CINXE.COM

<!DOCTYPE html> <html lang="en" xmlns:fb="http://www.facebook.com/2008/fbml" class="wf-loading"> <head prefix="og: https://ogp.me/ns# fb: https://ogp.me/ns/fb# academia: https://ogp.me/ns/fb/academia#"> <meta charset="utf-8"> <meta name=viewport content="width=device-width, initial-scale=1"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <title>Vladimir Bumbasirevic - Academia.edu</title>  <link href="//a.academia-assets.com/images/favicons/favicon-production.ico" rel="shortcut icon" type="image/vnd.microsoft.icon"> <link rel="apple-touch-icon" sizes="57x57" href="//a.academia-assets.com/images/favicons/apple-touch-icon-57x57.png"> <link rel="apple-touch-icon" sizes="60x60" href="//a.academia-assets.com/images/favicons/apple-touch-icon-60x60.png"> <link rel="apple-touch-icon" sizes="72x72" href="//a.academia-assets.com/images/favicons/apple-touch-icon-72x72.png"> <link rel="apple-touch-icon" sizes="76x76" href="//a.academia-assets.com/images/favicons/apple-touch-icon-76x76.png"> <link rel="apple-touch-icon" sizes="114x114" href="//a.academia-assets.com/images/favicons/apple-touch-icon-114x114.png"> <link rel="apple-touch-icon" sizes="120x120" href="//a.academia-assets.com/images/favicons/apple-touch-icon-120x120.png"> <link rel="apple-touch-icon" sizes="144x144" href="//a.academia-assets.com/images/favicons/apple-touch-icon-144x144.png"> <link rel="apple-touch-icon" sizes="152x152" href="//a.academia-assets.com/images/favicons/apple-touch-icon-152x152.png"> <link rel="apple-touch-icon" sizes="180x180" href="//a.academia-assets.com/images/favicons/apple-touch-icon-180x180.png"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-194x194.png" sizes="194x194"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-96x96.png" sizes="96x96"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/android-chrome-192x192.png" sizes="192x192"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="manifest" href="//a.academia-assets.com/images/favicons/manifest.json"> <meta name="msapplication-TileColor" content="#2b5797"> <meta name="msapplication-TileImage" content="//a.academia-assets.com/images/favicons/mstile-144x144.png"> <meta name="theme-color" content="#ffffff"> <script> window.performance && window.performance.measure && window.performance.measure("Time To First Byte", "requestStart", "responseStart"); </script> <script> (function() { if (!window.URLSearchParams || !window.history || !window.history.replaceState) { return; } var searchParams = new URLSearchParams(window.location.search); var paramsToDelete = [ 'fs', 'sm', 'swp', 'iid', 'nbs', 'rcc', // related content category 'rcpos', // related content carousel position 'rcpg', // related carousel page 'rchid', // related content hit id 'f_ri', // research interest id, for SEO tracking 'f_fri', // featured research interest, for SEO tracking (param key without value) 'f_rid', // from research interest directory for SEO tracking 'f_loswp', // from research interest pills on LOSWP sidebar for SEO tracking 'rhid', // referrring hit id ]; if (paramsToDelete.every((key) => searchParams.get(key) === null)) { return; } paramsToDelete.forEach((key) => { searchParams.delete(key); }); var cleanUrl = new URL(window.location.href); cleanUrl.search = searchParams.toString(); history.replaceState({}, document.title, cleanUrl); })(); </script> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "profiles/works", 'action': "summary", 'controller_action': 'profiles/works#summary', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script type="text/javascript"> window.sendUserTiming = function(timingName) { if (!(window.performance && window.performance.measure)) return; var entries = window.performance.getEntriesByName(timingName, "measure"); if (entries.length !== 1) return; var timingValue = Math.round(entries[0].duration); gtag('event', 'timing_complete', { name: timingName, value: timingValue, event_category: 'User-centric', }); }; window.sendUserTiming("Time To First Byte"); </script> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="XEj37QlLVWXW5eaImZGigmrCh56GkmvQxhKFJKGbHlCT+NMVbMG8bmO87xoSrrNTrWxTs6cqFZdl3wA+XGfZOA==" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/wow-77f7b87cb1583fc59aa8f94756ebfe913345937eb932042b4077563bebb5fb4b.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/social/home-1c712297ae3ac71207193b1bae0ecf1aae125886850f62c9c0139dd867630797.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/heading-b2b823dd904da60a48fd1bfa1defd840610c2ff414d3f39ed3af46277ab8df3b.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link crossorigin="" href="https://fonts.gstatic.com/" rel="preconnect" /><link href="https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=Gupter:wght@400;500;700&family=IBM+Plex+Mono:wght@300;400&family=Material+Symbols+Outlined:opsz,wght,FILL,GRAD@20,400,0,0&display=swap" rel="stylesheet" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/common-10fa40af19d25203774df2d4a03b9b5771b45109c2304968038e88a81d1215c5.css" /> <meta name="author" content="vladimir bumbasirevic" /> <meta name="description" content="Vladimir Bumbasirevic: 1 Follower, 1 Following, 64 Research papers. Research interests: Greece, Western Balkans, and Kosovo." /> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs" /> <script> var $controller_name = 'works'; var $action_name = "summary"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.Aedu = { hit_data: null }; window.Aedu.SiteStats = {"premium_universities_count":15275,"monthly_visitors":"113 million","monthly_visitor_count":113468711,"monthly_visitor_count_in_millions":113,"user_count":277137725,"paper_count":55203019,"paper_count_in_millions":55,"page_count":432000000,"page_count_in_millions":432,"pdf_count":16500000,"pdf_count_in_millions":16}; window.Aedu.serverRenderTime = new Date(1732392160000); window.Aedu.timeDifference = new Date().getTime() - 1732392160000; window.Aedu.isUsingCssV1 = false; window.Aedu.enableLocalization = true; window.Aedu.activateFullstory = false; window.Aedu.serviceAvailability = { status: {"attention_db":"on","bibliography_db":"on","contacts_db":"on","email_db":"on","indexability_db":"on","mentions_db":"on","news_db":"on","notifications_db":"on","offsite_mentions_db":"on","redshift":"on","redshift_exports_db":"on","related_works_db":"on","ring_db":"on","user_tests_db":"on"}, serviceEnabled: function(service) { return this.status[service] === "on"; }, readEnabled: function(service) { return this.serviceEnabled(service) || this.status[service] === "read_only"; }, }; window.Aedu.viewApmTrace = function() { // Check if x-apm-trace-id meta tag is set, and open the trace in APM // in a new window if it is. var apmTraceId = document.head.querySelector('meta[name="x-apm-trace-id"]'); if (apmTraceId) { var traceId = apmTraceId.content; // Use trace ID to construct URL, an example URL looks like: // https://app.datadoghq.com/apm/traces?query=trace_id%31298410148923562634 var apmUrl = 'https://app.datadoghq.com/apm/traces?query=trace_id%3A' + traceId; window.open(apmUrl, '_blank'); } }; </script>  <link href="https://fonts.googleapis.com/css?family=Roboto:100,100i,300,300i,400,400i,500,500i,700,700i,900,900i" rel="stylesheet"> <link href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css" rel="stylesheet"> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/libraries-a9675dcb01ec4ef6aa807ba772c7a5a00c1820d3ff661c1038a20f80d06bb4e4.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/academia-296162c7af6fd81dcdd76f1a94f1fad04fb5f647401337d136fe8b68742170b1.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system_legacy-056a9113b9a0f5343d013b29ee1929d5a18be35fdcdceb616600b4db8bd20054.css" /> <script src="//a.academia-assets.com/assets/webpack_bundles/runtime-bundle-005434038af4252ca37c527588411a3d6a0eabb5f727fac83f8bbe7fd88d93bb.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/webpack_libraries_and_infrequently_changed.wjs-bundle-8d53a22151f33ab413d88fa1c02f979c3f8706d470fc1bced09852c72a9f3454.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/core_webpack.wjs-bundle-f8fe82512740391f81c9e8cc48220144024b425b359b08194e316f4de070b9e8.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/sentry.wjs-bundle-5fe03fddca915c8ba0f7edbe64c194308e8ce5abaed7bffe1255ff37549c4808.js"></script> <script> jade = window.jade || {}; jade.helpers = window.$h; jade._ = window._; </script>  <script id="tag-manager-head-root">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer_old','GTM-5G9JF7Z');</script>  <script> window.gptadslots = []; window.googletag = window.googletag || {}; window.googletag.cmd = window.googletag.cmd || []; </script> <script type="text/javascript"> // TODO(jacob): This should be defined, may be rare load order problem. // Checking if null is just a quick fix, will default to en if unset. // Better fix is to run this immedietely after I18n is set. if (window.I18n != null) { I18n.defaultLocale = "en"; I18n.locale = "en"; I18n.fallbacks = true; } </script> <link rel="canonical" href="https://independent.academia.edu/VladimirBumbasirevic" /> </head>   <body class='c-profiles/works a-summary logged_out'>  <div id="fb-root"></div><script>window.fbAsyncInit = function() { FB.init({ appId: "2369844204", version: "v8.0", status: true, cookie: true, xfbml: true }); // Additional initialization code. if (window.InitFacebook) { // facebook.ts already loaded, set it up. window.InitFacebook(); } else { // Set a flag for facebook.ts to find when it loads. window.academiaAuthReadyFacebook = true; } };</script><script>window.fbAsyncLoad = function() { // Protection against double calling of this function if (window.FB) { return; } (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) {return;} js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_US/sdk.js"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk')); } if (!window.defer_facebook) { // Autoload if not deferred window.fbAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.fbAsyncLoad(); }, 5000); }</script> <div id="google-root"></div><script>window.loadGoogle = function() { if (window.InitGoogle) { // google.ts already loaded, set it up. window.InitGoogle("331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"); } else { // Set a flag for google.ts to use when it loads. window.GoogleClientID = "331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"; } };</script><script>window.googleAsyncLoad = function() { // Protection against double calling of this function (function(d) { var js; var id = 'google-jssdk'; var ref = d.getElementsByTagName('script')[0]; if (d.getElementById(id)) { return; } js = d.createElement('script'); js.id = id; js.async = true; js.onload = loadGoogle; js.src = "https://accounts.google.com/gsi/client" ref.parentNode.insertBefore(js, ref); }(document)); } if (!window.defer_google) { // Autoload if not deferred window.googleAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.googleAsyncLoad(); }, 5000); }</script> <div id="tag-manager-body-root">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5G9JF7Z" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>   <script> window.addEventListener('load', function() { if (document.querySelector('input[name="commit"]')) { document.querySelector('input[name="commit"]').addEventListener('click', function() { gtag('event', 'click', { event_category: 'button', event_label: 'Log In' }) }) } }); </script> </div> <script>var _comscore = _comscore || []; _comscore.push({ c1: "2", c2: "26766707" }); (function() { var s = document.createElement("script"), el = document.getElementsByTagName("script")[0]; s.async = true; s.src = (document.location.protocol == "https:" ? "https://sb" : "http://b") + ".scorecardresearch.com/beacon.js"; el.parentNode.insertBefore(s, el); })();</script><img src="https://sb.scorecardresearch.com/p?c1=2&c2=26766707&cv=2.0&cj=1" style="position: absolute; visibility: hidden" /> <div id='react-modal'></div> <div class='DesignSystem'> <a class='u-showOnFocus' href='#site'> Skip to main content </a> </div> <div id="upgrade_ie_banner" style="display: none;"><p>Academia.edu no longer supports Internet Explorer.</p><p>To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to <a href="https://www.academia.edu/upgrade-browser">upgrade your browser</a>.</p></div><script>// Show this banner for all versions of IE if (!!window.MSInputMethodContext || /(MSIE)/.test(navigator.userAgent)) { document.getElementById('upgrade_ie_banner').style.display = 'block'; }</script> <div class="DesignSystem bootstrap ShrinkableNav"><div class="navbar navbar-default main-header"><div class="container-wrapper" id="main-header-container"><div class="container"><div class="navbar-header"><div class="nav-left-wrapper u-mt0x"><div class="nav-logo"><a data-main-header-link-target="logo_home" href="https://www.academia.edu/"><img class="visible-xs-inline-block" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015-A.svg" width="24" height="24" /><img width="145.2" height="18" class="hidden-xs" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015.svg" /></a></div><div class="nav-search"><div class="SiteSearch-wrapper select2-no-default-pills"><form class="js-SiteSearch-form DesignSystem" action="https://www.academia.edu/search" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><i class="SiteSearch-icon fa fa-search u-fw700 u-positionAbsolute u-tcGrayDark"></i><input class="js-SiteSearch-form-input SiteSearch-form-input form-control" data-main-header-click-target="search_input" name="q" placeholder="Search" type="text" value="" /></form></div></div></div><div class="nav-right-wrapper pull-right"><ul class="NavLinks js-main-nav list-unstyled"><li class="NavLinks-link"><a class="js-header-login-url Button Button--inverseGray Button--sm u-mb4x" id="nav_log_in" rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="NavLinks-link u-p0x"><a class="Button Button--inverseGray Button--sm u-mb4x" rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li></ul><button class="hidden-lg hidden-md hidden-sm u-ml4x navbar-toggle collapsed" data-target=".js-mobile-header-links" data-toggle="collapse" type="button"><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span></button></div></div><div class="collapse navbar-collapse js-mobile-header-links"><ul class="nav navbar-nav"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li><li class="u-borderColorGrayLight u-borderBottom1 js-mobile-nav-expand-trigger"><a href="#">more&nbsp<span class="caret"></span></a></li><li><ul class="js-mobile-nav-expand-section nav navbar-nav u-m0x collapse"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/about">About</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/press">Press</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://medium.com/@academia">Blog</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/documents">Papers</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/hiring"><i class="fa fa-briefcase"></i> We're Hiring!</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://support.academia.edu/"><i class="fa fa-question-circle"></i> Help Center</a></li><li class="js-mobile-nav-collapse-trigger u-borderColorGrayLight u-borderBottom1 dropup" style="display:none"><a href="#">less&nbsp<span class="caret"></span></a></li></ul></li></ul></div></div></div><script>(function(){ var $moreLink = $(".js-mobile-nav-expand-trigger"); var $lessLink = $(".js-mobile-nav-collapse-trigger"); var $section = $('.js-mobile-nav-expand-section'); $moreLink.click(function(ev){ ev.preventDefault(); $moreLink.hide(); $lessLink.show(); $section.collapse('show'); }); $lessLink.click(function(ev){ ev.preventDefault(); $moreLink.show(); $lessLink.hide(); $section.collapse('hide'); }); })() if ($a.is_logged_in() || false) { new Aedu.NavigationController({ el: '.js-main-nav', showHighlightedNotification: false }); } else { $(".js-header-login-url").attr("href", $a.loginUrlWithRedirect()); } Aedu.autocompleteSearch = new AutocompleteSearch({el: '.js-SiteSearch-form'});</script></div></div> <div id='site' class='fixed'> <div id="content" class="clearfix"> <script>document.addEventListener('DOMContentLoaded', function(){ var $dismissible = $(".dismissible_banner"); $dismissible.click(function(ev) { $dismissible.hide(); }); });</script> <script src="//a.academia-assets.com/assets/webpack_bundles/profile.wjs-bundle-9601d1cc3d68aa07c0a9901d03d3611aec04cc07d2a2039718ebef4ad4d148ca.js" defer="defer"></script><script>Aedu.rankings = { showPaperRankingsLink: false } $viewedUser = Aedu.User.set_viewed( {"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic","photo":"/images/s65_no_pic.png","has_photo":false,"is_analytics_public":false,"interests":[{"id":48044,"name":"Greece","url":"https://www.academia.edu/Documents/in/Greece"},{"id":89536,"name":"Western Balkans","url":"https://www.academia.edu/Documents/in/Western_Balkans"},{"id":5839,"name":"Kosovo","url":"https://www.academia.edu/Documents/in/Kosovo"},{"id":5993,"name":"Bosnia","url":"https://www.academia.edu/Documents/in/Bosnia"},{"id":77031,"name":"Macedonia","url":"https://www.academia.edu/Documents/in/Macedonia"}]} ); if ($a.is_logged_in() && $viewedUser.is_current_user()) { $('body').addClass('profile-viewed-by-owner'); } $socialProfiles = []</script><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/VladimirBumbasirevic","location":"/VladimirBumbasirevic","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/VladimirBumbasirevic","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="ProfileCheckPaperUpdate" data-props="{}" data-trace="false" data-dom-id="ProfileCheckPaperUpdate-react-component-2304298a-9801-40b8-99e9-96885a13faa8"></div> <div id="ProfileCheckPaperUpdate-react-component-2304298a-9801-40b8-99e9-96885a13faa8"></div> <div class="DesignSystem"><div class="onsite-ping" id="onsite-ping"></div></div><div class="profile-user-info DesignSystem"><div class="social-profile-container"><div class="left-panel-container"><div class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Vladimir Bumbasirevic</h1><div class="affiliations-container fake-truncate js-profile-affiliations"></div></div></div><div class="sidebar-cta-container"><button class="ds2-5-button hidden profile-cta-button grow js-profile-follow-button" data-broccoli-component="user-info.follow-button" data-click-track="profile-user-info-follow-button" data-follow-user-fname="Vladimir" data-follow-user-id="15465688" data-follow-user-source="profile_button" data-has-google="false"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">add</span>Follow</button><button class="ds2-5-button hidden profile-cta-button grow js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" data-click-track="profile-user-info-unfollow-button" data-unfollow-user-id="15465688"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">done</span>Following</button></div></div><div class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Follower</p><p class="data">1</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">1</p></div></a><a href="/VladimirBumbasirevic/mentions"><div class="stat-container"><p class="label">Mentions</p><p class="data">1</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15465688" href="https://www.academia.edu/Documents/in/Greece"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/VladimirBumbasirevic","location":"/VladimirBumbasirevic","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/VladimirBumbasirevic","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Greece"]}" data-trace="false" data-dom-id="Pill-react-component-8f47413c-e3cb-4cc2-b982-ca120f58e58c"></div> <div id="Pill-react-component-8f47413c-e3cb-4cc2-b982-ca120f58e58c"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15465688" href="https://www.academia.edu/Documents/in/Western_Balkans"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Western Balkans"]}" data-trace="false" data-dom-id="Pill-react-component-946833e0-964d-47d7-b3aa-4995bb648b2e"></div> <div id="Pill-react-component-946833e0-964d-47d7-b3aa-4995bb648b2e"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15465688" href="https://www.academia.edu/Documents/in/Kosovo"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Kosovo"]}" data-trace="false" data-dom-id="Pill-react-component-35153e77-083a-4fcc-b944-ca168acf6041"></div> <div id="Pill-react-component-35153e77-083a-4fcc-b944-ca168acf6041"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15465688" href="https://www.academia.edu/Documents/in/Bosnia"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Bosnia"]}" data-trace="false" data-dom-id="Pill-react-component-f4cf4d5c-f131-45ff-8672-3e7a44cc9b20"></div> <div id="Pill-react-component-f4cf4d5c-f131-45ff-8672-3e7a44cc9b20"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15465688" href="https://www.academia.edu/Documents/in/Macedonia"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Macedonia"]}" data-trace="false" data-dom-id="Pill-react-component-5f2c4865-dac6-4a11-892e-d5d7075ddb08"></div> <div id="Pill-react-component-5f2c4865-dac6-4a11-892e-d5d7075ddb08"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Vladimir Bumbasirevic</h3></div><div class="js-work-strip profile--work_container" data-work-id="110530399"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome"><img alt="Research paper thumbnail of Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome">Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome</a></div><div class="wp-workCard_item"><span>Forensic Science Medicine and Pathology</span><span>, Feb 21, 2023</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530399"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530399"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530399; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530399]").text(description); $(".js-view-count[data-work-id=110530399]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530399; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530399']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530399, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530399]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530399,"title":"Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome","translated_title":"","metadata":{"publisher":"Springer Science+Business Media","publication_date":{"day":21,"month":2,"year":2023,"errors":{}},"publication_name":"Forensic Science Medicine and Pathology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome","translated_internal_url":"","created_at":"2023-12-04T04:17:04.681-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":165,"name":"Pathology","url":"https://www.academia.edu/Documents/in/Pathology"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":197297,"name":"Lung","url":"https://www.academia.edu/Documents/in/Lung"},{"id":314484,"name":"Autopsy","url":"https://www.academia.edu/Documents/in/Autopsy"},{"id":463111,"name":"Ards","url":"https://www.academia.edu/Documents/in/Ards"}],"urls":[{"id":36415062,"url":"https://doi.org/10.1007/s12024-022-00572-4"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530395"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS"><img alt="Research paper thumbnail of INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS">INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS</a></div><div class="wp-workCard_item"><span>Biochemical Society Transactions</span><span>, Nov 1, 1996</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530395"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530395"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530395; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530395]").text(description); $(".js-view-count[data-work-id=110530395]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530395; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530395']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530395, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530395]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530395,"title":"INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS","translated_title":"","metadata":{"publisher":"Portland Press","publication_date":{"day":1,"month":11,"year":1996,"errors":{}},"publication_name":"Biochemical Society Transactions"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS","translated_internal_url":"","created_at":"2023-12-04T04:17:01.494-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"}],"urls":[{"id":36415058,"url":"https://doi.org/10.1042/bst024612sa"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530394"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_"><img alt="Research paper thumbnail of [Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_">[Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, 1980</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530394"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530394"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530394; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530394]").text(description); $(".js-view-count[data-work-id=110530394]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530394; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530394']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530394, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530394]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530394,"title":"[Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1980,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_","translated_internal_url":"","created_at":"2023-12-04T04:17:01.003-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":55608,"name":"Ontogeny","url":"https://www.academia.edu/Documents/in/Ontogeny"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":86150,"name":"Touch","url":"https://www.academia.edu/Documents/in/Touch"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":128559,"name":"Mechanoreceptors","url":"https://www.academia.edu/Documents/in/Mechanoreceptors"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":1028516,"name":"Fingers","url":"https://www.academia.edu/Documents/in/Fingers"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"},{"id":3763168,"name":"Index Finger","url":"https://www.academia.edu/Documents/in/Index_Finger"}],"urls":[{"id":36415057,"url":"https://pubmed.ncbi.nlm.nih.gov/7233262"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530393"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_"><img alt="Research paper thumbnail of [Morphology and function of the neglected ligament of the foot]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_">[Morphology and function of the neglected ligament of the foot]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Apr 1, 1984</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530393"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530393"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530393; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530393]").text(description); $(".js-view-count[data-work-id=110530393]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530393; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530393']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530393, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530393]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530393,"title":"[Morphology and function of the neglected ligament of the foot]","translated_title":"","metadata":{"publication_date":{"day":1,"month":4,"year":1984,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_","translated_internal_url":"","created_at":"2023-12-04T04:17:00.587-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Morphology_and_function_of_the_neglected_ligament_of_the_foot_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":24554,"name":"Ligament","url":"https://www.academia.edu/Documents/in/Ligament"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":449523,"name":"Foot","url":"https://www.academia.edu/Documents/in/Foot"},{"id":990519,"name":"Ligaments","url":"https://www.academia.edu/Documents/in/Ligaments"}],"urls":[{"id":36415056,"url":"https://pubmed.ncbi.nlm.nih.gov/6515479"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530391"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_"><img alt="Research paper thumbnail of [Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_">[Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Feb 1, 1980</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530391"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530391"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530391; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530391]").text(description); $(".js-view-count[data-work-id=110530391]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530391; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530391']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530391, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530391]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530391,"title":"[Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]","translated_title":"","metadata":{"publication_date":{"day":1,"month":2,"year":1980,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_","translated_internal_url":"","created_at":"2023-12-04T04:17:00.086-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":86150,"name":"Touch","url":"https://www.academia.edu/Documents/in/Touch"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":128559,"name":"Mechanoreceptors","url":"https://www.academia.edu/Documents/in/Mechanoreceptors"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":500368,"name":"Hand","url":"https://www.academia.edu/Documents/in/Hand"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"}],"urls":[{"id":36415054,"url":"https://pubmed.ncbi.nlm.nih.gov/7244858"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530389"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro"><img alt="Research paper thumbnail of Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro" class="work-thumbnail" src="https://attachments.academia-assets.com/108319828/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro">Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Jun 1, 1995</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d909bf8b39dd294f1dc497e711d0c292" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319828,"asset_id":110530389,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530389"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530389"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530389; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530389]").text(description); $(".js-view-count[data-work-id=110530389]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530389; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530389']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530389, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "d909bf8b39dd294f1dc497e711d0c292" } } $('.js-work-strip[data-work-id=110530389]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530389,"title":"Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro","translated_title":"","metadata":{"abstract":"Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.","publication_date":{"day":1,"month":6,"year":1995,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.","internal_url":"https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro","translated_internal_url":"","created_at":"2023-12-04T04:16:59.595-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319828/thumbnails/1.jpg","file_name":"359176980.pdf","download_url":"https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_induced_by_microtubule_disrupt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319828/359176980-libre.pdf?1701696019=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_induced_by_microtubule_disrupt.pdf\u0026Expires=1732395759\u0026Signature=DcEauM9bCj1sZeB57yEF~UvcxzPCb3cRXQWXGqpBMJ77QqwKLfMrnW~ZSe~3uJoJwyEEBQrBtVMM3YW-kttpV0iVg-DMYNIHZxkaurC8ehFpvdliGoJMzNquGBoDStFwACcA-B1d1-0w6df15mmRwtqwDpWWK9aLPbg3ox1XN13EZFNuBMB~CYlziNYB7bpMlJCuueTSXOY2KtiwucunmZSLbSR5wIXtUqYkM9af5e7LvxfgasKBKvKJ2bkjyXE0logif3Tc3PenGCIJ3yXGeAnUVjljkbQR1~2ls4nvpWbdWCLQpMHsmT~KVGNNojRRGa50BZUm-bMFHc0xVzjtGw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319828/thumbnails/1.jpg","file_name":"359176980.pdf","download_url":"https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_induced_by_microtubule_disrupt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319828/359176980-libre.pdf?1701696019=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_induced_by_microtubule_disrupt.pdf\u0026Expires=1732395759\u0026Signature=DcEauM9bCj1sZeB57yEF~UvcxzPCb3cRXQWXGqpBMJ77QqwKLfMrnW~ZSe~3uJoJwyEEBQrBtVMM3YW-kttpV0iVg-DMYNIHZxkaurC8ehFpvdliGoJMzNquGBoDStFwACcA-B1d1-0w6df15mmRwtqwDpWWK9aLPbg3ox1XN13EZFNuBMB~CYlziNYB7bpMlJCuueTSXOY2KtiwucunmZSLbSR5wIXtUqYkM9af5e7LvxfgasKBKvKJ2bkjyXE0logif3Tc3PenGCIJ3yXGeAnUVjljkbQR1~2ls4nvpWbdWCLQpMHsmT~KVGNNojRRGa50BZUm-bMFHc0xVzjtGw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":10655,"name":"Scanning Electron Microscopy","url":"https://www.academia.edu/Documents/in/Scanning_Electron_Microscopy"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":55267,"name":"Mitosis","url":"https://www.academia.edu/Documents/in/Mitosis"},{"id":84910,"name":"Mouse","url":"https://www.academia.edu/Documents/in/Mouse"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":172350,"name":"Microtubules","url":"https://www.academia.edu/Documents/in/Microtubules"},{"id":175490,"name":"Programmed cell death","url":"https://www.academia.edu/Documents/in/Programmed_cell_death"},{"id":371370,"name":"Colchicine","url":"https://www.academia.edu/Documents/in/Colchicine"},{"id":1166930,"name":"Cytoplasm","url":"https://www.academia.edu/Documents/in/Cytoplasm"},{"id":1168109,"name":"Mitotic Index","url":"https://www.academia.edu/Documents/in/Mitotic_Index"},{"id":1959383,"name":"Interphase","url":"https://www.academia.edu/Documents/in/Interphase"},{"id":2256666,"name":"DNA fragmentation","url":"https://www.academia.edu/Documents/in/DNA_fragmentation"},{"id":3120495,"name":"Thymocytes","url":"https://www.academia.edu/Documents/in/Thymocytes"}],"urls":[{"id":36415052,"url":"https://pubmed.ncbi.nlm.nih.gov/8714746"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530385"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1"><img alt="Research paper thumbnail of Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1" class="work-thumbnail" src="https://attachments.academia-assets.com/108319846/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1">Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1</a></div><div class="wp-workCard_item"><span>Psychopharmacology</span><span>, Feb 5, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8116ee6a5830a8b819b2bddbce53ec16" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319846,"asset_id":110530385,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530385"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530385"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530385; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530385]").text(description); $(".js-view-count[data-work-id=110530385]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530385; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530385']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530385, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8116ee6a5830a8b819b2bddbce53ec16" } } $('.js-work-strip[data-work-id=110530385]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530385,"title":"Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1","translated_title":"","metadata":{"publisher":"Springer Science+Business Media","publication_date":{"day":5,"month":2,"year":2013,"errors":{}},"publication_name":"Psychopharmacology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1","translated_internal_url":"","created_at":"2023-12-04T04:16:57.791-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319846,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319846/thumbnails/1.jpg","file_name":"s00213-013-2999-720231204-1-6xyz46.pdf","download_url":"https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Perinatal_phencyclidine_administration_d.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319846/s00213-013-2999-720231204-1-6xyz46-libre.pdf?1701696002=\u0026response-content-disposition=attachment%3B+filename%3DPerinatal_phencyclidine_administration_d.pdf\u0026Expires=1732395759\u0026Signature=Rapn1kXe8o7YlZ-MLoLgQZ6WTNX3z~IoXUlydcFc88mMIQ9vbB3iYlvGiXaBZLPsH0WD6czBWXrugSu~mTHCw1rX4CTCPaczLO0Zf8OhfnKuNzzlIDsF0E7RmiCfqajtm~Vu4GLDBbEt4yfE1Fx9Em46U6Z2EBl~n90UAfJrhzr4oBwfkwTj~dqZAeyj9Ulvwaiky7mk4B-JJra6fn33hVII6~dJhthd2LP6tt0OKXlclqtvyJHqxxLQVDpEBkAKHjUwnz1UeQ8MCd9bmW7tcBpf9Asq6UghGQ5kgiUHlke~vRM2qOixhnhd9J-oEmrlkBwqL8c-BUT8lGLASLeQeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319846,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319846/thumbnails/1.jpg","file_name":"s00213-013-2999-720231204-1-6xyz46.pdf","download_url":"https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Perinatal_phencyclidine_administration_d.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319846/s00213-013-2999-720231204-1-6xyz46-libre.pdf?1701696002=\u0026response-content-disposition=attachment%3B+filename%3DPerinatal_phencyclidine_administration_d.pdf\u0026Expires=1732395759\u0026Signature=Rapn1kXe8o7YlZ-MLoLgQZ6WTNX3z~IoXUlydcFc88mMIQ9vbB3iYlvGiXaBZLPsH0WD6czBWXrugSu~mTHCw1rX4CTCPaczLO0Zf8OhfnKuNzzlIDsF0E7RmiCfqajtm~Vu4GLDBbEt4yfE1Fx9Em46U6Z2EBl~n90UAfJrhzr4oBwfkwTj~dqZAeyj9Ulvwaiky7mk4B-JJra6fn33hVII6~dJhthd2LP6tt0OKXlclqtvyJHqxxLQVDpEBkAKHjUwnz1UeQ8MCd9bmW7tcBpf9Asq6UghGQ5kgiUHlke~vRM2qOixhnhd9J-oEmrlkBwqL8c-BUT8lGLASLeQeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience"},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":2047,"name":"Psychopharmacology","url":"https://www.academia.edu/Documents/in/Psychopharmacology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":35881,"name":"Interneuron","url":"https://www.academia.edu/Documents/in/Interneuron"},{"id":57556,"name":"Hippocampus","url":"https://www.academia.edu/Documents/in/Hippocampus"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":246876,"name":"Dentate Gyrus","url":"https://www.academia.edu/Documents/in/Dentate_Gyrus"},{"id":251026,"name":"Phencyclidine","url":"https://www.academia.edu/Documents/in/Phencyclidine"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":1147511,"name":"Reelin","url":"https://www.academia.edu/Documents/in/Reelin"},{"id":1287048,"name":"Interneurons","url":"https://www.academia.edu/Documents/in/Interneurons"},{"id":1763968,"name":"Gene Expression Regulation","url":"https://www.academia.edu/Documents/in/Gene_Expression_Regulation"},{"id":2226469,"name":"Hippocampal formation","url":"https://www.academia.edu/Documents/in/Hippocampal_formation"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[{"id":36415049,"url":"https://doi.org/10.1007/s00213-013-2999-7"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530383"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma"><img alt="Research paper thumbnail of Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma" class="work-thumbnail" src="https://attachments.academia-assets.com/108319762/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma">Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma</a></div><div class="wp-workCard_item"><span>Oncology Research and Treatment</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies ba...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) &gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="18201f61cb01ef2842afa8dcc1e7074b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319762,"asset_id":110530383,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530383"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530383"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530383; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530383]").text(description); $(".js-view-count[data-work-id=110530383]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530383; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530383']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530383, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "18201f61cb01ef2842afa8dcc1e7074b" } } $('.js-work-strip[data-work-id=110530383]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530383,"title":"Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma","translated_title":"","metadata":{"abstract":"Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) \u0026gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Oncology Research and Treatment"},"translated_abstract":"Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) \u0026gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...","internal_url":"https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma","translated_internal_url":"","created_at":"2023-12-04T04:16:56.694-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319762,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319762/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319762/343664-libre.pdf?1701696018=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=JeSfGqDWmvQtPgBpRcLvng5f7h2NH3tgnuwvcSefUBz2U5QX69GuTT9kMG~D8qf1fuLmjZlKw6Qv0nwwEHxkUV2rFAlCgkBlzhDdxjDZx~tjo02qtwPnISpAdwlDdphJisDZwo~qJ~uxQxGT1vo5dANYG7DjmPQxS4Uk-keO6EBFe7r5FZTTdrhDWLe-TsLmjVFn2YldHHd3vMgXjHKoHuXWGx3xQeIRtxvzxPalsFBHC0pCcEaVeRwT2uvtlIMN-zlPtqQPjE-8cwSL6PrpGfD-aS1H2dp-wp3BnYzG4R-XPtNRSQuleAJw9tolFp5M-5IajJG8BV1shSM4gc7wlA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319762,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319762/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319762/343664-libre.pdf?1701696018=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=JeSfGqDWmvQtPgBpRcLvng5f7h2NH3tgnuwvcSefUBz2U5QX69GuTT9kMG~D8qf1fuLmjZlKw6Qv0nwwEHxkUV2rFAlCgkBlzhDdxjDZx~tjo02qtwPnISpAdwlDdphJisDZwo~qJ~uxQxGT1vo5dANYG7DjmPQxS4Uk-keO6EBFe7r5FZTTdrhDWLe-TsLmjVFn2YldHHd3vMgXjHKoHuXWGx3xQeIRtxvzxPalsFBHC0pCcEaVeRwT2uvtlIMN-zlPtqQPjE-8cwSL6PrpGfD-aS1H2dp-wp3BnYzG4R-XPtNRSQuleAJw9tolFp5M-5IajJG8BV1shSM4gc7wlA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":108319763,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319763/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319763/download_file","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319763/343664-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=gYXySWlvGW6mS-CKPz9Y1blmCLSR40N7N2R163L~AT9-UdkmY-ka0g7aTg-WzlNxSuaCMazwCmg~RianOgCunWSYARYQbUViN0pH~So3WSi2tpX4GOYw2oTfIt-~0da7Q8R92bfBBNOC1IRZkI3BHDloJnU0dTlQ021EkbcQ7GPZFrZTImCr6iNRWnWE-hTaZjqgDFBpnSFiEx-jxv4IFiqr5v6XEdB1rZ7Pp6PFJW4efobDt32Mk91~W1ZihfBKMIub1SlL4Sx5uFkYOzoIZG2KX3fUGNZtQzMPL-rcoH9SfAHbcUn9irzmlvxLmYk9bdyE6BefgjNdykluQqwn7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology"},{"id":17491,"name":"Macrophages","url":"https://www.academia.edu/Documents/in/Macrophages"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28973,"name":"Comorbidity","url":"https://www.academia.edu/Documents/in/Comorbidity"},{"id":55269,"name":"Lymphoma","url":"https://www.academia.edu/Documents/in/Lymphoma"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":216943,"name":"CD","url":"https://www.academia.edu/Documents/in/CD"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":911025,"name":"Lymph Node","url":"https://www.academia.edu/Documents/in/Lymph_Node"},{"id":1187753,"name":"Onkologie","url":"https://www.academia.edu/Documents/in/Onkologie"},{"id":1350756,"name":"Hodgkin disease","url":"https://www.academia.edu/Documents/in/Hodgkin_disease"},{"id":2718075,"name":"lymphangitis","url":"https://www.academia.edu/Documents/in/lymphangitis"}],"urls":[{"id":36415047,"url":"https://www.karger.com/Article/Pdf/343664"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530381"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma"><img alt="Research paper thumbnail of The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma">The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma</a></div><div class="wp-workCard_item"><span>Leukemia &amp; Lymphoma</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable progno...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530381"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530381"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530381; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530381]").text(description); $(".js-view-count[data-work-id=110530381]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530381; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530381']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530381, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530381]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530381,"title":"The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma","translated_title":"","metadata":{"abstract":"Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.","publisher":"Informa UK Limited","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Leukemia \u0026amp; Lymphoma"},"translated_abstract":"Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.","internal_url":"https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma","translated_internal_url":"","created_at":"2023-12-04T04:16:55.708-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology"},{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia"},{"id":17491,"name":"Macrophages","url":"https://www.academia.edu/Documents/in/Macrophages"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":418283,"name":"Proportional hazards model","url":"https://www.academia.edu/Documents/in/Proportional_hazards_model"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis"},{"id":1350756,"name":"Hodgkin disease","url":"https://www.academia.edu/Documents/in/Hodgkin_disease"},{"id":3953591,"name":"ABVD","url":"https://www.academia.edu/Documents/in/ABVD"}],"urls":[{"id":36415045,"url":"http://www.tandfonline.com/doi/pdf/10.3109/10428194.2011.580026"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530379"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant"><img alt="Research paper thumbnail of Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant" class="work-thumbnail" src="https://attachments.academia-assets.com/108319761/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant">Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant</a></div><div class="wp-workCard_item"><span>Clinical and Experimental Immunology</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9bd70c54dc9b97d9e1cfdce71cbee0e6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319761,"asset_id":110530379,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530379"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530379"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530379; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530379]").text(description); $(".js-view-count[data-work-id=110530379]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530379; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530379']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530379, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9bd70c54dc9b97d9e1cfdce71cbee0e6" } } $('.js-work-strip[data-work-id=110530379]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530379,"title":"Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant","translated_title":"","metadata":{"abstract":"SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...","publisher":"Oxford University Press (OUP)","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Clinical and Experimental Immunology"},"translated_abstract":"SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...","internal_url":"https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant","translated_internal_url":"","created_at":"2023-12-04T04:16:55.085-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319761,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319761/thumbnails/1.jpg","file_name":"j.1365-2249.2004.02418.x.pdf","download_url":"https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Induction_of_experimental_autoimmune_enc.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319761/j.1365-2249.2004.02418.x-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DInduction_of_experimental_autoimmune_enc.pdf\u0026Expires=1732395759\u0026Signature=H9rv5GO~IIUbWbUqdWzr07mXragHUJti0remnvad3a6n6ietmDipgLo4VAhxNeN7QgcIDRxb7Nh7tU30MIc0vs0FdTuU~EYx14tunNvx-vgBhDFmN3mTOn8cvmQvxzdda4Er5Bs72Gma4vDks-vJiJDh-t~BQH0t7Gf6kI~NZXyipFYwnUdjMjh1WSi499sFhp3uONIZ5YMNNc~bq2~MiFAaFVD5Is6KP4TYP1Lxho6C80WfFn59T41OghmSRnfu1bV6wxepN9SIca4sHuEs3C3GuJsW0BngRUSawdgLbMr5dAULMijICpRVswSMlf3m71LonS3mUFhEl1E551L89Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319761,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319761/thumbnails/1.jpg","file_name":"j.1365-2249.2004.02418.x.pdf","download_url":"https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Induction_of_experimental_autoimmune_enc.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319761/j.1365-2249.2004.02418.x-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DInduction_of_experimental_autoimmune_enc.pdf\u0026Expires=1732395759\u0026Signature=H9rv5GO~IIUbWbUqdWzr07mXragHUJti0remnvad3a6n6ietmDipgLo4VAhxNeN7QgcIDRxb7Nh7tU30MIc0vs0FdTuU~EYx14tunNvx-vgBhDFmN3mTOn8cvmQvxzdda4Er5Bs72Gma4vDks-vJiJDh-t~BQH0t7Gf6kI~NZXyipFYwnUdjMjh1WSi499sFhp3uONIZ5YMNNc~bq2~MiFAaFVD5Is6KP4TYP1Lxho6C80WfFn59T41OghmSRnfu1bV6wxepN9SIca4sHuEs3C3GuJsW0BngRUSawdgLbMr5dAULMijICpRVswSMlf3m71LonS3mUFhEl1E551L89Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis"},{"id":12320,"name":"Autoimmunity","url":"https://www.academia.edu/Documents/in/Autoimmunity"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":66613,"name":"Autoimmune Disease","url":"https://www.academia.edu/Documents/in/Autoimmune_Disease"},{"id":99421,"name":"Spinal Cord","url":"https://www.academia.edu/Documents/in/Spinal_Cord"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System"},{"id":989400,"name":"Experimental Autoimmune Encephalomyelitis","url":"https://www.academia.edu/Documents/in/Experimental_Autoimmune_Encephalomyelitis"},{"id":1425672,"name":"Encephalomyelitis","url":"https://www.academia.edu/Documents/in/Encephalomyelitis"},{"id":1485245,"name":"Adjuvant","url":"https://www.academia.edu/Documents/in/Adjuvant"}],"urls":[{"id":36415044,"url":"https://academic.oup.com/cei/article-pdf/136/1/49/42145853/j.1365-2249.2004.02418.x.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530296"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons"><img alt="Research paper thumbnail of Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons" class="work-thumbnail" src="https://attachments.academia-assets.com/108319749/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons">Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons</a></div><div class="wp-workCard_item"><span>Acta veterinaria</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="05495a34eb9b648a08ad7eaf7854e8d8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319749,"asset_id":110530296,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530296"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530296"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530296; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530296]").text(description); $(".js-view-count[data-work-id=110530296]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530296; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530296']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530296, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "05495a34eb9b648a08ad7eaf7854e8d8" } } $('.js-work-strip[data-work-id=110530296]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530296,"title":"Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons","translated_title":"","metadata":{"publisher":"National Library of Serbia","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Acta veterinaria"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons","translated_internal_url":"","created_at":"2023-12-04T04:15:49.124-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319749,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319749/thumbnails/1.jpg","file_name":"0567-83151201017M.pdf","download_url":"https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_and_appearance_of_multinuclear.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319749/0567-83151201017M-libre.pdf?1701696010=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_and_appearance_of_multinuclear.pdf\u0026Expires=1732395759\u0026Signature=camGRtE4JNv-L82E2k-80zavTtaaNMqtytCHkiz1t~qVncEBZV57F~h8Q4N~UaviqRpJM9EpdgDbpxpWFMp5h9xZxR10HnqKlw4A603b77lmTmChQKPjEkkeYrmslyIjd4yv401-akTPIxG4krLrOpsEXQ4501B5hTC9aBxVGAoB5py61dCHWBhmcPQrr5mz3A4V61LGNlhGOlpCJrey~pxrXdNAIiApr~UiiW94ABxpDcUEmPXNnGGq3JUtKxGnxkR~0c1-OeRLHyvmfTdOvpaTIQG3zxQTsx4cRqsdchBdR4o7WG-RlsmYsQFahrHHgxQDwMF3RJmxKns2fDNVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319749,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319749/thumbnails/1.jpg","file_name":"0567-83151201017M.pdf","download_url":"https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_and_appearance_of_multinuclear.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319749/0567-83151201017M-libre.pdf?1701696010=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_and_appearance_of_multinuclear.pdf\u0026Expires=1732395759\u0026Signature=camGRtE4JNv-L82E2k-80zavTtaaNMqtytCHkiz1t~qVncEBZV57F~h8Q4N~UaviqRpJM9EpdgDbpxpWFMp5h9xZxR10HnqKlw4A603b77lmTmChQKPjEkkeYrmslyIjd4yv401-akTPIxG4krLrOpsEXQ4501B5hTC9aBxVGAoB5py61dCHWBhmcPQrr5mz3A4V61LGNlhGOlpCJrey~pxrXdNAIiApr~UiiW94ABxpDcUEmPXNnGGq3JUtKxGnxkR~0c1-OeRLHyvmfTdOvpaTIQG3zxQTsx4cRqsdchBdR4o7WG-RlsmYsQFahrHHgxQDwMF3RJmxKns2fDNVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":55267,"name":"Mitosis","url":"https://www.academia.edu/Documents/in/Mitosis"},{"id":76383,"name":"Glioma","url":"https://www.academia.edu/Documents/in/Glioma"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":168351,"name":"Paclitaxel","url":"https://www.academia.edu/Documents/in/Paclitaxel"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712699"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice"><img alt="Research paper thumbnail of Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice">Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice</a></div><div class="wp-workCard_item"><span>Ultrastructural Pathology</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712699"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712699"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712699; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712699]").text(description); $(".js-view-count[data-work-id=95712699]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712699; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712699']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712699, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712699]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712699,"title":"Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice","translated_title":"","metadata":{"publisher":"Informa UK Limited","publication_name":"Ultrastructural Pathology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice","translated_internal_url":"","created_at":"2023-01-25T23:44:59.453-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":473650,"name":"ultrastructural Pathology","url":"https://www.academia.edu/Documents/in/ultrastructural_Pathology"}],"urls":[{"id":28403234,"url":"https://www.tandfonline.com/doi/pdf/10.1080/01913123.2022.2156639"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712698"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat"><img alt="Research paper thumbnail of Appearance of melanocytes in the pineal gland of the mutant Gunn rat" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat">Appearance of melanocytes in the pineal gland of the mutant Gunn rat</a></div><div class="wp-workCard_item"><span>Medical Science Research</span><span>, 1992</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712698"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712698"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712698; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712698]").text(description); $(".js-view-count[data-work-id=95712698]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712698; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712698']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712698, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712698]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712698,"title":"Appearance of melanocytes in the pineal gland of the mutant Gunn rat","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1992,"errors":{}},"publication_name":"Medical Science Research"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat","translated_internal_url":"","created_at":"2023-01-25T23:44:59.346-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":159233,"name":"Medical Science","url":"https://www.academia.edu/Documents/in/Medical_Science"},{"id":613283,"name":"Pineal Gland","url":"https://www.academia.edu/Documents/in/Pineal_Gland"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712697"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients"><img alt="Research paper thumbnail of Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients" class="work-thumbnail" src="https://attachments.academia-assets.com/97819319/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients">Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients</a></div><div class="wp-workCard_item"><span>Tissue and Cell</span><span>, 2018</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b42da3bfe2aee6f1c77b7e6628ae3013" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":97819319,"asset_id":95712697,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712697"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712697"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712697; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712697]").text(description); $(".js-view-count[data-work-id=95712697]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712697; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712697']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712697, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b42da3bfe2aee6f1c77b7e6628ae3013" } } $('.js-work-strip[data-work-id=95712697]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712697,"title":"Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients","translated_title":"","metadata":{"publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2018,"errors":{}},"publication_name":"Tissue and Cell"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients","translated_internal_url":"","created_at":"2023-01-25T23:44:59.175-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":97819319,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/97819319/thumbnails/1.jpg","file_name":"j.tice.2018.04.00520230126-1-li69r4.pdf","download_url":"https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Unusual_shape_and_structure_of_lymphocyt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/97819319/j.tice.2018.04.00520230126-1-li69r4-libre.pdf?1674721692=\u0026response-content-disposition=attachment%3B+filename%3DUnusual_shape_and_structure_of_lymphocyt.pdf\u0026Expires=1732395759\u0026Signature=SYx1oJLgixL2Wkhfof6wtBLsESymBTfGW9x1v6aSk62f~QP5huuvKRMY1Tc7b-tdeNG9XXWwjmDymGYDTP9uU0f~zbah6uQBCvvd7NFIwmJ2ij27gHRAMNjBzRsD0Z5pe-8dbWB7HUnGZnIMYaURjVNBrA9SArzi9h~i3iH480V3MoAmQIUxigqHWPHg4s15LupBHVzhVHDrwT-s89oxbfjJBpG1JWSkaAZpLrxEtQ~fSu8JeI4r7BuQ2JZP2OAhj9XTg7ODsx7LRRsdk8k2HesDt9uBbnUMLBp9t6uhZWmLUCVGO0F8PmdGs~A3lDxTDFqUZqzsX47rRsETlhLWnA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":97819319,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/97819319/thumbnails/1.jpg","file_name":"j.tice.2018.04.00520230126-1-li69r4.pdf","download_url":"https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Unusual_shape_and_structure_of_lymphocyt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/97819319/j.tice.2018.04.00520230126-1-li69r4-libre.pdf?1674721692=\u0026response-content-disposition=attachment%3B+filename%3DUnusual_shape_and_structure_of_lymphocyt.pdf\u0026Expires=1732395759\u0026Signature=SYx1oJLgixL2Wkhfof6wtBLsESymBTfGW9x1v6aSk62f~QP5huuvKRMY1Tc7b-tdeNG9XXWwjmDymGYDTP9uU0f~zbah6uQBCvvd7NFIwmJ2ij27gHRAMNjBzRsD0Z5pe-8dbWB7HUnGZnIMYaURjVNBrA9SArzi9h~i3iH480V3MoAmQIUxigqHWPHg4s15LupBHVzhVHDrwT-s89oxbfjJBpG1JWSkaAZpLrxEtQ~fSu8JeI4r7BuQ2JZP2OAhj9XTg7ODsx7LRRsdk8k2HesDt9uBbnUMLBp9t6uhZWmLUCVGO0F8PmdGs~A3lDxTDFqUZqzsX47rRsETlhLWnA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":23243,"name":"Type 2 Diabetes","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":71297,"name":"Metformin","url":"https://www.academia.edu/Documents/in/Metformin"},{"id":71489,"name":"Hyperinsulinemia","url":"https://www.academia.edu/Documents/in/Hyperinsulinemia"},{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus"},{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology"},{"id":238813,"name":"Chromatin","url":"https://www.academia.edu/Documents/in/Chromatin"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"}],"urls":[{"id":28403233,"url":"https://api.elsevier.com/content/article/PII:S0040816618300880?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712696"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation"><img alt="Research paper thumbnail of The acidophilic nature of neuronal Golgi impregnation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation">The acidophilic nature of neuronal Golgi impregnation</a></div><div class="wp-workCard_item"><span>Acta Histochemica</span><span>, 1998</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712696"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712696"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712696; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712696]").text(description); $(".js-view-count[data-work-id=95712696]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712696; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712696']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712696, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712696]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712696,"title":"The acidophilic nature of neuronal Golgi impregnation","translated_title":"","metadata":{"abstract":"The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.","publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":1998,"errors":{}},"publication_name":"Acta Histochemica"},"translated_abstract":"The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.","internal_url":"https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation","translated_internal_url":"","created_at":"2023-01-25T23:44:58.932-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_acidophilic_nature_of_neuronal_Golgi_impregnation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":530,"name":"Inorganic Chemistry","url":"https://www.academia.edu/Documents/in/Inorganic_Chemistry"},{"id":21466,"name":"Polymers","url":"https://www.academia.edu/Documents/in/Polymers"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":26931,"name":"Nuclear Chemistry","url":"https://www.academia.edu/Documents/in/Nuclear_Chemistry"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":122402,"name":"Nitrates","url":"https://www.academia.edu/Documents/in/Nitrates"},{"id":162982,"name":"Chloride","url":"https://www.academia.edu/Documents/in/Chloride"},{"id":193974,"name":"Neurons","url":"https://www.academia.edu/Documents/in/Neurons"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":541785,"name":"Phosphates","url":"https://www.academia.edu/Documents/in/Phosphates"},{"id":819116,"name":"Formaldehyde","url":"https://www.academia.edu/Documents/in/Formaldehyde"},{"id":843400,"name":"Phosphate","url":"https://www.academia.edu/Documents/in/Phosphate"},{"id":979301,"name":"Golgi Apparatus","url":"https://www.academia.edu/Documents/in/Golgi_Apparatus"},{"id":1295914,"name":"Potassium Chloride","url":"https://www.academia.edu/Documents/in/Potassium_Chloride"},{"id":1436040,"name":"Potassium Compounds","url":"https://www.academia.edu/Documents/in/Potassium_Compounds"},{"id":2550937,"name":"Molecular probes","url":"https://www.academia.edu/Documents/in/Molecular_probes"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"}],"urls":[{"id":28403232,"url":"https://api.elsevier.com/content/article/PII:S0065128198800299?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89649472"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells"><img alt="Research paper thumbnail of Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells" class="work-thumbnail" src="https://attachments.academia-assets.com/93409788/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells">Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells</a></div><div class="wp-workCard_item"><span>Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="60d052b5628c78134051d8840ce54f24" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":93409788,"asset_id":89649472,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89649472"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89649472"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89649472; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89649472]").text(description); $(".js-view-count[data-work-id=89649472]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89649472; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89649472']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89649472, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "60d052b5628c78134051d8840ce54f24" } } $('.js-work-strip[data-work-id=89649472]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89649472,"title":"Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells","translated_title":"","metadata":{"publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"},"translated_abstract":null,"internal_url":"https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells","translated_internal_url":"","created_at":"2022-10-31T15:14:43.821-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93409788,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93409788/thumbnails/1.jpg","file_name":"aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__.pdf","download_url":"https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Autophagy_dependent_and_independent_invo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93409788/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__-libre.pdf?1667254849=\u0026response-content-disposition=attachment%3B+filename%3DAutophagy_dependent_and_independent_invo.pdf\u0026Expires=1732395760\u0026Signature=FhanA-raoaiAEt37u0aaPZcktBQ72aYoEX4H-MteC~H7msCBAjJn0F77zZ9VdFS4uvFnQ4yBoi58hxRBNR1HkprfZDzrnKZcpFfuW8GGJCZxPpQQsyVW8H0wLMtlsBda8lAPL85H28o1k5V9ZYDvi7THam8JgpDIB19tByR8aIY5WJ4wlSsEhPLBkOq4~K2V16n9ZnSR66gHUp6gEb90tUf1PRvxuEnSyzH1avpF3FdvknJlAjlheg-xVZ5~EUCsI5gDQ1KBru9vn31LAQ24jXt~YJMi7CIRtJ4pPKB1vM84rayeSYs5jwelfTV8-5LGV-AytNyakcJYW6s1Yvb~Dg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":93409788,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93409788/thumbnails/1.jpg","file_name":"aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__.pdf","download_url":"https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Autophagy_dependent_and_independent_invo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93409788/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__-libre.pdf?1667254849=\u0026response-content-disposition=attachment%3B+filename%3DAutophagy_dependent_and_independent_invo.pdf\u0026Expires=1732395760\u0026Signature=FhanA-raoaiAEt37u0aaPZcktBQ72aYoEX4H-MteC~H7msCBAjJn0F77zZ9VdFS4uvFnQ4yBoi58hxRBNR1HkprfZDzrnKZcpFfuW8GGJCZxPpQQsyVW8H0wLMtlsBda8lAPL85H28o1k5V9ZYDvi7THam8JgpDIB19tByR8aIY5WJ4wlSsEhPLBkOq4~K2V16n9ZnSR66gHUp6gEb90tUf1PRvxuEnSyzH1avpF3FdvknJlAjlheg-xVZ5~EUCsI5gDQ1KBru9vn31LAQ24jXt~YJMi7CIRtJ4pPKB1vM84rayeSYs5jwelfTV8-5LGV-AytNyakcJYW6s1Yvb~Dg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":14076,"name":"Transmission Electron Microscopy","url":"https://www.academia.edu/Documents/in/Transmission_Electron_Microscopy"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":118582,"name":"Physical sciences","url":"https://www.academia.edu/Documents/in/Physical_sciences"},{"id":172083,"name":"Phosphorylation","url":"https://www.academia.edu/Documents/in/Phosphorylation"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":256805,"name":"Neuroblastoma","url":"https://www.academia.edu/Documents/in/Neuroblastoma"},{"id":550730,"name":"6-Hydroxydopamine","url":"https://www.academia.edu/Documents/in/6-Hydroxydopamine"},{"id":788681,"name":"N-Acetylcysteine","url":"https://www.academia.edu/Documents/in/N-Acetylcysteine"},{"id":1150115,"name":"Sirolimus","url":"https://www.academia.edu/Documents/in/Sirolimus"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1763968,"name":"Gene Expression Regulation","url":"https://www.academia.edu/Documents/in/Gene_Expression_Regulation"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"},{"id":4061411,"name":"acetylcysteine","url":"https://www.academia.edu/Documents/in/acetylcysteine"}],"urls":[{"id":25372696,"url":"https://api.elsevier.com/content/article/PII:S0925443912001925?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84852975"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_"><img alt="Research paper thumbnail of Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]" class="work-thumbnail" src="https://attachments.academia-assets.com/89736593/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_">Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="48dd8af7069e19cf9bc8a69311eec7a4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89736593,"asset_id":84852975,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84852975"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84852975"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84852975; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84852975]").text(description); $(".js-view-count[data-work-id=84852975]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84852975; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84852975']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84852975, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "48dd8af7069e19cf9bc8a69311eec7a4" } } $('.js-work-strip[data-work-id=84852975]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84852975,"title":"Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2013,"errors":{}}},"translated_abstract":null,"internal_url":"https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_","translated_internal_url":"","created_at":"2022-08-15T23:32:00.662-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89736593,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89736593/thumbnails/1.jpg","file_name":"70eef44557b66d0fc3861a04fed16754c546.pdf","download_url":"https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Anion_dependent_Nature_Of_Neuronal_Golgi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89736593/70eef44557b66d0fc3861a04fed16754c546-libre.pdf?1660638903=\u0026response-content-disposition=attachment%3B+filename%3DAnion_dependent_Nature_Of_Neuronal_Golgi.pdf\u0026Expires=1732395760\u0026Signature=RxxO1as6wS5rihAByH01iJlo15cOEiA2HCcJQNy0lcorJlhXoJS3WP~jAFdCEtw2A-~Bn6NXN5xAKNYXKpPjNebKRKK1SOwq-b4y1l2JLnzEODWVpF0dRNQk5jhb8NqaVMOO202Xx81HW6L7wnJZfnlAYu7dDeMyzUlSBQttoCYk~SWiC3nrIdOXumvyr4SAAMxJNPmAA-D1g953~3fvJo6JLO7GSmnzG8XCJKti6s1HhA5M61rYj77zTcOpZLbu3fay-k~gv~vuKESE34yLOUs5VmGrw7DPVaLMnqax3XYygiGTWojLmrzeRuALKhPeeoUDCk27zeDPae5-B8E1VA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_","translated_slug":"","page_count":11,"language":"id","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":89736593,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89736593/thumbnails/1.jpg","file_name":"70eef44557b66d0fc3861a04fed16754c546.pdf","download_url":"https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Anion_dependent_Nature_Of_Neuronal_Golgi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89736593/70eef44557b66d0fc3861a04fed16754c546-libre.pdf?1660638903=\u0026response-content-disposition=attachment%3B+filename%3DAnion_dependent_Nature_Of_Neuronal_Golgi.pdf\u0026Expires=1732395760\u0026Signature=RxxO1as6wS5rihAByH01iJlo15cOEiA2HCcJQNy0lcorJlhXoJS3WP~jAFdCEtw2A-~Bn6NXN5xAKNYXKpPjNebKRKK1SOwq-b4y1l2JLnzEODWVpF0dRNQk5jhb8NqaVMOO202Xx81HW6L7wnJZfnlAYu7dDeMyzUlSBQttoCYk~SWiC3nrIdOXumvyr4SAAMxJNPmAA-D1g953~3fvJo6JLO7GSmnzG8XCJKti6s1HhA5M61rYj77zTcOpZLbu3fay-k~gv~vuKESE34yLOUs5VmGrw7DPVaLMnqax3XYygiGTWojLmrzeRuALKhPeeoUDCk27zeDPae5-B8E1VA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":979301,"name":"Golgi Apparatus","url":"https://www.academia.edu/Documents/in/Golgi_Apparatus"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="79985040"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy"><img alt="Research paper thumbnail of Guidelines for the use and interpretation of assays for monitoring autophagy" class="work-thumbnail" src="https://attachments.academia-assets.com/86517133/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy">Guidelines for the use and interpretation of assays for monitoring autophagy</a></div><div class="wp-workCard_item"><span>Autophagy</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="95cd2707b8d89aede3ec4f57ef65b1d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":86517133,"asset_id":79985040,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="79985040"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="79985040"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 79985040; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=79985040]").text(description); $(".js-view-count[data-work-id=79985040]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 79985040; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='79985040']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 79985040, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "95cd2707b8d89aede3ec4f57ef65b1d4" } } $('.js-work-strip[data-work-id=79985040]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":79985040,"title":"Guidelines for the use and interpretation of assays for monitoring autophagy","translated_title":"","metadata":{"publisher":"Informa UK Limited","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Autophagy"},"translated_abstract":null,"internal_url":"https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy","translated_internal_url":"","created_at":"2022-05-26T09:26:32.354-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":86517133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/86517133/thumbnails/1.jpg","file_name":"2012AUTO0036.pdf","download_url":"https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Guidelines_for_the_use_and_interpretatio.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/86517133/2012AUTO0036-libre.pdf?1653583098=\u0026response-content-disposition=attachment%3B+filename%3DGuidelines_for_the_use_and_interpretatio.pdf\u0026Expires=1732395760\u0026Signature=bCuzObsNGSfQhTYbEJ6MCefBwbjBJ3GGMy-15Kwcomc5FS2~tlWC8zIIjMtAqeSwMLsEAcs1kVDtIKWVMcFvw540rUmMZAtoQO5jFnGPoXlxsfCW-659fHGg-WjqEZAVa5kaKUCF11zmr~4EMod3M~b2LYtzqvokbB2-YgHLxOxw5QRymODeKHXqmN3LiGbJ9a72JSNAjjzJXMLP6konzW7-QZET4iFJ0fQBqdlTnybu0P75qzpg6iUDVdifIgjUoXES33umyNscFbsRmFqkFGQJ0gI8wv0MchAHOa43dkW0waVFedZgR1ddv5KV3RQP8nO2orJIEwetLNAxh3aVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy","translated_slug":"","page_count":100,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":86517133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/86517133/thumbnails/1.jpg","file_name":"2012AUTO0036.pdf","download_url":"https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Guidelines_for_the_use_and_interpretatio.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/86517133/2012AUTO0036-libre.pdf?1653583098=\u0026response-content-disposition=attachment%3B+filename%3DGuidelines_for_the_use_and_interpretatio.pdf\u0026Expires=1732395760\u0026Signature=bCuzObsNGSfQhTYbEJ6MCefBwbjBJ3GGMy-15Kwcomc5FS2~tlWC8zIIjMtAqeSwMLsEAcs1kVDtIKWVMcFvw540rUmMZAtoQO5jFnGPoXlxsfCW-659fHGg-WjqEZAVa5kaKUCF11zmr~4EMod3M~b2LYtzqvokbB2-YgHLxOxw5QRymODeKHXqmN3LiGbJ9a72JSNAjjzJXMLP6konzW7-QZET4iFJ0fQBqdlTnybu0P75qzpg6iUDVdifIgjUoXES33umyNscFbsRmFqkFGQJ0gI8wv0MchAHOa43dkW0waVFedZgR1ddv5KV3RQP8nO2orJIEwetLNAxh3aVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry"},{"id":7700,"name":"Fluorescence Microscopy","url":"https://www.academia.edu/Documents/in/Fluorescence_Microscopy"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":13848,"name":"Deep Ecology","url":"https://www.academia.edu/Documents/in/Deep_Ecology"},{"id":14406,"name":"Health","url":"https://www.academia.edu/Documents/in/Health"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":37782,"name":"Cell Culture","url":"https://www.academia.edu/Documents/in/Cell_Culture"},{"id":37783,"name":"Assay Development","url":"https://www.academia.edu/Documents/in/Assay_Development"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":72527,"name":"Ch","url":"https://www.academia.edu/Documents/in/Ch"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":112576,"name":"Cell Death","url":"https://www.academia.edu/Documents/in/Cell_Death"},{"id":136787,"name":"ER stress","url":"https://www.academia.edu/Documents/in/ER_stress"},{"id":771990,"name":"Eukaryotic Cells","url":"https://www.academia.edu/Documents/in/Eukaryotic_Cells"},{"id":833228,"name":"Human Disease","url":"https://www.academia.edu/Documents/in/Human_Disease"},{"id":1109769,"name":"Biological Assay","url":"https://www.academia.edu/Documents/in/Biological_Assay"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"}],"urls":[{"id":20803294,"url":"http://www.tandfonline.com/doi/pdf/10.4161/auto.19496"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="73640096"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced"><img alt="Research paper thumbnail of Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced" class="work-thumbnail" src="https://attachments.academia-assets.com/82082814/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced">Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study investigated the role of autophagy, a cellular self-digestion process, in the c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b2ce32d59c987881a9f466e9a5e0bd99" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":82082814,"asset_id":73640096,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="73640096"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="73640096"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 73640096; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=73640096]").text(description); $(".js-view-count[data-work-id=73640096]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 73640096; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='73640096']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 73640096, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b2ce32d59c987881a9f466e9a5e0bd99" } } $('.js-work-strip[data-work-id=73640096]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":73640096,"title":"Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced","translated_title":"","metadata":{"abstract":"The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...","publication_date":{"day":null,"month":null,"year":2016,"errors":{}}},"translated_abstract":"The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...","internal_url":"https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced","translated_internal_url":"","created_at":"2022-03-12T23:23:11.041-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":82082814,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/82082814/thumbnails/1.jpg","file_name":"asset.pdf","download_url":"https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inhibition_of_mTOR_Dependent_Autophagy_S.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/82082814/asset-libre.pdf?1647158805=\u0026response-content-disposition=attachment%3B+filename%3DInhibition_of_mTOR_Dependent_Autophagy_S.pdf\u0026Expires=1732395760\u0026Signature=TOrXy1Xz-IgkYZDidVznemsdjJJJJkx0l1mh1gkQD3yDqZ~wpW7Y39Bjd7XbVvH4YoDX7UwvThOqrHfwhgd7YPH~uNGM1o5R7mJbiEc2AWpX8o4HqvPBv7L-Em1zMR~rwWgEzFVUxUx1n4OJS40CEvdZIEo0lgF39vjNsNmg3veuC489LwCKa8LrdEjnh6nz~buaH9K9yS977bicnRdfLZ7cKOuy1NBls7Q9C2sIgAtyTZl05IYy8NvLoXNvD9Q2oF148zfpgnA5UBRgFVP3H8KPjVgzKXh9vT4t440J1328vhtE0I433b3etCQXiRU~hlOO9PeoJvLbckoOiEbFWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":82082814,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/82082814/thumbnails/1.jpg","file_name":"asset.pdf","download_url":"https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inhibition_of_mTOR_Dependent_Autophagy_S.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/82082814/asset-libre.pdf?1647158805=\u0026response-content-disposition=attachment%3B+filename%3DInhibition_of_mTOR_Dependent_Autophagy_S.pdf\u0026Expires=1732395760\u0026Signature=TOrXy1Xz-IgkYZDidVznemsdjJJJJkx0l1mh1gkQD3yDqZ~wpW7Y39Bjd7XbVvH4YoDX7UwvThOqrHfwhgd7YPH~uNGM1o5R7mJbiEc2AWpX8o4HqvPBv7L-Em1zMR~rwWgEzFVUxUx1n4OJS40CEvdZIEo0lgF39vjNsNmg3veuC489LwCKa8LrdEjnh6nz~buaH9K9yS977bicnRdfLZ7cKOuy1NBls7Q9C2sIgAtyTZl05IYy8NvLoXNvD9Q2oF148zfpgnA5UBRgFVP3H8KPjVgzKXh9vT4t440J1328vhtE0I433b3etCQXiRU~hlOO9PeoJvLbckoOiEbFWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction"},{"id":51121,"name":"RNA interference","url":"https://www.academia.edu/Documents/in/RNA_interference"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"}],"urls":[{"id":18462112,"url":"http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.937.1204\u0026rep=rep1\u0026type=pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="64199069"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells"><img alt="Research paper thumbnail of Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells">Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells</a></div><div class="wp-workCard_item"><span>PLOS ONE</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="64199069"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="64199069"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 64199069; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=64199069]").text(description); $(".js-view-count[data-work-id=64199069]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 64199069; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='64199069']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 64199069, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=64199069]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":64199069,"title":"Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"PLOS ONE"},"translated_abstract":null,"internal_url":"https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells","translated_internal_url":"","created_at":"2021-12-14T23:24:55.175-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="11606771" id="papers"><div class="js-work-strip profile--work_container" data-work-id="110530399"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome"><img alt="Research paper thumbnail of Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome">Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome</a></div><div class="wp-workCard_item"><span>Forensic Science Medicine and Pathology</span><span>, Feb 21, 2023</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530399"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530399"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530399; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530399]").text(description); $(".js-view-count[data-work-id=110530399]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530399; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530399']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530399, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530399]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530399,"title":"Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome","translated_title":"","metadata":{"publisher":"Springer Science+Business Media","publication_date":{"day":21,"month":2,"year":2023,"errors":{}},"publication_name":"Forensic Science Medicine and Pathology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530399/Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome","translated_internal_url":"","created_at":"2023-12-04T04:17:04.681-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Micromorphological_features_and_interleukin_6_8_and_18_expressions_in_post_mortem_lung_tissue_in_cases_with_acute_respiratory_distress_syndrome","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":165,"name":"Pathology","url":"https://www.academia.edu/Documents/in/Pathology"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":197297,"name":"Lung","url":"https://www.academia.edu/Documents/in/Lung"},{"id":314484,"name":"Autopsy","url":"https://www.academia.edu/Documents/in/Autopsy"},{"id":463111,"name":"Ards","url":"https://www.academia.edu/Documents/in/Ards"}],"urls":[{"id":36415062,"url":"https://doi.org/10.1007/s12024-022-00572-4"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530395"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS"><img alt="Research paper thumbnail of INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS">INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS</a></div><div class="wp-workCard_item"><span>Biochemical Society Transactions</span><span>, Nov 1, 1996</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530395"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530395"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530395; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530395]").text(description); $(".js-view-count[data-work-id=110530395]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530395; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530395']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530395, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530395]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530395,"title":"INHIBITION OF (Na,K)ATPase IN THYMOCYTES REDUCES APOPTOSIS INDUCED BY MICROTUBULE-DISRUPTING AGENTS","translated_title":"","metadata":{"publisher":"Portland Press","publication_date":{"day":1,"month":11,"year":1996,"errors":{}},"publication_name":"Biochemical Society Transactions"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530395/INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS","translated_internal_url":"","created_at":"2023-12-04T04:17:01.494-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"INHIBITION_OF_Na_K_ATPase_IN_THYMOCYTES_REDUCES_APOPTOSIS_INDUCED_BY_MICROTUBULE_DISRUPTING_AGENTS","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"}],"urls":[{"id":36415058,"url":"https://doi.org/10.1042/bst024612sa"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530394"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_"><img alt="Research paper thumbnail of [Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_">[Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, 1980</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530394"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530394"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530394; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530394]").text(description); $(".js-view-count[data-work-id=110530394]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530394; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530394']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530394, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530394]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530394,"title":"[Morphologic study of Wagner-Meissner corpuscles in the skin of the right index finger during ontogenetic development]","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1980,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530394/_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_","translated_internal_url":"","created_at":"2023-12-04T04:17:01.003-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Morphologic_study_of_Wagner_Meissner_corpuscles_in_the_skin_of_the_right_index_finger_during_ontogenetic_development_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":55608,"name":"Ontogeny","url":"https://www.academia.edu/Documents/in/Ontogeny"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":86150,"name":"Touch","url":"https://www.academia.edu/Documents/in/Touch"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":128559,"name":"Mechanoreceptors","url":"https://www.academia.edu/Documents/in/Mechanoreceptors"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":1028516,"name":"Fingers","url":"https://www.academia.edu/Documents/in/Fingers"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"},{"id":3763168,"name":"Index Finger","url":"https://www.academia.edu/Documents/in/Index_Finger"}],"urls":[{"id":36415057,"url":"https://pubmed.ncbi.nlm.nih.gov/7233262"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530393"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_"><img alt="Research paper thumbnail of [Morphology and function of the neglected ligament of the foot]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_">[Morphology and function of the neglected ligament of the foot]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Apr 1, 1984</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530393"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530393"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530393; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530393]").text(description); $(".js-view-count[data-work-id=110530393]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530393; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530393']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530393, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530393]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530393,"title":"[Morphology and function of the neglected ligament of the foot]","translated_title":"","metadata":{"publication_date":{"day":1,"month":4,"year":1984,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530393/_Morphology_and_function_of_the_neglected_ligament_of_the_foot_","translated_internal_url":"","created_at":"2023-12-04T04:17:00.587-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Morphology_and_function_of_the_neglected_ligament_of_the_foot_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":24554,"name":"Ligament","url":"https://www.academia.edu/Documents/in/Ligament"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":449523,"name":"Foot","url":"https://www.academia.edu/Documents/in/Foot"},{"id":990519,"name":"Ligaments","url":"https://www.academia.edu/Documents/in/Ligaments"}],"urls":[{"id":36415056,"url":"https://pubmed.ncbi.nlm.nih.gov/6515479"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530391"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_"><img alt="Research paper thumbnail of [Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_">[Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Feb 1, 1980</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530391"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530391"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530391; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530391]").text(description); $(".js-view-count[data-work-id=110530391]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530391; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530391']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530391, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530391]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530391,"title":"[Development of Wagner-Meissner corpuscles in the thenar and hypothenar skin]","translated_title":"","metadata":{"publication_date":{"day":1,"month":2,"year":1980,"errors":{}},"publication_name":"PubMed"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530391/_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_","translated_internal_url":"","created_at":"2023-12-04T04:17:00.086-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Development_of_Wagner_Meissner_corpuscles_in_the_thenar_and_hypothenar_skin_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":86150,"name":"Touch","url":"https://www.academia.edu/Documents/in/Touch"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":128559,"name":"Mechanoreceptors","url":"https://www.academia.edu/Documents/in/Mechanoreceptors"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":500368,"name":"Hand","url":"https://www.academia.edu/Documents/in/Hand"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"}],"urls":[{"id":36415054,"url":"https://pubmed.ncbi.nlm.nih.gov/7244858"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530389"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro"><img alt="Research paper thumbnail of Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro" class="work-thumbnail" src="https://attachments.academia-assets.com/108319828/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro">Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Jun 1, 1995</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d909bf8b39dd294f1dc497e711d0c292" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319828,"asset_id":110530389,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530389"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530389"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530389; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530389]").text(description); $(".js-view-count[data-work-id=110530389]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530389; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530389']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530389, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "d909bf8b39dd294f1dc497e711d0c292" } } $('.js-work-strip[data-work-id=110530389]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530389,"title":"Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro","translated_title":"","metadata":{"abstract":"Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.","publication_date":{"day":1,"month":6,"year":1995,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"Disruption of cytoplasmic and spindle microtubules by colchicine or nocodazole increases mitotic index, but it also enhances apoptosis in isolated mouse thymocytes; the apoptotic index exceeds 20% after 4 hours of incubation with either drug (5% in controls). Apoptosis was confirmed by DNA fragmentation, and was blocked by calcium chelators and inhibitors of protein synthesis. The apoptotic effect of microtubule disrupting drugs (MDD) was directed to interphase thymocytes and was independent on MDD action on mitotic cells. However, cell death of mitotically arrested cells showed ultrastructural changes similar in many aspects to apoptosis.","internal_url":"https://www.academia.edu/110530389/Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro","translated_internal_url":"","created_at":"2023-12-04T04:16:59.595-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319828/thumbnails/1.jpg","file_name":"359176980.pdf","download_url":"https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_induced_by_microtubule_disrupt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319828/359176980-libre.pdf?1701696019=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_induced_by_microtubule_disrupt.pdf\u0026Expires=1732395759\u0026Signature=DcEauM9bCj1sZeB57yEF~UvcxzPCb3cRXQWXGqpBMJ77QqwKLfMrnW~ZSe~3uJoJwyEEBQrBtVMM3YW-kttpV0iVg-DMYNIHZxkaurC8ehFpvdliGoJMzNquGBoDStFwACcA-B1d1-0w6df15mmRwtqwDpWWK9aLPbg3ox1XN13EZFNuBMB~CYlziNYB7bpMlJCuueTSXOY2KtiwucunmZSLbSR5wIXtUqYkM9af5e7LvxfgasKBKvKJ2bkjyXE0logif3Tc3PenGCIJ3yXGeAnUVjljkbQR1~2ls4nvpWbdWCLQpMHsmT~KVGNNojRRGa50BZUm-bMFHc0xVzjtGw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptosis_induced_by_microtubule_disrupting_drugs_in_normal_murine_thymocytes_in_vitro","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319828/thumbnails/1.jpg","file_name":"359176980.pdf","download_url":"https://www.academia.edu/attachments/108319828/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_induced_by_microtubule_disrupt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319828/359176980-libre.pdf?1701696019=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_induced_by_microtubule_disrupt.pdf\u0026Expires=1732395759\u0026Signature=DcEauM9bCj1sZeB57yEF~UvcxzPCb3cRXQWXGqpBMJ77QqwKLfMrnW~ZSe~3uJoJwyEEBQrBtVMM3YW-kttpV0iVg-DMYNIHZxkaurC8ehFpvdliGoJMzNquGBoDStFwACcA-B1d1-0w6df15mmRwtqwDpWWK9aLPbg3ox1XN13EZFNuBMB~CYlziNYB7bpMlJCuueTSXOY2KtiwucunmZSLbSR5wIXtUqYkM9af5e7LvxfgasKBKvKJ2bkjyXE0logif3Tc3PenGCIJ3yXGeAnUVjljkbQR1~2ls4nvpWbdWCLQpMHsmT~KVGNNojRRGa50BZUm-bMFHc0xVzjtGw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":10655,"name":"Scanning Electron Microscopy","url":"https://www.academia.edu/Documents/in/Scanning_Electron_Microscopy"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":55267,"name":"Mitosis","url":"https://www.academia.edu/Documents/in/Mitosis"},{"id":84910,"name":"Mouse","url":"https://www.academia.edu/Documents/in/Mouse"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":172350,"name":"Microtubules","url":"https://www.academia.edu/Documents/in/Microtubules"},{"id":175490,"name":"Programmed cell death","url":"https://www.academia.edu/Documents/in/Programmed_cell_death"},{"id":371370,"name":"Colchicine","url":"https://www.academia.edu/Documents/in/Colchicine"},{"id":1166930,"name":"Cytoplasm","url":"https://www.academia.edu/Documents/in/Cytoplasm"},{"id":1168109,"name":"Mitotic Index","url":"https://www.academia.edu/Documents/in/Mitotic_Index"},{"id":1959383,"name":"Interphase","url":"https://www.academia.edu/Documents/in/Interphase"},{"id":2256666,"name":"DNA fragmentation","url":"https://www.academia.edu/Documents/in/DNA_fragmentation"},{"id":3120495,"name":"Thymocytes","url":"https://www.academia.edu/Documents/in/Thymocytes"}],"urls":[{"id":36415052,"url":"https://pubmed.ncbi.nlm.nih.gov/8714746"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530385"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1"><img alt="Research paper thumbnail of Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1" class="work-thumbnail" src="https://attachments.academia-assets.com/108319846/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1">Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1</a></div><div class="wp-workCard_item"><span>Psychopharmacology</span><span>, Feb 5, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8116ee6a5830a8b819b2bddbce53ec16" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319846,"asset_id":110530385,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530385"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530385"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530385; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530385]").text(description); $(".js-view-count[data-work-id=110530385]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530385; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530385']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530385, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8116ee6a5830a8b819b2bddbce53ec16" } } $('.js-work-strip[data-work-id=110530385]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530385,"title":"Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1","translated_title":"","metadata":{"publisher":"Springer Science+Business Media","publication_date":{"day":5,"month":2,"year":2013,"errors":{}},"publication_name":"Psychopharmacology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530385/Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1","translated_internal_url":"","created_at":"2023-12-04T04:16:57.791-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319846,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319846/thumbnails/1.jpg","file_name":"s00213-013-2999-720231204-1-6xyz46.pdf","download_url":"https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Perinatal_phencyclidine_administration_d.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319846/s00213-013-2999-720231204-1-6xyz46-libre.pdf?1701696002=\u0026response-content-disposition=attachment%3B+filename%3DPerinatal_phencyclidine_administration_d.pdf\u0026Expires=1732395759\u0026Signature=Rapn1kXe8o7YlZ-MLoLgQZ6WTNX3z~IoXUlydcFc88mMIQ9vbB3iYlvGiXaBZLPsH0WD6czBWXrugSu~mTHCw1rX4CTCPaczLO0Zf8OhfnKuNzzlIDsF0E7RmiCfqajtm~Vu4GLDBbEt4yfE1Fx9Em46U6Z2EBl~n90UAfJrhzr4oBwfkwTj~dqZAeyj9Ulvwaiky7mk4B-JJra6fn33hVII6~dJhthd2LP6tt0OKXlclqtvyJHqxxLQVDpEBkAKHjUwnz1UeQ8MCd9bmW7tcBpf9Asq6UghGQ5kgiUHlke~vRM2qOixhnhd9J-oEmrlkBwqL8c-BUT8lGLASLeQeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Perinatal_phencyclidine_administration_decreases_the_density_of_cortical_interneurons_and_increases_the_expression_of_neuregulin_1","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319846,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319846/thumbnails/1.jpg","file_name":"s00213-013-2999-720231204-1-6xyz46.pdf","download_url":"https://www.academia.edu/attachments/108319846/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Perinatal_phencyclidine_administration_d.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319846/s00213-013-2999-720231204-1-6xyz46-libre.pdf?1701696002=\u0026response-content-disposition=attachment%3B+filename%3DPerinatal_phencyclidine_administration_d.pdf\u0026Expires=1732395759\u0026Signature=Rapn1kXe8o7YlZ-MLoLgQZ6WTNX3z~IoXUlydcFc88mMIQ9vbB3iYlvGiXaBZLPsH0WD6czBWXrugSu~mTHCw1rX4CTCPaczLO0Zf8OhfnKuNzzlIDsF0E7RmiCfqajtm~Vu4GLDBbEt4yfE1Fx9Em46U6Z2EBl~n90UAfJrhzr4oBwfkwTj~dqZAeyj9Ulvwaiky7mk4B-JJra6fn33hVII6~dJhthd2LP6tt0OKXlclqtvyJHqxxLQVDpEBkAKHjUwnz1UeQ8MCd9bmW7tcBpf9Asq6UghGQ5kgiUHlke~vRM2qOixhnhd9J-oEmrlkBwqL8c-BUT8lGLASLeQeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience"},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":2047,"name":"Psychopharmacology","url":"https://www.academia.edu/Documents/in/Psychopharmacology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":35881,"name":"Interneuron","url":"https://www.academia.edu/Documents/in/Interneuron"},{"id":57556,"name":"Hippocampus","url":"https://www.academia.edu/Documents/in/Hippocampus"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":246876,"name":"Dentate Gyrus","url":"https://www.academia.edu/Documents/in/Dentate_Gyrus"},{"id":251026,"name":"Phencyclidine","url":"https://www.academia.edu/Documents/in/Phencyclidine"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":1147511,"name":"Reelin","url":"https://www.academia.edu/Documents/in/Reelin"},{"id":1287048,"name":"Interneurons","url":"https://www.academia.edu/Documents/in/Interneurons"},{"id":1763968,"name":"Gene Expression Regulation","url":"https://www.academia.edu/Documents/in/Gene_Expression_Regulation"},{"id":2226469,"name":"Hippocampal formation","url":"https://www.academia.edu/Documents/in/Hippocampal_formation"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[{"id":36415049,"url":"https://doi.org/10.1007/s00213-013-2999-7"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530383"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma"><img alt="Research paper thumbnail of Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma" class="work-thumbnail" src="https://attachments.academia-assets.com/108319762/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma">Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma</a></div><div class="wp-workCard_item"><span>Oncology Research and Treatment</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies ba...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) &gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="18201f61cb01ef2842afa8dcc1e7074b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319762,"asset_id":110530383,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530383"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530383"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530383; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530383]").text(description); $(".js-view-count[data-work-id=110530383]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530383; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530383']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530383, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "18201f61cb01ef2842afa8dcc1e7074b" } } $('.js-work-strip[data-work-id=110530383]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530383,"title":"Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma","translated_title":"","metadata":{"abstract":"Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) \u0026gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...","publisher":"S. Karger AG","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Oncology Research and Treatment"},"translated_abstract":"Background: Although Hodgkin’s lymphoma (HL) is a curable cancer, current treatment strategies based on risk stratification and response modulation are not precise enough. The predictive power of biological and morphological parameters is controversial, with prognostic models not reaching wide acceptance. Patients and Methods: We analyzed the prognostic relevance of 8 parameters in 85 advancedstage classical HL patients, in order to determine whether tissue-based variables could add prognostic value to standard clinical parameters, thus contributing to better risk stratification at presentation. Results: Univariate analysis confirmed 5 indicators of shorter overall survival (OS): Bcl-2 overexpression; increased CD68+ tumor-associated macrophages (TAM); international prognostic score (IPS) \u0026gt; 2; bulky disease; and total lymph node involvement (TLNI) with regard to neoplastic and inflammatory cells. Apart from TLNI, these parameters influenced lower event-free survival (EFS). Multiv...","internal_url":"https://www.academia.edu/110530383/Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma","translated_internal_url":"","created_at":"2023-12-04T04:16:56.694-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319762,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319762/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319762/343664-libre.pdf?1701696018=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=JeSfGqDWmvQtPgBpRcLvng5f7h2NH3tgnuwvcSefUBz2U5QX69GuTT9kMG~D8qf1fuLmjZlKw6Qv0nwwEHxkUV2rFAlCgkBlzhDdxjDZx~tjo02qtwPnISpAdwlDdphJisDZwo~qJ~uxQxGT1vo5dANYG7DjmPQxS4Uk-keO6EBFe7r5FZTTdrhDWLe-TsLmjVFn2YldHHd3vMgXjHKoHuXWGx3xQeIRtxvzxPalsFBHC0pCcEaVeRwT2uvtlIMN-zlPtqQPjE-8cwSL6PrpGfD-aS1H2dp-wp3BnYzG4R-XPtNRSQuleAJw9tolFp5M-5IajJG8BV1shSM4gc7wlA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Prognostic_Significance_of_Bcl_2_Tumor_Associated_Macrophages_and_Total_Neoplastic_and_Inflammatory_Lymph_Node_Involvement_in_Advanced_Stage_Classical_Hodgkin_s_Lymphoma","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319762,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319762/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319762/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319762/343664-libre.pdf?1701696018=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=JeSfGqDWmvQtPgBpRcLvng5f7h2NH3tgnuwvcSefUBz2U5QX69GuTT9kMG~D8qf1fuLmjZlKw6Qv0nwwEHxkUV2rFAlCgkBlzhDdxjDZx~tjo02qtwPnISpAdwlDdphJisDZwo~qJ~uxQxGT1vo5dANYG7DjmPQxS4Uk-keO6EBFe7r5FZTTdrhDWLe-TsLmjVFn2YldHHd3vMgXjHKoHuXWGx3xQeIRtxvzxPalsFBHC0pCcEaVeRwT2uvtlIMN-zlPtqQPjE-8cwSL6PrpGfD-aS1H2dp-wp3BnYzG4R-XPtNRSQuleAJw9tolFp5M-5IajJG8BV1shSM4gc7wlA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":108319763,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319763/thumbnails/1.jpg","file_name":"343664.pdf","download_url":"https://www.academia.edu/attachments/108319763/download_file","bulk_download_file_name":"Prognostic_Significance_of_Bcl_2_Tumor_A.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319763/343664-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DPrognostic_Significance_of_Bcl_2_Tumor_A.pdf\u0026Expires=1732395759\u0026Signature=gYXySWlvGW6mS-CKPz9Y1blmCLSR40N7N2R163L~AT9-UdkmY-ka0g7aTg-WzlNxSuaCMazwCmg~RianOgCunWSYARYQbUViN0pH~So3WSi2tpX4GOYw2oTfIt-~0da7Q8R92bfBBNOC1IRZkI3BHDloJnU0dTlQ021EkbcQ7GPZFrZTImCr6iNRWnWE-hTaZjqgDFBpnSFiEx-jxv4IFiqr5v6XEdB1rZ7Pp6PFJW4efobDt32Mk91~W1ZihfBKMIub1SlL4Sx5uFkYOzoIZG2KX3fUGNZtQzMPL-rcoH9SfAHbcUn9irzmlvxLmYk9bdyE6BefgjNdykluQqwn7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology"},{"id":17491,"name":"Macrophages","url":"https://www.academia.edu/Documents/in/Macrophages"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28973,"name":"Comorbidity","url":"https://www.academia.edu/Documents/in/Comorbidity"},{"id":55269,"name":"Lymphoma","url":"https://www.academia.edu/Documents/in/Lymphoma"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":216943,"name":"CD","url":"https://www.academia.edu/Documents/in/CD"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":911025,"name":"Lymph Node","url":"https://www.academia.edu/Documents/in/Lymph_Node"},{"id":1187753,"name":"Onkologie","url":"https://www.academia.edu/Documents/in/Onkologie"},{"id":1350756,"name":"Hodgkin disease","url":"https://www.academia.edu/Documents/in/Hodgkin_disease"},{"id":2718075,"name":"lymphangitis","url":"https://www.academia.edu/Documents/in/lymphangitis"}],"urls":[{"id":36415047,"url":"https://www.karger.com/Article/Pdf/343664"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530381"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma"><img alt="Research paper thumbnail of The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma">The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma</a></div><div class="wp-workCard_item"><span>Leukemia &amp; Lymphoma</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable progno...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530381"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530381"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530381; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530381]").text(description); $(".js-view-count[data-work-id=110530381]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530381; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530381']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530381, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=110530381]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530381,"title":"The prognostic relevance of tumor associated macrophages in advanced stage classical Hodgkin lymphoma","translated_title":"","metadata":{"abstract":"Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.","publisher":"Informa UK Limited","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Leukemia \u0026amp; Lymphoma"},"translated_abstract":"Although the treatment of Hodgkin lymphoma (HL) has been improved, distinguishing reliable prognostic biomarkers could better stratify patients for more effective treatment. We analyzed the prognostic relevance of CD68+ tumor-associated macrophages (TAMs) by immunohistochemical analysis at diagnosis and standard clinical parameters in 52 ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine)-treated patients with advanced stage classical HL (cHL). Patients with \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;25% CD68+ TAMs compared to those with ≤25% had worse 5-year overall survival (45% vs. 77%, log-rank p = 0.019) and showed a trend toward shorter 5-year event-free survival (51% vs. 71%, log-rank p = 0.19). Additionally, no significant correlation with selected clinical features was found. Significantly shorter 5-year overall survival was associated with International Prognostic Score (IPS) \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, bulky disease, elevated erythrocyte sedimentation rate (log-rank test, p = 0.003, p = 0.049, p = 0.007, respectively). In multivariate analysis, increased CD68+TAMs, IPS \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2, and bulky disease were identified as independent prognostic factors for overall survival (Cox multivariate model, p = 0.006, p = 0.007, p = 0.013, respectively). Tumor-associated macrophages represent a potential prognostic biomarker which could contribute to better risk stratification of patients with cHL.","internal_url":"https://www.academia.edu/110530381/The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma","translated_internal_url":"","created_at":"2023-12-04T04:16:55.708-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_prognostic_relevance_of_tumor_associated_macrophages_in_advanced_stage_classical_Hodgkin_lymphoma","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology"},{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia"},{"id":17491,"name":"Macrophages","url":"https://www.academia.edu/Documents/in/Macrophages"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":418283,"name":"Proportional hazards model","url":"https://www.academia.edu/Documents/in/Proportional_hazards_model"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis"},{"id":1350756,"name":"Hodgkin disease","url":"https://www.academia.edu/Documents/in/Hodgkin_disease"},{"id":3953591,"name":"ABVD","url":"https://www.academia.edu/Documents/in/ABVD"}],"urls":[{"id":36415045,"url":"http://www.tandfonline.com/doi/pdf/10.3109/10428194.2011.580026"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530379"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant"><img alt="Research paper thumbnail of Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant" class="work-thumbnail" src="https://attachments.academia-assets.com/108319761/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant">Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant</a></div><div class="wp-workCard_item"><span>Clinical and Experimental Immunology</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9bd70c54dc9b97d9e1cfdce71cbee0e6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319761,"asset_id":110530379,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530379"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530379"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530379; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530379]").text(description); $(".js-view-count[data-work-id=110530379]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530379; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530379']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530379, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9bd70c54dc9b97d9e1cfdce71cbee0e6" } } $('.js-work-strip[data-work-id=110530379]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530379,"title":"Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant","translated_title":"","metadata":{"abstract":"SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...","publisher":"Oxford University Press (OUP)","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Clinical and Experimental Immunology"},"translated_abstract":"SUMMARYExperimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE produce non-specific effects interfering with the mechanisms involved in the autoimmune response to the central nervous system (CNS) tissue. It is therefore important to establish a more suitable model of EAE for analysis of autoimmune phenomena resembling those operative in MS. Here we report that EAE can be induced regularly in Dark Agouti (DA) strain of rats with spinal cord tissue without any adjuvant, as judged by both clinical and histological parameters. The incidence and severity of EAE depended on the origin of the encephalitogen, the rat versus guinea pig spinal cord homogenate being more efficient. Furthermore, EAE could be reinduced in animals which had recovered from disease that had been induced actively with encephalitogen alone, suggesting the role of adjuvant-generated non-specific mechani...","internal_url":"https://www.academia.edu/110530379/Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant","translated_internal_url":"","created_at":"2023-12-04T04:16:55.085-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319761,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319761/thumbnails/1.jpg","file_name":"j.1365-2249.2004.02418.x.pdf","download_url":"https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Induction_of_experimental_autoimmune_enc.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319761/j.1365-2249.2004.02418.x-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DInduction_of_experimental_autoimmune_enc.pdf\u0026Expires=1732395759\u0026Signature=H9rv5GO~IIUbWbUqdWzr07mXragHUJti0remnvad3a6n6ietmDipgLo4VAhxNeN7QgcIDRxb7Nh7tU30MIc0vs0FdTuU~EYx14tunNvx-vgBhDFmN3mTOn8cvmQvxzdda4Er5Bs72Gma4vDks-vJiJDh-t~BQH0t7Gf6kI~NZXyipFYwnUdjMjh1WSi499sFhp3uONIZ5YMNNc~bq2~MiFAaFVD5Is6KP4TYP1Lxho6C80WfFn59T41OghmSRnfu1bV6wxepN9SIca4sHuEs3C3GuJsW0BngRUSawdgLbMr5dAULMijICpRVswSMlf3m71LonS3mUFhEl1E551L89Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Induction_of_experimental_autoimmune_encephalomyelitis_in_Dark_Agouti_rats_without_adjuvant","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319761,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319761/thumbnails/1.jpg","file_name":"j.1365-2249.2004.02418.x.pdf","download_url":"https://www.academia.edu/attachments/108319761/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Induction_of_experimental_autoimmune_enc.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319761/j.1365-2249.2004.02418.x-libre.pdf?1701696013=\u0026response-content-disposition=attachment%3B+filename%3DInduction_of_experimental_autoimmune_enc.pdf\u0026Expires=1732395759\u0026Signature=H9rv5GO~IIUbWbUqdWzr07mXragHUJti0remnvad3a6n6ietmDipgLo4VAhxNeN7QgcIDRxb7Nh7tU30MIc0vs0FdTuU~EYx14tunNvx-vgBhDFmN3mTOn8cvmQvxzdda4Er5Bs72Gma4vDks-vJiJDh-t~BQH0t7Gf6kI~NZXyipFYwnUdjMjh1WSi499sFhp3uONIZ5YMNNc~bq2~MiFAaFVD5Is6KP4TYP1Lxho6C80WfFn59T41OghmSRnfu1bV6wxepN9SIca4sHuEs3C3GuJsW0BngRUSawdgLbMr5dAULMijICpRVswSMlf3m71LonS3mUFhEl1E551L89Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis"},{"id":12320,"name":"Autoimmunity","url":"https://www.academia.edu/Documents/in/Autoimmunity"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":66613,"name":"Autoimmune Disease","url":"https://www.academia.edu/Documents/in/Autoimmune_Disease"},{"id":99421,"name":"Spinal Cord","url":"https://www.academia.edu/Documents/in/Spinal_Cord"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System"},{"id":989400,"name":"Experimental Autoimmune Encephalomyelitis","url":"https://www.academia.edu/Documents/in/Experimental_Autoimmune_Encephalomyelitis"},{"id":1425672,"name":"Encephalomyelitis","url":"https://www.academia.edu/Documents/in/Encephalomyelitis"},{"id":1485245,"name":"Adjuvant","url":"https://www.academia.edu/Documents/in/Adjuvant"}],"urls":[{"id":36415044,"url":"https://academic.oup.com/cei/article-pdf/136/1/49/42145853/j.1365-2249.2004.02418.x.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="110530296"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons"><img alt="Research paper thumbnail of Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons" class="work-thumbnail" src="https://attachments.academia-assets.com/108319749/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons">Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons</a></div><div class="wp-workCard_item"><span>Acta veterinaria</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="05495a34eb9b648a08ad7eaf7854e8d8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108319749,"asset_id":110530296,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="110530296"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="110530296"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 110530296; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=110530296]").text(description); $(".js-view-count[data-work-id=110530296]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 110530296; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='110530296']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 110530296, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "05495a34eb9b648a08ad7eaf7854e8d8" } } $('.js-work-strip[data-work-id=110530296]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":110530296,"title":"Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons","translated_title":"","metadata":{"publisher":"National Library of Serbia","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Acta veterinaria"},"translated_abstract":null,"internal_url":"https://www.academia.edu/110530296/Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons","translated_internal_url":"","created_at":"2023-12-04T04:15:49.124-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108319749,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319749/thumbnails/1.jpg","file_name":"0567-83151201017M.pdf","download_url":"https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_and_appearance_of_multinuclear.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319749/0567-83151201017M-libre.pdf?1701696010=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_and_appearance_of_multinuclear.pdf\u0026Expires=1732395759\u0026Signature=camGRtE4JNv-L82E2k-80zavTtaaNMqtytCHkiz1t~qVncEBZV57F~h8Q4N~UaviqRpJM9EpdgDbpxpWFMp5h9xZxR10HnqKlw4A603b77lmTmChQKPjEkkeYrmslyIjd4yv401-akTPIxG4krLrOpsEXQ4501B5hTC9aBxVGAoB5py61dCHWBhmcPQrr5mz3A4V61LGNlhGOlpCJrey~pxrXdNAIiApr~UiiW94ABxpDcUEmPXNnGGq3JUtKxGnxkR~0c1-OeRLHyvmfTdOvpaTIQG3zxQTsx4cRqsdchBdR4o7WG-RlsmYsQFahrHHgxQDwMF3RJmxKns2fDNVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptosis_and_appearance_of_multinuclear_C6_glioma_cells_after_treatment_by_microtubule_poisons","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":108319749,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108319749/thumbnails/1.jpg","file_name":"0567-83151201017M.pdf","download_url":"https://www.academia.edu/attachments/108319749/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptosis_and_appearance_of_multinuclear.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108319749/0567-83151201017M-libre.pdf?1701696010=\u0026response-content-disposition=attachment%3B+filename%3DApoptosis_and_appearance_of_multinuclear.pdf\u0026Expires=1732395759\u0026Signature=camGRtE4JNv-L82E2k-80zavTtaaNMqtytCHkiz1t~qVncEBZV57F~h8Q4N~UaviqRpJM9EpdgDbpxpWFMp5h9xZxR10HnqKlw4A603b77lmTmChQKPjEkkeYrmslyIjd4yv401-akTPIxG4krLrOpsEXQ4501B5hTC9aBxVGAoB5py61dCHWBhmcPQrr5mz3A4V61LGNlhGOlpCJrey~pxrXdNAIiApr~UiiW94ABxpDcUEmPXNnGGq3JUtKxGnxkR~0c1-OeRLHyvmfTdOvpaTIQG3zxQTsx4cRqsdchBdR4o7WG-RlsmYsQFahrHHgxQDwMF3RJmxKns2fDNVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":55267,"name":"Mitosis","url":"https://www.academia.edu/Documents/in/Mitosis"},{"id":76383,"name":"Glioma","url":"https://www.academia.edu/Documents/in/Glioma"},{"id":138126,"name":"Microtubule Dynamics","url":"https://www.academia.edu/Documents/in/Microtubule_Dynamics"},{"id":168351,"name":"Paclitaxel","url":"https://www.academia.edu/Documents/in/Paclitaxel"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712699"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice"><img alt="Research paper thumbnail of Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice">Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice</a></div><div class="wp-workCard_item"><span>Ultrastructural Pathology</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712699"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712699"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712699; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712699]").text(description); $(".js-view-count[data-work-id=95712699]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712699; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712699']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712699, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712699]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712699,"title":"Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice","translated_title":"","metadata":{"publisher":"Informa UK Limited","publication_name":"Ultrastructural Pathology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712699/Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice","translated_internal_url":"","created_at":"2023-01-25T23:44:59.453-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Effects_of_metformin_and_simvastatin_treatment_on_ultrastructural_features_of_liver_macrophages_in_HFD_mice","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":473650,"name":"ultrastructural Pathology","url":"https://www.academia.edu/Documents/in/ultrastructural_Pathology"}],"urls":[{"id":28403234,"url":"https://www.tandfonline.com/doi/pdf/10.1080/01913123.2022.2156639"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712698"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat"><img alt="Research paper thumbnail of Appearance of melanocytes in the pineal gland of the mutant Gunn rat" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat">Appearance of melanocytes in the pineal gland of the mutant Gunn rat</a></div><div class="wp-workCard_item"><span>Medical Science Research</span><span>, 1992</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712698"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712698"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712698; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712698]").text(description); $(".js-view-count[data-work-id=95712698]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712698; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712698']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712698, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712698]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712698,"title":"Appearance of melanocytes in the pineal gland of the mutant Gunn rat","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1992,"errors":{}},"publication_name":"Medical Science Research"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712698/Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat","translated_internal_url":"","created_at":"2023-01-25T23:44:59.346-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Appearance_of_melanocytes_in_the_pineal_gland_of_the_mutant_Gunn_rat","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":159233,"name":"Medical Science","url":"https://www.academia.edu/Documents/in/Medical_Science"},{"id":613283,"name":"Pineal Gland","url":"https://www.academia.edu/Documents/in/Pineal_Gland"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712697"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients"><img alt="Research paper thumbnail of Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients" class="work-thumbnail" src="https://attachments.academia-assets.com/97819319/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients">Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients</a></div><div class="wp-workCard_item"><span>Tissue and Cell</span><span>, 2018</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b42da3bfe2aee6f1c77b7e6628ae3013" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":97819319,"asset_id":95712697,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712697"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712697"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712697; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712697]").text(description); $(".js-view-count[data-work-id=95712697]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712697; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712697']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712697, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b42da3bfe2aee6f1c77b7e6628ae3013" } } $('.js-work-strip[data-work-id=95712697]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712697,"title":"Unusual shape and structure of lymphocyte nuclei is linked to hyperglycemia in type 2 diabetes patients","translated_title":"","metadata":{"publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2018,"errors":{}},"publication_name":"Tissue and Cell"},"translated_abstract":null,"internal_url":"https://www.academia.edu/95712697/Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients","translated_internal_url":"","created_at":"2023-01-25T23:44:59.175-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":97819319,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/97819319/thumbnails/1.jpg","file_name":"j.tice.2018.04.00520230126-1-li69r4.pdf","download_url":"https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Unusual_shape_and_structure_of_lymphocyt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/97819319/j.tice.2018.04.00520230126-1-li69r4-libre.pdf?1674721692=\u0026response-content-disposition=attachment%3B+filename%3DUnusual_shape_and_structure_of_lymphocyt.pdf\u0026Expires=1732395759\u0026Signature=SYx1oJLgixL2Wkhfof6wtBLsESymBTfGW9x1v6aSk62f~QP5huuvKRMY1Tc7b-tdeNG9XXWwjmDymGYDTP9uU0f~zbah6uQBCvvd7NFIwmJ2ij27gHRAMNjBzRsD0Z5pe-8dbWB7HUnGZnIMYaURjVNBrA9SArzi9h~i3iH480V3MoAmQIUxigqHWPHg4s15LupBHVzhVHDrwT-s89oxbfjJBpG1JWSkaAZpLrxEtQ~fSu8JeI4r7BuQ2JZP2OAhj9XTg7ODsx7LRRsdk8k2HesDt9uBbnUMLBp9t6uhZWmLUCVGO0F8PmdGs~A3lDxTDFqUZqzsX47rRsETlhLWnA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Unusual_shape_and_structure_of_lymphocyte_nuclei_is_linked_to_hyperglycemia_in_type_2_diabetes_patients","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":97819319,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/97819319/thumbnails/1.jpg","file_name":"j.tice.2018.04.00520230126-1-li69r4.pdf","download_url":"https://www.academia.edu/attachments/97819319/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE1OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Unusual_shape_and_structure_of_lymphocyt.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/97819319/j.tice.2018.04.00520230126-1-li69r4-libre.pdf?1674721692=\u0026response-content-disposition=attachment%3B+filename%3DUnusual_shape_and_structure_of_lymphocyt.pdf\u0026Expires=1732395759\u0026Signature=SYx1oJLgixL2Wkhfof6wtBLsESymBTfGW9x1v6aSk62f~QP5huuvKRMY1Tc7b-tdeNG9XXWwjmDymGYDTP9uU0f~zbah6uQBCvvd7NFIwmJ2ij27gHRAMNjBzRsD0Z5pe-8dbWB7HUnGZnIMYaURjVNBrA9SArzi9h~i3iH480V3MoAmQIUxigqHWPHg4s15LupBHVzhVHDrwT-s89oxbfjJBpG1JWSkaAZpLrxEtQ~fSu8JeI4r7BuQ2JZP2OAhj9XTg7ODsx7LRRsdk8k2HesDt9uBbnUMLBp9t6uhZWmLUCVGO0F8PmdGs~A3lDxTDFqUZqzsX47rRsETlhLWnA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":23243,"name":"Type 2 Diabetes","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":65390,"name":"Internal Medicine","url":"https://www.academia.edu/Documents/in/Internal_Medicine"},{"id":71297,"name":"Metformin","url":"https://www.academia.edu/Documents/in/Metformin"},{"id":71489,"name":"Hyperinsulinemia","url":"https://www.academia.edu/Documents/in/Hyperinsulinemia"},{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus"},{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology"},{"id":238813,"name":"Chromatin","url":"https://www.academia.edu/Documents/in/Chromatin"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"}],"urls":[{"id":28403233,"url":"https://api.elsevier.com/content/article/PII:S0040816618300880?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="95712696"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation"><img alt="Research paper thumbnail of The acidophilic nature of neuronal Golgi impregnation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation">The acidophilic nature of neuronal Golgi impregnation</a></div><div class="wp-workCard_item"><span>Acta Histochemica</span><span>, 1998</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="95712696"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="95712696"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 95712696; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=95712696]").text(description); $(".js-view-count[data-work-id=95712696]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 95712696; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='95712696']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 95712696, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=95712696]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":95712696,"title":"The acidophilic nature of neuronal Golgi impregnation","translated_title":"","metadata":{"abstract":"The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.","publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":1998,"errors":{}},"publication_name":"Acta Histochemica"},"translated_abstract":"The mechanisms of Golgi impregnation of neurons has remained enigmatic for decades. Recently, it was suggested that divalent (di)chromate anions play a role in the Golgi impregnation process. Therefore, we incubated slices of (para)formaldehyde-fixed rat brain tissue in solutions of potassium (di)chromate, phosphate, chloride or nitrate at pH 6 or 7. Slices were then immersed in solutions of silver nitrate and processed for light microscopical analysis. At pH 6, dichromate probes resulted in dense and homogeneous impregnation of neuronal cytoplasm (typical impregnation). At pH 7, chromate probes showed solely partial cytoplasmic and heavy nuclear-region neuron impregnation (atypical impregnation). Phosphate probes at pH 6 resulted in typical impregnation, whereas at pH 7 phosphate probes gave atypical impregnation. Both at pH 6 and 7, chloride and nitrate probes did not yield any Golgi impregnation. These findings confirmed the pH-dependence of silver-chromate Golgi impregnation as well as the correctness of corresponding acidic silver-phosphate impregnation. Our study revealed a previously unknown, strong anion-dependence of Golgi impregnation, suggesting that hydrogenated monovalent anions are carriers of the neuron impregnation.","internal_url":"https://www.academia.edu/95712696/The_acidophilic_nature_of_neuronal_Golgi_impregnation","translated_internal_url":"","created_at":"2023-01-25T23:44:58.932-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_acidophilic_nature_of_neuronal_Golgi_impregnation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":530,"name":"Inorganic Chemistry","url":"https://www.academia.edu/Documents/in/Inorganic_Chemistry"},{"id":21466,"name":"Polymers","url":"https://www.academia.edu/Documents/in/Polymers"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":26931,"name":"Nuclear Chemistry","url":"https://www.academia.edu/Documents/in/Nuclear_Chemistry"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":122402,"name":"Nitrates","url":"https://www.academia.edu/Documents/in/Nitrates"},{"id":162982,"name":"Chloride","url":"https://www.academia.edu/Documents/in/Chloride"},{"id":193974,"name":"Neurons","url":"https://www.academia.edu/Documents/in/Neurons"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":541785,"name":"Phosphates","url":"https://www.academia.edu/Documents/in/Phosphates"},{"id":819116,"name":"Formaldehyde","url":"https://www.academia.edu/Documents/in/Formaldehyde"},{"id":843400,"name":"Phosphate","url":"https://www.academia.edu/Documents/in/Phosphate"},{"id":979301,"name":"Golgi Apparatus","url":"https://www.academia.edu/Documents/in/Golgi_Apparatus"},{"id":1295914,"name":"Potassium Chloride","url":"https://www.academia.edu/Documents/in/Potassium_Chloride"},{"id":1436040,"name":"Potassium Compounds","url":"https://www.academia.edu/Documents/in/Potassium_Compounds"},{"id":2550937,"name":"Molecular probes","url":"https://www.academia.edu/Documents/in/Molecular_probes"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"}],"urls":[{"id":28403232,"url":"https://api.elsevier.com/content/article/PII:S0065128198800299?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="89649472"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells"><img alt="Research paper thumbnail of Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells" class="work-thumbnail" src="https://attachments.academia-assets.com/93409788/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells">Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells</a></div><div class="wp-workCard_item"><span>Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="60d052b5628c78134051d8840ce54f24" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":93409788,"asset_id":89649472,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="89649472"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="89649472"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 89649472; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=89649472]").text(description); $(".js-view-count[data-work-id=89649472]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 89649472; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='89649472']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 89649472, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "60d052b5628c78134051d8840ce54f24" } } $('.js-work-strip[data-work-id=89649472]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":89649472,"title":"Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells","translated_title":"","metadata":{"publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"},"translated_abstract":null,"internal_url":"https://www.academia.edu/89649472/Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells","translated_internal_url":"","created_at":"2022-10-31T15:14:43.821-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":93409788,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93409788/thumbnails/1.jpg","file_name":"aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__.pdf","download_url":"https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Autophagy_dependent_and_independent_invo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93409788/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__-libre.pdf?1667254849=\u0026response-content-disposition=attachment%3B+filename%3DAutophagy_dependent_and_independent_invo.pdf\u0026Expires=1732395760\u0026Signature=FhanA-raoaiAEt37u0aaPZcktBQ72aYoEX4H-MteC~H7msCBAjJn0F77zZ9VdFS4uvFnQ4yBoi58hxRBNR1HkprfZDzrnKZcpFfuW8GGJCZxPpQQsyVW8H0wLMtlsBda8lAPL85H28o1k5V9ZYDvi7THam8JgpDIB19tByR8aIY5WJ4wlSsEhPLBkOq4~K2V16n9ZnSR66gHUp6gEb90tUf1PRvxuEnSyzH1avpF3FdvknJlAjlheg-xVZ5~EUCsI5gDQ1KBru9vn31LAQ24jXt~YJMi7CIRtJ4pPKB1vM84rayeSYs5jwelfTV8-5LGV-AytNyakcJYW6s1Yvb~Dg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Autophagy_dependent_and_independent_involvement_of_AMP_activated_protein_kinase_in_6_hydroxydopamine_toxicity_to_SH_SY5Y_neuroblastoma_cells","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":93409788,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/93409788/thumbnails/1.jpg","file_name":"aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__.pdf","download_url":"https://www.academia.edu/attachments/93409788/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Autophagy_dependent_and_independent_invo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/93409788/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDkyNTQ0MzkxMjAwMTkyNQ__-libre.pdf?1667254849=\u0026response-content-disposition=attachment%3B+filename%3DAutophagy_dependent_and_independent_invo.pdf\u0026Expires=1732395760\u0026Signature=FhanA-raoaiAEt37u0aaPZcktBQ72aYoEX4H-MteC~H7msCBAjJn0F77zZ9VdFS4uvFnQ4yBoi58hxRBNR1HkprfZDzrnKZcpFfuW8GGJCZxPpQQsyVW8H0wLMtlsBda8lAPL85H28o1k5V9ZYDvi7THam8JgpDIB19tByR8aIY5WJ4wlSsEhPLBkOq4~K2V16n9ZnSR66gHUp6gEb90tUf1PRvxuEnSyzH1avpF3FdvknJlAjlheg-xVZ5~EUCsI5gDQ1KBru9vn31LAQ24jXt~YJMi7CIRtJ4pPKB1vM84rayeSYs5jwelfTV8-5LGV-AytNyakcJYW6s1Yvb~Dg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":14076,"name":"Transmission Electron Microscopy","url":"https://www.academia.edu/Documents/in/Transmission_Electron_Microscopy"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":118582,"name":"Physical sciences","url":"https://www.academia.edu/Documents/in/Physical_sciences"},{"id":172083,"name":"Phosphorylation","url":"https://www.academia.edu/Documents/in/Phosphorylation"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":256805,"name":"Neuroblastoma","url":"https://www.academia.edu/Documents/in/Neuroblastoma"},{"id":550730,"name":"6-Hydroxydopamine","url":"https://www.academia.edu/Documents/in/6-Hydroxydopamine"},{"id":788681,"name":"N-Acetylcysteine","url":"https://www.academia.edu/Documents/in/N-Acetylcysteine"},{"id":1150115,"name":"Sirolimus","url":"https://www.academia.edu/Documents/in/Sirolimus"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1763968,"name":"Gene Expression Regulation","url":"https://www.academia.edu/Documents/in/Gene_Expression_Regulation"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics"},{"id":4061411,"name":"acetylcysteine","url":"https://www.academia.edu/Documents/in/acetylcysteine"}],"urls":[{"id":25372696,"url":"https://api.elsevier.com/content/article/PII:S0925443912001925?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84852975"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_"><img alt="Research paper thumbnail of Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]" class="work-thumbnail" src="https://attachments.academia-assets.com/89736593/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_">Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="48dd8af7069e19cf9bc8a69311eec7a4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89736593,"asset_id":84852975,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84852975"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84852975"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84852975; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84852975]").text(description); $(".js-view-count[data-work-id=84852975]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84852975; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84852975']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84852975, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "48dd8af7069e19cf9bc8a69311eec7a4" } } $('.js-work-strip[data-work-id=84852975]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84852975,"title":"Anion-dependent Nature Of Neuronal Golgi Impregnation [B.D. Stefanovic et al, Acta Histochemica 100(2), 217-227, 1998]","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2013,"errors":{}}},"translated_abstract":null,"internal_url":"https://www.academia.edu/84852975/Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_","translated_internal_url":"","created_at":"2022-08-15T23:32:00.662-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89736593,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89736593/thumbnails/1.jpg","file_name":"70eef44557b66d0fc3861a04fed16754c546.pdf","download_url":"https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Anion_dependent_Nature_Of_Neuronal_Golgi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89736593/70eef44557b66d0fc3861a04fed16754c546-libre.pdf?1660638903=\u0026response-content-disposition=attachment%3B+filename%3DAnion_dependent_Nature_Of_Neuronal_Golgi.pdf\u0026Expires=1732395760\u0026Signature=RxxO1as6wS5rihAByH01iJlo15cOEiA2HCcJQNy0lcorJlhXoJS3WP~jAFdCEtw2A-~Bn6NXN5xAKNYXKpPjNebKRKK1SOwq-b4y1l2JLnzEODWVpF0dRNQk5jhb8NqaVMOO202Xx81HW6L7wnJZfnlAYu7dDeMyzUlSBQttoCYk~SWiC3nrIdOXumvyr4SAAMxJNPmAA-D1g953~3fvJo6JLO7GSmnzG8XCJKti6s1HhA5M61rYj77zTcOpZLbu3fay-k~gv~vuKESE34yLOUs5VmGrw7DPVaLMnqax3XYygiGTWojLmrzeRuALKhPeeoUDCk27zeDPae5-B8E1VA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Anion_dependent_Nature_Of_Neuronal_Golgi_Impregnation_B_D_Stefanovic_et_al_Acta_Histochemica_100_2_217_227_1998_","translated_slug":"","page_count":11,"language":"id","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":89736593,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89736593/thumbnails/1.jpg","file_name":"70eef44557b66d0fc3861a04fed16754c546.pdf","download_url":"https://www.academia.edu/attachments/89736593/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Anion_dependent_Nature_Of_Neuronal_Golgi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89736593/70eef44557b66d0fc3861a04fed16754c546-libre.pdf?1660638903=\u0026response-content-disposition=attachment%3B+filename%3DAnion_dependent_Nature_Of_Neuronal_Golgi.pdf\u0026Expires=1732395760\u0026Signature=RxxO1as6wS5rihAByH01iJlo15cOEiA2HCcJQNy0lcorJlhXoJS3WP~jAFdCEtw2A-~Bn6NXN5xAKNYXKpPjNebKRKK1SOwq-b4y1l2JLnzEODWVpF0dRNQk5jhb8NqaVMOO202Xx81HW6L7wnJZfnlAYu7dDeMyzUlSBQttoCYk~SWiC3nrIdOXumvyr4SAAMxJNPmAA-D1g953~3fvJo6JLO7GSmnzG8XCJKti6s1HhA5M61rYj77zTcOpZLbu3fay-k~gv~vuKESE34yLOUs5VmGrw7DPVaLMnqax3XYygiGTWojLmrzeRuALKhPeeoUDCk27zeDPae5-B8E1VA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":979301,"name":"Golgi Apparatus","url":"https://www.academia.edu/Documents/in/Golgi_Apparatus"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="79985040"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy"><img alt="Research paper thumbnail of Guidelines for the use and interpretation of assays for monitoring autophagy" class="work-thumbnail" src="https://attachments.academia-assets.com/86517133/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy">Guidelines for the use and interpretation of assays for monitoring autophagy</a></div><div class="wp-workCard_item"><span>Autophagy</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="95cd2707b8d89aede3ec4f57ef65b1d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":86517133,"asset_id":79985040,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="79985040"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="79985040"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 79985040; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=79985040]").text(description); $(".js-view-count[data-work-id=79985040]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 79985040; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='79985040']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 79985040, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "95cd2707b8d89aede3ec4f57ef65b1d4" } } $('.js-work-strip[data-work-id=79985040]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":79985040,"title":"Guidelines for the use and interpretation of assays for monitoring autophagy","translated_title":"","metadata":{"publisher":"Informa UK Limited","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Autophagy"},"translated_abstract":null,"internal_url":"https://www.academia.edu/79985040/Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy","translated_internal_url":"","created_at":"2022-05-26T09:26:32.354-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":86517133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/86517133/thumbnails/1.jpg","file_name":"2012AUTO0036.pdf","download_url":"https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Guidelines_for_the_use_and_interpretatio.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/86517133/2012AUTO0036-libre.pdf?1653583098=\u0026response-content-disposition=attachment%3B+filename%3DGuidelines_for_the_use_and_interpretatio.pdf\u0026Expires=1732395760\u0026Signature=bCuzObsNGSfQhTYbEJ6MCefBwbjBJ3GGMy-15Kwcomc5FS2~tlWC8zIIjMtAqeSwMLsEAcs1kVDtIKWVMcFvw540rUmMZAtoQO5jFnGPoXlxsfCW-659fHGg-WjqEZAVa5kaKUCF11zmr~4EMod3M~b2LYtzqvokbB2-YgHLxOxw5QRymODeKHXqmN3LiGbJ9a72JSNAjjzJXMLP6konzW7-QZET4iFJ0fQBqdlTnybu0P75qzpg6iUDVdifIgjUoXES33umyNscFbsRmFqkFGQJ0gI8wv0MchAHOa43dkW0waVFedZgR1ddv5KV3RQP8nO2orJIEwetLNAxh3aVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Guidelines_for_the_use_and_interpretation_of_assays_for_monitoring_autophagy","translated_slug":"","page_count":100,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":86517133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/86517133/thumbnails/1.jpg","file_name":"2012AUTO0036.pdf","download_url":"https://www.academia.edu/attachments/86517133/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Guidelines_for_the_use_and_interpretatio.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/86517133/2012AUTO0036-libre.pdf?1653583098=\u0026response-content-disposition=attachment%3B+filename%3DGuidelines_for_the_use_and_interpretatio.pdf\u0026Expires=1732395760\u0026Signature=bCuzObsNGSfQhTYbEJ6MCefBwbjBJ3GGMy-15Kwcomc5FS2~tlWC8zIIjMtAqeSwMLsEAcs1kVDtIKWVMcFvw540rUmMZAtoQO5jFnGPoXlxsfCW-659fHGg-WjqEZAVa5kaKUCF11zmr~4EMod3M~b2LYtzqvokbB2-YgHLxOxw5QRymODeKHXqmN3LiGbJ9a72JSNAjjzJXMLP6konzW7-QZET4iFJ0fQBqdlTnybu0P75qzpg6iUDVdifIgjUoXES33umyNscFbsRmFqkFGQJ0gI8wv0MchAHOa43dkW0waVFedZgR1ddv5KV3RQP8nO2orJIEwetLNAxh3aVLQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry"},{"id":7700,"name":"Fluorescence Microscopy","url":"https://www.academia.edu/Documents/in/Fluorescence_Microscopy"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":13848,"name":"Deep Ecology","url":"https://www.academia.edu/Documents/in/Deep_Ecology"},{"id":14406,"name":"Health","url":"https://www.academia.edu/Documents/in/Health"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":37782,"name":"Cell Culture","url":"https://www.academia.edu/Documents/in/Cell_Culture"},{"id":37783,"name":"Assay Development","url":"https://www.academia.edu/Documents/in/Assay_Development"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":72527,"name":"Ch","url":"https://www.academia.edu/Documents/in/Ch"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals"},{"id":112576,"name":"Cell Death","url":"https://www.academia.edu/Documents/in/Cell_Death"},{"id":136787,"name":"ER stress","url":"https://www.academia.edu/Documents/in/ER_stress"},{"id":771990,"name":"Eukaryotic Cells","url":"https://www.academia.edu/Documents/in/Eukaryotic_Cells"},{"id":833228,"name":"Human Disease","url":"https://www.academia.edu/Documents/in/Human_Disease"},{"id":1109769,"name":"Biological Assay","url":"https://www.academia.edu/Documents/in/Biological_Assay"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"}],"urls":[{"id":20803294,"url":"http://www.tandfonline.com/doi/pdf/10.4161/auto.19496"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="73640096"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced"><img alt="Research paper thumbnail of Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced" class="work-thumbnail" src="https://attachments.academia-assets.com/82082814/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced">Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study investigated the role of autophagy, a cellular self-digestion process, in the c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b2ce32d59c987881a9f466e9a5e0bd99" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":82082814,"asset_id":73640096,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="73640096"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="73640096"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 73640096; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=73640096]").text(description); $(".js-view-count[data-work-id=73640096]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 73640096; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='73640096']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 73640096, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b2ce32d59c987881a9f466e9a5e0bd99" } } $('.js-work-strip[data-work-id=73640096]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":73640096,"title":"Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced","translated_title":"","metadata":{"abstract":"The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...","publication_date":{"day":null,"month":null,"year":2016,"errors":{}}},"translated_abstract":"The present study investigated the role of autophagy, a cellular self-digestion process, in the cytotoxicity of antileukemic drug cytarabine towards human leukemic cell lines (REH, HL-60, MOLT-4) and peripheral blood mononuclear cells from leukemic patients. The induction of autophagy was confirmed by acridine orange staining of intracellular acidic vesicles, electron microscopy visualization of autophagic vacuoles, as well as by the increase in autophagic proteolysis and autophagic flux, demonstrated by immunoblot analysis of p62 downregulation and LC3-I conversion to autophagosome-associated LC3-II in the presence of proteolysis inhibitors, respectively. Moreover, the expression of autophagy-related genes Atg4, Atg5 and Atg7 was stimulated by cytarabine in REH cells. Cytarabine reduced the phosphorylation of the major negative regulator of autophagy, mammalian target of rapamycin (mTOR), and its downstream target p70S6 kinase in REH cells, which was associated with downregulation ...","internal_url":"https://www.academia.edu/73640096/Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced","translated_internal_url":"","created_at":"2022-03-12T23:23:11.041-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":82082814,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/82082814/thumbnails/1.jpg","file_name":"asset.pdf","download_url":"https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inhibition_of_mTOR_Dependent_Autophagy_S.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/82082814/asset-libre.pdf?1647158805=\u0026response-content-disposition=attachment%3B+filename%3DInhibition_of_mTOR_Dependent_Autophagy_S.pdf\u0026Expires=1732395760\u0026Signature=TOrXy1Xz-IgkYZDidVznemsdjJJJJkx0l1mh1gkQD3yDqZ~wpW7Y39Bjd7XbVvH4YoDX7UwvThOqrHfwhgd7YPH~uNGM1o5R7mJbiEc2AWpX8o4HqvPBv7L-Em1zMR~rwWgEzFVUxUx1n4OJS40CEvdZIEo0lgF39vjNsNmg3veuC489LwCKa8LrdEjnh6nz~buaH9K9yS977bicnRdfLZ7cKOuy1NBls7Q9C2sIgAtyTZl05IYy8NvLoXNvD9Q2oF148zfpgnA5UBRgFVP3H8KPjVgzKXh9vT4t440J1328vhtE0I433b3etCQXiRU~hlOO9PeoJvLbckoOiEbFWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Inhibition_of_mTOR_Dependent_Autophagy_Sensitizes_Leukemic_Cells_to_Cytarabine_Induced","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[{"id":82082814,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/82082814/thumbnails/1.jpg","file_name":"asset.pdf","download_url":"https://www.academia.edu/attachments/82082814/download_file?st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM5MjE2MCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Inhibition_of_mTOR_Dependent_Autophagy_S.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/82082814/asset-libre.pdf?1647158805=\u0026response-content-disposition=attachment%3B+filename%3DInhibition_of_mTOR_Dependent_Autophagy_S.pdf\u0026Expires=1732395760\u0026Signature=TOrXy1Xz-IgkYZDidVznemsdjJJJJkx0l1mh1gkQD3yDqZ~wpW7Y39Bjd7XbVvH4YoDX7UwvThOqrHfwhgd7YPH~uNGM1o5R7mJbiEc2AWpX8o4HqvPBv7L-Em1zMR~rwWgEzFVUxUx1n4OJS40CEvdZIEo0lgF39vjNsNmg3veuC489LwCKa8LrdEjnh6nz~buaH9K9yS977bicnRdfLZ7cKOuy1NBls7Q9C2sIgAtyTZl05IYy8NvLoXNvD9Q2oF148zfpgnA5UBRgFVP3H8KPjVgzKXh9vT4t440J1328vhtE0I433b3etCQXiRU~hlOO9PeoJvLbckoOiEbFWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia"},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction"},{"id":51121,"name":"RNA interference","url":"https://www.academia.edu/Documents/in/RNA_interference"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"}],"urls":[{"id":18462112,"url":"http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.937.1204\u0026rep=rep1\u0026type=pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="64199069"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells"><img alt="Research paper thumbnail of Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells">Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells</a></div><div class="wp-workCard_item"><span>PLOS ONE</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="64199069"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="64199069"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 64199069; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=64199069]").text(description); $(".js-view-count[data-work-id=64199069]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 64199069; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='64199069']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 64199069, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=64199069]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":64199069,"title":"Cytarabine induces Atg expression, inhibits mTOR and modulates Akt/ERK signaling in REH cells","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"PLOS ONE"},"translated_abstract":null,"internal_url":"https://www.academia.edu/64199069/Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells","translated_internal_url":"","created_at":"2021-12-14T23:24:55.175-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15465688,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Cytarabine_induces_Atg_expression_inhibits_mTOR_and_modulates_Akt_ERK_signaling_in_REH_cells","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":15465688,"first_name":"Vladimir","middle_initials":null,"last_name":"Bumbasirevic","page_name":"VladimirBumbasirevic","domain_name":"independent","created_at":"2014-08-21T03:06:41.524-07:00","display_name":"Vladimir Bumbasirevic","url":"https://independent.academia.edu/VladimirBumbasirevic"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/google_contacts-0dfb882d836b94dbcb4a2d123d6933fc9533eda5be911641f20b4eb428429600.js"], function() { // from javascript_helper.rb $('.js-google-connect-button').click(function(e) { e.preventDefault(); GoogleContacts.authorize_and_show_contacts(); Aedu.Dismissibles.recordClickthrough("WowProfileImportContactsPrompt"); }); $('.js-update-biography-button').click(function(e) { e.preventDefault(); Aedu.Dismissibles.recordClickthrough("UpdateUserBiographyPrompt"); $.ajax({ url: $r.api_v0_profiles_update_about_path({ subdomain_param: 'api', about: "", }), type: 'PUT', success: function(response) { location.reload(); } }); }); $('.js-work-creator-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_document_path({ source: encodeURIComponent(""), }); }); $('.js-video-upload-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_video_path({ source: encodeURIComponent(""), }); }); $('.js-do-this-later-button').click(function() { $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("WowProfileImportContactsPrompt"); }); $('.js-update-biography-do-this-later-button').click(function(){ $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("UpdateUserBiographyPrompt"); }); $('.wow-profile-mentions-upsell--close').click(function(){ $('.wow-profile-mentions-upsell--panel').hide(); Aedu.Dismissibles.recordDismissal("WowProfileMentionsUpsell"); }); $('.wow-profile-mentions-upsell--button').click(function(){ Aedu.Dismissibles.recordClickthrough("WowProfileMentionsUpsell"); }); new WowProfile.SocialRedesignUserWorks({ initialWorksOffset: 20, allWorksOffset: 20, maxSections: 1 }) }); </script> </div></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile_edit-5ea339ee107c863779f560dd7275595239fed73f1a13d279d2b599a28c0ecd33.js","https://a.academia-assets.com/assets/add_coauthor-22174b608f9cb871d03443cafa7feac496fb50d7df2d66a53f5ee3c04ba67f53.js","https://a.academia-assets.com/assets/tab-dcac0130902f0cc2d8cb403714dd47454f11fc6fb0e99ae6a0827b06613abc20.js","https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js"], function() { // from javascript_helper.rb window.ae = window.ae || {}; window.ae.WowProfile = window.ae.WowProfile || {}; if(Aedu.User.current && Aedu.User.current.id === $viewedUser.id) { window.ae.WowProfile.current_user_edit = {}; new WowProfileEdit.EditUploadView({ el: '.js-edit-upload-button-wrapper', model: window.$current_user, }); new AddCoauthor.AddCoauthorsController(); } var userInfoView = new WowProfile.SocialRedesignUserInfo({ recaptcha_key: "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB" }); WowProfile.router = new WowProfile.Router({ userInfoView: userInfoView }); Backbone.history.start({ pushState: true, root: "/" + $viewedUser.page_name }); new WowProfile.UserWorksNav() }); </script> </div> <div class="bootstrap login"><div class="modal fade login-modal" id="login-modal"><div class="login-modal-dialog modal-dialog"><div class="modal-content"><div class="modal-header"><button class="close close" data-dismiss="modal" type="button"><span aria-hidden="true">×</span><span class="sr-only">Close</span></button><h4 class="modal-title text-center"><strong>Log In</strong></h4></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><button class="btn btn-fb btn-lg btn-block btn-v-center-content" id="login-facebook-oauth-button"><svg style="float: left; width: 19px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="facebook-square" class="svg-inline--fa fa-facebook-square fa-w-14" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path fill="currentColor" d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg><small><strong>Log in</strong> with <strong>Facebook</strong></small></button><br /><button class="btn btn-google btn-lg btn-block btn-v-center-content" id="login-google-oauth-button"><svg style="float: left; width: 22px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="google-plus" class="svg-inline--fa fa-google-plus fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256,8C119.1,8,8,119.1,8,256S119.1,504,256,504,504,392.9,504,256,392.9,8,256,8ZM185.3,380a124,124,0,0,1,0-248c31.3,0,60.1,11,83,32.3l-33.6,32.6c-13.2-12.9-31.3-19.1-49.4-19.1-42.9,0-77.2,35.5-77.2,78.1S142.3,334,185.3,334c32.6,0,64.9-19.1,70.1-53.3H185.3V238.1H302.2a109.2,109.2,0,0,1,1.9,20.7c0,70.8-47.5,121.2-118.8,121.2ZM415.5,273.8v35.5H380V273.8H344.5V238.3H380V202.8h35.5v35.5h35.2v35.5Z"></path></svg><small><strong>Log in</strong> with <strong>Google</strong></small></button><br /><style type="text/css">.sign-in-with-apple-button { width: 100%; height: 52px; border-radius: 3px; border: 1px solid black; cursor: pointer; }</style><script src="https://appleid.cdn-apple.com/appleauth/static/jsapi/appleid/1/en_US/appleid.auth.js" type="text/javascript"></script><div class="sign-in-with-apple-button" data-border="false" data-color="white" id="appleid-signin"><span   ="Sign Up with Apple" class="u-fs11"></span></div><script>AppleID.auth.init({ clientId: 'edu.academia.applesignon', scope: 'name email', redirectURI: 'https://www.academia.edu/sessions', state: "07dacc2bf38d98ac2bbcd7bd8e3474437480598a208a7d4922c9e4f9ae3f9199", });</script><script>// Hacky way of checking if on fast loswp if (window.loswp == null) { (function() { const Google = window?.Aedu?.Auth?.OauthButton?.Login?.Google; const Facebook = window?.Aedu?.Auth?.OauthButton?.Login?.Facebook; if (Google) { new Google({ el: '#login-google-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } if (Facebook) { new Facebook({ el: '#login-facebook-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } })(); }</script></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><div class="hr-heading login-hr-heading"><span class="hr-heading-text">or</span></div></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><form class="js-login-form" action="https://www.academia.edu/sessions" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="qfFXHhpmF0W6eqFHWRoGSoxWBVp2XmktBpItKTAYdhBmQXPmf+z+Tg8jqNXSJRebS/jRd1fmF2qlX6gzzeSxeA==" autocomplete="off" /><div class="form-group"><label class="control-label" for="login-modal-email-input" style="font-size: 14px;">Email</label><input class="form-control" id="login-modal-email-input" name="login" type="email" /></div><div class="form-group"><label class="control-label" for="login-modal-password-input" style="font-size: 14px;">Password</label><input class="form-control" id="login-modal-password-input" name="password" type="password" /></div><input type="hidden" name="post_login_redirect_url" id="post_login_redirect_url" value="https://independent.academia.edu/VladimirBumbasirevic" autocomplete="off" /><div class="checkbox"><label><input type="checkbox" name="remember_me" id="remember_me" value="1" checked="checked" /><small style="font-size: 12px; margin-top: 2px; display: inline-block;">Remember me on this computer</small></label></div><br><input type="submit" name="commit" value="Log In" class="btn btn-primary btn-block btn-lg js-login-submit" data-disable-with="Log In" /></br></form><script>typeof window?.Aedu?.recaptchaManagedForm === 'function' && window.Aedu.recaptchaManagedForm( document.querySelector('.js-login-form'), document.querySelector('.js-login-submit') );</script><small style="font-size: 12px;"><br />or <a data-target="#login-modal-reset-password-container" data-toggle="collapse" href="javascript:void(0)">reset password</a></small><div class="collapse" id="login-modal-reset-password-container"><br /><div class="well margin-0x"><form class="js-password-reset-form" action="https://www.academia.edu/reset_password" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="VdARY2/G08di3C6L3+Q0hHg+ADCKur1u6si2mJxc/I2aYDWbCkw6zNeFJxlU2yVVv5DUHasCwylJBTOCYaA75Q==" autocomplete="off" /><p>Enter the email address you signed up with and we'll email you a reset link.</p><div class="form-group"><input class="form-control" name="email" type="email" /></div><script src="https://recaptcha.net/recaptcha/api.js" async defer></script> <script> var invisibleRecaptchaSubmit = function () { var closestForm = function (ele) { var curEle = ele.parentNode; while (curEle.nodeName !== 'FORM' && curEle.nodeName !== 'BODY'){ curEle = curEle.parentNode; } return curEle.nodeName === 'FORM' ? curEle : null }; var eles = document.getElementsByClassName('g-recaptcha'); if (eles.length > 0) { var form = closestForm(eles[0]); if (form) { form.submit(); } } }; </script> <input type="submit" data-sitekey="6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj" data-callback="invisibleRecaptchaSubmit" class="g-recaptcha btn btn-primary btn-block" value="Email me a link" value=""/> </form></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/collapse-45805421cf446ca5adf7aaa1935b08a3a8d1d9a6cc5d91a62a2a3a00b20b3e6a.js"], function() { // from javascript_helper.rb $("#login-modal-reset-password-container").on("shown.bs.collapse", function() { $(this).find("input[type=email]").focus(); }); }); </script> </div></div></div><div class="modal-footer"><div class="text-center"><small style="font-size: 12px;">Need an account? <a rel="nofollow" href="https://www.academia.edu/signup">Click here to sign up</a></small></div></div></div></div></div></div><script>// If we are on subdomain or non-bootstrapped page, redirect to login page instead of showing modal (function(){ if (typeof $ === 'undefined') return; var host = window.location.hostname; if ((host === $domain || host === "www."+$domain) && (typeof $().modal === 'function')) { $("#nav_log_in").click(function(e) { // Don't follow the link and open the modal e.preventDefault(); $("#login-modal").on('shown.bs.modal', function() { $(this).find("#login-modal-email-input").focus() }).modal('show'); }); } })()</script> <div class="bootstrap" id="footer"><div class="footer-content clearfix text-center padding-top-7x" style="width:100%;"><ul class="footer-links-secondary footer-links-wide list-inline margin-bottom-1x"><li><a href="https://www.academia.edu/about">About</a></li><li><a href="https://www.academia.edu/press">Press</a></li><li><a rel="nofollow" href="https://medium.com/academia">Blog</a></li><li><a href="https://www.academia.edu/documents">Papers</a></li><li><a href="https://www.academia.edu/topics">Topics</a></li><li><a href="https://www.academia.edu/journals">Academia.edu Journals</a></li><li><a rel="nofollow" href="https://www.academia.edu/hiring"><svg style="width: 13px; height: 13px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg> <strong>We're Hiring!</strong></a></li><li><a rel="nofollow" href="https://support.academia.edu/"><svg style="width: 12px; height: 12px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg> <strong>Help Center</strong></a></li></ul><ul class="footer-links-tertiary list-inline margin-bottom-1x"><li class="small">Find new research papers in:</li><li class="small"><a href="https://www.academia.edu/Documents/in/Physics">Physics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Biology">Biology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Health_Sciences">Health Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Ecology">Ecology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a></li></ul></div></div><div class="DesignSystem" id="credit" style="width:100%;"><ul class="u-pl0x footer-links-legal list-inline"><li><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li>Academia ©2024</li></ul></div><script> //<![CDATA[ window.detect_gmtoffset = true; window.Academia && window.Academia.set_gmtoffset && Academia.set_gmtoffset('/gmtoffset'); //]]> </script> <div id='overlay_background'></div> <div id='bootstrap-modal-container' class='bootstrap'></div> <div id='ds-modal-container' class='bootstrap DesignSystem'></div> <div id='full-screen-modal'></div> </div> </body> </html>