Proteome Profiler Human Protease Array Kit ARY021B: R&D Systems

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class="ds_title_table"> <h1 class="ds_title">Proteome Profiler Human Protease Array Kit </h1> <div class="dsSprite_rnd ds_brand_logo ds_rnd_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: ARY021B</span> <br/> <span class="citations"> <a href="#product-citations" id="citation_count" class="jump_to" data-tab="3" data-tabname="product-citations"> 28 Citations </a> </span> <span class="reviews review_stars_5"> <a href="#product-reviews" id="product_reviews" class="jump_to" data-tab="6" data-tabname="product-reviews"> 1 Review </a> </span> <a href="/reviews/ARY021B" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div> <div class="product_info">Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies</div>  <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/proteome-profiler-human-protease-array-kit_ary021b" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block">     <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th class="ds_size_price_column">Size / Price</th> <th class="ds_quantity_column">Qty</th> </tr> </thead> <tbody> <tr class="et_atc_product" data-sku="ARY021B"> <td class="dat_catalog_column">ARY021B</td> <td class="et_atc_results" colspan="2"></td> <td class="ds_quantity ds_quantity_column"><div class="form-item form-item-catnum-ary021b form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-ary021b" name="catnum-ARY021B" value="" size="5" maxlength="3" /></div></td> </tr> </tbody> </table> <div class="ds_atc_pre_buttons"></div> <div class="ds_atc_buttons"> <a href="/quote/instruments/ella-automated-immunoassay-system" class="btn btn-secondary atc_request_quote_simple_plex_assay" style="display:none" rel="nofollow">Request a Quote</a> <a href="/services/bulk-quote-request?catnum=ARY021B&product=Proteome Profiler Human Protease Array Kit" class="btn btn-secondary atc_hidden bulk_btn" style="display:none;" rel="nofollow" title="Competitive discounts on products purchased in bulk quantities">Bulk Orders</a> <button class="btn btn-primary atc_hidden atc_btn form-submit icon-before" style="display:none;" title="Enter quantities above and click to add to cart" type="submit" id="edit-add-to-cart" name="add_to_cart_btn" value="Add to Cart"><span class="icon glyphicon glyphicon-plus" aria-hidden="true"></span> Add to Cart</button> </div> <div class="ds_atc_post_buttons"></div> </div> <input type="hidden" name="form_build_id" 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No. ARY021B - Proteome Profiler Human Protease Array Kit" href="https://resources.rndsystems.com/categoryimages/rndsystems_proteome-profiler-antibody-array-kits.jpg"> <img fetchpriority="high" src="https://resources.rndsystems.com/categoryimages/rndsystems_proteome-profiler-antibody-array-kits.jpg" class="img-fluid" alt="R&D Systems Proteome Profiler Antibody Array Kits" title="R&D Systems Proteome Profiler Antibody Array Kits"> </a> <div class="search_image_other_count"> <span class="search_more_images">1 Image</span> </div> </div> </div> <div id="extra_images overview-images" class="hidden"> </div> </div> <div class="product_info_wrapper"> </div> <div id="view-more-target" class="datasheet_section_element"> View <a href="/target/protease-array-kits">All Products for Protease Array Kits</a> </div> </div>  <div class="tabbed_content" id="rnd_atlantabio">  <div id="ds_tabs" class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="product-details" id="dsTabs_product-details"> <span>Product Details</span> </div> <div class="tab tab_3" data-tab="3" data-tabname="product-citations" id="dsTabs_product-citations"> <span>Citations (28)</span> </div> <div class="tab tab_4" data-tab="4" data-tabname="faqs" id="dsTabs_faqs"> <span>FAQs</span> </div> <div class="tab tab_5" data-tab="5" data-tabname="supplemental-products" id="dsTabs_supplemental-products"> <span>Supplemental Products</span> </div> <div class="tab tab_6" data-tab="6" data-tabname="product-reviews" id="dsTabs_product-reviews"> <span> Reviews (1) </span> </div> </div>  <div class="tab_content tab_1 tab_open" data-tab="1" data-tabname="product-details" id="product-details"> <div class="datasheet_section_element"> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_summary" id="product-anchor-ds_summary">Summary</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_datasheets" id="product-anchor-ds_datasheets">Product Datasheets</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_data_examples" id="product-anchor-ds_data_examples">Data Images</a> </div> <div id="ds_summary" class="datasheet_section"> <h2>Proteome Profiler Human Protease Array Kit Summary</h2> <div id="ds_product_details" class="datasheet_section"> <div class="ds_lightBlueBar">Kit Summary</div> <h2>To simultaneously detect the relative changes of 35 proteases in a single sample. No specialized equipment is necessary</h2> <p> </p> <a href="https://www.rndsystems.com/resources/technical/troubleshooting-guide-human-proteome-profiler-array-kits"><strong>Troubleshooting Guide</strong></a> <div class="clear"> </div> <h3>General Assay Principle</h3> <p>Carefully selected capture antibodies have been spotted in duplicate on nitrocellulose membranes. Cell culture supernates, cell lysates, serum, plasma, urine, saliva, or tissue lysate samples are diluted and mixed with a cocktail of biotinylated detection antibodies. The sample/antibody mixture is then incubated with the array. Any protein/detection antibody complex present is bound by its cognate immobilized capture antibody on the membrane. Streptavidin-Horseradish Peroxidase and chemiluminescent detection reagents are added, and a signal is produced in proportion to the amount of protein bound. Chemiluminescence is detected in the same manner as a Western blot.</p> <p> </p> <div class="ds_lightBlueBar">Kit Contents</div> <ul> <li>4 Array Membranes</li> <li>4-Well Multi-dish</li> <li>Array Buffers</li> <li>Wash Buffer</li> <li>Detection Antibody Cocktail</li> <li>Streptavidin-HRP</li> <li>Chemiluminescent Detection Reagents</li> <li>Transparency Overlay Template</li> <li>Detailed Protocol</li> </ul> <p>For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the <a href="//resources.rndsystems.com/pdfs/datasheets/ary021b.pdf">Product Datasheet</a>.</p> <h3>Stability and Storage</h3> <p>Store the unopened product at 2<sup>°</sup> C to 8<sup>°</sup> C. Do not use past expiration date.</p> <div class="clear"> </div> <table align="center" cellpadding="3" cellspacing="0" class="border" width="100%"> <tbody> <tr> <td class="blue_high" colspan="3"> <p>Simultaneously detect the relative levels of these proteases in a single sample.</p> </td> </tr> <tr> <td>ADAM8</td> <td>Cathepsin X/Z/P</td> <td>MMP-7</td> </tr> <tr> <td class="lt_gray">ADAM9</td> <td class="lt_gray">DPPIV/CD26</td> <td class="lt_gray">MMP-8</td> </tr> <tr> <td>ADAMTS1</td> <td>Kallikrein 3/PSA</td> <td>MMP-9</td> </tr> <tr> <td class="lt_gray">ADAMTS13</td> <td class="lt_gray">Kallikrein 5</td> <td class="lt_gray">MMP-10</td> </tr> <tr> <td>Cathepsin A</td> <td>Kallikrein 6</td> <td>MMP-12</td> </tr> <tr> <td class="lt_gray">Cathepsin B</td> <td class="lt_gray">Kallikrein 7</td> <td class="lt_gray">MMP-13</td> </tr> <tr> <td>Cathepsin C/DPPI</td> <td>Kallikrein 10</td> <td>Neprilysin/CD10</td> </tr> <tr> <td class="lt_gray">Cathepsin D</td> <td class="lt_gray">Kallikrein 11</td> <td class="lt_gray">Presenilin-1</td> </tr> <tr> <td>Cathepsin E</td> <td>Kallikrein 13</td> <td>Proprotein Convertase 9</td> </tr> <tr> <td class="lt_gray">Cathepsin L</td> <td class="lt_gray">MMP-1</td> <td class="lt_gray">Proteinase 3</td> </tr> <tr> <td>Cathepsin S</td> <td>MMP-2</td> <td>uPA/Urokinase</td> </tr> <tr> <td class="lt_gray">Cathepsin V</td> <td class="lt_gray">MMP-3</td> <td class="lt_gray"> </td> </tr> </tbody> </table> <a name="assays"></a> <h4>Assays for Analytes represented in the Human Protease Array Kit</h4> <table align="center" cellpadding="3" cellspacing="0" class="border" width="100%"> <tbody> <tr> <td class="blue_high" valign="bottom">Analyte</td> <td class="blue_high" valign="bottom">Quantikine<sup>®</sup> ELISA Kits</td> <td class="blue_high" valign="bottom">DuoSet<sup>®</sup> ELISA Development Systems</td> </tr> <tr> <td class="lt_gray">ADAM8</td> <td class="lt_gray"> </td> <td class="lt_gray"><a href="/products/human-adam8-duoset-elisa_dy1031">DY1031</a></td> </tr> <tr> <td>ADAM9</td> <td> </td> <td><a href="products/human-adam9-duoset-elisa_dy939">DY939</a></td> </tr> <tr> <td class="lt_gray">ADAMTS1</td> <td class="lt_gray"> </td> <td class="lt_gray"><a href="/products/human-adamts1-duoset-elisa_dy2197">DY2197</a></td> </tr> <tr> <td>ADAMTS13</td> <td><a href="/products/human-adamts13-quantikine-elisa-kit_dadt130">DADT130</a></td> <td> </td> </tr> <tr> <td class="lt_gray">Cathepsin A</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>Cathepsin B</td> <td><a href="/products/DCATB0">DCATB0</a></td> <td><a href="/products/human-pro-cathepsin-b-duoset-elisa_dy953">DY953</a>, <a href="/products/human-total-cathepsin-b-duoset-elisa_dy2176">DY2176</a></td> </tr> <tr> <td class="lt_gray">Cathepsin C/DPPI</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>Cathepsin D</td> <td> </td> <td> </td> </tr> <tr> <td class="lt_gray">Cathepsin E</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>Cathepsin L</td> <td> </td> <td><a href="/products/human-cathepsin-l-duoset-elisa_dy952">DY952</a></td> </tr> <tr> <td class="lt_gray">Cathepsin S</td> <td class="lt_gray"> </td> <td class="lt_gray"><a href="/products/human-total-cathepsin-s-duoset-elisa_dy1183">DY1183,</a> <a href="/products/human-pro-cathepsin-s-duoset-elisa_dy2227">DY2227</a></td> </tr> <tr> <td>Cathepsin V</td> <td> </td> <td><a href="/products/human-cathepsin-v-duoset-elisa_dy1080">DY1080</a></td> </tr> <tr> <td class="lt_gray">Cathepsin X/Z/P</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>DPPIV/CD26</td> <td> </td> <td><a href="/products/human-dppiv-cd26-duoset-elisa_dy1180">DY1180</a></td> </tr> <tr> <td class="lt_gray">Kallikrein 3/PSA</td> <td class="lt_gray"><a href="/products/human-kallikrein-3-psa-quantikine-elisa-kit_dkk300">DKK300</a></td> <td class="lt_gray"><a href="/products/human-kallikrein-3-psa-duoset-elisa_dy1344">DY1344</a></td> </tr> <tr> <td>Kallikrein 5</td> <td><a href="/products/human-kallikrein-5-quantikine-elisa-kit_dkk500">DKK500</a></td> <td> </td> </tr> <tr> <td class="lt_gray">Kallikrein 6</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>Kallikrein 7</td> <td> </td> <td> </td> </tr> <tr> <td class="lt_gray">Kallikrein 10</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>Kallikrein 11</td> <td> </td> <td> </td> </tr> <tr> <td class="lt_gray">Kallikrein 13</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>MMP-1</td> <td><a href="/products/human-pro-mmp-1-quantikine-elisa-kit_dmp100">DMP100</a></td> <td> </td> </tr> <tr> <td class="lt_gray">MMP-2</td> <td class="lt_gray"><a href="/products/total-mmp-2-quantikine-elisa-kit_mmp200">MMP200</a></td> <td class="lt_gray"><a href="/products/human-mmp-2-duoset-elisa_dy902">DY902</a></td> </tr> <tr> <td>MMP-3</td> <td><a href="/products/human-total-mmp-3-quantikine-elisa-kit_dmp300">DMP300</a></td> <td><a href="/products/human-total-mmp-3-duoset-elisa_dy513">DY513</a></td> </tr> <tr> <td class="lt_gray">MMP-7</td> <td class="lt_gray"><a href="/products/human-total-mmp-7-quantikine-elisa-kit_dmp700">DMP700</a></td> <td class="lt_gray"><a href="/products/human-total-mmp-7-duoset-elisa_dy907">DY907</a></td> </tr> <tr> <td>MMP-8</td> <td><a href="/products/human-total-mmp-8-quantikine-elisa-kit_dmp800">DMP800</a></td> <td><a href="/products/human-total-mmp-8-duoset-elisa_dy908">DY908</a></td> </tr> <tr> <td class="lt_gray">MMP-9</td> <td class="lt_gray"><a href="/products/human-mmp-9-quantikine-elisa-kit_dmp900">DMP900</a></td> <td class="lt_gray"><a href="/products/human-mmp-9-duoset-elisa_dy911">DY911</a></td> </tr> <tr> <td>MMP-10</td> <td><a href="/products/human-pro-mmp-10-quantikine-elisa-kit_dm1000">DM1000</a></td> <td><a href="/products/human-total-mmp-10-duoset-elisa_dy910">DY910</a></td> </tr> <tr> <td class="lt_gray">MMP-12</td> <td class="lt_gray"> </td> <td class="lt_gray"> </td> </tr> <tr> <td>MMP-13</td> <td><a href="/products/human-pro-mmp-13-quantikine-elisa-kit_dm1300">DM1300</a></td> <td><a href="/products/human-total-mmp-13-duoset-elisa_dy511">DY511</a>, <a href="/products/human-pro-mmp-13-duoset-elisa_dy913">DY913</a></td> </tr> <tr> <td class="lt_gray">Neprilysin</td> <td class="lt_gray"> </td> <td class="lt_gray"><a href="/products/human-neprilysin-duoset-elisa_dy1182">DY1182</a></td> </tr> <tr> <td>Presenilin-1</td> <td> </td> <td><a href="/products/human-presenilin-1-n-term-duoset-elisa_dy149">DY149</a></td> </tr> <tr> <td class="lt_gray">Proprotein Convertase 9</td> <td class="lt_gray"><a href="/products/human-proprotein-convertase-9-pcsk9-quantikine-elisa-kit_dpc900">DPC900</a></td> <td class="lt_gray"><a href="/products/human-proprotein-convertase-9-pcsk9-duoset-elisa_dy3888">DY3888</a></td> </tr> <tr> <td>Proteinase 3</td> <td> </td> <td><a href="/products/human-proteinase-3-prtn3-duoset-elisa_dy6134-05">DY6134-05</a></td> </tr> <tr> <td class="lt_gray">uPA/Urokinase</td> <td class="lt_gray"><a href="/products/human-u-plasminogen-activator-urokinase-quantikine-elisa_dupa00">DUPA00</a></td> <td class="lt_gray"><a href="/products/human-u-plasminogen-activator-urokinase-duoset-elisa_dy1310">DY1310</a></td> </tr> </tbody> </table> </div> <h3 class="subheader18 mt-1">Specifications</h3> <div class="ds_table summary_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Shipping Conditions</div> <div class="ds_table_cell summary_table_data">The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Storage</div> <div class="ds_table_cell summary_table_data">Store the unopened product at 2 - 8 °C. Do not use past expiration date.</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Species</div> <div class="ds_table_cell summary_table_data">Human</div> </div> </div> </div> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets"> <span class="sds-message hide"> <p class="sds-label">You must select a language.</p> <span class="close_sds_message">x</span> </span> <div class="ds_document"> <a id="cfpdf" href="//resources.rndsystems.com/pdfs/datasheets/ary021b.pdf?v=20241122" class="datasheets-link " target="_blank" rel="noreferrer nofollow">Product Datasheet</a> </div> <div class="ds_document"> <div class="ds_pdfData"><a class="datasheets-link" href="https://www.rndsystems.com/cofas/proteome-profiler-human-protease-array-kit_ary021b">COA</a> </div> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//resources.rndsystems.com/pdfs/msds/ary021b.pdf?v=20241122">SDS</a> </div> </div> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="ARY021B"></div> <div id="ds_related_research_areas" class="datasheet_section"> <h2>Related Research Areas</h2> <ul class="ds_details"> <li> <a href="/research-area/alpha-granule-soluble-molecules">Alpha Granule Soluble Molecules</a> </li> </ul> </div> </div>   <div class="tab_content tab_3" data-tab="3" data-tabname="product-citations" id="citations"> <a id="citations_section"></a> <h2><span class="citations">Citations for Proteome Profiler Human Protease Array Kit</h2> <div id="citation"> <a id="dsTabCitations"></a> <p> R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. </p> <p> <strong><span id="maxcitations">28</span> Citations: Showing <span id="showfrom">1</span> - <span id="showto">10</span> </strong> <br/><strong>Filter your results:</strong> </p> <div class="row"> <div class="col-sm-12"> <div class="citations_filters"> <p style="display:inline;"><b>Filter by:</b></p> <div class="select_wrapper filter_select"> <select id="selSpecies" title="Species"> <option value="All">All Species</option> <option class="citation_filterRadio" value="species" data-filter="Human"> Human </option> <option class="citation_filterRadio" value="species" data-filter="Mouse"> Mouse </option> </select> </div> <input type="hidden" id="selAntibody" value="All"> <div class="select_wrapper filter_select"> <select id="selSampleType" title="Sample Types"> <option value="All">All Sample Types</option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Culture Supernates"> Cell Culture Supernates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Lysates"> Cell Lysates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Conditioned Media"> Conditioned Media </option> <option class="citation_filterRadio" value="sampletype" data-filter="Protein"> Protein </option> <option class="citation_filterRadio" value="sampletype" data-filter="Tissue Homogenates"> Tissue Homogenates </option> </select> </div> </div> </div> </div> <div class="row"> <ol id="citations" class="col-xs-12" data-expandall="false" data-max-citations="28" data-max-show="10"> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/39159189"> Pyrocurzerenone suppresses human oral cancer cell metastasis by inhibiting the expression of ERK1/2 and cathepsin S proteins </a> </span><br/> Authors: Hsieh, MJ;Lin, CC;Ho, HY;Chuang, YC;Lo, YS;Chen, MK;<br/> Journal of cellular and molecular medicine  2024-08-01 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37710409"> Epiberberine suppresses the metastasis of head and neck squamous cell carcinoma cells by regulating the MMP-13 and JNK pathway </a> </span><br/> Authors: Ho, HY;Chen, MK;Lin, CC;Lo, YS;Chuang, YC;Hsieh, MJ;<br/> Journal of cellular and molecular medicine  2023-09-14 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37651233"> Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion </a> </span><br/> Authors: Gutierrez-Ruiz, OL;Johnson, KM;Krueger, EW;Nooren, RE;Cruz-Reyes, N;Heppelmann, CJ;Hogenson, TL;Fernandez-Zapico, ME;McNiven, MA;Razidlo, GL;<br/> Cell reports  2023-08-30 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37205750"> Multiscale stiffness of human emphysematous precision cut lung slices </a> </span><br/> Authors: Kim, JH;Schaible, N;Hall, JK;Bartol�k-Suki, E;Deng, Y;Herrmann, J;Sonnenberg, A;Behrsing, HP;Lutchen, KR;Krishnan, R;Suki, B;<br/> Science advances  2023-05-19 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37055381"> Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells </a> </span><br/> Authors: S Li, DM Pritchard, LG Yu<br/> Cell Death & Disease, 2023-04-13;14(4):268.  2023-04-13 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/36993368"> Overexpressed Malat1 Drives Metastasis through Inflammatory Reprogramming of Lung Adenocarcinoma Microenvironment </a> </span><br/> Authors: E Mart Nez-T, FJ de Miguel, V Li, C Robles-Ote, K Politi, JR Zamudio, N Dimitrova<br/> bioRxiv : the preprint server for biology, 2023-03-23;0(0):.  2023-03-23 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" 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2022-06-10;14(6):.  2022-06-10 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/35176662"> Decidual macrophage derived MMP3 contributes to extracellular matrix breakdown in spiral artery remodeling in early human pregnancy </a> </span><br/> Authors: Y Pan, L Yang, D Chen, H Hou, M Zhang, M Chen, F Ning, Q Lu, M Zhao, L Li, GE Lash<br/> Journal of reproductive immunology, 2022-02-11;150(0):103494.  2022-02-11 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/35011011"> Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds </a> </span><br/> Authors: SW Shin, YS Hwang<br/> Nutrients, 2021-12-28;14(1):.  2021-12-28 <br/> </li> <div id="ds_extra_cits"> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/34439122"> Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma </a> </span><br/> Authors: JB Candido, O Maiques, M Boxberg, V Kast, E Peerani, E Tomás-Bort, W Weichert, A Sananes, N Papo, V Magdolen, V Sanz-Moren, D Loessner<br/> Cancers, 2021-08-05;13(16):.  2021-08-05 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/34080661"> Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial?mesenchymal transition and inhibition of MMP?2 </a> </span><br/> Authors: YC Chuang, MC Hsieh, CC Lin, YS Lo, HY Ho, MJ Hsieh, JT Lin<br/> Oncology reports, 2021-06-03;46(1):.  2021-06-03 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Protein"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/33255937"> Gingival Crevicular Fluid Zinc- and Aspartyl-Binding Protease Profile of Individuals with Moderate/Severe Atopic Dermatitis </a> </span><br/> Authors: F Valenzuela, J Fernández, M Aroca, C Jiménez, D Albers, M Hernández, A Fernández<br/> Biomolecules, 2020-11-26;10(12):.  2020-11-26 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Conditioned Media"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/31611973"> Cancer-associated fibroblast stimulates cancer cell invasion 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Effects of Dryopteris crassirhizoma Extract by Disturbing Actin Polymerization </a> </span><br/> Authors: J Lee, YH Nho, SK Yun, YS Hwang<br/> Integr Cancer Ther, 2019-01-01;18(0):1534735419851.  2019-01-01 <br/> </li> <li class="top-lined" data-species="Mouse" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/30906859"> Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis </a> </span><br/> Authors: MR Blatchley, F Hall, S Wang, HC Pruitt, S Gerecht<br/> Sci Adv, 2019;5(3):eaau7518.  2019 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/30123360"> Stromal mesenchymal stem cells facilitate pancreatic cancer progression by regulating specific secretory molecules through mutual cellular interaction </a> </span><br/> Authors: K Saito, M Sakaguchi, S Maruyama, H Iioka, EW Putranto, IW Sumardika, N Tomonobu, T Kawasaki, K Homma, E Kondo<br/> J Cancer, 2018-07-30;9(16):2916-2929.  2018-07-30 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/29933129"> Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3 </a> </span><br/> Authors: SA Greenall, J Donoghue, TG Johns, TE Adams<br/> Transl Oncol, 2018-06-22;11(4):971-978.  2018-06-22 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/29879188"> Intranasal delivery of VEGF enhances compensatory lung growth in mice </a> </span><br/> Authors: DT Dao, JT Vuong, L Anez-Busti, A Pan, PD Mitchell, GL Fell, MA Baker, DR Bielenberg, M Puder<br/> PLoS ONE, 2018-06-07;13(6):e0198700.  2018-06-07 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28737509"> Astrocytic tight junctions control inflammatory CNS lesion pathogenesis </a> </span><br/> Authors: S Horng, A Therattil, S Moyon, A Gordon, K Kim, AT Argaw, Y Hara, JN Mariani, S Sawai, P Flodby, ED Crandall, Z Borok, MV Sofroniew, C Chapouly, GR John<br/> J. Clin. Invest., 2017-07-24;0(0):.  2017-07-24 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28494859"> HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype </a> </span><br/> Authors: NPY Chung, X Ou, KMF Khan, J Salit, RJ Kaner, RG Crystal<br/> Cell Rep, 2017-05-09;19(6):1091-1100.  2017-05-09 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28327651"> Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways </a> </span><br/> Authors: MJ Hsieh, CW Lin, MK Chen, SY Chien, YS Lo, YC Chuang, YT Hsi, CC Lin, JC Chen, SF Yang<br/> Sci Rep, 2017-03-22;7(0):45039.  2017-03-22 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28011764"> Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin </a> </span><br/> Proc. Natl. Acad. Sci. U.S.A, 2016-12-23;0(0):.  2016-12-23 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/26718772"> Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells. </a> </span><br/> Authors: Mohammed F, Khajah M, Yang M, Brackenbury W, Luqmani Y<br/> Int J Oncol, 2015-11-09;48(1):73-83.  2015-11-09 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/26268658"> Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis. </a> </span><br/> Authors: Andrade B, Pavan Kumar N, Amaral E, Riteau N, Mayer-Barber K, Tosh K, Maier N, Conceicao E, Kubler A, Sridhar R, Banurekha V, Jawahar M, Barbosa T, Manganiello V, Moss J, Fontana J, Marciano B, Sampaio E, Olivier K, Holland S, Jackson S, Moayeri M, Leppla S, Sereti I, Barber D, Nutman T, Babu S, Sher A<br/> J Immunol, 2015-08-12;195(6):2763-73.  2015-08-12 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/25454284"> Decidual GM-CSF is a critical common intermediate necessary for thrombin and TNF induced in-vitro fetal membrane weakening. </a> </span><br/> Authors: Kumar D, Moore R, Nash A, Springel E, Mercer B, Philipson E, Mansour J, Moore J<br/> Placenta, 2014-10-12;35(12):1049-56.  2014-10-12 <br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/25217834"> Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells. </a> </span><br/> Authors: Rohrborn D, Eckel J, Sell H<br/> FEBS Lett, 2014-09-12;588(21):3870-7.  2014-09-12 <br/> </li> </div> </ol> </div> <div class="clearfix"><button class="btn btn-quinary ds_extra_cits pull-right toggle_cits_down" id="toggle_cits"></button></div> </div> </div>  <div class="tab_content tab_4" data-tab="4" data-tabname="product-faqs" id="product-faqs"> <h2>FAQs</h2> <div class="row"> <div class="col-xs-12"> <ol id="faq_list"> <li> <span class="faq_question"><p>Could you tell us whether this MMP-9 antibody can detect TIMP and MMP-9 complex?</p></span> <ul class="faq_answer"> <li><p>We haven't performed a large amount of specificity testing per each spot in the arrays because these are qualitative screening tools. However, we would recommend treating the MMP-9 spot as a "Total MMP-9" detecting both free MMP-9 and MMP-9 in complex. If the MMP-9 spot turns out to be of high interest for the customer's study, they will want to examine this target in more detail with quantitative tools such as ELISA or Luminex.</p></li> </ul> </li> </ol> <a class="btn btn-quinary view_all_faqs_btn" href="/resources/faqs/proteome-profiler-antibody-arrays"> View all Proteome Profiler Antibody Array FAQs </a> </div> </div> </div>  <div class="tab_content tab_5" data-tab="5" data-tabname="product-supplemental" id="supplemental-products"> <div id="supplemental-products-tab-content-placeholder" class="tab-content-placeholder" data-id="supplemental-products" data-catalog_number="ary021b" data-language="en"> <div class="et_spinner_small"></div> Loading... </div> </div>  <div class="tab_content tab_6" data-tab="6" data-tabname="product-reviews" id="reviews"> <h3>Reviews for Proteome Profiler Human Protease Array Kit</h3> <div class="row"> <div class="col-xs-12"> <div class="datasheet_section"> <div class="row"> <div class="col-md-6"> <p> 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