunological model"> immunological model</a> </p> <a href="https://publications.waset.org/abstracts/52713/multiscale-modelling-of-citrus-black-spot-transmission-dynamics-along-the-pre-harvest-supply-chain" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52713.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">458</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9351</span> A Mathematical Model for Hepatitis B Virus Infection and the Impact of Vaccination on Its Dynamics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20G.%20Kassem">T. G. Kassem</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20K.%20Adunchezor"> A. K. Adunchezor</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20P.%20Chollom"> J. P. Chollom</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper describes a mathematical model developed to predict the dynamics of Hepatitis B virus (HBV) infection and to evaluate the potential impact of vaccination and treatment on its dynamics. We used a compartmental model expressed by a set of differential equations based on the characteristic of HBV transmission. With these, we find the threshold quantity R0, then find the local asymptotic stability of disease free equilibrium and endemic equilibrium. Furthermore, we find the global stability of the disease free and endemic equilibrium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hepatitis%20B%20virus" title="hepatitis B virus">hepatitis B virus</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemiology" title=" epidemiology"> epidemiology</a>, <a href="https://publications.waset.org/abstracts/search?q=vaccination" title=" vaccination"> vaccination</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20model" title=" mathematical model"> mathematical model</a> </p> <a href="https://publications.waset.org/abstracts/6070/a-mathematical-model-for-hepatitis-b-virus-infection-and-the-impact-of-vaccination-on-its-dynamics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6070.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">324</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9350</span> Impact of Tourists on HIV (Human Immunodeficiency Virus) Incidence</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ofosuhene%20O.%20Apenteng">Ofosuhene O. Apenteng</a>, <a href="https://publications.waset.org/abstracts/search?q=Noor%20Azina%20Ismail"> Noor Azina Ismail</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Recently tourism is a major foreign exchange earner in the World. In this paper, we propose the mathematical model to study the impact of tourists on the spread of HIV incidences using compartmental differential equation models. Simulation studies of reproduction number are used to demonstrate new insights on the spread of HIV disease. The periodogram analysis of a time series was used to determine the speed at which the disease is spread. The results indicate that with the persistent flow of tourism into a country, the disease status has increased the epidemic rate. The result suggests that the government must put more control on illegal prostitution, unprotected sexual activity as well as to emphasis on prevention policies that include the safe sexual activity through the campaign by the tourism board. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HIV%2FAIDS" title="HIV/AIDS">HIV/AIDS</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20transmission%20modeling" title=" mathematical transmission modeling"> mathematical transmission modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=tourists" title=" tourists"> tourists</a>, <a href="https://publications.waset.org/abstracts/search?q=stability" title=" stability"> stability</a>, <a href="https://publications.waset.org/abstracts/search?q=simulation" title=" simulation "> simulation </a> </p> <a href="https://publications.waset.org/abstracts/37089/impact-of-tourists-on-hiv-human-immunodeficiency-virus-incidence" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37089.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">391</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9349</span> Connecting MRI Physics to Glioma Microenvironment: Comparing Simulated T2-Weighted MRI Models of Fixed and Expanding Extracellular Space</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pamela%20R.%20%20Jackson">Pamela R. Jackson</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Hawkins-Daarud"> Andrea Hawkins-Daarud</a>, <a href="https://publications.waset.org/abstracts/search?q=Cassandra%20R.%20%20Rickertsen"> Cassandra R. Rickertsen</a>, <a href="https://publications.waset.org/abstracts/search?q=Kamala%20Clark-Swanson"> Kamala Clark-Swanson</a>, <a href="https://publications.waset.org/abstracts/search?q=Scott%20A.%20%20Whitmire"> Scott A. Whitmire</a>, <a href="https://publications.waset.org/abstracts/search?q=Kristin%20R.%20%20Swanson"> Kristin R. Swanson</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glioblastoma Multiforme (GBM), the most common primary brain tumor, often presents with hyperintensity on T2-weighted or T2-weighted fluid attenuated inversion recovery (T2/FLAIR) magnetic resonance imaging (MRI). This hyperintensity corresponds with vasogenic edema, however there are likely many infiltrating tumor cells within the hyperintensity as well. While MRIs do not directly indicate tumor cells, MRIs do reflect the microenvironmental water abnormalities caused by the presence of tumor cells and edema. The inherent heterogeneity and resulting MRI features of GBMs complicate assessing disease response. To understand how hyperintensity on T2/FLAIR MRI may correlate with edema in the extracellular space (ECS), a multi-compartmental MRI signal equation which takes into account tissue compartments and their associated volumes with input coming from a mathematical model of glioma growth that incorporates edema formation was explored. The reasonableness of two possible extracellular space schema was evaluated by varying the T2 of the edema compartment and calculating the possible resulting T2s in tumor and peripheral edema. In the mathematical model, gliomas were comprised of vasculature and three tumor cellular phenotypes: normoxic, hypoxic, and necrotic. Edema was characterized as fluid leaking from abnormal tumor vessels. Spatial maps of tumor cell density and edema for virtual tumors were simulated with different rates of proliferation and invasion and various ECS expansion schemes. These spatial maps were then passed into a multi-compartmental MRI signal model for generating simulated T2/FLAIR MR images. Individual compartments’ T2 values in the signal equation were either from literature or estimated and the T2 for edema specifically was varied over a wide range (200 ms – 9200 ms). T2 maps were calculated from simulated images. T2 values based on simulated images were evaluated for regions of interest (ROIs) in normal appearing white matter, tumor, and peripheral edema. The ROI T2 values were compared to T2 values reported in literature. The expanding scheme of extracellular space is had T2 values similar to the literature calculated values. The static scheme of extracellular space had a much lower T2 values and no matter what T2 was associated with edema, the intensities did not come close to literature values. Expanding the extracellular space is necessary to achieve simulated edema intensities commiserate with acquired MRIs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=extracellular%20space" title="extracellular space">extracellular space</a>, <a href="https://publications.waset.org/abstracts/search?q=glioblastoma%20multiforme" title=" glioblastoma multiforme"> glioblastoma multiforme</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20resonance%20imaging" title=" magnetic resonance imaging"> magnetic resonance imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20modeling" title=" mathematical modeling"> mathematical modeling</a> </p> <a href="https://publications.waset.org/abstracts/67871/connecting-mri-physics-to-glioma-microenvironment-comparing-simulated-t2-weighted-mri-models-of-fixed-and-expanding-extracellular-space" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67871.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">235</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9348</span> Cardiovascular Modeling Software Tools in Medicine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20Fernandez">J. Fernandez</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Fernandez%20de%20Canete"> R. Fernandez de Canete</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Perea-Paizal"> J. Perea-Paizal</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20C.%20Ramos-Diaz"> J. C. Ramos-Diaz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The high prevalence of cardiovascular diseases has provoked a raising interest in the development of mathematical models in order to evaluate the cardiovascular function both under physiological and pathological conditions. In this paper, a physical model of the cardiovascular system with intrinsic regulation is presented and implemented by using the object-oriented Modelica simulation software tools.  For this task, a multi-compartmental system previously validated with physiological data has been built, based on the interconnection of cardiovascular elements such as resistances, capacitances and pumping among others, by following an electrohydraulic analogy. The results obtained under both physiological and pathological scenarios provide an easy interpretative key to analyze the hemodynamic behavior of the patient. The described approach represents a valuable tool in the teaching of physiology for graduate medical and nursing students among others. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiovascular%20system" title="cardiovascular system">cardiovascular system</a>, <a href="https://publications.waset.org/abstracts/search?q=MODELICA%20simulation%20software" title=" MODELICA simulation software"> MODELICA simulation software</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20modelling" title=" physical modelling"> physical modelling</a>, <a href="https://publications.waset.org/abstracts/search?q=teaching%20tool" title=" teaching tool"> teaching tool</a> </p> <a href="https://publications.waset.org/abstracts/72982/cardiovascular-modeling-software-tools-in-medicine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72982.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">300</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9347</span> A Time since of Injection Model for Hepatitis C Amongst People Who Inject Drugs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nader%20Al-Rashidi">Nader Al-Rashidi</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20Greenhalgh"> David Greenhalgh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mathematical modelling techniques are now being used by health organizations worldwide to help understand the likely impact that intervention strategies treatment options and combinations of these have on the prevalence and incidence of hepatitis C virus (HCV) in the people who inject drugs (PWID) population. In this poster, we develop a deterministic, compartmental mathematical model to approximate the spread of the HCV in a PWID population that has been divided into two groups by time since onset of injection. The model assumes that after injection needles adopt the most infectious state of their previous state or that of the PWID who last injected with them. Using analytical techniques, we find that the model behaviour is determined by the basic reproductive number R₀, where R₀ = 1 is a critical threshold separating two different outcomes. The disease-free equilibrium is globally stable if R₀ ≤ 1 and unstable if R₀ > 1. Additionally, we make some simulations where have confirmed that the model tends to this endemic equilibrium value with realistic parameter values giving an HCV prevalence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hepatitis%20C" title="hepatitis C">hepatitis C</a>, <a href="https://publications.waset.org/abstracts/search?q=people%20who%20inject%20drugs" title=" people who inject drugs"> people who inject drugs</a>, <a href="https://publications.waset.org/abstracts/search?q=HCV" title=" HCV"> HCV</a>, <a href="https://publications.waset.org/abstracts/search?q=PWID" title=" PWID"> PWID</a> </p> <a href="https://publications.waset.org/abstracts/107638/a-time-since-of-injection-model-for-hepatitis-c-amongst-people-who-inject-drugs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/107638.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">144</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9346</span> A Data-Driven Compartmental Model for Dengue Forecasting and Covariate Inference</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yichao%20Liu">Yichao Liu</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Fransson"> Peter Fransson</a>, <a href="https://publications.waset.org/abstracts/search?q=Julian%20Heidecke"> Julian Heidecke</a>, <a href="https://publications.waset.org/abstracts/search?q=Jonas%20Wallin"> Jonas Wallin</a>, <a href="https://publications.waset.org/abstracts/search?q=Joacim%20Rockloev"> Joacim Rockloev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dengue, a mosquito-borne viral disease, poses a significant public health challenge in endemic tropical or subtropical countries, including Sri Lanka. To reveal insights into the complexity of the dynamics of this disease and study the drivers, a comprehensive model capable of both robust forecasting and insightful inference of drivers while capturing the co-circulating of several virus strains is essential. However, existing studies mostly focus on only one aspect at a time and do not integrate and carry insights across the siloed approach. While mechanistic models are developed to capture immunity dynamics, they are often oversimplified and lack integration of all the diverse drivers of disease transmission. On the other hand, purely data-driven methods lack constraints imposed by immuno-epidemiological processes, making them prone to overfitting and inference bias. This research presents a hybrid model that combines machine learning techniques with mechanistic modelling to overcome the limitations of existing approaches. Leveraging eight years of newly reported dengue case data, along with socioeconomic factors, such as human mobility, weekly climate data from 2011 to 2018, genetic data detecting the introduction and presence of new strains, and estimates of seropositivity for different districts in Sri Lanka, we derive a data-driven vector (SEI) to human (SEIR) model across 16 regions in Sri Lanka at the weekly time scale. By conducting ablation studies, the lag effects allowing delays up to 12 weeks of time-varying climate factors were determined. The model demonstrates superior predictive performance over a pure machine learning approach when considering lead times of 5 and 10 weeks on data withheld from model fitting. It further reveals several interesting interpretable findings of drivers while adjusting for the dynamics and influences of immunity and introduction of a new strain. The study uncovers strong influences of socioeconomic variables: population density, mobility, household income and rural vs. urban population. The study reveals substantial sensitivity to the diurnal temperature range and precipitation, while mean temperature and humidity appear less important in the study location. Additionally, the model indicated sensitivity to vegetation index, both max and average. Predictions on testing data reveal high model accuracy. Overall, this study advances the knowledge of dengue transmission in Sri Lanka and demonstrates the importance of incorporating hybrid modelling techniques to use biologically informed model structures with flexible data-driven estimates of model parameters. The findings show the potential to both inference of drivers in situations of complex disease dynamics and robust forecasting models. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=compartmental%20model" title="compartmental model">compartmental model</a>, <a href="https://publications.waset.org/abstracts/search?q=climate" title=" climate"> climate</a>, <a href="https://publications.waset.org/abstracts/search?q=dengue" title=" dengue"> dengue</a>, <a href="https://publications.waset.org/abstracts/search?q=machine%20learning" title=" machine learning"> machine learning</a>, <a href="https://publications.waset.org/abstracts/search?q=social-economic" title=" social-economic"> social-economic</a> </p> <a href="https://publications.waset.org/abstracts/169664/a-data-driven-compartmental-model-for-dengue-forecasting-and-covariate-inference" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169664.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">84</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9345</span> Modeling and Optimal Control of Pneumonia Disease with Cost Effective Strategies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Getachew%20Tilahun">Getachew Tilahun</a>, <a href="https://publications.waset.org/abstracts/search?q=Oluwole%20Makinde"> Oluwole Makinde</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20Malonza"> David Malonza</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We propose and analyze a non-linear mathematical model for the transmission dynamics of pneumonia disease in a population of varying size. The deterministic compartmental model is studied using stability theory of differential equations. The effective reproduction number is obtained and also the local and global asymptotically stability conditions for the disease free and as well as for the endemic equilibria are established. The model exhibit a backward bifurcation and the sensitivity indices of the basic reproduction number to the key parameters are determined. Using Pontryagin’s maximum principle, the optimal control problem is formulated with three control strategies; namely disease prevention through education, treatment and screening. The cost effectiveness analysis of the adopted control strategies revealed that the combination of prevention and treatment is the most cost effective intervention strategies to combat the pneumonia pandemic. Numerical simulation is performed and pertinent results are displayed graphically. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cost%20effectiveness%20analysis" title="cost effectiveness analysis">cost effectiveness analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=optimal%20control" title=" optimal control"> optimal control</a>, <a href="https://publications.waset.org/abstracts/search?q=pneumonia%20dynamics" title=" pneumonia dynamics"> pneumonia dynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=stability%20analysis" title=" stability analysis"> stability analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20simulation" title=" numerical simulation"> numerical simulation</a> </p> <a href="https://publications.waset.org/abstracts/61514/modeling-and-optimal-control-of-pneumonia-disease-with-cost-effective-strategies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61514.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">326</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9344</span> Artificial Intelligence in Enterprise Information Systems: A Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Danah%20S.%20Alabdulmohsin">Danah S. Alabdulmohsin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Due to the fast growth of organizational data as well as the emergence of new technologies such as artificial intelligence (AI), organizations tend to utilize these new technologies in their enterprise information systems (EIS) either to overcome the issues they struggle with or to enhance their functions. The aim of this paper is to review the potential role of AI technologies in EIS, namely: enterprise resource planning systems (ERP), customer relation management systems (CRM), supply chain management systems (SCM), knowledge systems (KM), and human resources management systems (HRM). The paper provided the definitions of these systems as well as the definitions of AI technologies that have been used in EIS. In addition, the paper discussed the challenges that organizations might face while integrating AI with their information systems and explained why some organizations fail in achieving successful implementations of the integration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20intelligence" title="artificial intelligence">artificial intelligence</a>, <a href="https://publications.waset.org/abstracts/search?q=AI" title=" AI"> AI</a>, <a href="https://publications.waset.org/abstracts/search?q=enterprise%20information%20system" title=" enterprise information system"> enterprise information system</a>, <a href="https://publications.waset.org/abstracts/search?q=EIS" title=" EIS"> EIS</a>, <a href="https://publications.waset.org/abstracts/search?q=integration" title=" integration"> integration</a> </p> <a href="https://publications.waset.org/abstracts/152803/artificial-intelligence-in-enterprise-information-systems-a-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152803.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">97</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9343</span> Non-Autonomous Seasonal Variation Model for Vector-Borne Disease Transferral in Kampala of Uganda</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Benjamin%20Aina%20Peter">Benjamin Aina Peter</a>, <a href="https://publications.waset.org/abstracts/search?q=Amos%20Wale%20Ogunsola"> Amos Wale Ogunsola</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, a mathematical model of malaria transmission was presented with the effect of seasonal shift, due to global fluctuation in temperature, on the increase of conveyor of the infectious disease, which probably alters the region transmission potential of malaria. A deterministic compartmental model was proposed and analyzed qualitatively. Both qualitative and quantitative approaches of the model were considered. The next-generation matrix is employed to determine the basic reproduction number of the model. Equilibrium points of the model were determined and analyzed. The numerical simulation is carried out using Excel Micro Software to validate and support the qualitative results. From the analysis of the result, the optimal temperature for the transmission of malaria is between and . The result also shows that an increase in temperature due to seasonal shift gives rise to the development of parasites which consequently leads to an increase in the widespread of malaria transmission in Kampala. It is also seen from the results that an increase in temperature leads to an increase in the number of infectious human hosts and mosquitoes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=seasonal%20variation" title="seasonal variation">seasonal variation</a>, <a href="https://publications.waset.org/abstracts/search?q=indoor%20residual%20spray" title=" indoor residual spray"> indoor residual spray</a>, <a href="https://publications.waset.org/abstracts/search?q=efficacy%20of%20spray" title=" efficacy of spray"> efficacy of spray</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature-dependent%20model" title=" temperature-dependent model"> temperature-dependent model</a> </p> <a href="https://publications.waset.org/abstracts/143261/non-autonomous-seasonal-variation-model-for-vector-borne-disease-transferral-in-kampala-of-uganda" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143261.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">169</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9342</span> Research on the Application of Flexible and Programmable Systems in Electronic Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yang%20Xiaodong">Yang Xiaodong</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This article explores the application and structural characteristics of flexible and programmable systems in electronic systems, with a focus on analyzing their advantages and architectural differences in dealing with complex environments. By introducing mathematical models and simulation experiments, the performance of dynamic module combination in flexible systems and fixed path selection in programmable systems in resource utilization and performance optimization was demonstrated. This article also discusses the mutual transformation between the two in practical applications and proposes a solution to improve system flexibility and performance through dynamic reconfiguration technology. This study provides theoretical reference for the design and optimization of flexible and programmable systems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=flexibility" title="flexibility">flexibility</a>, <a href="https://publications.waset.org/abstracts/search?q=programmable" title=" programmable"> programmable</a>, <a href="https://publications.waset.org/abstracts/search?q=electronic%20systems" title=" electronic systems"> electronic systems</a>, <a href="https://publications.waset.org/abstracts/search?q=system%20architecture" title=" system architecture"> system architecture</a> </p> <a href="https://publications.waset.org/abstracts/193856/research-on-the-application-of-flexible-and-programmable-systems-in-electronic-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193856.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">8</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9341</span> Integration of Climatic Factors in the Meta-Population Modelling of the Dynamic of Malaria Transmission, Case of Douala and Yaoundé, Two Cities of Cameroon</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Justin-Herve%20Noubissi">Justin-Herve Noubissi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean%20Claude%20Kamgang"> Jean Claude Kamgang</a>, <a href="https://publications.waset.org/abstracts/search?q=Eric%20Ramat"> Eric Ramat</a>, <a href="https://publications.waset.org/abstracts/search?q=Januarius%20Asongu"> Januarius Asongu</a>, <a href="https://publications.waset.org/abstracts/search?q=Christophe%20Cambier"> Christophe Cambier</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The goal of our study is to analyse the impact of climatic factors in malaria transmission taking into account migration between Douala and Yaoundé, two cities of Cameroon country. We show how variations of climatic factors such as temperature and relative humidity affect the malaria spread. We propose a meta-population model of the dynamic transmission of malaria that evolves in space and time and that takes into account temperature and relative humidity and the migration between Douala and Yaoundé. We also integrate the variation of environmental factors as events also called mathematical impulsion that can disrupt the model evolution at any time. Our modelling has been done using the Discrete EVents System Specification (DEVS) formalism. Our implementation has been done on Virtual Laboratory Environment (VLE) that uses DEVS formalism and abstract simulators for coupling models by integrating the concept of DEVS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=compartmental%20models" title="compartmental models">compartmental models</a>, <a href="https://publications.waset.org/abstracts/search?q=DEVS" title=" DEVS"> DEVS</a>, <a href="https://publications.waset.org/abstracts/search?q=discrete%20events" title=" discrete events"> discrete events</a>, <a href="https://publications.waset.org/abstracts/search?q=meta-population%20model" title=" meta-population model"> meta-population model</a>, <a href="https://publications.waset.org/abstracts/search?q=VLE" title=" VLE"> VLE</a> </p> <a href="https://publications.waset.org/abstracts/52388/integration-of-climatic-factors-in-the-meta-population-modelling-of-the-dynamic-of-malaria-transmission-case-of-douala-and-yaounde-two-cities-of-cameroon" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52388.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">554</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9340</span> Commutativity of Fractional Order Linear Time-Varying Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Salisu%20Ibrahim">Salisu Ibrahim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper studies the commutativity associated with fractional order linear time-varying systems (LTVSs), which is an important area of study in control systems engineering. In this paper, we explore the properties of these systems and their ability to commute. We proposed the necessary and sufficient condition for commutativity for fractional order LTVSs. Through a simulation and mathematical analysis, we demonstrate that these systems exhibit commutativity under certain conditions. Our findings have implications for the design and control of fractional order systems in practical applications, science, and engineering. An example is given to show the effectiveness of the proposed method which is been computed by Mathematica and validated by the use of MATLAB (Simulink). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fractional%20differential%20equation" title="fractional differential equation">fractional differential equation</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20systems" title=" physical systems"> physical systems</a>, <a href="https://publications.waset.org/abstracts/search?q=equivalent%20circuit" title=" equivalent circuit"> equivalent circuit</a>, <a href="https://publications.waset.org/abstracts/search?q=analog%20control" title=" analog control"> analog control</a> </p> <a href="https://publications.waset.org/abstracts/171951/commutativity-of-fractional-order-linear-time-varying-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171951.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">114</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9339</span> Productivity and Structural Design of Manufacturing Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ryspek%20Usubamatov">Ryspek Usubamatov</a>, <a href="https://publications.waset.org/abstracts/search?q=Tan%20San%20Chin"> Tan San Chin</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarken%20Kapaeva"> Sarken Kapaeva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Productivity of the manufacturing systems depends on technological processes, a technical data of machines and a structure of systems. Technology is presented by the machining mode and data, a technical data presents reliability parameters and auxiliary time for discrete production processes. The term structure of manufacturing systems includes the number of serial and parallel production machines and links between them. Structures of manufacturing systems depend on the complexity of technological processes. Mathematical models of productivity rate for manufacturing systems are important attributes that enable to define best structure by criterion of a productivity rate. These models are important tool in evaluation of the economical efficiency for production systems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=productivity" title="productivity">productivity</a>, <a href="https://publications.waset.org/abstracts/search?q=structure" title=" structure"> structure</a>, <a href="https://publications.waset.org/abstracts/search?q=manufacturing%20systems" title=" manufacturing systems"> manufacturing systems</a>, <a href="https://publications.waset.org/abstracts/search?q=structural%20design" title=" structural design"> structural design</a> </p> <a href="https://publications.waset.org/abstracts/3403/productivity-and-structural-design-of-manufacturing-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3403.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">583</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9338</span> A Project-Orientated Training Concept to Prepare Students for Systems Engineering Activities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elke%20Mackensen">Elke Mackensen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Systems Engineering plays a key role during industrial product development of complex technical systems. The need for systems engineers in industry is growing. However, there is a gap between the industrial need and the academic education. Normally the academic education is focused on the domain specific design, implementation and testing of technical systems. Necessary systems engineering expertise like knowledge about requirements analysis, product cost estimation, management or social skills are poorly taught. Thus, there is the need of new academic concepts for teaching systems engineering skills. This paper presents a project-orientated training concept to prepare students from different technical degree programs for systems engineering activities. The training concept has been initially implemented and applied in the industrial engineering master program of the University of Applied Sciences Offenburg. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=educational%20systems%20engineering%20training" title="educational systems engineering training">educational systems engineering training</a>, <a href="https://publications.waset.org/abstracts/search?q=requirements%20analysis" title=" requirements analysis"> requirements analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=system%20modelling" title=" system modelling"> system modelling</a>, <a href="https://publications.waset.org/abstracts/search?q=SysML" title=" SysML"> SysML</a> </p> <a href="https://publications.waset.org/abstracts/14859/a-project-orientated-training-concept-to-prepare-students-for-systems-engineering-activities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14859.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">346</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9337</span> A Survey on Linear Time Invariant Multivariable Positive Real Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mojtaba%20Hakimi-Moghaddam">Mojtaba Hakimi-Moghaddam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Positive realness as the most important property of driving point impedance of passive electrical networks appears in the control systems stability theory in 1960’s. There are three important subsets of positive real (PR) systems are introduced by researchers, that is, loos-less positive real (LLPR) systems, weakly strictly positive real (WSPR) systems and strictly positive real (SPR) systems. In this paper, definitions, properties, lemmas, and theorems related to family of positive real systems are summarized. Properties in both frequency domain and state space representation of system are explained. Also, several illustrative examples are presented. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=real%20rational%20matrix%20transfer%20functions" title="real rational matrix transfer functions">real rational matrix transfer functions</a>, <a href="https://publications.waset.org/abstracts/search?q=positive%20realness%20property" title=" positive realness property"> positive realness property</a>, <a href="https://publications.waset.org/abstracts/search?q=strictly%20positive%20realness%20property" title=" strictly positive realness property"> strictly positive realness property</a>, <a href="https://publications.waset.org/abstracts/search?q=Hermitian%20form%20asymptotic%20property" title=" Hermitian form asymptotic property"> Hermitian form asymptotic property</a>, <a href="https://publications.waset.org/abstracts/search?q=pole-zero%20properties" title=" pole-zero properties"> pole-zero properties</a> </p> <a href="https://publications.waset.org/abstracts/72983/a-survey-on-linear-time-invariant-multivariable-positive-real-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72983.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">274</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9336</span> Enterprise Risk Management, Human Capital and Organizational Performance: Insights from Public Listed Companies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Omar%20Moafaq%20Saleh%20Aljanabi">Omar Moafaq Saleh Aljanabi</a>, <a href="https://publications.waset.org/abstracts/search?q=Noradiva%20Hamzah"> Noradiva Hamzah</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruhanita%20Maelah"> Ruhanita Maelah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In today’s challenging global economy, which is driven by information and knowledge, risk management is undergoing a great change, as organizations shift from traditional and compartmental risk management to an enterprise-wide approach. Enterprise risk management (ERM), which aims at increasing the sustainability of an organization and achieving competitive advantage, is gaining global attention and fast becoming an essential concern in all industries. Furthermore, in order to be effective, ERM should be managed by managers with high-level skills and knowledge. Despite the importance of the knowledge embedded in, there remains a paucity of evidence concerning how human capital could influence the organization’s ERM. Responses from 116 public listed companies (PLCs) on the main market of Bursa Malaysia were analyzed using Structural Equation Modelling (SEM). This study found that there is a significant association between ERM and organizational performance. The results also indicate that human capital has a positive moderating effect on the relationship between ERM and performance. The study contributes to the ERM literature by providing empirical evidence on the relationship between ERM, human capital, and organizational performance. Findings from this study also provide guidelines for managers, policy makers, and the regulatory bodies, to evaluate the ERM practices in PLCs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enterprise%20risk%20management" title="enterprise risk management">enterprise risk management</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20capital" title=" human capital"> human capital</a>, <a href="https://publications.waset.org/abstracts/search?q=organizational%20performance" title=" organizational performance"> organizational performance</a>, <a href="https://publications.waset.org/abstracts/search?q=Malaysian%20public%20listed%20companies" title=" Malaysian public listed companies "> Malaysian public listed companies </a> </p> <a href="https://publications.waset.org/abstracts/87557/enterprise-risk-management-human-capital-and-organizational-performance-insights-from-public-listed-companies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/87557.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">195</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=compartmental%20systems&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=compartmental%20systems&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=compartmental%20systems&page=4">4</a></li> <li class="page-item"><a class="page-link" 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