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*/ body.search .site-inner { padding-left: unset; padding-right: unset; } </style> </head> <body class="archive category category-facility category-7 content-sidebar genesis-breadcrumbs-hidden">  <div id="prestitial" style="opacity: 0;"> <div id="prestitial-overlay"></div> <div id="prestitial-grid"> <div class="prestitial-logo"> <div class="title-area"> <h1 class="site-title"> <a href="#"><img src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2022/10/pharma-logo.png"></a></h1> </div> </div> <div class="close-cta"> Continue to Site <i class="fa fa-arrow-right"></i> </div> <div id="prestitial-banner"></div> </div> </div>  <div id="body-wrapper" style="opacity: 0;"> <div class="site-container"><header class="site-header"><div class="wrap"><div class="title-area"><p class="site-title"><a href="https://www.pharmaceuticalprocessingworld.com/">Pharmaceutical Processing World</a></p></div><div class="widget-area header-widget-area"><section id="custom_html-2" 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class="menu-item search"><a href="#" class="search-toggle"><i class="icon-search"></i></a></li></ul></div></nav><div class="archive-intro"><div class="wrap"><h1 class="archive-title"><span>Facility</span></h1></div></div><div class="site-inner"><div class="wrap"><div class="content-sidebar-wrap"><main class="content"><article class="type-post entry has-post-thumbnail" aria-label="Sanofi to invest €40 million to boost antibody production in France"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">November 19, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/sanofi-to-invest-e40-million-to-boost-antibody-production-in-france/">Sanofi to invest €40 million to boost antibody production in France</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/sanofi-to-invest-e40-million-to-boost-antibody-production-in-france/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2022/03/Sanofi-Logo-Video-Still-2-268x170.jpg" class="alignleft post-image entry-image wp-image-15160" alt="Sanofi logo" decoding="async" /></a><p>Sanofi recently announced that it is investing €40 million in its Lyon Gerland bioproduction site as it seeks to bolster its position in the immunology space. The investment will support production in France of the transplant drug Thymoglubulin, including €25 million toward developing and manufacturing a second-generation version of the drug. The remaining €15 million…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="How biometric ID is boosting security and efficiency in pharma manufacturing"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">November 14, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/how-biometric-id-is-boosting-security-and-efficiency-in-pharma-manufacturing/">How biometric ID is boosting security and efficiency in pharma manufacturing</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/how-biometric-id-is-boosting-security-and-efficiency-in-pharma-manufacturing/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2024/11/ARISTA-Wearable-Identity-Authentication-268x170.jpg" class="alignleft post-image entry-image wp-image-16497" alt="This is an Arista Corp. marketing image showing pharmaceutical workers using Nymi Bands and their biometric ID." decoding="async" loading="lazy" /></a><p>A maker of pharma manufacturing workstations says wearable biometric ID products are solving a security and efficiency challenge. Traditionally, pharmaceutical manufacturers have used a complex patchwork of access points, workstations, and tools, according to Fremont, California–based Arista Corp. Think badges, passwords and more, with the potential for someone other than the intended operator to gain…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="Otsuka partners with ICU Medical to enter U.S. IV products market"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">November 13, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/otsuka-partners-with-icu-medical-to-enter-u-s-iv-products-market/">Otsuka partners with ICU Medical to enter U.S. IV products market</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/otsuka-partners-with-icu-medical-to-enter-u-s-iv-products-market/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2024/11/Otsuka-ICU-Medical-268x170.png" class="alignleft post-image entry-image wp-image-16495" alt="These are the logos of Otsuka Medical and ICU Medical." decoding="async" loading="lazy" /></a><p>Otsuka Holdings will pay ICU Medical (Nasdaq: ICUI) an upfront payment of $200 million as part of a joint venture to enter the U.S. IV products market, which has been facing hurricane-related shortages this fall. The partnership — which involves ICU Medical providing commercial services for Otsuka’s Otsuka Pharmaceutical Factory (OPF) subsidiary — also includes…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="MilliporeSigma invests $76M to expand cancer therapy manufacturing"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/swhooley/" class="entry-author-link" rel="author"><span class="entry-author-name">Sean Whooley</span></a></span> | <time class="entry-time">October 31, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/milliporesigma-invests-76m-to-expand-cancer-therapy-manufacturing/">MilliporeSigma invests $76M to expand cancer therapy manufacturing</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/milliporesigma-invests-76m-to-expand-cancer-therapy-manufacturing/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2024/10/MilliporeSigma-ADC-manufacturing-expansion-1-268x170.jpg" class="alignleft post-image entry-image wp-image-16483" alt="MilliporeSigma ADC manufacturing expansion (1)" decoding="async" loading="lazy" /></a><p>MilliporeSigma, Merck KGaA’s U.S. and Canada Life Science business, announced a $76 million expansion of its ADC manufacturing capabilities and capacity. The company is expanding the capacity at its Bioconjugation Center of Excellence facility in St. Louis. This investment triples existing capacity and enhances the company’s contract development and manufacturing organization (CDMO) offering. MilliporeSigma said…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="PharmaLogic opens new radiopharmaceutical production plant in Utah"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/swhooley/" class="entry-author-link" rel="author"><span class="entry-author-name">Sean Whooley</span></a></span> | <time class="entry-time">October 18, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/pharmalogic-opens-radiopharmaceutical-production-plant-utah/">PharmaLogic opens new radiopharmaceutical production plant in Utah</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/pharmalogic-opens-radiopharmaceutical-production-plant-utah/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2024/10/PharmaLogic-268x170.jpg" class="alignleft post-image entry-image wp-image-16477" alt="PharmaLogic" decoding="async" loading="lazy" /></a><p>PharmaLogic announced today that it opened a new radiopharmaceutical production and research facility in Salt Lake City. The new state-of-the-art facility marks “a major step forward” in the CDMO’s mission to deliver diagnostic and therapeutic radiopharmaceuticals to patients across North America, according to a news release. PharmaLogic said it chose to establish the facility in…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="J&J invest $2B to build new manufacturing facility in North Carolina"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/dkirsh/" class="entry-author-link" rel="author"><span class="entry-author-name">Danielle Kirsh</span></a></span> | <time class="entry-time">October 7, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/jj-invest-2b-to-build-new-manufacturing-facility-in-north-carolina/">J&J invest $2B to build new manufacturing facility in North Carolina</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/jj-invest-2b-to-build-new-manufacturing-facility-in-north-carolina/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2024/05/Johnson-Johnson-logo-268x170.png" class="alignleft post-image entry-image wp-image-16345" alt="This is the logo of Johnson & Johnson." decoding="async" loading="lazy" /></a><p>Johnson & Johnson recently announced plans to invest more than $2 billion in a new manufacturing facility in North Carolina. The company plans to build a state-of-the-art biologics manufacturing facility in Wilson, North Carolina, to expand the production of its pipeline of innovative biologics. The expansion supports J&J’s broader plan to advance more than 70…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="Roche opens pharma R&D facility in Switzerland"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/dkirsh/" class="entry-author-link" rel="author"><span class="entry-author-name">Danielle Kirsh</span></a></span> | <time class="entry-time">September 30, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/roche-opens-pharma-rd-facility-in-switzerland/">Roche opens pharma R&D facility in Switzerland</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/roche-opens-pharma-rd-facility-in-switzerland/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/04/roche-7x4-1-268x170.png" class="alignleft post-image entry-image wp-image-14371" alt="Roche" decoding="async" loading="lazy" /></a><p>Roche recently announced it opened its latest Pharma Research and Early Development (pRED) Center in Basel Switzerland. The new facility is equipped with cutting-edge technologies and houses around 1,000 laboratory and office workspaces, according to the company. It is located at the company’s global headquarters and brings together teams of scientists and researchers to accelerate…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="Lilly expands manufacturing footprint in Ireland"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">September 17, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/lilly-expands-manufacturing-footprint-in-ireland/">Lilly expands manufacturing footprint in Ireland</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/lilly-expands-manufacturing-footprint-in-ireland/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1-268x170.jpg" class="alignleft post-image entry-image wp-image-14204" alt="This is the logo of Eli Lilly." decoding="async" loading="lazy" /></a><p>Eli Lilly and Co. recently announced that it’s spending $1 billion to expand its Limerick, Ireland, manufacturing site. The goal of the expansion, announced Sept. 12, is to increase the production of biologic active ingredients, including those for the company’s recently approved treatment for early symptomatic Alzheimer’s disease. The company announced in July that the…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="Eugia Pharma receives OAI classification from FDA following sterile production inspections"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/dkirsh/" class="entry-author-link" rel="author"><span class="entry-author-name">Danielle Kirsh</span></a></span> | <time class="entry-time">August 20, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/eugia-pharma-receives-oai-classification-from-fda-following-sterile-production-inspections/">Eugia Pharma receives OAI classification from FDA following sterile production inspections</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/eugia-pharma-receives-oai-classification-from-fda-following-sterile-production-inspections/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/04/FDA-logo-new-268x170.png" class="alignleft post-image entry-image wp-image-14344" alt="FDA logo" decoding="async" loading="lazy" /></a><p>Eugia Pharma Specialties’ manufacturing hub in India has received an FDA warning letter based on inspections of its facility. The new warning letter is tied to previous warnings about the company’s Unit III Formulation manufacturing facility. The unit makes terminally sterilized products. Eugia’s Hyderabad, India-based facility received an official action indicated (OAI) status notice in…</p> </div><footer class="entry-footer"></footer></article><article class="type-post entry has-post-thumbnail" aria-label="Pfizer opens expanded APIs plant in Singapore"><header class="entry-header"><p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">August 6, 2024</time></p><h2 class="entry-title"><a class="entry-title-link" rel="bookmark" href="https://www.pharmaceuticalprocessingworld.com/pfizer-opens-expanded-apis-plant-in-singapore/">Pfizer opens expanded APIs plant in Singapore</a></h2> </header><div class="entry-content"><a class="entry-image-link" href="https://www.pharmaceuticalprocessingworld.com/pfizer-opens-expanded-apis-plant-in-singapore/" aria-hidden="true" tabindex="-1"><img width="268" height="170" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/05/Pfizer-2-1-268x170.png" class="alignleft post-image entry-image wp-image-14451" alt="This is the logo of Pfizer." decoding="async" loading="lazy" /></a><p>Pfizer recently opened an extension of its highly automated active pharmaceutical ingredient (API) manufacturing facility in Tuas Biomedical Park in Singapore. The 429,000 ft2 expansion cost SGD $1 billion (U.S. $745 million), according to a July 23 news release from the Singapore Economic Development Board. Pfizer has passed final performance qualification checks at the facility…</p> </div><footer class="entry-footer"></footer></article><div class="archive-pagination pagination"><div class="pagination-next alignright"><a href="https://www.pharmaceuticalprocessingworld.com/category/facility/page/2/" class="button">Next ></a></div></div></main><aside class="sidebar sidebar-primary widget-area" role="complementary" aria-label="Primary Sidebar"><section id="custom_html-11" class="widget_text widget widget_custom_html"><div class="widget_text widget-wrap"><div class="textwidget custom-html-widget"><center> <div style="display: flex; flex-direction: column; justify-content: center; width: 300px;"> <div align="center"><a href="https://www.pharmaceuticalprocessingworld.com/sign-up-for-the-pharmaceutical-processing-enewsletter/" target="_blank"><img src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2023/12/PharmaceuticalProcessing-300x100-1.jpg" alt=“ppw newsletter”></a></div> 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e({values:Mr(t,e.normalizeUnit),loc:xi.fromObject(n),conversionAccuracy:n.conversionAccuracy})},e.fromDurationLike=function(t){if(or(t))return e.fromMillis(t);if(e.isDuration(t))return t;if("object"==typeof t)return e.fromObject(t);throw new Fn("Unknown duration argument "+t+" of type "+typeof t)},e.fromISO=function(t,n){var r=Mi(t,[Pi,Yi])[0];return r?e.fromObject(r,n):e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.fromISOTime=function(t,n){var r=Mi(t,[ji,oo])[0];return r?e.fromObject(r,n):e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.invalid=function(t,n){if(void 0===n&&(n=null),!t)throw new Fn("need to specify a reason the Duration is invalid");var r=t instanceof Hr?t:new Hr(t,n);if(li.throwOnInvalid)throw new In(r);return new e({invalid:r})},e.normalizeUnit=function(e){var t={year:"years",years:"years",quarter:"quarters",quarters:"quarters",month:"months",months:"months",week:"weeks",weeks:"weeks",day:"days",days:"days",hour:"hours",hours:"hours",minute:"minutes",minutes:"minutes",second:"seconds",seconds:"seconds",millisecond:"milliseconds",milliseconds:"milliseconds"}[e?e.toLowerCase():e];if(!t)throw new Cn(e);return t},e.isDuration=function(e){return e&&e.isLuxonDuration||!1};var t=e.prototype;return t.toFormat=function(e,t){void 0===t&&(t={});var n=gn({},t,{floor:!1!==t.round&&!1!==t.floor});return this.isValid?Ur.create(this.loc,n).formatDurationFromString(this,e):"Invalid Duration"},t.toHuman=function(e){var t=this;void 0===e&&(e={});var n=ho.map((function(n){var r=t.values[n];return ir(r)?null:t.loc.numberFormatter(gn({style:"unit",unitDisplay:"long"},e,{unit:n.slice(0,-1)})).format(r)})).filter((function(e){return e}));return this.loc.listFormatter(gn({type:"conjunction",style:e.listStyle||"narrow"},e)).format(n)},t.toObject=function(){return this.isValid?gn({},this.values):{}},t.toISO=function(){if(!this.isValid)return null;var e="P";return 0!==this.years&&(e+=this.years+"Y"),0===this.months&&0===this.quarters||(e+=this.months+3*this.quarters+"M"),0!==this.weeks&&(e+=this.weeks+"W"),0!==this.days&&(e+=this.days+"D"),0===this.hours&&0===this.minutes&&0===this.seconds&&0===this.milliseconds||(e+="T"),0!==this.hours&&(e+=this.hours+"H"),0!==this.minutes&&(e+=this.minutes+"M"),0===this.seconds&&0===this.milliseconds||(e+=yr(this.seconds+this.milliseconds/1e3,3)+"S"),"P"===e&&(e+="T0S"),e},t.toISOTime=function(e){if(void 0===e&&(e={}),!this.isValid)return null;var t=this.toMillis();if(t<0||t>=864e5)return null;e=gn({suppressMilliseconds:!1,suppressSeconds:!1,includePrefix:!1,format:"extended"},e);var n=this.shiftTo("hours","minutes","seconds","milliseconds"),r="basic"===e.format?"hhmm":"hh:mm";e.suppressSeconds&&0===n.seconds&&0===n.milliseconds||(r+="basic"===e.format?"ss":":ss",e.suppressMilliseconds&&0===n.milliseconds||(r+=".SSS"));var i=n.toFormat(r);return e.includePrefix&&(i="T"+i),i},t.toJSON=function(){return this.toISO()},t.toString=function(){return this.toISO()},t.toMillis=function(){return this.as("milliseconds")},t.valueOf=function(){return this.toMillis()},t.plus=function(t){if(!this.isValid)return this;for(var n,r=e.fromDurationLike(t),i={},o=Dn(ho);!(n=o()).done;){var s=n.value;(lr(r.values,s)||lr(this.values,s))&&(i[s]=r.get(s)+this.get(s))}return yo(this,{values:i},!0)},t.minus=function(t){if(!this.isValid)return this;var n=e.fromDurationLike(t);return this.plus(n.negate())},t.mapUnits=function(e){if(!this.isValid)return this;for(var t={},n=0,r=Object.keys(this.values);n<r.length;n++){var i=r[n];t[i]=Tr(e(this.values[i],i))}return yo(this,{values:t},!0)},t.get=function(t){return this[e.normalizeUnit(t)]},t.set=function(t){return this.isValid?yo(this,{values:gn({},this.values,Mr(t,e.normalizeUnit))}):this},t.reconfigure=function(e){var t=void 0===e?{}:e,n=t.locale,r=t.numberingSystem,i=t.conversionAccuracy,o={loc:this.loc.clone({locale:n,numberingSystem:r})};return i&&(o.conversionAccuracy=i),yo(this,o)},t.as=function(e){return this.isValid?this.shiftTo(e).get(e):NaN},t.normalize=function(){if(!this.isValid)return this;var e=this.toObject();return function(e,t){mo.reduce((function(n,r){return ir(t[r])?n:(n&&vo(e,t,n,t,r),r)}),null)}(this.matrix,e),yo(this,{values:e},!0)},t.shiftTo=function(){for(var t=arguments.length,n=new Array(t),r=0;r<t;r++)n[r]=arguments[r];if(!this.isValid)return this;if(0===n.length)return this;n=n.map((function(t){return e.normalizeUnit(t)}));for(var i,o,s={},u={},a=this.toObject(),l=Dn(ho);!(o=l()).done;){var c=o.value;if(n.indexOf(c)>=0){i=c;var f=0;for(var d in u)f+=this.matrix[d][c]*u[d],u[d]=0;or(a[c])&&(f+=a[c]);var h=Math.trunc(f);for(var m in s[c]=h,u[c]=(1e3*f-1e3*h)/1e3,a)ho.indexOf(m)>ho.indexOf(c)&&vo(this.matrix,a,m,s,c)}else or(a[c])&&(u[c]=a[c])}for(var y in u)0!==u[y]&&(s[i]+=y===i?u[y]:u[y]/this.matrix[i][y]);return yo(this,{values:s},!0).normalize()},t.negate=function(){if(!this.isValid)return this;for(var e={},t=0,n=Object.keys(this.values);t<n.length;t++){var r=n[t];e[r]=0===this.values[r]?0:-this.values[r]}return yo(this,{values:e},!0)},t.equals=function(e){if(!this.isValid||!e.isValid)return!1;if(!this.loc.equals(e.loc))return!1;for(var t,n=Dn(ho);!(t=n()).done;){var r=t.value;if(i=this.values[r],o=e.values[r],!(void 0===i||0===i?void 0===o||0===o:i===o))return!1}var i,o;return!0},pn(e,[{key:"locale",get:function(){return this.isValid?this.loc.locale:null}},{key:"numberingSystem",get:function(){return this.isValid?this.loc.numberingSystem:null}},{key:"years",get:function(){return this.isValid?this.values.years||0:NaN}},{key:"quarters",get:function(){return this.isValid?this.values.quarters||0:NaN}},{key:"months",get:function(){return this.isValid?this.values.months||0:NaN}},{key:"weeks",get:function(){return this.isValid?this.values.weeks||0:NaN}},{key:"days",get:function(){return this.isValid?this.values.days||0:NaN}},{key:"hours",get:function(){return this.isValid?this.values.hours||0:NaN}},{key:"minutes",get:function(){return this.isValid?this.values.minutes||0:NaN}},{key:"seconds",get:function(){return this.isValid?this.values.seconds||0:NaN}},{key:"milliseconds",get:function(){return this.isValid?this.values.milliseconds||0:NaN}},{key:"isValid",get:function(){return null===this.invalid}},{key:"invalidReason",get:function(){return this.invalid?this.invalid.reason:null}},{key:"invalidExplanation",get:function(){return this.invalid?this.invalid.explanation:null}}]),e}();var go=function(){function e(e){this.s=e.start,this.e=e.end,this.invalid=e.invalid||null,this.isLuxonInterval=!0}e.invalid=function(t,n){if(void 0===n&&(n=null),!t)throw new Fn("need to specify a reason the Interval is invalid");var r=t instanceof Hr?t:new Hr(t,n);if(li.throwOnInvalid)throw new _n(r);return new e({invalid:r})},e.fromDateTimes=function(t,n){var r=gs(t),i=gs(n),o=function(e,t){return e&&e.isValid?t&&t.isValid?t<e?go.invalid("end before start","The end of an interval must be after its start, but you had start="+e.toISO()+" and end="+t.toISO()):null:go.invalid("missing or invalid end"):go.invalid("missing or invalid start")}(r,i);return null==o?new e({start:r,end:i}):o},e.after=function(t,n){var r=po.fromDurationLike(n),i=gs(t);return e.fromDateTimes(i,i.plus(r))},e.before=function(t,n){var r=po.fromDurationLike(n),i=gs(t);return e.fromDateTimes(i.minus(r),i)},e.fromISO=function(t,n){var r=(t||"").split("/",2),i=r[0],o=r[1];if(i&&o){var s,u,a,l;try{u=(s=ps.fromISO(i,n)).isValid}catch(e){u=!1}try{l=(a=ps.fromISO(o,n)).isValid}catch(e){l=!1}if(u&&l)return e.fromDateTimes(s,a);if(u){var c=po.fromISO(o,n);if(c.isValid)return e.after(s,c)}else if(l){var f=po.fromISO(i,n);if(f.isValid)return e.before(a,f)}}return e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.isInterval=function(e){return e&&e.isLuxonInterval||!1};var t=e.prototype;return t.length=function(e){return void 0===e&&(e="milliseconds"),this.isValid?this.toDuration.apply(this,[e]).get(e):NaN},t.count=function(e){if(void 0===e&&(e="milliseconds"),!this.isValid)return NaN;var t=this.start.startOf(e),n=this.end.startOf(e);return Math.floor(n.diff(t,e).get(e))+1},t.hasSame=function(e){return!!this.isValid&&(this.isEmpty()||this.e.minus(1).hasSame(this.s,e))},t.isEmpty=function(){return this.s.valueOf()===this.e.valueOf()},t.isAfter=function(e){return!!this.isValid&&this.s>e},t.isBefore=function(e){return!!this.isValid&&this.e<=e},t.contains=function(e){return!!this.isValid&&(this.s<=e&&this.e>e)},t.set=function(t){var n=void 0===t?{}:t,r=n.start,i=n.end;return this.isValid?e.fromDateTimes(r||this.s,i||this.e):this},t.splitAt=function(){var t=this;if(!this.isValid)return[];for(var n=arguments.length,r=new Array(n),i=0;i<n;i++)r[i]=arguments[i];for(var o=r.map(gs).filter((function(e){return t.contains(e)})).sort(),s=[],u=this.s,a=0;u<this.e;){var l=o[a]||this.e,c=+l>+this.e?this.e:l;s.push(e.fromDateTimes(u,c)),u=c,a+=1}return s},t.splitBy=function(t){var n=po.fromDurationLike(t);if(!this.isValid||!n.isValid||0===n.as("milliseconds"))return[];for(var r,i=this.s,o=1,s=[];i<this.e;){var u=this.start.plus(n.mapUnits((function(e){return e*o})));r=+u>+this.e?this.e:u,s.push(e.fromDateTimes(i,r)),i=r,o+=1}return s},t.divideEqually=function(e){return this.isValid?this.splitBy(this.length()/e).slice(0,e):[]},t.overlaps=function(e){return this.e>e.s&&this.s<e.e},t.abutsStart=function(e){return!!this.isValid&&+this.e==+e.s},t.abutsEnd=function(e){return!!this.isValid&&+e.e==+this.s},t.engulfs=function(e){return!!this.isValid&&(this.s<=e.s&&this.e>=e.e)},t.equals=function(e){return!(!this.isValid||!e.isValid)&&(this.s.equals(e.s)&&this.e.equals(e.e))},t.intersection=function(t){if(!this.isValid)return this;var n=this.s>t.s?this.s:t.s,r=this.e<t.e?this.e:t.e;return n>=r?null:e.fromDateTimes(n,r)},t.union=function(t){if(!this.isValid)return this;var n=this.s<t.s?this.s:t.s,r=this.e>t.e?this.e:t.e;return e.fromDateTimes(n,r)},e.merge=function(e){var t=e.sort((function(e,t){return e.s-t.s})).reduce((function(e,t){var n=e[0],r=e[1];return r?r.overlaps(t)||r.abutsStart(t)?[n,r.union(t)]:[n.concat([r]),t]:[n,t]}),[[],null]),n=t[0],r=t[1];return r&&n.push(r),n},e.xor=function(t){for(var n,r,i=null,o=0,s=[],u=t.map((function(e){return[{time:e.s,type:"s"},{time:e.e,type:"e"}]})),a=Dn((n=Array.prototype).concat.apply(n,u).sort((function(e,t){return e.time-t.time})));!(r=a()).done;){var l=r.value;1===(o+="s"===l.type?1:-1)?i=l.time:(i&&+i!=+l.time&&s.push(e.fromDateTimes(i,l.time)),i=null)}return e.merge(s)},t.difference=function(){for(var t=this,n=arguments.length,r=new Array(n),i=0;i<n;i++)r[i]=arguments[i];return e.xor([this].concat(r)).map((function(e){return t.intersection(e)})).filter((function(e){return e&&!e.isEmpty()}))},t.toString=function(){return this.isValid?"["+this.s.toISO()+" – "+this.e.toISO()+")":"Invalid Interval"},t.toISO=function(e){return this.isValid?this.s.toISO(e)+"/"+this.e.toISO(e):"Invalid Interval"},t.toISODate=function(){return this.isValid?this.s.toISODate()+"/"+this.e.toISODate():"Invalid Interval"},t.toISOTime=function(e){return this.isValid?this.s.toISOTime(e)+"/"+this.e.toISOTime(e):"Invalid Interval"},t.toFormat=function(e,t){var n=(void 0===t?{}:t).separator,r=void 0===n?" – ":n;return this.isValid?""+this.s.toFormat(e)+r+this.e.toFormat(e):"Invalid Interval"},t.toDuration=function(e,t){return this.isValid?this.e.diff(this.s,e,t):po.invalid(this.invalidReason)},t.mapEndpoints=function(t){return e.fromDateTimes(t(this.s),t(this.e))},pn(e,[{key:"start",get:function(){return this.isValid?this.s:null}},{key:"end",get:function(){return this.isValid?this.e:null}},{key:"isValid",get:function(){return null===this.invalidReason}},{key:"invalidReason",get:function(){return this.invalid?this.invalid.reason:null}},{key:"invalidExplanation",get:function(){return this.invalid?this.invalid.explanation:null}}]),e}(),wo=function(){function e(){}return e.hasDST=function(e){void 0===e&&(e=li.defaultZone);var t=ps.now().setZone(e).set({month:12});return!e.isUniversal&&t.offset!==t.set({month:6}).offset},e.isValidIANAZone=function(e){return Kr.isValidZone(e)},e.normalizeZone=function(e){return ni(e,li.defaultZone)},e.months=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj,a=void 0===u?null:u,l=n.outputCalendar,c=void 0===l?"gregory":l;return(a||xi.create(i,s,c)).months(e)},e.monthsFormat=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj,a=void 0===u?null:u,l=n.outputCalendar,c=void 0===l?"gregory":l;return(a||xi.create(i,s,c)).months(e,!0)},e.weekdays=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj;return((void 0===u?null:u)||xi.create(i,s,null)).weekdays(e)},e.weekdaysFormat=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj;return((void 0===u?null:u)||xi.create(i,s,null)).weekdays(e,!0)},e.meridiems=function(e){var t=(void 0===e?{}:e).locale,n=void 0===t?null:t;return xi.create(n).meridiems()},e.eras=function(e,t){void 0===e&&(e="short");var n=(void 0===t?{}:t).locale,r=void 0===n?null:n;return xi.create(r,null,"gregory").eras(e)},e.features=function(){return{relative:ur()}},e}();function ko(e,t){var n=function(e){return e.toUTC(0,{keepLocalTime:!0}).startOf("day").valueOf()},r=n(t)-n(e);return Math.floor(po.fromMillis(r).as("days"))}function bo(e,t,n,r){var i=function(e,t,n){for(var r,i,o={},s=0,u=[["years",function(e,t){return t.year-e.year}],["quarters",function(e,t){return t.quarter-e.quarter}],["months",function(e,t){return t.month-e.month+12*(t.year-e.year)}],["weeks",function(e,t){var n=ko(e,t);return(n-n%7)/7}],["days",ko]];s<u.length;s++){var a=u[s],l=a[0],c=a[1];if(n.indexOf(l)>=0){var f;r=l;var d,h=c(e,t);(i=e.plus(((f={})[l]=h,f)))>t?(e=e.plus(((d={})[l]=h-1,d)),h-=1):e=i,o[l]=h}}return[e,o,i,r]}(e,t,n),o=i[0],s=i[1],u=i[2],a=i[3],l=t-o,c=n.filter((function(e){return["hours","minutes","seconds","milliseconds"].indexOf(e)>=0}));if(0===c.length){var f;if(u<t)u=o.plus(((f={})[a]=1,f));u!==o&&(s[a]=(s[a]||0)+l/(u-o))}var d,h=po.fromObject(s,r);return c.length>0?(d=po.fromMillis(l,r)).shiftTo.apply(d,c).plus(h):h}var xo={arab:"[٠-٩]",arabext:"[۰-۹]",bali:"[᭐-᭙]",beng:"[০-৯]",deva:"[०-९]",fullwide:"[０-９]",gujr:"[૦-૯]",hanidec:"[〇|一|二|三|四|五|六|七|八|九]",khmr:"[០-៩]",knda:"[೦-೯]",laoo:"[໐-໙]",limb:"[᥆-᥏]",mlym:"[൦-൯]",mong:"[᠐-᠙]",mymr:"[၀-၉]",orya:"[୦-୯]",tamldec:"[௦-௯]",telu:"[౦-౯]",thai:"[๐-๙]",tibt:"[༠-༩]",latn:"\\d"},So={arab:[1632,1641],arabext:[1776,1785],bali:[6992,7001],beng:[2534,2543],deva:[2406,2415],fullwide:[65296,65303],gujr:[2790,2799],khmr:[6112,6121],knda:[3302,3311],laoo:[3792,3801],limb:[6470,6479],mlym:[3430,3439],mong:[6160,6169],mymr:[4160,4169],orya:[2918,2927],tamldec:[3046,3055],telu:[3174,3183],thai:[3664,3673],tibt:[3872,3881]},To=xo.hanidec.replace(/[\[|\]]/g,"").split("");function Mo(e,t){var n=e.numberingSystem;return void 0===t&&(t=""),new RegExp(""+xo[n||"latn"]+t)}function Oo(e,t){return void 0===t&&(t=function(e){return e}),{regex:e,deser:function(e){var n=e[0];return t(function(e){var t=parseInt(e,10);if(isNaN(t)){t="";for(var n=0;n<e.length;n++){var r=e.charCodeAt(n);if(-1!==e[n].search(xo.hanidec))t+=To.indexOf(e[n]);else for(var i in So){var o=So[i],s=o[0],u=o[1];r>=s&&r<=u&&(t+=r-s)}}return parseInt(t,10)}return t}(n))}}}var Do="[ "+String.fromCharCode(160)+"]",No=new RegExp(Do,"g");function Eo(e){return e.replace(/\./g,"\\.?").replace(No,Do)}function _o(e){return e.replace(/\./g,"").replace(No," ").toLowerCase()}function Io(e,t){return null===e?null:{regex:RegExp(e.map(Eo).join("|")),deser:function(n){var r=n[0];return e.findIndex((function(e){return _o(r)===_o(e)}))+t}}}function Vo(e,t){return{regex:e,deser:function(e){return Sr(e[1],e[2])},groups:t}}function Co(e){return{regex:e,deser:function(e){return e[0]}}}var Fo={year:{"2-digit":"yy",numeric:"yyyyy"},month:{numeric:"M","2-digit":"MM",short:"MMM",long:"MMMM"},day:{numeric:"d","2-digit":"dd"},weekday:{short:"EEE",long:"EEEE"},dayperiod:"a",dayPeriod:"a",hour:{numeric:"h","2-digit":"hh"},minute:{numeric:"m","2-digit":"mm"},second:{numeric:"s","2-digit":"ss"}};var zo=null;function Ao(e,t){if(e.literal)return e;var n=Ur.macroTokenToFormatOpts(e.val);if(!n)return e;var r=Ur.create(t,n).formatDateTimeParts((zo||(zo=ps.fromMillis(1555555555555)),zo)).map((function(e){return function(e,t,n){var r=e.type,i=e.value;if("literal"===r)return{literal:!0,val:i};var o=n[r],s=Fo[r];return"object"==typeof s&&(s=s[o]),s?{literal:!1,val:s}:void 0}(e,0,n)}));return r.includes(void 0)?e:r}function Lo(e,t,n){var r=function(e,t){var n;return(n=Array.prototype).concat.apply(n,e.map((function(e){return Ao(e,t)})))}(Ur.parseFormat(n),e),i=r.map((function(t){return n=t,i=Mo(r=e),o=Mo(r,"{2}"),s=Mo(r,"{3}"),u=Mo(r,"{4}"),a=Mo(r,"{6}"),l=Mo(r,"{1,2}"),c=Mo(r,"{1,3}"),f=Mo(r,"{1,6}"),d=Mo(r,"{1,9}"),h=Mo(r,"{2,4}"),m=Mo(r,"{4,6}"),y=function(e){return{regex:RegExp((t=e.val,t.replace(/[\-\[\]{}()*+?.,\\\^$|#\s]/g,"\\$&"))),deser:function(e){return e[0]},literal:!0};var t},v=function(e){if(n.literal)return y(e);switch(e.val){case"G":return Io(r.eras("short",!1),0);case"GG":return Io(r.eras("long",!1),0);case"y":return Oo(f);case"yy":case"kk":return Oo(h,br);case"yyyy":case"kkkk":return Oo(u);case"yyyyy":return Oo(m);case"yyyyyy":return Oo(a);case"M":case"L":case"d":case"H":case"h":case"m":case"q":case"s":case"W":return Oo(l);case"MM":case"LL":case"dd":case"HH":case"hh":case"mm":case"qq":case"ss":case"WW":return Oo(o);case"MMM":return Io(r.months("short",!0,!1),1);case"MMMM":return Io(r.months("long",!0,!1),1);case"LLL":return Io(r.months("short",!1,!1),1);case"LLLL":return Io(r.months("long",!1,!1),1);case"o":case"S":return Oo(c);case"ooo":case"SSS":return Oo(s);case"u":return Co(d);case"uu":return Co(l);case"uuu":case"E":case"c":return Oo(i);case"a":return Io(r.meridiems(),0);case"EEE":return Io(r.weekdays("short",!1,!1),1);case"EEEE":return Io(r.weekdays("long",!1,!1),1);case"ccc":return Io(r.weekdays("short",!0,!1),1);case"cccc":return Io(r.weekdays("long",!0,!1),1);case"Z":case"ZZ":return Vo(new 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e=JSON.parse(this.responseText).intradayPricing,t=0,n=yn.DateTime.now();e.length>0&&(t=parseFloat(e[e.length-1].price).toFixed(2),n=yn.DateTime.fromISO(e[e.length-1].time));document.getElementById("md-current-price").innerHTML="$"+t;document.getElementById("md-current-time").innerHTML=n.toLocaleString(yn.DateTime.DATETIME_FULL);const r=[],i=[];e.forEach((e=>{const{price:t,time:n}=e,o=yn.DateTime.fromISO(n),s=parseFloat(t).toFixed(2);r.push(o.toUnixInteger()),i.push(s)}));const o=document.getElementById("md-intraday-chart"),s=new mn({width:300,height:120,class:"spark",pxAlign:!1,cursor:{show:!1},select:{show:!1},legend:{show:!1},scales:{x:{time:!1}},axes:[{show:!1},{show:!1}],series:[{},{stroke:"#ec5b2e",fill:"#ffb39c"}]},[r,i]).ctx.canvas;o.parentNode.append(s)}},ws.open("GET","https://medtech100.com/md100/json/pricing",!0),ws.send(); //# sourceMappingURL=index.80f28a61.js.map </script> </head> <body> <div id="md-tech-ad"> <table class="md-table" align="center" cellpadding="0" cellspacing="0" width="100%"> <tr> <td width="100%"> <div class="md-align"> <img id="md-logo" class="md-margin" src="https://images.designworldonline.com/newsletters/images/ee034d8d8274c1ee5e8111f11cf1be49.png" alt="Medtech 100 logo"> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align"> <div class="margin-text"> <span style="font-weight:600;color:#e06636!important;font-size:16px!important;line-height:14px!important"> Market Summary > Current Price </span> </div> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align" id="md-content-container"> <div id="md-current-price"></div> <div id="md-current-time"></div> <div id="md-chart-container"> <div id="md-intraday-chart"></div> </div> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align"> <div class="md-margin-text"> <span style="font-size:13px;line-height:15px!important"> The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing. </span> </div> </div> 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