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Gerhard, 1927-" /> </div> </form> <div class="bibSearchHistory"> </div> </div>  <div class="bibPager"> <div>Record 1 of 5 </div> <a href="/search~S1?/aVogel%2C+H.+Gerhard%2C+1927-/avogel+h+gerhard+++++1927/1%2C1%2C1%2CB/frameset&FF=avogel+gretchen&0%2C%2C0"><span class="button"><img src="/screens/ico_previous.gif" alt=""><span class="buttonText">Previous Record</span></span></a> <a href="/search~S1?/aVogel%2C+H.+Gerhard%2C+1927-/avogel+h+gerhard+++++1927/1%2C1%2C5%2CB/frameset&FF=avogel+h+gerhard+++++1927&2%2C%2C5"><span class="button"><span class="buttonText" id="buttonNextRecord">Next Record</span><img src="/screens/ico_next.gif" alt=""></span></a> </div> <div class="bibClear"></div> <div class="bibResourceSidebar">  <a href="/record=b2532254~S1"><span class="button buttonNav">&nbsp&nbspPermalink&nbsp&nbsp&nbsp&nbsp</span></a></div> <div class="bibDisplayJacket"> <img src="https://secure.syndetics.com/index.aspx?isbn=9783540898917/SC.gif&client=deaka&type=unbound" border="0" alt="Book Cover"><div class="bibMedia"> <img src="/screens/media_ebook.gif" alt="E-book"></div> </div> <div class="bibDisplayContentMain">  <script src="https://ajax.googleapis.com/ajax/libs/jquery/1.11.1/jquery.min.js" type="text/javascript"></script> <link href="https://maxcdn.bootstrapcdn.com/font-awesome/4.6.3/css/font-awesome.min.css" rel="stylesheet" integrity="sha384-T8Gy5hrqNKT+hzMclPo118YTQO6cYprQmhrYwIiQ/3axmI1hQomh7Ud2hPOy8SP1" crossorigin="anonymous"> <script src="https://www.stackmap.com/integration/deakin_webpac/StackMap.js" type="text/javascript"></script> <link rel="stylesheet" media="all" type="text/css" href="https://www.stackmap.com/integration/deakin_webpac/StackMap.css" />   <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibDetail"> <tr class="bibInfoEntry" ><td>  <table width="100%" cellspacing="3" cellpadding="0"> </table>  </td></tr> </table>  <h1 class="bibDisplayTitle">  <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibDetail"> <tr class="bibInfoEntry" ><td>  <table width="100%" cellspacing="3" cellpadding="0"> <tr> <td valign="top" width="20%" class="bibInfoLabel">Title</td> <td class="bibInfoData"> <strong>Drug discovery and evaluation : methods in clinical pharmacology / Hans Gerhard Vogel, Jochen Mass, Alexander Gebauer (Eds.)</strong></td></tr> </table>  </td></tr> </table>    <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibDetail"> <tr class="bibInfoEntry" ><td>  <table width="100%" cellspacing="3" cellpadding="0"> <tr> <td valign="top" width="20%" class="bibInfoLabel">Published</td> <td class="bibInfoData"> Berlin ; London : Springer, 2011</td></tr> </table>  </td></tr> </table>  <div class="testlinkeddocs"> </div> <div class="bibDisplayUrls"> <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibLinks"> <tr><th> Click on the following:</th></tr> <tr align="center"> <td > <a href="http://ezproxy.deakin.edu.au/login?url=https://link.springer.com/10.1007/978-3-540-89891-7" onclick="window.open('http://ezproxy.deakin.edu.au/login?url=https://link.springer.com/10.1007/978-3-540-89891-7'); return false;">Springer eBooks</a><br /> </td> </tr> <tr align="center"> <td > <a href="http://ezproxy.deakin.edu.au/login?url=https://link.springer.com/10.1007/978-3-540-89891-7" onclick="window.open('http://ezproxy.deakin.edu.au/login?url=https://link.springer.com/10.1007/978-3-540-89891-7'); return false;">Springer Biomedical and Life Sciences eBooks</a><br /> </td> </tr> </table> </div> <div class="bibDisplayItems"> <div class="bibDisplayItemsHeader"><h2>Copies</h2></div> <div class="bibDisplayItemsMain"> </div> </div> <div class="bibDisplayContentMore">  <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibDetail"> <tr class="bibInfoEntry" ><td>  <table width="100%" cellspacing="3" cellpadding="0"> <tr> <td valign="top" width="20%" class="bibInfoLabel">Description</td> <td class="bibInfoData"> 1 online resource</td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Contents</td> <td class="bibInfoData"> Section A. Introduction -- section B. Clinical pharmacokinetics -- section C. Human studies in clinical pharmacology -- section D. Regulations</td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Summary</td> <td class="bibInfoData"> Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume 鈥濻afety and Pharmacokinetic Assays". Only then are隆first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: 鈥濵ethods in Clinical Pharmacology."</td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Bibliography</td> <td class="bibInfoData"> Includes bibliographical references and index</td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Notes</td> <td class="bibInfoData"> Print version record</td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Subject</td> <td class="bibInfoData"> <a href="/search~S1?/dPharmacology%2C+Experimental./dpharmacology+experimental/-3,-1,0,B/browse">Pharmacology, Experimental.</a> </td></tr> <tr> <td></td> <td class="bibInfoData"> <a href="/search~S1?/dDrug+Discovery+--+methods/ddrug+discovery+methods/-3,-1,0,B/browse">Drug Discovery -- methods</a> </td></tr> <tr> <td></td> <td class="bibInfoData"> <a href="/search~S1?/dDrug+Evaluation+--+methods/ddrug+evaluation+methods/-3,-1,0,B/browse">Drug Evaluation -- methods</a> </td></tr> <tr> <td></td> <td class="bibInfoData"> <a href="/search~S1?/dPharmacology%2C+Experimental/dpharmacology+experimental/-3,-1,0,B/browse">Pharmacology, Experimental</a> </td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Form</td> <td class="bibInfoData"> <a href="/search~S1?/hElectronic+book/helectronic+book/-3,-1,0,B/browse">Electronic book</a> </td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">Author</td> <td class="bibInfoData"> <a href="/search~S1?/aVogel%2C+H.+Gerhard%2C+1927-/avogel+h+gerhard+++++1927/-3,-1,0,B/browse">Vogel, H. Gerhard, 1927-</a> </td></tr> <tr> <td></td> <td class="bibInfoData"> <a href="/search~S1?/aMass%2C+Jochen/amass+jochen/-3,-1,0,B/browse">Mass, Jochen</a> </td></tr> <tr> <td></td> <td class="bibInfoData"> <a href="/search~S1?/aGebauer%2C+Alexander/agebauer+alexander/-3,-1,0,B/browse">Gebauer, Alexander</a> </td></tr> <tr> <td valign="top" width="20%" class="bibInfoLabel">ISBN</td> <td class="bibInfoData"> 9783540898917</td></tr> <tr> <td></td> <td class="bibInfoData"> 3540898913</td></tr> </table>  </td></tr> </table>   <table width="100%" border="0" cellspacing="0" cellpadding="0" class="bibDetail"> <tr class="bibInfoEntry" ><td>  <table width="100%" cellspacing="3" cellpadding="0"> </table>  </td></tr> </table>  </div>         <div class="bibDisplayContentMore bibDisplayReviews"> <div class="bibDisplayPermLink actionButtonArea"> <a href="/record=b2532254~S1"><span class="button buttonNav">&nbsp&nbspPermalink&nbsp&nbsp&nbsp&nbsp</span></a></div> </div> </div>  <script src="https://unbound.syndetics.com/syndeticsunbound/connector/initiator.php?a_id=465&i_id=1182" type="text/javascript"></script>  </div> <div class="clear"></div> </div> <br />    </div> <div style="clear:both"></div> </div> <iframe src="https://www.deakin.edu.au/library/media/static/deakin-footer2" target="_top" style="width:100%;height: 648px;border: none;overflow: hidden;margin: 0;" scrolling="no" aria-label="Deakin footer" title="Deakin footer"></iframe>   </body> </html> <script> // replace generic title in head with item title if (jQuery("div.navigationRow form select option").length !== 0) { document.title = jQuery("div.navigationRow form select option").next().html().trim(); /*addMetaTag('og:title', document.title);*/ } else if (jQuery("tr td.bibInfoLabel:contains('Title')").length !== 0) { document.title = jQuery("tr td.bibInfoLabel:contains('Title')").next().children('strong').text().trim(); /*addMetaTag('og:title', document.title);*/ } </script>  <script type='text/javascript'> var meta = document.createElement('meta'); meta.setAttribute('name' , 'description'); meta.setAttribute('content', document.title + ' is a resource in the Deakin University Library collection'); document.head.appendChild(meta); </script> <script type='text/javascript'> var meta = document.createElement('meta'); meta.setAttribute('name', 'viewport'); meta.setAttribute('content','width=device-width, initial-scale=1.0'); document.head.appendChild(meta); </script>  <script type='text/javascript'> var link = document.createElement('link'); link.setAttribute('rel', 'alternate'); link.setAttribute('href', 'http:' + '//' + 'm.library.deakin.edu.au' + location.pathname); link.setAttribute ('media', 'only screen and (max-width: 640px)') document.head.appendChild(link); </script> <script type='text/javascript'> var link = document.createElement('link'); link.setAttribute('rel', 'canonical'); link.setAttribute('href', 'http:' + '//' + 'library.deakin.edu.au' + location.pathname); document.head.appendChild(link); </script>