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phytochemical constituents</title> <meta name="description" content="Search results for: phytochemical constituents"> <meta name="keywords" content="phytochemical constituents"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="phytochemical constituents"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 632</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: phytochemical constituents</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">542</span> A contribution to Phytochemical and Biological Studies of Ailanthus Alitssima Swingle Cultivated in Egypt</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Samy%20Elnoby">Ahmed Samy Elnoby</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ailanthus altissima native to Asia which belongs to the family Simaroubaceae was subjected to phytochemical screening and biological investigations. Phytochemical screening revealed the presence of carbohydrates, tannins, sterols, flavonoids and traces of saponins. In addition, quantitative determination of phenolics and flavonoid content were performed. The antimicrobial activity of methanolic extract of the leaves was determined against gram-positive, gram-negative bacteria in addition to fungi using a modified Kirby-Bauer disc diffusion method that was compared with standard discs ampicillin which acts as an antibacterial agent and amphotericin B which acts as an antifungal agent. A high potency was observed against gram-positive bacteria mainly staphylococcus aureus, gram-negative bacteria mainly Escherichia coli and showed no potency against fungi mainly Aspergillus flavus and candida albicans. On the other hand, the antioxidant activity of the extract was determined by 1, 1-diphenyl-2- diphenyl-2-picryl-hydrazil (DPPH). A very low potency was shown by using DPPH for the antioxidant effect so IC50 = 0 ug/ml, IC90 =0 ug /ml and remark gave 47.2 % at 100 ug/ml which is very weak. Cytotoxic activity was determined by using MTT assay (3-4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) against MCF7 (Human Caucasian breast adenocarcinoma) cell line. A moderate potency was shown by using MCF7 cell line for cytotoxic effect so LC50= 90.2 ug/ml, LC90=139.9 ug/ml and the remark gave 55.2% at 100 ug/ml which is of moderate activity so, Ailanthus altissima can be considered to be a promising antimicrobial agent from natural origin. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ailanthus%20altissima" title="Ailanthus altissima">Ailanthus altissima</a>, <a href="https://publications.waset.org/abstracts/search?q=TLC" title="TLC">TLC</a>, <a href="https://publications.waset.org/abstracts/search?q=HPLC" title="HPLC">HPLC</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-microbial%20activity" title="anti-microbial activity">anti-microbial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal%20activity" title="antifungal activity">antifungal activity</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title="antioxidant">antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=cytotoxic%20activity" title="cytotoxic activity">cytotoxic activity</a> </p> <a href="https://publications.waset.org/abstracts/140076/a-contribution-to-phytochemical-and-biological-studies-of-ailanthus-alitssima-swingle-cultivated-in-egypt" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140076.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">174</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">541</span> Antibacterial Activity of Libyan Seaweed Extracts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Salmin%20K.%20Alshalmani">Salmin K. Alshalmani</a>, <a href="https://publications.waset.org/abstracts/search?q=Nada%20H.%20Zobi"> Nada H. Zobi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ismaeel%20H.%20Bozakouk"> Ismaeel H. Bozakouk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Marine organisms are potentially prolific sources of highly bio active secondary metabolites that might represent useful leads in the development of new pharmaceutical agents. The Libyan marine biodiversity including macroalgae remains partially unexplored in term of their potential bio activities. The phytochemical analysis of the alcoholic extracts of some commonly occurring seaweed Cystoseira compressa, enteromorpha intestinals, corallina, and Ulva lactuca and their evaluated for antibacterial activity by well diffusion assay were studied. Four different solvents namely water, ethanol 99 %, methanol 99 %, and methylated spirit 95 % were used for extraction. The phytochemical analysis revealed the presence of carbohydrates, steroids, tannin & phenols, saponins, proteins, and glycosides. The extracts were subjected for study of antibacterial activity. The zone of inhibition ranged between 8 to 16 mm in aqueous extract and up to 16 mm in methanol extract. The maximum activity (16 mm) was recorded from methanol extract of Ulva lactuca against Staphylococcus aureus and, minimum activity (8mm) recorded by Cystoseira compressa against S. aureus. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=macroalgae" title="macroalgae">macroalgae</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemicals" title=" phytochemicals"> phytochemicals</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title=" antibacterial activity"> antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=methanolic%20extract" title=" methanolic extract"> methanolic extract</a> </p> <a href="https://publications.waset.org/abstracts/16585/antibacterial-activity-of-libyan-seaweed-extracts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16585.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">469</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">540</span> Extracting the Antioxidant Compounds of Medicinal Plant Limoniastrum guyonianum</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Assia%20Belfar">Assia Belfar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Hadjadj"> Mohamed Hadjadj</a>, <a href="https://publications.waset.org/abstracts/search?q=Messaouda%20Dakmouche"> Messaouda Dakmouche</a>, <a href="https://publications.waset.org/abstracts/search?q=Zineb%20Ghiaba"> Zineb Ghiaba</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahdi%20Belguidoum"> Mahdi Belguidoum</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: This study aims to phytochemical screening; Extracting the active compounds and estimate the effectiveness of antioxidant in Medicinal plants desert Limoniastrum guyonianum (Zeïta) from South Algeria. Methods: Total phenolic content and total flavonoid content using Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. The total antioxidant capacity was estimated by the following methods: DPPH (1.1-diphenyl-2-picrylhydrazyl radical) and reducing power assay. Results: Phytochemical screening of the plant part reveals the presence of phenols, saponins, flavonoids and tannins. While alkaloids and Terpenoids were absent. The Methanolic extract of L. guyonianum was extracted successively with ethyl acetate and butanol. Extraction of yield varied widely in the L. guyonianum ranging from (1.315 % to 4.218%). butanol fraction had the highest yield. The higher content of phenols was recorded in butanol fraction (311.81 ± 0.02mg GAE/g DW), the higher content of flavonoids was found in butanol fraction (9.58 ± 0.33mg QE/g DW). IC50 of inhibition of radical DPPH in ethyl acetate fraction was (0.05 ± 0.01µg/ml) Equal effectiveness with BHT, All extracts showed good activity of ferric reducing power, the higher power was in butanol fraction (16.16 ± 0.05mM). Conclusions: Demonstrated this study that the Methanolic extract of L. guyonianum contain a considerable quantity of phenolic compounds and possess a good antioxidant activity. It can be used as an easily accessible source of Natural Antioxidants and as a possible food supplement and in pharmaceutical industry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=flavonoid%20compound" title="flavonoid compound">flavonoid compound</a>, <a href="https://publications.waset.org/abstracts/search?q=l.%20guyonianum" title=" l. guyonianum"> l. guyonianum</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compounds" title=" phenolic compounds"> phenolic compounds</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening"> phytochemical screening</a> </p> <a href="https://publications.waset.org/abstracts/45913/extracting-the-antioxidant-compounds-of-medicinal-plant-limoniastrum-guyonianum" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45913.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">539</span> Development of selective human matrix metalloproteinases-9 (hMMP-9) inhibitors as potent diabetic wound healing agents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Geetakshi%20Arora">Geetakshi Arora</a>, <a href="https://publications.waset.org/abstracts/search?q=Danish%20Malhotra"> Danish Malhotra</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetic wounds are serious health issues and often fail to heal, leading to limb amputation that makes the life of the patient miserable. Delayed wound healing has been characterized by an increase in matrix metalloproteinase-9 (MMP-9). Thus research throughout the world has been going on to develop selective MMP-9 inhibitors for aiding diabetic wound healing. Bioactive constituents from natural sources always served as potential leads in drug development with high rates of success. Considering the need for novel selective MMP-9 inhibitors and the importance of natural bioactive compounds in drug development, we have screened a library of bioactive constituents from plant sources that were effective in diabetic wound healing on human MMP-9 (hMMP-9) using molecular docking studies. Screened constituents are ranked according to their dock score, ∆G value (binding affinity), and Ligand efficiency evaluated from FleXX docking and Hyde scoring modules available with drug designing platform LeadIT. Rhamnocitrin showed the highest correlation between dock score, ∆G value (binding affinity), and Ligand efficiency was further explored for binding interactions with hMMP-9. The overall study suggest that Rhamnocitrin is sufficiently decorated with both hydrophilic and hydrophobic substitutions that perfectly block hMMP-9 and act as a potential lead in the design and development of selective hMMP-9 inhibitors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MMP-9" title="MMP-9">MMP-9</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetic%20wound" title=" diabetic wound"> diabetic wound</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20docking" title=" molecular docking"> molecular docking</a>, <a href="https://publications.waset.org/abstracts/search?q=phytoconstituents" title=" phytoconstituents"> phytoconstituents</a> </p> <a href="https://publications.waset.org/abstracts/155307/development-of-selective-human-matrix-metalloproteinases-9-hmmp-9-inhibitors-as-potent-diabetic-wound-healing-agents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155307.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">538</span> Quality Control of Distinct Cements by IR Spectroscopy: First, insights into Perspectives and Opportunities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tobias%20Bader">Tobias Bader</a>, <a href="https://publications.waset.org/abstracts/search?q=Joerg%20Rickert"> Joerg Rickert</a> </p> <p class="card-text"><strong>Abstract:</strong></p> One key factor in achieving net zero emissions along the cement and concrete value chain in Europe by 2050 is the use of distinct constituents to produce improved and advanced cements. These cements will contain e.g. calcined clays, recycled concrete fines that are chemically similar as well as X-ray amorphous and therefore difficult to distinguish. This leads to enhanced requirements on the analytical methods for quality control regarding accuracy as well as reproducibility due to the more complex cement composition. With the methods currently provided for in the European standards, it will be a challenge to ensure reliable analyses of the composition of the cements. In an ongoing research project, infrared (IR) spectroscopy in combination with mathematical tools (chemometrics) is going to be evaluated as an additional analytical method with fast and low preparation effort for the characterization of silicate-based cement constituents. The resulting comprehensive database should facilitate determination of the composition of new cements. First results confirmed the applicability of near-infrared IR for the characterization of traditional silicate-based cement constituents (e.g. clinker, granulated blast furnace slag) and modern X-ray amorphous constituents (e.g. calcined clay, recycled concrete fines) as well as different sulfate species (e.g. gypsum, hemihydrate, anhydrite). A multivariant calibration model based on numerous calibration mixtures is in preparation. The final analytical concept to be developed will form the basis for establishing IR spectroscopy as a rapid analytical method for characterizing material flows of known and unknown inorganic substances according to their material properties online and offline. The underlying project was funded by the Federal Institute for Research on Building, Urban Affairs and Spatial Development on behalf of the Federal Ministry of Housing, Urban Development and Building with funds from the ‘Zukunft Bau’ research programme. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cement" title="cement">cement</a>, <a href="https://publications.waset.org/abstracts/search?q=infrared%20spectroscopy" title=" infrared spectroscopy"> infrared spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20control" title=" quality control"> quality control</a>, <a href="https://publications.waset.org/abstracts/search?q=X-ray%20amorphous" title=" X-ray amorphous"> X-ray amorphous</a> </p> <a href="https://publications.waset.org/abstracts/188878/quality-control-of-distinct-cements-by-ir-spectroscopy-first-insights-into-perspectives-and-opportunities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188878.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">41</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">537</span> Progressive Changes in Physico-Chemical Constituent of Rainwater: A Case Study at Oyoko, a Rural Community in Ghana</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20O.%20Yeboah">J. O. Yeboah</a>, <a href="https://publications.waset.org/abstracts/search?q=K%20Aboraa"> K Aboraa</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Kodom"> K. Kodom </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The chemical and physical characteristics of rainwater harvested from a typical rooftop were progressively studied. The samples of rainwater collected were analyzed for pH, major ion concentrations, TDS, turbidity, conductivity. All the physicochemical constituents fell within the WHO guideline limits at some points as rainfall progresses except the pH. All the components of rainwater quality measured during the study showed higher concentrations during the early stages of rainfall and reduce as time progresses. There was a downward trend in terms of pH as rain progressed, with 18% of the samples recording pH below the WHO limit of 6.5-8.0. It was observed that iron concentration was above the WHO threshold value of 0.3 mg/l on occasions of heavy rains. The results revealed that most of physicochemical characteristics of rainwater samples were generally below the WHO threshold, as such, the rainwater characteristics showed satisfactory conditions in terms of physicochemical constituents. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=conductivity" title="conductivity">conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=pH" title=" pH"> pH</a>, <a href="https://publications.waset.org/abstracts/search?q=physicochemical" title=" physicochemical"> physicochemical</a>, <a href="https://publications.waset.org/abstracts/search?q=rainwater%20quality" title=" rainwater quality"> rainwater quality</a>, <a href="https://publications.waset.org/abstracts/search?q=TDS" title=" TDS"> TDS</a> </p> <a href="https://publications.waset.org/abstracts/3268/progressive-changes-in-physico-chemical-constituent-of-rainwater-a-case-study-at-oyoko-a-rural-community-in-ghana" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3268.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">269</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">536</span> Genoprotective Effect of Lepidium sativum L. Seed Methanolic Extract on Cyclophosphamide-Induced DNA Damage in Mice and Characterization of Its Flavonoidal Content</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Iman%20A.%20A.%20Kassem">Iman A. A. Kassem</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayman%20A.%20Farghaly"> Ayman A. Farghaly</a>, <a href="https://publications.waset.org/abstracts/search?q=Zeinab%20M.%20Hassan"> Zeinab M. Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=Farouk%20R.%20Melek"> Farouk R. Melek</a>, <a href="https://publications.waset.org/abstracts/search?q=Neveen%20S.%20Ghaly"> Neveen S. Ghaly</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lipidium sativum L, an annual herb that grows to 50 cm, is known as an important member of family Brassicaceae. Besides its nutritional value, the seeds were widely used in folk medicine for treatment of cough, asthma, and headache. It was also reported to possess hypocholesterolemic, anti-inflammatory, antidiarrheal, antimicrobial and anticancer activities. In this study, the genoprotective properties of L. sativum seed methanolic extract (LSME) were evaluated in vivo. Three groups of mice were given LSME for five consecutive days at the three dose levels 25, 50 and 100 mg/kg b.wt. The three groups were then injected intraperitoneally with cyclophosphamide at a dose of 20 mg/kg b.wt. to induce DNA damage. A group received only cyclophosphamide (20 mg/kg b.wt.) served as control. LSME significantly inhibited the DNA aberrations in mice caused by cyclophosphamide in a dose-dependent manner in the two groups that received LSME at 50 and 100 mg/kg b.wt. dose levels. The chromosomal aberrations' inhibitory indices were calculated as 18 and 31 in mice bone marrow cells and 27 and 48 in mice spermatocytes, respectively. Phytochemical examination carried out by us revealed that flavonoids were the main chemical constituents of LSME. The major flavonoids kaempferol, kaempferol-3-O-rhamnoside, kaempferol-3-O-glucoside, quercetin, and quercetin-3-O-glucoside were isolated and characterized. It was concluded that the genoprotective effect of LSME might be attributed to the presence of flavonoids which are well-known for their antioxidant properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cyclophosphamide" title="cyclophosphamide">cyclophosphamide</a>, <a href="https://publications.waset.org/abstracts/search?q=flavonoids" title=" flavonoids"> flavonoids</a>, <a href="https://publications.waset.org/abstracts/search?q=genoprotective%20effect" title=" genoprotective effect"> genoprotective effect</a>, <a href="https://publications.waset.org/abstracts/search?q=Lepidium%20sativum" title=" Lepidium sativum"> Lepidium sativum</a> </p> <a href="https://publications.waset.org/abstracts/106019/genoprotective-effect-of-lepidium-sativum-l-seed-methanolic-extract-on-cyclophosphamide-induced-dna-damage-in-mice-and-characterization-of-its-flavonoidal-content" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106019.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">158</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">535</span> Antimicrobial Activity of Nauclea lotifolia (African Peach) Crude Extracts against Some Pathogenic Microorganism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Isah%20Legbo">Muhammad Isah Legbo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The phytochemical screening and antimicrobial activity of Nauclea lotifolia fruit, leaf and stem-bark extracts at various concentration of (20.0,10.0, 5.0, and 2.5 mg/ml) were evaluated against some pathogenic microorganisms such as Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Staphylococcus aureus, Aspergillus niger and Candida albicans. The antimicrobial activity was assayed using agar well diffusion method. The result obtained show appreciable inhibitory effort of acetone, aqueous and methanolic extracts of Nauclea lotifolia. However, result obtained was less active compared to that of the control antibiotic (Ciprofloxacillin). The minimum inhibitory concentration (MIC) was determined using serial doubling dilution method and ranged from 5.0-10.0mg/ml, while the minimum bactericidal concentration (MBC) was determined by plating various dilution of extracts without turbidity and the result ranged from 5.0-7.5mg/ml. The phytochemical screening revealed the presence of alkaloid, anthraquinones, flavonoids, resin, steroid and saponin. The activities of the plant extract therefore justify their utilization in the treatment of various ailments associated with the test organism. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nauclea" title="Nauclea">Nauclea</a>, <a href="https://publications.waset.org/abstracts/search?q=lotifolia" title=" lotifolia"> lotifolia</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial" title=" antimicrobial"> antimicrobial</a>, <a href="https://publications.waset.org/abstracts/search?q=pathogens" title=" pathogens"> pathogens</a>, <a href="https://publications.waset.org/abstracts/search?q=saponin" title=" saponin"> saponin</a>, <a href="https://publications.waset.org/abstracts/search?q=extract" title=" extract"> extract</a> </p> <a href="https://publications.waset.org/abstracts/49347/antimicrobial-activity-of-nauclea-lotifolia-african-peach-crude-extracts-against-some-pathogenic-microorganism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/49347.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">414</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">534</span> Antimicrobial Value of Olax subscorpioidea and Bridelia ferruginea on Micro-Organism Isolates of Dental Infection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20C.%20Orabueze">I. C. Orabueze</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20A.%20Amudalat"> A. A. Amudalat</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20A.%20%20Adesegun"> S. A. Adesegun</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20A.%20Usman"> A. A. Usman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dental and associated oral diseases are increasingly affecting a considerable portion of the population and are considered some of the major causes of tooth loss, discomfort, mouth odor and loss of confidence. This study focused on the ethnobotanical survey of medicinal plants used in oral therapy and evaluation of the antimicrobial activities of methanolic extracts of two selected plants from the survey for their efficacy against dental microorganisms. The ethnobotanical survey was carried out in six herbal markets in Lagos State, Nigeria by oral interviewing and information obtained from an old family manually complied herbal medication book. Methanolic extracts of Olax subscorpioidea (stem bark) and Bridelia ferruginea (stem bark) were assayed for their antimicrobial activities against clinical oral isolates (Aspergillus fumigatus, Candida albicans, Streptococcus spp, Staphylococcus aureus, Lactobacillus acidophilus and Pseudomonas aeruginosa). In vitro microbial technique (agar well diffusion method and minimum inhibitory concentration (MIC) assay) were employed for the assay. Chlorhexidine gluconate was used as the reference drug for comparison with the extract results. And the preliminary phytochemical screening of the constituents of the plants were done. The ethnobotanical survey produced plants (28) of diverse family. Different parts of plants (seed, fruit, leaf, root, bark) were mentioned but 60% mentioned were either the stem or the bark. O. subscorpioidea showed considerable antifungal activity with zone of inhibition ranging from 2.650 – 2.000 cm against Aspergillus fumigatus but no such encouraging inhibitory activity was observed in the other assayed organisms. B. ferruginea showed antibacterial sensitivity against Streptococcus spp, Staphylococcus aureus, Lactobacillus acidophilus and Pseudomonas aeruginosa with zone of inhibitions ranging from 3.400 - 2.500, 2.250 - 1.600, 2.700 - 1.950, 2.225 – 1.525 cm respectively. The minimum inhibitory concentration of O. subscorpioidea against Aspergillus fumigatus was 51.2 mg ml-1 while that of B. ferruginea against Streptococcus spp was 0.1mg ml-1 and for Staphylococcus aureus, Lactobacillus acidophilus and Pseudomonas aeruginosa were 25.6 mg ml-1. A phytochemical analysis reveals the presence of alkaloids, saponins, cardiac glycoside, tannins, phenols and terpenoids in both plants, with steroids only in B. ferruginea. No toxicity was observed among mice given the two methanolic extracts (1000 mg Kg-1) after 21 days. The barks of both plants exhibited antimicrobial properties against periodontal diseases causing organisms assayed, thus up-holding their folkloric use in oral disorder management. Further research could be done viewing these extracts as combination therapy, checking for possible synergistic value in toothpaste and oral rinse formulations for reducing oral bacterial flora and fungi load. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activities" title="antimicrobial activities">antimicrobial activities</a>, <a href="https://publications.waset.org/abstracts/search?q=Bridelia%20ferruginea" title=" Bridelia ferruginea"> Bridelia ferruginea</a>, <a href="https://publications.waset.org/abstracts/search?q=dental%20disinfection" title=" dental disinfection"> dental disinfection</a>, <a href="https://publications.waset.org/abstracts/search?q=methanolic%20extract" title=" methanolic extract"> methanolic extract</a>, <a href="https://publications.waset.org/abstracts/search?q=Olax%20subscorpioidea" title=" Olax subscorpioidea"> Olax subscorpioidea</a>, <a href="https://publications.waset.org/abstracts/search?q=ethnobotanical%20survey" title=" ethnobotanical survey"> ethnobotanical survey</a> </p> <a href="https://publications.waset.org/abstracts/46901/antimicrobial-value-of-olax-subscorpioidea-and-bridelia-ferruginea-on-micro-organism-isolates-of-dental-infection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46901.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">244</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">533</span> Dietary Intake and the Risk of Hypertriglyceridemia in Adults: Tehran Lipid and Glucose Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Parvin%20Mirmiran">Parvin Mirmiran</a>, <a href="https://publications.waset.org/abstracts/search?q=Zahra%20Bahadoran"> Zahra Bahadoran</a>, <a href="https://publications.waset.org/abstracts/search?q=Sahar%20Mirzae"> Sahar Mirzae</a>, <a href="https://publications.waset.org/abstracts/search?q=Fereidoun%20Azizi"> Fereidoun Azizi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background and aim: Lifestyle factors, especially dietary intakes play an important role in metabolism of lipids and lipoproteins. In this study, we assessed the association between dietary factors and 3-year changes of serum triglycerides (TG), HDL-C and the atherogenic index of plasma among Iranian adults. This longitudinal study was conducted on 1938 subjects, aged 19-70 years, who participated in the Tehran Lipid and Glucose Study. Demographics, anthropometrics and biochemical measurements including serum TG were assessed at baseline (2006-2008) and after a 3-year follow-up (2009-2011). Dietary data were collected by using a 168-food item, validated semi-quantitative food frequency questionnaire at baseline. The risk of hypertriglyceridemia in the quartiles of dietary factors was evaluated using logistic regression models with adjustment for age, gender, body mass index, smoking, physical activity and energy intakes. Results: Mean age of the participants at baseline was 41.0±13.0 y. Mean TG and HDL-C at baseline was 143±86 and 42.2±10.0 mg/dl, respectively. Three-year change of serum TG were inversely related energy intake from phytochemical rich foods, whole grains, and legumes (P<0.05). Higher intakes compared to lower ones of dietary fiber and phytochemical-rich foods had similar impact on decreased risk of hyper-triglyceridemia (OR=0.58, 95% CI=0.34-1.00). Higher- compared to lower-dietary sodium to potassium ratios (Na/K ratio) increased the risk of hypertriglyceridemia by 63% (OR=0.1.63, 95% CI= 0.34-1.00). Conclusion: Findings showed that higher intakes of fiber and phytochemical rich foods especially whole grain and legumes could have protective effects against lipid disorders; in contrast higher sodium to potassium ratio had undesirable effect on triglycerides. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lipid%20disorders" title="lipid disorders">lipid disorders</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertriglyceridemia" title=" hypertriglyceridemia"> hypertriglyceridemia</a>, <a href="https://publications.waset.org/abstracts/search?q=diet" title=" diet"> diet</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20science" title=" food science"> food science</a> </p> <a href="https://publications.waset.org/abstracts/21554/dietary-intake-and-the-risk-of-hypertriglyceridemia-in-adults-tehran-lipid-and-glucose-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21554.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">468</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">532</span> Phytochemical Screening and Evaluation of Antimicrobial and Antioxidant Activity of Anethum graveolens L. (Dill) Plant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Radhika%20S.%20Oke">Radhika S. Oke</a>, <a href="https://publications.waset.org/abstracts/search?q=Rebecca%20S.%20Thombre"> Rebecca S. Thombre</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Medicinal plants and herbs have a great history of their utility as remedy for treatment of variety of ailments. Secondary metabolites present in these plants are responsible for their medicinal activity. In the present investigation, phytochemical screening of aqueous and alcoholic leaf extract of Anethum graveolens L. was performed. Total phenolic content and total antioxidant activity of the extracts was quantitatively estimated by Folin-Ciocalteau method and DPPH (1, 1-Diphenyl-2-picryl hydrazyl) method respectively. Qualitative tests suggested that Alkaloids, tannins and phenolic compounds were present in all the extracts of the plant. Aqueous extracts was found to have more phytochemicals as compared to alcoholic extracts. Extract of Anethum graveolens L. was found to contain good amount phenolics and exhibited antioxidant activity. The extracts also demonstrated potent antimicrobial activity against selected gram positive and negative bacteria. The study revealed the potential application of Anethum graveolens L. (Dill) in medicine and health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anethum%20graveolens%20L." title="Anethum graveolens L.">Anethum graveolens L.</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=medicine%20and%20health" title=" medicine and health "> medicine and health </a> </p> <a href="https://publications.waset.org/abstracts/6499/phytochemical-screening-and-evaluation-of-antimicrobial-and-antioxidant-activity-of-anethum-graveolens-l-dill-plant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6499.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">506</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">531</span> Phenolic Composition and Contribution of Individual Compounds to Antioxidant Activity of Malus domestica Borkh Fruit Cultivars</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Raudone%20Lina">Raudone Lina</a>, <a href="https://publications.waset.org/abstracts/search?q=Raudonis%20Raimondas"> Raudonis Raimondas</a>, <a href="https://publications.waset.org/abstracts/search?q=Liaudanskas%20Mindaugas"> Liaudanskas Mindaugas</a>, <a href="https://publications.waset.org/abstracts/search?q=Pukalskas%20Audrius"> Pukalskas Audrius</a>, <a href="https://publications.waset.org/abstracts/search?q=Viskelis%20Pranas"> Viskelis Pranas</a>, <a href="https://publications.waset.org/abstracts/search?q=Janulis%20Valdimaras"> Janulis Valdimaras </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Human health fortification, its protection and disease prophylaxis are the main problems of the health care systems. Plant origin materials and their preparations are applied for the prevention of the common diseases. Oxidative stress takes part in the pathogenesis of many autoimmune, neurodegenerative, tumor and ageing processes. The antioxidants are able to protect the human body from the free radicals and to stop the progression of numerous chronic diseases. The research of plant origin materials is relevant for the search of natural antioxidants. A group of compounds that gained scientific attention due to antioxidant properties and effects on human health are phenolic compounds. Phenolic compounds are widely abundant in various parts of plants, i.e. leaves, stems, roots, flowers and fruits. Most commonly consumed fruits all over the world are apples. It is very important to analyze the antioxidant activity of apples as they are extensively used in the prevention of various diseases. The aim of this study was to determine the antioxidant profiles of Malus domestica Borkh fruit cultivars (Aldas, Auksis, Connel Red, Ligol, Lodel, Rajka) and to identify the phenolic compounds with potent contribution to antioxidant activity. Nineteen constituents were identiﬁed in apple cultivars using ultra high performance liquid chromatography coupled to quadruple and time-of-ﬂight mass spectrometers (UPLC–QTOF–MS). Phytochemical profile was constituted of phenolic acids, procyanidins, quercetin derivatives and dihydrochalcones. Reducing and radical scavenging activities of individual constituents were determined using high performance liquid chromatography (HPLC) coupled to post-column FRAP and ABTS assay, respectively. Significant differences of total radical scavenging and reducing activity (expressed as trolox equivalents, TE µmol/g) were determined between the investigated cultivars. Chlorogenic acid and complex of procyanidins were the main contributors to antioxidant activity determining up to 35 % and 55 % of total TE values, respectively. Determined phenolic composition and antioxidant activity significantly depend on apple cultivars. It is important to determine the individual compounds that are significant for antioxidant activity and that could be investigated in vivo systems. The identification of the antioxidants provides information for the further research of standardized extracts that could be used for pharmaceutical preparations with specific phenolic traits. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=FRAP" title="FRAP">FRAP</a>, <a href="https://publications.waset.org/abstracts/search?q=ABTS" title=" ABTS"> ABTS</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic" title=" phenolic"> phenolic</a>, <a href="https://publications.waset.org/abstracts/search?q=apples" title=" apples"> apples</a>, <a href="https://publications.waset.org/abstracts/search?q=chlorogenic%20acid" title=" chlorogenic acid"> chlorogenic acid</a> </p> <a href="https://publications.waset.org/abstracts/16464/phenolic-composition-and-contribution-of-individual-compounds-to-antioxidant-activity-of-malus-domestica-borkh-fruit-cultivars" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16464.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">408</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">530</span> A Molecular Modelling Approach for Identification of Lead Compound from Rhizomes of Glycosmis Pentaphylla for Skin Cancer Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rahul%20Shrivastava">Rahul Shrivastava</a>, <a href="https://publications.waset.org/abstracts/search?q=Manish%20Tripathi"> Manish Tripathi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohmmad%20Yasir"> Mohmmad Yasir</a>, <a href="https://publications.waset.org/abstracts/search?q=Shailesh%20Singh"> Shailesh Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Life style changes and depletion in atmospheric ozone layer in recent decades lead to increase in skin cancer including both melanoma and nonmelanomas. Natural products which were obtained from different plant species have the potential of anti skin cancer activity. In regard of this, present study focuses the potential effect of Glycosmis pentaphylla against anti skin cancer activity. Different Phytochemical constituents which were present in the roots of Glycosmis pentaphylla were identified and were used as ligands after sketching of their structures with the help of ACD/Chemsketch. These ligands are screened for their anticancer potential with proteins which are involved in skin cancer effects with the help of pyrx software. After performing docking studies, results reveal that Noracronycine secondary metabolite of Glycosmis pentaphylla shows strong affinity of their binding energy with Ribosomal S6 Kinase 2 (2QR8) protein. Ribosomal S6 Kinase 2 (2QR8) has an important role in the cell proliferation and transformation mediated through by N-terminal kinase domain and was induced by the tumour promoters such as epidermal growth factor. It also plays a key role in the neoplastic transformation of human skin cells and in skin cancer growth. Noracronycine interact with THR-493 and MET-496 residue of Ribosomal S6 Kinase 2 protein with binding energy ΔG = -8.68 kcal/mole. Thus on the basis of this study we can say that Noracronycine which present in roots of Glycosmis pentaphylla can be used as lead compound against skin cancer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glycosmis%20pentaphylla" title="glycosmis pentaphylla">glycosmis pentaphylla</a>, <a href="https://publications.waset.org/abstracts/search?q=pyrx" title=" pyrx"> pyrx</a>, <a href="https://publications.waset.org/abstracts/search?q=ribosomal%20s6%20kinase" title=" ribosomal s6 kinase"> ribosomal s6 kinase</a>, <a href="https://publications.waset.org/abstracts/search?q=skin%20cancer" title=" skin cancer"> skin cancer</a> </p> <a href="https://publications.waset.org/abstracts/43676/a-molecular-modelling-approach-for-identification-of-lead-compound-from-rhizomes-of-glycosmis-pentaphylla-for-skin-cancer-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43676.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">303</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">529</span> Experimental Investigation on Flexural Properties of Bamboo Fibres Polypropylene Composites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tigist%20Girma%20Kidane">Tigist Girma Kidane</a>, <a href="https://publications.waset.org/abstracts/search?q=Yalew%20Dessalegn%20Asfaw"> Yalew Dessalegn Asfaw</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Abstract: The current investigation aims to measure the longitudinal and transversal three-point bending tests of bamboo fibres polypropylene composites (BFPPCs) for the application of the automobile industry. Research has not been done on the properties of Ethiopian bamboo fibres for the utilization of composite development. The samples of bamboo plants have been harvested in 3–groups of age, 2–harvesting seasons, and 3–regions of bamboo species. Roll milling machine used for the extraction of bamboo fibres which has been developed by the authors. Chemical constituents measured using gravimetric methods. Unidirectional bamboo fibres prepreg has been produced using PP and hot press machine, then BFPPCs were produced using 6 layers of prepregs at automatic hot press machine. Age, harvesting month, and bamboo species have a statistically significant effect on the longitudinal and transverse flexural strength (FS), modulus of elasticity (MOE), and failure strain at α = 0.05 as evaluated by one-way ANOVA. 2–yrs old of BFPPCs have the highest FS and MOE, whereas November has the highest value of flexural properties. The highest to the lowest FS and MOE of BFPPCs has measured in Injibara, Mekaneselam, and Kombolcha, respectively. The transverse 3-point bending test has a lower FS and MOE compared to the longitudinal direction. The chemical constituents of Injibara, Mekaneselam, and Kombolcha have the highest to the lowest, respectively. 2-years old of bamboo fibres has the highest chemical constituent. The chemical constituents improved the flexural properties. Bamboo fibres in Ethiopia can be relevant for composite development, which has been applied in the area of requiring higher flexural properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=age" title="age">age</a>, <a href="https://publications.waset.org/abstracts/search?q=bamboo%20species" title=" bamboo species"> bamboo species</a>, <a href="https://publications.waset.org/abstracts/search?q=flexural%20properties" title=" flexural properties"> flexural properties</a>, <a href="https://publications.waset.org/abstracts/search?q=harvesting%20season" title=" harvesting season"> harvesting season</a>, <a href="https://publications.waset.org/abstracts/search?q=polypropylene" title=" polypropylene"> polypropylene</a> </p> <a href="https://publications.waset.org/abstracts/183518/experimental-investigation-on-flexural-properties-of-bamboo-fibres-polypropylene-composites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183518.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">52</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">528</span> Rooting Out Breast Cancer by Repressing ER Gene Expression: Correlating Bioactivity of Pomegranate Rind with Chemical Constituents Identified by HPLC-MS/MS</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alaa%20M.%20M.%20Badr%20Eldin">Alaa M. M. Badr Eldin</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20I.%20Ezzat"> Marwa I. Ezzat</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20S.%20Sedeek"> Mohammed S. Sedeek</a>, <a href="https://publications.waset.org/abstracts/search?q=Manal%20S.%20Afifi"> Manal S. Afifi</a>, <a href="https://publications.waset.org/abstracts/search?q=Omar%20M.%20Sabry"> Omar M. Sabry</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cytotoxic activity of the total methanol extract against breast cancer cell line MCF-7 was amazing IC50 at 54 ug/ml. 130 polyphenolic compounds were tentatively identified in pomegranate peel (Punica granatum L.) methanol extract using HPLC-MS/MS technique. The antiestrogenic activity of the polyphenolic constituents found in pomegranate extract was confirmed experimentally in-vitro and by the in-silico molecular docking using gallagic acid, ellagic acid, and Punicalagin as these are considered model compounds confirmed in pomegranate peel extract. The methanolic extract was found to suppress ER, TGF-β, and NF-kB in-vitro gene expression strongly, and that was verified by qPCR and Western Blot gel electrophoresis techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HPLC-MS%2FMS" title="HPLC-MS/MS">HPLC-MS/MS</a>, <a href="https://publications.waset.org/abstracts/search?q=pomegranate" title=" pomegranate"> pomegranate</a>, <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title=" breast cancer"> breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=ovarian%20cancer" title=" ovarian cancer"> ovarian cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=ER" title=" ER"> ER</a>, <a href="https://publications.waset.org/abstracts/search?q=TGF-%CE%B2" title=" TGF-β"> TGF-β</a>, <a href="https://publications.waset.org/abstracts/search?q=NF-kB" title=" NF-kB"> NF-kB</a> </p> <a href="https://publications.waset.org/abstracts/158003/rooting-out-breast-cancer-by-repressing-er-gene-expression-correlating-bioactivity-of-pomegranate-rind-with-chemical-constituents-identified-by-hplc-msms" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158003.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">102</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">527</span> Effect of Ultrasound and Enzyme on the Extraction of Eurycoma longifolia (Tongkat Ali)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=He%20Yuhai">He Yuhai</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Ziad%20Bin%20Sulaiman"> Ahmad Ziad Bin Sulaiman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tongkat Ali, or Eurycoma longifolia, is a traditional Malay and Orang Asli herb used as aphrodisiac, general tonic, anti-Malaria, and anti-Pyretic. It has been recognized as a cashcrop by Malaysia due to its high value for the pharmaceutical use. In Tongkat Ali, eurycomanone, a quassinoid is usually chosen as a marker phytochemical as it is the most abundant phytochemical. In this research, ultrasound and enzyme were used to enhance the extraction of Eurycomanone from Tongkat Ali. Ultrasonic assisted extraction (USE) enhances extraction by facilitating the swelling and hydration of the plant material, enlarging the plant pores, breaking the plant cell, reducing the plant particle size and creating cavitation bubbles that enhance mass transfer in both the washing and diffusion phase of extraction. Enzyme hydrolyses the cell wall of the plant, loosening the structure of the cell wall, releasing more phytochemicals from the plant cell, enhancing the productivity of the extraction. Possible effects of ultrasound on the activity of the enzyme during the hydrolysis of the cell wall is under the investigation by this research. The extracts was analysed by high performance liquid chromatography for the yields of Eurycomanone. In this whole process, the conventional water extraction was used as a control of comparing the performance of the ultrasound and enzyme assisted extraction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ultrasound" title="ultrasound">ultrasound</a>, <a href="https://publications.waset.org/abstracts/search?q=enzymatic" title=" enzymatic"> enzymatic</a>, <a href="https://publications.waset.org/abstracts/search?q=extraction" title=" extraction"> extraction</a>, <a href="https://publications.waset.org/abstracts/search?q=Eurycoma%20longifolia" title=" Eurycoma longifolia"> Eurycoma longifolia</a> </p> <a href="https://publications.waset.org/abstracts/28783/effect-of-ultrasound-and-enzyme-on-the-extraction-of-eurycoma-longifolia-tongkat-ali" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28783.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">418</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">526</span> Phytochemical Screening, and Antimicrobial Evaluation of Bioactive Compounds from Red Millipede (Trigoniulus corallinus)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Y.%20B.%20Idris">Y. B. Idris</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Sirajo"> M. Sirajo</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20G.%20Hassan"> L. G. Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20Izuagie"> T. Izuagie</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20Muktar"> T. Muktar</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Lawal"> I. Lawal</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20U.%20Abubakar"> A. U. Abubakar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study investigates the extraction, phytochemical composition, and antimicrobial activity of bioactive compounds from red millipedes using three different solvents: n-Hexane, Chloroform, and Methanol. The largest yield was obtained from the methanol extract, which had percentage yields of 0.8%, 2.2%, and 5.6%, respectively. Terpenoids and sterols were found in all extracts according to preliminary zoochemical screening, but only the methanol extract included saponins and phenols. With a maximum zone of inhibition of 9 mm at 1000 µg/ml, antimicrobial susceptibility tests revealed that the methanol extract had the strongest antibacterial activity, especially against Escherichia coli and Staphylococcus aureus. Significant activity was also shown by the n-hexane extract, although the chloroform extract had only mild antibacterial activity. Tests for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) verified that the methanol extract was more effective than the other extracts, particularly against S. aureus and S. typhi. None of the extracts, nonetheless, showed any discernible antifungal action. The potential of red millipede extracts, especially those based on methanol, as a source of antimicrobial chemicals for use in the future is highlighted by this work. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=millipedes" title="millipedes">millipedes</a>, <a href="https://publications.waset.org/abstracts/search?q=defensive%20extraction" title=" defensive extraction"> defensive extraction</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial" title=" antibacterial"> antibacterial</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal" title=" antifungal"> antifungal</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial" title=" antimicrobial"> antimicrobial</a>, <a href="https://publications.waset.org/abstracts/search?q=minimum%20inhibitory%20concentration%20%28MIC%29" title=" minimum inhibitory concentration (MIC)"> minimum inhibitory concentration (MIC)</a>, <a href="https://publications.waset.org/abstracts/search?q=minimum%20bacterial%20concentration%20%28MBC%29" title=" minimum bacterial concentration (MBC)"> minimum bacterial concentration (MBC)</a> </p> <a href="https://publications.waset.org/abstracts/192970/phytochemical-screening-and-antimicrobial-evaluation-of-bioactive-compounds-from-red-millipede-trigoniulus-corallinus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/192970.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">14</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">525</span> A phytochemical and Biological Study of Viscum schemperi Engl. Growing in Saudi Arabia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manea%20A.%20I.%20Alqrad">Manea A. I. Alqrad</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Sirwi"> Alaa Sirwi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sabrin%20R.%20M.%20Ibrahim"> Sabrin R. M. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hossam%20M.%20Abdallah"> Hossam M. Abdallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamal%20A.%20Mohamed"> Gamal A. Mohamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Phytochemical study of the methanolic extract of the air dried powdered of the parts of Viscum schemperi Engl. (Family: Viscaceae) using different chromatographic techniques led to the isolation of five compounds: -amyrenone (1), betulinic acid (2), (3β)-olean-12-ene-3,23-diol (3), -oleanolic acid (4), and α-oleanolic acid (5). Their structures were established based on physical, chemical, and spectral data. Anti-inflammatory and anti-apoptotic activities of oleanolic acid in a mouse model of acute hepatorenal damage were assessed. This study showed the efficacy of oleanolic acid to counteract thioacetamide-induced hepatic and kidney injury in mice through the reduction of hepatocyte oxidative damage, suppression of inflammation, and apoptosis. More importantly, oleanolic acid suppressed thioacetamide-induced hepatic and kidney injury by inhibiting NF-κB/TNF-α-mediated inflammation/apoptosis and enhancing SIRT1/Nrf2/Heme-oxygenase signalling pathway. These promising pharmacological activities suggest the potential use of oleanolic acid against hepatorenal damage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=oleanolic%20acid" title="oleanolic acid">oleanolic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=viscum%20schimperi" title=" viscum schimperi"> viscum schimperi</a>, <a href="https://publications.waset.org/abstracts/search?q=thioacetamide" title=" thioacetamide"> thioacetamide</a>, <a href="https://publications.waset.org/abstracts/search?q=SIRT1%2FNrf2%2FNF-%CE%BAB" title=" SIRT1/Nrf2/NF-κB"> SIRT1/Nrf2/NF-κB</a>, <a href="https://publications.waset.org/abstracts/search?q=hepatorenal%20damage" title=" hepatorenal damage"> hepatorenal damage</a> </p> <a href="https://publications.waset.org/abstracts/169183/a-phytochemical-and-biological-study-of-viscum-schemperi-engl-growing-in-saudi-arabia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169183.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">524</span> Phytochemical Screening and Antimicrobial Activity of Limeum indicum and Euphorbia granulata</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noshaba%20Dilbar">Noshaba Dilbar</a>, <a href="https://publications.waset.org/abstracts/search?q=Hina%20Ashraf"> Hina Ashraf</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Medicinal plants are considered as rich source of ingredients which can be used in drug development and synthesis. Moreover, these plants play a vital role in the development of human culture of using ayurvedic medicines around the whole world. Among all plants, dessert plants are being proved as effective source of ayurvedic medicines and remedy against many diseases. Considering the fact, two plant species Limium indicum and Euphorbia granulata were taken from Cholistan dessert of Bahawalpur, Pakistan. Firstly, phytochemical screening was done by making dry and fresh plant extracts in five different solvents i.e Petroleum ether, benzene, chloroform, ethanol and methanol. Standard confirmation tests for all compounds were applied for analysis. Results revealed the presence of high range of bioactive compounds such as alakaloids, terpenoids, glycosides, steroids, flavonoids, saponins, phytosterols, oxalic acid, anthocyanin and quinone in both plants. Best results were obtained by methanolic, chloroform and petroleum ether extracts and methanolic, ethanolic and benzene extracts of Limium indicum and Euphorbia granulate respectively. Considering the results, methanolic extracts of both plants were further analysed for antibacterial activity. Plants were analysed against four pathogens including Escherchia coli, Proteus vulgaris, Klebsiella pneumonia and Pseudomonas aruginosa using disc diffusion method. Limium indicum showed highly significant activity against all pathogens while Euphorbia granulata showed significant activity against Klebsiella pneumonia and Proteus vulgaris but lesser against Escherchia coli and Pseudomonas aruginosa. MIC of extracts against each positive bacterium was calculated and recorded. Present plants can be considered for making useful drugs but further studies are needed to isolate active agents from plant extracts for drug development. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title="antibacterial activity">antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Euphorbia%20granulata" title=" Euphorbia granulata"> Euphorbia granulata</a>, <a href="https://publications.waset.org/abstracts/search?q=Limium%20indicum" title=" Limium indicum"> Limium indicum</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening"> phytochemical screening</a> </p> <a href="https://publications.waset.org/abstracts/122769/phytochemical-screening-and-antimicrobial-activity-of-limeum-indicum-and-euphorbia-granulata" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/122769.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">118</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">523</span> Evaluation of Genetic Fidelity and Phytochemical Profiling of Micropropagated Plants of Cephalantheropsis obcordata: An Endangered Medicinal Orchid </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gargi%20Prasad">Gargi Prasad</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashiho%20A.%20Mao"> Ashiho A. Mao</a>, <a href="https://publications.waset.org/abstracts/search?q=Deepu%20Vijayan"> Deepu Vijayan</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Mandal"> S. Mandal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The main objective of the present study was to optimize and develop an efficient protocol for in vitro propagation of a medicinally important orchid Cephalantheropsis obcordata (Lindl.) Ormerod along with genetic stability analysis of regenerated plants. This plant has been traditionally used in Chinese folk medicine and the decoction of whole plant is known to possess anticancer activity. Nodal segments used as explants were inoculated on Murashige and Skoog (MS) medium supplemented with various concentrations of isopentenyl adenine (2iP). The rooted plants were successfully acclimatized in the greenhouse with 100% survival rate. Inter-simple sequence repeats (ISSR) markers were used to assess the genetic fidelity of in vitro raised plants and the mother plant. It was revealed that monomorphic bands showing the absence of polymorphism in all in vitro raised plantlets analyzed, confirming the genetic uniformity among the regenerants. Phytochemical analysis was done to compare the antioxidant activities and HPLC fingerprinting assay of 80% aqueous ethanol extract of the leaves and stem of in vitro and in vivo grown C. obcordata. The extracts of the plants were examined for their antioxidant activities by using free radical 1, 1-diphenyl-2-picryl hydrazyl (DPPH) scavenging method, 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging ability, reducing power capacity, estimation of total phenolic content, flavonoid content and flavonol content. A simplified method for the detection of ascorbic acid, phenolic acids and flavonoids content was also developed by using reversed phase high-performance liquid chromatography (HPLC). This is the first report on the micropropagation, genetic integrity study and quantitative phytochemical analysis of in vitro regenerated plants of C. obcordata. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Cephalantheropsis%20obcordata" title="Cephalantheropsis obcordata">Cephalantheropsis obcordata</a>, <a href="https://publications.waset.org/abstracts/search?q=genetic%20fidelity" title=" genetic fidelity"> genetic fidelity</a>, <a href="https://publications.waset.org/abstracts/search?q=ISSR%20markers" title=" ISSR markers"> ISSR markers</a>, <a href="https://publications.waset.org/abstracts/search?q=HPLC" title=" HPLC "> HPLC </a> </p> <a href="https://publications.waset.org/abstracts/92601/evaluation-of-genetic-fidelity-and-phytochemical-profiling-of-micropropagated-plants-of-cephalantheropsis-obcordata-an-endangered-medicinal-orchid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92601.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">156</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">522</span> Bioactive, Nutritional and Heavy Metal Constituents of Some Edible Mushrooms Found in Abia State of Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20C.%20Okwulehie">I. C. Okwulehie</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20A.%20Ogoke"> J. A. Ogoke</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The phytocemical, mineral, proximate and heavy metals compositions of six edible and non-edible species of mushrooms were investigated. Fully fleshy mushrooms were used for the analysis. On the averagely, the bioactive constituents of the mushrooms were as follows Alkaloids 0.12 ± 0.02 – 1.01 ± 03 %, Tannins 0.44 ± 0.09 – 1.38 ± 0.6,). Phenols,(0.13 ± 0.01 – 0.26± 0.00, Saponins 0.14 ± 0.03 – 0.32 ± 0.04%, Flavonoids 0.08 ± 0.02 – 0.34 ± 0.02%. The result of proximate composition indicated that the mushroom contained (5.17 ± 0.06 – 12.28 ± 0.16% protein, 0.16 ± 0.02 – 0.67 ± 0.02% fats, 1.06 ± 0.03 – 8.49 ± 0.03 % fibre, (62.06 ± 0.52 – 80.01 ± 4.71% and carbohydrate. The mineral composition of the mushrooms were as follows, calcium 81.49 ± 2.32 - .914 ± 2.32mg/100g, Magnesium(8 ± 1.39-24 ± 2.40mg/100g, Potassium 64.54 ± 0.43 – 164.54 ± 1.23 mg/100g, sodium 9.47 ± 0.12 – 30.97 ± 0.16 mg/100g, and Phosphorus 22.19 ± 0.57-53.2± 0.44 mg/100g. Heavy metals concentration indicated Cadmium 0.7-0.94ppm. Zinc 27.82 – 70.98 ppm. Lead 0.66 – 2.86ppm and Copper 1.8-22.32ppm. The result obtained indicates that the mushrooms are of good sources of phytochemicals, proximate and minerals needed for maintenance of good health and can also be exploited in manufacture of drugs. Heavy metals obtained indicate that when consume intentionally in high content may cause liver, kidney damage and even death. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioactive" title="bioactive">bioactive</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metals" title=" heavy metals"> heavy metals</a>, <a href="https://publications.waset.org/abstracts/search?q=mushroom" title=" mushroom"> mushroom</a>, <a href="https://publications.waset.org/abstracts/search?q=nutritive" title=" nutritive"> nutritive</a> </p> <a href="https://publications.waset.org/abstracts/10128/bioactive-nutritional-and-heavy-metal-constituents-of-some-edible-mushrooms-found-in-abia-state-of-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10128.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">424</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">521</span> Rhizome-Soaking with Plant-Derived Smoke-Water (Pdsw) And Karrikinolide Boosts the Essential-Oil Yield, Active Constituents and Leaf Physiological Parameters of Mentha Arvensis L</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sarika%20Singh">Sarika Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Moin%20Uddin"> Moin Uddin</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Masroor%20A.%20Khan"> M. Masroor A. Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Aman%20Sobia%20Chishti"> Aman Sobia Chishti</a>, <a href="https://publications.waset.org/abstracts/search?q=Sangram%20Singh"> Sangram Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Urooj%20Hassan%20Bhatt"> Urooj Hassan Bhatt</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mentha arvensis L. (Japanese mint) is a perennial plant carrying medicinal, aromatic, antiseptic, and anaesthetic properties. Plant-derived smoke-water (PDSW) plays a significant role in seed germination, seedling growth, and other physiological attributes. To ascertain the effect of PDSW and karrikinolide on Mentha arvensis L., a rhizome-soaking experiment was conducted on Mentha arvensis. Prior to planting, mint rhizomes were soaked for 24 hours with aqueous solutions of various concentrations of PDSW (1:125v/v, 1:250 v/v, 1:500 v/v, and 1:1000 v/v), karrikinolide (10-6M, 10⁻⁷M, 10⁻⁸M, and 10⁻⁹M) using double distilled water as control treatment. Rhizome soaking with 1:500 v/v concentration of PDSW and 10⁻⁸M concentration of KAR1 increased the growth attributes, including plant height, fresh weight, dry, leaf area, and leaf yield per plant of Mentha arvensis. Leaf physiological-parameters, viz. chlorophyll fluorescence, PSII activity, and total chlorophyll and carotenoid content, were also increased as a result of the application of this treatment PDSW (1:500 v/v) and KAR1 (10⁻⁸M). In addition, treatment with 1:500 v/v and 10⁻⁸M significantly increased the essential oil yield and active constituents of Mentha arvensis compared to the control. Results indicated that PDSW, being a cheap source of karrikins, might be successfully used to augment mint essential oil production. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=active%20constituents" title="active constituents">active constituents</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plant" title=" medicinal plant"> medicinal plant</a>, <a href="https://publications.waset.org/abstracts/search?q=mentha%20arvensis%20L" title=" mentha arvensis L"> mentha arvensis L</a> </p> <a href="https://publications.waset.org/abstracts/151837/rhizome-soaking-with-plant-derived-smoke-water-pdsw-and-karrikinolide-boosts-the-essential-oil-yield-active-constituents-and-leaf-physiological-parameters-of-mentha-arvensis-l" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151837.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">89</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">520</span> Antioxidative Effect of Bauhinia acuminata Water Extract Consumption in Rat</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amornnat%20Thuppia">Amornnat Thuppia</a>, <a href="https://publications.waset.org/abstracts/search?q=Pornrut%20Rabintossaporn"> Pornrut Rabintossaporn</a>, <a href="https://publications.waset.org/abstracts/search?q=Suphaket%20Saenthaweesuk"> Suphaket Saenthaweesuk</a>, <a href="https://publications.waset.org/abstracts/search?q=Nuntiya%20Somparn"> Nuntiya Somparn</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this present study was to determine the antioxidant effects and its mechanism of aqueous leaves extract of Bauhinia acuminata (BA) in rat. The extract was screened for its phytochemical contents and antioxidant activity in vitro. Moreover, the extract was studied in rats to evaluate its effects in vivo. Rats were orally administered with the extract at the dose of 50, 100 and 200 mg/kg for 28 days. Phytochemical screening of plant extracts showed the presence of saponin, alkaloid, cardiac glycosides, flavonoids, tannin and steroid compounds. The extract contained phenolic compounds 53.36 ± 1.01 mg of gallic acid equivalents per gram BA extract. The free radical scavenging activity assessed by DPPH assay gave IC50 of 44.47 ± 2.83 µg/mL, which is relatively lower than that of BHT with IC50 of 12.34 ± 1.14µg/mL. In the animals, the extract was well tolerated by the animals throughout the 28 days of study as shown by normal serum levels AST, ALP, ALT, BUN and Cr as well as normal histology of liver and pancreatic and kidney tissue. Significantly, reduction of serum oxidative stress markers malondialdehyde (MDA) was found in rat treated with BA extract compared with control. Taken together, this study provides evidence that Bauhinia acuminata (BA) exhibits direct antioxidant properties and induces cytoprotective enzyme in vivo. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bauhinia%20acuminata" title="Bauhinia acuminata">Bauhinia acuminata</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=malondialdehyde%20%28MDA%29" title=" malondialdehyde (MDA)"> malondialdehyde (MDA)</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20marker" title=" oxidative marker"> oxidative marker</a> </p> <a href="https://publications.waset.org/abstracts/69547/antioxidative-effect-of-bauhinia-acuminata-water-extract-consumption-in-rat" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69547.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">519</span> Understanding Health-Related Properties of Grapes by Pharmacokinetic Modelling of Intestinal Absorption</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sophie%20N.%20Selby-Pham">Sophie N. Selby-Pham</a>, <a href="https://publications.waset.org/abstracts/search?q=Yudie%20Wang"> Yudie Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Louise%20Bennett"> Louise Bennett</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Consumption of grapes promotes health and reduces the risk of chronic diseases due to the action of grape phytochemicals in regulation of Oxidative Stress and Inflammation (OSI). The bioefficacy of phytochemicals depends on their absorption in the human body. The time required for phytochemicals to achieve maximal plasma concentration (Tₘₐₓ) after oral intake reflects the time window of maximal bioefficacy of phytochemicals, with Tₘₐₓ dependent on physicochemical properties of phytochemicals. This research collated physicochemical properties of grape phytochemicals from white and red grapes to predict their Tₘₐₓ using pharmacokinetic modelling. The predicted values of Tₘₐₓ were then compared to the measured Tₘₐₓ collected from clinical studies to determine the accuracy of prediction. In both liquid and solid intake forms, white grapes exhibit a shorter Tₘₐₓ range (0.5-2.5 h) versus red grapes (1.5-5h). The prediction accuracy of Tₘₐₓ for grape phytochemicals was 33.3% total error of prediction compared to the mean, indicating high prediction accuracy. Pharmacokinetic modelling allows prediction of Tₘₐₓ without costly clinical trials, informing dosing frequency for sustained presence of phytochemicals in the body to optimize the health benefits of phytochemicals. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=absorption%20kinetics" title="absorption kinetics">absorption kinetics</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical" title=" phytochemical"> phytochemical</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20absorption%20prediction%20model" title=" phytochemical absorption prediction model"> phytochemical absorption prediction model</a>, <a href="https://publications.waset.org/abstracts/search?q=Vitis%20vinifera" title=" Vitis vinifera"> Vitis vinifera</a> </p> <a href="https://publications.waset.org/abstracts/95074/understanding-health-related-properties-of-grapes-by-pharmacokinetic-modelling-of-intestinal-absorption" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95074.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">518</span> Antibacterial and Antityrosinase Activity of Isolated Compounds from Stem Bark of Ficus platyphylla Del</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aminu%20Muhammad">Aminu Muhammad</a>, <a href="https://publications.waset.org/abstracts/search?q=Mustapha%20Ya%E2%80%99u"> Mustapha Ya’u</a>, <a href="https://publications.waset.org/abstracts/search?q=Hasnah%20Mohd%20Sirat"> Hasnah Mohd Sirat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> An investigation of the chemical constituents into the stem bark of Ficus platyphylla (Moraceae) has resulted in the isolation of hordenine, epicatechin, lupeol, lupeol acetate and α-amyrin acetate. Their structures were determined using spectroscopic data as well as comparison with literature data. The antibacterial assay has been tested against Gram positive and Gram negative bacteria, while the tyrosinase inhibition assay was examined using L-Dopa as a substrate of mushroom tyrosinase enzyme. hordenine, epicatechin, lupeol, lupeol acetate and α-amyrin acetate showed minimum inhibition concentration (MIC) values in the range of 225-900 µg/mL against the bacterial strains. Lupeol, lupeol acetate and α-amyrin acetate showed significant antityrosinase activity against mushroom tyrosinase enzyme with percent inhibition of 67.7%, 66.2% and 62.2%, respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibacterial" title="antibacterial">antibacterial</a>, <a href="https://publications.waset.org/abstracts/search?q=antityrosinase" title=" antityrosinase"> antityrosinase</a>, <a href="https://publications.waset.org/abstracts/search?q=chemical%20constituents" title=" chemical constituents"> chemical constituents</a>, <a href="https://publications.waset.org/abstracts/search?q=Ficus%20platyphylla" title=" Ficus platyphylla"> Ficus platyphylla</a> </p> <a href="https://publications.waset.org/abstracts/46753/antibacterial-and-antityrosinase-activity-of-isolated-compounds-from-stem-bark-of-ficus-platyphylla-del" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46753.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">268</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">517</span> Free Radical Scavenging, Antioxidant Activity, Phenolic, Alkaloids Contents and Inhibited Properties against α-Amylase and Invertase Enzymes of Stem Bark Extracts Coula edulis B</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eric%20Beyegue">Eric Beyegue</a>, <a href="https://publications.waset.org/abstracts/search?q=Boris%20Azantza"> Boris Azantza</a>, <a href="https://publications.waset.org/abstracts/search?q=Judith%20Laure%20Ngondi"> Judith Laure Ngondi</a>, <a href="https://publications.waset.org/abstracts/search?q=Julius%20E.%20Oben"> Julius E. Oben</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: It is clearly that phytochemical constituents of plants in relation exhibit free radical scavenging, antioxidant and glycosylation properties. This study investigated the in vitro antioxidant and free radical scavenging, inhibited activities against α-amylase and invertase enzymes of stem bark extracts C. edulis (Olacaceae). Methods: Four extracts (hexane, dichloromethane, ethanol and aqueous) from the barks of C. edulis were used in this study. Colorimetric in vitro methods were using for evaluate free radical scavenging activity DPPH, ABTS, NO, OH, antioxidant capacity, glycosylation activity, inhibition of α-amylase and invertase activities, phenolic, flavonoid and alkaloid contents. Results: C. edulis extracts (CEE) had a higher scavenging potential on the 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH), nitrite oxide (NO), 2, 2-azinobis (3-ethylbenzthiazoline)-6-sulfonic acid (ABTS) radicals and glucose scavenging with the IC50 varied between 41.95 and 36694.43 µg/ml depending on the solvent of extraction. The ethanol extract of C. edulis stem bark (CE EtOH) showed the highest polyphenolic (289.10 + 30.32), flavonoid (1.12 + 0.09) and alkaloids (18.47 + 0.16) content. All the tested extracts demonstrated a relative high inhibition potential against α-amylase and invertase digestive enzymes activities. Conclusion: This study suggests that CEE exhibited higher antioxidant potential and significant inhibition potential against digestive enzymes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Coula%20edulis" title="Coula edulis">Coula edulis</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=scavenging%20activity" title=" scavenging activity"> scavenging activity</a>, <a href="https://publications.waset.org/abstracts/search?q=amylase" title=" amylase"> amylase</a>, <a href="https://publications.waset.org/abstracts/search?q=invertase" title=" invertase"> invertase</a> </p> <a href="https://publications.waset.org/abstracts/65106/free-radical-scavenging-antioxidant-activity-phenolic-alkaloids-contents-and-inhibited-properties-against-a-amylase-and-invertase-enzymes-of-stem-bark-extracts-coula-edulis-b" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65106.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">352</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">516</span> In vitro Control of Mycosphaerella arachidis Deighton the Early Leaf Spot Disease Pathogen of Groundnut by the Extracts from Six Medicinal Plants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Matthew%20Omoniyi%20Adebola">Matthew Omoniyi Adebola</a>, <a href="https://publications.waset.org/abstracts/search?q=Jude%20E%20Amadi"> Jude E Amadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ground nut (Arachis hypogaea) is one of the most popular commercial crops in Nigeria. Its suc-cessful production has been drastically affected by early leaf spot disease caused by Mycosphae-rella arachidis Deighton. In vitro control of the pathogen by six medicinal plants (Entada afri-cana, Vitex doniana, Lawsonia inermis, Azadirachta indica, Acalypha hispida and Nuaclea lati-folia) was assessed in this study. The extracts of the plants were prepared using cold and hot wa-ter and alcohol. The pathogen was isolated from ground nut infected with early leaf spot disease. The results revealed a great significant difference (P<0.05) in yield of extracts between cold water, hot water, and alcohol extracts. A significant difference (P<0.05) was observed in percentage concentrations of the various phytochemical constituents present in the extracts. Flavonoids per-centage concentration was the highest (0.68 - 1.95%) followed by saponnin(0.09-1.53%) in N. latifolia extracts. Steroiods had the least percentage concentrations (0.00- 0.09%)followed by terpenoids(0.02–0.71%) and proanthocyannin (0.05 – 0.86%). N. latifolia extracts produced the highest percentage concentrations (0.07–1.95%) of all the phytochemicals followed by A. indi-ca(0.05–1.64%)and least concentrations were obtained in A. hispidia(0.09 – 0.87%)and V. do-niana (0.00–0.88%). The extracts inhibited spore germination and growth of M. arachidis. The inhibition by alcohol extracts was high and significantly different (P>0.05) from cold and hot water extracts. Alcohol extract of L. inermis gave 100% spore germination inhibition followed by N. latifolia and A.indica with 97.75% and 85.60% inhibition respectively. Therefore, field trials of these six medicinal plants on the control of early leaf spot disease of ground nut are rec-ommended. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=groundnut" title="groundnut">groundnut</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemicals" title=" phytochemicals"> phytochemicals</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=extracts" title=" extracts"> extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=inhibition" title=" inhibition"> inhibition</a> </p> <a href="https://publications.waset.org/abstracts/59666/in-vitro-control-of-mycosphaerella-arachidis-deighton-the-early-leaf-spot-disease-pathogen-of-groundnut-by-the-extracts-from-six-medicinal-plants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59666.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">297</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">515</span> Biophysical Features of Glioma-Derived Extracellular Vesicles as Potential Diagnostic Markers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abhimanyu%20Thakur">Abhimanyu Thakur</a>, <a href="https://publications.waset.org/abstracts/search?q=Youngjin%20Lee"> Youngjin Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glioma is a lethal brain cancer whose early diagnosis and prognosis are limited due to the dearth of a suitable technique for its early detection. Current approaches, including magnetic resonance imaging (MRI), computed tomography (CT), and invasive biopsy for the diagnosis of this lethal disease, hold several limitations, demanding an alternative method. Recently, extracellular vesicles (EVs) have been used in numerous biomarker studies, majorly exosomes and microvesicles (MVs), which are found in most of the cells and biofluids, including blood, cerebrospinal fluid (CSF), and urine. Remarkably, glioma cells (GMs) release a high number of EVs, which are found to cross the blood-brain-barrier (BBB) and impersonate the constituents of parent GMs including protein, and lncRNA; however, biophysical properties of EVs have not been explored yet as a biomarker for glioma. We isolated EVs from cell culture conditioned medium of GMs and regular primary culture, blood, and urine of wild-type (WT)- and glioma mouse models, and characterized by nano tracking analyzer, transmission electron microscopy, immunogold-EM, and differential light scanning. Next, we measured the biophysical parameters of GMs-EVs by using atomic force microscopy. Further, the functional constituents of EVs were examined by FTIR and Raman spectroscopy. Exosomes and MVs-derived from GMs, blood, and urine showed distinction biophysical parameters (roughness, adhesion force, and stiffness) and different from that of regular primary glial cells, WT-blood, and -urine, which can be attributed to the characteristic functional constituents. Therefore, biophysical features can be potential diagnostic biomarkers for glioma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glioma" title="glioma">glioma</a>, <a href="https://publications.waset.org/abstracts/search?q=extracellular%20vesicles" title=" extracellular vesicles"> extracellular vesicles</a>, <a href="https://publications.waset.org/abstracts/search?q=exosomes" title=" exosomes"> exosomes</a>, <a href="https://publications.waset.org/abstracts/search?q=microvesicles" title=" microvesicles"> microvesicles</a>, <a href="https://publications.waset.org/abstracts/search?q=biophysical%20properties" title=" biophysical properties"> biophysical properties</a> </p> <a href="https://publications.waset.org/abstracts/131887/biophysical-features-of-glioma-derived-extracellular-vesicles-as-potential-diagnostic-markers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131887.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">142</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">514</span> Antidiabetic Effect of Methanolic Leaves Extract and Isolated Constituents from Saraca Asoca</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sunil%20Kumar">Sunil Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The present study was performed to investigate the antidiabetic effect of the constituents isolated from Sarca asoca by enzyme inhibitory activity. Methods: The dried leaves of Sarca asoca were defatted with petroleum ether and further the same amount plant materials were extracted with methanol. The dried methanol extract was subjected to fractionation and chromatographic separation, which led to the isolation of kaemferol, β-sitosterol and quercetin stigmasterol. Their structures were elucidated on the basis of spectroscopic studies as well as by comparison with the data available in the literature. The compounds were evaluated for in vitro enzyme inhibition effect. Results: The isolated compounds kaemferol, β-sitosterol and stigmasterol showed 45.32, 40.5 and 41.23% α-amylase inhibition respectively and 43.45, 39.29 and 32.43% α-glucosidase inhibition respectively at the conc. of 50 µg/kg. Conclusion: The compounds isolated from Sarca asoca showed in vitro and in vivo antidiabetic activity. So, Euphorbia hirta is a beneficial plant for management of diabetic disorders. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes" title="diabetes">diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=quercetin" title=" quercetin"> quercetin</a>, <a href="https://publications.waset.org/abstracts/search?q=sitosterol" title=" sitosterol"> sitosterol</a>, <a href="https://publications.waset.org/abstracts/search?q=stigmasterol" title=" stigmasterol"> stigmasterol</a> </p> <a href="https://publications.waset.org/abstracts/30536/antidiabetic-effect-of-methanolic-leaves-extract-and-isolated-constituents-from-saraca-asoca" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30536.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">513</span> Phytochemial Screening, Anti-Microbial and Mineral Determination of Brysocarpus coccineus Root</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20L.%20Ibrahim">I. L. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Mann"> A. Mann</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ndanaimi"> A. Ndanaimi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The research involved phytochemical screening, antibacterial activities and mineral determination by flame photometry of the crude extract of Brysocarpus coccineus schum indeed were carried out. The result of Phytochemical screening reveal tha saponins, alkaloids, cardiac glycosides, and anthraquinones were present. This suggests that the plant extract could be used as anti-inflammatory and anti-bleeding agents. Estimation of mineral content shows that the crude extract of B. coccineus contains 0.73 (Na+), 1.06 (K+) and 1.98 (Ca+) which justifies its use to be safe for hypertensive patients and could be used to lower blood pressure. The antibacterial properties of aqueous and ethanol extract were studied against some bacteria; pseudomonas aeruginosa, Escherichia coli, Bacilus subtilis, Klebsilla penmuoniae by disc diffusion method. The aqueous extract showed significant activity against the organisms while the ethanol at concentrations 5-10mg/ml ethanol extract showed significant zone of inhibition against the organisms, E. coli, (19 mm), B. cereus (12 mm), P. aeruginosa (11 mm), K. pnemuoniae (11 mm). Minimum inhibitory concentration (MIC) was carried with considerable effect of inhibition on the organisms. The MIC values observed were 1, 24, 16 and 19 mm against E. coli, B. cereus, P. aeruginosa and K. pnemuoniae respectively. Therefore, the plant could be a potential source of antibacterial agent although more pharmacological and clinical study may be recommended. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phytochemicals" title="phytochemicals">phytochemicals</a>, <a href="https://publications.waset.org/abstracts/search?q=microorganisms" title=" microorganisms"> microorganisms</a>, <a href="https://publications.waset.org/abstracts/search?q=screenings" title=" screenings"> screenings</a>, <a href="https://publications.waset.org/abstracts/search?q=mineral%20ions" title=" mineral ions"> mineral ions</a> </p> <a href="https://publications.waset.org/abstracts/38304/phytochemial-screening-anti-microbial-and-mineral-determination-of-brysocarpus-coccineus-root" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/38304.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light 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