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.success-reg.overlay h2 span{font-weight:700}.newsletter-wrapper .success-reg.overlay p{border-bottom:none;color:#000;margin-top:.5rem;padding:0 .5rem .5rem}.newsletter-wrapper .err-reg.overlay .error-content{width:100%}.right .webmd-checkbox__label{margin-right:2rem}}@media only screen and (min-width:48rem){.ia-nl{min-width:46.875rem;padding-left:0}.ia-nl .newsletter-main{background-color:#edf0ff;border-radius:.25rem;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-ms-flex-direction:column;flex-direction:column;margin:1.25rem 0 1.875rem 0;min-height:0;min-width:25rem;padding:2.125rem;width:46.875rem}.ia-nl .newsletter-main .header-container{-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-orient:horizontal;-webkit-box-direction:reverse;-ms-flex-direction:row-reverse;flex-direction:row-reverse;margin-bottom:1.25rem}.ia-nl .newsletter-main .header-container .nl-header-container h3{color:#1b1b1b;font-size:1.25rem;font-weight:700;line-height:1.4;margin-bottom:12px;margin-top:0}.ia-nl .newsletter-main .header-container .nl-header-container h4{display:block!important;font-family:Source Sans Pro,Arial,sans-serif;font-size:1.125rem;font-weight:400;line-height:1.6;margin:0}.ia-nl .newsletter-main .header-container .image-container{display:block;height:8rem;overflow:inherit;width:65%}.ia-nl .newsletter-main .header-container .image-container img{border-radius:4px;border-style:none;float:right;height:8rem}.ia-nl .newsletter-main .header-container .success-reg{margin-right:1.125rem;text-align:start}.ia-nl .newsletter-main .header-container .success-reg h2{color:#1b1b1b;font-family:Source Sans Pro,Arial,sans-serif;font-size:1.25rem;font-weight:700;line-height:1.4;margin:0}.ia-nl .newsletter-main .header-container .success-reg p{border-bottom:0;color:#1b1b1b;font-family:Source Sans 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.webmd-checkbox{-webkit-box-align:center;-ms-flex-align:center;align-items:center;color:#1b1b1b;display:-webkit-box;display:-ms-flexbox;display:flex;font-size:.875rem;line-height:1.4;letter-spacing:.7px;margin-left:0!important;padding:0!important}.ia-nl .newsletter-main .content-container .series-select .webmd-checkbox__input{height:1.125rem}.ia-nl .newsletter-main .content-container .series-select .webmd-checkbox:hover{background:transparent}.ia-nl .newsletter-main .content-container .series-select .webmd-checkbox .webmd-checkbox__inner{border:2px solid #3557ff;height:1.1375rem;width:1.125rem;border-radius:.3125rem}.ia-nl .newsletter-main .content-container .series-select .webmd-checkbox.is-checked .webmd-checkbox__inner{background:url(data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iOSIgaGVpZ2h0PSI3IiBmaWxsPSJub25lIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxwYXRoIGQ9Im0xLjM4NCAzLjExNSAyLjI1IDIuMDE5IDMuNzUtNC4wMzgiIHN0cm9rZT0iIzM1NTdGRiIgc3Ryb2tlLXdpZHRoPSIyIiBzdHJva2UtbGluZWNhcD0icm91bmQiIHN0cm9rZS1saW5lam9pbj0icm91bmQiLz48L3N2Zz4=) no-repeat;background-position:50%;background-size:.5625rem}.ia-nl .newsletter-main .content-container .email-container .email-input{margin-right:0;width:100%!important}.ia-nl .newsletter-main .content-container .email-container .email-input .webmd-input__inner{border:1px solid #cccce7;border-radius:5px 0 0 5px;color:#1b1b1b;font-size:.875rem;height:45px;letter-spacing:.14px;padding:0 .75rem 0 .75rem}.ia-nl .newsletter-main .content-container .email-container button{border-radius:0 5px 5px 0;font-size:18px;font-weight:600;height:45px;line-height:1.6;padding:0 .25rem;width:25.6%}.ia-nl .newsletter-main .content-container .email-container .webmd-button--primary{background-color:#3557ff}.ia-nl .newsletter-main .content-container .email-container .webmd-button--primary:disabled{background-color:#b3b3b3;color:#676767}.ia-nl .newsletter-main .content-container .nl-disclaimer{color:#1b1b1b;font-family:Source Sans Pro,Arial,sans-serif;font-size:.75rem;line-height:1.4;padding-bottom:0}.ia-nl .newsletter-main .content-container .nl-disclaimer a{color:#3557ff}}@media only screen and (min-width:48rem)and (max-width:51.1875rem){.ia-nl{min-width:44.5rem}.ia-nl .newsletter-main{width:44.5rem}}.footer-nl-social .nl-header-container h4{display:block!important;color:#fff;font-family:Source Sans Pro,Arial,sans-serif;font-size:1.125rem;font-style:normal;font-weight:400;line-height:1.1111rem}.footer-nl-social .content-container .series-select{display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-align:start;-ms-flex-align:start;align-items:flex-start}@media only screen and (max-width:47.875rem){.footer-nl-social 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.webmd-checkbox{-webkit-box-align:center;-ms-flex-align:center;align-items:center;color:#1b1b1b;display:-webkit-box;display:-ms-flexbox;display:flex;margin-left:0!important;padding:0!important}.nlhov-content-container .series-select .webmd-checkbox__input{height:1.125rem}.nlhov-content-container .series-select .webmd-checkbox:hover{background:transparent}.nlhov-content-container .series-select .webmd-checkbox .webmd-checkbox__inner{border:2px solid #3557ff;height:1.1375rem;width:1.125rem;border-radius:5px}.nlhov-content-container .series-select .webmd-checkbox.is-checked .webmd-checkbox__inner{background:url(data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iOSIgaGVpZ2h0PSI3IiBmaWxsPSJub25lIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxwYXRoIGQ9Im0xLjM4NCAzLjExNSAyLjI1IDIuMDE5IDMuNzUtNC4wMzgiIHN0cm9rZT0iIzM1NTdGRiIgc3Ryb2tlLXdpZHRoPSIyIiBzdHJva2UtbGluZWNhcD0icm91bmQiIHN0cm9rZS1saW5lam9pbj0icm91bmQiLz48L3N2Zz4=) no-repeat;background-position:50%;background-size:.5625rem}@media only screen and (max-width:47.938em){.nlhov-content-container .series-select{display:block;margin-bottom:0}.nlhov-content-container .series-select .webmd-checkbox{padding-bottom:10px!important}}.footer-nl-social .success-reg h2{font-weight:600;line-height:50px;text-align:left}@media(max-width:47.938rem){.footer-nl-social .success-reg h2{text-align:center}}.footer-nl-social .success-reg .see-more-container{-webkit-box-align:self-start;-ms-flex-align:self-start;align-items:self-start;-webkit-box-pack:left;-ms-flex-pack:left;justify-content:left}@media(max-width:47.938rem){.footer-nl-social .success-reg .see-more-container{-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center}}.footer-nl-social .success-reg .sub-title-text{color:#fff;line-height:20px}@media(max-width:47.938rem){.footer-nl-social .success-reg .sub-title-text{-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center}}.in-art-ty h2,.right-cont h2{color:#1b1b1b;font-size:1.375rem;font-weight:700;line-height:30.8px;margin-bottom:.75rem}@media(max-width:64rem){.in-art-ty h2,.right-cont h2{font-size:2rem;line-height:42px;margin-bottom:1rem}}@media(max-width:47.938rem){.in-art-ty h2,.right-cont h2{font-size:1.5rem;line-height:33.6px;margin-bottom:.25rem}}.in-art-ty .see-more-container,.right-cont .see-more-container{-webkit-box-align:left;-ms-flex-align:left;align-items:left;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-pack:left;-ms-flex-pack:left;justify-content:left;margin-top:1rem}@media(max-width:64rem){.in-art-ty .see-more-container,.right-cont .see-more-container{margin-bottom:.75rem}}@media(max-width:47.938rem){.in-art-ty .see-more-container,.right-cont .see-more-container{-webkit-box-align:center;-ms-flex-align:center;align-items:center;-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center}}.in-art-ty .see-more-container .see-more-btn,.right-cont .see-more-container .see-more-btn{-webkit-box-align:center;-ms-flex-align:center;align-items:center;background:#3557ff;border-radius:4px;color:#fff;cursor:pointer;display:-webkit-box;display:-ms-flexbox;display:flex;font-size:1.125rem;font-weight:600;-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center;line-height:28.8px;min-width:150px;padding:8px 16px;text-decoration:none}.in-art-ty .sub-title-text,.right-cont .sub-title-text{font-size:1.125rem;line-height:28.8px}.vn-scrim:before{background:hsla(0,0%,100%,.8);content:"";height:100%;left:0;opacity:0;position:fixed;top:0;width:100%;visibility:hidden;z-index:100000;-webkit-transition:all .4s ease;transition:all .4s ease}@media(min-width:64.0625rem){.vn-scrim:before{-webkit-transition-delay:.2s;transition-delay:.2s}}.vn-scrim.vn-open:before{opacity:1;visibility:visible;-webkit-transition-delay:0s;transition-delay:0s}@media(min-width:64.0625rem){.vn-scrim.vn-open:before :not(.lite){visibility:hidden}}html body{margin-top:3rem;padding-top:0;-webkit-font-smoothing:antialiased}@media(max-width:37.5rem){html body main{margin-top:1rem}}@media(min-width:64.0625rem){html body{margin-top:0}}html.class-bg-ghost{background:#f8f8f8}.vn-typeahead-suggestions{background:#fff;border-radius:5px;-webkit-box-shadow:none;box-shadow:none;left:0!important;margin:0 8px!important;height:24.875rem;overflow:hidden;top:6.875rem!important;width:calc(100% - 1rem)}.vn-typeahead-suggestions .webmd-autocomplete-suggestion__wrap{border:0;border-radius:0}@media(min-width:64.0625rem){.vn-typeahead-suggestions.lite{top:8.625rem!important}}@media(min-width:37.5rem){.vn-typeahead-suggestions{max-width:calc(400px - 1rem)!important}}.webmd-autocomplete-suggestion{z-index:1000000!important}.vn-skip-to-main{background:#fff;border-radius:0 0 5px 5px;color:#1b1b1b;display:block;height:1.875rem;padding:.3rem;margin:0 .5rem;position:fixed;text-decoration:none;top:-100px;-webkit-transition:top .3s ease;transition:top .3s ease;z-index:100001}.vn-skip-to-main:focus{top:0}.vn-wrapper{background:#00157c;-webkit-box-sizing:border-box;box-sizing:border-box;font-family:Source Sans Pro,Arial,sans-serif;position:fixed;top:0;-webkit-transition:transform .5s ease;transition:transform .5s ease;width:100%;z-index:100000}@media(min-width:64.0625rem){.vn-wrapper.lite{padding:0 1.5rem}}.vn-wrapper.no-stick{position:relative}.vn-wrapper *{-webkit-box-sizing:border-box;box-sizing:border-box;font-family:Source Sans Pro,Arial,sans-serif;letter-spacing:normal}.vn-wrapper.vn-slide-up{-webkit-transform:translateY(-100%);transform:translateY(-100%)}@media(min-width:64.0625rem){.vn-wrapper{position:relative}}@media(max-width:81.25rem){.vn-wrapper{padding:0 1rem}}.vn-wrapper .vn-dt{display:none!important}@media(min-width:64.0625rem){.vn-wrapper .vn-dt{display:block!important}}.vn-wrapper .vn-mt{display:block}@media(min-width:64.0625rem){.vn-wrapper .vn-mt{display:none!important}}.vn-wrapper .vn-hidden{visibility:hidden!important}.vn-wrapper .vn-trans{opacity:0}.vn-wrapper .vn-none{display:none!important}@media(min-width:64.0625rem){.vn-wrapper .vn-none{display:none!important}}.vn-wrapper .vn-container{-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;height:3rem;margin:0 auto;max-width:77.5rem;z-index:1}@media(min-width:64.0625rem){.vn-wrapper .vn-container{height:4.6875rem}}.vn-wrapper .vn-container.lite{max-width:100%}@media(min-width:64.0625rem){.vn-wrapper .vn-container.lite{height:3.5rem}}.vn-wrapper .vn-menu-btn{-webkit-box-align:center;-ms-flex-align:center;align-items:center;background:none;border:0;color:#fff;cursor:pointer;display:-webkit-box;display:-ms-flexbox;display:flex;height:100%;line-height:1;padding:0}.vn-wrapper .vn-menu-btn:not(.lite){margin-right:1.166875rem}@media(min-width:64.0625rem){.vn-wrapper .vn-menu-btn:not(.lite){margin-right:0}}.vn-wrapper .vn-menu-btn i{font-size:2.25rem;width:2.25rem;overflow:hidden}.vn-wrapper .vn-menu-btn svg{fill:currentColor;pointer-events:none}.vn-wrapper .vn-menu-btn.vn-search i{font-size:1.875rem;width:1.875rem}.vn-wrapper .vn-menu-btn.vn-search:not(.lite){margin-right:0}@media(min-width:64.0625rem){.vn-wrapper .vn-menu-btn.vn-search:not(.lite) i{font-size:1.625rem;width:1.625rem}}.vn-wrapper .vn-menu-btn.vn-search.lite i{font-size:2rem;width:2rem}.vn-wrapper .vn-logo-container{-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-ms-flexbox;display:flex}.vn-wrapper .vn-logo-container .vn-logo-div{height:.9375rem;margin:0 .625rem}@media(min-width:64.0625rem){.vn-wrapper .vn-logo-container .vn-logo-div{height:1.5625rem;margin:0 1.25rem}}.vn-wrapper .vn-logo-container .vn-logo,.vn-wrapper .vn-logo-container .vn-prog-logo{line-height:1}.vn-wrapper .vn-logo-container .vn-logo img,.vn-wrapper .vn-logo-container .vn-prog-logo img{display:block;height:1.3125rem}@media(min-width:64.0625rem){.vn-wrapper .vn-logo-container .vn-logo img,.vn-wrapper .vn-logo-container .vn-prog-logo img{height:1.625rem}.vn-wrapper .vn-logo-container .vn-logo img:not(.lite){width:7.25rem}}.vn-wrapper .vn-logo-container.with-program .vn-logo img{height:.875rem}@media(min-width:64.0625rem){.vn-wrapper .vn-logo-container.with-program .vn-logo img{height:1.4375rem}}.vn-wrapper .vn-logo-container.with-program .vn-prog-logo img{height:.9375rem}@media(min-width:64.0625rem){.vn-wrapper .vn-logo-container.with-program .vn-prog-logo img{height:1.5625rem}}.vn-wrapper .vn-links{background:#f9f9fc;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-ms-flex-direction:column;flex-direction:column;height:calc(100vh - 3rem);left:-140vw;overflow:auto;padding:.5rem;position:fixed;top:3rem;-webkit-transition:left .5s ease;transition:left .5s ease;width:100%;z-index:100}@media(min-width:37.5rem){.vn-wrapper .vn-links{max-width:25rem}}@media(min-width:64.0625rem){.vn-wrapper .vn-links.lite{height:calc(100vh - 3.5rem);top:3.5rem}.vn-wrapper .vn-links:not(.lite){background:none;-webkit-box-orient:horizontal;-webkit-box-direction:normal;-ms-flex-direction:row;flex-direction:row;height:100%;left:0;max-width:100%;overflow:visible;padding:0;position:relative;top:0}}.vn-wrapper .vn-links.open{left:0}.vn-wrapper .vn-links.open.vn-slide-out{left:-100vw}@media(min-width:37.5rem){.vn-wrapper .vn-links.open.vn-slide-out{left:0}}.vn-wrapper .vn-links .vn-search-wrapper{display:-webkit-box;display:-ms-flexbox;display:flex;height:3rem;margin-bottom:.25rem;-webkit-box-ordinal-group:0;-ms-flex-order:-1;order:-1}@media(min-width:64.0625rem){.vn-wrapper .vn-links .vn-search-wrapper:not(.lite){background:#fff;border:1px solid #c6cedb;border-radius:5px;opacity:0;-webkit-box-ordinal-group:2;-ms-flex-order:1;order:1;position:absolute;right:2.8125rem;top:.8125rem;width:38%;-webkit-transition:all .3s ease;transition:all .3s ease;visibility:hidden}.vn-wrapper .vn-links .vn-search-wrapper:not(.lite).vn-open{visibility:visible;opacity:1}.vn-wrapper .vn-links .vn-search-wrapper:not(.lite) input{border:0;height:2.8125rem}}.vn-wrapper .vn-links .vn-search-wrapper>div{-webkit-box-flex:1;-ms-flex-positive:1;flex-grow:1}.vn-wrapper .vn-links .vn-search-wrapper>div>div{width:100%}.vn-wrapper .vn-links .vn-search-wrapper input{border:1px solid #cccce7;border-right:0;border-radius:5px 0 0 5px;-webkit-box-flex:1;-ms-flex-positive:1;flex-grow:1;font-size:1.125rem;height:3rem;padding:0 1.375rem}.vn-wrapper .vn-links .vn-search-wrapper input::-webkit-input-placeholder{color:#7f888f}.vn-wrapper .vn-links .vn-search-wrapper input::-moz-placeholder{color:#7f888f}.vn-wrapper .vn-links .vn-search-wrapper 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Full Guide </a></li></ul></div></div><span data-v-1313202e></span></section></div><div class="webmd-row pane" style="" id="ContentPane30" tabindex="-1"><article class="article medref" data-chronicle="091e9c5e81e4bc93" data-e2e="dart-medref" data-page="1" data-module-type="dynamic-article" data-artid="091e9c5e81f065d0" style=""><script type="application/ld+json"></script><script type="application/ld+json"></script><div class="inner-article-container"><header><h1>Graviola for Cancer: What We Know </h1></header><div class="med-wrap"><div><div class="asset-med-rev"><div class="reviewer-info" data-chronicle="091e9c5e81e4bc93" data-e2e="asset-medical-review" data-metrics-module="rvdby-lnk"><span class="reviewer-photo-cont"><figure><img src="https://img.lb.wbmdstatic.com/vim/live/webmd/consumer_assets/site_images/articles/biographies/sheikh_zilpah_382x382.jpg?resize=51px:51px&output-quality=75" class="reviewer-photo"></figure></span><span class="seperatorLine reviewer-txt">Medically Reviewed by <a class="person" href="https://www.webmd.com/bio/zilpah-sheikh" data-metrics-link="0">Zilpah Sheikh, MD</a><span class="no-link"></span><span class="revDate"> on April 20, 2024</span></span></div><div class="byline"><span><span class="authors" data-metrics-module="wrtnby-lnk">Written by <span class="person">Linda Rath</span>, <a href="https://www.webmd.com/bio/shawna-seed" class="person" data-metrics-link="0">Shawna Seed</a></span></span></div></div></div></div><aside class="oncology-article-nav" data-metrics-module="cwnav-art"><ul class="nav-items desktop"><li><a href="#091e9c5e81f065d0-1-2">Graviola and Cancer</a></li><li><a href="#091e9c5e81f065d0-2-4">Graviola and Cancer Research</a></li><li><a href="#091e9c5e81f065d0-2-5">Potential Risks of Graviola for Cancer</a></li><li><a href="#091e9c5e81f065d0-3-6">Where to Find Graviola </a><div class="item-button"><a href="#"></a></div></li><li><a href="#091e9c5e81f065d0-3-8">How Much Graviola Is Safe?</a></li><li><a href="#091e9c5e81f065d0-3-9">Graviola Takeaways</a></li><li><a href="#091e9c5e81f065d0-3-10">Graviola FAQs</a></li><li class="item-button"></li></ul></aside><div class="reading-wrapper"><div class="readtime"><span>5 min read</span></div><div id="audio-placeholder-091e9c5e81f065d0"></div></div><div class="article__body" data-metrics-module="embd-lnk"><div class="article-page active-page" data-page="1"><section><p>Graviola (<i>Annona muricata</i>), also called soursop, is a fruit tree that grows in tropical rainforests. It's also called guanabana and Brazilian paw paw. People have long used its fruit, roots, seeds, and leaves to treat all kinds of ailments, including cancer. The fruit is dark green and prickly. Graviola also is available in capsules, tablets, and powders.</p><p>Modern scientists have been studying the plant for 50 years. They see potential promise in graviola. Animal studies have shown graviola might have a future in diabetes treatment. It also has shown antiviral, anti-inflammatory, and pain-relieving properties. </p><p>Studies have found it kills cancer cells in test tubes and in animal studies. But scientists don’t yet know whether it works as a treatment for <a class="" href="https://www.webmd.com/cancer/understanding-cancer-symptoms" id="884a37a1-f1ac-4c89-99cc-5067949c800a;medical_reference">cancer</a> in humans.</p></section><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-1-2">Graviola and Cancer</h2><p>Graviola contains hundreds of chemicals called acetogenins (ACGs). In lab tests, ACGs kill many types of cancer cells without harming healthy ones. They can treat tumors that haven’t responded to cancer medicines. </p><p>ACGs seem to work in different ways to kill, block, or otherwise fight different types of cancers. The pathways include:</p></section><section> <p><strong>Cell death. </strong>Normally, old or damaged cells die naturally, a process called apoptosis. Cancerous cells often find a way to dodge this and to survive. Graviola leaf extracts may force cancer cells to go through normal cell death. More research is needed to determine whether graviola is an effective and safe cancer treatment. </p><p><strong>Block metastasis. </strong>This is another name for<strong></strong>a cancer spread. Lab studies found that graviola extracts stopped cancer cells from growing and metastasizing.</p><p><strong>Scramble signals. </strong>Cells receive messages from inside and outside the cell. Signaling pathways relay the messages. A mistake in one of these pathways can lead to cancer. Graviola blocks pathways that control the growth and life cycle of cancer cells.</p><p><strong>ATP. </strong>Every cell in your body uses a compound called adenosine triphosphate (ATP) for energy. When graviola blocks ATP in cancer cells, the cells die.</p><p>You shouldn’t use graviola in place of your regular cancer therapy. If you’d like to add it to medicine you already take, talk to your doctor.</p></section></div><div class="article-page " data-page="2"><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-2-4">Graviola and Cancer Research</h2><p>Scientists have studied graviola for many kinds of cancers. Findings from lab and animal studies have been encouraging. But they haven’t tested graviola on people to know if the results will hold up. </p><p><strong>Breast cancer. </strong>In one study, graviola leaf extract shrank breast tumors in mice. Other studies looked at the effect of graviola fruit extract on a protein called epidermal growth factor receptor (EGFR). This protein sits on the surface of cells and helps them grow and divide. Some breast cancer cells have too much EGFR. The cells grow faster and are harder to treat. Graviola blocked the growth of these cells.</p><p><strong>Liver cancer. </strong>In several studies, graviola extract caused cell death in liver cancer cells.</p><p><strong>Lung cancer. </strong>Graviola leaf extract stopped the growth cycle of <a href="https://www.webmd.com/lung-cancer/understanding-lung-cancer-symptoms">lung cancer</a> cells. </p><p><strong>Pancreatic cancer. </strong>A powder of graviola leaves and stems caused cell death in pancreatic cancer cells. Graviola also blocked signaling pathways that help pancreatic tumors spread.</p><p><strong>Prostate cancer.</strong> In studies, graviola fruit pulp extract stopped prostate cancer cells from spreading.</p><p><strong>Colon cancer.</strong> One study found that an extract from graviola leaves killed colon cancer cells in the lab.</p><p><strong>Skin cancer. </strong>An extract from graviola leaves inhibited tumor growth in a study of mice with skin cancer.</p><p> </p><p> </p></section><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-2-5">Potential Risks of Graviola for Cancer</h2><p>People in South America and Africa use graviola for food and medicine. No one knows the best dose or how much is safe. Possible harms from graviola may include:</p><p><strong>Nerve damage</strong>. Some lab animals got tremors and other movement problems similar to symptoms of Parkinson’s disease. </p><p><strong>Low blood pressure. </strong>Graviola could lead to a drop in blood pressure in animals and humans. This may cause trouble if you already have low blood pressure or on medication to lower it.</p><p><strong>Low blood sugar. </strong>Graviola potentially may be dangerous if you’re prone to low blood sugar (hypoglycemia) or take <a class="" href="https://www.webmd.com/diabetes/type-2-diabetes" id="9620d286-a8c3-4101-a43a-280d36dc3a7f;medical_reference">diabetes</a> drugs.</p><p><strong>Faulty tests. </strong>Graviola can interfere with nuclear imaging because it stops your body from absorbing the radioactive drugs used in the test. It also might interfere with your blood pressure reading or blood sugar level tests.</p><p>If you take a large dose of graviola at one time, it might cause nausea and vomiting.</p><p> </p></section></div><div class="article-page " data-page="3"><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-3-6">Where to Find Graviola </h2><p>You can buy graviola fruit powder, leaf or stem powder, and pulp extract from health food stores and other retail outlets. It's also sold as a tea made from the leaves.</p></section><section><pagebreak /> <p> In some places, you can find graviola fruit in the produce section of markets. You can plant the trees and harvest your own fruit in some parts of Florida, although the tree isn't native to the United States. </p><p>The fruit has a consistency similar to custard. The taste is often described as a combination of apple and strawberry. People use the fruit in smoothies, juices, and ice cream.</p></section><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-3-8">How Much Graviola Is Safe?</h2><p>The fruit is safe to eat. Avoid the seeds, however, because they can be toxic.</p><p>Graviola food and drinks are generally fine when you add them as a normal part of your diet.</p><p>Dietary supplements in forms such as pills, tablets, powders, and liquids are regulated by the FDA. However, the FDA doesn't make rules for supplements the way it does for drugs. It doesn't establish recommended doses, for instance. </p></section><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-3-9">Graviola Takeaways</h2><p>Graviola is a tropical fruit also called soursop, guanabana, or Brazilian paw paw. People have long used the fruit, leaves, and bark in traditional healing. Research has shown that it has anti-diabetic, antiviral, and anti-inflammatory properties. It's often touted as a cancer treatment. Studies in test tubes and on animals have shown some potential in treating cancers of the breast, prostate, liver, lung, pancreas, colon, and skin. However, it's not clear whether those lab results would carry over to humans. It's generally safe to eat graviola as part of a normal diet. You also can find it as a dietary supplement in the form of powders, tablets, and pills. There's no recommended dose of graviola as a dietary supplement. If you're thinking of taking graviola – especially if you have cancer – it's important to check with your doctor first. </p></section><section><h2 class="jumplink-headers" id="091e9c5e81f065d0-3-10">Graviola FAQs</h2><p><strong>What does graviola do for the body?</strong></p><p>Animal and lab studies have found that compounds in graviola may have cancer-fighting abilities. Traditionally, it's been used to treat digestion problems, fevers, insomnia, and infections. Some studies have suggest it might help fight diabetes and treat ulcers. But we don't know enough about how it works in humans to say for sure whether it's beneficial. </p></section></div><div class="article-page " data-page="4"><section> <p><strong>Who should not take graviola?</strong></p><p>Talk to your doctor before taking graviola, especially if: </p><ul><li>You take medicine to lower your blood sugar.</li><li>You take medicine to lower your blood pressure.</li><li>You have an imaging test, such as a <a class="" href="https://www.webmd.com/a-to-z-guides/pet-scan" id="2e33e69d-f57d-426f-8ee8-dd2f71f02128;medical_reference">PET scan</a>, coming up.</li></ul><p><strong>Who should not drink soursop tea?</strong></p><p>It's not clear whether graviola, or soursop, tea is safe for pregnant women. There's not enough information to say whether it is safe for young children. You should avoid using the tea for long periods of time.</p><p><strong>Is graviola a superfood?</strong></p><p>There's no official definition of a superfood. Generally, it means a food is low in calories and also packed with nutrients such as antioxidants, minerals, and vitamins. Superfoods also may be rich in fiber, flavonoids, and healthy fats.</p><p>One cup of raw graviola contains: </p><ul><li>Calories: 148</li><li>Dietary fiber: 7.42 grams</li><li>Protein: 2.25 grams </li><li>Carbs: 37.8 grams</li><li>Sugar: 30 grams</li></ul><p>It also contains potassium, magnesium, vitamin C, and <a class="" href="https://www.webmd.com/diet/health-benefits-antioxidants" id="4f223887-caba-4c06-ad0b-1aee7b9d2007;medical_reference">antioxidants</a>.</p></section></div></div><div class="related-articles" data-metrics-module="cwnav-art" data-metrics-sel="li"><ul class="related-items"><span>RELATED ARTICLES:</span><li><a href="https://www.webmd.com/cancer/cancer-natural-remedies-side-effects">Natural Remedies for Treatment Side Effects</a></li><li><a href="https://www.webmd.com/cancer/cancer-holistic-care-limits">Holistic Cancer Treatment</a></li><li><a href="https://www.webmd.com/cancer/amygdalin-cancer-treatment">Is Amygdalin a Safe Cancer Treatment?</a></li><li><a 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5H17C17.85 5 18.5625 5.2875 19.1375 5.8625C19.7125 6.4375 20 7.15 20 8V14H16V18ZM18 12V8C18 7.71667 17.9042 7.47917 17.7125 7.2875C17.5208 7.09583 17.2833 7 17 7H3C2.71667 7 2.47917 7.09583 2.2875 7.2875C2.09583 7.47917 2 7.71667 2 8V12H4V10H16V12H18Z" fill="#3557FF" data-v-00aa1eb2></path></svg></div></div></div><div class="save-container"><div class="auth-overlay-popup-holder" data-v-28242611><div class="bookmark-holder drug-generic-name" data-metrics-module="bkmk" data-v-28242611></div></div></div></div></div><div class="asset-footer-content"><div style="display:none;" class="sources-section"><div class="sources-wrapper" data-metrics-module="src"><p>SOURCES:</p><p><i>Oxidative Medicine and Cellular Longevity:</i> “Anticancer Properties of Graviola (<i>Annona muricata</i>): A Comprehensive Mechanistic Review.”</p><p><i>Carcinogenesis:</i> “Emerging therapeutic potential of graviola and its constituents in cancer.”</p><p>Cancerresearchuk.org: “Graviola (soursop).”</p><p><i>The Malaysian Journal of Medical Sciences:</i> “Potential Benefits of <i>Annona muricata</i> in Combating Cancer: A Review.”</p><p><i>Cancer Letters:</i> “The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells,” “Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells <i>in vitro</i> and <i>in vivo</i> through altering cell metabolism.”</p><p><i>BMC Complementary Medicine and Therapies:</i> “Anti-cancer effect of Annona Muricata Linn Leaves Crude Extract (AMCE) on breast cancer cell line.”</p><p><i>Nutrition and Cancer</i>: “Selective Growth Inhibition of Human Breast Cancer Cells by Graviola Fruit Extract in Vitro and in Vivo Involving Downregulation of EGFR Expression.”</p><p>Memorial Sloan-Kettering Cancer Center: “Graviola.”</p><p><i>Advances in Breast Cancer Research:</i> “Patient with Metastatic Breast Cancer Achieves Stable Disease for 5 Years on Graviola and Xeloda after Progressing on Multiple Lines of Therapy.”</p><p><i>Journal of Human Hypertension:</i> “The effects of soursop supplementation on blood pressure, serum uric acid, and kidney function in a prehypertensive population in accordance with the 2017 ACC/AHA guideline.”</p><p><i>Journal of Ethnopharmacology: "</i>Annona muricata leaves induce G₁ cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells."</p><p><i>Asian Pacific Journal of Cancer Prevention:</i> "Chemopreventive potential of Annona muricata L leaves on chemically-induced skin papillomagenesis in mice."</p><p>Cancer Association of South Africa: "Fact Sheet and Position Statement on Soursop (Graviola)."</p><p>University of Texas-El Paso: "Herbal Safety: Soursop."</p><p>University of Florida Gardening Solutions: "Sweetsop, Soursop, and Atemoya."</p><p>FDA.gov: "Questions and Answers on Dietary Supplements." </p><p>Cleveland Clinic: "What Is a Superfood, Anyway?" 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It's also called guanabana and Brazilian paw paw. People have long used its fruit, roots, seeds, and leaves to treat all kinds of ailments, including cancer. The fruit is dark green and prickly. Graviola also is available in capsules, tablets, and powders.\u003C\u002Fp\u003E\u003Cp\u003EModern scientists have been studying the plant for 50 years. They see potential promise in graviola. Animal studies have shown graviola might have a future in diabetes treatment. It also has shown antiviral, anti-inflammatory, and pain-relieving properties. \u003C\u002Fp\u003E\u003Cp\u003EStudies have found it kills cancer cells in test tubes and in animal studies. But scientists don’t yet know whether it works as a treatment for \u003Ca class=\"\" link_friendlyurl=\"https:\u002F\u002Fwww.webmd.com\u002Fcancer\u002Funderstanding-cancer-symptoms\" id=\"884a37a1-f1ac-4c89-99cc-5067949c800a;medical_reference\"\u003Ecancer\u003C\u002Fa\u003E in humans.\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Csection_header\u003EGraviola and Cancer\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EGraviola contains hundreds of chemicals called acetogenins (ACGs). In lab tests, ACGs kill many types of cancer cells without harming healthy ones. They can treat tumors that haven’t responded to cancer medicines. \u003C\u002Fp\u003E\u003Cp\u003EACGs seem to work in different ways to kill, block, or otherwise fight different types of cancers. The pathways include:\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"2\" \u002F\u003E\u003Csection_header is_continued=\"true\"\u003EGraviola and Cancer continued...\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003E\u003Cstrong\u003ECell death. \u003C\u002Fstrong\u003ENormally, old or damaged cells die naturally, a process called apoptosis. Cancerous cells often find a way to dodge this and to survive. Graviola leaf extracts may force cancer cells to go through normal cell death. More research is needed to determine whether graviola is an effective and safe cancer treatment. \u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EBlock metastasis. \u003C\u002Fstrong\u003EThis is another name for\u003Cstrong\u003E\u003C\u002Fstrong\u003Ea cancer spread. Lab studies found that graviola extracts stopped cancer cells from growing and metastasizing.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EScramble signals. \u003C\u002Fstrong\u003ECells receive messages from inside and outside the cell. Signaling pathways relay the messages. A mistake in one of these pathways can lead to cancer. Graviola blocks pathways that control the growth and life cycle of cancer cells.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EATP. \u003C\u002Fstrong\u003EEvery cell in your body uses a compound called adenosine triphosphate (ATP) for energy. When graviola blocks ATP in cancer cells, the cells die.\u003C\u002Fp\u003E\u003Cp\u003EYou shouldn’t use graviola in place of your regular cancer therapy. If you’d like to add it to medicine you already take, talk to your doctor.\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"3\" \u002F\u003E\u003Cpagebreak type=\"desktop\" order=\"2\" \u002F\u003E\u003Csection_header\u003EGraviola and Cancer Research\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EScientists have studied graviola for many kinds of cancers. Findings from lab and animal studies have been encouraging. But they haven’t tested graviola on people to know if the results will hold up. \u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EBreast cancer. \u003C\u002Fstrong\u003EIn one study, graviola leaf extract shrank breast tumors in mice. Other studies looked at the effect of graviola fruit extract on a protein called epidermal growth factor receptor (EGFR). This protein sits on the surface of cells and helps them grow and divide. Some breast cancer cells have too much EGFR. The cells grow faster and are harder to treat. Graviola blocked the growth of these cells.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ELiver cancer. \u003C\u002Fstrong\u003EIn several studies, graviola extract caused cell death in liver cancer cells.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ELung cancer. \u003C\u002Fstrong\u003EGraviola leaf extract stopped the growth cycle of \u003Ca link_friendlyurl=\"https:\u002F\u002Fwww.webmd.com\u002Flung-cancer\u002Funderstanding-lung-cancer-symptoms\"\u003Elung cancer\u003C\u002Fa\u003E cells. \u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EPancreatic cancer. \u003C\u002Fstrong\u003EA powder of graviola leaves and stems caused cell death in pancreatic cancer cells. Graviola also blocked signaling pathways that help pancreatic tumors spread.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EProstate cancer.\u003C\u002Fstrong\u003E In studies, graviola fruit pulp extract stopped prostate cancer cells from spreading.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EColon cancer.\u003C\u002Fstrong\u003E One study found that an extract from graviola leaves killed colon cancer cells in the lab.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ESkin cancer. \u003C\u002Fstrong\u003EAn extract from graviola leaves inhibited tumor growth in a study of mice with skin cancer.\u003C\u002Fp\u003E\u003Cp\u003E \u003C\u002Fp\u003E\u003Cp\u003E \u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"4\" \u002F\u003E\u003Csection_header\u003EPotential Risks of Graviola for Cancer\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EPeople in South America and Africa use graviola for food and medicine. No one knows the best dose or how much is safe. Possible harms from graviola may include:\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ENerve damage\u003C\u002Fstrong\u003E. Some lab animals got tremors and other movement problems similar to symptoms of Parkinson’s disease. \u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ELow blood pressure. \u003C\u002Fstrong\u003EGraviola could lead to a drop in blood pressure in animals and humans. This may cause trouble if you already have low blood pressure or on medication to lower it.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003ELow blood sugar. \u003C\u002Fstrong\u003EGraviola potentially may be dangerous if you’re prone to low blood sugar (hypoglycemia) or take \u003Ca class=\"\" link_friendlyurl=\"https:\u002F\u002Fwww.webmd.com\u002Fdiabetes\u002Ftype-2-diabetes\" id=\"9620d286-a8c3-4101-a43a-280d36dc3a7f;medical_reference\"\u003Ediabetes\u003C\u002Fa\u003E drugs.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EFaulty tests. \u003C\u002Fstrong\u003EGraviola can interfere with nuclear imaging because it stops your body from absorbing the radioactive drugs used in the test. It also might interfere with your blood pressure reading or blood sugar level tests.\u003C\u002Fp\u003E\u003Cp\u003EIf you take a large dose of graviola at one time, it might cause nausea and vomiting.\u003C\u002Fp\u003E\u003Cp\u003E \u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"desktop\" order=\"3\" \u002F\u003E\u003Csection_header\u003EWhere to Find Graviola \u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EYou can buy graviola fruit powder, leaf or stem powder, and pulp extract from health food stores and other retail outlets. It's also sold as a tea made from the leaves.\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"5\" \u002F\u003E\u003Cpagebreak \u002F\u003E\u003Csection_header is_continued=\"true\"\u003EWhere to Find Graviola continued...\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003E In some places, you can find graviola fruit in the produce section of markets. You can plant the trees and harvest your own fruit in some parts of Florida, although the tree isn't native to the United States. \u003C\u002Fp\u003E\u003Cp\u003EThe fruit has a consistency similar to custard. The taste is often described as a combination of apple and strawberry. People use the fruit in smoothies, juices, and ice cream.\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Csection_header\u003EHow Much Graviola Is Safe?\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EThe fruit is safe to eat. Avoid the seeds, however, because they can be toxic.\u003C\u002Fp\u003E\u003Cp\u003EGraviola food and drinks are generally fine when you add them as a normal part of your diet.\u003C\u002Fp\u003E\u003Cp\u003EDietary supplements in forms such as pills, tablets, powders, and liquids are regulated by the FDA. However, the FDA doesn't make rules for supplements the way it does for drugs. It doesn't establish recommended doses, for instance. \u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"6\" \u002F\u003E\u003Csection_header\u003EGraviola Takeaways\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003EGraviola is a tropical fruit also called soursop, guanabana, or Brazilian paw paw. People have long used the fruit, leaves, and bark in traditional healing. Research has shown that it has anti-diabetic, antiviral, and anti-inflammatory properties. It's often touted as a cancer treatment. Studies in test tubes and on animals have shown some potential in treating cancers of the breast, prostate, liver, lung, pancreas, colon, and skin. However, it's not clear whether those lab results would carry over to humans. It's generally safe to eat graviola as part of a normal diet. You also can find it as a dietary supplement in the form of powders, tablets, and pills. There's no recommended dose of graviola as a dietary supplement. If you're thinking of taking graviola – especially if you have cancer – it's important to check with your doctor first. \u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Csection_header\u003EGraviola FAQs\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003E\u003Cstrong\u003EWhat does graviola do for the body?\u003C\u002Fstrong\u003E\u003C\u002Fp\u003E\u003Cp\u003EAnimal and lab studies have found that compounds in graviola may have cancer-fighting abilities. Traditionally, it's been used to treat digestion problems, fevers, insomnia, and infections. Some studies have suggest it might help fight diabetes and treat ulcers. But we don't know enough about how it works in humans to say for sure whether it's beneficial. \u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E\u003Csection_group\u003E\u003Cpagebreak type=\"mobile\" order=\"7\" \u002F\u003E\u003Cpagebreak type=\"desktop\" order=\"4\" \u002F\u003E\u003Csection_header is_continued=\"true\"\u003EGraviola FAQs continued...\u003C\u002Fsection_header\u003E\u003Csection_text\u003E\u003Cp\u003E\u003Cstrong\u003EWho should not take graviola?\u003C\u002Fstrong\u003E\u003C\u002Fp\u003E\u003Cp\u003ETalk to your doctor before taking graviola, especially if: \u003C\u002Fp\u003E\u003Cul\u003E\u003Cli\u003EYou take medicine to lower your blood sugar.\u003C\u002Fli\u003E\u003Cli\u003EYou take medicine to lower your blood pressure.\u003C\u002Fli\u003E\u003Cli\u003EYou have an imaging test, such as a \u003Ca class=\"\" link_friendlyurl=\"https:\u002F\u002Fwww.webmd.com\u002Fa-to-z-guides\u002Fpet-scan\" id=\"2e33e69d-f57d-426f-8ee8-dd2f71f02128;medical_reference\"\u003EPET scan\u003C\u002Fa\u003E, coming up.\u003C\u002Fli\u003E\u003C\u002Ful\u003E\u003Cp\u003E\u003Cstrong\u003EWho should not drink soursop tea?\u003C\u002Fstrong\u003E\u003C\u002Fp\u003E\u003Cp\u003EIt's not clear whether graviola, or soursop, tea is safe for pregnant women. There's not enough information to say whether it is safe for young children. You should avoid using the tea for long periods of time.\u003C\u002Fp\u003E\u003Cp\u003E\u003Cstrong\u003EIs graviola a superfood?\u003C\u002Fstrong\u003E\u003C\u002Fp\u003E\u003Cp\u003EThere's no official definition of a superfood. Generally, it means a food is low in calories and also packed with nutrients such as antioxidants, minerals, and vitamins. Superfoods also may be rich in fiber, flavonoids, and healthy fats.\u003C\u002Fp\u003E\u003Cp\u003EOne cup of raw graviola contains: \u003C\u002Fp\u003E\u003Cul\u003E\u003Cli\u003ECalories: 148\u003C\u002Fli\u003E\u003Cli\u003EDietary fiber: 7.42 grams\u003C\u002Fli\u003E\u003Cli\u003EProtein: 2.25 grams \u003C\u002Fli\u003E\u003Cli\u003ECarbs: 37.8 grams\u003C\u002Fli\u003E\u003Cli\u003ESugar: 30 grams\u003C\u002Fli\u003E\u003C\u002Ful\u003E\u003Cp\u003EIt also contains potassium, magnesium, vitamin C, and \u003Ca class=\"\" link_friendlyurl=\"https:\u002F\u002Fwww.webmd.com\u002Fdiet\u002Fhealth-benefits-antioxidants\" id=\"4f223887-caba-4c06-ad0b-1aee7b9d2007;medical_reference\"\u003Eantioxidants\u003C\u002Fa\u003E.\u003C\u002Fp\u003E\u003C\u002Fsection_text\u003E\u003Chighlights\u003E\u003C\u002Fhighlights\u003E\u003Cpull_quotes\u003E\u003C\u002Fpull_quotes\u003E\u003C\u002Fsection_group\u003E"},"citations":{"#cdata-section":"\u003Cp\u003ESOURCES:\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EOxidative Medicine and Cellular Longevity:\u003C\u002Fi\u003E “Anticancer Properties of Graviola (\u003Ci\u003EAnnona muricata\u003C\u002Fi\u003E): A Comprehensive Mechanistic Review.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003ECarcinogenesis:\u003C\u002Fi\u003E “Emerging therapeutic potential of graviola and its constituents in cancer.”\u003C\u002Fp\u003E\u003Cp\u003ECancerresearchuk.org: “Graviola (soursop).”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EThe Malaysian Journal of Medical Sciences:\u003C\u002Fi\u003E “Potential Benefits of \u003Ci\u003EAnnona muricata\u003C\u002Fi\u003E in Combating Cancer: A Review.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003ECancer Letters:\u003C\u002Fi\u003E “The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells,” “Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells \u003Ci\u003Ein vitro\u003C\u002Fi\u003E and \u003Ci\u003Ein vivo\u003C\u002Fi\u003E through altering cell metabolism.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EBMC Complementary Medicine and Therapies:\u003C\u002Fi\u003E “Anti-cancer effect of Annona Muricata Linn Leaves Crude Extract (AMCE) on breast cancer cell line.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003ENutrition and Cancer\u003C\u002Fi\u003E: “Selective Growth Inhibition of Human Breast Cancer Cells by Graviola Fruit Extract in Vitro and in Vivo Involving Downregulation of EGFR Expression.”\u003C\u002Fp\u003E\u003Cp\u003EMemorial Sloan-Kettering Cancer Center: “Graviola.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EAdvances in Breast Cancer Research:\u003C\u002Fi\u003E “Patient with Metastatic Breast Cancer Achieves Stable Disease for 5 Years on Graviola and Xeloda after Progressing on Multiple Lines of Therapy.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EJournal of Human Hypertension:\u003C\u002Fi\u003E “The effects of soursop supplementation on blood pressure, serum uric acid, and kidney function in a prehypertensive population in accordance with the 2017 ACC\u002FAHA guideline.”\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EJournal of Ethnopharmacology: \"\u003C\u002Fi\u003EAnnona muricata leaves induce G₁ cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells.\"\u003C\u002Fp\u003E\u003Cp\u003E\u003Ci\u003EAsian Pacific Journal of Cancer Prevention:\u003C\u002Fi\u003E \"Chemopreventive potential of Annona muricata L leaves on chemically-induced skin papillomagenesis in mice.\"\u003C\u002Fp\u003E\u003Cp\u003ECancer Association of South Africa: \"Fact Sheet and Position Statement on Soursop (Graviola).\"\u003C\u002Fp\u003E\u003Cp\u003EUniversity of Texas-El Paso: \"Herbal Safety: Soursop.\"\u003C\u002Fp\u003E\u003Cp\u003EUniversity of Florida Gardening Solutions: \"Sweetsop, Soursop, and Atemoya.\"\u003C\u002Fp\u003E\u003Cp\u003EFDA.gov: \"Questions and Answers on Dietary Supplements.\" \u003C\u002Fp\u003E\u003Cp\u003ECleveland Clinic: \"What Is a Superfood, Anyway?\" \"What Is Soursop?\" \u003C\u002Fp\u003E"},"related_links_header":"","related_links_text":{"#cdata-section":""}}}}}},"staticPublicPath":"\u002Fstatic_vue\u002F091e9c5e81e4bc92\u002Fclient\u002F","isInteractivePage":false},"flow":{"flowInfo":{"legacyBundleArticle":{"assetId":"091e9c5e81f03cae","ctgryTitle":"Graviola for Cancer Treatment","ctgryUrl":"https:\u002F\u002Fwww.webmd.com\u002Fcancer\u002Frick-simpson-oil-for-cancer-overview","channelId":"1022","category":"bndl","contentType":"Article"}}},"quiz":{"rmq":{}}}</script> <script>window.__INITIAL_STATE__.route.hash = window.location.hash; 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