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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8" /> <title>Mendelian laws apply to human beings :: DNA from the Beginning</title> <meta name="description" content="Family pedigrees provided evidence of Mendelian inheritance in humans." /> <link rel="preload" as="style" src="/css/main.css"> <link rel="preload" as="script" src="/js/swfobject.js"> <link rel="preload" as="script" src="/js/prototype-1.6.1.js"> <link href="/css/main.css" rel="stylesheet" type="text/css" /> <link href='https://fonts.googleapis.com/css?family=Droid+Serif' rel='stylesheet' type='text/css'/> <link href='https://fonts.googleapis.com/css?family=Droid+Sans' rel='stylesheet' type='text/css'/> <script type="text/javascript" src="/js/swfobject.js"></script> <script type="text/javascript" src="/js/prototype-1.6.1.js"></script> </head> <body> <div id="container"> <div id="content"> <div id="header"> <div class="rollover-home"> <a href="/" class="rollover-home" title="DNA from the Beginning Home"><span class="displace">Home</span></a> </div> </div>  <div id="content-container"> <h1><span> Concept 13</span> Mendelian laws apply to human beings.</h1> <div id="nav"> <ul> <li class="menu1"><a href="index.html" title="CONCEPT" ><span class="displace">CONCEPT</span></a></li> <li class="menu2"><a href="animation.html" title="ANIMATION"><span class="displace">ANIMATION</span></a></li> <li class="menu3"><a href="gallery.html" title="GALLERY"><span class="displace">GALLERY</span></a></li> <li class="menu4"><a href="av.html" title="VIDEO"><span class="displace">VIDEO</span></a></li> <li class="menu5"><a href="bio.html" title="BIO"><span class="displace">BIO</span></a></li> <li class="menu6"><a href="problem.html" title="PROBLEM"><span class="displace">PROBLEM</span></a></li> <li class="menu7"><a href="links.html" title="LINKS" ><span class="displace">LINKS</span></a></li> </ul> <br class="clearfloat" /> </div> <div id="concept"> <img src="/images/13/concept13.jpg" class="concept-image" alt="Mendelian laws apply to human beings." /> <p>Although Mendel's laws were first tested in pea plants and fruit flies, evidence quickly mounted that they applied to all living things. Just as mutations had provided keys to understanding fruit fly genetics, pedigrees of families affected by diseases provided many of the first examples of Mendelian inheritance in humans.<p> <p>Recessive inheritance was first described for the disorders alkaptonuria (1902) and albinism (1903). Among the first dominant disorders discovered were brachydactyly (short fingers, 1905), congenital cataracts (1906), and Huntington's chorea (1913). Duchenne muscular dystrophy (1913), red-green color blindness (1914), and hemophilia (1916) were the first sex-linked disorders. The simple concept of eye color inheritance — brown is dominant, blue is recessive — was published in 1907; however, scientists now believe that several genes are involved.</p> </div> </div> <br class="clearfloat" /> <div id="footer"> <ul> <li><a href="/">Home</a></li> <li><a href="/sitemap.html">Site Map</a></li> <li><a href="/scientists.html">Scientists</a></li> <li><a href="/glossary.html">Glossary</a></li> <li><a href="/feedback.html">Feedback</a></li> <li><a href="/awards.html">Awards</a></li> <li><a href="/credits.html">Credits</a></li> <li><a href="http://blogs.dnalc.org/dnaftb/" style="background-image:none;">Blog</a></li> </ul> <p> Funded by <a href="http://macyfoundation.org">The Josiah Macy, Jr. Foundation</a><br /> © 2002 - 2011, <a href="http://www.dnalc.org/"> DNA Learning Center</a>, <a href="https://www.cshl.edu/">Cold Spring Harbor Laboratory</a>. All rights reserved. </p> </div>  </div> <div id="sidebar"> <div id="search" > <form method="get" action="/search"> <div class="fieldHolder1"> <input type="search" id="q" name="q" placeholder="Search" onclick="this.value=''" value="" /> <img style="background-color:#9C0;" src="/images/general/search_icon.jpg" alt="Search" onclick="document.forms[0].submit()" /> </div> </form> </div>  <div id="sidebar"> <ul class="sections-side sections-side1a" style="padding-top: 56px; margin-top: 3px;"> <li ><a href="/1/"><img src="/images/thumbnails/1-thumb-sm.png" alt="1." />Children resemble their parents.</a></li> <li ><a href="/2/"><img src="/images/thumbnails/2-thumb-sm.png" alt="2." />Genes come in pairs.</a></li> <li ><a href="/3/"><img src="/images/thumbnails/3-thumb-sm.png" alt="3." />Genes don't blend.</a></li> <li ><a href="/4/"><img src="/images/thumbnails/4-thumb-sm.png" alt="4." />Some genes are dominant.</a></li> <li ><a href="/5/"><img src="/images/thumbnails/5-thumb-sm.png" alt="5." />Genetic inheritance follows rules.</a></li> <li ><a href="/6/"><img src="/images/thumbnails/6-thumb-sm.png" alt="6." />Genes are real things.</a></li> <li ><a href="/7/"><img src="/images/thumbnails/7-thumb-sm.png" alt="7." />All cells arise from pre-existing cells.</a></li> <li ><a href="/8/"><img src="/images/thumbnails/8-thumb-sm.png" alt="8." />Sex cells have one set of chromosomes; body cells have two.</a></li> <li ><a href="/9/"><img src="/images/thumbnails/9-thumb-sm.png" alt="9." />Specialized chromosomes determine sex.</a></li> <li ><a href="/10/"><img src="/images/thumbnails/10-thumb-sm.png" alt="10." />Chromosomes carry genes.</a></li> <li ><a href="/11/"><img src="/images/thumbnails/11-thumb-sm.png" alt="11." />Genes get shuffled when chromosomes exchange pieces.</a></li> <li ><a href="/12/"><img src="/images/thumbnails/12-thumb-sm.png" alt="12." />Evolution begins with the inheritance of gene variations.</a></li> <li ><a class="concept-highlight" href="/13/"><img src="/images/thumbnails/13-thumb-sm.png" alt="13." />Mendelian laws apply to human beings.</a></li> <li style="border-bottom: 1px solid #669;"><a href="/14/"><img src="/images/thumbnails/14-thumb-sm.png" alt="14." />Mendelian genetics cannot fully explain human health and behavior.</a></li> </ul> <ul class="menu-side"> <li class="section2"><a href="/15/index.html" title="Molecules of Genetics"><span class="displace">MOLECULES OF GENETICS</span></a></li> <li class="section3" ><a href="/29/index.html" title="Genetic Organization and Control"><span class="displace">GENETIC ORGANIZATION AND CONTROL</span></a></li> </ul> </div> </div>  <br class="clearfloat" /> </div>  <script type="text/javascript"> Event.observe(window, 'load', function() { var uri = '/13/index.html'; uri = uri.replace(/-\d/,''); $('nav').down().descendants().each(function(s) { if (s.nodeName == 'A') { if (s.href.match(uri)) { s.addClassName('current'); throw $break; } } }); }); </script> <script type="text/javascript"> var _gaq = _gaq || []; _gaq.push(['_setAccount', 'UA-1818773-10']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = 'https://www.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); </script>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-K6EHFCRJBP"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-K6EHFCRJBP'); </script> </body> </html>