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padding-bottom: ;" > <div class="coh-container gls-container gls-container-small" > <div class="coh-container ssa-component coh-component ssa-component-instance-790a036e-cec6-422b-bb1c-9afdebc37dc6 coh-component-instance-790a036e-cec6-422b-bb1c-9afdebc37dc6 coh-heading-component" data-lift-slot > <div class="coh-inline-element gls-pre-heading gls-h4 gls-text-muted gls-margin-xsmall-bottom gls-text-center"></div> <h2 class="coh-heading gls-text-primary gls-text-uppercase gls-text-center gls-margin-medium-bottom" > <span class="coh-inline-element">Ambitious Philanthropists Accelerating Research and Igniting Innovation</span> </h2> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-c8484e0e-2098-4d4a-b855-bbcf3f26af71 coh-component-instance-c8484e0e-2098-4d4a-b855-bbcf3f26af71 " data-lift-slot > <div class="coh-wysiwyg" > <p><span>The University of Utah Health Philanthropic Partners, a group comprised of ambitious philanthropists who wish to accelerate research at University of Utah Health, have been formed to ignite innovation in today鈥檚 challenging funding climate. Strategically targeting vital areas of need with pooled resources and motivated by the pursuit of discovery, </span>the Philanthropic Partners will propel a straightforward idea that forms the bedrock of exceptional achievement: empowering the most brilliant minds to push the boundaries of their abilities and venture into uncharted territories will pave the way for a brighter and more promising tomorrow.<span> </span></p> </div> </div> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-e1366347-2e7e-4ae1-9083-d82886c79aaf coh-component-instance-e1366347-2e7e-4ae1-9083-d82886c79aaf" data-lift-slot > <div class="coh-container gls-section gls-section-default default-size" style="padding-top: var(--section-xsmall-padding-vertical); padding-bottom: var(--section-padding-vertical);" > <div class="coh-container gls-container gls-container-small" > <div class="coh-container ssa-component coh-component ssa-component-instance-aae2d1ce-d7b8-4030-91ec-c6c2cb256b5c coh-component-instance-aae2d1ce-d7b8-4030-91ec-c6c2cb256b5c" data-lift-slot > <div class="coh-container gls-container gls-margin-medium-bottom" > <div class="coh-container gls-grid-small gls-child-width-1-2@m gls-child-width-1-2@s" gls-height-match="target: .gls-card" gls-grid > <div class="coh-container ssa-component coh-component ssa-component-instance-5d4694d5-5d1b-4f70-b470-6ec3f5944281 coh-component-instance-5d4694d5-5d1b-4f70-b470-6ec3f5944281" data-lift-slot > <div class="coh-container gls-position-relative gls-card-cover-container " > <div class="coh-container gls-card gls-flex gls-flex-column no-border gls-card-shadow gls-text-left gls-card-default " > <div class="coh-container gls-card-media-top gls-cover-container" > <picture> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 2400px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 1599px) and (max-width: 2399px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 1199px) and (max-width: 1598px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 959px) and (max-width: 1198px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 639px) and (max-width: 958px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" media="(min-width: 0px) and (max-width: 638px)" type="image/jpeg"> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="/sites/g/files/zrelqx386/files/media/images/2024/UUHC_220719_5022-3.jpg" alt="Rachel Hess " /> </picture> </div> <div class="coh-container gls-card-body" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom " > Rachel Hess, MD, MS </h3> <p class="coh-paragraph gls-text-meta gls-margin-remove-top " >AVP for Research</p> <div class="coh-wysiwyg gls-margin-top " > <p><span>Dr. Rachel Hess founded the Philanthropic Partners Group to catalyze breakthroughs and accelerate health sciences research. As the Health Sciences AVP for Research, Dr. Hess plays a pivotal role in shaping the research landscape at the University of Utah Health. Dr. Hess is a distinguished physician, researcher, and visionary leader. Knowing that breakthroughs often emerge at the intersection of diverse expertise, she fosters a collaborative environment and encourages innovative thinking and calculated risk-taking.</span></p> </div> </div> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-59b68ed1-a47e-47de-82c8-33ac2c48be7e coh-component-instance-59b68ed1-a47e-47de-82c8-33ac2c48be7e" data-lift-slot > <div class="coh-container gls-position-relative gls-card-cover-container " > <div class="coh-container gls-card gls-flex gls-flex-column no-border gls-card-shadow gls-text-left gls-card-default " > <div class="coh-container gls-card-media-top gls-cover-container" > <picture> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 2400px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 1599px) and (max-width: 2399px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 1199px) and (max-width: 1598px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 959px) and (max-width: 1198px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 639px) and (max-width: 958px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" media="(min-width: 0px) and (max-width: 638px)" type="image/jpeg"> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="/sites/g/files/zrelqx386/files/media/images/2024/UUH_230530_5185-2.jpg" alt="Mario Capecchi, PhD" /> </picture> </div> <div class="coh-container gls-card-body" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom " > Mario Capecchi, PhD </h3> <p class="coh-paragraph gls-text-meta gls-margin-remove-top " >Scientific Advisor</p> <div class="coh-wysiwyg gls-margin-top " > <p><span>Dr. Mario Capecchi serves as a Scientific Advisor to the Philanthropic Partners Group. Dr. Capecchi鈥檚 revolutionary research involving creating knockout mice, where specific genes could be turned off led to him receiving the Nobel Prize in Physiology or Medicine in 2007. Dr. Capecchi brings unparalleled insights into cutting-edge research and scientific advancements. His strategic guidance can help the group identify high-impact areas for philanthropic investments.</span></p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-8dfdd2d6-9884-473e-a825-05023bf82834 coh-component-instance-8dfdd2d6-9884-473e-a825-05023bf82834" data-lift-slot > <section class="coh-container gls-section-default gls-cover-container " > <div class="coh-container gls-section gls-flex gls-hack-ios-disable-parallax ssa-instance-04b1fc1abec405fab6bcd8ca6b5166c4 coh-ce-cpt_text_over_parallax_backgro_0-52c56c35" style="min-height: 30vh" > <div class="coh-container gls-overlay-primary gls-position-cover" > </div> <div class="coh-container gls-container gls-flex gls-width-expand" > <div class="coh-container gls-grid gls-width-expand gls-grid-column-collapse gls-flex-self-middle gls-flex-center gls-text-center" > <div class="coh-column coh-col-ps coh-visible-xl coh-col-xl-8" > <span class="coh-inline-element gls-light"> <p class="coh-paragraph gls-h1 gls-text-shadow" >Accelerate Research</p> <div class="coh-wysiwyg" > </div> </span> </div> </div> </div> </div> </section> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-1fa95003-15db-478a-bc8d-0fea124727ef coh-component-instance-1fa95003-15db-478a-bc8d-0fea124727ef" data-lift-slot > <div class="coh-container gls-section gls-section-default default-size" style="padding-top: var(--section-padding-vertical); padding-bottom: var(--section-large-padding-vertical);" > <div class="coh-container gls-container default-width" > <div class="coh-container ssa-component coh-component ssa-component-instance-9634ff5f-23fb-4023-9e78-d16f1c9972c3 coh-component-instance-9634ff5f-23fb-4023-9e78-d16f1c9972c3" data-lift-slot > <div class="coh-container gls-card gls-card-default no-border ssa-instance-0a58296473bde5aa8a252badf6a27616 coh-ce-cpt_custom_card_component-50d3800d" > <div class="coh-container gls-card-media-top" > <picture> <source srcset="" media="(min-width: 2400px)" type=""> <source srcset="" media="(min-width: 1599px) and (max-width: 2399px)" type=""> <source srcset="" media="(min-width: 1199px) and (max-width: 1598px)" type=""> <source srcset="" media="(min-width: 959px) and (max-width: 1198px)" type=""> <source srcset="" media="(min-width: 639px) and (max-width: 958px)" type=""> <source srcset="" media="(min-width: 0px) and (max-width: 638px)" type=""> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="" alt /> </picture> </div> <div class="coh-container gls-card-body" > <div class="coh-container gls-grid-small gls-flex-middle gls-grid" gls-grid > <div class="coh-container gls-width-expand" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom" > Philanthropic Partners </h3> </div> </div> <div class="coh-container gls-margin" > <div class="coh-wysiwyg" > <p><span>The Philanthropic Partners invite proposals from researchers with inventive and innovative ideas who are seeking seed funding to accelerate breakthroughs and test new ideas that are not yet viable for traditional funding mechanisms. The goal of this initiative is to ignite high-risk, potentially high-reward research programs that address critical societal issues and foster innovation, discovery, and collaboration.</span></p><p><span>Philanthropic Partners offer insights and perspectives from varied backgrounds including business, law, engineering, marketing, and more. While our partners come from unique backgrounds, the groups' collective excitement for igniting discovery, innovation, and curiosity in health sciences through philanthropy unite them into a powerful, action-oriented group of change makers.  </span></p><p><span>The Philanthropic Partners Group meets twice a year, once to hear presentations from researchers seeking seed funding and once to receive updates from funded research projects.</span></p> </div> </div> </div> </div> </div> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-cc54ba78-606d-4b34-86f4-ee27a5d1bd42 coh-component-instance-cc54ba78-606d-4b34-86f4-ee27a5d1bd42" > <section class="coh-container gls-section-default " > <div class="coh-container gls-cover-container" > <div class="coh-video-background coh-video-background-center" gls-cover> <video class="coh-video-background-inner" autoplay loop muted playsinline poster="http://cfvod.kaltura.com/p/797802/sp/79780200/thumbnail/entry_id/1_dev3j366/version/100021" src="https://www.kaltura.com/p/797802/sp/0/playManifest/entryId/1_dev3j366/format/url/flavorParamId/0/video.mp4" data-coh-video-background='{"pauseWhenHidden" : 1,"disableOnTouch" : false}'> </video> </div> <div class="coh-container gls-section gls-section-small" > <div class="coh-container gls-container" > <div class="coh-container gls-flex gls-flex-right" > <div class="coh-container gls-tile gls-width-1-3@l gls-width-1-2@s gls-tile-default " > <div class="coh-container gls-margin-medium" > <h2 class="coh-heading gls-text-primary gls-text-semibold gls-text-uppercase gls-margin-remove" > Interested in joining the Philanthropic Partners Group? </h2> </div> <div class="coh-wysiwyg" > <p><strong>Contact: Emily Blake </strong> <br>Director of Advancement, AVP for Research Office<br><a href="mailto:emily.blake@utah.edu聽">emily.blake@utah.edu </a><br>(208) 447-9379<o:p></o:p></p> </div> <a href="/staff/emily-blake" class="coh-link gls-margin-medium gls-button gls-button-primary" target="_self" > Contact Us for More Details </a> </div> </div> </div> </div> </div> </section> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-e80710da-b076-43cb-8510-c63b2d4c6a37 coh-component-instance-e80710da-b076-43cb-8510-c63b2d4c6a37" data-lift-slot > <div class="coh-container gls-section gls-section-default default-size" style="padding-top: var(--section-large-padding-vertical); padding-bottom: var(--section-padding-vertical);" > <div class="coh-container gls-container default-width" > <div class="coh-container ssa-component coh-component ssa-component-instance-65adf526-d033-48e6-bbd8-e5196d85c17b coh-component-instance-65adf526-d033-48e6-bbd8-e5196d85c17b coh-heading-component" data-lift-slot > <div class="coh-inline-element gls-pre-heading gls-h4 gls-text-muted gls-margin-xsmall-bottom gls-text-center"></div> <h2 class="coh-heading gls-h3 gls-text-secondary gls-heading-line gls-text-uppercase gls-text-center gls-margin-medium-bottom" > <span class="coh-inline-element">Funded Projects</span> </h2> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-23a4b265-5ada-42bd-8794-90528e45590d coh-component-instance-23a4b265-5ada-42bd-8794-90528e45590d" data-lift-slot > <div class="coh-container gls-container gls-margin-medium-bottom" > <div class="coh-container gls-grid-small gls-child-width-1-3@m gls-child-width-1-2@s" gls-height-match="target: .gls-card" gls-grid > <div class="coh-container ssa-component coh-component ssa-component-instance-2fc4557f-a5d2-433e-9906-399be7ec539b coh-component-instance-2fc4557f-a5d2-433e-9906-399be7ec539b" data-lift-slot > <div class="coh-container gls-card gls-card-default gls-border ssa-instance-fa6ab687f5c6909a512542d0b1fbe956 coh-ce-cpt_custom_card_component-50d3800d" > <div class="coh-container gls-card-media-top" > <picture> <source srcset="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=q-JBZbWb" media="(min-width: 2400px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_desktop/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=1t-WBlXy" media="(min-width: 1599px) and (max-width: 2399px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_laptop/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=zO8pfmbz" media="(min-width: 1199px) and (max-width: 1598px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_tablet/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=FSZupphy" media="(min-width: 959px) and (max-width: 1198px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=ba-UofMX" media="(min-width: 639px) and (max-width: 958px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=ba-UofMX" media="(min-width: 0px) and (max-width: 638px)" type="image/jpeg"> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2024/UUH_240223_5035.jpg?h=95294a2a&itok=q-JBZbWb" alt="Keren Hilgendorf, PhD, Huntsman Cancer Institute; Biochemistry Portrait" /> </picture> </div> <div class="coh-container gls-card-body" > <div class="coh-container gls-grid-small gls-flex-middle gls-grid" gls-grid > <div class="coh-container gls-width-expand" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom" > Harnessing Lean Fat Cells to Kill Breast Cancer </h3> <p class="coh-paragraph gls-text-meta gls-margin-remove-top" >Keren Hilgendorf, PhD, Huntsman Cancer Institute; Biochemistry </p> </div> </div> <div class="coh-container gls-margin" > <div class="coh-wysiwyg" > <p><span>Hilgendorf is researching why obesity raises the risk of breast cancer. Her early findings indicate that lean fat cells鈥攚hich contain a type of fatty acid found more often in breast tissue of non-obese individuals鈥攕low tumor growth in mice. This project will test whether the fatty acid can also inhibit growth of breast cancer cells from patients. The finding could one day lead to new approaches for preventing and treating breast cancer.</span></p> </div> </div> </div> <div class="coh-container gls-card-footer" > <a href="https://medicine.utah.edu/faculty/keren-i-hilgendorf" class="coh-link gls-link show-focus" target="_self" > Profile </a> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-d6948462-2bb3-4469-b5c9-58f3815e23e2 coh-component-instance-d6948462-2bb3-4469-b5c9-58f3815e23e2" data-lift-slot > <div class="coh-container gls-card gls-card-default gls-border ssa-instance-a1815c395ff5eee34678d34bef503dc8 coh-ce-cpt_custom_card_component-50d3800d" > <div class="coh-container gls-card-media-top" > <picture> <source srcset="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=0Q6Mbd5c" media="(min-width: 2400px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_desktop/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=Eex-YmJi" media="(min-width: 1599px) and (max-width: 2399px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_laptop/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=7WV6Ot4e" media="(min-width: 1199px) and (max-width: 1598px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_tablet/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=fIene4KW" media="(min-width: 959px) and (max-width: 1198px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=3d6oPpxT" media="(min-width: 639px) and (max-width: 958px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=3d6oPpxT" media="(min-width: 0px) and (max-width: 638px)" type="image/jpeg"> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2022/rahimpour_shervin.jpg?h=80a6970f&itok=0Q6Mbd5c" alt="Shervin Rahimpour, MD, Neurosurgery " /> </picture> </div> <div class="coh-container gls-card-body" > <div class="coh-container gls-grid-small gls-flex-middle gls-grid" gls-grid > <div class="coh-container gls-width-expand" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom" > From Blind to Precise: Life-Saving Accuracy in Brain Surgery </h3> <p class="coh-paragraph gls-text-meta gls-margin-remove-top" >Shervin Rahimpour, MD, Neurosurgery </p> </div> </div> <div class="coh-container gls-margin" > <div class="coh-wysiwyg" > <p><span>To relieve pressure from the brain after a traumatic brain injury, neurosurgeons use a device called an external ventricular drain (EVD). When this procedure is done at the bedside, it is often done imprecisely without the use of any navigation, putting the patient at risk for further injury. A team led by Rahimpour seeks to improve this procedure by developing a device that uses ultrasound technology and advanced 3D imaging to give a real-time view of the brain as the drain is inserted. The advance aims to make these procedures faster, safer, and more precise with potential application in other critical procedures such as brain biopsies and heart surgeries.</span></p> </div> </div> </div> <div class="coh-container gls-card-footer" > <a href="https://healthcare.utah.edu/find-a-doctor/shervin-rahimpour" class="coh-link gls-link show-focus" target="_self" > Profile </a> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-b33d1dab-e4a4-48ea-9502-0634750349b9 coh-component-instance-b33d1dab-e4a4-48ea-9502-0634750349b9" data-lift-slot > <div class="coh-container gls-card gls-card-default gls-border ssa-instance-9f8200d87b1f5ca85e369f01cc805e56 coh-ce-cpt_custom_card_component-50d3800d" > <div class="coh-container gls-card-media-top" > <picture> <source srcset="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=soDhH0o6" media="(min-width: 2400px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_desktop/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=xOUYblfg" media="(min-width: 1599px) and (max-width: 2399px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_laptop/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=PUgxvpJa" media="(min-width: 1199px) and (max-width: 1598px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_tablet/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=Rz5YgHbA" media="(min-width: 959px) and (max-width: 1198px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=mn-y1R6w" media="(min-width: 639px) and (max-width: 958px)" type="image/jpeg"> <source srcset="/sites/g/files/zrelqx386/files/styles/square_phone/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=mn-y1R6w" media="(min-width: 0px) and (max-width: 638px)" type="image/jpeg"> <img class="coh-image coh-image-responsive-xl coh-image-responsive-lg coh-image-responsive-md coh-image-responsive-sm coh-image-responsive-ps coh-image-responsive-xs" src="/sites/g/files/zrelqx386/files/styles/square_wide/public/media/images/2024/Justin%20Bosch.jpg?h=ebd84c35&itok=soDhH0o6" alt="Justin Bosch, PhD, Human Genetics " /> </picture> </div> <div class="coh-container gls-card-body" > <div class="coh-container gls-grid-small gls-flex-middle gls-grid" gls-grid > <div class="coh-container gls-width-expand" > <h3 class="coh-heading gls-card-title gls-margin-remove-bottom" > A New AI-based Approach for Disease Diagnosis and Personalized Medicine </h3> <p class="coh-paragraph gls-text-meta gls-margin-remove-top" >Justin Bosch, PhD, Human Genetics </p> </div> </div> <div class="coh-container gls-margin" > <div class="coh-wysiwyg" > <p><span>A major challenge in genomic medicine is determining which of the millions of changes鈥攐r variants鈥攊n our DNA code lead to disease. Missense variants change how proteins are made, potentially affecting their ability to work together with other proteins to carry out important functions in our body鈥檚 cells. However, 98% of missense variants have not yet been classified as harmful or benign, hindering disease diagnosis. Using an advanced AI tool called AlphaFold, Bosch and team will predict the impact of missense variants on hormone-receptor interactions, which play critical roles in conditions like diabetes and obesity. The new data could improve disease diagnosis and lead to new therapeutics.</span></p> </div> </div> </div> <div class="coh-container gls-card-footer" > <a href="https://www.genetics.utah.edu/research/justin-a-bosch" class="coh-link gls-link show-focus" target="_self" > Profile </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-8e1ce26d-37a5-4a88-8d45-58bf07d8d83a coh-component-instance-8e1ce26d-37a5-4a88-8d45-58bf07d8d83a" data-lift-slot > <div class="coh-container gls-section gls-section-muted default-size" style="padding-top: ; padding-bottom: ;" > <div class="coh-container gls-container gls-container-small" > <div class="coh-container ssa-component coh-component ssa-component-instance-0957e16e-d433-426d-ad7c-5fb8c15702a1 coh-component-instance-0957e16e-d433-426d-ad7c-5fb8c15702a1 coh-heading-component" data-lift-slot > <div class="coh-inline-element gls-pre-heading gls-h4 gls-text-muted gls-margin-xsmall-bottom gls-text-center"></div> <h2 class="coh-heading gls-h3 gls-text-secondary gls-heading-line gls-text-uppercase gls-text-center gls-margin-medium-bottom" > <span class="coh-inline-element">U of U Health investigators learn how you can connect with potential funders to advance your research.</span> </h2> </div> <div class="coh-container ssa-component coh-component ssa-component-instance-a66d85ae-8fca-444f-9da3-5bfeb14e7d14 coh-component-instance-a66d85ae-8fca-444f-9da3-5bfeb14e7d14" data-lift-slot > <div class="coh-container gls-text-center gls-margin-small-top gls-margin-large-bottom coh-ce-cpt_standard_button_component-c5ddda05" > <a href="" class="coh-link gls-button gls-button-secondary default-size default-width" target="_self" > RFP on Competition Space </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> </main> </div> </div> <footer role="contentinfo"> <div id="region--footer" class="region region-footer"> <div 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