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class="container"> <div class="row"> <div class="col-lg-12"> <h1>Human-relevant Models</h1> <ul> <h2 class="element-invisible">You are here</h2><div class="breadcrumb"><span class="inline odd first"><a href="/">Home</a></span> <span class="delimiter">»</span> <span class="inline even"><a href="/research/research">Research</a></span> <span class="delimiter">»</span> <span class="inline odd last"><a href="/research/bioengineering">Bioengineering</a></span></div> </ul> </div> </div> </div> </section> <div class="container"> </div> <section> <div class="container"> <div class="row"> <div class="col-md-8 col-lg-8 main-content"> <div id="node-1164" class="node node-research-topic clearfix" about="/research/human-relevant-models" typeof="sioc:Item foaf:Document"> <div class="content margin-bottom-10px"> <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><h2 class="rtecenter"><img alt="" src="/sites/default/files/ivm_group_group21_nov_jpeg_1.jpg" style="height:450px; width:800px" /></h2> <h2 class="rtecenter"><strong>Human-Relevant Models Group</strong></h2> <p class="rtejustify">Our research is centered on the development of physiologically relevant <em>human-based</em> models at the milli, micro and nanoscale for application to disease models, tissue engineering, toxicity testing, and as <a href="https://www.centro3r.it/">alternatives to animal experimentation</a>. To achive this goal we use an integrated approach, based on:</p> <h3 class="rtecenter"><a href="http://www.centropiaggio.unipi.it/research/vitro-models"><em>In vitro</em> Models</a><img alt="" src="/sites/default/files/pictures/invitroinsilico.png" style="height:276px; width:400px" /><a href="http://www.centropiaggio.unipi.it/research/silico-models"><em>In silico</em> Models</a></h3> <table border="1" cellpadding="1" cellspacing="1" class="table-bordered" style="height:109px; width:782px"> <tbody> <tr> <td class="rtecenter"> <p><span style="font-size:12px"><big>Advanced In-vitro Models are engineered combining biofabrication, bioreactors, biomimetic and smart materials with the aim of mimicking tissue architecure, biomechanics and dynamic conditions.</big></span></p> </td> <td> <p class="rtecenter"><span style="font-size:12px"><big>Computational and analytical tools are used to model and design living systems, </big></span><span style="font-size:12px"><big>mimicking natural intelligence in silico.</big></span></p> </td> </tr> </tbody> </table> <p class="rtecenter"> </p> <p> </p> <h2 class="rtecenter"><strong>Human-Relevant Model People</strong></h2> <p class="rtecenter"><a href="http://www.centropiaggio.unipi.it/~ahluwalia">Arti AHLUWALIA</a>, Full Professor</p> <p class="rtecenter"><a href="http://www.centropiaggio.unipi.it/~magliaro">Chiara MAGLIARO</a>, Assistant Professor</p> <p class="rtecenter"><a href="http://www.centropiaggio.unipi.it/~cacopardo">Ludovica CACOPARDO</a>, RTDA Researcher</p> <p class="rtecenter"><a href="http://www.centropiaggio.unipi.it/~botte">Ermes BOTTE</a>, PhD Student</p> <p class="rtecenter"><a href="http://www.centropiaggio.unipi.it/~nicoleguazzelli">Nicole GUAZZELLI</a>, PhD Student</p> <p class="rtecenter">Piera MANCINI, PhD Student</p> <p class="rtecenter">Rachele FABBRI, PhD Student</p> <div> <h2> </h2> <h2><strong>Current Research Projects</strong></h2> <p class="rtejustify"><a href="http://www.centropiaggio.unipi.it/projects/patrols-physiologically-anchored-tools-realistic-nanomaterial-hazard-assessment.html"><strong>PATROLS</strong></a>: Development of advanced safety assessment tools for improved prediction of the adverse effects caused by chronic ENM - Engineered Nano-Materials - exposure in human and environmental systems.</p> <p class="rtejustify"><strong>ORGANOMICS</strong>: Integration of induced pluripotent stem cells derived organoids with micro-and nano-technologies.</p> <p class="rtejustify"><strong>SINERGIA: </strong>Metabolic scaling, adapation and cooperation <em>in vitro</em>.</p> <p class="rtejustify"> </p> <h2 class="rtejustify"><strong>We want you!</strong></h2> <p class="rtejustify">Elenco<a href="http://www.centropiaggio.unipi.it/course/material/tesi-lm-disponibili-presso-il-gruppo-ivm"> tesi LM</a> e <a href="http://www.centropiaggio.unipi.it/course/material/tesi-triennali">Triennali</a> disponibili.</p> <p> </p> <h2 class="rtejustify"><strong>Spin Offs and Start-ups</strong></h2> <p class="rtejustify"><strong><a href="http://kirkstall.org">Kirkstall Ltd UK </a></strong>has licensed several patents from the group.</p> <p class="rtejustify"><strong><a href="http://www.ivtech.it">IVTech</a></strong> is a spin-off of University of Pisa dedicated to the commercialisation of in-vitro technologies to replace animal tests.</p> <p class="rtejustify"> </p> <h3><strong>Contact info:</strong></h3> <p><strong><a href="http://www.centropiaggio.unipi.it/~ahluwalia">Arti AHLUWALIA</a> <a href="https://www.centropiaggio.unipi.it/user/388/edit"> Chiara MAGLIARO </a></strong></p> <p>Phone +39 050 2217062 +39 050 2218271</p> <p>email: <a href="mailto:arti.ahluwalia@centropiaggio.unipi.itNOSPAM">arti.ahluwalia@unipi.it</a> <a href="mailto:chiara.magliaro@unipi.it">chiara.magliaro@unipi.it</a> </p> <p> </p> </div> </div></div></div> </div> </div> </div> <div class="col-md-4 col-lg-4"> <aside class="widget 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