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js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" data-click-track="profile-user-info-unfollow-button" data-unfollow-user-id="35639169"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">done</span>Following</button></div></div><div class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Followers</p><p class="data">12</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">8</p></div></a><a><div class="stat-container js-profile-coauthors" data-broccoli-component="user-info.coauthors-count" data-click-track="profile-expand-user-info-coauthors"><p class="label">Co-authors</p><p class="data">8</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="35639169" href="https://www.academia.edu/Documents/in/Mental_Causation"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/BaudouinByl","location":"/BaudouinByl","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/BaudouinByl","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Mental Causation"]}" data-trace="false" data-dom-id="Pill-react-component-154665e4-1bd5-4ee6-8e2a-a8f04eb2564c"></div> <div id="Pill-react-component-154665e4-1bd5-4ee6-8e2a-a8f04eb2564c"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="35639169" href="https://www.academia.edu/Documents/in/Epistemologia_Genetica"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Epistemologia Genética"]}" data-trace="false" data-dom-id="Pill-react-component-4b07fbed-e187-4dec-ae31-f6f9c1fdd08f"></div> <div id="Pill-react-component-4b07fbed-e187-4dec-ae31-f6f9c1fdd08f"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="35639169" href="https://www.academia.edu/Documents/in/Clinical_and_Molecular_Human_Genetics"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Clinical and Molecular Human Genetics"]}" data-trace="false" data-dom-id="Pill-react-component-f8d6a5b5-7eeb-403f-842c-050275ca3bbb"></div> <div id="Pill-react-component-f8d6a5b5-7eeb-403f-842c-050275ca3bbb"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="35639169" href="https://www.academia.edu/Documents/in/Farmacologia"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Farmacologia"]}" data-trace="false" data-dom-id="Pill-react-component-d17a1f17-082c-4077-9580-a73a59564e4a"></div> <div id="Pill-react-component-d17a1f17-082c-4077-9580-a73a59564e4a"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="35639169" href="https://www.academia.edu/Documents/in/Causation"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Causation"]}" data-trace="false" data-dom-id="Pill-react-component-b591076a-d355-4f1b-9156-ad7bf3ec7a61"></div> <div id="Pill-react-component-b591076a-d355-4f1b-9156-ad7bf3ec7a61"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Baudouin Byl</h3></div><div class="js-work-strip profile--work_container" data-work-id="124601176"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601176/_From_MRSA_to_MRSAs_in_general_practice_"><img alt="Research paper thumbnail of [From MRSA to MRSA's in general practice]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601176/_From_MRSA_to_MRSAs_in_general_practice_">[From MRSA to MRSA's in general practice]</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, Sep 1, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Methicilline resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare associate...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Methicilline resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare associated infections. Limited therapeutic options, the fact that MRSA disease burden do not replace but adds to the sensitive strains burden and its association with increased morbidity and mortality justify reinforced efforts in both prevention of transmission and treatment. Although transmission in acute hospital is decreasing in Belgium, general practitioners face actually to an important prevalence of carriage in nursing homes. Hand hygiene, promotion of prudent use of antimicrobial agents, MRSA surveillance and control are all preventive strategies whom improvement should result in control of MRSA transmission and progressive prevalence decrease in this particular setting. More recently, community acquired strains (CA-MRSA) harboring Panton Valentin Leucocidin were associated with skin and soft tissue among younger people, and livestock associated strains were identified as causing agents of infection in farmer population. CA-MRSA are now transmitted in general population and are causative agents of recurrent or chronic skin infections resistant to beta-lactamine. The diagnosis needs to be evoked in particular settings such as frequent close skin contact (sport, ...). CA-MRSA may also cause necrotising pneumonia. The general practitioner is a central actor in the battle against MRSA both in the field of prevention and treatment by the prudent use of antibiotics, the promotion of hand hygiene and associated specific measures and the accuracy to detect clinical situation evoking infection due to CA-MRSA in the general population.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601176; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601176]").text(description); $(".js-view-count[data-work-id=124601176]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601176; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601176']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601176, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601176]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601176,"title":"[From MRSA to MRSA's in general practice]","translated_title":"","metadata":{"abstract":"Methicilline resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare associated infections. 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Its main activity consi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601175"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601175"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601175; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601175]").text(description); $(".js-view-count[data-work-id=124601175]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601175; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601175']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601175, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601175]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601175,"title":"[The infective diseases clinic]","translated_title":"","metadata":{"abstract":"The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. 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However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601174"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601174"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601174; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601174]").text(description); $(".js-view-count[data-work-id=124601174]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601174; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601174']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601174, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601174]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601174,"title":"The Use of Antibody Specificity and Affinity in Determining the Protectiveness of Human Monoclonal Antibodies Against Fatal Infections with Nosocomial Gram-Negative Bacteria","translated_title":"","metadata":{"abstract":"Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to the classical treatment of fatal infections with antibiotic-resistant gram-negative bacteria. However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.","publication_date":{"day":null,"month":null,"year":1993,"errors":{}}},"translated_abstract":"Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to the classical treatment of fatal infections with antibiotic-resistant gram-negative bacteria. However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.","internal_url":"https://www.academia.edu/124601174/The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria","translated_internal_url":"","created_at":"2024-10-10T05:08:15.852-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":113903,"name":"Bacteria","url":"https://www.academia.edu/Documents/in/Bacteria"},{"id":136892,"name":"Immunization","url":"https://www.academia.edu/Documents/in/Immunization"},{"id":357811,"name":"Antibody","url":"https://www.academia.edu/Documents/in/Antibody"},{"id":766014,"name":"Monoclonal Antibody","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibody"}],"urls":[{"id":45080961,"url":"https://doi.org/10.1007/978-3-642-77405-8_158"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601173"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601173/The_role_of_the_pharmacist_in_improving_the_safety_of_chemotherapy_and_treatment_with_monoclonal_antibodies"><img alt="Research paper thumbnail of The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601173/The_role_of_the_pharmacist_in_improving_the_safety_of_chemotherapy_and_treatment_with_monoclonal_antibodies">The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies</a></div><div class="wp-workCard_item"><span>European Journal of Oncology Pharmacy</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases. These treatments continually evolve, calling on constant adaptation by healthcare workers. Despite what is known about the consequences of medication errors, and a growing safety culture, medication-related incidents are still detected by the pharmacist.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601173"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601173"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601173; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601173]").text(description); $(".js-view-count[data-work-id=124601173]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601173; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601173']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601173, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601173]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601173,"title":"The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies","translated_title":"","metadata":{"abstract":"Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601172"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601172/Determinants_of_methicillin_resistant_staphylococcus_aureus_carriage_among_hospitalized_geriatric_patients"><img alt="Research paper thumbnail of Determinants of methicillin-resistant staphylococcus aureus carriage among hospitalized geriatric patients" class="work-thumbnail" src="https://attachments.academia-assets.com/118797134/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601172/Determinants_of_methicillin_resistant_staphylococcus_aureus_carriage_among_hospitalized_geriatric_patients">Determinants of methicillin-resistant staphylococcus aureus carriage among hospitalized geriatric patients</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b58fc996a690663c462bac34cee62e4a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797134,"asset_id":124601172,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797134/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601172"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601172"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601172; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601172]").text(description); $(".js-view-count[data-work-id=124601172]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601172; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601172']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601172, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b58fc996a690663c462bac34cee62e4a" } } $('.js-work-strip[data-work-id=124601172]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601172,"title":"Determinants of methicillin-resistant staphylococcus aureus carriage among hospitalized geriatric patients","translated_title":"","metadata":{"grobid_abstract":"Published literature on methicillin-resistant Staphylococcus aureus (MRSA) in the Asia-Pacific region was reviewed to document the prevalence of MRSA in the region and to examine the impact of variability in study design on the reported MRSA prevalence data. Methods: This review included studies reporting MRSA prevalence between 2000 and 2016. Studies were excluded if they did not contain complete information on antimicrobial susceptibility testing (AST) methods. Primary outcomes were the proportion of MRSA among S. aureus isolates (resistance proportion) or among individual samples (prevalence). Results: A total of 229 studies in 19 countries/territories were included in the study. There was substantial heterogeneity in both outcomes (resistance proportion, I 2 = 99.59%; prevalence, I 2 = 99.83%), precluding pooled averages, and meta-regression analyses revealed that these variations were explained by country income status and participant characteristics but not by methodological differences in AST. Also, no significant secular changes in MRSA prevalence or resistance proportions in Asia-Pacific were found. Conclusion: The resistance proportions and prevalence of MRSA infections in Asia-Pacific are comparable with those reported in other regions with no significant secular changes in the past decade. Country income status and characteristics of the sample population explained more variation in the reported resistance proportions and prevalence of MRSA than methodological differences in AST across locations in the region.","publication_date":{"day":null,"month":null,"year":2005,"errors":{}},"grobid_abstract_attachment_id":118797134},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601172/Determinants_of_methicillin_resistant_staphylococcus_aureus_carriage_among_hospitalized_geriatric_patients","translated_internal_url":"","created_at":"2024-10-10T05:08:15.259-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797134,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797134/thumbnails/1.jpg","file_name":"j.jgar.2018.08.01420241010-1-o5q5rd.pdf","download_url":"https://www.academia.edu/attachments/118797134/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Determinants_of_methicillin_resistant_st.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797134/j.jgar.2018.08.01420241010-1-o5q5rd-libre.pdf?1728564904=\u0026response-content-disposition=attachment%3B+filename%3DDeterminants_of_methicillin_resistant_st.pdf\u0026Expires=1733038918\u0026Signature=R2dlTyhHsWcbMwcAS~qQ6saaAtHkk-HY01XbC1OGDh5onkZjMEzkJz2F1Yhee8amy6hdJO0NR0ur9T7mn~tIB2tAdltzy3N1KBXMnWt0DtQWFHOQw~anD-sd6qL1hp9JsSJ9CnJXjX5q8NO0gCE3evmv66VXlujeXTeeNKzto-4PgLQLMBJju2KNmvIUuDlK7EVEiTY5i~2kZEnCS9axm-PvZGgA6PCNcIhZUPDevMd9ZZKA6i6Zq08JC1eXM0l~bUzbMzjHwsC25xEvov~EchJ0MOwZXnDNh4aRDiyt-JGMow5x8AECkBnChXfV-QD81NaWZz0NptrWhJq4MXLiXw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Determinants_of_methicillin_resistant_staphylococcus_aureus_carriage_among_hospitalized_geriatric_patients","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[{"id":118797134,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797134/thumbnails/1.jpg","file_name":"j.jgar.2018.08.01420241010-1-o5q5rd.pdf","download_url":"https://www.academia.edu/attachments/118797134/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Determinants_of_methicillin_resistant_st.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797134/j.jgar.2018.08.01420241010-1-o5q5rd-libre.pdf?1728564904=\u0026response-content-disposition=attachment%3B+filename%3DDeterminants_of_methicillin_resistant_st.pdf\u0026Expires=1733038918\u0026Signature=R2dlTyhHsWcbMwcAS~qQ6saaAtHkk-HY01XbC1OGDh5onkZjMEzkJz2F1Yhee8amy6hdJO0NR0ur9T7mn~tIB2tAdltzy3N1KBXMnWt0DtQWFHOQw~anD-sd6qL1hp9JsSJ9CnJXjX5q8NO0gCE3evmv66VXlujeXTeeNKzto-4PgLQLMBJju2KNmvIUuDlK7EVEiTY5i~2kZEnCS9axm-PvZGgA6PCNcIhZUPDevMd9ZZKA6i6Zq08JC1eXM0l~bUzbMzjHwsC25xEvov~EchJ0MOwZXnDNh4aRDiyt-JGMow5x8AECkBnChXfV-QD81NaWZz0NptrWhJq4MXLiXw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":116078,"name":"Staphylococcus aureus","url":"https://www.academia.edu/Documents/in/Staphylococcus_aureus"},{"id":1381991,"name":"Methicillin Resistant Staphylococcus Aureus","url":"https://www.academia.edu/Documents/in/Methicillin_Resistant_Staphylococcus_Aureus"},{"id":2494432,"name":"Carriage","url":"https://www.academia.edu/Documents/in/Carriage"}],"urls":[{"id":45080959,"url":"https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/158828/Details"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601170"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601170/Antibiotic_Prophylaxis_before_Endoscopic_Retrograde_Cholangiopancreatography"><img alt="Research paper thumbnail of Antibiotic Prophylaxis before Endoscopic Retrograde Cholangiopancreatography" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601170/Antibiotic_Prophylaxis_before_Endoscopic_Retrograde_Cholangiopancreatography">Antibiotic Prophylaxis before Endoscopic Retrograde Cholangiopancreatography</a></div><div class="wp-workCard_item"><span>Annals of Internal Medicine</span><span>, Jun 15, 1997</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Page 1. The Editors welcome submissions for possible publication in the Letters section. Authors ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Page 1. The Editors welcome submissions for possible publication in the Letters section. 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The Editors welcome submissions for possible publication in the Letters section. Authors of letters should: Include no more than 300 words of text, three authors, and five references Type with double-spacing Send ...","publisher":"American College of Physicians","publication_date":{"day":15,"month":6,"year":1997,"errors":{}},"publication_name":"Annals of Internal Medicine"},"translated_abstract":"Page 1. The Editors welcome submissions for possible publication in the Letters section. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601168"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601168/Efficacy_of_the_decolonization_of_methicillin_resistant_Staphylococcus_aureus_carriers_in_clinical_practice"><img alt="Research paper thumbnail of Efficacy of the decolonization of methicillin-resistant Staphylococcus aureus carriers in clinical practice" class="work-thumbnail" src="https://attachments.academia-assets.com/118797133/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601168/Efficacy_of_the_decolonization_of_methicillin_resistant_Staphylococcus_aureus_carriers_in_clinical_practice">Efficacy of the decolonization of methicillin-resistant Staphylococcus aureus carriers in clinical practice</a></div><div class="wp-workCard_item"><span>Antimicrobial Resistance and Infection Control</span><span>, Dec 1, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2d39397e55e0057b0f14dafe936396ea" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797133,"asset_id":124601168,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797133/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601168"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601168"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601168; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601168]").text(description); $(".js-view-count[data-work-id=124601168]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601168; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601168']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601168, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2d39397e55e0057b0f14dafe936396ea" } } $('.js-work-strip[data-work-id=124601168]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601168,"title":"Efficacy of the decolonization of methicillin-resistant Staphylococcus aureus carriers in clinical practice","translated_title":"","metadata":{"publisher":"BioMed Central","grobid_abstract":"Background: Nasal and extra nasal carriage of methicillin-resistant S. aureus (MRSA) is a pre-existing condition that often leads to invasive MRSA infection, as MRSA colonization is associated with a high risk of acquiring MRSA infection during hospital stays. Decolonization may reduce the risk of meticillin-resistant Staphylococcus aureus (MRSA) infection in individual carriers and prevent transmission to other patients. Methods: A retrospective cohort study was conducted to evaluate the effectiveness of two decolonization protocols for newly diagnosed MRSA carriage in hospitalized patients and to assess the impact of decolonization on the rate of MRSA infection. The study population consisted of all patients diagnosed as MRSA-positive between January 2006 and June 2010. Patients diagnosed as carriers were designated as requiring contact precautions by the hospital infection control team. The standing order protocol of the hospital pertaining to decolonization procedures was then applied, and all newly diagnosed patients were administered one of the two decolonization treatments outlined in the hospital protocol, with the exception of MRSA respiratory carriers (MRSA obtained from sputum or other lower respiratory tract samples). The two decolonization treatments consisted of the application of intranasal mupirocin 2 % and washing with chlorhexidine soap (40 mg/mL) (mupi/CHX) or application of intranasal povidone-iodine and washing with povidone-iodine soap (PVPI), with each treatment lasting for 5 days. Success was determined by at least three successive nose swabs and throat and other screened site swabs that tested negative for MRSA before patient discharge. Results: A total of 1150 patients admitted to the hospital were found to be infected or colonized with MRSA. Of the 1150 patients, 268 were prescribed decolonization treatment. 104 out of 268 patients (39 %) were successfully decolonized. There was no significant success after two decolonization failures. MRSA infection rate among the successes and failures were 0.0 and 4.3 %, respectively [P = 0.04]. Conclusions: Our results fit well with the prescription of decolonization based on local strategy protocols but reflect a low rate of successful treatment. 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Their claimed origin was India (n=11), DR Congo (n=5), France (n=4), Kenya (n=1), China (n=1), Germany(n=1), and Switzerland (n=1). The specimens were checked for falsifications following the WHO checklist. Content identity and amount of antibiotics in the specimens was investigated by Ultra High Performance Liquid Chromatography coupled with tandem mass spectrophotometry (UHPLC-MS/MS) and diode array detection (UHPLC-DAD). Nine of the 24 samples fulfilled the WHO criteria of counterfeit drugs, but all samples contained the active ingredients as claimed on the packages. We found under dosage of 90% and less in 3 of the 15 amoxicillin samples and in none of the 9 combined specimens. Amoxicillin over dosage (defined as 110% or more of indicated content) was found in 3 of the amoxicillin and in 1 of the combined specimens. Clavulanic acid was underdosed in none but overdosed in 5 of the 9 combined specimens. Our results highlight the need for drug quality control through inspection and specific analytical methods such as spectrophotometry and chromatography to reduce the public health challenge of illegal and substandard medicines in sub-Saharan Africa.","publication_name":"African Journal of Pharmaceutical Sciences","grobid_abstract_attachment_id":118797131},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601167/Contents_of_Amoxicillin_Drugs_Dispensed_in_Goma_Democratic_Republic_of_Congo","translated_internal_url":"","created_at":"2024-10-10T05:08:13.891-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797131,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797131/thumbnails/1.jpg","file_name":"afjps.2.1.2022.pdf","download_url":"https://www.academia.edu/attachments/118797131/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Contents_of_Amoxicillin_Drugs_Dispensed.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797131/afjps.2.1.2022-libre.pdf?1728564898=\u0026response-content-disposition=attachment%3B+filename%3DContents_of_Amoxicillin_Drugs_Dispensed.pdf\u0026Expires=1733038918\u0026Signature=Ua6YNJeIB1OLAzHJr7pY8XbksZleUnmcveYXl7vDbvj0vPRdpxFlHm8Uf8eNUeK-LH7xcHytDwVRrPyq4vTa3HwfPzoJaBnMRH6QFs18JbckNPIUn2NTS5NtUm2QcczS3rbB7KWfa~bIyB0rANQsDkZxcbEed2YxAILxJZlC-HA2FgJR1u8l5gI1nz12wFTe0RIMM2ou~Q9bIXzrVRXsnurZzIg2BDKEQaPez0C1f0Vzy2Fv2ydlo7etrfhJydZBO4V~Z8CbW-BILjkp7DM2c0rLehUTSUJnc2njSrXgX8xELDKWEReFVomD4F3Zc7Xk-8VDszgta4Rztl-4l2F3rw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Contents_of_Amoxicillin_Drugs_Dispensed_in_Goma_Democratic_Republic_of_Congo","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[{"id":118797131,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797131/thumbnails/1.jpg","file_name":"afjps.2.1.2022.pdf","download_url":"https://www.academia.edu/attachments/118797131/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Contents_of_Amoxicillin_Drugs_Dispensed.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797131/afjps.2.1.2022-libre.pdf?1728564898=\u0026response-content-disposition=attachment%3B+filename%3DContents_of_Amoxicillin_Drugs_Dispensed.pdf\u0026Expires=1733038918\u0026Signature=Ua6YNJeIB1OLAzHJr7pY8XbksZleUnmcveYXl7vDbvj0vPRdpxFlHm8Uf8eNUeK-LH7xcHytDwVRrPyq4vTa3HwfPzoJaBnMRH6QFs18JbckNPIUn2NTS5NtUm2QcczS3rbB7KWfa~bIyB0rANQsDkZxcbEed2YxAILxJZlC-HA2FgJR1u8l5gI1nz12wFTe0RIMM2ou~Q9bIXzrVRXsnurZzIg2BDKEQaPez0C1f0Vzy2Fv2ydlo7etrfhJydZBO4V~Z8CbW-BILjkp7DM2c0rLehUTSUJnc2njSrXgX8xELDKWEReFVomD4F3Zc7Xk-8VDszgta4Rztl-4l2F3rw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"},{"id":17123,"name":"Democracy","url":"https://www.academia.edu/Documents/in/Democracy"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":382521,"name":"Amoxicillin","url":"https://www.academia.edu/Documents/in/Amoxicillin"},{"id":897663,"name":"Congo Red","url":"https://www.academia.edu/Documents/in/Congo_Red"}],"urls":[]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601163"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601163/_The_infective_diseases_clinic_"><img alt="Research paper thumbnail of [The infective diseases clinic]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601163/_The_infective_diseases_clinic_">[The infective diseases clinic]</a></div><div class="wp-workCard_item"><span>Revue médicale de Bruxelles</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. 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In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601162"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601162"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601162; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601162]").text(description); $(".js-view-count[data-work-id=124601162]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601162; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601162']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601162, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601162]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601162,"title":"[The hospital epidemiology and hygiene unit]","translated_title":"","metadata":{"abstract":"The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and controlling epidemics. In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Revue médicale de Bruxelles"},"translated_abstract":"The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and controlling epidemics. In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.","internal_url":"https://www.academia.edu/124601162/_The_hospital_epidemiology_and_hygiene_unit_","translated_internal_url":"","created_at":"2024-10-10T05:08:13.157-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_The_hospital_epidemiology_and_hygiene_unit_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium"},{"id":66744,"name":"Biomedical Research","url":"https://www.academia.edu/Documents/in/Biomedical_Research"},{"id":69637,"name":"Infection Control","url":"https://www.academia.edu/Documents/in/Infection_Control"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":201203,"name":"Hygiene","url":"https://www.academia.edu/Documents/in/Hygiene"},{"id":251655,"name":"Antibiotics","url":"https://www.academia.edu/Documents/in/Antibiotics"},{"id":568312,"name":"Intensive Care Medicine","url":"https://www.academia.edu/Documents/in/Intensive_Care_Medicine"},{"id":871724,"name":"University Hospitals","url":"https://www.academia.edu/Documents/in/University_Hospitals"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601161"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study"><img alt="Research paper thumbnail of Human herpesvirus-6 infection after lung and heart-lung transplantation: a prospective longitudinal study" class="work-thumbnail" src="https://attachments.academia-assets.com/118797139/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study">Human herpesvirus-6 infection after lung and heart-lung transplantation: a prospective longitudinal study</a></div><div class="wp-workCard_item"><span>Transplantation</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="1c78567a3b6ecb1e6256131c1caf277d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797139,"asset_id":124601161,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797139/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601161"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601161"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601161; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601161]").text(description); $(".js-view-count[data-work-id=124601161]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601161; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601161']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601161, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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Although human herpesvirus (HHV)-6 is now recognized as a frequent pathogen after transplantation, the real impact of this infection in patients undergoing transplantation remains unclear. Methods. During 27 months, 30 consecutive heartlung-and lung-transplant recipients were included on the day of transplantation and prospectively followed during 100 days for HHV-6 infection. Results. HHV-6 infection occurred in 20 (66%) patients after a median delay of 18 days after transplantation. The virus was detected by polymerase chain reaction or culture, or both, in 15.7 % of blood specimens, in 14.5% of bronchoalveolar lavage fluids, and in many organs at postmortem examination; it was found by culture in eight patients. No clinical manifestations could clearly be associated with HHV-6 alone. However, patients with HHV-6 infection had a higher mortality rate than patients without HHV-6 infection (7 of 20 vs. 0 of 10; P‫,)40.0؍‬ and all the deceased patients died during periods of HHV-6 infection. We did not observe higher incidence of infectious or graft-rejection episodes in HHV-6-positive patients. However, eight of nine viral or fungal infections occurred during HHV-6 infection and three were directly responsible for death. Conclusion. Although frequently detected after transplantation, HHV-6 was not associated with any specific clinical manifestation. The higher mortality rate observed in patients with HHV-6 infection was not related to a higher incidence of bacterial infections or graft rejection but might be associated with more viral and fungal infections.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Transplantation","grobid_abstract_attachment_id":118797139},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study","translated_internal_url":"","created_at":"2024-10-10T05:08:12.889-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797139,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797139/thumbnails/1.jpg","file_name":"01.tp.0000058809.42027.6620241010-1-oth6ub.pdf","download_url":"https://www.academia.edu/attachments/118797139/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Human_herpesvirus_6_infection_after_lung.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797139/01.tp.0000058809.42027.6620241010-1-oth6ub-libre.pdf?1728564882=\u0026response-content-disposition=attachment%3B+filename%3DHuman_herpesvirus_6_infection_after_lung.pdf\u0026Expires=1733038918\u0026Signature=EWAC27fnuIwCxXwfk~z3s7-LeeLnjm4O7oU7wUORhUxwUmOOZprhXSVDKMYsV~SP8TmkWlzkOKHZApu42MbFXW4WEFQmU-VfC0J~m8tuxZd6XxTYb2h9c1UOzxubel0CAFjcG9-3xqYAQFdLppd3W-~gOFWIYgaINedoa2ODicrtgr3KH-s8eujr6TMAcwlhTLMPFng~37roEJ3K8kfK7d5Js8z6oCSoE7nnawkTaO63p6aKN18E6n~HyJyHMYj8Bau0R7p4NRy2P-D7wnu6WOwLVfHCdOdAcSqSj51yG2K6xh4bLA7mI9GVGldnsR-U9wdBNpp5QJ4rxO4HogAfLg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601160"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient"><img alt="Research paper thumbnail of Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient" class="work-thumbnail" src="https://attachments.academia-assets.com/118797135/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient">Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient</a></div><div class="wp-workCard_item"><span>Transplantation</span><span>, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="fcb2eb6934ad572cfa564064954e4fca" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797135,"asset_id":124601160,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601160"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601160"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601160; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601160]").text(description); $(".js-view-count[data-work-id=124601160]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId 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_.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "fcb2eb6934ad572cfa564064954e4fca" } } $('.js-work-strip[data-work-id=124601160]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601160,"title":"Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient","translated_title":"","metadata":{"publisher":"Ovid Technologies (Wolters Kluwer Health)","grobid_abstract":"We describe a fatal primary human herpesvirus 6 (HHV-6) variant A infection in a kidney transplanted adult woman. On day 20 post transplantation (TX), after rejection therapy, the patient presented an acute hemophagocytic syndrome with hepatitis and central nervous system involvement. HHV-6 IgG and IgM antibodies seroconversion was demonstrated. HHV-6 variant A was the sole pathogen detected by nested PCR and/or culture in blood, bone marrow aspiration, liver biopsy, cerebrospinal fluid and bronchoalveolar lavage. The graft was HHV-6 seropositive and the patient was not transfused before day 28 post TX, suggesting that the virus was transmitted by the graft. Despite immunoglobulins, ganciclovir and foscarnet therapy, the HHV-6 infection progressed and led to severe aplasia. The patient developed Aspergillus fumigatus pneumonia and died from fulminant candidemia. This case demonstrated for the first time that HHV-6 variant A primary infection can cause lifethreatening disseminated infection in immunosuppressed patients.","publication_date":{"day":null,"month":null,"year":2001,"errors":{}},"publication_name":"Transplantation","grobid_abstract_attachment_id":118797135},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient","translated_internal_url":"","created_at":"2024-10-10T05:08:12.459-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797135,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797135/thumbnails/1.jpg","file_name":"00007890-200101270-0002120241010-1-ohz7gj.pdf","download_url":"https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Fatal_Primary_Infection_Due_to_Human_Her.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797135/00007890-200101270-0002120241010-1-ohz7gj-libre.pdf?1728564884=\u0026response-content-disposition=attachment%3B+filename%3DFatal_Primary_Infection_Due_to_Human_Her.pdf\u0026Expires=1733038918\u0026Signature=LCVXzVDcAhbepo2uloQT1yM9cRJAGfgvi3ux00P8Lkf2nPU1CyFVmwPA3O9HAX8OSEofmuZB9AsMKe7LFX33ww8B-2DcpZcMXb70S~lxXwvHcRlL4d1SABYtFyD~Im0uN04LFxWLfZJTR~qLjni6M5dvXVeRd1uDH~RizfhQjasXyIwjqs~WC5VzAwQL2UIfxfoL4jsgtm~6UflMDsEXpc9~qv8iQODGkOrav1IzPJeiVQeRKv62~sKFYWiU36mKeb91HtiECZRQAGyCLD8R7dOK-ZLTcbU8wahxWx1-fC6V5ZLbyURocXu-8kiPjt47Z9zILwNYRHLM9WnvCdDUkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[{"id":118797135,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797135/thumbnails/1.jpg","file_name":"00007890-200101270-0002120241010-1-ohz7gj.pdf","download_url":"https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Fatal_Primary_Infection_Due_to_Human_Her.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797135/00007890-200101270-0002120241010-1-ohz7gj-libre.pdf?1728564884=\u0026response-content-disposition=attachment%3B+filename%3DFatal_Primary_Infection_Due_to_Human_Her.pdf\u0026Expires=1733038918\u0026Signature=LCVXzVDcAhbepo2uloQT1yM9cRJAGfgvi3ux00P8Lkf2nPU1CyFVmwPA3O9HAX8OSEofmuZB9AsMKe7LFX33ww8B-2DcpZcMXb70S~lxXwvHcRlL4d1SABYtFyD~Im0uN04LFxWLfZJTR~qLjni6M5dvXVeRd1uDH~RizfhQjasXyIwjqs~WC5VzAwQL2UIfxfoL4jsgtm~6UflMDsEXpc9~qv8iQODGkOrav1IzPJeiVQeRKv62~sKFYWiU36mKeb91HtiECZRQAGyCLD8R7dOK-ZLTcbU8wahxWx1-fC6V5ZLbyURocXu-8kiPjt47Z9zILwNYRHLM9WnvCdDUkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":9003,"name":"Kidney transplantation","url":"https://www.academia.edu/Documents/in/Kidney_transplantation"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":51530,"name":"Transplantation","url":"https://www.academia.edu/Documents/in/Transplantation"},{"id":385972,"name":"Immunocompromised host","url":"https://www.academia.edu/Documents/in/Immunocompromised_host"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"},{"id":577933,"name":"Genetic variation","url":"https://www.academia.edu/Documents/in/Genetic_variation"},{"id":1495798,"name":"Fulminant","url":"https://www.academia.edu/Documents/in/Fulminant"},{"id":2056374,"name":"Seroconversion","url":"https://www.academia.edu/Documents/in/Seroconversion"},{"id":2422514,"name":"Foscarnet","url":"https://www.academia.edu/Documents/in/Foscarnet"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"},{"id":4055611,"name":"Fatal outcome","url":"https://www.academia.edu/Documents/in/Fatal_outcome"}],"urls":[{"id":45080953,"url":"http://journals.lww.com/00007890-200101270-00021"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601159"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601159/Outbreak_of_hospital_adapted_clonal_complex_17_vancomycin_resistant_Enterococcus_faecium_strain_in_a_haematology_unit_role_of_rapid_typing_for_early_control"><img alt="Research paper thumbnail of Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control" class="work-thumbnail" src="https://attachments.academia-assets.com/118797141/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601159/Outbreak_of_hospital_adapted_clonal_complex_17_vancomycin_resistant_Enterococcus_faecium_strain_in_a_haematology_unit_role_of_rapid_typing_for_early_control">Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control</a></div><div class="wp-workCard_item"><span>Journal of Antimicrobial Chemotherapy</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a366e82208cefc5474d062e69f07070f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797141,"asset_id":124601159,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797141/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601159"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601159"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601159; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601159]").text(description); $(".js-view-count[data-work-id=124601159]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601159; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601159']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601159, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "a366e82208cefc5474d062e69f07070f" } } $('.js-work-strip[data-work-id=124601159]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601159,"title":"Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"To describe the investigation and molecular characterization of a vancomycin-resistant Enterococcus faecium (VREF) strain responsible for a nosocomial outbreak in the haematology unit of a tertiary-care university hospital. Patients and methods: Two patients admitted to the haematology unit developed infection/colonization with VREF over a 3 month period when compared with none in the 2 previous years. On the basis of the identification of a clonal link between these two strains, weekly rectal screening was implemented for all patients in the haematology unit and contact precautions were extended to VREF carriers. In the following 6 month period, 11 patients colonized with VREF were detected. No further case was detected in the following 1 year period. Results: VREF isolates from the haematology unit carried the vanA gene and were multiresistant to antimicrobial agents, including high-level resistance to vancomycin, teicoplanin and ampicillin. This resistance profile restricted the choice of antimicrobial therapy to linezolid or investigational drugs such as tigecycline. Molecular analysis showed that 11 of 13 (85%) VREF isolates belonged to pandemic clonal complex-17 carrying the esp and hyl virulence genes. Conclusions: Rapid typing and infection control measures, including early reinforcement of barrier precautions combined with weekly rectal surveillance cultures, were followed by control of nosocomial spread of this VREF clone.","publication_date":{"day":null,"month":null,"year":2007,"errors":{}},"publication_name":"Journal of Antimicrobial 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data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601158/Is_Compliance_with_Hand_Disinfection_in_the_Intensive_Care_Unit_Related_to_Work_Experience">Is Compliance with Hand Disinfection in the Intensive Care Unit Related to Work Experience?</a></div><div class="wp-workCard_item"><span>Infection Control & Hospital Epidemiology</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The performance of hand disinfection by staff in a 31-bed department of intensive care was monito...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The performance of hand disinfection by staff in a 31-bed department of intensive care was monitored. During 32 hours of observation, 727 opportunities for hand disinfection were observed, and the compliance rate was 27.9%. The level of work experience was not correlated with hand disinfection compliance rates.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601158"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601158"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601158; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601158]").text(description); $(".js-view-count[data-work-id=124601158]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601158; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601158']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601158, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601158]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601158,"title":"Is Compliance with Hand Disinfection in the Intensive Care Unit Related to Work Experience?","translated_title":"","metadata":{"abstract":"The performance of hand disinfection by staff in a 31-bed department of intensive care was monitored. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="122588593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/122588593/Impact_de_la_pand%C3%A9mie_A_H1N1_v2009_sur_le_fonctionnement_d_un_h%C3%B4pital_aigu_Bruxelles_Belgique"><img alt="Research paper thumbnail of Impact de la pandémie A(H1N1)v2009 sur le fonctionnement d’un hôpital aigu, Bruxelles, Belgique" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/122588593/Impact_de_la_pand%C3%A9mie_A_H1N1_v2009_sur_le_fonctionnement_d_un_h%C3%B4pital_aigu_Bruxelles_Belgique">Impact de la pandémie A(H1N1)v2009 sur le fonctionnement d’un hôpital aigu, Bruxelles, Belgique</a></div><div class="wp-workCard_item"><span>Revue D Epidemiologie Et De Sante Publique</span><span>, Sep 1, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="122588593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="122588593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 122588593; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=122588593]").text(description); $(".js-view-count[data-work-id=122588593]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 122588593; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='122588593']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 122588593, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="116422115"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/116422115/Ciprofloxacin_vs_Comparative_Antibiotics_in_LRTI"><img alt="Research paper thumbnail of Ciprofloxacin vs Comparative Antibiotics in LRTI" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/116422115/Ciprofloxacin_vs_Comparative_Antibiotics_in_LRTI">Ciprofloxacin vs Comparative Antibiotics in LRTI</a></div><div class="wp-workCard_item"><span>Drugs</span><span>, 1993</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In view of the excellent antimicrobial activity of ciprofloxacin against most respiratory pathoge...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In view of the excellent antimicrobial activity of ciprofloxacin against most respiratory pathogens and its good penetration into respiratory tissues and fluids, this drug has been extensively used for the treatment of lower respiratory tract infections (LRTI). However, the number of patients in most of the comparative trials was too small to enable a significant difference in efficacy between ciprofloxacin and the comparative drugs to be detected. This study evaluated the efficacy of ciprofloxacin versus other drugs in the treatment of LR n, using an unblinded meta-analysis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="116422115"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="116422115"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 116422115; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=116422115]").text(description); $(".js-view-count[data-work-id=116422115]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 116422115; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='116422115']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 116422115, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=116422115]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":116422115,"title":"Ciprofloxacin vs Comparative Antibiotics in LRTI","translated_title":"","metadata":{"abstract":"In view of the excellent antimicrobial activity of ciprofloxacin against most respiratory pathogens and its good penetration into respiratory tissues and fluids, this drug has been extensively used for the treatment of lower respiratory tract infections (LRTI). 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Limited therapeutic options, the fact that MRSA disease burden do not replace but adds to the sensitive strains burden and its association with increased morbidity and mortality justify reinforced efforts in both prevention of transmission and treatment. Although transmission in acute hospital is decreasing in Belgium, general practitioners face actually to an important prevalence of carriage in nursing homes. Hand hygiene, promotion of prudent use of antimicrobial agents, MRSA surveillance and control are all preventive strategies whom improvement should result in control of MRSA transmission and progressive prevalence decrease in this particular setting. More recently, community acquired strains (CA-MRSA) harboring Panton Valentin Leucocidin were associated with skin and soft tissue among younger people, and livestock associated strains were identified as causing agents of infection in farmer population. CA-MRSA are now transmitted in general population and are causative agents of recurrent or chronic skin infections resistant to beta-lactamine. The diagnosis needs to be evoked in particular settings such as frequent close skin contact (sport, ...). CA-MRSA may also cause necrotising pneumonia. The general practitioner is a central actor in the battle against MRSA both in the field of prevention and treatment by the prudent use of antibiotics, the promotion of hand hygiene and associated specific measures and the accuracy to detect clinical situation evoking infection due to CA-MRSA in the general population.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601176; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601176]").text(description); $(".js-view-count[data-work-id=124601176]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601176; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601176']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601176, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601176]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601176,"title":"[From MRSA to MRSA's in general practice]","translated_title":"","metadata":{"abstract":"Methicilline resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare associated infections. Limited therapeutic options, the fact that MRSA disease burden do not replace but adds to the sensitive strains burden and its association with increased morbidity and mortality justify reinforced efforts in both prevention of transmission and treatment. Although transmission in acute hospital is decreasing in Belgium, general practitioners face actually to an important prevalence of carriage in nursing homes. Hand hygiene, promotion of prudent use of antimicrobial agents, MRSA surveillance and control are all preventive strategies whom improvement should result in control of MRSA transmission and progressive prevalence decrease in this particular setting. More recently, community acquired strains (CA-MRSA) harboring Panton Valentin Leucocidin were associated with skin and soft tissue among younger people, and livestock associated strains were identified as causing agents of infection in farmer population. CA-MRSA are now transmitted in general population and are causative agents of recurrent or chronic skin infections resistant to beta-lactamine. The diagnosis needs to be evoked in particular settings such as frequent close skin contact (sport, ...). CA-MRSA may also cause necrotising pneumonia. The general practitioner is a central actor in the battle against MRSA both in the field of prevention and treatment by the prudent use of antibiotics, the promotion of hand hygiene and associated specific measures and the accuracy to detect clinical situation evoking infection due to CA-MRSA in the general population.","publication_date":{"day":1,"month":9,"year":2011,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"Methicilline resistant Staphylococcus aureus (MRSA) remains a major cause of healthcare associated infections. Limited therapeutic options, the fact that MRSA disease burden do not replace but adds to the sensitive strains burden and its association with increased morbidity and mortality justify reinforced efforts in both prevention of transmission and treatment. Although transmission in acute hospital is decreasing in Belgium, general practitioners face actually to an important prevalence of carriage in nursing homes. Hand hygiene, promotion of prudent use of antimicrobial agents, MRSA surveillance and control are all preventive strategies whom improvement should result in control of MRSA transmission and progressive prevalence decrease in this particular setting. More recently, community acquired strains (CA-MRSA) harboring Panton Valentin Leucocidin were associated with skin and soft tissue among younger people, and livestock associated strains were identified as causing agents of infection in farmer population. CA-MRSA are now transmitted in general population and are causative agents of recurrent or chronic skin infections resistant to beta-lactamine. The diagnosis needs to be evoked in particular settings such as frequent close skin contact (sport, ...). CA-MRSA may also cause necrotising pneumonia. 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Its main activity consi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601175"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601175"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601175; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601175]").text(description); $(".js-view-count[data-work-id=124601175]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601175; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601175']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601175, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601175]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601175,"title":"[The infective diseases clinic]","translated_title":"","metadata":{"abstract":"The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.","internal_url":"https://www.academia.edu/124601175/_The_infective_diseases_clinic_","translated_internal_url":"","created_at":"2024-10-10T05:08:16.080-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_The_infective_diseases_clinic_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":13734,"name":"Communicable Diseases","url":"https://www.academia.edu/Documents/in/Communicable_Diseases"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":125076,"name":"Sepsis","url":"https://www.academia.edu/Documents/in/Sepsis"},{"id":179934,"name":"Vaccination","url":"https://www.academia.edu/Documents/in/Vaccination"},{"id":220036,"name":"Antimicrobial","url":"https://www.academia.edu/Documents/in/Antimicrobial"},{"id":568312,"name":"Intensive Care Medicine","url":"https://www.academia.edu/Documents/in/Intensive_Care_Medicine"},{"id":871724,"name":"University Hospitals","url":"https://www.academia.edu/Documents/in/University_Hospitals"}],"urls":[{"id":45080962,"url":"https://pubmed.ncbi.nlm.nih.gov/12584921"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601174"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601174/The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria"><img alt="Research paper thumbnail of The Use of Antibody Specificity and Affinity in Determining the Protectiveness of Human Monoclonal Antibodies Against Fatal Infections with Nosocomial Gram-Negative Bacteria" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601174/The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria">The Use of Antibody Specificity and Affinity in Determining the Protectiveness of Human Monoclonal Antibodies Against Fatal Infections with Nosocomial Gram-Negative Bacteria</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to the classical treatment of fatal infections with antibiotic-resistant gram-negative bacteria. However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601174"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601174"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601174; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601174]").text(description); $(".js-view-count[data-work-id=124601174]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601174; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601174']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601174, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601174]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601174,"title":"The Use of Antibody Specificity and Affinity in Determining the Protectiveness of Human Monoclonal Antibodies Against Fatal Infections with Nosocomial Gram-Negative Bacteria","translated_title":"","metadata":{"abstract":"Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to the classical treatment of fatal infections with antibiotic-resistant gram-negative bacteria. However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.","publication_date":{"day":null,"month":null,"year":1993,"errors":{}}},"translated_abstract":"Passive immunization with human monoclonal antibodies (mAb) may become a feasible alternative to the classical treatment of fatal infections with antibiotic-resistant gram-negative bacteria. However, the search for and the generation of therapeutically active human mAb depends upon an improvement in the understanding of the immunological basis of protection.","internal_url":"https://www.academia.edu/124601174/The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria","translated_internal_url":"","created_at":"2024-10-10T05:08:15.852-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Use_of_Antibody_Specificity_and_Affinity_in_Determining_the_Protectiveness_of_Human_Monoclonal_Antibodies_Against_Fatal_Infections_with_Nosocomial_Gram_Negative_Bacteria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":113903,"name":"Bacteria","url":"https://www.academia.edu/Documents/in/Bacteria"},{"id":136892,"name":"Immunization","url":"https://www.academia.edu/Documents/in/Immunization"},{"id":357811,"name":"Antibody","url":"https://www.academia.edu/Documents/in/Antibody"},{"id":766014,"name":"Monoclonal Antibody","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibody"}],"urls":[{"id":45080961,"url":"https://doi.org/10.1007/978-3-642-77405-8_158"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601173"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601173/The_role_of_the_pharmacist_in_improving_the_safety_of_chemotherapy_and_treatment_with_monoclonal_antibodies"><img alt="Research paper thumbnail of The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601173/The_role_of_the_pharmacist_in_improving_the_safety_of_chemotherapy_and_treatment_with_monoclonal_antibodies">The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies</a></div><div class="wp-workCard_item"><span>European Journal of Oncology Pharmacy</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases. These treatments continually evolve, calling on constant adaptation by healthcare workers. Despite what is known about the consequences of medication errors, and a growing safety culture, medication-related incidents are still detected by the pharmacist.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601173"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601173"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601173; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601173]").text(description); $(".js-view-count[data-work-id=124601173]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601173; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601173']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601173, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601173]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601173,"title":"The role of the pharmacist in improving the safety of chemotherapy and treatment with monoclonal antibodies","translated_title":"","metadata":{"abstract":"Introduction: Chemotherapy and monoclonal antibodies are used increasingly to treat many diseases. 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Methods: This review included studies reporting MRSA prevalence between 2000 and 2016. Studies were excluded if they did not contain complete information on antimicrobial susceptibility testing (AST) methods. Primary outcomes were the proportion of MRSA among S. aureus isolates (resistance proportion) or among individual samples (prevalence). Results: A total of 229 studies in 19 countries/territories were included in the study. There was substantial heterogeneity in both outcomes (resistance proportion, I 2 = 99.59%; prevalence, I 2 = 99.83%), precluding pooled averages, and meta-regression analyses revealed that these variations were explained by country income status and participant characteristics but not by methodological differences in AST. Also, no significant secular changes in MRSA prevalence or resistance proportions in Asia-Pacific were found. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601170"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601170/Antibiotic_Prophylaxis_before_Endoscopic_Retrograde_Cholangiopancreatography"><img alt="Research paper thumbnail of Antibiotic Prophylaxis before Endoscopic Retrograde Cholangiopancreatography" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601170/Antibiotic_Prophylaxis_before_Endoscopic_Retrograde_Cholangiopancreatography">Antibiotic Prophylaxis before Endoscopic Retrograde Cholangiopancreatography</a></div><div class="wp-workCard_item"><span>Annals of Internal Medicine</span><span>, Jun 15, 1997</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Page 1. The Editors welcome submissions for possible publication in the Letters section. Authors ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Page 1. The Editors welcome submissions for possible publication in the Letters section. 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The Editors welcome submissions for possible publication in the Letters section. Authors of letters should: Include no more than 300 words of text, three authors, and five references Type with double-spacing Send ...","publisher":"American College of Physicians","publication_date":{"day":15,"month":6,"year":1997,"errors":{}},"publication_name":"Annals of Internal Medicine"},"translated_abstract":"Page 1. The Editors welcome submissions for possible publication in the Letters section. 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Decolonization may reduce the risk of meticillin-resistant Staphylococcus aureus (MRSA) infection in individual carriers and prevent transmission to other patients. Methods: A retrospective cohort study was conducted to evaluate the effectiveness of two decolonization protocols for newly diagnosed MRSA carriage in hospitalized patients and to assess the impact of decolonization on the rate of MRSA infection. The study population consisted of all patients diagnosed as MRSA-positive between January 2006 and June 2010. Patients diagnosed as carriers were designated as requiring contact precautions by the hospital infection control team. The standing order protocol of the hospital pertaining to decolonization procedures was then applied, and all newly diagnosed patients were administered one of the two decolonization treatments outlined in the hospital protocol, with the exception of MRSA respiratory carriers (MRSA obtained from sputum or other lower respiratory tract samples). The two decolonization treatments consisted of the application of intranasal mupirocin 2 % and washing with chlorhexidine soap (40 mg/mL) (mupi/CHX) or application of intranasal povidone-iodine and washing with povidone-iodine soap (PVPI), with each treatment lasting for 5 days. Success was determined by at least three successive nose swabs and throat and other screened site swabs that tested negative for MRSA before patient discharge. Results: A total of 1150 patients admitted to the hospital were found to be infected or colonized with MRSA. Of the 1150 patients, 268 were prescribed decolonization treatment. 104 out of 268 patients (39 %) were successfully decolonized. There was no significant success after two decolonization failures. MRSA infection rate among the successes and failures were 0.0 and 4.3 %, respectively [P = 0.04]. Conclusions: Our results fit well with the prescription of decolonization based on local strategy protocols but reflect a low rate of successful treatment. Although the success rate of decolonization was not high in our study, the effectiveness of decolonization on the infection rate, justifies the continuation of this strategy, even if a marginal cost is incurred.","publication_date":{"day":1,"month":12,"year":2015,"errors":{}},"publication_name":"Antimicrobial Resistance and Infection Control","grobid_abstract_attachment_id":118797133},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601168/Efficacy_of_the_decolonization_of_methicillin_resistant_Staphylococcus_aureus_carriers_in_clinical_practice","translated_internal_url":"","created_at":"2024-10-10T05:08:14.074-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797133/thumbnails/1.jpg","file_name":"s13756-015-0096-x.pdf","download_url":"https://www.academia.edu/attachments/118797133/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficacy_of_the_decolonization_of_methic.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797133/s13756-015-0096-x-libre.pdf?1728564898=\u0026response-content-disposition=attachment%3B+filename%3DEfficacy_of_the_decolonization_of_methic.pdf\u0026Expires=1733038918\u0026Signature=Zxb8jTwGCWkbU-LYiRCdNKL8TR5g1~8Xtx0qWZAEWa9ogsFVuNmlvMLiuezCPHRUK59lrxvXG1lZau65bA3FeV6XJEjDNlGe7dX4-d56H90Q8GH9FAAmZm~xxJVc2Ir91LcghZpNP~W1zZLxByVlOgDQthODcCUmrbHvbjZeoJrSdRygowP0lGOD6SGBiw96ERNEIc2wlnKzNHWwzbVT3nATj9Uyd-BNcnQSj6Er6oUUplpjEXpuTri3TX1G7fOags9-~Ew7rhLvDqCgReK3kBpicKNQ-3z83ZmaWA5Jj~xWmst5TKCyJJ8L5iqIqRAc69G3jkxTGSlrBAbq9pgP2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Efficacy_of_the_decolonization_of_methicillin_resistant_Staphylococcus_aureus_carriers_in_clinical_practice","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[{"id":118797133,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797133/thumbnails/1.jpg","file_name":"s13756-015-0096-x.pdf","download_url":"https://www.academia.edu/attachments/118797133/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficacy_of_the_decolonization_of_methic.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797133/s13756-015-0096-x-libre.pdf?1728564898=\u0026response-content-disposition=attachment%3B+filename%3DEfficacy_of_the_decolonization_of_methic.pdf\u0026Expires=1733038918\u0026Signature=Zxb8jTwGCWkbU-LYiRCdNKL8TR5g1~8Xtx0qWZAEWa9ogsFVuNmlvMLiuezCPHRUK59lrxvXG1lZau65bA3FeV6XJEjDNlGe7dX4-d56H90Q8GH9FAAmZm~xxJVc2Ir91LcghZpNP~W1zZLxByVlOgDQthODcCUmrbHvbjZeoJrSdRygowP0lGOD6SGBiw96ERNEIc2wlnKzNHWwzbVT3nATj9Uyd-BNcnQSj6Er6oUUplpjEXpuTri3TX1G7fOags9-~Ew7rhLvDqCgReK3kBpicKNQ-3z83ZmaWA5Jj~xWmst5TKCyJJ8L5iqIqRAc69G3jkxTGSlrBAbq9pgP2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":69637,"name":"Infection Control","url":"https://www.academia.edu/Documents/in/Infection_Control"},{"id":116078,"name":"Staphylococcus aureus","url":"https://www.academia.edu/Documents/in/Staphylococcus_aureus"},{"id":1381991,"name":"Methicillin Resistant Staphylococcus Aureus","url":"https://www.academia.edu/Documents/in/Methicillin_Resistant_Staphylococcus_Aureus"},{"id":2494432,"name":"Carriage","url":"https://www.academia.edu/Documents/in/Carriage"},{"id":3763015,"name":"Mupirocin 2","url":"https://www.academia.edu/Documents/in/Mupirocin_2"}],"urls":[{"id":45080955,"url":"https://doi.org/10.1186/s13756-015-0096-x"}]}, dispatcherData: dispatcherData }); 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Their claimed origin was India (n=11), DR Congo (n=5), France (n=4), Kenya (n=1), China (n=1), Germany(n=1), and Switzerland (n=1). The specimens were checked for falsifications following the WHO checklist. Content identity and amount of antibiotics in the specimens was investigated by Ultra High Performance Liquid Chromatography coupled with tandem mass spectrophotometry (UHPLC-MS/MS) and diode array detection (UHPLC-DAD). Nine of the 24 samples fulfilled the WHO criteria of counterfeit drugs, but all samples contained the active ingredients as claimed on the packages. We found under dosage of 90% and less in 3 of the 15 amoxicillin samples and in none of the 9 combined specimens. Amoxicillin over dosage (defined as 110% or more of indicated content) was found in 3 of the amoxicillin and in 1 of the combined specimens. Clavulanic acid was underdosed in none but overdosed in 5 of the 9 combined specimens. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601163"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601163/_The_infective_diseases_clinic_"><img alt="Research paper thumbnail of [The infective diseases clinic]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601163/_The_infective_diseases_clinic_">[The infective diseases clinic]</a></div><div class="wp-workCard_item"><span>Revue médicale de Bruxelles</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. Its main activity consists in taking care of patients with infectious complications in various hospital departments. Its main scientific contributions concern the evaluation of new treatments, pharmacokinetics of antimicrobial agents and physiopathology of sepsis. The evaluation of the impact of infectious diseases on the appropriateness of antimicrobial therapy and the control of infection is a major contribution of the clinic. Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601163"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601163"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601163; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601163]").text(description); $(".js-view-count[data-work-id=124601163]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601163; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601163']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601163, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601163]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601163,"title":"[The infective diseases clinic]","translated_title":"","metadata":{"abstract":"The Clinic of Infectious Diseases was created at Erasme Hospital in 1980. 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Several works concern the study of the immune response in case of infection due to an intracellular pathogen and in response to vaccination.","internal_url":"https://www.academia.edu/124601163/_The_infective_diseases_clinic_","translated_internal_url":"","created_at":"2024-10-10T05:08:13.310-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_The_infective_diseases_clinic_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":13734,"name":"Communicable Diseases","url":"https://www.academia.edu/Documents/in/Communicable_Diseases"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":125076,"name":"Sepsis","url":"https://www.academia.edu/Documents/in/Sepsis"},{"id":179934,"name":"Vaccination","url":"https://www.academia.edu/Documents/in/Vaccination"},{"id":220036,"name":"Antimicrobial","url":"https://www.academia.edu/Documents/in/Antimicrobial"},{"id":568312,"name":"Intensive Care Medicine","url":"https://www.academia.edu/Documents/in/Intensive_Care_Medicine"},{"id":871724,"name":"University Hospitals","url":"https://www.academia.edu/Documents/in/University_Hospitals"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601162"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/124601162/_The_hospital_epidemiology_and_hygiene_unit_"><img alt="Research paper thumbnail of [The hospital epidemiology and hygiene unit]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601162/_The_hospital_epidemiology_and_hygiene_unit_">[The hospital epidemiology and hygiene unit]</a></div><div class="wp-workCard_item"><span>Revue médicale de Bruxelles</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and controlling epidemics. In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601162"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601162"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601162; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601162]").text(description); $(".js-view-count[data-work-id=124601162]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601162; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601162']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601162, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=124601162]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601162,"title":"[The hospital epidemiology and hygiene unit]","translated_title":"","metadata":{"abstract":"The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and controlling epidemics. In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Revue médicale de Bruxelles"},"translated_abstract":"The hospital Epidemiology and Infection Control Unit aims at preventing nosocomial infections and controlling epidemics. In this field, several researches have contributed to improve the knowledge of infections secondary to biliary endoscopy, of epidemics of nosocomial Legionella and multiresistant gram negative and Staphylococcus aureus infections. Studies about the rational use of antibiotics have contributed to a better control of the transmission of multiresistant pathogens.","internal_url":"https://www.academia.edu/124601162/_The_hospital_epidemiology_and_hygiene_unit_","translated_internal_url":"","created_at":"2024-10-10T05:08:13.157-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_The_hospital_epidemiology_and_hygiene_unit_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[],"research_interests":[{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium"},{"id":66744,"name":"Biomedical Research","url":"https://www.academia.edu/Documents/in/Biomedical_Research"},{"id":69637,"name":"Infection Control","url":"https://www.academia.edu/Documents/in/Infection_Control"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":201203,"name":"Hygiene","url":"https://www.academia.edu/Documents/in/Hygiene"},{"id":251655,"name":"Antibiotics","url":"https://www.academia.edu/Documents/in/Antibiotics"},{"id":568312,"name":"Intensive Care Medicine","url":"https://www.academia.edu/Documents/in/Intensive_Care_Medicine"},{"id":871724,"name":"University Hospitals","url":"https://www.academia.edu/Documents/in/University_Hospitals"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601161"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study"><img alt="Research paper thumbnail of Human herpesvirus-6 infection after lung and heart-lung transplantation: a prospective longitudinal study" class="work-thumbnail" src="https://attachments.academia-assets.com/118797139/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study">Human herpesvirus-6 infection after lung and heart-lung transplantation: a prospective longitudinal study</a></div><div class="wp-workCard_item"><span>Transplantation</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="1c78567a3b6ecb1e6256131c1caf277d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797139,"asset_id":124601161,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797139/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601161"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601161"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601161; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601161]").text(description); $(".js-view-count[data-work-id=124601161]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601161; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601161']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601161, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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Although human herpesvirus (HHV)-6 is now recognized as a frequent pathogen after transplantation, the real impact of this infection in patients undergoing transplantation remains unclear. Methods. During 27 months, 30 consecutive heartlung-and lung-transplant recipients were included on the day of transplantation and prospectively followed during 100 days for HHV-6 infection. Results. HHV-6 infection occurred in 20 (66%) patients after a median delay of 18 days after transplantation. The virus was detected by polymerase chain reaction or culture, or both, in 15.7 % of blood specimens, in 14.5% of bronchoalveolar lavage fluids, and in many organs at postmortem examination; it was found by culture in eight patients. No clinical manifestations could clearly be associated with HHV-6 alone. However, patients with HHV-6 infection had a higher mortality rate than patients without HHV-6 infection (7 of 20 vs. 0 of 10; P‫,)40.0؍‬ and all the deceased patients died during periods of HHV-6 infection. We did not observe higher incidence of infectious or graft-rejection episodes in HHV-6-positive patients. However, eight of nine viral or fungal infections occurred during HHV-6 infection and three were directly responsible for death. Conclusion. Although frequently detected after transplantation, HHV-6 was not associated with any specific clinical manifestation. The higher mortality rate observed in patients with HHV-6 infection was not related to a higher incidence of bacterial infections or graft rejection but might be associated with more viral and fungal infections.","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Transplantation","grobid_abstract_attachment_id":118797139},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601161/Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study","translated_internal_url":"","created_at":"2024-10-10T05:08:12.889-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797139,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797139/thumbnails/1.jpg","file_name":"01.tp.0000058809.42027.6620241010-1-oth6ub.pdf","download_url":"https://www.academia.edu/attachments/118797139/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Human_herpesvirus_6_infection_after_lung.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797139/01.tp.0000058809.42027.6620241010-1-oth6ub-libre.pdf?1728564882=\u0026response-content-disposition=attachment%3B+filename%3DHuman_herpesvirus_6_infection_after_lung.pdf\u0026Expires=1733038918\u0026Signature=EWAC27fnuIwCxXwfk~z3s7-LeeLnjm4O7oU7wUORhUxwUmOOZprhXSVDKMYsV~SP8TmkWlzkOKHZApu42MbFXW4WEFQmU-VfC0J~m8tuxZd6XxTYb2h9c1UOzxubel0CAFjcG9-3xqYAQFdLppd3W-~gOFWIYgaINedoa2ODicrtgr3KH-s8eujr6TMAcwlhTLMPFng~37roEJ3K8kfK7d5Js8z6oCSoE7nnawkTaO63p6aKN18E6n~HyJyHMYj8Bau0R7p4NRy2P-D7wnu6WOwLVfHCdOdAcSqSj51yG2K6xh4bLA7mI9GVGldnsR-U9wdBNpp5QJ4rxO4HogAfLg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Human_herpesvirus_6_infection_after_lung_and_heart_lung_transplantation_a_prospective_longitudinal_study","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601160"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient"><img alt="Research paper thumbnail of Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient" class="work-thumbnail" src="https://attachments.academia-assets.com/118797135/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient">Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient</a></div><div class="wp-workCard_item"><span>Transplantation</span><span>, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="fcb2eb6934ad572cfa564064954e4fca" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797135,"asset_id":124601160,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601160"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601160"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601160; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601160]").text(description); $(".js-view-count[data-work-id=124601160]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId 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_.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "fcb2eb6934ad572cfa564064954e4fca" } } $('.js-work-strip[data-work-id=124601160]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601160,"title":"Fatal Primary Infection Due to Human Herpesvirus 6 Variant a in a Renal Transplant Recipient","translated_title":"","metadata":{"publisher":"Ovid Technologies (Wolters Kluwer Health)","grobid_abstract":"We describe a fatal primary human herpesvirus 6 (HHV-6) variant A infection in a kidney transplanted adult woman. On day 20 post transplantation (TX), after rejection therapy, the patient presented an acute hemophagocytic syndrome with hepatitis and central nervous system involvement. HHV-6 IgG and IgM antibodies seroconversion was demonstrated. HHV-6 variant A was the sole pathogen detected by nested PCR and/or culture in blood, bone marrow aspiration, liver biopsy, cerebrospinal fluid and bronchoalveolar lavage. The graft was HHV-6 seropositive and the patient was not transfused before day 28 post TX, suggesting that the virus was transmitted by the graft. Despite immunoglobulins, ganciclovir and foscarnet therapy, the HHV-6 infection progressed and led to severe aplasia. The patient developed Aspergillus fumigatus pneumonia and died from fulminant candidemia. This case demonstrated for the first time that HHV-6 variant A primary infection can cause lifethreatening disseminated infection in immunosuppressed patients.","publication_date":{"day":null,"month":null,"year":2001,"errors":{}},"publication_name":"Transplantation","grobid_abstract_attachment_id":118797135},"translated_abstract":null,"internal_url":"https://www.academia.edu/124601160/Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient","translated_internal_url":"","created_at":"2024-10-10T05:08:12.459-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":35639169,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":118797135,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797135/thumbnails/1.jpg","file_name":"00007890-200101270-0002120241010-1-ohz7gj.pdf","download_url":"https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Fatal_Primary_Infection_Due_to_Human_Her.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797135/00007890-200101270-0002120241010-1-ohz7gj-libre.pdf?1728564884=\u0026response-content-disposition=attachment%3B+filename%3DFatal_Primary_Infection_Due_to_Human_Her.pdf\u0026Expires=1733038918\u0026Signature=LCVXzVDcAhbepo2uloQT1yM9cRJAGfgvi3ux00P8Lkf2nPU1CyFVmwPA3O9HAX8OSEofmuZB9AsMKe7LFX33ww8B-2DcpZcMXb70S~lxXwvHcRlL4d1SABYtFyD~Im0uN04LFxWLfZJTR~qLjni6M5dvXVeRd1uDH~RizfhQjasXyIwjqs~WC5VzAwQL2UIfxfoL4jsgtm~6UflMDsEXpc9~qv8iQODGkOrav1IzPJeiVQeRKv62~sKFYWiU36mKeb91HtiECZRQAGyCLD8R7dOK-ZLTcbU8wahxWx1-fC6V5ZLbyURocXu-8kiPjt47Z9zILwNYRHLM9WnvCdDUkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Fatal_Primary_Infection_Due_to_Human_Herpesvirus_6_Variant_a_in_a_Renal_Transplant_Recipient","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":35639169,"first_name":"Baudouin","middle_initials":null,"last_name":"Byl","page_name":"BaudouinByl","domain_name":"independent","created_at":"2015-10-04T12:38:16.948-07:00","display_name":"Baudouin Byl","url":"https://independent.academia.edu/BaudouinByl"},"attachments":[{"id":118797135,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/118797135/thumbnails/1.jpg","file_name":"00007890-200101270-0002120241010-1-ohz7gj.pdf","download_url":"https://www.academia.edu/attachments/118797135/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Fatal_Primary_Infection_Due_to_Human_Her.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/118797135/00007890-200101270-0002120241010-1-ohz7gj-libre.pdf?1728564884=\u0026response-content-disposition=attachment%3B+filename%3DFatal_Primary_Infection_Due_to_Human_Her.pdf\u0026Expires=1733038918\u0026Signature=LCVXzVDcAhbepo2uloQT1yM9cRJAGfgvi3ux00P8Lkf2nPU1CyFVmwPA3O9HAX8OSEofmuZB9AsMKe7LFX33ww8B-2DcpZcMXb70S~lxXwvHcRlL4d1SABYtFyD~Im0uN04LFxWLfZJTR~qLjni6M5dvXVeRd1uDH~RizfhQjasXyIwjqs~WC5VzAwQL2UIfxfoL4jsgtm~6UflMDsEXpc9~qv8iQODGkOrav1IzPJeiVQeRKv62~sKFYWiU36mKeb91HtiECZRQAGyCLD8R7dOK-ZLTcbU8wahxWx1-fC6V5ZLbyURocXu-8kiPjt47Z9zILwNYRHLM9WnvCdDUkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":9003,"name":"Kidney transplantation","url":"https://www.academia.edu/Documents/in/Kidney_transplantation"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":51530,"name":"Transplantation","url":"https://www.academia.edu/Documents/in/Transplantation"},{"id":385972,"name":"Immunocompromised host","url":"https://www.academia.edu/Documents/in/Immunocompromised_host"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"},{"id":577933,"name":"Genetic variation","url":"https://www.academia.edu/Documents/in/Genetic_variation"},{"id":1495798,"name":"Fulminant","url":"https://www.academia.edu/Documents/in/Fulminant"},{"id":2056374,"name":"Seroconversion","url":"https://www.academia.edu/Documents/in/Seroconversion"},{"id":2422514,"name":"Foscarnet","url":"https://www.academia.edu/Documents/in/Foscarnet"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"},{"id":4055611,"name":"Fatal outcome","url":"https://www.academia.edu/Documents/in/Fatal_outcome"}],"urls":[{"id":45080953,"url":"http://journals.lww.com/00007890-200101270-00021"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="124601159"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/124601159/Outbreak_of_hospital_adapted_clonal_complex_17_vancomycin_resistant_Enterococcus_faecium_strain_in_a_haematology_unit_role_of_rapid_typing_for_early_control"><img alt="Research paper thumbnail of Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control" class="work-thumbnail" src="https://attachments.academia-assets.com/118797141/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/124601159/Outbreak_of_hospital_adapted_clonal_complex_17_vancomycin_resistant_Enterococcus_faecium_strain_in_a_haematology_unit_role_of_rapid_typing_for_early_control">Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control</a></div><div class="wp-workCard_item"><span>Journal of Antimicrobial Chemotherapy</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a366e82208cefc5474d062e69f07070f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":118797141,"asset_id":124601159,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/118797141/download_file?st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&st=MTczMzAzNTMxOCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="124601159"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="124601159"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 124601159; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=124601159]").text(description); $(".js-view-count[data-work-id=124601159]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 124601159; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='124601159']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 124601159, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "a366e82208cefc5474d062e69f07070f" } } $('.js-work-strip[data-work-id=124601159]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":124601159,"title":"Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"To describe the investigation and molecular characterization of a vancomycin-resistant Enterococcus faecium (VREF) strain responsible for a nosocomial outbreak in the haematology unit of a tertiary-care university hospital. Patients and methods: Two patients admitted to the haematology unit developed infection/colonization with VREF over a 3 month period when compared with none in the 2 previous years. On the basis of the identification of a clonal link between these two strains, weekly rectal screening was implemented for all patients in the haematology unit and contact precautions were extended to VREF carriers. In the following 6 month period, 11 patients colonized with VREF were detected. No further case was detected in the following 1 year period. Results: VREF isolates from the haematology unit carried the vanA gene and were multiresistant to antimicrobial agents, including high-level resistance to vancomycin, teicoplanin and ampicillin. This resistance profile restricted the choice of antimicrobial therapy to linezolid or investigational drugs such as tigecycline. Molecular analysis showed that 11 of 13 (85%) VREF isolates belonged to pandemic clonal complex-17 carrying the esp and hyl virulence genes. Conclusions: Rapid typing and infection control measures, including early reinforcement of barrier precautions combined with weekly rectal surveillance cultures, were followed by control of nosocomial spread of this VREF clone.","publication_date":{"day":null,"month":null,"year":2007,"errors":{}},"publication_name":"Journal of Antimicrobial 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chemotherapy","url":"https://www.academia.edu/Documents/in/Antimicrobial_chemotherapy"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype"},{"id":372410,"name":"Genotype","url":"https://www.academia.edu/Documents/in/Genotype"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces"},{"id":537769,"name":"Enterococcus faecium","url":"https://www.academia.edu/Documents/in/Enterococcus_faecium"},{"id":561014,"name":"Microbial Sensitivity Tests","url":"https://www.academia.edu/Documents/in/Microbial_Sensitivity_Tests"},{"id":588133,"name":"Linezolid","url":"https://www.academia.edu/Documents/in/Linezolid"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"},{"id":3854113,"name":"Cross Infection","url":"https://www.academia.edu/Documents/in/Cross_Infection"},{"id":3910486,"name":"Clonal 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data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/124601158/Is_Compliance_with_Hand_Disinfection_in_the_Intensive_Care_Unit_Related_to_Work_Experience">Is Compliance with Hand Disinfection in the Intensive Care Unit Related to Work Experience?</a></div><div class="wp-workCard_item"><span>Infection Control & Hospital Epidemiology</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The performance of hand disinfection by staff in a 31-bed department of intensive care was monito...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The performance of hand disinfection by staff in a 31-bed department of intensive care was monitored. During 32 hours of observation, 727 opportunities for hand disinfection were observed, and the compliance rate was 27.9%. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="122588593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/122588593/Impact_de_la_pand%C3%A9mie_A_H1N1_v2009_sur_le_fonctionnement_d_un_h%C3%B4pital_aigu_Bruxelles_Belgique"><img alt="Research paper thumbnail of Impact de la pandémie A(H1N1)v2009 sur le fonctionnement d’un hôpital aigu, Bruxelles, Belgique" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/122588593/Impact_de_la_pand%C3%A9mie_A_H1N1_v2009_sur_le_fonctionnement_d_un_h%C3%B4pital_aigu_Bruxelles_Belgique">Impact de la pandémie A(H1N1)v2009 sur le fonctionnement d’un hôpital aigu, Bruxelles, Belgique</a></div><div class="wp-workCard_item"><span>Revue D Epidemiologie Et De Sante Publique</span><span>, Sep 1, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="122588593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="122588593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 122588593; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="116422115"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/116422115/Ciprofloxacin_vs_Comparative_Antibiotics_in_LRTI"><img alt="Research paper thumbnail of Ciprofloxacin vs Comparative Antibiotics in LRTI" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/116422115/Ciprofloxacin_vs_Comparative_Antibiotics_in_LRTI">Ciprofloxacin vs Comparative Antibiotics in LRTI</a></div><div class="wp-workCard_item"><span>Drugs</span><span>, 1993</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In view of the excellent antimicrobial activity of ciprofloxacin against most respiratory pathoge...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In view of the excellent antimicrobial activity of ciprofloxacin against most respiratory pathogens and its good penetration into respiratory tissues and fluids, this drug has been extensively used for the treatment of lower respiratory tract infections (LRTI). However, the number of patients in most of the comparative trials was too small to enable a significant difference in efficacy between ciprofloxacin and the comparative drugs to be detected. 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