Mouse IL-6 Quantikine ELISA Kit, 2 Plate (M6000B): Novus Biologicals

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5.1724696046-473375462.1712005244" style="margin: 0 10px;" target="_blank"><img alt="Novus Biologicals products are now on bio-techne.com" src="https://images.novusbio.com/design/ready-to-buy-novus-products-login.png" style="height:120px; width:940px" /></a></div> </div> </div> </div> <h1>Mouse IL-6 Quantikine ELISA Kit, 2 Plate</h1> </div> <div class="clear"></div> <div> <div class="region region-content"> <div id="block-et-messages-et-messages-block" class="block block-et-messages"> <div class="content"> <span></span> </div> </div> <div id="block-system-main" class="block block-system"> <div class="content"> <div class="grid_16"><div class="ds_info float_left"><a href="#PublicationSection"><div class="sprite_pubBook_large"></div></a> <a href="#PublicationSection" class="bottom2"><span class="ctr">(659 Publications)</span></a></div><div class="ds_info float_left"> <a href="/common-name/il-6"><div class="sprite_allRelated"></div></a> <a href="/common-name/il-6" class="bottom4"><span class="ctr">See All Related</span></a> </div><div class="ds_info float_left"><a href="/reviews/M6000B"><div class="dsSprite_submitreview"></div></a> <a href="/reviews/M6000B" class="bottom4"><span class="ctr">Submit a Review</span></a></div></div></div><div class="modalWrapper" style="display:none;"> <h2>Species Glossary</h2> <hr class="customhr"/> <img src="//images.novusbio.com/design/bunny.gif" alt="Species Glossary Rabbit" style="float: right;"> <table class="modalTable"> <tr> <td>At</td> <td>=</td> <td>A. thaliana</td> <td>SyHa</td> <td>=</td> <td>Golden Syrian Hamster</td> </tr> <tr> <td>All</td> <td>=</td> <td>All Species</td> <td>Ha</td> <td>=</td> <td>Hamster</td> </tr> <tr> <td>An</td> <td>=</td> <td>Animal</td> <td>Hu</td> <td>=</td> <td>Human</td> </tr> <tr> <td>ArHa</td> <td>=</td> <td>Armenian Hamster</td> <td>I</td> <td>=</td> <td>Insect</td> </tr> <tr> <td>Av</td> <td>=</td> <td>Avian</td> <td>Ll</td> <td>=</td> <td>Llama</td> </tr> <tr> <td>Bb</td> <td>=</td> <td>Baboon</td> <td>Ma</td> <td>=</td> <td>Mammal</td> </tr> <tr> <td>Ba</td> <td>=</td> <td>Bacteria</td> <td>Mk</td> <td>=</td> <td>Monkey</td> </tr> <tr> <td>Bv</td> <td>=</td> <td>Bovine</td> <td>Mu</td> <td>=</td> <td>Mouse</td> </tr> <tr> <td>Ca</td> <td>=</td> <td>Canine</td> <td>Multi</td> <td>=</td> <td>Multi-species</td> </tr> <tr> <td>Ce</td> <td>=</td> <td>C. Elegans</td> <td>NA</td> <td>=</td> <td>Non-species specific</td> </tr> <tr> <td>Ch</td> <td>=</td> <td>Chicken</td> <td>Or</td> <td>=</td> <td>Orangutan</td> </tr> <tr> <td>ChHa</td> <td>=</td> <td>Chinese Hamster</td> <td>Pl</td> <td>=</td> <td>Plant</td> </tr> <tr> <td>Cm</td> <td>=</td> <td>Cynomolgus Monkey</td> <td>Pm</td> <td>=</td> <td>Primate</td> </tr> <tr> <td>Do</td> <td>=</td> <td>Donkey</td> <td>Po</td> <td>=</td> <td>Porcine</td> </tr> <tr> <td>Dr</td> <td>=</td> <td>Drosophilia</td> <td>Rb</td> <td>=</td> <td>Rabbit</td> </tr> <tr> <td>Ec</td> <td>=</td> <td>E. Coli</td> <td>Rt</td> <td>=</td> <td>Rat</td> </tr> <tr> <td>Eq</td> <td>=</td> <td>Equine</td> <td>RM</td> <td>=</td> <td>Rhesus Macaque</td> </tr> <tr> <td>Fe</td> <td>=</td> <td>Feline</td> <td>Sh</td> <td>=</td> <td>Sheep</td> </tr> <tr> <td>Ft</td> <td>=</td> <td>Ferret</td> <td>Vb</td> <td>=</td> <td>Vertebrate</td> </tr> <tr> <td>Fi</td> <td>=</td> <td>Fish</td> <td>Vi</td> <td>=</td> <td>Virus</td> </tr> <tr> <td>Fu</td> <td>=</td> <td>Fungi</td> <td>Xp</td> <td>=</td> <td>Xenopus</td> </tr> <tr> <td>Ge</td> <td>=</td> <td>Gerbil</td> <td>Ye</td> <td>=</td> <td>Yeast</td> </tr> <tr> <td>GP</td> <td>=</td> <td>Guinea Pig</td> <td>Ze</td> <td>=</td> <td>Zebrafish</td> </tr> <tr> <td>Gt</td> <td>=</td> <td>Goat</td> </tr> </table> <div style="text-align: center;margin-left:25px;margin-right:25px;"> <p>Note: Mouseover a species abbreviation on the product page to display the fullname.</p> </div> </div> </div><div class="clear"></div><div class="grid_10 pos_relative"><div class="ds_blue_border equaltop"><div class="imagesleft equaltop"><h2 class="blueHead">Images</h2> <div class="midBlue"> </div><div class="images"><div id="ss_prev_top" class="cycle-pager"><div class="pager_left_on"></div></div><div class="cycle-slideshow slideshows" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-top" data-cycle-prev="#ss_prev_top" data-cycle-next="#ss_next_top" data-cycle-caption="#image-caption" data-cycle-caption-template="Image {{slideNum}} of {{slideCount}}" data-cycle-slides=".big_thumb_container" data-cycle-carousel-visible="4" id="images_cycle" > <div class="sub_image_wrapper"><div id="cycle-circle-pager-top" class="cycle-circle-pager"></div><div id="image-caption"></div> <a class="enlargeTop">(<div class="dsSprite_magGlass"></div> Enlarge)</a></div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize2/DATA_IL6_M6000_ELISA_936.jpg" class="top_images" rel="gallery" title="" > <img src="//images.novusbio.com/images2/DATA_IL6_M6000_ELISA_936.jpg" class="big_thumb" alt="" title="" /> </a> </div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize2/IL-6_M6000_ELISA_415.jpg" class="top_images" rel="gallery" title="" > <img src="//images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="" title="" /> </a> </div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg" class="top_images" rel="gallery" title="Increased production of proinflammatory cytokines and VEGF in the plasma and chondrocytes in high fat diet (HFD)-feeding mice.(a~d) levels of plasma IL-6 (a), TNF-alpha (b), IL-1 beta (c) and VEGF (d) in the C57BL/6 male mice fed with a normal diet (ND) or HFD for 8 weeks. (n = 5, **P < 0.01). (e~h) Relative mRNA expression of IL-6 (e), TNF-alpha (f), IL-1 beta (g) and VEGF (h) in the chondrocytes isolated from the 8-week ND or HFD-feeding mice. (n = 5, **P < 0.01). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/26271607), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Increased production of proinflammatory cytokines and VEGF in the plasma and chondrocytes in high fat diet (HFD)-feeding mice.(a~d) levels of plasma IL-6 (a), TNF-alpha (b), IL-1 beta (c) and VEGF (d) in the C57BL/6 male mice fed with a normal diet (ND) or HFD for 8 weeks. (n = 5, **P < 0.01). (e~h) Relative mRNA expression of IL-6 (e), TNF-alpha (f), IL-1 beta (g) and VEGF (h) in the chondrocytes isolated from the 8-week ND or HFD-feeding mice. (n = 5, **P < 0.01). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/26271607), licensed under a CC-BY license. Not internally tested by R&D Systems." title="Increased production of proinflammatory cytokines and VEGF in the plasma and chondrocytes in high fat diet (HFD)-feeding mice.(a~d) levels of plasma IL-6 (a), TNF-alpha (b), IL-1 beta (c) and VEGF (d) in the C57BL/6 male mice fed with a normal diet (ND) or HFD for 8 weeks. (n = 5, **P < 0.01). (e~h) Relative mRNA expression of IL-6 (e), TNF-alpha (f), IL-1 beta (g) and VEGF (h) in the chondrocytes isolated from the 8-week ND or HFD-feeding mice. (n = 5, **P < 0.01). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/26271607), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >Increased production of proinflammatory cytokines and VEGF in the plasma and chondrocytes in high fat diet (HFD)-feeding mice.(a~d) levels of plasma IL-6 (a), TNF-alpha (b), IL-1 beta (c) and VEGF (d) in the C57BL/6<a class="openGallery" href="#" data-picnum="2"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/m6000b_mouse-il-6-quantikine-elisa-kit-2282024172116.jpg" class="top_images" rel="gallery" title="PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the culture supernatants were collected, and the amount of TNF-alpha , IL-6, IL-1 beta and IL-10 were measured by ELISA (A-D). Data are represented as mean ± SD from at least 3 independent experiments. *P< 0.05 compared with LPS alone. #P< 0.05. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26367267), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-2282024172116.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the culture supernatants were collected, and the amount of TNF-alpha , IL-6, IL-1 beta and IL-10 were measured by ELISA (A-D). Data are represented as mean ± SD from at least 3 independent experiments. *P< 0.05 compared with LPS alone. #P< 0.05. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26367267), licensed under a CC-BY license. Not internally tested by R&D Systems." title="PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the culture supernatants were collected, and the amount of TNF-alpha , IL-6, IL-1 beta and IL-10 were measured by ELISA (A-D). Data are represented as mean ± SD from at least 3 independent experiments. *P< 0.05 compared with LPS alone. #P< 0.05. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26367267), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >PYC suppressed LPS-induced proinflammatory cytokine production in BV2 microglia.Cells were incubated with the indicated concentrations of PYC or vehicle for 1h before LPS treatment (500ng/mL). After 24 h incubation, the<a class="openGallery" href="#" data-picnum="3"> ...read more</a></div> </div></div><div id="ss_next_top" class="cycle-pager"><div class="pager_right_on"></div></div></div></div><div class="productsright pos_relative equaltop"><h2 class="blueHead">Product Details</h2> <div class="midBlue">Summary</div><table class="ds_list"><tr class="lined"> <td><strong>Reactivity</strong></td> <td><span title='Mouse'>Mu</span><span class="myModal">Species Glossary</span></td> </tr><tr class="lined"> <td><strong>Applications</strong></td> <td><span title='ELISA'>ELISA</span></td> </tr><tr class="lined"> <td><strong>Conjugate</strong></td> <td><div>HRP</div></td> </tr></table></div> </div></div><div class="grid_6"><div></div> <div class="ds_blue_border equaltop"> <h2 class="blueHead_nopadding">Order Details</h2><ul class="ds_details"><li class="add-to-cart" data-type="full" data-prodname="Mouse IL-6 Quantikine ELISA Kit, 2 Plate" data-catnum="M6000B" 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data-rendered="false"></div></td></tr></span> </div> </div><div class="clear"></div><div class="grid_10"><div><div id="ds_tabs" style="display:none;"> <div class="ds_tab_active" id="dsTabs_datasheet" data-anchor_desc="datasheet">Datasheet</div> <div class="ds_tab" id="dsTabs_reviews-publications" data-anchor_desc="reviews-publications">Reviews & Publications</div> <div class="ds_tab" id="dsTabs_protocols-faqs" data-anchor_desc="protocols-faqs">Protocols & FAQs</div> <div class="ds_tab" id="dsTabs_supportresearch" data-anchor_desc="supportresearch">Support & Research</div> </div><div class="ds_tab_content equalbottom" id="content_datasheet" > <a id="datasheet"></a><h2 class=greyHead2>Mouse IL-6 Quantikine ELISA Kit, 2 Plate Summary</h2> <div class="ds_info"> <a id="tab1details"></a> <table class="ds_list wide" style="table-layout:fixed;"> <tr class="lined"> <td><strong>Background</strong></td> <td><div class="backgrounds">The Quantikine Mouse IL-6 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse IL-6 <span>in cell culture supernates, serum, and plasma. It contains <EM>E. coli</EM>-expressed recombinant mouse IL-6 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse IL-6. Results obtained using natural mouse IL-6 sho<span class="summaryElipse">...</span><span class="hide summaryMore">wed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-6.</span></span><div class="summaryShow"><div class="ui-icon ui-icon-triangle-1-s"></div>Show More</div></div></td> </tr><tr class="lined"> <td><strong>Additional Information</strong></td> <td><div>2 plate pack size in process of discontinuation</div></td> </tr><tr class="lined"> <td><strong>Specificity</strong></td> <td><div>Natural and recombinant mouse IL-6</div></td> </tr><tr class="lined"> <td><strong>Source</strong></td> <td><div>N/A</div></td> </tr><tr class="lined"> <td><strong>Inter-Assay</strong></td> <td><div>See <a href="//resources.rndsystems.com/pdfs/datasheets/m6000b.pdf" target="_blank">PDF Datasheet</a> for details</div></td> </tr><tr class="lined"> <td><strong>Intra-Assay</strong></td> <td><div>See <a href="//resources.rndsystems.com/pdfs/datasheets/m6000b.pdf" target="_blank">PDF Datasheet</a> for details</div></td> </tr><tr class="lined"> <td><strong>Spike Recovery</strong></td> <td><div>See <a href="//resources.rndsystems.com/pdfs/datasheets/m6000b.pdf" target="_blank">PDF Datasheet</a> for details</div></td> </tr><tr class="lined"> <td><strong>Sample Volume</strong></td> <td><div>See <a href="//resources.rndsystems.com/pdfs/datasheets/m6000b.pdf" target="_blank">PDF Datasheet</a> for details</div></td> </tr><tr class="lined"> <td><strong>Gene</strong></td> <td><div>Il6</div></td> </tr> </table> </div> <h2 class="greyHead2">Applications/Dilutions</h2> <div class="ds_info"> <a id="tab1appsdiluts"></a> <table class="ds_list wide"> <tr class="lined"> <td><strong>Dilutions</strong></td> <td> <ul class="ds_noDotList"><li>ELISA </li> </ul> </td> </tr><tr class="lined"> <td><strong>Application Notes</strong></td> <td><div>No significant interference observed with available related molecules.</div></td> </tr><tr class="lined"> <td><strong>Publications</strong></td> <td> <table> <tr> <td>Read <a href="#PublicationSection"> Publications</a> using<br/> M6000B in the following applications:<br /><br /> <ul class="information-list"><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="ELISA Capture">ELISA Capture</a> </div><div class="information-data">5 publications</div></li></ul></td> </tr> </table> </td> </tr> </table> </div> <h2 class="greyHead2">Packaging, Storage & Formulations</h2><div class="ds_info"><table class="ds_list"><tr class="lined"> <td><strong>Storage</strong></td> <td><div>Store the unopened product at 2 - 8 °C. Do not use past expiration date.</div></td> </tr></table></div> <h2 class="greyHead2">Notes</h2><div class="ds_info"> <a id="tab1notes"></a> <div>This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.</div> </div><h2 class="greyHead2">Alternate Names for Mouse IL-6 Quantikine ELISA Kit, 2 Plate</h2> <div class="ds_info"> <a id="tab1altnames"></a> <div class="information-list"> <ul><li>B-cell differentiation factor</li><li>B-cell stimulatory factor 2</li><li>BSF2</li><li>BSF-2</li><li>CDF</li><li>CTL differentiation factor </li><li>HSF</li><li>hybridoma growth factor</li><li>IFNB2</li><li>IFN-beta-2</li><li>IL6</li><li>IL-6</li><li>Interferon beta-2</li><li>interleukin 6 (interferon, beta 2)</li><li>interleukin BSF-2</li><li>interleukin-6</li><li>MGI-2A</li></ul></div> </div> <h2 class="greyHead2">Background</h2> <div class="ds_info"> <a id="tab1background"></a> <div>Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.<p>IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor. </p><p>IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. 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A specific band was detected for IL-8/CXCL8 at approximately 10&amp;nbsp;kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images2/mab208_human-il-8-cxcl8-mab-clone-6217-western-blot-1882021143847.jpg" alt="Western Blot CXCL8/IL-8 Antibody (6217) [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav6" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-6" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cxcl8-il-8-antibody-6217_mab208#ReviewsSection"> <div class="sprite_4Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/cxcl8-il-8-antibody-6217_mab208#PublicationSection"> <div class="sprite_pubBook"></div> (183 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="285-IF"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-ifn-gamma-protein_285-if" style="overflow: hidden; width: 280px;" title="IFN-gamma [Unconjugated]">IFN-gamma<br> [Unconjugated]</a>    </div><div class="sub-header">285-IF</div> <div class="images_customers"><div id="ss_prev_cav7" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-7" data-cycle-prev="#ss_prev_cav7" data-cycle-next="#ss_next_cav7" data-cycle-slides="div.big_thumb_cust_container" data-index=7 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-ifn-gamma-protein_285-if" title="Recombinant Human IFN-gamma (Catalog # 285‑IF) demonstrates anti-viral activity in HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The activity is over 2-fold greater than the top competitor's IFN-gamma ." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images2/IFNgamma_285IF_2848.jpg" alt="Bioactivity IFN-gamma [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-ifn-gamma-protein_285-if" title="1 μg/lane of Recombinant Human IFN-gamma was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images2/IFN-gamma_285-IF_230.jpg" alt="SDS-PAGE IFN-gamma [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-ifn-gamma-protein_285-if" title="Recombinant Human IFN-gamma (Catalog # 285-IF) has a molecular weight (MW) of 34.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation)." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/285-if_recombinant-human-ifn-gamma-protein-sec-mals-1520239228..jpg" alt="SEC-MALS IFN-gamma [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav7" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-7" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-ifn-gamma-protein_285-if#ReviewsSection"> <div class="sprite_5Stars"></div> (2 Reviews</a>) </div> <div class="tiny"> <a href="/products/recombinant-human-ifn-gamma-protein_285-if#PublicationSection"> <div class="sprite_pubBook"></div> (451 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="MAB1799"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/stat3-antibody-232209_mab1799" style="overflow: hidden; width: 280px;" title="STAT3 Antibody (232209) [Unconjugated]">STAT3 Antibody<br> (232209) [Unconjugate</a>    </div><div class="sub-header">MAB1799</div> <div class="images_customers"><div id="ss_prev_cav8" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-8" data-cycle-prev="#ss_prev_cav8" data-cycle-next="#ss_next_cav8" data-cycle-slides="div.big_thumb_cust_container" data-index=8 ><div class="big_thumb_cust_container"> <a href="/products/stat3-antibody-232209_mab1799" title="STAT3 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line treated with IFN-alpha 1, but is not detected in STAT3 knockout (KO) HeLa cell line using Mouse Anti-Human/ Mouse/Rat STAT3 Monoclonal Antibody (Catalog # MAB1799) at 1 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&amp;#8482; 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/STAT3_MAB1799_Simple_Western_21000.jpg" alt="Knockout Validated STAT3 Antibody (232209) [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/stat3-antibody-232209_mab1799" title="Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, HeLa human cervical epithelial carcinoma cell line, NIH-3T3 mouse embryonic fibroblast cell line, and PC-12 rat adrenal pheochromocytoma cell line. PVDF membrane was probed with 0.1 µg/mL of Mouse Anti-Human STAT3 Monoclonal Antibody (Catalog # MAB1799) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for STAT3 at approximately 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/STAT3_MAB1799_Western_Blot_5993.jpg" alt="Western Blot STAT3 Antibody (232209) [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/stat3-antibody-232209_mab1799" title="Western blot shows lysates of HeLa human cervical epithelial carcinoma parental cell line, STAT1 knockout (KO) HeLa cell line, STAT2 KO HeLa cell line, STAT3 KO HeLa cell line, STAT5a KO HeLa cell line, STAT5b KO HeLa cell line, STAT6 KO HeLa cell line,. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human/Mouse/Rat STAT3 Monoclonal Antibody (Catalog # MAB1799) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for STAT3 at approximately 80 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the STAT3 knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/STAT3_MAB1799_Knockout_Validated_21531.jpg" alt="Knockout Validated STAT3 Antibody (232209) [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav8" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-8" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/stat3-antibody-232209_mab1799#PublicationSection"> <div class="sprite_pubBook"></div> (22 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC, IP, ICFlow, KO, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="DCP00"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/human-ccl2-mcp-1-quantikine-elisa-kit_dcp00" style="overflow: hidden; width: 280px;" title="CCL2/JE/MCP-1 [HRP]">CCL2/JE/MCP-1 [HRP]</a>    </div><div class="sub-header">DCP00</div> <div class="images_customers"><div id="ss_prev_cav9" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-9" data-cycle-prev="#ss_prev_cav9" data-cycle-next="#ss_next_cav9" data-cycle-slides="div.big_thumb_cust_container" data-index=9 ><div class="big_thumb_cust_container"> <a href="/products/human-ccl2-mcp-1-quantikine-elisa-kit_dcp00" title="" class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/CCL2_DCP00_ELISA_67.jpg" alt="N/A CCL2/JE/MCP-1 [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-ccl2-mcp-1-quantikine-elisa-kit_dcp00" title="" class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_633.jpg" alt="N/A CCL2/JE/MCP-1 [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-ccl2-mcp-1-quantikine-elisa-kit_dcp00" title="" class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_634.jpg" alt="N/A CCL2/JE/MCP-1 [HRP]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav9" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-9" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/human-ccl2-mcp-1-quantikine-elisa-kit_dcp00#PublicationSection"> <div class="sprite_pubBook"></div> (255 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ELISA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF5739"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/csrp1-antibody_af5739" style="overflow: hidden; width: 280px;" title="CSRP1 Antibody">CSRP1 Antibody</a>    </div><div class="sub-header">AF5739</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-10" data-cycle-prev="#ss_prev_cav10" data-cycle-next="#ss_next_cav10" data-cycle-slides="div.big_thumb_cust_container" data-index=10 ><div class="big_thumb_cust_container"> <a href="/products/csrp1-antibody_af5739" title="Western blot shows lysates of ME-180 human cervical epithelial carcinoma cell line, HT-2 mouse T cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL Goat Anti-Human/Mouse/Rat CSRP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5739) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). For additional reference, recombinant human CSRP1, CSRP2, CSRP3 (5 ng/lane) were included. A specific band for CSRP1 was detected at approximately 23 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images2/CSRP1_AF5739_Western_Blot_5830.jpg" alt="Western Blot CSRP1 Antibody" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="7734-LF"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-lif-protein_7734-lf" style="overflow: hidden; width: 280px;" title="LIF [Unconjugated]">LIF [Unconjugated]</a>    </div><div class="sub-header">7734-LF</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-11" data-cycle-prev="#ss_prev_cav11" data-cycle-next="#ss_next_cav11" data-cycle-slides="div.big_thumb_cust_container" data-index=11 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-lif-protein_7734-lf" title="LIF [Unconjugated]" class="cust_viewed_11"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="LIF [Unconjugated]" title="LIF [Unconjugated]" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-lif-protein_7734-lf#PublicationSection"> <div class="sprite_pubBook"></div> (31 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="DVE00"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/human-vegf-quantikine-elisa-kit_dve00" style="overflow: hidden; width: 280px;" title="VEGF [HRP]">VEGF [HRP]</a>    </div><div class="sub-header">DVE00</div> <div class="images_customers"><div id="ss_prev_cav12" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-12" data-cycle-prev="#ss_prev_cav12" data-cycle-next="#ss_next_cav12" data-cycle-slides="div.big_thumb_cust_container" data-index=12 ><div class="big_thumb_cust_container"> <a href="/products/human-vegf-quantikine-elisa-kit_dve00" title="" class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_871.jpg" alt="N/A VEGF [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-vegf-quantikine-elisa-kit_dve00" title="" class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_872.jpg" alt="N/A VEGF [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-vegf-quantikine-elisa-kit_dve00" title="" class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images2/VEGF_DVE00_ELISA_208.jpg" alt="N/A VEGF [HRP]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav12" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-12" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/human-vegf-quantikine-elisa-kit_dve00#PublicationSection"> <div class="sprite_pubBook"></div> (682 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ELISA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-56583"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583" style="overflow: hidden; width: 280px;" title="NFkB p105/p50 Antibody (2J10D7) - BSA Free">NFkB p105/p50<br> Antibody (2J10D7) - B ...</a>    </div><div class="sub-header">NB100-56583</div> <div class="images_customers"><div id="ss_prev_cav13" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-13" data-cycle-prev="#ss_prev_cav13" data-cycle-next="#ss_next_cav13" data-cycle-slides="div.big_thumb_cust_container" data-index=13 ><div class="big_thumb_cust_container"> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583" title="Flow Cytometry: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - An intracellular stain was performed on Jurkat cells with NFkB p105/p50 Antibody (2J10D7) NB100-56583C (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes. Both antibodies were conjugated to Dylight 650." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/NFkB-p105-p50-Antibody-2J10D7-Flow-Cytometry-NB100-56583-img0005.jpg" alt="Flow Cytometry NFkB p105/p50 Antibody (2J10D7) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583" title="Flow Cytometry: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - An intracellular stain was performed on HeLa cells with NFkB p105/p50 Antibody (2J10D7) NB100-56583C (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes. Both antibodies were conjugated to Dylight 650." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/NFkB-p105-p50-Antibody-2J10D7-Flow-Cytometry-NB100-56583-img0006.jpg" alt="Flow Cytometry NFkB p105/p50 Antibody (2J10D7) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583" title="Flow Cytometry: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - An intracellular stain was performed on U2-OS cells with NFkB p105/p50 [2J10D7] Antibody NB100-56583C (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to DyLight 650." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/NFkB-p105-p50-Antibody-2J10D7-Flow-Cytometry-NB100-56583-img0007.jpg" alt="Flow Cytometry NFkB p105/p50 Antibody (2J10D7) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav13" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-13" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/nfkb-p105-p50-antibody-2j10d7_nb100-56583#PublicationSection"> <div class="sprite_pubBook"></div> (5 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Rb, Rt</div><div class="tiny"><strong>Applications:</strong> Flow, IHC, IHC-P, KO, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="203-IL"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-il-3-protein_203-il" style="overflow: hidden; width: 280px;" title="IL-3 [Unconjugated]">IL-3 [Unconjugated]</a>    </div><div class="sub-header">203-IL</div> <div class="images_customers"><div id="ss_prev_cav14" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-14" data-cycle-prev="#ss_prev_cav14" data-cycle-next="#ss_next_cav14" data-cycle-slides="div.big_thumb_cust_container" data-index=14 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-il-3-protein_203-il" title="1 μg/lane of Recombinant Human IL-3 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/IL-3_203-IL_345.jpg" alt="SDS-PAGE IL-3 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-il-3-protein_203-il" title="Recombinant Human IL-3 (Catalog # 203-IL) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50 for this effect is 0.02-0.1 ng/mL." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/IL-3_203-IL_347.jpg" alt="Bioactivity IL-3 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-il-3-protein_203-il" title="Recombinant Human IL-3 Protein (Catalog # 203-IL) has a molecular weight (MW) of 14.6 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer. " class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images/203-il_recombinant-human-il-3-protein-sec-mals-133202482656..jpg" alt="SEC-MALS IL-3 [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav14" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-14" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-il-3-protein_203-il#PublicationSection"> <div class="sprite_pubBook"></div> (216 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="7954-GM/CF"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-gm-csf-cho-expressed-protein-cf_7954-gm-cf" style="overflow: hidden; width: 280px;" title="GM-CSF [Unconjugated]">GM-CSF<br> [Unconjugated]</a>    </div><div class="sub-header">7954-GM/CF</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-15" data-cycle-prev="#ss_prev_cav15" data-cycle-next="#ss_next_cav15" data-cycle-slides="div.big_thumb_cust_container" data-index=15 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-gm-csf-cho-expressed-protein-cf_7954-gm-cf" title="Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 6-30 pg/mL." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/protein/7954-gmcf_recombinant-human-gm-csf-cho-expressed-protein-cf-bioactivity-272020121514.jpg" alt="Bioactivity GM-CSF [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-gm-csf-cho-expressed-protein-cf_7954-gm-cf#PublicationSection"> <div class="sprite_pubBook"></div> (3 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-56566"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/tlr4-antibody-76b3571_nb100-56566" style="overflow: hidden; width: 280px;" title="TLR4 Antibody (76B357.1) - BSA Free">TLR4 Antibody<br> (76B357.1) - BSA Free</a>    </div><div class="sub-header">NB100-56566</div> <div class="images_customers"><div id="ss_prev_cav16" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-16" data-cycle-prev="#ss_prev_cav16" data-cycle-next="#ss_next_cav16" data-cycle-slides="div.big_thumb_cust_container" data-index=16 ><div class="big_thumb_cust_container"> <a href="/products/tlr4-antibody-76b3571_nb100-56566" title="Dual RNAscope ISH-IHC: TLR4 Antibody (76B357.1) [NB100-56566] - FFPE tissue sections of human tonsil were probed for TLR4 mRNA (ACD RNAScope Probe, ACD catalog # 311281; Fast Red chromogen, ACD catalog # 322750). Adjacent tissue section was processed for immunohistochemistry using Mouse Monoclonal (Novus Biologicals catalog # NB100-56566) at 5ug/mL with 1 hour incubation at room temperature followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to lymphocytes." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/TLR4-Antibody-76B357-1-Dual-RNAscope-ISH-IHC-NB100-56566-img0036.jpg" alt="Dual RNAscope ISH-IHC TLR4 Antibody (76B357.1) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/tlr4-antibody-76b3571_nb100-56566" title="Immunohistochemistry: TLR4 Antibody (76B357.1) [NB100-56566] - Immunofluorescent staining of TMAs. Representative tissue cores from normal (I), adenomatous polyps (II), and CRC (III and IV) are shown. Image collected and cropped by CiteAb from the following publication (https://www.jeccr.com/content/33/1/45), licensed under a CC-BY license." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/TLR4-Antibody-76B357-1-Immunohistochemistry-NB100-56566-img0037.jpg" alt="Immunohistochemistry TLR4 Antibody (76B357.1) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/tlr4-antibody-76b3571_nb100-56566" title="Immunohistochemistry: TLR4 Antibody (76B357.1) [NB100-56566] - Pericryptal Myofibroblasts are Responsible for Increased TLR4 Expression in a Subset of CRCs. Double-stained immunofluorescence for TLR4 (green) and vimentin (red) in normal (I), adenoma (II), and colon adenocarcinoma (III) (10x). In the stromal compartment of CRCs, immunofluorescent staining for TLR4 localized to the pericryptal myofibroblasts in a subset of samples. Image collected and cropped by CiteAb from the following publication (https://www.jeccr.com/content/33/1/45), licensed under a CC-BY license." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/TLR4-Antibody-76B357-1-Immunohistochemistry-NB100-56566-img0040.jpg" alt="Immunohistochemistry TLR4 Antibody (76B357.1) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav16" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-16" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/tlr4-antibody-76b3571_nb100-56566#ReviewsSection"> <div class="sprite_4Stars"></div> (5 Reviews</a>) </div> <div class="tiny"> <a href="/products/tlr4-antibody-76b3571_nb100-56566#PublicationSection"> <div class="sprite_pubBook"></div> (140 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Bv, Hu, Ma, Mu, Po, Rt</div><div class="tiny"><strong>Applications:</strong> B/N, ChIP, CyTOF-ready, DB, Dual ISH-IHC, ELISA(Cap), ELISA, Flow-CS, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, KD, KO, PAGE, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="M6000B"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/mouse-il-6-quantikine-elisa-kit-2-plate_m6000b" style="overflow: hidden; width: 280px;" title="Mouse IL-6 Quantikine ELISA Kit, 2 Plate">Mouse IL-6<br> Quantikine ELISA Kit, ...</a>    </div><div class="sub-header">M6000B</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-17" data-cycle-prev="#ss_prev_cav17" data-cycle-next="#ss_next_cav17" data-cycle-slides="div.big_thumb_cust_container" data-index=17 ><div class="big_thumb_cust_container"> <a href="/products/mouse-il-6-quantikine-elisa-kit-2-plate_m6000b" title="Mouse IL-6 Quantikine ELISA Kit, 2 Plate" class="cust_viewed_17"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="Mouse IL-6 Quantikine ELISA Kit, 2 Plate" title="Mouse IL-6 Quantikine ELISA Kit, 2 Plate" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Mu</div><div class="tiny"><strong>Applications:</strong> ELISA</div> </div> </div> </div></div> </div><div id="cav_next"><div class="sprite_rightArrow"></div></div> <div class="clear"></div><div class="ds_info"><div class="prop_65_warning">&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.</div></div></div> <div class="ds_tab_content equalbottom" id="content_reviews-publications"> <a id="reviews-publications"></a><a id="PublicationSection"></a><h2 class="greyHead2">Publications for IL-6 (M6000B)(659)</h2><div class="ds_info"> <div>We have publications tested in 6 confirmed species: Human, Mouse, Rat, Mouseq, Transgenic Mouse, Xenograft.<br /><br />We have publications tested in 1 application: ELISA Capture.<br /><br /><div class="align-right"> <button class="greybutton btn_width" name="novusreview" onclick="window.location='/publications'"; >Submit a Publication</button><br /> </div> </div><div> <div class="filterParent"> <div class="publications_filterList" id="pubapp"> <div class="blueHead">Filter By Application</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="ELISA Capture"> <div style="display:inline;">ELISA Capture</div> (5)</div><div class="filter_clear" data-type="publication" data-filter="application">All Applications</div></div> <div class="publications_filterList" id="pubspec"> <div class="blueHead">Filter By Species</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Human"> <div style="display:inline;">Human</div> (7)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Mouse"> <div style="display:inline;">Mouse</div> (647)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Rat"> <div style="display:inline;">Rat</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Mouseq"> <div style="display:inline;">Mouseq</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Transgenic Mouse"> <div style="display:inline;">Transgenic Mouse</div> (9)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Xenograft"> <div style="display:inline;">Xenograft</div> (1)</div><div class="filter_clear" data-type="publication" data-filter="species">All Species</div></div> </div></div> <div class="clear"></div> <div id="publications_list">Showing Publications 1 - <span id="appcnt">10</span> of 659. <a class="pubs_showall">Show All 659 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a><table class="wide lightPad tablesorter" id="publications_list_table"> <thead> <tr> <th>Publications using M6000B</th> <th>Applications</th> <th>Species</th> </tr> </thead> <tbody><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39337370" target="_blank" rel="nofollow"> Abdollahzadeh, B;Cantale Aeo, NM;Giordano, N;Orlando, A;Basciani, M;Peruzzi, G;Grazioli, P;Screpanti, I;Felli, MP;Campese, AF; The NF-?B1/p50 Subunit Influences the Notch/IL-6-Driven Expansion of Myeloid-Derived Suppressor Cells in Murine T-Cell Acute Lymphoblastic Leukemia International journal of molecular sciences 2024-09-13 [PMID: 39337370] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Human, Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39296097" target="_blank" rel="nofollow"> Gu, L;Yin, Y;Liu, M;Yu, L; Acacetin protects against acute lung injury by upregulating SIRT1/ NF-?B pathway Heliyon 2024-09-15 [PMID: 39296097] (Human, Mouse) </a></td> <td valign="top"></td> <td valign="top">Human, Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39293315" target="_blank" rel="nofollow"> Song, JY;Lee, YJ;Lee, SH;Lee, JY; Enoximone alleviates atopic dermatitis-like skin inflammation via inhibition of type 2 T helper cell development International immunopharmacology 2024-09-17 [PMID: 39293315] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39239848" target="_blank" rel="nofollow"> Pacifico, T;Stolfi, C;Tomassini, L;Luiz-Ferreira, A;Franzè, E;Ortenzi, A;Colantoni, A;Sica, GS;Sambucci, M;Monteleone, I;Monteleone, G;Laudisi, F; Rafoxanide negatively modulates STAT3 and NF-?B activity and inflammation-associated colon tumorigenesis Cancer science 2024-09-06 [PMID: 39239848] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39217915" target="_blank" rel="nofollow"> Xie, F;Kitagawa, Y;Ogata, H;Yasuhara, S;You, Z;Jeevendra Martyn, JA; Morphine induces inflammatory responses via both TLR4 and cGAS-STING signaling pathways Cytokine 2024-08-31 [PMID: 39217915] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39189614" target="_blank" rel="nofollow"> Ben-Crentsil, NA;Mohammed Ismail, W;Balasis, ME;Newman, H;Quintana, A;Binder, M;Kruer, T;Neupane, S;Ferrall-Fairbanks, MC;Fernandez, J;Lasho, TL;Finke, CM;Ibrahim, ML;McGraw, KL;Wysota, M;Aldrich, AL;Ryder, CB;Letson, CT;Traina, J;McLemore, AF;Droin, N;Shastri, A;Yun, S;Solary, E;Sallman, DA;Beg, AA;Ma, L;Gaspar-Maia, A;Patnaik, MM;Padron, E; RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis Cancer discovery 2024-08-27 [PMID: 39189614] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39170711" target="_blank" rel="nofollow"> Kim, H;Choi, J;Seo, J;Lim, H;Kang, SK; CKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases Frontiers in pharmacology 2024-08-07 [PMID: 39170711] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Transgenic Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39169397" target="_blank" rel="nofollow"> Bernard, A;Eggstein, C;Tang, L;Keller, M;Körner, A;Mirakaj, V;Rosenberger, P; Plexin C1 influences immune response to intracellular LPS and survival in murine sepsis Journal of biomedical science 2024-08-21 [PMID: 39169397] (Transgenic Mouse) </a></td> <td valign="top"></td> <td valign="top">Transgenic Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39159557" target="_blank" rel="nofollow"> Su, J;Chen, K;Sang, X;Feng, Z;Zhou, F;Zhao, H;Wu, S;Deng, X;Lin, C;Lin, X;Xie, L;Ye, H;Chen, Q; Huperzine a ameliorates sepsis-induced acute lung injury by suppressing inflammation and oxidative stress via ?7 nicotinic acetylcholine receptor International immunopharmacology 2024-08-18 [PMID: 39159557] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39154534" target="_blank" rel="nofollow"> Su, J;Xiao, J;Deng, X;Lin, X;Xie, L;Ye, H;Lin, C;Zhou, F;Wu, S; Combining Aloin with TIENAM ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating abdominal cavity microbiota International immunopharmacology 2024-08-17 [PMID: 39154534] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39129303" target="_blank" rel="nofollow"> Shin, JY;Cho, BO;Park, JH;Kang, ES;Kim, JH;Ha, HY;Kim, YS;Jang, SI; Diospyros lotus leaf extract and its main component myricitrin inhibit itch?related IL?6 and IL?31 by suppressing microglial inflammation and microglial?mediated astrocyte activation Molecular medicine reports 2024-10-01 [PMID: 39129303] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39120972" target="_blank" rel="nofollow"> Liu, X;Cui, L;Tao, Y;Xia, S;Hou, J;Cao, X;Xu, S; The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response Cell reports 2024-08-08 [PMID: 39120972] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39089657" target="_blank" rel="nofollow"> Tian, R;Li, R;Chen, Y;Liu, D;Li, Y;He, S;Pan, T;Qu, H;Tan, R; Shenfu injection ameliorates endotoxemia-associated endothelial dysfunction and organ injury via inhibiting PI3K/Akt-mediated glycolysis Journal of ethnopharmacology 2024-07-30 [PMID: 39089657] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse, Transgenic Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39020175" target="_blank" rel="nofollow"> Widjaja, AA;Lim, WW;Viswanathan, S;Chothani, S;Corden, B;Dasan, CM;Goh, JWT;Lim, R;Singh, BK;Tan, J;Pua, CJ;Lim, SY;Adami, E;Schafer, S;George, BL;Sweeney, M;Xie, C;Tripathi, M;Sims, NA;Hübner, N;Petretto, E;Withers, DJ;Ho, L;Gil, J;Carling, D;Cook, SA; Inhibition of IL-11 signalling extends mammalian healthspan and lifespan Nature 2024-07-17 [PMID: 39020175] (Mouse, Transgenic Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse, Transgenic Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38997291" target="_blank" rel="nofollow"> Zahraeifard, S;Xiao, Z;So, JY;Ahad, A;Montoya, S;Park, WY;Sornapudi, T;Andohkow, T;Read, A;Kedei, N;Koparde, V;Yang, H;Lee, M;Wong, N;Cam, M;Wang, K;Ruppin, E;Luo, J;Hollander, C;Yang, L; Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression Nature communications 2024-07-12 [PMID: 38997291] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38994019" target="_blank" rel="nofollow"> Liu, J;Huang, B;Rao, Y;Guo, L;Cai, C;Gao, D;Kong, D;Wang, G;Xiong, Y;Cui, R;Zhang, M;Chen, C; Intraductal photothermal ablation: a noninvasive approach for early breast cancer treatment and prevention Theranostics 2024-07-01 [PMID: 38994019] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38986724" target="_blank" rel="nofollow"> Lei, Z;Krishnamachary, B;Khan, NZ;Ji, Y;Li, Y;Li, H;Brunner, K;Faden, AI;Jones, JW;Wu, J; Spinal cord injury disrupts plasma extracellular vesicles cargoes leading to neuroinflammation in the brain and neurological dysfunction in aged male mice Brain, behavior, and immunity 2024-07-08 [PMID: 38986724] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38930591" target="_blank" rel="nofollow"> Zhou, B;Elean, M;Arce, L;Fukuyama, K;Tomotsune, K;Dentice Maidana, S;Saha, S;Namai, F;Nishiyama, K;Vizoso-Pinto, MG;Villena, J;Kitazawa, H; The Mucus-Binding Factor Mediates Lacticaseibacillus rhamnosus CRL1505 Adhesion but Not Immunomodulation in the Respiratory Tract Microorganisms 2024-06-16 [PMID: 38930591] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38886466" target="_blank" rel="nofollow"> Qasim, R;Thiab, TA;Alhindi, T;Al-Hunaiti, A;Imraish, A; The Nurr1 ligand indole acetic acid hydrazide loaded onto ZnFe2O4 nanoparticles suppresses proinflammatory gene expressions in SimA9 microglial cells Scientific reports 2024-06-17 [PMID: 38886466] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38788444" target="_blank" rel="nofollow"> Liu, X;Liu, Y;Su, X;Jiang, L;Tang, G;Wang, Y; Geranylgeranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and anti-oxidative effect International immunopharmacology 2024-05-23 [PMID: 38788444] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38614406" target="_blank" rel="nofollow"> Deng, M;Hou, Y;Liu, J;He, J;Lan, Z;Xiao, H; Mesenchymal stem cell-derived exosomes overexpressing SRC-3 protect mice from cerebral ischemia by inhibiting ferroptosis Brain research bulletin 2024-04-16 [PMID: 38614406] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38427558" target="_blank" rel="nofollow"> Koller, BH;Nguyen, M;Snouwaert, JN;Gabel, CA;Ting, JP; Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases Cell reports 2024-02-29 [PMID: 38427558] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38320873" target="_blank" rel="nofollow"> Miyashita, Y;Kanou, T;Fukui, E;Matsui, T;Kimura, T;Ose, N;Funaki, S;Shintani, Y; A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury Transplantation proceedings 2024-02-05 [PMID: 38320873] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38320455" target="_blank" rel="nofollow"> Ouyang, P;Cai, Z;Peng, J;Lin, S;Chen, X;Chen, C;Feng, Z;Wang, L;Song, G;Zhang, Z; SELENOK-dependent CD36 palmitoylation regulates microglial functions and A? phagocytosis Redox biology 2024-02-01 [PMID: 38320455] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse, Transgenic Mouse, Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38233383" target="_blank" rel="nofollow"> Wei, Y;Li, J;Li, J;Liu, C;Guo, X;Liu, Z;Zhang, L;Bao, S;Wu, X;Su, W;Wang, X;Zhang, J;Dong, W; Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis Cell death & disease 2024-01-17 [PMID: 38233383] (Mouse, Transgenic Mouse, Human) </a></td> <td valign="top"></td> <td valign="top">Mouse, Transgenic Mouse, Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38223538" target="_blank" rel="nofollow"> Han, G;Kim, H;Jang, H;Kim, ES;Kim, SH;Yang, Y; Oral TNF-? siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease Bioactive materials 2024-04-01 [PMID: 38223538] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38203313" target="_blank" rel="nofollow"> Park, C;Ji, SY;Hwangbo, H;Shin, SY;Kim, MY;Lee, K;Kim, DH;Cho, BR;Lee, H;Choi, YH;You, HJ; Enhancement of Immune Functions by Limosilactobacillus reuteri KBL346: In Vitro and In Vivo Studies International journal of molecular sciences 2023-12-21 [PMID: 38203313] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a 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A;Jang, CH;Kim, CS;Hwang, YH; Isobavachin, a main bioavailable compound in Psoralea corylifolia, alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the MAPK and NF-?B signaling pathways Journal of ethnopharmacology 2023-11-25 [PMID: 38012970] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38004599" target="_blank" rel="nofollow"> Lee, SG;Park, CH;Kang, H; Effect of E. cava and C. indicum Complex Extract on Phorbol 12-Myristate 13-Acetate (PMA)-Stimulated Inflammatory Response in Human Pulmonary Epithelial Cells and Particulate Matter (PM)2.5-Induced Pulmonary Inflammation in Mice Pharmaceutics 2023-11-13 [PMID: 38004599] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38003345" target="_blank" rel="nofollow"> Haller, AM;Wolfkiel, PR;Jaeschke, A;Hui, DY; Inactivation of Group 1B Phospholipase A2 Enhances Disease Recovery and Reduces Experimental Colitis in Mice International journal of molecular sciences 2023-11-10 [PMID: 38003345] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37995573" target="_blank" rel="nofollow"> Xu, M;Shi, F;Gao, Y;Han, S;Huang, C;Hou, Q;Wen, X;Wang, B;Zhu, Z;Zou, L;Xiong, M;Dong, W;Tan, J; Arabinose confers protection against intestinal injury by improving integrity of intestinal mucosal barrier International immunopharmacology 2023-11-22 [PMID: 37995573] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37958756" target="_blank" rel="nofollow"> Elean, M;Raya Tonetti, F;Fukuyama, K;Arellano-Arriagada, L;Namai, F;Suda, Y;Gobbato, N;Nishiyama, K;Villena, J;Kitazawa, H; Immunobiotic Ligilactobacillus salivarius FFIG58 Confers Long-Term Protection against Streptococcus pneumoniae International journal of molecular sciences 2023-10-30 [PMID: 37958756] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37950418" target="_blank" rel="nofollow"> Chen, F;Xiong, BR;Xian, SY;Zhang, J;Ding, RW;Xu, M;Zhang, ZZ; Fibroblast growth factor 5 protects against spinal cord injury through activating AMPK pathway Journal of cellular and molecular medicine 2023-11-10 [PMID: 37950418] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" 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href="http://www.ncbi.nlm.nih.gov/pubmed/37777030" target="_blank" rel="nofollow"> Hou, C;Jiang, X;Sheng, W;Zhang, Y;Lin, Q;Hong, S;Zhao, J;Wang, T;Ye, X; Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway Journal of ethnopharmacology 2023-09-28 [PMID: 37777030] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37773169" target="_blank" rel="nofollow"> Wang, C;Feng, L;Zhu, L;Wu, L;Chen, B;Cui, C;Yang, M;Gao, Y;Jiang, P; Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p Cell death & disease 2023-09-29 [PMID: 37773169] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37762104" target="_blank" rel="nofollow"> Su, J;Guan, B;Su, Q;Hu, S;Wu, S;Tong, Z;Zhou, F; Fucoxanthin Ameliorates Sepsis via Modulating Microbiota by Targeting IRF3 Activation International journal of molecular sciences 2023-09-07 [PMID: 37762104] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37724936" target="_blank" rel="nofollow"> Zhao, L;Song, R;Liu, Y; Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression European journal of immunology 2023-09-19 [PMID: 37724936] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37704580" target="_blank" rel="nofollow"> Shlykova, O;Izmailova, O;Kabaliei, 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(DHQ) ameliorates LPS-induced acute lung injury by regulating macrophage M2 polarization through IRF4/miR-132-3p/FBXW7 axis Pulmonary pharmacology & therapeutics 2023-08-28 [PMID: 37648017] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37633968" target="_blank" rel="nofollow"> Jiang, SY;Tian, T;Yao, H;Xia, XM;Wang, C;Cao, L;Hu, G;Du, RH;Lu, M; The cGAS-STING-YY1 axis accelerates progression of neurodegeneration in a mouse model of Parkinson's disease via LCN2-dependent astrocyte senescence Cell death and differentiation 2023-08-26 [PMID: 37633968] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37624261" target="_blank" rel="nofollow"> Das, B;Madhubala, D;Mahanta, S;Patra, A;Puzari, U;Khan, 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rel="nofollow"> Su, J;Chen, S;Xiao, J;Feng, Z;Hu, S;Su, Q;Chen, Q;Chen, D; Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis International journal of molecular sciences 2023-07-26 [PMID: 37569344] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37542992" target="_blank" rel="nofollow"> Hu, C;Zhang, B;Zhao, S; METTL3-mediated N6-methyladenosine modification stimulates mitochondrial damage and ferroptosis of kidney tubular epithelial cells following acute kidney injury by modulating the stabilization of MDM2-p53-LMNB1 axis European journal of medicinal chemistry 2023-11-05 [PMID: 37542992] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37503757" target="_blank" rel="nofollow"> Fan, H;Liu, S;Jiao, B;Liang, X; Low‑dose ionizing radiation attenuates high glucose‑induced hepatic apoptosis and immune factor release via modulation of a miR‑155‑SOCS1 axis Molecular medicine reports 2023-09-01 [PMID: 37503757] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37487070" target="_blank" rel="nofollow"> Bai, Y;Min, R;Chen, P;Mei, S;Deng, F;Zheng, Z;Jiang, C;Miao, R;Wu, Z;Zhang, P;Pan, Y;Lieberman, J;Liu, X; Disulfiram blocks inflammatory TLR4 signaling by targeting MD-2 Proceedings of the National Academy of Sciences of the United States of America 2023-08-01 [PMID: 37487070] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37460786" target="_blank" rel="nofollow"> Tawarayama, 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href="http://www.ncbi.nlm.nih.gov/pubmed/37429932" target="_blank" rel="nofollow"> Oishi, K;Yajima, Y;Yoshida, Y;Hagihara, H;Miyakawa, T;Higo-Yamamoto, S;Toyoda, A; Metabolic profiles of saliva in male mouse models of chronic sleep disorders induced by psychophysiological stress Scientific reports 2023-07-10 [PMID: 37429932] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37425960" target="_blank" rel="nofollow"> O'Brien, JG;Willis, AB;Long, AM;Kwon, J;Lee, G;Li, F;Page, PGT;Vo, AH;Hadhazy, M;Crosbie, RH;Demonbreun, AR;McNally, EM; The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix bioRxiv : the preprint server for biology 2023-06-30 [PMID: 37425960] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37417745" target="_blank" rel="nofollow"> Lin, JB;Mora, A;Wang, TJ;Santeford, A;Usmani, D;Ligon, MM;Mysorekar, IU;Apte, RS; Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages mBio 2023-07-07 [PMID: 37417745] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37406881" target="_blank" rel="nofollow"> Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S; Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells The ocular surface 2023-07-03 [PMID: 37406881] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37385574" target="_blank" rel="nofollow"> Lee, HS;Kwon, YJ;Seo, EB;Kim, SK;Lee, H;Lee, JT;Chang, PS;Choi, YJ;Lee, SH;Ye, SK; Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264.7 cells Journal of ethnopharmacology 2023-06-27 [PMID: 37385574] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37375032" target="_blank" rel="nofollow"> Chen, SY;Chu, CT;Yang, ML;Lin, JD;Wang, CT;Lee, CH;Lin, IC;Shiau, AL;Ling, P;Wu, CL; Amelioration of Murine Colitis by Attenuated Salmonella choleraesuis Encoding Interleukin-19 Microorganisms 2023-06-08 [PMID: 37375032] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a 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Life Sci., 2005-02-25;77(4):400-13. 2005-02-25 [PMID: 15894009] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15590467" target="_blank" rel="nofollow"> Thakur A, Barrett RP, McClellan S, Hazlett LD Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice. Curr. Eye Res., 2004-10-01;29(4):225-33. 2004-10-01 [PMID: 15590467] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15325513" target="_blank" rel="nofollow"> Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes. Comp. Immunol. Microbiol. Infect. Dis., 2004-11-01;27(6):393-411. 2004-11-01 [PMID: 15325513] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15308104" target="_blank" rel="nofollow"> Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15187118" target="_blank" rel="nofollow"> Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow. J. Immunol., 2004-06-15;172(12):7408-16. 2004-06-15 [PMID: 15187118] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15148335" target="_blank" rel="nofollow"> Hao Z, Hampel B, Yagita H, Rajewsky K T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis. J. Exp. Med., 2004-05-17;199(10):1355-65. 2004-05-17 [PMID: 15148335] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/14738872" target="_blank" rel="nofollow"> Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice. Exp. Mol. Pathol., 2004-02-01;76(1):76-81. 2004-02-01 [PMID: 14738872] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/14576054" target="_blank" rel="nofollow"> Pawlinski R, Pedersen B, Schabbauer G, Tencati M, Holscher T, Boisvert W, Andrade-Gordon P, Frank RD, Mackman N Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood, 2003-10-23;103(4):1342-7. 2003-10-23 [PMID: 14576054] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/14522418" target="_blank" rel="nofollow"> Rounioja S, Rasanen J, Glumoff V, Ojaniemi M, Makikallio K, Hallman M Intra-amniotic lipopolysaccharide leads to fetal cardiac dysfunction. A mouse model for fetal inflammatory response. Cardiovasc. Res., 2003-10-15;60(1):156-64. 2003-10-15 [PMID: 14522418] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12925700" target="_blank" rel="nofollow"> McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest., 2003-08-01;112(4):598-607. 2003-08-01 [PMID: 12925700] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12707345" target="_blank" rel="nofollow"> Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways. J. Immunol., 2003-05-01;170(9):4665-72. 2003-05-01 [PMID: 12707345] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12218100" target="_blank" rel="nofollow"> Miller G, 107331, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function. Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1alpha and the NAMPT-NAD+ pathway, 2002-09-15;169(6):2875-85. 2002-09-15 [PMID: 12218100] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/11449364" target="_blank" rel="nofollow"> Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls. Eur. J. Immunol., 2001-07-01;31(7):2104-15. 2001-07-01 [PMID: 11449364] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/10706861" target="_blank" rel="nofollow"> Shih CC, Hu MC, Hu J A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood, 2000-03-15;95(6):1957-66. 2000-03-15 [PMID: 10706861] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/9326224" target="_blank" rel="nofollow"> Liu F, Poursine-Laurent J, Wu HY, Link DC Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation. Blood, 1997-10-01;90(7):2583-90. 1997-10-01 [PMID: 9326224] (Mouse) </a></td> <td valign="top"></td> <td valign="top">Mouse</td> </tr><tr><td colspan="3" align="center"> <a class="pubs_showall">Show All 659 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a> </td></tr></tbody> </table> </div> </div> <a id="ReviewsSection"></a> <h2 class="greyHead2">Reviews for <span>IL-6 (M6000B) (0) </span></h2> <div class="ds_info"> There are no reviews for IL-6 (M6000B). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. <br/> <ul> <li>Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen</li> <li>Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen</li> </ul> <div class="align-right"> <a href="/reviews/M6000B"><button class="greybutton btn_width" name="novusreview">Submit a Review</button></a><br /> </div> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_protocols-faqs"> <a id="protocols-faqs"></a><h2 class="greyHead2">Product General Protocols</h2> <a id="protocols"></a> <div class="ds_info">Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars. <ul><li><a href="/support/support-by-application/elisa/protocol.html">ELISA</a></li><li><a href="/support/support-by-application.html">View all Protocols, Troubleshooting, Illustrated assays and Webinars.</a></li> </ul></div><h2 class="greyHead2">FAQs for IL-6 (M6000B). (Showing 1 - <span id="faqcnt">1</span> of 1 FAQs).</h2> <a id="faqs"></a> <ol id="faq_list"><li class="faqwrap "> <span class="faq_question">I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?</span> <ul class="faq_answer"> <li>We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.</li> </ul> </li></ol> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_supportresearch"> <a id="supportresearch"></a><table cellpadding="0" cellspacing="0"><tr></td></tr></table><h2 class="greyHead2">Additional IL-6 Products</h2> <a id="addtlalphaprods"></a> <div class="ds_info"> <div> <span style="display:none;">Array M6000B</span> <ul class="ds_noDotList"><li> <a href="/primary-antibodies/il-6">IL-6 Antibodies</a></li><li> <a href="/antibody-pairs/il-6">IL-6 Antibody Pair</a></li><li> <a href="/elisa-kits/il-6">IL-6 ELISA Kits</a></li><li> <a href="/lysates/il-6">IL-6 Lysate</a></li><li> <a href="/proteins/il-6">IL-6 Proteins</a></li><li> <a href="/proteins-and-enzymes/il-6">IL-6 Proteins and Enzymes</a></li><li> <a href="/elisas/il-6">IL-6 ELISAs</a></li></ul> </div> </div><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><h2 class="greyHead2">Blogs on IL-6. <span class="blogdiv">Showing 1-<span id="blogcnt">10</span> of 12 blog posts - <a class="blogs_showall">Show all blog posts</a>.</span></h2> <a id="blogsect"></a> <div class="ds_info"><a href="/antibody-news/tag/il-6">Check out the latest blog posts on IL-6</a>.</div> <div class="ds_info"> <table id="blogs_list_table"> <tbody> <tr class=" blogwrap "> <td> <strong><a href=""></a></strong><br/> <span>  <a href="">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href=""></a></strong><br/> <span>  <a href="">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/rest-in-peace-is-the-receptor-interacting-protein-rip-kinase-3-ripk3-a-protector-or-offender">Rest in Peace: Is the Receptor Interacting Protein (RIP) Kinase-3 (RIPK3) a Protector or Offender?</a></strong><br/> <span> By Jamshed Arslan, Pharm. D., PhD. Receptor interacting protein kinases (RIPKs) in necroptosisDeath is perhaps inevitable. Cell death can be programed and immunologically silent (apoptosis), unprogrammed and inflamm...  <a href="/antibody-news/rest-in-peace-is-the-receptor-interacting-protein-rip-kinase-3-ripk3-a-protector-or-offender">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href=""></a></strong><br/> <span>  <a href="">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/metabolic-syndrome-symptoms-and-associated-disease-states">Metabolic Syndrome: Symptoms and associated disease states</a></strong><br/> <span> By Jamshed Arslan, Pharm. D., PhD. What is metabolic syndrome?It was 1988 when, after decades of research, Dr. GM Reaven    of the Stanford University, CA, explained the relationship between four diseases:...  <a href="/antibody-news/metabolic-syndrome-symptoms-and-associated-disease-states">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/increased-wild-type-fus-levels-in-als-patients-lead-to-a-toxic-microenvironment-and-motor-neuron-neurodegeneration">Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration</a></strong><br/> <span> By Michalina Hanzel, PhDFUS mutations in Amyotrophic Lateral SclerosisFused in sarcoma (FUS) is a ribonucleoprotein that continuously shuttles between the nucleus and the cytoplasm to regulate pre-mRNA splicing, mRN...  <a href="/antibody-news/increased-wild-type-fus-levels-in-als-patients-lead-to-a-toxic-microenvironment-and-motor-neuron-neurodegeneration">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/the-role-of-hif-2-alpha-in-the-progression-and-therapy-of-clear-cell-renal-cell-carcinoma">The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma </a></strong><br/> <span>HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins. The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein ...  <a href="/antibody-news/antibodies/the-role-of-hif-2-alpha-in-the-progression-and-therapy-of-clear-cell-renal-cell-carcinoma">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/the-use-of-a-gfp-antibody-for-research-applications-in-transgenic-c-elegans-gfp-tagged-yeast-and-porcine-model">The use of a GFP antibody for research applications in transgenic C. elegans, GFP tagged yeast and porcine model</a></strong><br/> <span>GFP, or green fluorescent protein, is a chemiluminescent protein derived from Aequorea jellyfish that was first discovered by Osamu Shimomura. It was soon after established that the emission spectra of GFP was right around 509nm, or the ultraviol...  <a href="/antibody-news/antibodies/the-use-of-a-gfp-antibody-for-research-applications-in-transgenic-c-elegans-gfp-tagged-yeast-and-porcine-model">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/vegf-vascular-endothelial-growth-factor">VEGF: Vascular endothelial growth factor</a></strong><br/> <span>VEGF is homodimeric, disulfide-linked glycoprotein cytokine that serves as the ligand for FLT1 (VEGFR-1 receptor) and FLK1 (VEGFR-2 receptor) tyrosine kinases. It is a key modulator of physiological angiogenesis, vasculogenesis, and endothelial cell g...  <a href="/antibody-news/antibodies/vegf-vascular-endothelial-growth-factor">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/tlr2-i-can-recognize-many-foreign-pathogens">TLR2 - I can recognize many foreign pathogens!</a></strong><br/> <span>TLR2 is a member of the broad family of Toll-like receptors (TLR) that play an important role in pathogen recognition and innate immunity. TLRs, like other pattern recognition receptors (PRRs), recognize endogenous ligands released during cell or tiss...  <a href="/antibody-news/antibodies/tlr2-i-can-recognize-many-foreign-pathogens">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap hidden"> <td> <strong><a href="/antibody-news/antibodies/myd88-antibodies-for-il-signaling-and-immunity-research">MyD88 Antibodies for IL Signaling and Immunity Research</a></strong><br/> <span>The myeloid differentiation protein MyD88 (myeloid differentiation primary response protein) was originally identified and characterized as a primary upregulated response gene in interleukin-6 mediated myeloid differentiation. Now, MyD88 is known to b...  <a href="/antibody-news/antibodies/myd88-antibodies-for-il-signaling-and-immunity-research">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap hidden"> <td> <strong><a href="/antibody-news/antibodies/%e2%80%9cget-the-skinny%e2%80%9d-on-adiponectinleptin-2-antibodies-with-a-common-theme">"Get the skinny" on Adiponectin & Leptin Antibodies</a></strong><br/> <span>We at Novus Biologicals have an extensive antibody catalog covering lipid and metabolism research, including Adiponectin and leptin antibody products.Excess body fat is linked to many human diseases, including IRS (insulin resistance syndrome), type...  <a href="/antibody-news/antibodies/%e2%80%9cget-the-skinny%e2%80%9d-on-adiponectinleptin-2-antibodies-with-a-common-theme">Read full blog post.</a></span><br /><br /> </td> </tr></tbody> </table> </div><div class="ds_info"><span class="blogdiv">Showing 1-<span id="blogcnt">10</span> of 12 blog posts - <a 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</div><h2 class="greyHead2">Bioinformatics</h2> <div class="ds_info"> <a id="tab1bioinformatics"></a> <div> <table class="ds_list_right wide top"> <tr class="lined"> <td><strong>Gene Symbol</strong></td> <td><a href="/gene-name/Il6">Il6</a></td> </tr></table> </div> </div> </div> </div><div class="clear"></div><noscript><form autocomplete="off" action="/products/mouse-il-6-quantikine-elisa-kit-2-plate_m6000b" method="post" id="et-add-multiple-to-cart-form" accept-charset="UTF-8"><div><table class="sticky-enabled"> <thead><tr><th>Size</th><th>Price</th> </tr></thead> <tbody> <tr class="odd"><td><div class="atc_size" title="catalog # M6000B-1">1 Kit <br /> (1 Plate)</div><div data-msg='' class="atc_catnum">M6000B-1</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">4-6 Business Days</td> </tr> <tr class="odd"><td><div class="atc_size" 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Mouse IL-6 Quantikine ELISA Kit, 2 Plate (M6000B): Novus Biologicals