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color: #fff; } .editor-header1 h3 { margin-top: 5px; } .editor-header1 p { margin: 20px 0px 0px 0px; font-size:25px; } .editor-header1 h1 { margin: 10px; } </style> <div class="container-fluid editor-view"> <div class="row editor-header"> <h1>Dr. Jatin Machhi</h1> <h3>Journal of Biomedical Research and Reviews</h3> <h5>Department of Pharmacology and Experimental Neuroscience</h5> <img src="https://www.innovationinfo.org/editorialboardmembers/Jatinkumar.jpg"> </div> </div> <div class="container content-top"> <div class="row"> <div class="col-md-12"> <ul class="nav nav-pills nav-justified editor-tabs responsive"> <li class="active"><a data-toggle="tab" href="#home">About</a></li> <li><a data-toggle="tab" href="#menu1">Publications</a></li> <li><a data-toggle="tab" href="#menu2">Certificate</a></li> <li><a data-toggle="tab" href="#menu3">Video</a></li> </ul> <div class="tab-content" style=" text-align: justify;"> <div id="home" class="tab-pane fade in active"> <div class="nav_inn reg-forms1"> <div class="row"> <div class="col-md-6"> <p><strong>Name:</strong> Dr. Jatin Machhi </p> <p><strong>Educational Qualification:</strong> Ph.D. </p> <p><strong>Designation:</strong> Instructor at University of Nebraska Medical Center, Omaha, USA </p> <p><strong>Department:</strong> Department of Pharmacology and Experimental Neuroscience </p> <p><strong>University:</strong> University of Nebraska Medical Center </p></center></div> </div>  <div class="row"><div class="col-md-12"> <p><strong>Email:</strong> jtnmachhi@gmail.com</p> <p><strong>Research Interests:</strong> Pharmacology, Immunology, Neuroscience</p> <p><strong>Biography:</strong> Dr. Machhi is an Instructor at the University of Nebraska Medical Center. He completed his education from the reputed institutes of the India include Bachelor of Pharmacy from the Sardar Pater University, Master of Pharmacy from the Gujarat Technological University and Ph.D. from the Maharaja Sayajirao University of Baroda. He also served as a postdoctoral research associate at the University of Nebraska Medical Center. Dr. Machhi is a highly experienced and dedicated professional with eight years of research experience in pharmacology, neuroimmunology and neurodegenerartive diseases including Alzheimer鈥檚 and Parkinson鈥檚 disease. Also experienced in studying HIV pathogenesis and antiretroviral drug biodistribution up to cellular level. Currently working on development of T cell immune therapies for the potential treatment of neurodegenerative diseases. Also developing next-generation mouse models of Alzheimer鈥檚 disease using CRISPR-Cas9 technology.</p> <p> <p><strong>Patent</strong></p> <p>Mange Ram Yadav, Mahesh Shidore, <strong>Jatin Machhi</strong>, Prashant Murumkar, Rajani Giridhar. 3-Benzazapine-2-one derivatives as 5-HT 2C receptor agonists and the process for their preparation.</p> <p>Indian Patent, Appl./959/MUM/2015</p> <p><strong>Served as reviewer in journals</strong></p> <ul> <li> <p>Journal of Neuroimmune Pharmacology (Springer)</p> </li> <li> <p>BMC Immunology (BMC)</p> </li> <li> <p>Translational Neurodegeneration (BMC)</p> </li> <li> <p>Journal of International Medical Research (Sage)</p> </li> <li> <p>Bioorgenic Chemistry (Elsevier)</p> </li> <li> <p>Americal Journal of Nanomaterials</p> </li> <li> <p>Journal of Neuroscience and Neurological Surgery</p> </li> <li> <p>Acta Scientific</p> </li> </ul> <p><strong>Editorial Board Member</strong></p> <ul> <li> <p>Journal of Neuroimmune Pharmacology (Editor-in-training, Springer)</p> </li> <li> <p>Acta Scientific Neurology</p> </li> <li> <p>Journal of Neuroscience and Neurological Surgery</p> </li> <li> <p>American Journal of Psychiatry and Neuroscience</p> </li> </ul> </p> </div></div>  </div> </div> <div id="menu1" class="tab-pane fade"> <div class="nav_inn reg-forms1"> <p> <ol> <li><strong>Jatin Machhi</strong> et al., (2021) Nanocarrier Vaccines for SARS-CoV-2. <em>Advanced Drug Delivery Reviews</em> (in press)</li> <li><strong>Jatin Machhi</strong> et al., (2021) A Role for Extracellular Vesicles in SARS-CoV-2 Therapeutics and Prevention. <em>Journal of Neuroimmune Pharmacology</em> (in press)</li> <li>Bhavesh Kevadiya, <strong>Jatin Machhi</strong> et al., (2020) Diagnostics for SARS-CoV-2 Infections. <em>Nature Materials</em> (in press).</li> <li>Bhavesh Kevadiya, <strong>Jatin Machhi</strong> et al., (2020) Pharmacotherapeutics of SARS-CoV-2 Infections. <em>Journal of Neuroimmune Pharmacology</em> (in press).</li> <li><strong>Jatin Machhi</strong> et al., (2020) The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections. <em>Journal of Neuroimmune Pharmacology</em> 21, 1-28.</li> <li><strong>Jatin Machhi</strong>, Bhavesh Kevadiya, Ijaz Khan Muhammad, et al., (2020) Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders. <em>Molecular Neurodegeneration </em>15 (1), 32.</li> <li>Insiya Z. Mukadam,<strong> Jatin Machhi, </strong>et al., (2020) Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking. <em>Biomaterials</em> 231, 119669.</li> <li>Aaron D. Schwab, Mackenzie J. Thurston,<strong> Jatin Machhi, </strong>et al., (2020) Immunotherapy for Parkinson's disease. <em>Neurobiology of Disease</em>, 137, 104760.</li> <li>Bhavesh D Kevadiya, Brendan Ottemann, Insiya Z Mukadam, Laura Castellanos, Kristen Sikora, James R Hilaire, <strong>Jatin Machhi</strong>, et al., (2020) Rod-shape theranostic nanoparticles facilitate antiretroviral drug biodistribution and activity in human immunodeficiency virus susceptible cells and tissues. <em>Theranostics</em> 10 (2), 630.</li> <li>R. L. Mosley, Yaman Lu, Katherine E. Olson,<strong> Jatin Machhi, </strong>et al., (2019) A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson’s Disease. <em>Frontiers in Cellular Neuroscience</em> 13, 421.</li> <li>Tomomi Kiyota,<strong> Jatin Machhi* </strong>et al., (2018) URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease. <em>Journal of neuroinflammation</em> 15 (1), 137 (*Shared first author).</li> <li>Tomomi Kiyota,<strong> Jatin Machhi </strong>et al., (2018) Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice. <em>Journal of neuroimmunology</em> 319, 80-92.</li> <li>Mayank K. Sharma,<strong> Jatin Machhi </strong>et al., (2018) New role of phenothiazine derivatives as peripherally acting CB1 receptor antagonizing anti-obesity agents. <em>Scientific reports</em> 8 (1), 1-18.</li> <li>Midhun B Thomas, Divya Prakash Gnanadhas, Prasanta K Dash,<strong> Jatin Machhi </strong>et al., (2018) Modulating cellular autophagy for controlled antiretroviral drug release<em>. Nanomedicine</em> 13 (17), 2139-2154.</li> <li><strong>Jatin Machhi</strong> et al., (2017) Synthesis and biological evaluation of novel multi-target-directed benzazepines against excitotoxicity. <em>Molecular neurobiology</em> 54 (9), 6697-6722.</li> <li>Ragitha Chruvattil, Shreya Banerjee, Sarmi Nath,<strong> Jatin Machhi </strong>et al., (2017) Dexamethasone alters the appetite regulation via induction of hypothalamic insulin resistance in rat brain. <em>Molecular neurobiology</em> 54 (9), 7483-7496.</li> <li><strong>Jatin Machhi </strong>et al., (2016) Neuroprotective Potential of Novel Multi-Targeted Isoalloxazine Derivatives in Rodent Models of Alzheimer’s Disease Through Activation of Canonical Wnt/β-Catenin Signalling Pathway. <em>Neurotoxicity research</em> 29 (4), 495-513.</li> <li>Mahesh Shidore,<strong> Jatin Machhi* </strong>et al., (2016) Benzylpiperidine-linked diarylthiazoles as potential anti-Alzheimer’s agents: synthesis and biological evaluation. <em>Journal of medicinal chemistry</em> 59 (12), 5823-5846 (*Shared first author).</li> <li>Neetesh Agrawal, <strong>Jatin Machhi </strong>et al., (2016) Exploration of 6,7-dimethoxyquinazoline derivatives as dual acting α1- and AT1-receptor antagonists: synthesis, evaluation, pharmacophore & 3D-QSAR modeling and receptor docking studies. <em>RSC advances</em> 6 (36), 30661-30682.</li> <li><strong>Jatin Machhi</strong> et al., (2015) D3 Antagonist and Antipsychotic Potential of Some Novel Benzazepines. <em>Journal of Pharmaceutical Sciences and Pharmacology</em> 2 (2), 123-133.</li> <li>Mahesh Shidore, <strong>Jatin Machhi</strong> et al., (2015) 3-Substituted 1-methyl-3-benzazepin-2-ones as 5-HT 2C receptor agonists. <em>RSC Advances</em> 5 (111), 91908-91921.</li> <li>Ashish M Kanhed, Anshuman Sinha, <strong>Jatin Machhi</strong> et al., (2015) Discovery of isoalloxazine derivatives as a new class of potential anti-Alzheimer agents and their synthesis. <em>Bioorganic chemistry</em> 61, 7-12.</li> <li><strong>Jatin Machhi</strong> and N. N. Shah, (2012) Study of antiatherosclerotic activity of polyherbal preparation using rat as an experimental animal model. <em>International Journal Of Pharmaceutical Sciences And Research</em> 3 (10), 4010.</li> </ol> </p> </div> </div> <div id="menu2" class="tab-pane fade"> <div class="nav_inn reg-forms1"> <div class='row row-sm-flex-center' style="width:50%;margin:auto"> <div class="col-xs-12 col-sm-6 col-md-6"> <center> </center> </div> <div class="col-xs-12 col-sm-6 col-md-6 marg"> <center><img src="https://www.innovationinfo.org/editorialboardmembers/Jatinkumar.jpg" class="" alt="Circular Image" style="height:25%;width:25%;border:1"> <div class="para"> <p><b>Serial no</b>:</p></div> <a href="https://www.innovationinfo.org/certificate/" download="" class="btn btn-success">Download Certificate</a> </center> </div> </div> </div> </div> <div id="menu3" class="tab-pane fade"> <div class="nav_inn"> <div class="embed-responsive embed-responsive-16by9"> <iframe class="embed-responsive-item" src="https://www.youtube.com/embed/?rel=0" allowfullscreen></iframe> </div> </div> </div> </div> </div> </div> </div>  <style> .hover-item1:hover { color:#8dc449 ; 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