Diagnostic criteria and classification of mastocytosis: a consensus proposal

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new collection</label> </li> <li> <input type="radio" id="collections-action-panel-existing" class="collections-existing" name="collections" value="existing" checked="true" data-ga-category="save_share" data-ga-action="collections" data-ga-label="collections_radio_existing"> <label for="collections-action-panel-existing">Add to an existing collection</label> </li> </ul> </div> <div class="controls-wrapper"> <div class="action-panel-control-wrap new-collections-controls"> <label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk"> Name your collection: </label> <input type="text" name="add-to-new-collection" id="collections-action-panel-add-to-new" class="collections-action-add-to-new" pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/" maxlength="100" data-ga-category="save_share" data-ga-action="create_collection" data-ga-label="non_favorties_collection"> <div class="collections-new-name-too-long usa-input-error-message selection-validation-message"> Name must be less than 100 characters </div> </div> <div class="action-panel-control-wrap existing-collections-controls"> <label for="collections-action-panel-add-to-existing" class="action-panel-label"> Choose a collection: </label> <select id="collections-action-panel-add-to-existing" class="action-panel-selector collections-action-add-to-existing" data-ga-category="save_share" data-ga-action="select_collection" data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"> </select> <div class="collections-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your collection due to an error<br> <a href="#">Please try again</a> </div> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore data-ga-category="save_share" data-ga-action="collections" data-ga-label="add"> Add </button> <button class="action-panel-cancel" aria-label="Close 'Add to Collections' panel" ref="linksrc=close_collections_panel" aria-controls="collections-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="collections" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="bibliography-action-panel" class="bibliography-action-panel action-panel in-progress-dots-panel" aria-hidden="true" data-bibliography-open-panel-enabled="false" data-bibliography-open-panel-url-hash="#open-bibliography-panel"> <div class="inner-wrap"> <h3 class="action-panel-heading"> Add to My Bibliography </h3> <form id="bibliography-action-panel-form" class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-add-to-bibliography-max-amount="100" data-add-to-bibliography-batch-size="10" data-bibliography-delegates-url="/list-bibliography-delegates/" data-add-to-bibliography-url="/add-to-bibliography/" data-get-article-ids-by-search-url="/get-article-ids-by-search/" data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/"> <input type="hidden" name="csrfmiddlewaretoken" value="i3D7cvyVmIlFGrlcMTu8EGGfYplA0Ymy73Um8ZQjx1q5TwfPQIrlockAlREn1uZ3"> <div class="action-panel-control-wrap bibliographies-controls"> <div class="choice-group"> <ul class="bibliographies-action-add radio-group-items"> <li> <input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/> <label for="my-bibliography">My Bibliography</label> </li> </ul> </div> </div> <div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your delegates due to an error<br> <a href="#">Please try again</a> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore> Add </button> <button class="action-panel-cancel" aria-label="Close 'Add to bibliography' panel" ref="linksrc=close_bibliography_panel" aria-controls="bibliography-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="mybib" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true" data-saved-search-open-panel-enabled="false" data-saved-search-open-panel-url-hash="#open-saved-search-panel"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Your saved search </h2> <form id="saved-search-action-panel-form" class="saved-search-action-panel-form action-panel-content action-form" data-create-saved-search-url="/create-saved-search/" data-try-search-terms-url="/try-search-term/" data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/"> <input type="hidden" name="csrfmiddlewaretoken" value="i3D7cvyVmIlFGrlcMTu8EGGfYplA0Ymy73Um8ZQjx1q5TwfPQIrlockAlREn1uZ3"> <div class="action-panel-control-wrap"> <label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk"> Name of saved search: </label> <input maxlength="200" type="text" name="saved-search-name" id="saved-search-name" class="saved-search-name" value="" required pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"> </div> <div class="action-panel-control-wrap"> <label for="saved-search-term" class="action-panel-label required-field-asterisk"> Search terms: </label> <textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea> </div> <div class="test-search-term-wrap"> <a href="#" class="try-search-term">Test search terms</a> </div> <div class="choice-group action-panel-extra-margin-top"> <span class="action-panel-label" id="fieldset-label"> Would you like email updates of new search results? </span> <fieldset id="saved-search-alert" aria-describedby="fieldset-label"> <legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend> <ul class="radio-group-items"> <li> <input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked> <label for="saved-search-alert-yes" class="action-panel-label">Yes</label> </li> <li> <input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no"> <label for="saved-search-alert-no" class="action-panel-label">No</label> </li> </ul> </fieldset> </div> <div class="alert-schedule-wrap"> <div class="action-panel-control-wrap"> <label class="action-panel-label"> Email: </label> <span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span> </div> <div class="action-panel-control-wrap action-panel-extra-margin-top"> <label for="saved-search-frequency" class="action-panel-label"> Frequency: </label> <select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency"> <option value="monthly">Monthly</option> <option value="weekly">Weekly</option> <option value="daily">Daily</option> </select> </div> <div class="action-panel-control-wrap saved-search-monthly-additional"> <label for="saved-search-monthly-on-day" class="action-panel-label"> Which day? </label> <select id="saved-search-monthly-on-day" class="no-border-panel-selector"> <option value="Sunday">The first Sunday</option> <option value="Monday">The first Monday</option> <option value="Tuesday">The first Tuesday</option> <option value="Wednesday">The first Wednesday</option> <option value="Thursday">The first Thursday</option> <option value="Friday">The first Friday</option> <option value="Saturday">The first Saturday</option> <option value="day">The first day</option> <option value="weekday">The first weekday</option> </select> </div> <div class="action-panel-control-wrap saved-search-weekly-additional"> <label for="saved-search-weekly-on-day" class="action-panel-label"> Which day? </label> <select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day"> <option value="Sunday">Sunday</option> <option value="Monday">Monday</option> <option value="Tuesday">Tuesday</option> <option value="Wednesday">Wednesday</option> <option value="Thursday">Thursday</option> <option value="Friday">Friday</option> <option value="Saturday">Saturday</option> </select> </div> <div class="action-panel-control-wrap"> <label for="saved-search-report" class="action-panel-label"> Report format: </label> <select id="saved-search-report" class="no-border-panel-selector saved-search-report"> <option value="DocSum">Summary</option> <option value="DocSumText">Summary (text)</option> <option value="Abstract">Abstract</option> <option value="AbstractText">Abstract (text)</option> <option value="MEDLINE">PubMed</option> </select> </div> <div class="action-panel-control-wrap"> <label for="saved-search-amount" class="action-panel-label"> Send at most: </label> <select id="saved-search-amount" class="no-border-panel-selector saved-search-amount"> <option value="1">1 item</option> <option value="5" selected>5 items</option> <option value="10">10 items</option> <option value="20">20 items</option> <option value="50">50 items</option> <option value="100">100 items</option> <option value="200">200 items</option> </select> </div> <div> <input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result"> <label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox"> Send even when there aren't any new results </label> </div> <div class="action-panel-control-wrap option-text-in-email-wrap"> <label for="saved-search-email-text" class="action-panel-label"> Optional text in email: </label> <textarea name="saved-search-email-text" id="saved-search-email-text" class="saved-search-email-text"></textarea> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Saving..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Save </button> <button class="action-panel-cancel" aria-label="Close 'Your saved search' panel" ref="linksrc=close_saved_search_panel" aria-controls="saved-search-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Create a file for external citation management software </h2> <form id="citation-manager-action-panel-form" class="action-panel-content action-form" action="/results-export-ids/" data-by-search-action="/results-export-search-data/" data-by-ids-action="/results-export-ids/" method="post" data-by-search-method="post" data-by-ids-method="post"> <input type="hidden" name="csrfmiddlewaretoken" value="i3D7cvyVmIlFGrlcMTu8EGGfYplA0Ymy73Um8ZQjx1q5TwfPQIrlockAlREn1uZ3"> <input name="results-format" type="hidden" value="pubmed"/> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Sending..." data-ga-category="save_share" data-ga-action="citation_manager" data-ga-label="save"> Create file </button> <button class="action-panel-cancel" aria-label="Close 'Send citations to citation manager' panel" ref="linksrc=close_citation_manager_panel" aria-controls="citation-manager-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="citation_manager" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Your RSS Feed </h2> <form id="rss-action-panel-form" class="rss-action-panel-form action-panel-content action-form" data-create-rss-feed-url="/create-rss-feed-url/" data-search-form-term-value=""> <input type="hidden" name="csrfmiddlewaretoken" value="i3D7cvyVmIlFGrlcMTu8EGGfYplA0Ymy73Um8ZQjx1q5TwfPQIrlockAlREn1uZ3"> <div class="action-panel-control-wrap"> <label for="rss-name" class="action-panel-label required-field-asterisk"> Name of RSS Feed: </label> <input maxlength="200" placeholder="Name" type="text" name="rss-name" id="rss-name" class="rss-name" value='' required pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"> </div> <div class="rss-limit-wrap"> <div class="action-panel-control-wrap action-panel-extra-margin-top"> <label for="rss-limit" class="action-panel-label"> Number of items displayed: </label> <select id="rss-limit" class="no-border-panel-selector rss-limit"> <option value="5">5</option> <option value="10">10</option> <option value="15" selected="selected">15</option> <option value="20">20</option> <option value="50">50</option> <option value="100">100</option> </select> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Creating..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Create RSS </button> <button class="action-panel-cancel" aria-label="Close 'Your RSS' panel" ref="linksrc=close_rss_panel" aria-controls="rss-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert" data-ga-label="cancel"> Cancel </button> </div> <div class="action-panel-control-wrap rss-link-copy-wrap"> <label for="rss-link" class="usa-sr-only">RSS Link</label> <input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link"> <button type="button" disabled class="rss-link-copy-button disabled" data-ga-category="save_share" data-ga-action="rss" data-ga-label="copy"> Copy </button> </div> </form> </div> </div> </div> </div> <div class="article-page" id="article-page" data-article-pmid="11377686"> <aside class="page-sidebar"> <div class="inner-wrap"> <div class="full-text-links"> <div class="full-view"> <h3 class="title"> Full text links </h3> <div class="full-text-links-list"> <a class="link-item dialog-focus" href="https://linkinghub.elsevier.com/retrieve/pii/S0145-2126(01)00038-8" target="_blank" rel="noopener" ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=3048&itool=Abstract-def&log$=linkouticon&uid=11377686&db=pubmed&nlmid=7706787" title="See full text options at Elsevier Science" data-ga-category="full_text" data-ga-action="Elsevier Science" data-ga-label="11377686" ><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif" alt="full text provider logo"><span class="text"> Elsevier Science </span></a> </div> </div> <div class="short-view"> <a href="#" class="full-text-links-button full-text-links-dialog-trigger"> Full text links </a> </div> </div> <div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger" aria-label="Open dialog with citation text in different styles" data-ga-category="save_share" data-ga-action="cite" data-ga-label="open" data-all-citations-url="/11377686/citations/" data-citation-style="nlm" data-pubmed-format-link="/11377686/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="11377686" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger" aria-label="Save article in MyNCBI collections." data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_button" data-collections-open-dialog-enabled="false" data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F11377686%2F%23open-collections-dialog" data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog" class="dialog collections-dialog" aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form" class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-existing-collections-url="/list-existing-collections/" data-add-to-existing-collection-url="/add-to-existing-collection/" data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/" data-myncbi-max-collection-name-length="100" data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="i3D7cvyVmIlFGrlcMTu8EGGfYplA0Ymy73Um8ZQjx1q5TwfPQIrlockAlREn1uZ3"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio" id="collections-action-dialog-new" class="collections-new" name="collections" value="new" data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio" id="collections-action-dialog-existing" class="collections-existing" name="collections" value="existing" checked="true" data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk"> Name your collection: </label><input type="text" name="add-to-new-collection" id="collections-action-dialog-add-to-new" class="collections-action-add-to-new" pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/" maxlength="100" data-ga-category="collections_button" data-ga-action="create_collection" data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message"> Name must be less than 100 characters </div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label"> Choose a collection: </label><select id="collections-action-dialog-add-to-existing" class="action-panel-selector collections-action-add-to-existing" data-ga-category="collections_button" data-ga-action="select_collection" data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore data-ga-category="collections_button" data-ga-action="click" data-ga-label="add"> Add </button><button class="action-panel-cancel" aria-label="Close 'Add to Collections' panel" ref="linksrc=close_collections_panel" aria-controls="collections-action-panel" aria-expanded="false" data-ga-category="collections_button" data-ga-action="click" data-ga-label="cancel"> Cancel </button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger" title="Open dialog with more actions to take" ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format" data-default-format-value="abstract" data-current-format-value="abstract" role="region"><button class="trigger usa-button" title="Change format" data-ga-category="display_options" data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title"> Display options </div><div class="content"><div class="format-container"><span class="option-label"> Format </span><select name="format" data-initial-value="abstract" aria-label="Display format" id="sidebar-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div> <div class="social-sharing"> <h3 class="title"> Share </h3> <ul class="social-sharing-links usa-unstyled-list"> <li> <a 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</div> </aside> <main class="article-details" id="article-details">   <header class="heading" id="heading"> <div class="full-view" id="full-view-heading"> <div class="article-citation"> <div class="publication-type" >Review</div> <div class="article-source"> <div class="journal-actions dropdown-block"><button id="full-view-journal-trigger" class="journal-actions-trigger trigger" ref="linksrc=journal_actions_btn" title="Leukemia research" tabindex="0" aria-controls="full-view-journal" aria-expanded="false" aria-label="Toggle dropdown menu for journal Leukemia research" data-pinger-ignore> Leuk Res </button><div id="full-view-journal" class="journal-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for journal Leukemia research"><div class="title">Actions</div><div class="content"><ul class="journal-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Leuk+Res%22%5Bjour%5D&sort=date&sort_order=desc" data-href="/?term=%22Leuk+Res%22%5Bjour%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_journal_name_link&journal_abbrev=Leuk Res" data-ga-category="search" data-ga-action="journal_link" data-ga-label="Leuk Res"> Search in PubMed </a></li><li><a class="search-in-nlm-catalog-link dropdown-block-link" ref ="linksrc=search_in_nlm_catalog_link" href="https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Leuk+Res%22%5BTitle+Abbreviation%5D" data-ga-category="search_catalog" data-ga-action="journal_link" data-ga-label="Leuk Res"> Search in NLM Catalog </a></li><li><a class="add-to-search-link dropdown-block-link" ref ="linksrc=add_to_search_link" role="button" data-search-term='"Leuk Res"[jour]' data-ga-category="search" data-ga-action="add_to_search" data-ga-label='"Leuk Res"[jour]' href="#"> Add to Search </a></li></ul></div></div></div><span class="period">. </span><span class="cit">2001 Jul;25(7):603-25.</span> </div> <span class="citation-doi"> doi: 10.1016/s0145-2126(01)00038-8. </span> </div> <h1 class="heading-title"> Diagnostic criteria and classification of mastocytosis: a consensus proposal </h1> <div class="inline-authors"> <div class="authors"> <div class="authors-list"> <span class="authors-list-item "><a class="full-name" href="/?term=Valent+P&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="P Valent">P Valent</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" title="Department of Internal Medicine I, Division of Hematology, University of Vienna, Währinger Gürtel 18-20 Vienna, Austria. peter.valent@akh-wien.ac.at" href="#full-view-affiliation-1" ref="linksrc=author_aff"> 1 </a></sup><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Horny+HP&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="H P Horny">H P Horny</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Escribano+L&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="L Escribano">L Escribano</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Longley+BJ&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="B J Longley">B J Longley</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Li+CY&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="C Y Li">C Y Li</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Schwartz+LB&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="L B Schwartz">L B Schwartz</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Marone+G&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="G Marone">G Marone</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Nu%C3%B1ez+R&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R Nuñez">R Nuñez</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Akin+C&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="C Akin">C Akin</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sotlar+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Sotlar">K Sotlar</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sperr+WR&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="W R Sperr">W R Sperr</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Wolff+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Wolff">K Wolff</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Brunning+RD&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R D Brunning">R D Brunning</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Parwaresch+RM&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R M Parwaresch">R M Parwaresch</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Austen+KF&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K F Austen">K F Austen</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Lennert+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Lennert">K Lennert</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Metcalfe+DD&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="D D Metcalfe">D D Metcalfe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Vardiman+JW&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="J W Vardiman">J W Vardiman</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Bennett+JM&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="J M Bennett">J M Bennett</a></span> </div> </div> </div> <div class="short-article-details"> Affiliations <button class="more-details" id="toggle-authors" data-alt-text="Collapse" aria-controls="expanded-authors" aria-expanded="false" data-pinger-ignore data-fetch-url="/11377686/long-authors/" data-id-prefix=""> <span class="title"> Expand </span> </button> </div> <div class="extended-article-details" id="expanded-authors" aria-hidden="true"> <div class="expanded-authors" id="full-view-expanded-authors"> <div class="affiliations"> <h3 class="title"> Affiliation </h3> <ul class="item-list"> <li data-affiliation-id="full-view-affiliation-1" id="full-view-affiliation-1" ><sup class="key">1</sup> Department of Internal Medicine I, Division of Hematology, University of Vienna, Währinger Gürtel 18-20 Vienna, Austria. peter.valent@akh-wien.ac.at</li> </ul> </div> </div> </div> <ul class="identifiers" id="full-view-identifiers"> <li> <span class="identifier pubmed"> <span class="id-label"> PMID: </span> <strong class="current-id" title="PubMed ID">11377686</strong> </span> </li> <li> <span class="identifier doi"> <span class="id-label"> DOI: </span> <a class="id-link" target="_blank" rel="noopener" ref="linksrc=article_id_link&article_id=10.1016/s0145-2126(01)00038-8&id_type=DOI" href="https://doi.org/10.1016/s0145-2126(01)00038-8" data-ga-category="full_text" data-ga-action="DOI" > 10.1016/s0145-2126(01)00038-8 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> <div class="short-view" id="short-view-heading"> <div class="publication-type" >Review</div> <h1 class="heading-title"> Diagnostic criteria and classification of mastocytosis: a consensus proposal </h1> <div class="short-citation"> <span class="authors-list"> <span class="authors-list-item "><span class="full-name">P Valent</span><span class="citation-separator"> et al.</span></span> </span> <span class="citation-journal"> Leuk Res<span class="citation-separator">.</span> </span> <span class="date"> <span class="citation-year">2001 Jul</span><span class="citation-separator">.</span> </span> </div> <div class="more-article-details-section with-display-settings"> <button class="more-article-details" id="toggle-article-details" data-alt-text="Hide details" ref="linksrc=toggle_article_details" aria-controls="full-article-details" aria-expanded="false" data-fetch-url="/11377686/long-authors/" data-id-prefix=""> <span 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dropdown-block"><button id="short-view-journal-trigger" class="journal-actions-trigger trigger" ref="linksrc=journal_actions_btn" title="Leukemia research" tabindex="0" aria-controls="short-view-journal" aria-expanded="false" aria-label="Toggle dropdown menu for journal Leukemia research" data-pinger-ignore> Leuk Res </button><div id="short-view-journal" class="journal-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for journal Leukemia research"><div class="title">Actions</div><div class="content"><ul class="journal-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Leuk+Res%22%5Bjour%5D&sort=date&sort_order=desc" data-href="/?term=%22Leuk+Res%22%5Bjour%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_journal_name_link&journal_abbrev=Leuk Res" data-ga-category="search" data-ga-action="journal_link" data-ga-label="Leuk Res"> Search in PubMed </a></li><li><a class="search-in-nlm-catalog-link dropdown-block-link" ref ="linksrc=search_in_nlm_catalog_link" href="https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Leuk+Res%22%5BTitle+Abbreviation%5D" data-ga-category="search_catalog" data-ga-action="journal_link" data-ga-label="Leuk Res"> Search in NLM Catalog </a></li><li><a class="add-to-search-link dropdown-block-link" ref ="linksrc=add_to_search_link" role="button" data-search-term='"Leuk Res"[jour]' data-ga-category="search" data-ga-action="add_to_search" data-ga-label='"Leuk Res"[jour]' href="#"> Add to Search </a></li></ul></div></div></div><span class="period">. </span><span class="cit">2001 Jul;25(7):603-25.</span> </div> <span class="citation-doi"> doi: 10.1016/s0145-2126(01)00038-8. </span> </div> <div class="expanded-authors" id="short-view-expanded-authors"> <div class="authors"> <h3 class="title"> Authors </h3> <div class="authors-list"> <span class="authors-list-item "><a class="full-name" href="/?term=Valent+P&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="P Valent">P Valent</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" title="Department of Internal Medicine I, Division of Hematology, University of Vienna, Währinger Gürtel 18-20 Vienna, Austria. peter.valent@akh-wien.ac.at" href="#short-view-affiliation-1" ref="linksrc=author_aff"> 1 </a></sup><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Horny+HP&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="H P Horny">H P Horny</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Escribano+L&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="L Escribano">L Escribano</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Longley+BJ&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="B J Longley">B J Longley</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Li+CY&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="C Y Li">C Y Li</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Schwartz+LB&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="L B Schwartz">L B Schwartz</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Marone+G&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="G Marone">G Marone</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Nu%C3%B1ez+R&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R Nuñez">R Nuñez</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Akin+C&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="C Akin">C Akin</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sotlar+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Sotlar">K Sotlar</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sperr+WR&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="W R Sperr">W R Sperr</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Wolff+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Wolff">K Wolff</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Brunning+RD&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R D Brunning">R D Brunning</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Parwaresch+RM&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="R M Parwaresch">R M Parwaresch</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Austen+KF&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K F Austen">K F Austen</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Lennert+K&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="K Lennert">K Lennert</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Metcalfe+DD&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="D D Metcalfe">D D Metcalfe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Vardiman+JW&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="J W Vardiman">J W Vardiman</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Bennett+JM&cauthor_id=11377686" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="J M Bennett">J M Bennett</a></span> </div> </div> <div class="affiliations"> <h3 class="title"> Affiliation </h3> <ul class="item-list"> <li data-affiliation-id="short-view-affiliation-1" id="short-view-affiliation-1" ><sup class="key">1</sup> Department of Internal Medicine I, Division of Hematology, University of Vienna, Währinger Gürtel 18-20 Vienna, Austria. peter.valent@akh-wien.ac.at</li> </ul> </div> </div> <ul class="identifiers" id="short-view-identifiers"> <li> <span class="identifier pubmed"> <span class="id-label"> PMID: </span> <strong class="current-id" title="PubMed ID">11377686</strong> </span> </li> <li> <span class="identifier doi"> <span class="id-label"> DOI: </span> <a class="id-link" target="_blank" rel="noopener" ref="linksrc=article_id_link&article_id=10.1016/s0145-2126(01)00038-8&id_type=DOI" href="https://doi.org/10.1016/s0145-2126(01)00038-8" data-ga-category="full_text" data-ga-action="DOI" > 10.1016/s0145-2126(01)00038-8 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> </div> </header> <div class="actions-buttons inline"><div class="inner-wrap"><button class="full-text-links-button full-text-links-dialog-trigger" title="Open dialog with full text links" ref="linksrc=full_text_links"> Full text links </button><button class="citation-button citation-dialog-trigger" aria-label="Open dialog with citation text in different styles" data-ga-category="save_share" data-ga-action="cite" data-ga-label="open" data-all-citations-url="/11377686/citations/" data-citation-style="nlm" data-pubmed-format-link="/11377686/export/"><span class="button-label">Cite</span></button><button class="more-actions-button more-actions-dialog-trigger" title="Open dialog with more actions to take" ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format" data-default-format-value="abstract" data-current-format-value="abstract" role="region"><button class="trigger usa-button" title="Change format" data-ga-category="display_options" data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title"> Display options </div><div class="content"><div class="format-container"><span class="option-label"> Format </span><select name="format" data-initial-value="abstract" aria-label="Display format" id="inline-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div> <div class="abstract" id="abstract"> <h2 class="title"> Abstract </h2> <div class="abstract-content selected" id="eng-abstract"> <p> The term 'mastocytosis' denotes a heterogeneous group of disorders characterized by abnormal growth and accumulation of mast cells (MC) in one or more organ systems. Over the last 20 years, there has been an evolution in accepted classification systems for this disease. In light of such developments and novel useful markers, it seems appropriate now to re-evaluate and update the classification of mastocytosis. Here, we propose criteria to delineate categories of mastocytosis together with an updated consensus classification system. In this proposal, the diagnosis cutaneous mastocytosis (CM) is based on typical clinical and histological skin lesions and absence of definitive signs (criteria) of systemic involvement. Most patients with CM are children and present with maculopapular cutaneous mastocytosis (=urticaria pigmentosa, UP). Other less frequent forms of CM are diffuse cutaneous mastocytosis (DCM) and mastocytoma of skin. Systemic mastocytosis (SM) is commonly seen in adults and defined by multifocal histological lesions in the bone marrow (affected almost invariably) or other extracutaneous organs (major criteria) together with cytological and biochemical signs (minor criteria) of systemic disease (SM-criteria). SM is further divided into the following categories: indolent systemic mastocytosis (ISM), SM with an associated clonal hematologic non-mast cell lineage disease (AHNMD), aggressive systemic mastocytosis (ASM), and mast cell leukemia (MCL). Patients with ISM usually have maculopapular skin lesions and a good prognosis. In the group with associated hematologic disease, the AHNMD should be classified according to FAB/WHO criteria. ASM is characterized by impaired organ-function due to infiltration of the bone marrow, liver, spleen, GI-tract, or skeletal system, by pathologic MC. MCL is a 'high-grade' leukemic disease defined by increased numbers of MC in bone marrow smears (>or=20%) and peripheral blood, absence of skin lesions, multiorgan failure, and a short survival. In typical cases, circulating MC amount to >or=10% of leukocytes (classical form of MCL). Mast cell sarcoma is a unifocal tumor that consists of atypical MC and shows a destructive growth without (primary) systemic involvement. This high-grade malignant MC disease has to be distinguished from a localized benign mastocytoma in either extracutaneous organs (=extracutaneous mastocytoma) or skin. Depending on the clinical course of mastocytosis and development of an AHNMD, patients can shift from one category of MC disease into another. In all categories, mediator-related symptoms may occur and may represent a serious clinical problem. All categories of mastocytosis should be distinctively separated from reactive MC hyperplasia, MC activation syndromes, and a more or less pronounced increase in MC in myelogenous malignancies other than mastocytosis. Criteria proposed in this article should be helpful in this regard. </p> </div> </div> <p class="disclaimer" id="disclaimer"> <a href="/disclaimer/" target="_blank" ga_category="literature_resources" ga_action="disclaimer_link" ga_label="under_abstract">PubMed Disclaimer</a> </p> <div class="linked-articles" id="linked-commentary"> <h2 class="title"> Comment in </h2> <ul class="item-list usa-unstyled-list"> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/11916523/" ref="article_id=11916523&linksrc=comments_link" data-ga-category="comment_correction" data-ga-action="abstract_page_link" data-ga-label="linked-commentary"> Classification of cutaneous mastocytosis: a modified consensus proposal. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Hartmann K, Henz BM.</span> <span class="docsum-authors short-authors">Hartmann K, et al.</span> <span class="docsum-journal-citation 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href="/?term=%22Clone+Cells%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Clone+Cells%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Clone Cells/pathology"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Clone Cells / pathology"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Clone+Cells" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Clone Cells / pathology"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Clone Cells/pathology"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Clone Cells/pathology"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions 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Leukemia, Mast-Cell / classification" tabindex="0" aria-controls="keyword-actions-mesh-terms-15" aria-expanded="false" data-pinger-ignore> Leukemia, Mast-Cell / classification </button><div id="keyword-actions-mesh-terms-15" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Leukemia, Mast-Cell / classification"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Leukemia%2C+Mast-Cell%2Fclassification%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Leukemia%2C+Mast-Cell%2Fclassification%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Leukemia, Mast-Cell/classification"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Leukemia, Mast-Cell / classification"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" 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ref="linksrc=add_to_search_link" role="button" data-search-term=""Leukemia, Mast-Cell/diagnosis"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Leukemia, Mast-Cell/diagnosis"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Leukemia, Mast-Cell / epidemiology" tabindex="0" aria-controls="keyword-actions-mesh-terms-17" aria-expanded="false" data-pinger-ignore> Leukemia, Mast-Cell / epidemiology </button><div id="keyword-actions-mesh-terms-17" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Leukemia, Mast-Cell / epidemiology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Leukemia%2C+Mast-Cell%2Fepidemiology%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Leukemia%2C+Mast-Cell%2Fepidemiology%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Leukemia, Mast-Cell/epidemiology"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Leukemia, Mast-Cell / epidemiology"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Leukemia%2C+Mast-Cell" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Leukemia, Mast-Cell / epidemiology"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Leukemia, Mast-Cell/epidemiology"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Leukemia, Mast-Cell/epidemiology"[MeSH]" href="#"> Add to 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aria-label="Toggle dropdown menu for keyword Receptors, Interleukin-2 / analysis" tabindex="0" aria-controls="keyword-actions-mesh-terms-33" aria-expanded="false" data-pinger-ignore> Receptors, Interleukin-2 / analysis </button><div id="keyword-actions-mesh-terms-33" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Receptors, Interleukin-2 / analysis"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Receptors%2C+Interleukin-2%2Fanalysis%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Receptors%2C+Interleukin-2%2Fanalysis%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Receptors, Interleukin-2/analysis"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Receptors, Interleukin-2 / analysis"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Receptors%2C+Interleukin-2" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Receptors, Interleukin-2 / analysis"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Receptors, Interleukin-2/analysis"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Receptors, Interleukin-2/analysis"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Retrospective Studies" tabindex="0" aria-controls="keyword-actions-mesh-terms-34" aria-expanded="false" data-pinger-ignore> Retrospective Studies </button><div id="keyword-actions-mesh-terms-34" 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class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Severity of Illness Index" tabindex="0" aria-controls="keyword-actions-mesh-terms-36" aria-expanded="false" data-pinger-ignore> Severity of Illness Index </button><div id="keyword-actions-mesh-terms-36" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Severity of Illness Index"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Severity+of+Illness+Index%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Severity+of+Illness+Index%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Severity of Illness Index"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Severity of Illness Index"> Search in PubMed </a></li><li><a class="search-in-mesh-link 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class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Biomarkers%22%5Bnm%5D&sort=date&sort_order=desc" data-href="/?term=%22Biomarkers%22%5Bnm%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&keyword="Biomarkers"[nm]" data-ga-category="search" data-ga-action="substance" data-ga-label="Biomarkers"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Biomarkers%22" data-ga-category="search_mesh" data-ga-action="substance_link" data-ga-label="Biomarkers"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Biomarkers"[nm]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Biomarkers"[nm]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword CD2 Antigens" tabindex="0" aria-controls="keyword-actions-substances-1" aria-expanded="false" data-pinger-ignore> CD2 Antigens </button><div id="keyword-actions-substances-1" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword CD2 Antigens"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22CD2+Antigens%22%5Bnm%5D&sort=date&sort_order=desc" data-href="/?term=%22CD2+Antigens%22%5Bnm%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&keyword="CD2 Antigens"[nm]" data-ga-category="search" data-ga-action="substance" data-ga-label="CD2 Antigens"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" 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Diagnostic criteria and classification of mastocytosis: a consensus proposal - PubMed