Breast Cancer - Cancer Science

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It is the most common cancer diagnosed in women and can also occur in men. Early detection and advanced treatment options have significantly improved the survival rates for breast cancer patients.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-risk-factors" title="What are the Risk Factors?"><h3>What are the Risk Factors?</h3></a>Several <a href="https://cancerscience.net/about/index/risk-factors" title="risk factors" target="_blank">risk factors</a> can increase the likelihood of developing breast cancer. These include:</div><div> <a href="https://cancerscience.net/about/index/age" title="Age" target="_blank">Age</a>: The risk increases as you get older.<br> <a href="https://cancerscience.net/about/index/genetics" title="Genetics" target="_blank">Genetics</a>: Family history and inherited gene mutations, such as BRCA1 and BRCA2.<br> <a href="https://cancerscience.net/about/index/hormones" title="Hormones" target="_blank">Hormones</a>: Prolonged exposure to estrogen, such as early menstruation or late menopause.<br> <a href="https://cancerscience.net/about/index/lifestyle-factors" title="Lifestyle factors" target="_blank">Lifestyle factors</a>: Obesity, alcohol consumption, and lack of physical activity.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-symptoms" title="What are the Symptoms?"><h3>What are the Symptoms?</h3></a>Common <a href="https://cancerscience.net/about/index/symptoms" title="symptoms" target="_blank">symptoms</a> of breast cancer include:</div><div> A lump or thickening in the breast or underarm area.<br> Changes in the size, shape, or appearance of the breast.<br> Dimpling or puckering of the skin.<br> Inverted nipple or nipple discharge.</div><div><a href="https://cancerscience.net/knowledgebase/how-is-breast-cancer-diagnosed" title="How is Breast Cancer Diagnosed?"><h3>How is Breast Cancer Diagnosed?</h3></a>Diagnosis typically involves a combination of <a href="https://cancerscience.net/about/index/screening" title="screening" target="_blank">screening</a> methods and diagnostic tests:</div><div> <a href="https://cancerscience.net/about/index/mammography" title="Mammography" target="_blank">Mammography</a>: An X-ray of the breast.<br> <a href="https://cancerscience.net/about/index/ultrasound" title="Ultrasound" target="_blank">Ultrasound</a>: Uses sound waves to produce images of structures within the breast.<br> <a href="https://cancerscience.net/about/index/biopsy" title="Biopsy" target="_blank">Biopsy</a>: Removal of a sample of breast tissue for laboratory testing.<br> <a href="https://cancerscience.net/about/index/magnetic-resonance-imaging-(mri)" title="Magnetic Resonance Imaging (MRI)" target="_blank">Magnetic Resonance Imaging (MRI)</a>: Uses magnets and radio waves to create detailed images.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-treatment-options" title="What are the Treatment Options?"><h3>What are the Treatment Options?</h3></a>Treatment for breast cancer depends on the stage and type of cancer. Common <a href="https://cancerscience.net/about/index/treatment-options" title="treatment options" target="_blank">treatment options</a> include:</div><div> <a href="https://cancerscience.net/about/index/surgery" title="Surgery" target="_blank">Surgery</a>: Lumpectomy or mastectomy to remove the tumor.<br> <a href="https://cancerscience.net/about/index/radiation-therapy" title="Radiation therapy" target="_blank">Radiation therapy</a>: Uses high-energy rays to target and kill cancer cells.<br> <a href="https://cancerscience.net/about/index/chemotherapy" title="Chemotherapy" target="_blank">Chemotherapy</a>: Uses drugs to kill cancer cells or stop them from growing.<br> <a href="https://cancerscience.net/about/index/hormone-therapy" title="Hormone therapy" target="_blank">Hormone therapy</a>: Blocks hormones that fuel certain types of breast cancer.<br> <a href="https://cancerscience.net/about/index/targeted-therapy" title="Targeted therapy" target="_blank">Targeted therapy</a>: Focuses on specific molecules involved in cancer growth and spread.</div><div><a href="https://cancerscience.net/knowledgebase/can-breast-cancer-be-prevented" title="Can Breast Cancer be Prevented?"><h3>Can Breast Cancer be Prevented?</h3></a>While there is no sure way to prevent <a href="https://cancerscience.net/about/index/breast-cancer" title="breast cancer" target="_blank">breast cancer</a>, certain lifestyle changes can reduce the risk:</div><div> Maintain a healthy weight.<br> Stay physically active.<br> Limit alcohol consumption.<br> Consider the risks of hormone replacement therapy.<br> Regular screening and self-exams for early detection.</div><div><a href="https://cancerscience.net/knowledgebase/what-is-the-prognosis" title="What is the Prognosis?"><h3>What is the Prognosis?</h3></a>The <a href="https://cancerscience.net/about/index/prognosis" title="prognosis" target="_blank">prognosis</a> for breast cancer depends on several factors, including the stage at diagnosis, the type of cancer, and the patient's overall health. Early-stage breast cancer has a higher survival rate, and many patients live long, healthy lives after treatment.</div><div><a href="https://cancerscience.net/knowledgebase/what-support-is-available" title="What Support is Available?"><h3>What Support is Available?</h3></a>Various <a href="https://cancerscience.net/about/index/support-services" title="support services" target="_blank">support services</a> are available for those affected by breast cancer, including:</div><div> Support groups and counseling.<br> Educational resources and patient advocacy organizations.<br> Financial assistance programs.<br> Rehabilitation and survivorship programs.</div></div> </div> <div id="recent_papers"> <br><hr /><br><h2 class="heading1">Relevant Publications</h2> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945908" target='_blank' title="[Pharmacological properties and clinical development overview of pertuzumab (genetical recombination), trastuzumab (genetical recombination) and vorhyaluronidase alfa (genetical recombination) (PHESGO combination for 鈥峴ubcutaneous injection MA, IN)].">[Pharmacological properties and clinical development overview of pertuzumab (genetical recombination), trastuzumab (genetical recombination) and vorhyaluronidase alfa (genetical recombination) (PHESGO combination for 鈥峴ubcutaneous injection MA, IN)].</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946836" target='_blank' title="Systemic oncological therapy in breast cancer patients on dialysis.">Systemic oncological therapy in breast cancer patients on dialysis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947662" target='_blank' title="Niraparib Maintenance Therapy for Brain Metastasis in Ovarian Endometrioid Adenocarcinoma With Peritoneal Carcinomatosis: A Comprehensive Case Study and Literature Review.">Niraparib Maintenance Therapy for Brain Metastasis in Ovarian Endometrioid Adenocarcinoma With Peritoneal Carcinomatosis: A Comprehensive Case Study and Literature Review.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38948022" target='_blank' title="Trametinib boosts palbociclib\'s efficacy in breast cancer via autophagy inhibition.">Trametinib boosts palbociclib\'s efficacy in breast cancer via autophagy inhibition.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38917957" target='_blank' title="Injectable nano-in situ-thermosensitive-hydrogels based on halofuginone and silver for postoperative treatment against triple-negative breast cancer.">Injectable nano-in situ-thermosensitive-hydrogels based on halofuginone and silver for postoperative treatment against triple-negative breast cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945330" target='_blank' title="Tetrastigma hemsleyanum polysaccharide combined with doxorubicin promote ferroptosis and immune function in triple-negative breast cancer.">Tetrastigma hemsleyanum polysaccharide combined with doxorubicin promote ferroptosis and immune function in triple-negative breast cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946287" target='_blank' title="Changes in experienced quality of oncological cancer care during the COVID-19 pandemic based on patient reported outcomes - a cross-sectional study.">Changes in experienced quality of oncological cancer care during the COVID-19 pandemic based on patient reported outcomes - a cross-sectional study.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946795" target='_blank' title="Retraction: Extracellular vesicles carry lncRNA SNHG16 to promote metastasis of breast cancer cells via the miR-892b/PPAPDC1A axis.">Retraction: Extracellular vesicles carry lncRNA SNHG16 to promote metastasis of breast cancer cells via the miR-892b/PPAPDC1A axis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947634" target='_blank' title="Role of Psychosomatic Medicine in Complex Medical Cases: A Case Study of a Patient With Breast Cancer Who Refused Mastectomy.">Role of Psychosomatic Medicine in Complex Medical Cases: A Case Study of a Patient With Breast Cancer Who Refused Mastectomy.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38942092" target='_blank' title="G protein pathway suppressor 2 suppresses aerobic glycolysis through RACK1-mediated HIF-1伪 degradation in breast cancer.">G protein pathway suppressor 2 suppresses aerobic glycolysis through RACK1-mediated HIF-1伪 degradation in breast cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944408" target='_blank' title="A critical appraisal of the role of 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candidates.">Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947033" target='_blank' title="The Gene Expression Landscape of Disease Genes.">The Gene Expression Landscape of Disease Genes.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947418" target='_blank' title="Circulating cell-free (cf)DNA analysis: Current technologies and applications in gynecologic cancer.">Circulating cell-free (cf)DNA analysis: Current technologies and applications in gynecologic cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945204" target='_blank' title="Electroacupuncture Facilitates Vascular Normalization by Inhibiting Glyoxalase1 in Endothelial Cells to Attenuate Glycolysis and Angiogenesis in Triple-Negative Breast Cancer.">Electroacupuncture Facilitates Vascular Normalization by Inhibiting Glyoxalase1 in Endothelial Cells to Attenuate Glycolysis and Angiogenesis in Triple-Negative Breast Cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947755" target='_blank' title="Establishment of a humanized mouse model using steady-state peripheral blood-derived hematopoietic stem and progenitor cells facilitates screening of cancer-targeted T-cell repertoires.">Establishment of a humanized mouse model using steady-state peripheral blood-derived hematopoietic stem and progenitor cells facilitates 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