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href="/plosntds/article?id=10.1371/journal.pntd.0012794">Revisiting What Constitutes a Neglected Tropical Disease?</a></h2> <div class="blurb"> <p><i>PLOS Neglected Tropical Diseases</i> publishes research devoted to pathogenesis and other clinical aspects, epidemiology, prevention, diagnosis, treatment, and control of the neglected tropical diseases (NTDs), as well as work relevant to public health policy. We define NTDs as poverty-promoting infectious diseases that can negatively impact the quality of life in rural areas and poor urban areas of low- and middle-income countries but which can also affect specific...</p> </div> </div> <p class="credits">Image credit: NIAID</p><a class="block-image" alt="Revisiting What Constitutes a Neglected Tropical Disease?" href="/plosntds/article?id=10.1371/journal.pntd.0012794"><img alt="Revisiting What Constitutes a Neglected Tropical Disease?" data-file-extension="jpg" src="/plosntds/indirect/f908a87d2f092792dc21a528888d8925ad18621df74fe5711d20a0835193f2fd"></a> </article> <div id="article-list"> <h3>Recently Published Articles</h3> <section> <ul id="article-results" class="list-plain results"> <li><a href="article?id=10.1371/journal.pntd.0012954" data-tooltip class="truncated-tooltip" title="Characterization of dengue patients in Vietnam: Clinical, virological, and IL-10 profiles during 2021– 2022 outbreaks">Characterization of dengue patients in Vietnam: Clinical, virological, and IL-10 profiles during 2021– 2022 outbreaks</a></li> <li><a href="article?id=10.1371/journal.pntd.0012942" data-tooltip class="truncated-tooltip" title=" <i>Schistosoma mansoni</i> x <i>S. haematobium</i> hybrids frequently infecting sub-Saharan migrants in southeastern Europe: Egg DNA genotyping assessed by RD-PCR, sequencing and cloning"> <i>Schistosoma mansoni</i> x <i>S. haematobium</i> hybrids frequently infecting sub-Saharan migrants in southeastern Europe: Egg DNA genotyping assessed by RD-PCR, sequencing and cloning</a></li> <li><a href="article?id=10.1371/journal.pntd.0012930" data-tooltip class="truncated-tooltip" title="Potential vertical transmission of genetically diverse <i>Trypanosoma cruzi</i> in natural rodent populations">Potential vertical transmission of genetically diverse <i>Trypanosoma cruzi</i> in natural rodent populations</a></li> </ul> </section> <div class="more-link"> <a href="search?sortOrder=DATE_NEWEST_FIRST&filterStartDate=2025-03-03&filterEndDate=2025-04-02&filterJournals=PLoSNTD&q=">See all articles</a> </div> <script src="/resource/js/vendor/jquery.dotdotdot.js" type="text/javascript"></script> </div> <div id="issue"> <a href="/plosntds/issue"> <img src="/plosntds/article/figure/image?size=medium&id=10.1371/image.pntd.v19.i02.g001" class="current-img" alt="Current Issue"> </a> <p class="boxtitle"><a href="/plosntds/issue">Current Issue</a> <span class="subhead">February 2025</span></p> </div> </div> <div class="row two"> <article class="block medium image" id="cellcat-1-2"> <div class="block-content"> <p class="date">02/06/2025</p> <p class="category">Research Article</p> <h2 class="title"><a alt="Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system" href="/plosntds/article?id=10.1371/journal.pntd.0012555">Comprehensive proteolytic profiling of <i>Aedes aegypti</i> mosquito midgut extracts: Unraveling the blood meal protein digestion system</a></h2> <div class="blurb"> <p>To sustain the gonotrophic cycle, the Aedes aegypti mosquito must acquire a blood meal from a human or other vertebrate host. However, in the process of blood feeding, the mosquito may facilitate the transmission of several bloodborne viral pathogens (e.g., dengue, Zika, and chikungunya). The blood meal is essential...</p> </div> </div> <p class="credits">Image credit: pntd.0012555</p><a class="block-image" alt="Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system" href="/plosntds/article?id=10.1371/journal.pntd.0012555"><img alt="Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system" data-file-extension="jpg" src="/plosntds/indirect/39f1c30a970694d2680464723ab0bb22a056b232bb42d8345bc098a48f33ebbd"></a> </article> <article class="block medium image" id="cellcat-1-3"> <div class="block-content"> <p class="date">02/18/2025</p> <p class="category">Research Article</p> <h2 class="title"><a alt="Prevalence of antibodies against dengue virus in the city of Buenos Aires: Results of a probabilistic population survey" href="/plosntds/article?id=10.1371/journal.pntd.0012886">Prevalence of antibodies against dengue virus in the city of Buenos Aires: Results of a probabilistic population survey</a></h2> <div class="blurb"> <p>Dengue is a rapidly growing global health issue. In Argentina, the disease burden is primarily based on case reports or retrospective series; however, there are no prospective probabilistic studies available. To estimate the seroprevalence of antibodies against the dengue virus (DENV) in adult residents of Buenos Aires, at the end of the 2023 season, which culminated in...</p> </div> </div> <p class="credits">Image credit: NIAID</p><a class="block-image" alt="Prevalence of antibodies against dengue virus in the city of Buenos Aires: Results of a probabilistic population survey" href="/plosntds/article?id=10.1371/journal.pntd.0012886"><img alt="Prevalence of antibodies against dengue virus in the city of Buenos Aires: Results of a probabilistic population survey" data-file-extension="jpg" src="/plosntds/indirect/aed2749c9fc9247f1931d68c74e8001d23d13e08ff302e8fe5c067592b44a483"></a> </article> </div> <div class="row three"> <div class="column left"> <article class="block large image" id="cellcat2-1"> <div class="block-content"> <p class="date">01/23/2025</p> <p class="category">Policy Platform</p> <h2 class="title"><a alt="Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect" href="/plosntds/article?id=10.1371/journal.pntd.0012796">Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect</a></h2> <div class="blurb"> <p>The global priorities in the field of infectious diseases are constantly changing. 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It is preventable with vaccination, and Water, Sanitation, and Hygiene (WASH) improvements. However, the impact of vaccination in endemic settings remains unclear. 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Current treatments face issues like resistance, safety, efficacy, and cost. 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