<?xml version="1.0" encoding="UTF-8"?> <article key="pdf/10007358" mdate="2017-05-02 00:00:00"> <author>Laila Seada and Ashraf Ibrahim and Amjad Al Shammari</author> <title>Patterns of Malignant and Benign Breast Lesions in Hail Region A Retrospective Study at King Khalid Hospital</title> <pages>367 - 370</pages> <year>2017</year> <volume>11</volume> <number>6</number> <journal>International Journal of Medical and Health Sciences</journal> <ee>https://publications.waset.org/pdf/10007358</ee> <url>https://publications.waset.org/vol/126</url> <publisher>World Academy of Science, Engineering and Technology</publisher> <abstract>Background and Objectives Breast carcinoma is the most common cancer of females in Hail region, accounting for 31 of all diagnosed cancer cases followed by thyroid carcinoma (25) and colorectal carcinoma (13). Methods In the present retrospective study, all cases of breast lesions received at the histopathology department in King Khalid Hospital, Hail, during the period from May 2011 to April 2016 have been retrieved from department files. For all cases, a trucut biopsy, lumpectomy, or modified radical mastectomy was available for histopathologic diagnosis, while 105140 (75) had, as well, preoperative fine needle aspirates (FNA). Results 49 cases out of 140 (35) breast lesions were carcinomas 4449 (89.75) was invasive ductal, 249(4.1) invasive lobular carcinomas, 149(2.05) intracystic low grade papillary carcinoma and 249 (4.1) ductal carcinoma in situ (DCIS). Mean age for malignant cases was 45.06 (10.58) 32.6 were below the age of 40 and 30.6 below 50 years, 18.3 below 60 and 16.3 below 70 years. For the benign group, mean age was 32.52 (10.5) years. Benign lesions were in order of frequency 34 fibroadenomas, 14 fibrocystic disease, 12 chronic mastitis, five granulomatous mastitis, three intraductal papillomas, and three benign phyllodes tumor. Tubular adenoma, lipoma, skin nevus, pilomatrixoma, and breast reduction specimens constituted the remaining specimens. Conclusion Breast lesions are common in our series and invasive carcinoma accounts for more than 13rd of the lumps, with 63.2 incidence in premenopausal ladies, below the age of 50 years. FNA as a noninvasive procedure, proved to be an effective tool in diagnosing both benign and malignantsuspicious breast lumps and should continue to be used as a first assessment line of palpable breast masses. </abstract> <index>Open Science Index 126, 2017</index> </article>