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id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&returnto=%E4%B9%B3%E6%B8%85%E9%85%B8" title="我们推荐您创建账号并登录，但这不是强制性的"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>创建账号</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&returnto=%E4%B9%B3%E6%B8%85%E9%85%B8" title="建议你登录，尽管并非必须。[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>登录</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> 未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%B4%A1%E7%8C%AE" title="来自此IP地址的编辑列表[y]" accesskey="y"><span>贡献</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%AE%A8%E8%AE%BA%E9%A1%B5" title="对于来自此IP地址编辑的讨论[n]" accesskey="n"><span>讨论</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="站点"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目录" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">序言</div> </a> </li> <li id="toc-合成" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#合成"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>合成</span> </div> </a> <ul id="toc-合成-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-安全性" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#安全性"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>安全性</span> </div> </a> <ul id="toc-安全性-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-病理學" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#病理學"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>病理學</span> </div> </a> <ul id="toc-病理學-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參見" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參見"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>參見</span> </div> </a> <ul id="toc-參見-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參考文獻" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參考文獻"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>參考文獻</span> </div> </a> <ul id="toc-參考文獻-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部連結" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部連結"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>外部連結</span> </div> </a> <ul id="toc-外部連結-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">乳清酸</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。26种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-26" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">26种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A7%D9%88%D8%B1%D9%88%D8%AA%DB%8C%DA%A9_%D8%A7%D8%B3%DB%8C%D8%AF" title="اوروتیک اسید – South Azerbaijani" lang="azb" hreflang="azb" data-title="اوروتیک اسید" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9E%D1%80%D0%BE%D1%82%D0%BE%D0%B2%D0%B0_%D0%BA%D0%B8%D1%81%D0%B5%D0%BB%D0%B8%D0%BD%D0%B0" title="Оротова киселина – 保加利亚语" lang="bg" hreflang="bg" data-title="Оротова киселина" data-language-autonym="Български" data-language-local-name="保加利亚语" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/%C3%80cid_or%C3%B2tic" title="Àcid oròtic – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Àcid oròtic" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Orots%C3%A4ure" title="Orotsäure – 德语" lang="de" hreflang="de" data-title="Orotsäure" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Orotic_acid" title="Orotic acid – 英语" lang="en" hreflang="en" data-title="Orotic acid" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/%C3%81cido_or%C3%B3tico" title="Ácido orótico – 西班牙语" lang="es" hreflang="es" data-title="Ácido orótico" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/B13-vitamiin" title="B13-vitamiin – 爱沙尼亚语" lang="et" hreflang="et" data-title="B13-vitamiin" data-language-autonym="Eesti" data-language-local-name="爱沙尼亚语" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D9%88%D8%B1%D9%88%D8%AA%DB%8C%DA%A9_%D8%A7%D8%B3%DB%8C%D8%AF" title="اوروتیک اسید – 波斯语" lang="fa" hreflang="fa" data-title="اوروتیک اسید" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Oroottihappo" title="Oroottihappo – 芬兰语" lang="fi" hreflang="fi" data-title="Oroottihappo" data-language-autonym="Suomi" data-language-local-name="芬兰语" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Acide_orotique" title="Acide orotique – 法语" lang="fr" hreflang="fr" data-title="Acide orotique" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%93%E0%A4%B0%E0%A5%8B%E0%A4%9F%E0%A4%BF%E0%A4%95_%E0%A4%85%E0%A4%AE%E0%A5%8D%E0%A4%B2" title="ओरोटिक अम्ल – 印地语" lang="hi" hreflang="hi" data-title="ओरोटिक अम्ल" data-language-autonym="हिन्दी" data-language-local-name="印地语" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Orotsav" title="Orotsav – 匈牙利语" lang="hu" hreflang="hu" data-title="Orotsav" data-language-autonym="Magyar" data-language-local-name="匈牙利语" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Asam_orotat" title="Asam orotat – 印度尼西亚语" lang="id" hreflang="id" data-title="Asam orotat" data-language-autonym="Bahasa Indonesia" data-language-local-name="印度尼西亚语" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Acido_orotico" title="Acido orotico – 意大利语" lang="it" hreflang="it" data-title="Acido orotico" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%AA%E3%83%AD%E3%83%88%E9%85%B8" title="オロト酸 – 日语" lang="ja" hreflang="ja" data-title="オロト酸" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%92%E0%B2%B0%E0%B2%BE%E0%B2%9F%E0%B2%BF%E0%B2%95%E0%B3%8D_%E0%B2%86%E0%B2%AE%E0%B3%8D%E0%B2%B2" title="ಒರಾಟಿಕ್ ಆಮ್ಲ – 卡纳达语" lang="kn" hreflang="kn" data-title="ಒರಾಟಿಕ್ ಆಮ್ಲ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="卡纳达语" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%98%A4%EB%A1%9C%ED%8A%B8%EC%82%B0" title="오로트산 – 韩语" lang="ko" hreflang="ko" data-title="오로트산" data-language-autonym="한국어" data-language-local-name="韩语" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Orootzuur" title="Orootzuur – 荷兰语" lang="nl" hreflang="nl" data-title="Orootzuur" data-language-autonym="Nederlands" data-language-local-name="荷兰语" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Kwas_orotowy" title="Kwas orotowy – 波兰语" lang="pl" hreflang="pl" data-title="Kwas orotowy" data-language-autonym="Polski" data-language-local-name="波兰语" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/%C3%81cido_or%C3%B3tico" title="Ácido orótico – 葡萄牙语" lang="pt" hreflang="pt" data-title="Ácido orótico" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9E%D1%80%D0%BE%D1%82%D0%BE%D0%B2%D0%B0%D1%8F_%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D0%B0" title="Оротовая кислота – 俄语" lang="ru" hreflang="ru" data-title="Оротовая кислота" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Oroti%C4%8Dna_kiselina" title="Orotična kiselina – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Orotična kiselina" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Kyselina_orotov%C3%A1" title="Kyselina orotová – 斯洛伐克语" lang="sk" hreflang="sk" data-title="Kyselina orotová" data-language-autonym="Slovenčina" data-language-local-name="斯洛伐克语" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Oroti%C4%8Dna_kiselina" title="Orotična kiselina – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Orotična kiselina" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Orotsyra" title="Orotsyra – 瑞典语" lang="sv" hreflang="sv" data-title="Orotsyra" data-language-autonym="Svenska" data-language-local-name="瑞典语" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9E%D1%80%D0%BE%D1%82%D0%BE%D0%B2%D0%B0_%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D0%B0" title="Оротова кислота – 乌克兰语" lang="uk" hreflang="uk" data-title="Оротова кислота" data-language-autonym="Українська" data-language-local-name="乌克兰语" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q425536#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> 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vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">外观</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">隐藏</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">维基百科，自由的百科全书</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="zh" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r83732082">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="國際非專利藥名（INN）：乳清酸">乳清酸</span></caption><tbody><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><a href="/wiki/File:Orotic_acid.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Orotic_acid.svg/150px-Orotic_acid.svg.png" decoding="async" width="150" height="151" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Orotic_acid.svg/225px-Orotic_acid.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/77/Orotic_acid.svg/300px-Orotic_acid.svg.png 2x" data-file-width="745" data-file-height="750" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">臨床資料</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%BE%8E%E5%9C%8B%E8%A1%9B%E7%94%9F%E7%B3%BB%E7%B5%B1%E8%97%A5%E5%B8%AB%E5%8D%94%E6%9C%83" title="美國衛生系統藥師協會">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data" style=""><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/orotic-acid.html">国际药品名称</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%A7%A3%E5%89%96%E5%AD%A6%E6%B2%BB%E7%96%97%E5%AD%A6%E5%8F%8A%E5%8C%96%E5%AD%A6%E5%88%86%E7%B1%BB%E7%B3%BB%E7%BB%9F" title="解剖学治疗学及化学分类系统">ATC碼</a></th><td class="infobox-data" style=""><style data-mw-deduplicate="TemplateStyles:r82655520">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li>未分配</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">识别信息</th></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC命名法</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid</div></li><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;"></div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/CAS%E5%8F%B7" title="CAS号">CAS号</a></th><td class="infobox-data" style=""><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=65-86-1">65-86-1</a></span> <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/967">967</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB02262">DB02262</a></span><sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.942.html">942</a></span><sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%89%B9%E6%AE%8A%E6%88%90%E5%88%86%E6%A8%99%E8%AD%98" title="特殊成分標識">UNII</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/61H4T033E5">61H4T033E5</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/C00295">C00295</a></span><sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><span class="ilh-all" data-orig-title="CompTox化学品仪表板" data-lang-code="en" data-lang-name="英语" data-foreign-title="CompTox Chemicals Dashboard"><span class="ilh-page"><a href="/w/index.php?title=CompTox%E5%8C%96%E5%AD%A6%E5%93%81%E4%BB%AA%E8%A1%A8%E6%9D%BF&action=edit&redlink=1" class="new" title="CompTox化学品仪表板（页面不存在）">CompTox Dashboard</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/CompTox_Chemicals_Dashboard" class="extiw" title="en:CompTox Chemicals Dashboard"><span lang="en" dir="auto">CompTox Chemicals Dashboard</span></a></span>）</span></span> <span style="font-weight:normal">(<abbr title="美国国家环境保护局">EPA</abbr>)</span></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID0025814">DTXSID0025814</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q425536#P3117" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%AD%90%E6%B4%B2%E5%8C%96%E5%AD%B8%E5%93%81%E7%AE%A1%E7%90%86%E5%B1%80" title="歐洲化學品管理局"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.000.563">100.000.563</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q425536#P2566" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">化学信息</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a></th><td class="infobox-data" style=""><span title="Carbon">C</span><sub>5</sub><span title="Hydrogen">H</span><sub>4</sub><span title="Nitrogen">N</span><sub>2</sub><span title="Oxygen">O</span><sub>4</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%91%A9%E5%B0%94%E8%B4%A8%E9%87%8F" title="摩尔质量">摩尔质量</a></th><td class="infobox-data" style="">156.10 g/mol</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;">3D模型（<span class="ilh-all" data-orig-title="JSmol" data-lang-code="en" data-lang-name="英语" data-foreign-title="JSmol"><span class="ilh-page"><a href="/w/index.php?title=JSmol&action=edit&redlink=1" class="new" title="JSmol（页面不存在）">JSmol</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/JSmol" class="extiw" title="en:JSmol"><span lang="en" dir="auto">JSmol</span></a></span>）</span></span>）</th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=O%3DC%28O%29%5CC1%3DC%5CC%28%3DO%29NC%28%3DO%29N1">交互式图像</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E7%AE%80%E5%8C%96%E5%88%86%E5%AD%90%E7%BA%BF%E6%80%A7%E8%BE%93%E5%85%A5%E8%A7%84%E8%8C%83" title="简化分子线性输入规范">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">O=C(O)\C1=C\C(=O)NC(=O)N1</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)<sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:PXQPEWDEAKTCGB-UHFFFAOYSA-N<sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></div></li></ul> </div></td></tr></tbody></table> <p><b>乳清酸</b>（英語：<span lang="en"><b>Orotic acid</b></span>，<a href="/wiki/%E5%85%B1%E8%BB%9B%E9%B9%BC" class="mw-redirect" title="共軛鹼">共軛鹼</a>作<span lang="en"><b>orotate</b></span>）或<b>嘧啶酸</b>（<b><span lang="en">pyrimidinecarboxylic acid</span></b>）是一種<a href="/wiki/%E9%9B%9C%E7%92%B0%E5%8C%96%E5%90%88%E7%89%A9" class="mw-redirect" title="雜環化合物">雜環化合物</a>，也是一種有機酸。乳清酸曾經被誤以為是一種<a href="/wiki/%E7%B6%AD%E7%94%9F%E7%B4%A0B" class="mw-redirect" title="維生素B">維生素B</a>，並被稱為<b><span lang="en">vitamin B<sub>13</sub></span></b>，但後來發現他並不屬於維生素。 </p><p>此化合物是由<a href="/wiki/%E7%B2%92%E7%B7%9A%E9%AB%94" class="mw-redirect" title="粒線體">粒線體</a>的一種酵素－<a href="/wiki/%E4%BA%8C%E6%B0%AB%E4%B9%B3%E6%B8%85%E9%85%B8%E8%84%AB%E6%B0%AB%E9%85%B6" title="二氫乳清酸脫氫酶">二氫乳清酸脫氫酶</a><sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>或細胞質中的<span class="ilh-all" data-orig-title="Pyrimidine metabolism" data-lang-code="en" data-lang-name="英语" data-foreign-title="Pyrimidine metabolism"><span class="ilh-page"><a href="/w/index.php?title=Pyrimidine_metabolism&action=edit&redlink=1" class="new" title="Pyrimidine metabolism（页面不存在）">嘧啶合成途徑</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Pyrimidine_metabolism" class="extiw" title="en:Pyrimidine metabolism"><span lang="en" dir="auto">Pyrimidine metabolism</span></a></span>）</span></span>的酵素所合成。有時此化合物會被用做<a href="/wiki/%E4%B9%B3%E8%A3%BD%E5%93%81" class="mw-redirect" title="乳製品">乳製品</a>的<span class="ilh-all" data-orig-title="mineral carrier" data-lang-code="en" data-lang-name="英语" data-foreign-title="mineral carrier"><span class="ilh-page"><a href="/w/index.php?title=Mineral_carrier&action=edit&redlink=1" class="new" title="Mineral carrier（页面不存在）">礦物質攜帶者</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/mineral_carrier" class="extiw" title="en:mineral carrier"><span lang="en" dir="auto">mineral carrier</span></a></span>）</span></span>，如乳清酸鋰。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="合成"><span id=".E5.90.88.E6.88.90"></span>合成</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=1" title="编辑章节：合成"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>乳清酸可藉由酶將<a href="/wiki/4,5-%E4%BA%8C%E6%B0%A2%E4%B9%B3%E6%B8%85%E9%85%B8" title="4,5-二氢乳清酸">二氫乳清酸</a>脫氫形成，之後會與<a href="/wiki/%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96%E7%84%A6%E7%A3%B7%E9%85%B8" title="磷酸核糖焦磷酸">5'-磷酸核糖焦磷酸</a>（PRPP）結合形成<a href="/wiki/%E4%B9%B3%E6%B8%85%E8%8B%B7-5%27-%E7%A3%B7%E9%85%B8" title="乳清苷-5'-磷酸">乳清苷-5'-磷酸</a>（OMP）。在此時與<a href="/wiki/%E5%98%8C%E5%91%A4%E4%BB%A3%E8%B0%A2#生物合成" title="嘌呤代谢">嘌呤合成</a>的不同點是在與<a href="/wiki/%E6%A0%B8%E7%B3%96" title="核糖">核糖</a>相接前，嘧啶環已經完全合成；而嘌呤合成則是將核糖上的鹼基一步一步轉換成嘌呤<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="安全性"><span id=".E5.AE.89.E5.85.A8.E6.80.A7"></span>安全性</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=2" title="编辑章节：安全性"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>乳清酸為<a href="/wiki/%E5%93%BA%E4%B9%B3%E9%A1%9E" class="mw-redirect" title="哺乳類">哺乳類</a>體細胞的<a href="/wiki/%E7%AA%81%E8%AE%8A%E5%8E%9F" title="突變原">突變原</a>，同時也可誘變細菌及酵母菌<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="病理學"><span id=".E7.97.85.E7.90.86.E5.AD.B8"></span>病理學</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=3" title="编辑章节：病理學"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>尿中出現乳清酸可能會導致<span class="ilh-all" data-orig-title="orotic aciduria" data-lang-code="en" data-lang-name="英语" data-foreign-title="orotic aciduria"><span class="ilh-page"><a href="/w/index.php?title=Orotic_aciduria&action=edit&redlink=1" class="new" title="Orotic aciduria（页面不存在）">乳清酸尿症</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/orotic_aciduria" class="extiw" title="en:orotic aciduria"><span lang="en" dir="auto">orotic aciduria</span></a></span>）</span></span>以及<a href="/wiki/%E9%85%B8%E8%A1%80%E7%97%87" class="mw-redirect" title="酸血症">酸血症</a>。病因可能是<a href="/wiki/Metabolic_disorder" class="mw-redirect" title="Metabolic disorder">遗传性代谢缺陷</a>（如<a href="/wiki/Urea_cycle_disorder" class="mw-redirect" title="Urea cycle disorder">尿素循環缺失症</a>）導致血液中<a href="/wiki/Ammonia" class="mw-redirect" title="Ammonia">氨</a>含量過高。 </p><p><br /> </p><p>有一種X染色體關聯<a href="/wiki/%E6%80%A7%E8%81%94%E9%81%97%E4%BC%A0" class="mw-redirect" title="性联遗传">性聯遺傳</a>疾病，稱為<span class="ilh-all" data-orig-title="ornithine transcarbamoylase deficiency" data-lang-code="en" data-lang-name="英语" data-foreign-title="ornithine transcarbamoylase deficiency"><span class="ilh-page"><a href="/w/index.php?title=Ornithine_transcarbamoylase_deficiency&action=edit&redlink=1" class="new" title="Ornithine transcarbamoylase deficiency（页面不存在）">鳥胺酸氨甲醯基轉移酶缺乏症</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/ornithine_transcarbamoylase_deficiency" class="extiw" title="en:ornithine transcarbamoylase deficiency"><span lang="en" dir="auto">ornithine transcarbamoylase deficiency</span></a></span>）</span></span>，是一種最常見的尿素循環缺失症。此疾病會導致細胞中的<a href="/w/index.php?title=%E6%B0%A8%E7%94%B2%E9%85%B0%E7%A3%B7%E9%85%B8&action=edit&redlink=1" class="new" title="氨甲酰磷酸（页面不存在）">氨甲酰磷酸</a>轉化為乳清酸，導致血漿中氨含量過高，尿中乳清酸含量增加，血漿<a href="/wiki/Blood_urea_nitrogen" class="mw-redirect" title="Blood urea nitrogen">尿素氮</a>含量降低。高血氨會導致血漿中的<a href="/wiki/%CE%91-%E9%85%AE%E6%88%8A%E4%BA%8C%E9%85%B8" title="Α-酮戊二酸">α-酮戊二酸</a>含量下降，抑制<a href="/wiki/%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%8E%AF" title="三羧酸循环">三羧酸循环</a>及<a href="/wiki/%E4%B8%89%E7%A3%B7%E9%85%B8%E8%85%BA%E8%8B%B7" title="三磷酸腺苷">ATP</a>產生。 </p> <div class="mw-heading mw-heading2"><h2 id="參見"><span id=".E5.8F.83.E8.A6.8B"></span>參見</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=4" title="编辑章节：參見"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/%E5%90%8D%E7%A7%B0%E7%8B%AC%E7%89%B9%E7%9A%84%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E5%88%97%E8%A1%A8" title="名称独特的化学物质列表">名稱獨特的化學物質列表</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="參考文獻"><span id=".E5.8F.83.E8.80.83.E6.96.87.E7.8D.BB"></span>參考文獻</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=5" title="编辑章节：參考文獻"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><cite class="citation journal">Rawls, J; Knecht, W; Diekert, K; Lill, R; Löffler, M. Requirements for the mitochondrial import and localization of dihydroorotate dehydrogenase. European journal of biochemistry / FEBS. 2000, <b>267</b> (7): 2079–87. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/10727948"><span title="公共医学识别码">PMID 10727948</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E4%B9%B3%E6%B8%85%E9%85%B8&rft.atitle=Requirements+for+the+mitochondrial+import+and+localization+of+dihydroorotate+dehydrogenase&rft.au=Diekert%2C+K&rft.au=Knecht%2C+W&rft.au=L%C3%B6ffler%2C+M&rft.au=Lill%2C+R&rft.aufirst=J&rft.aulast=Rawls&rft.date=2000&rft.genre=article&rft.issue=7&rft.jtitle=European+journal+of+biochemistry+%2F+FEBS&rft.pages=2079-87&rft.volume=267&rft_id=info%3Apmid%2F10727948&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><cite class="citation book">Lippincott. Biochemistry 4th. 2008.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E4%B9%B3%E6%B8%85%E9%85%B8&rft.au=Lippincott&rft.btitle=Biochemistry&rft.date=2008&rft.edition=4th&rft.genre=book&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.sciencelab.com/msds.php?msdsId=9926339">Orotic acid MSDS</a>. <span class="reference-accessdate"> [<span class="nowrap">2015-01-25</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20160927072216/http://www.sciencelab.com/msds.php?msdsId=9926339">存档</a>于2016-09-27）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E4%B9%B3%E6%B8%85%E9%85%B8&rft.btitle=Orotic+acid+MSDS&rft.genre=unknown&rft_id=http%3A%2F%2Fwww.sciencelab.com%2Fmsds.php%3FmsdsId%3D9926339&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span> （<a rel="nofollow" class="external text" href="//web.archive.org/web/20160927072216/http://www.sciencelab.com/msds.php?msdsId=9926339">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>）</span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="外部連結"><span id=".E5.A4.96.E9.83.A8.E9.80.A3.E7.B5.90"></span>外部連結</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%B9%B3%E6%B8%85%E9%85%B8&action=edit&section=6" title="编辑章节：外部連結"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r82655521">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:#f9f9f9;display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><div class="side-box side-box-right plainlinks sistersitebox" style="font-size:small;"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"> <div class="side-box-flex"> <div class="side-box-image"><span class="noviewer" typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png" decoding="async" width="30" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/45px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/59px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span></div> <div class="side-box-text plainlist"><a href="/wiki/%E7%BB%B4%E5%9F%BA%E5%85%B1%E4%BA%AB%E8%B5%84%E6%BA%90" title="维基共享资源">维基共享资源</a>中相关的多媒体资源：<b><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Orotic_acid?uselang=zh">乳清酸</a></b></div></div> </div> <ul><li><a href="/wiki/%E5%8C%BB%E5%AD%A6%E4%B8%BB%E9%A2%98%E8%AF%8D" title="医学主题词">醫學主題詞表（MeSH）</a>：<a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=Orotic+Acid">Orotic+Acid</a></li> <li><cite class="citation journal">Greenbaum, Sheldon B. Potential Metabolic Antagonists of Orotic Acid: 6-Uracilsulfonamide and 6-Uracil Methyl Sulfone1. Journal of the American Chemical Society. 1954, <b>76</b> (23): 6052. <a rel="nofollow" class="external text" href="https://doi.org/10.1021%2Fja01652a056"><span title="數位物件識別號">doi:10.1021/ja01652a056</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E4%B9%B3%E6%B8%85%E9%85%B8&rft.atitle=Potential+Metabolic+Antagonists+of+Orotic+Acid%3A+6-Uracilsulfonamide+and+6-Uracil+Methyl+Sulfone1&rft.aufirst=Sheldon+B.&rft.aulast=Greenbaum&rft.date=1954&rft.genre=article&rft.issue=23&rft.jtitle=Journal+of+the+American+Chemical+Society&rft.pages=6052&rft.volume=76&rft_id=info%3Adoi%2F10.1021%2Fja01652a056&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist 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class="navbox-group" style="width:1%"><a href="/wiki/%E5%98%8C%E5%91%A4%E4%BB%A3%E8%B0%A2" title="嘌呤代谢">嘌呤代谢</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">合成</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E6%A0%B8%E7%B3%96-5-%E7%A3%B7%E9%85%B8" title="核糖-5-磷酸">R5P</a> → <a href="/w/index.php?title=%E6%AC%A1%E9%BB%84%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="次黄苷酸（页面不存在）">IMP</a>：</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E6%A0%B8%E7%B3%96-5-%E7%A3%B7%E9%85%B8" title="核糖-5-磷酸">R5P</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96%E7%84%A6%E7%A3%B7%E9%85%B8" title="磷酸核糖焦磷酸">PRPP</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96%E8%83%BA&action=edit&redlink=1" class="new" title="磷酸核糖胺（页面不存在）">PRA</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=%E7%94%98%E6%B0%A8%E9%85%B0%E8%83%BA%E6%A0%B8%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="甘氨酰胺核苷酸（页面不存在）">GAR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96-N-%E7%94%B2%E9%85%B0%E5%9F%BA%E7%94%98%E6%B0%A8%E9%85%B0%E8%83%BA&action=edit&redlink=1" class="new" title="磷酸核糖-N-甲酰基甘氨酰胺（页面不存在）">FGAR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=5%27-%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96%E7%94%B2%E9%85%B0%E7%94%98%E6%B0%A8%E8%84%92&action=edit&redlink=1" class="new" title="5'-磷酸核糖甲酰甘氨脒（页面不存在）">FGAM</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=5%27-%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96-5-%E6%B0%A8%E5%9F%BA%E5%92%AA%E5%94%91&action=edit&redlink=1" class="new" title="5'-磷酸核糖-5-氨基咪唑（页面不存在）">AIR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=5%27-%E7%A3%B7%E9%85%B8%E6%A0%B8%E7%B3%96-4-%E7%BE%A7%E5%9F%BA-5-%E6%B0%A8%E5%9F%BA%E5%92%AA%E5%94%91&action=edit&redlink=1" class="new" title="5'-磷酸核糖-4-羧基-5-氨基咪唑（页面不存在）">CAIR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/5-%E6%B0%A8%E5%9F%BA%E5%92%AA%E5%94%91-4-(N-%E7%90%A5%E7%8F%80%E5%9F%BA)-%E7%94%B2%E9%85%B0%E8%83%BA%E6%A0%B8%E8%8B%B7%E9%85%B8" title="5-氨基咪唑-4-(N-琥珀基)-甲酰胺核苷酸">SAICAR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=AICA%E6%A0%B8%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="AICA核苷酸（页面不存在）">AICAR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=5-%E7%94%B2%E9%85%B0%E8%83%BA%E5%92%AA%E5%94%91-4-%E6%B0%A8%E7%94%B2%E9%85%B0%E6%A0%B8%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="5-甲酰胺咪唑-4-氨甲酰核苷酸（页面不存在）">FAICAR</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=%E6%AC%A1%E9%BB%84%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="次黄苷酸（页面不存在）">IMP</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">IMP → <a href="/wiki/%E8%85%BA%E8%8B%B7%E4%B8%80%E7%A3%B7%E9%85%B8" class="mw-redirect" title="腺苷一磷酸">AMP</a>：</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=%E8%85%BA%E8%8B%B7%E9%85%B8%E7%90%A5%E7%8F%80%E9%85%B8&action=edit&redlink=1" class="new" title="腺苷酸琥珀酸（页面不存在）">腺苷酸琥珀酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">IMP → <a href="/wiki/%E9%B8%9F%E8%8B%B7%E4%B8%80%E7%A3%B7%E9%85%B8" class="mw-redirect" title="鸟苷一磷酸">GMP</a>：</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=%E9%BB%84%E8%8B%B7%E9%85%B8&action=edit&redlink=1" class="new" title="黄苷酸（页面不存在）">黄苷酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">分解</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E6%AC%A1%E9%BB%84%E5%98%8C%E5%91%A4" title="次黄嘌呤">次黄嘌呤</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E9%BB%84%E5%98%8C%E5%91%A4" title="黄嘌呤">黄嘌呤</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E5%B0%BF%E9%85%B8" title="尿酸">尿酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=5-%E7%BE%9F%E5%9F%BA%E5%BC%82%E5%B0%BF%E9%85%B8&action=edit&redlink=1" class="new" title="5-羟基异尿酸（页面不存在）">5-羟基异尿酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E5%98%A7%E5%95%B6%E4%BB%A3%E8%AC%9D" title="嘧啶代謝">嘧啶代謝</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">合成</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=%E6%B0%A8%E7%94%B2%E9%85%B0%E7%A3%B7%E9%85%B8&action=edit&redlink=1" class="new" title="氨甲酰磷酸（页面不存在）">氨甲酰磷酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E6%B0%A8%E7%94%B2%E9%85%B0%E5%A4%A9%E5%86%AC%E6%B0%A8%E9%85%B8" title="氨甲酰天冬氨酸">氨甲酰天冬氨酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/4,5-%E4%BA%8C%E6%B0%A2%E4%B9%B3%E6%B8%85%E9%85%B8" title="4,5-二氢乳清酸">4,5-二氢乳清酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a class="mw-selflink selflink">乳清酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E4%B9%B3%E6%B8%85%E8%8B%B7-5%27-%E7%A3%B7%E9%85%B8" title="乳清苷-5'-磷酸">乳清苷酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%E5%B0%BF%E8%8B%B7%E9%85%B8" class="mw-redirect" title="尿苷酸">尿苷酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">分解</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><b><a href="/wiki/%E5%B0%BF%E5%98%A7%E5%95%B6" title="尿嘧啶">尿嘧啶</a></b>：<a href="/wiki/%E4%BA%8C%E6%B0%A2%E5%B0%BF%E5%98%A7%E5%95%B6" title="二氢尿嘧啶">二氢尿嘧啶</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/3-%E8%84%B2%E5%9F%BA%E4%B8%99%E9%85%B8" title="3-脲基丙酸">3-脲基丙酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%CE%92-%E4%B8%99%E6%B0%A8%E9%85%B8" title="Β-丙氨酸">β-丙氨酸</a><br /><b><a href="/wiki/%E8%83%B8%E8%85%BA%E5%98%A7%E5%95%B6" title="胸腺嘧啶">胸腺嘧啶</a></b>：<a href="/wiki/%E4%BA%8C%E6%B0%A2%E8%83%B8%E8%85%BA%E5%98%A7%E5%95%B6" title="二氢胸腺嘧啶">二氢胸腺嘧啶</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/wiki/%CE%92-%E8%84%B2%E5%9F%BA%E5%BC%82%E4%B8%81%E9%85%B8" title="Β-脲基异丁酸">β-脲基异丁酸</a><span style="white-space:nowrap; font-weight:bold;"> ·</span> <a href="/w/index.php?title=3-%E6%B0%A8%E5%9F%BA%E5%BC%82%E4%B8%81%E9%85%B8&action=edit&redlink=1" class="new" title="3-氨基异丁酸（页面不存在）">3-氨基异丁酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;background:transparent;color:inherit;"><div style="padding:0px;"><table class="navbox-columns-table" style="border-spacing: 0px; text-align:left;width:100%;"><tbody><tr style="vertical-align:top;"><td class="navbox-list" style="padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p><a href="/wiki/Template:%E5%8C%BB%E5%AD%A6%E5%AF%BC%E8%88%AA" title="Template:医学导航">医学导航</a>：<a href="/wiki/%E9%81%97%E4%BC%A0%E6%80%A7%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="遗传性代谢缺陷">遗传代谢缺陷</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:white;;width:10em;"><div> <p><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">代谢</a>、<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB%E4%B8%8E%E7%94%B5%E5%AD%90%E4%BC%A0%E9%80%92%E9%93%BE" title="Template:三羧酸循环酶类与电子传递链">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3%E9%85%B6%E7%B1%BB" title="Template:糖酵解酶类">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:糖原代谢酶类">g</a>/<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E9%85%B6%E7%B1%BB" title="Template:戊糖磷酸途径酶类">p</a>/<a href="/wiki/Template:%E9%86%A3%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:醣蛋白代謝酶">y</a>/<a href="/wiki/Template:%E8%9B%8B%E7%99%BD%E8%81%9A%E7%B3%96%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:蛋白聚糖代謝酶">i</a>,<a href="/wiki/Template:%E8%84%82%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:脂代谢酶类">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82%E4%BB%A3%E8%AC%9D" title="Template:磷脂代謝">h</a>/<a href="/wiki/Template:%E8%86%BD%E5%9B%BA%E9%86%87%E8%88%87%E9%A1%9E%E5%9B%BA%E9%86%87%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:膽固醇與類固醇代謝酶">s</a>/<a href="/wiki/Template:%E8%84%82%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%B0%A2" title="Template:脂蛋白代谢">l</a>/<a href="/wiki/Template:%E7%B3%96%E8%84%82%E8%88%87%E9%9E%98%E8%84%82%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:糖脂與鞘脂代謝酶">o</a>/<a href="/wiki/Template:%E9%A1%9E%E8%8A%B1%E7%94%9F%E9%85%B8%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:類花生酸代謝酶">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:氨基酸代谢酶类">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB" title="Template:尿素循环酶类">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:核苷酸代谢酶类">n</a>,<a href="/wiki/Template:%E5%8D%9F%E5%95%89%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:卟啉代谢酶类">m</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:silver;;width:10em;"><div> <p><a href="/wiki/Template:Disorders_of_TCA_and_ETC" class="mw-redirect" title="Template:Disorders of TCA and ETC">k</a>,<a href="/wiki/Template:%E5%85%88%E5%A4%A9%E6%80%A7%E7%B3%96%E7%B1%BB%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="Template:先天性糖类代谢缺陷">cgrp</a>/<a href="/wiki/Template:Glycoprotein_disorders" title="Template:Glycoprotein disorders">y</a>/<a href="/w/index.php?title=Template:Proteoglycan_disorders&action=edit&redlink=1" class="new" title="Template:Proteoglycan disorders（页面不存在）">i</a>,<a href="/wiki/Template:Fatty-acid_metabolism_disorders" title="Template:Fatty-acid metabolism disorders">f</a>/<a href="/w/index.php?title=Template:Phospholipid_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Phospholipid metabolism disorders（页面不存在）">h</a>/<a href="/w/index.php?title=Template:Defects_of_cholesterol_and_steroid_metabolism&action=edit&redlink=1" class="new" title="Template:Defects of cholesterol and steroid metabolism（页面不存在）">s</a>/<a href="/wiki/Template:Lipid_metabolism_disorders" title="Template:Lipid metabolism disorders">l</a>/<a href="/wiki/Template:Lipid_storage_disorders" title="Template:Lipid storage disorders">o</a>/<a href="/wiki/Template:Eicosanoid_metabolism_disorders" title="Template:Eicosanoid metabolism disorders">e</a>,<a href="/wiki/Template:Amino_acid_metabolic_pathology" title="Template:Amino acid metabolic pathology">au</a>,<a href="/w/index.php?title=Template:Inborn_errors_of_purine-pyrimidine_metabolism&action=edit&redlink=1" class="new" title="Template:Inborn errors of purine-pyrimidine metabolism（页面不存在）">n</a>,<a href="/w/index.php?title=Template:Heme_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Heme metabolism disorders（页面不存在）">m</a>,<a href="/wiki/Template:Eponymous_medical_signs_for_endocrinology,_nutrition,_and_metabolism" title="Template:Eponymous medical signs for endocrinology, nutrition, and metabolism">人名体征</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p>药物(<a href="/wiki/ATC%E4%BB%A3%E7%A0%81_(A16)" title="ATC代码 (A16)">A16</a>/<a href="/wiki/Template:%E8%A1%80%E8%84%82%E8%B0%83%E8%8A%82%E5%89%82" title="Template:血脂调节剂">C10</a>)、中间产物(<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%92%B0" title="Template:三羧酸循環">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3" title="Template:糖酵解">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E7%94%9F%E6%88%90%E4%B8%8E%E7%B3%96%E5%8E%9F%E5%88%86%E8%A7%A3%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:糖原生成与糖原分解代谢中间产物">g</a>/<a href="/wiki/Template:%E6%9E%9C%E7%B3%96%E4%B8%8E%E5%8D%8A%E4%B9%B3%E7%B3%96%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:果糖与半乳糖代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:戊糖磷酸途径中间产物">p</a>/<a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">y</a>/<a href="/wiki/Template:%E7%B3%96%E8%83%BA%E8%81%9A%E7%B3%96" title="Template:糖胺聚糖">i</a>,<a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">h</a>/<a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">s</a>/<a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">o</a>/<a href="/w/index.php?title=Template:Eicosanoids&action=edit&redlink=1" class="new" title="Template:Eicosanoids（页面不存在）">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="Template:尿素循环">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:核苷酸代谢中间产物">n</a>,<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">m</a>) </p> </div></td></tr></tbody></table></div></td></tr></tbody></table><div></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="collapsible-title navbox-title" colspan="2"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template:生物化学物质种类"><abbr title="查看该模板">查</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template talk:生物化学物质种类"><abbr title="讨论该模板">论</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:%E7%BC%96%E8%BE%91%E9%A1%B5%E9%9D%A2/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Special:编辑页面/Template:生物化学物质种类"><abbr title="编辑该模板">编</abbr></a></li></ul></div><div id="生物化學物質種類索引" style="font-size:110%;margin:0 5em"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6" title="生物化学">生物化學物質</a><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">種類</a>索引</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E7%B3%96%E7%B1%BB" title="Template:糖类">糖类</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E9%86%87" title="Template:醇">醇類</a></li> <li><a href="/wiki/Template:%E5%A4%9A%E5%85%83%E9%86%87" title="Template:多元醇">糖醇</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">醣蛋白</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%8B%B7" title="Template:糖苷">苷</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E8%84%82%E7%B1%BB" title="Template:脂类">酯質</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E7%B1%BB%E8%8A%B1%E7%94%9F%E9%85%B8%E7%B1%BB" title="Template:类花生酸类">类花生酸类</a></li> <li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8" title="Template:脂肪酸">脂肪酸</a> <ul><li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">中間物</a></li></ul></li> <li><a href="/wiki/Template:Glycerides" title="Template:Glycerides">甘油酯</a></li> <li><a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">磷脂</a></li> <li><a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">鞘脂類</a></li> <li><a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">胆固醇与甾体中间产物</a></li></ul> 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href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E5%9B%9B%E5%90%A1%E5%92%AF" title="Template:四吡咯">四吡咯</a> <ul><li><a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">检索自“<a dir="ltr" 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