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Impact of COVID-19 on Cardiovascular and Diabetic Patients – Vaccine Studies
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id="primary"> <main class="site-main" id="main"> <article id="post-48" class="post-48 post type-post status-publish format-standard has-post-thumbnail hentry category-cardiovascular-disease tag-cardiovascular-disease tag-chronic-conditions tag-covid-19 tag-cytokine-storm tag-diabetes tag-glycemic-control tag-healthcare-management tag-hyperglycemia tag-preventive-measures tag-telemedicine" itemtype="https://schema.org/CreativeWork" itemscope> <div class="inside-article"> <div class="featured-image page-header-image-single "> <img width="1200" height="628" src="https://vaccine-studies.com/archive/wp-content/uploads/2024/09/Cardiovascular-and-Diabetic-Patients-15-1-min-scaled-e1725644596385.jpg" class="attachment-full size-full" alt="" itemprop="image" decoding="async" fetchpriority="high" /> </div> <header class="entry-header"> <h1 class="entry-title" itemprop="headline">Impact of COVID-19 on Cardiovascular and Diabetic Patients</h1> <div class="entry-meta"> <span class="posted-on"><time class="updated" datetime="2024-09-06T23:13:24+05:30" itemprop="dateModified">September 6, 2024</time><time class="entry-date published" datetime="2024-09-02T10:43:19+05:30" itemprop="datePublished">September 2, 2024</time></span> <span class="byline">by <span class="author vcard" itemprop="author" itemtype="https://schema.org/Person" itemscope><a class="url fn n" href="https://vaccine-studies.com/archive/author/vaccine-studies/" title="View all posts by vaccine-studies" rel="author" itemprop="url"><span class="author-name" itemprop="name">vaccine-studies</span></a></span></span> </div> </header> <div class="entry-content" itemprop="text"> <p><span style="font-weight: 400;">COVID-19 has impacted the world’s health systems in ways that have not been seen before, with deaths and infections affecting millions of people in the world today. The virus is especially dangerous for the most vulnerable groups of the population, for instance, patients with CVD and diabetes. Not only do these persons need to understand their susceptibility to more severe forms should they be infected by the SARS-CoV-2 virus, which is responsible for COVID-19, but they also have to be aware of the fact that their conditions present specific treatment challenges. Knowledge of COVID-19’s effects and its interactions with these chronic illnesses is vital in caring for the patients and in catering for the impacts on available healthcare resources during the pandemic.</span></p> <p><span style="font-weight: 400;">COVID-19 is a serious threat to patients with cardiovascular disease. This infection can also make pre-existing heart conditions worse to the point of heart failure, arrhythmias, and acute coronary syndromes. People with pre-existing heart issues are more vulnerable to poor evolution based on how the virus increases inflammation in the heart. This inflammation can result in the rupture of the plaques, and this makes people suffer heart attacks and other cardiovascular complications. Also, COVID-19 can exert a direct impact on the respiratory system, resulting in pulmonary hypertension, which puts more pressure on the heart, especially for patients with pre-existing cardiovascular disorders.</span></p> <p><span style="font-weight: 400;">Likewise, COVID-19 impacts those having diabetes in dreadful ways; they form a vulnerable population during the pandemic. Diabetes can affect the immune system of a person to some extent; therefore, the body may not be very strong enough to fight off infections such as COVID-19. Also, high blood sugar affects inflammation processes and, if infected, can lead to more serious complications. Also, diabetic patients have other related illnesses like obesity, hypertension, and cardiovascular disease, which elevates the chances of critical illness and death caused by COVID-19. Diabetic patients who get infected with COVID-19 have to be closely monitored before and during management to ensure good glycemic control and proceed with appropriate management of any complications.</span></p> <p><span style="font-weight: 400;">A new study record reveals that people with both CVD and diabetes are at a much higher risk of hospitalization, ICU admission, and death if infected with COVID-19. These observations signify that more effective approaches to the allocation and utilization of resources concerning these identified populations are vital and urgent. Patient compliance with prescribed drugs means good management of clients, including maintaining near-normal blood sugar and blood pressure levels, preventing diseases by getting vaccinated, and washing hands frequently.</span></p> <p><span style="font-weight: 400;">COVID-19 and cardiovascular disease can coexist and affect each other in various ways. COVID-19 is proprioceptively linked with the ACE2 receptor, which is also used by the virus to invade human cells and at the same time control blood pressure and cardiovascular functions. SARS-CoV-2 uses this receptor to enter cells; this interferes with usual cardiovascular processes and causes complications. For instance, the direct viral tropism for ACE2 causes unopposed intravascular angiotensin II activity, leading to constriction, inflammation, and oxidative stress, all of which are cardiotoxic.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Yearwise Publication Trend on <b>“<a href="https://vaccine-studies.com/publication-trends/index/cardiovascular disease" target="_blank" title="cardiovascular disease - yearwise publication trends">cardiovascular disease</a>”</b></h2> </div> </div><div class="results-container"><div class="chart-block" style="padding:15px;"> <div class="left"> <div id="results" class="results"></div> </div> <div class="right"> <div class="chart-container"><canvas id="publicationChart"></canvas></div> </div> <div class="keywordsdiv"> <div style="text-align:center;"><b>Find publication trends on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-stats"></span> </div> </div></div></div><div class="inside-article"><style> table { margin: 0 0 1.5em; 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if (!statistics || Object.keys(statistics).length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var tableHTML = `<div class='pub-scroll'> <table class='tablediv' border='1' cellspacing='0' cellpadding='0'> <tr> <th>Year</th> <th>Publication Count</th> </tr>`; Object.entries(statistics).sort(([yearA], [yearB]) => yearB - yearA).forEach(([year, count]) => { const displayCount = count === 0 ? 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COVID-19 can cause acute decompensated heart failure, where the patient becomes extremely unwell and needs to see a doctor urgently. A cytokine storm provoked by the virus entails elevated levels of pro-inflammatory cytokines that can worsen the condition of heart failure and cause critical states. Also, COVID-19 deteriorates the patient’s coagulation status, which leads to the formation of blood clots and blocks of some organs, for example, thromboembolism or stroke, dangerous in patients with prior cardiovascular diseases.</span></p> <p><span style="font-weight: 400;">This situation makes winding up the COVID-19 complications even more severe for diabetic patients due to other metabolic complications they may be facing. High blood sugar levels such as those seen in diabetes can weaken immune systems and consequently make the body more vulnerable to infections. Further, in the context of an inflammation state linked to diabetes, the</span></p> <p><span style="font-weight: 400;">severity of COVID-19 can become even worse. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are two severe metabolic complications that appear in diabetic patients with COVID-19, for which early management would be essential due to high mortality.</span></p> <p><span style="font-weight: 400;">The strategy of dealing with COVID-19 cases in patients with diabetes is not a one-size-fits-all approach. It is also crucial to maintain proper glycemic levels; in a case where diabetes is present, it is associated with a poor prognosis. Diabetes patients should be encouraged to check their blood glucose levels regularly and modify their medications with the doctor’s help. Furthermore, concerning patients with T2DM, healthcare providers should monitor the development of DKA and HHS and act accordingly when possible.</span></p> <p><span style="font-weight: 400;">As part of the REPROGRAM consortium, researchers have pointed out that such patient groups require specific intervention approaches during the COVID-19 pandemic. Such strategies include the restructuring of the health care systems to ensure continuity of care to patients with chronic diseases in case of lockdowns or congestion of the health care centers. </span><span style="font-weight: 400;">Telemedicine has thus become very useful in such a situation as it enables monitoring and consultation from the comfort of clients’ homes, thus minimizing their exposure to the virus.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Recent Publications on <b>“<a href="https://vaccine-studies.com/recent-publications/index/cardiovascular disease" target="_blank" rel="noopener" title="cardiovascular disease - yearwise publication list">cardiovascular disease</a>”</b></h2> </div> </div> <div class="pb-main"><div class="article-scroll"><div id="results_recent" class="results"></div></div><div class="keywordsdiv" style="margin: 0px 15px;margin-top:20px;"> <div style="text-align:center;"><b>Find publications on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-papers"></span> </div></div></div><div class="inside-article"> <style> .pb-main{ border: solid 1px #ccc; 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A retrospective analysis of six regions in Europe.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946449", "publishedDate": "2024" }, { "title": "Egg white-derived peptides reduced blood glucose in high-fat-diet and low-dose streptozotocin-induced type 2 diabetic mice regulating the hepatic gluconeogenic signaling and metabolic profile.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38855929", "publishedDate": "2024" }, { "title": "Cardiovascular complications in the course of COVID-19 - lessons learned and implications for the future care of patients with viral respiratory diseases: Data from a single center retrospective observational study.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38944910", "publishedDate": "2024" }, { "title": "Computed tomography angiography and coronary artery disease-reporting and data system and a 5-year prognostic major adverse cardiovascular and cerebral event outcome study in a symptomatic Southeast Asian population.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946395", "publishedDate": "2024" }, { "title": "Cardiovascular disease burden in patients with urological cancers: The new discipline of uro-cardio-oncology.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946935", "publishedDate": "2024" }, { "title": "Predicting cerebrovascular age and its clinical relevance: Modeling using 3D morphological features of brain vessels.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947444", "publishedDate": "2024" }, { "title": "In utero chronic intermittent nicotine aerosol exposure increases ischemic heart injury in adult offspring via programming of Angiotensin II receptor-derived TGF\u03b2\/ROS\/Akt signaling pathway.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945500", "publishedDate": "2024" }, { "title": "Chronic Kidney Disease Study in Diabetic Patients: Insights From Primary Care Units in Northern Portugal.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947587", "publishedDate": "2024" }, { "title": "Evaluating Cardiovascular Risks: The Platelet Lymphocyte Ratio and the Neutrophil Lymphocyte Ratio As High-Risk Heart Score Predictors in Non-ST Elevation Myocardial Infarction (NSTEMI) and Unstable Angina Patients.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947629", "publishedDate": "2024" }, { "title": "Cardio-oncology in advanced prostate cancer.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947889", "publishedDate": "2024" }, { "title": "Integrating network pharmacology and animal experimental validation to investigate the action mechanism of oleanolic acid in obesity.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38246999", "publishedDate": "2024" }, { "title": "Obesity and risk of diseases associated with hallmarks of cellular ageing: a multicohort study.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945128", "publishedDate": "2024" }, { "title": "The signaling pathways in obesity-related complications.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946722", "publishedDate": "2024" }, { "title": "NLRP3 inflammasome: a key player in the pathogenesis of life-style disorders.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945951", "publishedDate": "2024" }, { "title": "The athero-contour: A novel tool for global and rapid assessment of atherogenic parameters. A use case in saroglitazar treatment of MAFLD patients.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945785", "publishedDate": "2024" }, { "title": "Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945954", "publishedDate": "2024" }, { "title": "Digital twins: reimagining the future of cardiovascular risk prediction and personalised care.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38852883", "publishedDate": "2024" }, { "title": "Wearable device-measured moderate to vigorous physical activity and risk of degenerative aortic valve stenosis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38953786", "publishedDate": "2024" }, { "title": "Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38953911", "publishedDate": "2024" } ]; var keywordsArray = ["COVID-19","Cardiovascular Disease","Diabetes","Chronic Conditions","Healthcare Management","Telemedicine","Preventive Measures","Glycemic Control","Hyperglycemia","Cytokine Storm"]; displayResults_recent(recent_papers); displayKeywordPapers(keywordsArray); // function stripslashes(str) { // if (typeof str === 'string') { // return str.replace(/\/g, ''); // } // } </script></p> <p><span style="font-weight: 400;">The more vulnerable patients are also at risk of contracting the disease; therefore, preventive measures are important. Immunization against COVID-19 is advised for persons who have cardiovascular disease and diabetes. Such patients should also ensure they observe the preventive measures as recommended by the authorities, which include wearing masks, observing social distancing, and washing hands frequently. Thus, in addition to the protection of oneself and family members, society as a whole must limit contact with high-risk groups and adhere to the instructions given by public health officials to prevent the spread of the virus.</span></p> <p><span style="font-weight: 400;">Therefore, COVID-19 poses a severe risk to patients with cardiovascular diseases and diabetes; thus, care should be extensive and preemptive for patients with these conditions. Awareness of the particular characteristics observed in the identified populations may help design corresponding intervention measures to optimize patient care and improve the results in these cases. In future utilization of these examined strategies as well as in the search for other suitable interventions, future research and practice will be imperative as the pandemic persists to ensure optimal care for at-risk populations.</span></p> <p></p> <p><b>References</b></p> <ol> <li>Rahman J, Muralidharan A, Quazi SJ, Saleem H, Khan S. <a href="https://pubmed.ncbi.nlm.nih.gov/32528783/">Neurological and Psychological Effects of Coronavirus (COVID-19): An Overview of the Current Era Pandemic.</a> Cureus. 2020 Jun 5;12(6):e8460. doi: 10.7759/cureus.8460. PMID: 32528783; PMCID: PMC7282368.</li> <li>Li YC, Bai WZ, Hashikawa T. <a href="https://pubmed.ncbi.nlm.nih.gov/32104915/">The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients.</a> J Med Virol. 2020 Jun;92(6):552-555. doi: 10.1002/jmv.25728. Epub 2020 Mar 11. PMID: 32104915; PMCID: PMC7228394.</li> <li>Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, Hu B. <a href="https://pubmed.ncbi.nlm.nih.gov/32275288/">Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China</a>. JAMA Neurol. 2020 Jun 1;77(6):683-690. doi: 10.1001/jamaneurol.2020.1127. PMID: 32275288; PMCID: PMC7149362.</li> <li>Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O, Graham BS, McLellan JS. <a href="https://pubmed.ncbi.nlm.nih.gov/32075877/">Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.</a> Science. 2020 Mar 13;367(6483):1260-1263. doi: 10.1126/science.abb2507. Epub 2020 Feb 19. PMID: 32075877; PMCID: PMC7164637.</li> <li>Bhaskar S, Rastogi A, Chattu VK, Adisesh A, Thomas P, Alvarado N, Riahi AD, Varun CN, Pai AR, Barsam S, Walker AH. <a href="https://pubmed.ncbi.nlm.nih.gov/32613010/">Key Strategies for Clinical Management and Improvement of Healthcare Services for Cardiovascular Disease and Diabetes Patients in the Coronavirus (COVID-19) Settings: Recommendations From the REPROGRAM Consortium.</a> Front Cardiovasc Med. 2020 Jun 16;7:112. doi: 10.3389/fcvm.2020.00112. PMID: 32613010; PMCID: PMC7308556.</li> <li>Verma S, Dhanak M, Frankenfield J. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327717/">Visualizing the effectiveness of face masks in obstructing respiratory jets.</a> Phys Fluids (1994). 2020 Jun 1;32(6):061708. doi: 10.1063/5.0016018. 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PMID: 31259864.</li> </ol> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Top Experts on “<b style="color:#000;font-size:22px;">cardiovascular disease</b>“</h2> </div> </div><div class="author-main"><div id="results_author"></div><div style="text-align: center;"><a class="register-button" href="https://vaccine-studies.com/expert-search" target="_blank" rel="noopener">Find experts on any field</a></div></div><div class="inside-article" style="background: none;border: none;box-shadow: none;margin-top: -70px;"> <style> .author-block { padding: 15px; margin-bottom: 10px; text-align: left; font-size: 15px; line-height: 1.2; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .author-block h3 { margin: 0 0 10px; color: #227cdc; } .author-block p { margin: 5px 0; } .author-b { display: flex; justify-content: space-between; flex-wrap: wrap; margin-bottom:10px; } .author-b .ainfo { flex: 1 1 30%; box-sizing: border-box; text-align: left; background: #dcdcdc; padding: 7px 14px; border-radius: 5px; margin-top: 3px; margin-right: 10px; } @media (max-width: 768px) { .author-b .ainfo { flex: 1 1 100%; margin: 10px 0; } } </style> <script> function displayResults_author(authors) { var resultsContainer = document.getElementById('results_author'); resultsContainer.innerHTML = ''; if (!authors || Object.keys(authors).length === 0) { resultsContainer.innerHTML = '<p>No authors found.</p>'; return; } Object.values(authors).slice(0, 10).forEach(author => { if (author.affiliation.length > 400) { return; } var authorBlock = document.createElement('div'); authorBlock.className = 'author-block'; var author_name=author.name; let key_replace = author_name.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); var authorHTML = ` <h3><a href="https://vaccine-studies.com/author/index/${key_replace}\/${author.aid}" target="_blank" title="${author.name}">${author.name}</a></h3> <div class="author-b"> <div class="ainfo"><strong>H-Index:</strong> ${author.hindex}</div> <div class="ainfo"><strong>Publication Count:</strong> ${author.paper_count}</div> <div class="ainfo"><strong>Citation Count:</strong> ${author.citation_count}</div> </div> <p><strong>Affiliation:</strong> ${author.affiliation}</p> `; authorBlock.innerHTML = authorHTML; resultsContainer.appendChild(authorBlock); }); } function displayKeywordAuthors(keywords) { var resultsContainer = document.getElementById('keyword-authors'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach(key => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://vaccine-studies.com/expert-search/index/${key_replace}" target="_blank" title="${key}">${key}</a>`; }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var authors_data = { "NbpaK4wBWBy50K-rgWuP": { "aid": "NbpaK4wBWBy50K-rgWuP", "name": "M. 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