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class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Followers</p><p class="data">40</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">5</p></div></a><a><div class="stat-container js-profile-coauthors" data-broccoli-component="user-info.coauthors-count" data-click-track="profile-expand-user-info-coauthors"><p class="label">Co-authors</p><p class="data">3</p></div></a><a href="/SawsanOran/mentions"><div class="stat-container"><p class="label">Mentions</p><p class="data">1</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="user-bio-container"><div class="profile-bio fake-truncate js-profile-about" style="margin: 0px;">I am a professor of Botany at the University of Jordan, Dept, of Biological Sciences<br /><div class="js-profile-less-about u-linkUnstyled u-tcGrayDarker u-textDecorationUnderline u-displayNone">less</div></div></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span><a class="ri-more-link js-profile-ri-list-card" data-click-track="profile-user-info-primary-research-interest" data-has-card-for-ri-list="10876832">View All (30)</a></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="10876832" href="https://www.academia.edu/Documents/in/Biological_Sciences"><div id="js-react-on-rails-context" style="display:none" 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id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Sawsan Oran</h3></div><div class="js-work-strip profile--work_container" data-work-id="115194392"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194392/In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia"><img alt="Research paper thumbnail of In vitro antiprotozoal activity of some medicinal plants methanolic extracts against Entamoeba histolytica and Giardia lamblia" class="work-thumbnail" src="https://attachments.academia-assets.com/111673358/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194392/In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia">In vitro antiprotozoal activity of some medicinal plants methanolic extracts against Entamoeba histolytica and Giardia lamblia</a></div><div class="wp-workCard_item"><span>Medicinal Plants - International Journal of Phytomedicines and Related Industries</span><span>, 2023</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c439174f05dbbf75463cb7405da62b4a" class="wp-workCard--action" rel="nofollow" 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Materials \u0026 methods: In vitro potency against Trypanosoma brucei brucei, T. b. rhodesiense, T. cruzi and Leishmania infantum beside cytotoxicity on MRC-5 fibroblasts were determined. Results \u0026 conclusion: Maytenus parviflora showed the highest activity against T. b. brucei (IC 50 of 0.6 μg/ml) and T. b. rhodesiense (IC 50 of 0.5 μg/ml) with low cytotoxicity (CC 50 of 30 μg/ml). Saussurea costus and Commiphora wightii, showed pronounced potency against T. cruzi with an IC 50 of 3.6 and 2.5 μg/ml, respectively. Jatropha pelargonifolia and Solanum villosum exhibited pronounced activity toward L. infantum with an IC 50 of 3.2 and 2.0 μg/ml, respectively. 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Malvaceae" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194373/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae">Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Dec 28, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional med...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194373"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194373"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194373; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194373]").text(description); $(".js-view-count[data-work-id=115194373]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194373; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194373']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194373, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194373]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194373,"title":"Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae","translated_title":"","metadata":{"abstract":"Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","publisher":"Diva Enterprises Private Limited","publication_date":{"day":28,"month":12,"year":2021,"errors":{}},"publication_name":"Research journal of pharmacy and technology"},"translated_abstract":"Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","internal_url":"https://www.academia.edu/115194373/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae","translated_internal_url":"","created_at":"2024-02-20T19:57:32.265-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":22050,"name":"Cytotoxicity","url":"https://www.academia.edu/Documents/in/Cytotoxicity"},{"id":103339,"name":"Antioxidant","url":"https://www.academia.edu/Documents/in/Antioxidant"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":1164053,"name":"PHARMACY TECHNOLOGY","url":"https://www.academia.edu/Documents/in/PHARMACY_TECHNOLOGY"},{"id":1335152,"name":"Viability assay","url":"https://www.academia.edu/Documents/in/Viability_assay"}],"urls":[{"id":39652416,"url":"https://doi.org/10.52711/0974-360x.2021.01115"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194372"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae"><img alt="Research paper thumbnail of Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae">Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Jan 25, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essent...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194372"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194372"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194372; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194372]").text(description); $(".js-view-count[data-work-id=115194372]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194372; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194372']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194372, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194372]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194372,"title":"Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae","translated_title":"","metadata":{"abstract":"Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","publisher":"Diva Enterprises Private Limited","publication_date":{"day":25,"month":1,"year":2022,"errors":{}},"publication_name":"Research journal of pharmacy and technology"},"translated_abstract":"Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","internal_url":"https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae","translated_internal_url":"","created_at":"2024-02-20T19:57:32.024-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":48465,"name":"Essential Oil","url":"https://www.academia.edu/Documents/in/Essential_Oil"},{"id":103339,"name":"Antioxidant","url":"https://www.academia.edu/Documents/in/Antioxidant"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":1164053,"name":"PHARMACY TECHNOLOGY","url":"https://www.academia.edu/Documents/in/PHARMACY_TECHNOLOGY"},{"id":1335152,"name":"Viability assay","url":"https://www.academia.edu/Documents/in/Viability_assay"}],"urls":[{"id":39652415,"url":"https://doi.org/10.52711/0974-360x.2022.00025"}]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194368"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194368/Plant_Biodiversity_of_the_Surrounding_Area_of_Wadi_Musa_Wastewater_Plant_"><img alt="Research paper thumbnail of Plant Biodiversity of the Surrounding Area of “Wadi Musa Wastewater Plant”" class="work-thumbnail" src="https://attachments.academia-assets.com/111673344/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194368/Plant_Biodiversity_of_the_Surrounding_Area_of_Wadi_Musa_Wastewater_Plant_">Plant Biodiversity of the Surrounding Area of “Wadi Musa Wastewater Plant”</a></div><div class="wp-workCard_item"><span>Dirasat: Pure Sciences</span><span>, Sep 8, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ce1ac6240c83a13d3ceb2b807784da76" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673344,"asset_id":115194368,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673344/download_file?st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194368"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194368"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194368; 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The composition of the flowering wild plants has been studied, field trips have been conducted to the area and collections of any available plant materials with emphasis on vascular flowering plants have been made. The results revealed a high botanical diversity of the area in terms of the number of plant species recorded. A total number of 71 species has been recorded belongs to 69 genera and 38 families. This number of plant species represents 35% of the total flora of the entire Petra area/Wadi Musa. Moreover, some recorded species are considered as endemic to the area such as the elegant Iris of Petra (Iris petrana) or the medicinal rare Globularia arabica, Galium petrae and Verbascum petrae. A number of historical economic trees have been found in the study area like the old Quercus coccifera, Pistacia atlantica, Amygdalus korschinskyii, Ficus sycomorus and Juniperus phoenica. Other recorded species are both palatable and medicinal like Achillea fragrantissima, Artemisia herba-alba, Peganum harmala, Paronychia argentea and many others. However, the majority of plant species recorded in the study area are facing the danger of loss and degradation, as the area is severely exposed to either man impact or environmental damaging factors. Some of these are the overgrazing, cutting of trees and collection of herbs and other irrational activities of the Bedwin populations of that area, as well as the touristic activities hence the area is rich with many archaeological sites.","publication_date":{"day":8,"month":9,"year":2010,"errors":{}},"publication_name":"Dirasat: Pure Sciences","grobid_abstract_attachment_id":111673344},"translated_abstract":null,"internal_url":"https://www.academia.edu/115194368/Plant_Biodiversity_of_the_Surrounding_Area_of_Wadi_Musa_Wastewater_Plant_","translated_internal_url":"","created_at":"2024-02-20T19:57:31.142-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":111673344,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673344/thumbnails/1.jpg","file_name":"4990.pdf","download_url":"https://www.academia.edu/attachments/111673344/download_file?st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Plant_Biodiversity_of_the_Surrounding_Ar.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673344/4990.pdf?1708487911=\u0026response-content-disposition=attachment%3B+filename%3DPlant_Biodiversity_of_the_Surrounding_Ar.pdf\u0026Expires=1733349596\u0026Signature=KS9O3AdoufXocT7XaQJy50b-DeXsvVbvWeplPbTDaECHnrPWH0aS~81e2sgb232COtycZ7Z31YxribMDWQpNL2oqx8VwT~30A8x3OGpiIPAZWUzdr5A-iJ-fdvUSHKjOyKjF7-JnsrBFviLeFkZW-gBSyd-T~hKfmeiWTd7aPw3bsts5kr-IxK-5O8Hpab4IEUVa-LZQpRt4OxocEgIAZzUq-7BCSkBhPI3RLEKzVGZZjXpfFftMbTYTWU1lXREkx3AkzBVD4b5tOgevLWdKFBNsm~hlJMnCGFL286Fdv6kq79SyKbJTv3MFjsleVlIO4NFvgdkRabcFH2HNpd-YHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Plant_Biodiversity_of_the_Surrounding_Area_of_Wadi_Musa_Wastewater_Plant_","translated_slug":"","page_count":21,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":111673344,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673344/thumbnails/1.jpg","file_name":"4990.pdf","download_url":"https://www.academia.edu/attachments/111673344/download_file?st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Plant_Biodiversity_of_the_Surrounding_Ar.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673344/4990.pdf?1708487911=\u0026response-content-disposition=attachment%3B+filename%3DPlant_Biodiversity_of_the_Surrounding_Ar.pdf\u0026Expires=1733349596\u0026Signature=KS9O3AdoufXocT7XaQJy50b-DeXsvVbvWeplPbTDaECHnrPWH0aS~81e2sgb232COtycZ7Z31YxribMDWQpNL2oqx8VwT~30A8x3OGpiIPAZWUzdr5A-iJ-fdvUSHKjOyKjF7-JnsrBFviLeFkZW-gBSyd-T~hKfmeiWTd7aPw3bsts5kr-IxK-5O8Hpab4IEUVa-LZQpRt4OxocEgIAZzUq-7BCSkBhPI3RLEKzVGZZjXpfFftMbTYTWU1lXREkx3AkzBVD4b5tOgevLWdKFBNsm~hlJMnCGFL286Fdv6kq79SyKbJTv3MFjsleVlIO4NFvgdkRabcFH2HNpd-YHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":261,"name":"Geography","url":"https://www.academia.edu/Documents/in/Geography"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":17825,"name":"Biodiversity","url":"https://www.academia.edu/Documents/in/Biodiversity"}],"urls":[{"id":39652412,"url":"https://journals.ju.edu.jo/dirasatsci/article/download/1640/1628"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194367"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194367/Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review"><img alt="Research paper thumbnail of Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194367/Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review">Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Jan 25, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientifi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientific literature. The challenge of disease and death caused by infectious diseases like viruses and bacteria, and as infectious diseases evolve and pathogens develop resistance to existing pharmaceuticals, the search for new novel leads, possibly with different modes of action, against bacterial and viral diseases has intensified in recent years. The intent of this review is to provide prevalent information on the antibacterial and antiviral potential in medicinal plants in Jordan, mode of action, type of viruses and bacteria, and phytochemical contents. It has been demonstrated by several studies presented in this review that medicinal plants in Jordan are rich in phytochemicals and possess antiviral and antibacterial properties.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194367"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194367"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194367; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194367]").text(description); $(".js-view-count[data-work-id=115194367]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194367; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194367']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194367, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194367]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194367,"title":"Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review","translated_title":"","metadata":{"abstract":"The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientific literature. The challenge of disease and death caused by infectious diseases like viruses and bacteria, and as infectious diseases evolve and pathogens develop resistance to existing pharmaceuticals, the search for new novel leads, possibly with different modes of action, against bacterial and viral diseases has intensified in recent years. The intent of this review is to provide prevalent information on the antibacterial and antiviral potential in medicinal plants in Jordan, mode of action, type of viruses and bacteria, and phytochemical contents. It has been demonstrated by several studies presented in this review that medicinal plants in Jordan are rich in phytochemicals and possess antiviral and antibacterial properties.","publisher":"Diva Enterprises Private Limited","publication_date":{"day":25,"month":1,"year":2022,"errors":{}},"publication_name":"Research journal of pharmacy and technology"},"translated_abstract":"The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientific literature. The challenge of disease and death caused by infectious diseases like viruses and bacteria, and as infectious diseases evolve and pathogens develop resistance to existing pharmaceuticals, the search for new novel leads, possibly with different modes of action, against bacterial and viral diseases has intensified in recent years. The intent of this review is to provide prevalent information on the antibacterial and antiviral potential in medicinal plants in Jordan, mode of action, type of viruses and bacteria, and phytochemical contents. It has been demonstrated by several studies presented in this review that medicinal plants in Jordan are rich in phytochemicals and possess antiviral and antibacterial properties.","internal_url":"https://www.academia.edu/115194367/Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review","translated_internal_url":"","created_at":"2024-02-20T19:57:30.908-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":110666,"name":"Phytochemical","url":"https://www.academia.edu/Documents/in/Phytochemical"},{"id":1164053,"name":"PHARMACY TECHNOLOGY","url":"https://www.academia.edu/Documents/in/PHARMACY_TECHNOLOGY"}],"urls":[{"id":39652411,"url":"https://doi.org/10.52711/0974-360x.2022.00021"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194366"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/115194366/Antimicrobial_activity_of_Globularia_arabica_Jaub_and_Spach_and_G_alypum_L_Globulariaceae_"><img alt="Research paper thumbnail of Antimicrobial activity of Globularia arabica Jaub. and Spach and G. alypum L. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194365"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/115194365/Evaluation_of_the_antioxidant_activities_of_green_synthesized_selenium_nanoparticles_and_their_conjugated_polyethylene_glycol_PEG_form_in_vivo"><img alt="Research paper thumbnail of Evaluation of the antioxidant activities of green synthesized selenium nanoparticles and their conjugated polyethylene glycol (PEG) form in vivo" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/115194365/Evaluation_of_the_antioxidant_activities_of_green_synthesized_selenium_nanoparticles_and_their_conjugated_polyethylene_glycol_PEG_form_in_vivo">Evaluation of the antioxidant activities of green synthesized selenium nanoparticles and their conjugated polyethylene glycol (PEG) form in vivo</a></div><div class="wp-workCard_item"><span>OpenNano</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194365"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194365"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194365; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194364"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194364/Induction_of_apoptosis_by_Ruta_chalepensis_L_essential_oil_in_human_breast_cancer_cells_MCF_7_"><img alt="Research paper thumbnail of Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)" class="work-thumbnail" src="https://attachments.academia-assets.com/111673355/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194364/Induction_of_apoptosis_by_Ruta_chalepensis_L_essential_oil_in_human_breast_cancer_cells_MCF_7_">Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Pharmacognosy Research</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Context: Recent scientific studies have reported that essential oils induce apoptosis in various ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (EO) of Ruta chalepensis L. against MCF-7 cell line. Methods: Cytotoxicity was determined using methyl thiazol tetrazolium assay. The apoptotic activity of EO was analyzed using annexin V-fluorescein isothiocyanate/propidium iodide binding flow cytometry. The cell morphology was inspected under an inverted microscope. DAPI staining assay was used for the morphological observation. Activation of caspases-3/7, -8, and-9 was assessed using a caspase assay kit. Results: Ruta chalepensis essential oil significantly inhibited the proliferation of MCF-7 cells at 72 h. Moreover, the results showed that cell death is associated with the apoptotic process, and the number of apoptotic cells was significantly increased in the groups treated with EO than ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="65950bbdd7daca388323e9e9eb347d4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673355,"asset_id":115194364,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673355/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194364"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194364"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194364; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194364]").text(description); $(".js-view-count[data-work-id=115194364]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194364; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194364']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194364, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "65950bbdd7daca388323e9e9eb347d4c" } } $('.js-work-strip[data-work-id=115194364]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194364,"title":"Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)","translated_title":"","metadata":{"abstract":"Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. 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Moreover, the results showed that cell death is associated with the apoptotic process, and the number of apoptotic cells was significantly increased in the groups treated with EO than ...","publisher":"Garval Editorial Ltda.","publication_name":"Journal of Pharmacy \u0026amp; Pharmacognosy Research"},"translated_abstract":"Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (EO) of Ruta chalepensis L. against MCF-7 cell line. Methods: Cytotoxicity was determined using methyl thiazol tetrazolium assay. The apoptotic activity of EO was analyzed using annexin V-fluorescein isothiocyanate/propidium iodide binding flow cytometry. The cell morphology was inspected under an inverted microscope. DAPI staining assay was used for the morphological observation. 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href="https://www.academia.edu/115194363/Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_"><img alt="Research paper thumbnail of Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)" class="work-thumbnail" src="https://attachments.academia-assets.com/111673352/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194363/Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_">Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Pharmacognosy Research</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jord...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jordan and neighboring countries. Aims: To evaluate the cytotoxic potential of ethanolic and aqueous extracts from the aerial parts of A. orientalis against three cell lines MCF-7, Caco-2, and HDFa. In addition to assessing the total phenolic and flavonoid contents, antioxidant activity. Further to analyze the phytochemical constituents. Methods: The phytochemical analysis was performed using gas chromatography/mass spectrometry. The total phenolic (TPC) and flavonoid (TFC) contents were assessed using colorimetric methods. The antioxidant properties of both extracts were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power ability. Cytotoxicity was investigated using methyl thiazol tetrazolium (MTT) assay. Results: The most abundant compounds in the extract were 9-octadecenoic acid, methyl ester, (E)- (27.2%), hexadecanoic acid, methyl ester (12...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="600add623fd3a68a4cd91cc1007faa87" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673352,"asset_id":115194363,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673352/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194363"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194363"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194363; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194363]").text(description); $(".js-view-count[data-work-id=115194363]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194363; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194363']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194363, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "600add623fd3a68a4cd91cc1007faa87" } } $('.js-work-strip[data-work-id=115194363]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194363,"title":"Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. 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The antioxidant properties of both extracts were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power ability. Cytotoxicity was investigated using methyl thiazol tetrazolium (MTT) assay. 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/115194362/Cinchona_officinalis_Cinchona_Tree_and_Corylus_avellana_Common_Hazel_">Cinchona officinalis (Cinchona Tree) and Corylus avellana (Common Hazel)</a></div><div class="wp-workCard_item"><span>CRC Press eBooks</span><span>, May 9, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194362"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span 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el: this, workJSON: {"id":115194362,"title":"Cinchona officinalis (Cinchona Tree) and Corylus avellana (Common Hazel)","translated_title":"","metadata":{"publisher":"Informa","publication_date":{"day":9,"month":5,"year":2022,"errors":{}},"publication_name":"CRC Press 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Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants"},{"id":878506,"name":"Quinine","url":"https://www.academia.edu/Documents/in/Quinine"},{"id":3489148,"name":"Quinidine","url":"https://www.academia.edu/Documents/in/Quinidine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194361"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats"><img alt="Research paper thumbnail of Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats">Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats</a></div><div class="wp-workCard_item"><span>Heliyon</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P &amp;lt; 0.05) and increased the fibroblast&amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194361"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194361"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194361; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194361]").text(description); $(".js-view-count[data-work-id=115194361]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194361; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194361']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194361, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194361]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194361,"title":"Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats","translated_title":"","metadata":{"abstract":"Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P \u0026amp;lt; 0.05) and increased the fibroblast\u0026amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.","publisher":"Elsevier BV","publication_name":"Heliyon"},"translated_abstract":"Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P \u0026amp;lt; 0.05) and increased the fibroblast\u0026amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.","internal_url":"https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats","translated_internal_url":"","created_at":"2024-02-20T19:57:29.715-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus"},{"id":350937,"name":"Fibroblast","url":"https://www.academia.edu/Documents/in/Fibroblast"}],"urls":[{"id":39652408,"url":"https://api.elsevier.com/content/article/PII:S2405844022013597?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194360"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/115194360/Effects_of_the_Oral_Administration_of_Methanolic_Extracts_of_Some_Jordanian_Medicinal_Plants_on_Wound_Healing_in_Diabetic_Rats"><img alt="Research paper thumbnail of Effects of the Oral Administration of Methanolic Extracts of Some Jordanian Medicinal Plants on Wound Healing in Diabetic Rats" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/115194360/Effects_of_the_Oral_Administration_of_Methanolic_Extracts_of_Some_Jordanian_Medicinal_Plants_on_Wound_Healing_in_Diabetic_Rats">Effects of the Oral Administration of Methanolic Extracts of Some Jordanian Medicinal Plants on Wound Healing in Diabetic Rats</a></div><div class="wp-workCard_item"><span>SSRN Electronic Journal</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194360"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194360"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194360; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194359"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats"><img alt="Research paper thumbnail of Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats">Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats</a></div><div class="wp-workCard_item"><span>Journal of Cosmetic Dermatology</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">AimThis study assessed the effects of topical application of R. coriaria extract on the rate of w...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194359"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194359"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194359; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194359]").text(description); $(".js-view-count[data-work-id=115194359]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194359; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194359']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194359, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194359]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194359,"title":"Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats","translated_title":"","metadata":{"abstract":"AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Journal of Cosmetic Dermatology"},"translated_abstract":"AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...","internal_url":"https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats","translated_internal_url":"","created_at":"2024-02-20T19:57:29.314-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":88216,"name":"Cosmetic Dermatology","url":"https://www.academia.edu/Documents/in/Cosmetic_Dermatology"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":802828,"name":"Hydroxyproline","url":"https://www.academia.edu/Documents/in/Hydroxyproline"}],"urls":[{"id":39652407,"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jocd.14668"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194358"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194358/Assessment_of_the_antibacterial_effects_of_Moringa_peregrina_extracts"><img alt="Research paper thumbnail of Assessment of the antibacterial effects of Moringa peregrina extracts" class="work-thumbnail" src="https://attachments.academia-assets.com/111673336/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194358/Assessment_of_the_antibacterial_effects_of_Moringa_peregrina_extracts">Assessment of the antibacterial effects of Moringa peregrina extracts</a></div><div class="wp-workCard_item"><span>African Journal of Microbiology Research</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="948a908740abd6ceafc2cd9c8931dd00" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673336,"asset_id":115194358,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673336/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194358"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194358"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194358; 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The effect of plant extracts were tested against three bacterial species: Escherichia coli (E. coli ATCC25922), Staphylococcus aureus (S. aureus ATCC 43300) and Klebsiella pneumoniae (K. pneumoniae ATCC 13883). M. peregrina ethanolic extracts showed significant antibacterial effect on the three tested bacterial strains using the disc diffusion method. The inhibition zones caused by leaf ethanolic extracts were 14 to 30, 8 to 19 and 9 to 22 mm in diameter against E. coli, K. pneumonia, and S. aureus, respectively. Root ethanolic extracts showed inhibition zones as 18 to 42, 44 to 59 and 34 to 45 mm in diameter against E. coli, K. pneumonia, and S. aureus, respectively. Seed extract caused inhibitory zones of 16 to 38, 6 to 32 and 6 to 18 mm in diameter against E. coli, K. pneumonia and S. aureus, respectively. The results showed that the zones of inhibition for the three bacterial species increased in a dose dependant manner and that the M.peregrina root ethanolic extract exhibited more potent inhibition. The other test done to assess the antibacterial effect of M. peregrina ethanolic extracts was the minimum inhibitory concentrations (MIC). Such test was conducted on the same three bacterial species, where the MIC for the M. peregrina leaf extract for E. coli, K. pneumoniae, and S. aureus were 12.0, 15.0 and 18 mg/ml, respectively. The MIC for seed ethanolic extract was 13.0 and 7.0 mg/ml against E. coli, K. pneumoniae and S. aureus respectively. Also, the MIC for root ethanolic extract of M. peregrine against E. coli, K. pneumoniae and S. aureus was 9.0, 3, 2, and 5 mg/ml, respectively. 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194357/Micropropagation_of_the_Wild_Endangered_Daffodil_Narcissus_Tazetta_L">Micropropagation of the Wild Endangered Daffodil Narcissus Tazetta L</a></div><div class="wp-workCard_item"><span>Acta Horticulturae</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="da81e53eeeb43b52ab1e4eccf6edb2b1" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673346,"asset_id":115194357,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673346/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner 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It is an endangered and medicinal plant grown in Jordan and neighboring countries. A protocol has been developed for efficient rapid micropropagation of Narcissus tazetta through adventitious shoot induction. One type of explant has been used which is multi bulb scale explants. Field-derived material was successfully sterilised using 70% ethanol for 3 mins. and 1% NaOCl for 20 mins followed by hot water treatment for 1 hour at 54 o C before dissecting out bulb scales. The results showed that high adventitious shoot formation was obtained by supplementing the culture medium with high ratio concentration of BAP to low NAA concentration, which are (0.0, 44.4 µM) for T4 and (2.7, 44.4µM) for T7. On the other hand best rooting results were obtained when supplementing the culture medium with NAA alone.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Acta Horticulturae","grobid_abstract_attachment_id":111673346},"translated_abstract":null,"internal_url":"https://www.academia.edu/115194357/Micropropagation_of_the_Wild_Endangered_Daffodil_Narcissus_Tazetta_L","translated_internal_url":"","created_at":"2024-02-20T19:57:27.778-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":111673346,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673346/thumbnails/1.jpg","file_name":"ActaHortic.2009.826.1820240221-1-aibd0h.pdf","download_url":"https://www.academia.edu/attachments/111673346/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Micropropagation_of_the_Wild_Endangered.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673346/ActaHortic.2009.826.1820240221-1-aibd0h-libre.pdf?1708488635=\u0026response-content-disposition=attachment%3B+filename%3DMicropropagation_of_the_Wild_Endangered.pdf\u0026Expires=1733349597\u0026Signature=H0yYIaMFDie6eP4dVbW-aYG4JyG5gK8rpZLN2Odtu3cuASB4Pl1hPBJZOsV1eM-MGsBwURw1fqlOHocunWdStOOmTCF7V7Og2gF04TMevWT-zwNkMQX2VCX9xn8LvrWhNBuG65BWQXPUSShfgeYbThcPbdK6aZbbcsgvDfMK9ZBwhDBJbYH43-QUGdff0T8frvHmjCBD0yjP6rtxGzIxvbUmuFOMvcnRTYBh-rkkQsLyQNSSmU7XR9~hcPVl9NYyxITb07qZ63D7RRwW6wLFLTHfFoTuH23SqTWguaeedYOUbHK5RCAVkKt76kK5uTWGPT7q5yYpUHJW6p-WT542ug__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Micropropagation_of_the_Wild_Endangered_Daffodil_Narcissus_Tazetta_L","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":111673346,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673346/thumbnails/1.jpg","file_name":"ActaHortic.2009.826.1820240221-1-aibd0h.pdf","download_url":"https://www.academia.edu/attachments/111673346/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Micropropagation_of_the_Wild_Endangered.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673346/ActaHortic.2009.826.1820240221-1-aibd0h-libre.pdf?1708488635=\u0026response-content-disposition=attachment%3B+filename%3DMicropropagation_of_the_Wild_Endangered.pdf\u0026Expires=1733349597\u0026Signature=H0yYIaMFDie6eP4dVbW-aYG4JyG5gK8rpZLN2Odtu3cuASB4Pl1hPBJZOsV1eM-MGsBwURw1fqlOHocunWdStOOmTCF7V7Og2gF04TMevWT-zwNkMQX2VCX9xn8LvrWhNBuG65BWQXPUSShfgeYbThcPbdK6aZbbcsgvDfMK9ZBwhDBJbYH43-QUGdff0T8frvHmjCBD0yjP6rtxGzIxvbUmuFOMvcnRTYBh-rkkQsLyQNSSmU7XR9~hcPVl9NYyxITb07qZ63D7RRwW6wLFLTHfFoTuH23SqTWguaeedYOUbHK5RCAVkKt76kK5uTWGPT7q5yYpUHJW6p-WT542ug__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":18433,"name":"Micropropagation","url":"https://www.academia.edu/Documents/in/Micropropagation"},{"id":23979,"name":"Endangered Species","url":"https://www.academia.edu/Documents/in/Endangered_Species"},{"id":75317,"name":"Narcissus","url":"https://www.academia.edu/Documents/in/Narcissus"},{"id":2674671,"name":"Horticultural production","url":"https://www.academia.edu/Documents/in/Horticultural_production"}],"urls":[{"id":39652405,"url":"http://www.actahort.org/members/showpdf?booknrarnr=826_18"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194298"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194298/Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud"><img alt="Research paper thumbnail of Ruta Graveolens, Peganum Harmala and Citrullus Colocynthis Methanolic Extracts Have in Vitro Protoscolocidal Effects and Act Against Bacteria Isolated From Echinococcal Hydatid Cyst Fliud" class="work-thumbnail" src="https://attachments.academia-assets.com/111673322/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194298/Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud">Ruta Graveolens, Peganum Harmala and Citrullus Colocynthis Methanolic Extracts Have in Vitro Protoscolocidal Effects and Act Against Bacteria Isolated From Echinococcal Hydatid Cyst Fliud</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Echinococcosis is a common and endemic disease that affects both humans and animals. In this stud...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. 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In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. The most effective...","publisher":"Research Square Platform LLC","publication_date":{"day":null,"month":null,"year":2022,"errors":{}}},"translated_abstract":"Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. The most effective...","internal_url":"https://www.academia.edu/115194298/Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud","translated_internal_url":"","created_at":"2024-02-20T19:56:04.863-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":111673322,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673322/thumbnails/1.jpg","file_name":"latest.pdf","download_url":"https://www.academia.edu/attachments/111673322/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ruta_Graveolens_Peganum_Harmala_and_Citr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673322/latest-libre.pdf?1708488666=\u0026response-content-disposition=attachment%3B+filename%3DRuta_Graveolens_Peganum_Harmala_and_Citr.pdf\u0026Expires=1733349597\u0026Signature=OO5oSenXUmzP8T2bAAotuQaNRo5TP9C7V-0B5aCOioz96O2~co0JgiUbfsUZXOE2eAOw-0bgTY5jpCMK~aWtcz8i5yD0-mc9T5e3Ni-hzq6ixbIeFfQiMbQXVt8kfbdBxNziCkf7jh9ccOPOq60a1C-vXmxXaWvfzLuRxdsqayZRh~fD64AmnK5bz7B1dj-676weM~meb9PXl0mjIE8AGPBRsq5l5hQquFvuhqrVT-BMam33LACKWDm-Z51xAu16wp4BtqynpwctjuJj~xn-7dUDaQMENjSl-us7AiOdgI4HzoLrKbCJbR2iEjzjMrYzu8PM0aTFnhBc91mmDYrBUA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud","translated_slug":"","page_count":18,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":111673322,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673322/thumbnails/1.jpg","file_name":"latest.pdf","download_url":"https://www.academia.edu/attachments/111673322/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ruta_Graveolens_Peganum_Harmala_and_Citr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673322/latest-libre.pdf?1708488666=\u0026response-content-disposition=attachment%3B+filename%3DRuta_Graveolens_Peganum_Harmala_and_Citr.pdf\u0026Expires=1733349597\u0026Signature=OO5oSenXUmzP8T2bAAotuQaNRo5TP9C7V-0B5aCOioz96O2~co0JgiUbfsUZXOE2eAOw-0bgTY5jpCMK~aWtcz8i5yD0-mc9T5e3Ni-hzq6ixbIeFfQiMbQXVt8kfbdBxNziCkf7jh9ccOPOq60a1C-vXmxXaWvfzLuRxdsqayZRh~fD64AmnK5bz7B1dj-676weM~meb9PXl0mjIE8AGPBRsq5l5hQquFvuhqrVT-BMam33LACKWDm-Z51xAu16wp4BtqynpwctjuJj~xn-7dUDaQMENjSl-us7AiOdgI4HzoLrKbCJbR2iEjzjMrYzu8PM0aTFnhBc91mmDYrBUA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":113903,"name":"Bacteria","url":"https://www.academia.edu/Documents/in/Bacteria"},{"id":181597,"name":"Root-Mean Square Error","url":"https://www.academia.edu/Documents/in/Root-Mean_Square_Error"},{"id":894289,"name":"Citrullus Colocynthis","url":"https://www.academia.edu/Documents/in/Citrullus_Colocynthis"},{"id":1487885,"name":"Peganum harmala L.","url":"https://www.academia.edu/Documents/in/Peganum_harmala_L"},{"id":2458506,"name":"Ruta graveolens","url":"https://www.academia.edu/Documents/in/Ruta_graveolens"},{"id":3539924,"name":"Peganum harmala L","url":"https://www.academia.edu/Documents/in/Peganum_harmala_L-1"}],"urls":[{"id":39652357,"url":"https://www.researchsquare.com/article/rs-1388080/v1"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111349553"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan"><img alt="Research paper thumbnail of Flora of Bader Al-Jadida County, western high mountains of Amman city/Jordan" class="work-thumbnail" src="https://attachments.academia-assets.com/108914893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan">Flora of Bader Al-Jadida County, western high mountains of Amman city/Jordan</a></div><div class="wp-workCard_item"><span>International Journal of Herbal Medicine</span><span>, Oct 1, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="84bd70df476a52df040a5f6d895b0bca" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108914893,"asset_id":111349553,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111349553"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111349553"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111349553; 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The flowering plant specimen have been collected from the area and identified. A number of 259 species and 2 subspecies belong to 179 genera and 44 families are recorded. Photographs of some selected common plant species in the study area as well as photographs for some natural views are demonstrated, with emphasis on the topography of the heights that are dominated by forest stands of typically Mediterranean vegetation elements of mixed evergreen and deciduous oak trees of Quercus coccifera and Q. ithaburensis, Amygdalus communis, Crataegus aronia and Pyrus syriaca, shrubs and cultivated tress like, grape vines, Olive trees, fig trees (Ficus indica), pomegranate trees (Punica granatum) and mulberries trees (Morus alba and M. nigra). The study area is blessed by lots of aromatic plant species like Lonicera etrusca, Calicotome villosa, Thymus capitatus, Varthemia iphionoides, Narcissus tazetta and others, orchid species, Mentha aquatica and others. Lots of medicinal plants are also recorded in the study area, that are still used in folk medicine by the local people like Varthemia iphionoides, Arum palaestinum, Vinca herbacea, Dittrichia viscosa,, Achillea santolina, Bongardia chrysogonum, Thymus capitatus and others. Many recorded species are edible plants like Cyclamen persicum, the shrubby raspberry Rubus sanguineous, Capparis spinosa, Pyrus syriaca, Crataegus aronia, Gundelia tournefortii, Rhus coriaria, Thymus capitatus, Malva sylvestris and some others. A number of showy, rare and endangered aromatic plant species are recorded like Orchis antolica, Narcissus tazetta, Sternbergia clusiana, Tulipa agenesis, Styrax officinalis and Lonicera etrusca. Few stands of Pistacia atlantica and P. palaestina trees are also recorded.","publication_date":{"day":1,"month":10,"year":2015,"errors":{}},"publication_name":"International Journal of Herbal Medicine","grobid_abstract_attachment_id":108914893},"translated_abstract":null,"internal_url":"https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan","translated_internal_url":"","created_at":"2023-12-13T11:12:01.536-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108914893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914893/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914893/3-2-4.1-libre.pdf?1702495232=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=aHhcfLMwm9xaGjVr6~7vs7GK-bQVFkAkpUNjmkkoduNBGyFvjlx8iCn5q2KiBq0LHz9U414MxA3SqCa9VttcdJZ2VJAaGYZjpoIHyoJ5enMuqDvIef8DiXS0YApJeWE5TGQmdUIz3QbAY6qMFqUaID5LCPukGOh1nDU9VDMIy8YN22tXl8lK6XCXk9ULfGVTqEjO~Rf9vnfP7Ani0I7LWQ05vE8IvGvEqwcxVm2KoXEg84hw7UWCrrduQxTp1h2P6r~bJLVg5TIlIrIXpLRtZPxH~llH2~ambBMzFzJvUnK8uoIGJ1fDDLVpWAV5H92odj3rAm4L6yFCGs058LwiWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":108914893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914893/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914893/3-2-4.1-libre.pdf?1702495232=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=aHhcfLMwm9xaGjVr6~7vs7GK-bQVFkAkpUNjmkkoduNBGyFvjlx8iCn5q2KiBq0LHz9U414MxA3SqCa9VttcdJZ2VJAaGYZjpoIHyoJ5enMuqDvIef8DiXS0YApJeWE5TGQmdUIz3QbAY6qMFqUaID5LCPukGOh1nDU9VDMIy8YN22tXl8lK6XCXk9ULfGVTqEjO~Rf9vnfP7Ani0I7LWQ05vE8IvGvEqwcxVm2KoXEg84hw7UWCrrduQxTp1h2P6r~bJLVg5TIlIrIXpLRtZPxH~llH2~ambBMzFzJvUnK8uoIGJ1fDDLVpWAV5H92odj3rAm4L6yFCGs058LwiWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":108914894,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914894/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914894/download_file","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914894/3-2-4.1-libre.pdf?1702495239=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=cOQP-KJVoZTAWx7BKYCFdu9g~ut4mCIYmWx1a31yRbW2bH9ttzwAi8KbKz2xRWbEQTKcXPzkyilaJ1R3HabjrP618~pGfhx19NzhXqqM4OrxStcNH87vQ1PjFmwYUxZcGsLA40qkoAqUALNVal3YJTeGM5Al~7Klt1jH52JlTbgW1JWOeBAvnh90i0ojgUMtj2KcfBA1NqJWHEtyi0~vsWt75P5fNI~OaaZ6DLzCsn4jf2Y4pAq0QfvpefpNPPW1EC8bmkr9JDHTdzs98bg80Tihft3VNYksT05I6iP0gD4G8XPd4q-foWj4NqkrYdZ54hBWgz1E6IoLkuW4Yypy2Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":261,"name":"Geography","url":"https://www.academia.edu/Documents/in/Geography"},{"id":44297,"name":"Herbal Medicine","url":"https://www.academia.edu/Documents/in/Herbal_Medicine"}],"urls":[{"id":37034238,"url":"https://www.florajournal.com/archives/2015/vol3issue4/PartA/3-2-4.1.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111349552"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines"><img alt="Research paper thumbnail of Evaluation of the antiproliferative effect of selected plant extracts on colon and skin cancer cell lines" class="work-thumbnail" src="https://attachments.academia-assets.com/108914939/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines">Evaluation of the antiproliferative effect of selected plant extracts on colon and skin cancer cell lines</a></div><div class="wp-workCard_item"><span>journal of applied pharmaceutical science</span><span>, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="45bd73af67e736becb26ae9d3aab94bb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108914939,"asset_id":111349552,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111349552"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111349552"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111349552; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111349552]").text(description); $(".js-view-count[data-work-id=111349552]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111349552; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111349552']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111349552, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "45bd73af67e736becb26ae9d3aab94bb" } } $('.js-work-strip[data-work-id=111349552]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111349552,"title":"Evaluation of the antiproliferative effect of selected plant extracts on colon and skin cancer cell lines","translated_title":"","metadata":{"publisher":"Open Science Publishers LLP","grobid_abstract":"The aim of this study was to assess the antiproliferative effect of extracts obtained from medicinal plants that grow wild in Jordan against the human melanoma (WM136-1A) and colon cancer (Caco-2 cancer) cell lines using fibroblast cell lines as control cells. The selected plants are Varthemia iphionoides (Asteraceae), Micromeria myrtifolia (Lamiaceae), Micromeria nervosa (Lamiaceae), Origanum dayi (Lamiaceae), Ajuga chia (Lamiaceae), Salvia palaestina (Lamiaceae), and Bongardia chrysogonum (Berberidaceae). The results showed that M. nervosa and O. dayi exhibited antiproliferative activity against Caco-2 cancer cell line, with half-maximal inhibitory concentrations (IC 50) that equal 98 ± 2.5 and 73.6 ± 3.4 μg/ml, respectively. Furthermore, A. chia, B. chrysogonum, and O. dayi exhibited antiproliferative activity against the WM136-1A cancer cell line, with IC 50 that equals 400 ± 5.1, 98.1 ± 3.2, and 245 ± 3.6 μg/ml, respectively. None of the extracts had an effect on fibroblast cells at any used concentration. In conclusion, the extracts of M. nervosa, O. dayi, A. chia, and B. chrysogonum showed promising antiproliferative potential and can be good candidates for the development of novel anticancerous agents.","publication_date":{"day":null,"month":null,"year":2022,"errors":{}},"publication_name":"journal of applied pharmaceutical science","grobid_abstract_attachment_id":108914939},"translated_abstract":null,"internal_url":"https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines","translated_internal_url":"","created_at":"2023-12-13T11:12:01.343-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108914939,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914939/thumbnails/1.jpg","file_name":"3759_pdf.pdf","download_url":"https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Evaluation_of_the_antiproliferative_effe.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914939/3759_pdf-libre.pdf?1702495241=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_of_the_antiproliferative_effe.pdf\u0026Expires=1733349597\u0026Signature=EAXGNZS~3F6PuCu0v2EJZo5COgpdlPAZGz3ZEge5gTTDOXrf4eGbJ6R53bN-l-jlDT2k-WujKKqVdWy6AI0VIZDIWcD20s3y7tA7yZkIbFXPl75b8FqZgGRPVDhSEPRvCVGXhguSnriz47G5Qx3JplW8y-dZL3nTHfVY1NZv3cMP91pYd0H3i-ZK2CxPbQjuPqVUiO-S6Lt2ahS3CxF0DgqZllVrfKpnJHhPyNVpitZvbModiYpy82efELriwfyRfsh~NsQAdLbRGejraQbUyarW~NfV9uA1liiUbGcvbJ5sht2XjJ2RT5ZKf04IOnjjTbS9iISIn7~W397P7M4isg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":108914939,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914939/thumbnails/1.jpg","file_name":"3759_pdf.pdf","download_url":"https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Evaluation_of_the_antiproliferative_effe.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914939/3759_pdf-libre.pdf?1702495241=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_of_the_antiproliferative_effe.pdf\u0026Expires=1733349597\u0026Signature=EAXGNZS~3F6PuCu0v2EJZo5COgpdlPAZGz3ZEge5gTTDOXrf4eGbJ6R53bN-l-jlDT2k-WujKKqVdWy6AI0VIZDIWcD20s3y7tA7yZkIbFXPl75b8FqZgGRPVDhSEPRvCVGXhguSnriz47G5Qx3JplW8y-dZL3nTHfVY1NZv3cMP91pYd0H3i-ZK2CxPbQjuPqVUiO-S6Lt2ahS3CxF0DgqZllVrfKpnJHhPyNVpitZvbModiYpy82efELriwfyRfsh~NsQAdLbRGejraQbUyarW~NfV9uA1liiUbGcvbJ5sht2XjJ2RT5ZKf04IOnjjTbS9iISIn7~W397P7M4isg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":37292,"name":"Colorectal cancer","url":"https://www.academia.edu/Documents/in/Colorectal_cancer"}],"urls":[{"id":37034237,"url":"https://doi.org/10.7324/japs.2022.121110"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="1324869" id="papers"><div class="js-work-strip profile--work_container" data-work-id="115194392"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194392/In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia"><img alt="Research paper thumbnail of In vitro antiprotozoal activity of some medicinal plants methanolic extracts against Entamoeba histolytica and Giardia lamblia" class="work-thumbnail" src="https://attachments.academia-assets.com/111673358/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194392/In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia">In vitro antiprotozoal activity of some medicinal plants methanolic extracts against Entamoeba histolytica and Giardia lamblia</a></div><div class="wp-workCard_item"><span>Medicinal Plants - International Journal of Phytomedicines and Related Industries</span><span>, 2023</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c439174f05dbbf75463cb7405da62b4a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673358,"asset_id":115194392,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673358/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194392"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194392"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194392; 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Materials \u0026 methods: In vitro potency against Trypanosoma brucei brucei, T. b. rhodesiense, T. cruzi and Leishmania infantum beside cytotoxicity on MRC-5 fibroblasts were determined. Results \u0026 conclusion: Maytenus parviflora showed the highest activity against T. b. brucei (IC 50 of 0.6 μg/ml) and T. b. rhodesiense (IC 50 of 0.5 μg/ml) with low cytotoxicity (CC 50 of 30 μg/ml). Saussurea costus and Commiphora wightii, showed pronounced potency against T. cruzi with an IC 50 of 3.6 and 2.5 μg/ml, respectively. Jatropha pelargonifolia and Solanum villosum exhibited pronounced activity toward L. infantum with an IC 50 of 3.2 and 2.0 μg/ml, respectively. M. parviflora, S. costus, C. wightii, J. pelargonifolia and S. villosum showed relevant selectivity.","publication_date":{"day":null,"month":null,"year":2023,"errors":{}},"publication_name":"Medicinal Plants - International Journal of Phytomedicines and Related Industries","grobid_abstract_attachment_id":111673358},"translated_abstract":null,"internal_url":"https://www.academia.edu/115194392/In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia","translated_internal_url":"","created_at":"2024-02-20T19:58:32.965-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":111673358,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673358/thumbnails/1.jpg","file_name":"fmc-2018-018020240221-1-vejga9.pdf","download_url":"https://www.academia.edu/attachments/111673358/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"In_vitro_antiprotozoal_activity_of_some.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673358/fmc-2018-018020240221-1-vejga9-libre.pdf?1708488632=\u0026response-content-disposition=attachment%3B+filename%3DIn_vitro_antiprotozoal_activity_of_some.pdf\u0026Expires=1733349596\u0026Signature=cAYL-rRX2i5Arnwq70B7aVCVPTOrrlzwJBhWKXc4juTrwxZWfhpE5M4r0A7OnL9hHR7F1kvTUW3TCq6yEV7dUPlYD2YWuLBvCz37BdmtSir8BEDiVVo6mHUPs5s9MLdBQOO5OV9~eyQS5USD8ig2vvpEQN9RgCh8kvdrEmbdYwOOM~Qicmy0eH3DQrqWEa6hmsAtQfKk8a2UcK-fw8ziXoqIScVLErKsCwVo98-e~8aycW~fJr1gdj~GP5j~y46OK9lQfpB4CWRPtBQ0KAnMKV9U-JQDbKs~FDsSUkUDlYQY2WozZN3q833Pa~cTxV15RIj2k2CRTQyzlWhB~8QNDw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"In_vitro_antiprotozoal_activity_of_some_medicinal_plants_methanolic_extracts_against_Entamoeba_histolytica_and_Giardia_lamblia","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":111673358,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673358/thumbnails/1.jpg","file_name":"fmc-2018-018020240221-1-vejga9.pdf","download_url":"https://www.academia.edu/attachments/111673358/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"In_vitro_antiprotozoal_activity_of_some.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673358/fmc-2018-018020240221-1-vejga9-libre.pdf?1708488632=\u0026response-content-disposition=attachment%3B+filename%3DIn_vitro_antiprotozoal_activity_of_some.pdf\u0026Expires=1733349596\u0026Signature=cAYL-rRX2i5Arnwq70B7aVCVPTOrrlzwJBhWKXc4juTrwxZWfhpE5M4r0A7OnL9hHR7F1kvTUW3TCq6yEV7dUPlYD2YWuLBvCz37BdmtSir8BEDiVVo6mHUPs5s9MLdBQOO5OV9~eyQS5USD8ig2vvpEQN9RgCh8kvdrEmbdYwOOM~Qicmy0eH3DQrqWEa6hmsAtQfKk8a2UcK-fw8ziXoqIScVLErKsCwVo98-e~8aycW~fJr1gdj~GP5j~y46OK9lQfpB4CWRPtBQ0KAnMKV9U-JQDbKs~FDsSUkUDlYQY2WozZN3q833Pa~cTxV15RIj2k2CRTQyzlWhB~8QNDw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":59370,"name":"In Vitro","url":"https://www.academia.edu/Documents/in/In_Vitro"},{"id":571342,"name":"Entamoeba histolytica","url":"https://www.academia.edu/Documents/in/Entamoeba_histolytica"},{"id":814097,"name":"Antiprotozoal","url":"https://www.academia.edu/Documents/in/Antiprotozoal"},{"id":1476273,"name":"Giardia","url":"https://www.academia.edu/Documents/in/Giardia"},{"id":4147252,"name":"Giardia lamblia","url":"https://www.academia.edu/Documents/in/Giardia_lamblia"}],"urls":[{"id":39652427,"url":"https://doi.org/10.5958/0975-6892.2023.00010.2"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194373"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194373/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae"><img alt="Research paper thumbnail of Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194373/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae">Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Dec 28, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional med...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194373"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194373"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194373; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194373]").text(description); $(".js-view-count[data-work-id=115194373]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194373; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194373']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194373, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194373]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194373,"title":"Chemical Composition and Antiproliferative and Antioxidant Activities of Methanolic Extract of Alcea setosa A. Malvaceae","translated_title":"","metadata":{"abstract":"Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","publisher":"Diva Enterprises Private Limited","publication_date":{"day":28,"month":12,"year":2021,"errors":{}},"publication_name":"Research journal of pharmacy and technology"},"translated_abstract":"Alcea setosa A. (Malvaceae) is a wild plant that grows in Jordan and have several traditional medicinal uses. This study aims to collect and chemically analyze the methanolic extract from Alcea setosa A. from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). The extract was extracted by methanol solvent and analyzed by liquid chromatography coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. A total of 290 compounds, 12 among which were identified when compared to available standards, the extract contained six flavons derivatives, Two fatty acids, one ketone derivative, one flavonol derivative, one organic acid, and one coumarin derivative. The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, moderate antioxidant activity was observed for the extract in the DPPH scavenging activity test. To sum up, this study indicates that samples of A. setosa collected from Jordan is likely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","internal_url":"https://www.academia.edu/115194373/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae","translated_internal_url":"","created_at":"2024-02-20T19:57:32.265-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Methanolic_Extract_of_Alcea_setosa_A_Malvaceae","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":22050,"name":"Cytotoxicity","url":"https://www.academia.edu/Documents/in/Cytotoxicity"},{"id":103339,"name":"Antioxidant","url":"https://www.academia.edu/Documents/in/Antioxidant"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":1164053,"name":"PHARMACY TECHNOLOGY","url":"https://www.academia.edu/Documents/in/PHARMACY_TECHNOLOGY"},{"id":1335152,"name":"Viability assay","url":"https://www.academia.edu/Documents/in/Viability_assay"}],"urls":[{"id":39652416,"url":"https://doi.org/10.52711/0974-360x.2021.01115"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194372"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae"><img alt="Research paper thumbnail of Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae">Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Jan 25, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essent...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194372"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194372"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194372; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194372]").text(description); $(".js-view-count[data-work-id=115194372]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194372; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194372']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194372, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194372]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194372,"title":"Chemical Composition and Antiproliferative and Antioxidant Activities of Essential Oil from Juniperus phoenicea L. Cupressaceae","translated_title":"","metadata":{"abstract":"Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","publisher":"Diva Enterprises Private Limited","publication_date":{"day":25,"month":1,"year":2022,"errors":{}},"publication_name":"Research journal of pharmacy and technology"},"translated_abstract":"Being multipurpose, relatively safe, and widely favorable for consumption, interest in the essential oils of medicinal plants has been increasing. Essential oil (EO) of Juniperus phoenicea is traditionally used for treatment of several health problems such as diabetes, rheumatism, and cancer that is the second leading cause of death in Jordan. This study aims to collect and chemically analyze EO from Juniperus phoenicea L., from Jordan and to evaluate its cytotoxic and antioxidant activity against human breast cancer cells (T47D), colorectal adenocarcinoma cells (CACO2), and normal human fibroblasts (MRC5). EO was extracted by hydro-distillation and analyzed in a gas chromatograph coupled with a mass spectrometer. Cell viability was assessed using trypan blue, neutral red, and MTT assays, and antioxidant activity was evaluated using DPPH scavenging activity assay. Chemical composition analysis revealed 23 constituents in the EO, and the amount of α- pinene was the highest (69.71%). The results also revealed that the IC50 values of the viability assays were higher among normal cells compared to the human cancer cell lines, and the viability inhibition was significant at higher concentrations compared to untreated cells. Nevertheless, low antioxidant activity was observed for the oil in the DPPH scavenging activity test. To sum up, this study indicates that Jordanian Juniperus phoenicea EO, albeit unlikely to be an effective antioxidant, is optimistically potential to be utilized in breast and colon cancers treatment due to its preferential cytotoxicity against cancer cells.","internal_url":"https://www.academia.edu/115194372/Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae","translated_internal_url":"","created_at":"2024-02-20T19:57:32.024-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Chemical_Composition_and_Antiproliferative_and_Antioxidant_Activities_of_Essential_Oil_from_Juniperus_phoenicea_L_Cupressaceae","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":48465,"name":"Essential Oil","url":"https://www.academia.edu/Documents/in/Essential_Oil"},{"id":103339,"name":"Antioxidant","url":"https://www.academia.edu/Documents/in/Antioxidant"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":1164053,"name":"PHARMACY TECHNOLOGY","url":"https://www.academia.edu/Documents/in/PHARMACY_TECHNOLOGY"},{"id":1335152,"name":"Viability assay","url":"https://www.academia.edu/Documents/in/Viability_assay"}],"urls":[{"id":39652415,"url":"https://doi.org/10.52711/0974-360x.2022.00025"}]}, dispatcherData: dispatcherData }); 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The composition of the flowering wild plants has been studied, field trips have been conducted to the area and collections of any available plant materials with emphasis on vascular flowering plants have been made. The results revealed a high botanical diversity of the area in terms of the number of plant species recorded. A total number of 71 species has been recorded belongs to 69 genera and 38 families. This number of plant species represents 35% of the total flora of the entire Petra area/Wadi Musa. Moreover, some recorded species are considered as endemic to the area such as the elegant Iris of Petra (Iris petrana) or the medicinal rare Globularia arabica, Galium petrae and Verbascum petrae. A number of historical economic trees have been found in the study area like the old Quercus coccifera, Pistacia atlantica, Amygdalus korschinskyii, Ficus sycomorus and Juniperus phoenica. Other recorded species are both palatable and medicinal like Achillea fragrantissima, Artemisia herba-alba, Peganum harmala, Paronychia argentea and many others. However, the majority of plant species recorded in the study area are facing the danger of loss and degradation, as the area is severely exposed to either man impact or environmental damaging factors. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194367"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194367/Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review"><img alt="Research paper thumbnail of Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194367/Investigating_the_Anti_Viral_and_Anti_Bacterial_activities_of_Jordanian_Medicinal_plants_A_narrative_review">Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review</a></div><div class="wp-workCard_item"><span>Research journal of pharmacy and technology</span><span>, Jan 25, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientifi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientific literature. The challenge of disease and death caused by infectious diseases like viruses and bacteria, and as infectious diseases evolve and pathogens develop resistance to existing pharmaceuticals, the search for new novel leads, possibly with different modes of action, against bacterial and viral diseases has intensified in recent years. The intent of this review is to provide prevalent information on the antibacterial and antiviral potential in medicinal plants in Jordan, mode of action, type of viruses and bacteria, and phytochemical contents. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194364"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194364/Induction_of_apoptosis_by_Ruta_chalepensis_L_essential_oil_in_human_breast_cancer_cells_MCF_7_"><img alt="Research paper thumbnail of Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)" class="work-thumbnail" src="https://attachments.academia-assets.com/111673355/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194364/Induction_of_apoptosis_by_Ruta_chalepensis_L_essential_oil_in_human_breast_cancer_cells_MCF_7_">Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Pharmacognosy Research</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Context: Recent scientific studies have reported that essential oils induce apoptosis in various ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (EO) of Ruta chalepensis L. against MCF-7 cell line. Methods: Cytotoxicity was determined using methyl thiazol tetrazolium assay. The apoptotic activity of EO was analyzed using annexin V-fluorescein isothiocyanate/propidium iodide binding flow cytometry. The cell morphology was inspected under an inverted microscope. DAPI staining assay was used for the morphological observation. Activation of caspases-3/7, -8, and-9 was assessed using a caspase assay kit. Results: Ruta chalepensis essential oil significantly inhibited the proliferation of MCF-7 cells at 72 h. Moreover, the results showed that cell death is associated with the apoptotic process, and the number of apoptotic cells was significantly increased in the groups treated with EO than ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="65950bbdd7daca388323e9e9eb347d4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673355,"asset_id":115194364,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673355/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194364"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194364"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194364; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194364]").text(description); $(".js-view-count[data-work-id=115194364]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194364; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194364']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194364, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "65950bbdd7daca388323e9e9eb347d4c" } } $('.js-work-strip[data-work-id=115194364]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194364,"title":"Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)","translated_title":"","metadata":{"abstract":"Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (EO) of Ruta chalepensis L. against MCF-7 cell line. Methods: Cytotoxicity was determined using methyl thiazol tetrazolium assay. The apoptotic activity of EO was analyzed using annexin V-fluorescein isothiocyanate/propidium iodide binding flow cytometry. The cell morphology was inspected under an inverted microscope. DAPI staining assay was used for the morphological observation. Activation of caspases-3/7, -8, and-9 was assessed using a caspase assay kit. Results: Ruta chalepensis essential oil significantly inhibited the proliferation of MCF-7 cells at 72 h. Moreover, the results showed that cell death is associated with the apoptotic process, and the number of apoptotic cells was significantly increased in the groups treated with EO than ...","publisher":"Garval Editorial Ltda.","publication_name":"Journal of Pharmacy \u0026amp; Pharmacognosy Research"},"translated_abstract":"Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (EO) of Ruta chalepensis L. against MCF-7 cell line. Methods: Cytotoxicity was determined using methyl thiazol tetrazolium assay. The apoptotic activity of EO was analyzed using annexin V-fluorescein isothiocyanate/propidium iodide binding flow cytometry. The cell morphology was inspected under an inverted microscope. DAPI staining assay was used for the morphological observation. Activation of caspases-3/7, -8, and-9 was assessed using a caspase assay kit. Results: Ruta chalepensis essential oil significantly inhibited the proliferation of MCF-7 cells at 72 h. Moreover, the results showed that cell death is associated with the apoptotic process, and the number of apoptotic cells was significantly increased in the groups treated with EO than 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Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant"},{"id":1235612,"name":"DAPI","url":"https://www.academia.edu/Documents/in/DAPI"},{"id":1335070,"name":"Mcf","url":"https://www.academia.edu/Documents/in/Mcf"},{"id":1335154,"name":"Propidium Iodide","url":"https://www.academia.edu/Documents/in/Propidium_Iodide"},{"id":3101476,"name":"Annexin","url":"https://www.academia.edu/Documents/in/Annexin"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194363"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194363/Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_"><img alt="Research paper thumbnail of Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)" class="work-thumbnail" src="https://attachments.academia-assets.com/111673352/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194363/Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_">Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Pharmacognosy Research</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jord...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jordan and neighboring countries. Aims: To evaluate the cytotoxic potential of ethanolic and aqueous extracts from the aerial parts of A. orientalis against three cell lines MCF-7, Caco-2, and HDFa. In addition to assessing the total phenolic and flavonoid contents, antioxidant activity. Further to analyze the phytochemical constituents. Methods: The phytochemical analysis was performed using gas chromatography/mass spectrometry. The total phenolic (TPC) and flavonoid (TFC) contents were assessed using colorimetric methods. The antioxidant properties of both extracts were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power ability. Cytotoxicity was investigated using methyl thiazol tetrazolium (MTT) assay. Results: The most abundant compounds in the extract were 9-octadecenoic acid, methyl ester, (E)- (27.2%), hexadecanoic acid, methyl ester (12...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="600add623fd3a68a4cd91cc1007faa87" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673352,"asset_id":115194363,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673352/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194363"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194363"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194363; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194363]").text(description); $(".js-view-count[data-work-id=115194363]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194363; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194363']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194363, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "600add623fd3a68a4cd91cc1007faa87" } } $('.js-work-strip[data-work-id=115194363]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194363,"title":"Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)","translated_title":"","metadata":{"abstract":"Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jordan and neighboring countries. Aims: To evaluate the cytotoxic potential of ethanolic and aqueous extracts from the aerial parts of A. orientalis against three cell lines MCF-7, Caco-2, and HDFa. In addition to assessing the total phenolic and flavonoid contents, antioxidant activity. Further to analyze the phytochemical constituents. Methods: The phytochemical analysis was performed using gas chromatography/mass spectrometry. The total phenolic (TPC) and flavonoid (TFC) contents were assessed using colorimetric methods. The antioxidant properties of both extracts were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power ability. Cytotoxicity was investigated using methyl thiazol tetrazolium (MTT) assay. Results: The most abundant compounds in the extract were 9-octadecenoic acid, methyl ester, (E)- (27.2%), hexadecanoic acid, methyl ester (12...","publisher":"Garval Editorial Ltda.","ai_title_tag":"Antioxidant and Cytotoxic Assessment of Ajuga orientalis Extracts","publication_name":"Journal of Pharmacy \u0026amp; Pharmacognosy Research"},"translated_abstract":"Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jordan and neighboring countries. Aims: To evaluate the cytotoxic potential of ethanolic and aqueous extracts from the aerial parts of A. orientalis against three cell lines MCF-7, Caco-2, and HDFa. In addition to assessing the total phenolic and flavonoid contents, antioxidant activity. Further to analyze the phytochemical constituents. Methods: The phytochemical analysis was performed using gas chromatography/mass spectrometry. The total phenolic (TPC) and flavonoid (TFC) contents were assessed using colorimetric methods. The antioxidant properties of both extracts were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power ability. Cytotoxicity was investigated using methyl thiazol tetrazolium (MTT) assay. Results: The most abundant compounds in the extract were 9-octadecenoic acid, methyl ester, (E)- (27.2%), hexadecanoic acid, methyl ester (12...","internal_url":"https://www.academia.edu/115194363/Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_","translated_internal_url":"","created_at":"2024-02-20T19:57:30.095-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":111673352,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/111673352/thumbnails/1.jpg","file_name":"jppres22.1344_10.3.486.pdf","download_url":"https://www.academia.edu/attachments/111673352/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Chemical_composition_in_vitro_assessment.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/111673352/jppres22.1344_10.3.486-libre.pdf?1708488633=\u0026response-content-disposition=attachment%3B+filename%3DChemical_composition_in_vitro_assessment.pdf\u0026Expires=1733349597\u0026Signature=gSEFJZ7eySCNEGlnLMNuQ1R3lZzMGi2MtBKcHkjA6dh8SpaWVaEvSFWTrDoxbOvHddAKZUiBwvWDgNyiaAWBqqE9MLgGBDCSgYSk9XBExFf86qtDVj3F3rXXW56avdcfV7Qlvh9xIQ1PMjJmlgXfDa0c~Y5cOxzX~PIZoAhhbEF3erooWNt85nl1AJ7gMaarV6NNU~GWmR8DoOZhlwrc52IOnqwzHRLJEUhsEnAysqccko8Ero9fOwnPOjg7eszGk~M59PSWxNfOWf3YgUwNfuNMFIkJF6l61iuRdbe~4LSbMJwiyNRo4hinEky0pjnNF4NVgUlvnZCFe0uxlOCqXw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Chemical_composition_in_vitro_assessment_of_antioxidant_properties_and_cytotoxicity_activity_of_ethanolic_and_aqueous_extracts_of_Ajuga_orientalis_L_Lamiaceae_","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan 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Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":22050,"name":"Cytotoxicity","url":"https://www.academia.edu/Documents/in/Cytotoxicity"},{"id":44297,"name":"Herbal Medicine","url":"https://www.academia.edu/Documents/in/Herbal_Medicine"},{"id":51711,"name":"Antioxidants","url":"https://www.academia.edu/Documents/in/Antioxidants"},{"id":52939,"name":"Herbal medicines","url":"https://www.academia.edu/Documents/in/Herbal_medicines"},{"id":59404,"name":"Lamiaceae","url":"https://www.academia.edu/Documents/in/Lamiaceae"},{"id":67648,"name":"GC-MS","url":"https://www.academia.edu/Documents/in/GC-MS"},{"id":73418,"name":"Medicinal plants and natural 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Pharmacology","url":"https://www.academia.edu/Documents/in/Medicinal_Plant_Pharmacology"},{"id":1322481,"name":"Antioxidant Capacity","url":"https://www.academia.edu/Documents/in/Antioxidant_Capacity"},{"id":2272583,"name":"MTT assay","url":"https://www.academia.edu/Documents/in/MTT_assay"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194362"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/115194362/Cinchona_officinalis_Cinchona_Tree_and_Corylus_avellana_Common_Hazel_"><img alt="Research paper thumbnail of Cinchona officinalis (Cinchona Tree) and Corylus avellana (Common Hazel)" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/115194362/Cinchona_officinalis_Cinchona_Tree_and_Corylus_avellana_Common_Hazel_">Cinchona officinalis (Cinchona Tree) and Corylus avellana (Common Hazel)</a></div><div class="wp-workCard_item"><span>CRC Press eBooks</span><span>, May 9, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194362"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194362"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194362; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194362]").text(description); $(".js-view-count[data-work-id=115194362]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194362; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194362']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194362, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194362]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194362,"title":"Cinchona officinalis (Cinchona Tree) and Corylus avellana (Common Hazel)","translated_title":"","metadata":{"publisher":"Informa","publication_date":{"day":9,"month":5,"year":2022,"errors":{}},"publication_name":"CRC Press eBooks"},"translated_abstract":null,"internal_url":"https://www.academia.edu/115194362/Cinchona_officinalis_Cinchona_Tree_and_Corylus_avellana_Common_Hazel_","translated_internal_url":"","created_at":"2024-02-20T19:57:29.946-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Cinchona_officinalis_Cinchona_Tree_and_Corylus_avellana_Common_Hazel_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants"},{"id":878506,"name":"Quinine","url":"https://www.academia.edu/Documents/in/Quinine"},{"id":3489148,"name":"Quinidine","url":"https://www.academia.edu/Documents/in/Quinidine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194361"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats"><img alt="Research paper thumbnail of Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats">Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats</a></div><div class="wp-workCard_item"><span>Heliyon</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P &amp;lt; 0.05) and increased the fibroblast&amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194361"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194361"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194361; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194361]").text(description); $(".js-view-count[data-work-id=115194361]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194361; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194361']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194361, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194361]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194361,"title":"Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats","translated_title":"","metadata":{"abstract":"Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P \u0026amp;lt; 0.05) and increased the fibroblast\u0026amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.","publisher":"Elsevier BV","publication_name":"Heliyon"},"translated_abstract":"Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Globularia arabica and Malva sylvestris leaves and Rhus coriaria fruits. plant extracts were orally administered to the rats to determine their effect on the wound-healing process. Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P \u0026amp;lt; 0.05) and increased the fibroblast\u0026amp;#39;s proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.","internal_url":"https://www.academia.edu/115194361/Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats","translated_internal_url":"","created_at":"2024-02-20T19:57:29.715-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Efficacy_of_methanolic_extracts_of_some_medicinal_plants_on_wound_healing_in_diabetic_rats","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus"},{"id":350937,"name":"Fibroblast","url":"https://www.academia.edu/Documents/in/Fibroblast"}],"urls":[{"id":39652408,"url":"https://api.elsevier.com/content/article/PII:S2405844022013597?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194359"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats"><img alt="Research paper thumbnail of Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats">Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats</a></div><div class="wp-workCard_item"><span>Journal of Cosmetic Dermatology</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">AimThis study assessed the effects of topical application of R. coriaria extract on the rate of w...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194359"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194359"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194359; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194359]").text(description); $(".js-view-count[data-work-id=115194359]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194359; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194359']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194359, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=115194359]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194359,"title":"Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non‐diabetic rats","translated_title":"","metadata":{"abstract":"AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Journal of Cosmetic Dermatology"},"translated_abstract":"AimThis study assessed the effects of topical application of R. coriaria extract on the rate of wound closure. The rate of wound contraction was used to assess the wound healing efficacy of the R. coriaria fruit methanolic extract.MethodsUsing excision and burn model of wound repair in diabetic male Wistar rats. Also, hydroxyproline, collagen content, and proinflammatory and anti‐inflammatory cytokines levels were determined in this study.ResultsDuring the early wound healing phase, interleukin 6 (IL‐6) levels were found to be decreased by R. coriaria treatment and increased the level of interleukin 10 (IL‐10). Increased wound contraction augmented with hydroxyproline and collagen content, supporting the early wound healing exhibited by R. coriaria. The epithelialization, neovascularization and enhanced hydroxyproline and collagen expression were strongly associated with the healing pattern.ConclusionThis study indicating that R. coriaria methanolic fruit extract has a potent wound ...","internal_url":"https://www.academia.edu/115194359/Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats","translated_internal_url":"","created_at":"2024-02-20T19:57:29.314-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Effect_of_Rhus_coriaria_L_methanolic_fruit_extract_on_wound_healing_in_diabetic_and_non_diabetic_rats","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[],"research_interests":[{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":88216,"name":"Cosmetic Dermatology","url":"https://www.academia.edu/Documents/in/Cosmetic_Dermatology"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":802828,"name":"Hydroxyproline","url":"https://www.academia.edu/Documents/in/Hydroxyproline"}],"urls":[{"id":39652407,"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jocd.14668"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194358"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194358/Assessment_of_the_antibacterial_effects_of_Moringa_peregrina_extracts"><img alt="Research paper thumbnail of Assessment of the antibacterial effects of Moringa peregrina extracts" class="work-thumbnail" src="https://attachments.academia-assets.com/111673336/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194358/Assessment_of_the_antibacterial_effects_of_Moringa_peregrina_extracts">Assessment of the antibacterial effects of Moringa peregrina extracts</a></div><div class="wp-workCard_item"><span>African Journal of Microbiology Research</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="948a908740abd6ceafc2cd9c8931dd00" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673336,"asset_id":115194358,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673336/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194358"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194358"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194358; 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The effect of plant extracts were tested against three bacterial species: Escherichia coli (E. coli ATCC25922), Staphylococcus aureus (S. aureus ATCC 43300) and Klebsiella pneumoniae (K. pneumoniae ATCC 13883). M. peregrina ethanolic extracts showed significant antibacterial effect on the three tested bacterial strains using the disc diffusion method. The inhibition zones caused by leaf ethanolic extracts were 14 to 30, 8 to 19 and 9 to 22 mm in diameter against E. coli, K. pneumonia, and S. aureus, respectively. Root ethanolic extracts showed inhibition zones as 18 to 42, 44 to 59 and 34 to 45 mm in diameter against E. coli, K. pneumonia, and S. aureus, respectively. Seed extract caused inhibitory zones of 16 to 38, 6 to 32 and 6 to 18 mm in diameter against E. coli, K. pneumonia and S. aureus, respectively. The results showed that the zones of inhibition for the three bacterial species increased in a dose dependant manner and that the M.peregrina root ethanolic extract exhibited more potent inhibition. The other test done to assess the antibacterial effect of M. peregrina ethanolic extracts was the minimum inhibitory concentrations (MIC). Such test was conducted on the same three bacterial species, where the MIC for the M. peregrina leaf extract for E. coli, K. pneumoniae, and S. aureus were 12.0, 15.0 and 18 mg/ml, respectively. The MIC for seed ethanolic extract was 13.0 and 7.0 mg/ml against E. coli, K. pneumoniae and S. aureus respectively. Also, the MIC for root ethanolic extract of M. peregrine against E. coli, K. pneumoniae and S. aureus was 9.0, 3, 2, and 5 mg/ml, respectively. Such low MIC values especially for the root extract represent strong potential for M. peregrina as an antibacterial agent.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"African Journal of Microbiology 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194357/Micropropagation_of_the_Wild_Endangered_Daffodil_Narcissus_Tazetta_L">Micropropagation of the Wild Endangered Daffodil Narcissus Tazetta L</a></div><div class="wp-workCard_item"><span>Acta Horticulturae</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="da81e53eeeb43b52ab1e4eccf6edb2b1" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673346,"asset_id":115194357,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673346/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action 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It is an endangered and medicinal plant grown in Jordan and neighboring countries. A protocol has been developed for efficient rapid micropropagation of Narcissus tazetta through adventitious shoot induction. One type of explant has been used which is multi bulb scale explants. Field-derived material was successfully sterilised using 70% ethanol for 3 mins. and 1% NaOCl for 20 mins followed by hot water treatment for 1 hour at 54 o C before dissecting out bulb scales. The results showed that high adventitious shoot formation was obtained by supplementing the culture medium with high ratio concentration of BAP to low NAA concentration, which are (0.0, 44.4 µM) for T4 and (2.7, 44.4µM) for T7. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="115194298"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/115194298/Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud"><img alt="Research paper thumbnail of Ruta Graveolens, Peganum Harmala and Citrullus Colocynthis Methanolic Extracts Have in Vitro Protoscolocidal Effects and Act Against Bacteria Isolated From Echinococcal Hydatid Cyst Fliud" class="work-thumbnail" src="https://attachments.academia-assets.com/111673322/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/115194298/Ruta_Graveolens_Peganum_Harmala_and_Citrullus_Colocynthis_Methanolic_Extracts_Have_in_Vitro_Protoscolocidal_Effects_and_Act_Against_Bacteria_Isolated_From_Echinococcal_Hydatid_Cyst_Fliud">Ruta Graveolens, Peganum Harmala and Citrullus Colocynthis Methanolic Extracts Have in Vitro Protoscolocidal Effects and Act Against Bacteria Isolated From Echinococcal Hydatid Cyst Fliud</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Echinococcosis is a common and endemic disease that affects both humans and animals. In this stud...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. The most effective...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c21b0ae0342a7cf33bc1c024cfd7c6eb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":111673322,"asset_id":115194298,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/111673322/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="115194298"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="115194298"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 115194298; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=115194298]").text(description); $(".js-view-count[data-work-id=115194298]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 115194298; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='115194298']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 115194298, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c21b0ae0342a7cf33bc1c024cfd7c6eb" } } $('.js-work-strip[data-work-id=115194298]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":115194298,"title":"Ruta Graveolens, Peganum Harmala and Citrullus Colocynthis Methanolic Extracts Have in Vitro Protoscolocidal Effects and Act Against Bacteria Isolated From Echinococcal Hydatid Cyst Fliud","translated_title":"","metadata":{"abstract":"Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. The most effective...","publisher":"Research Square Platform LLC","publication_date":{"day":null,"month":null,"year":2022,"errors":{}}},"translated_abstract":"Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of Ruta graveolens, Peganum harmala aerial parts, and Citrullus colocynthis seeds against protoscolosis and isolated bacterial strains from hydatid cysts were assessed using disc diffusion methos and Minimum Inhibitory Concentration (MIC). The chemical composition of aerial sections of R. graveolensand P. harmala, as well as methanolic extracts of C. colocynthis seeds, was studied using LC-MS. These plants produced a total of 26, 31, and 23 chemicals, respectively. The bacteria listed below were isolated from hydatid cyst fluid collected from a variety of sick locations, including the lung and liver. Micrococcus spp., E. coli, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter amnigenus, Pseudomonas aeruginosa, Staphylococcus xylosus, and Achromobacter xylosoxidans are among the bacteria that have been identified. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111349553"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan"><img alt="Research paper thumbnail of Flora of Bader Al-Jadida County, western high mountains of Amman city/Jordan" class="work-thumbnail" src="https://attachments.academia-assets.com/108914893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan">Flora of Bader Al-Jadida County, western high mountains of Amman city/Jordan</a></div><div class="wp-workCard_item"><span>International Journal of Herbal Medicine</span><span>, Oct 1, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="84bd70df476a52df040a5f6d895b0bca" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108914893,"asset_id":111349553,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111349553"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111349553"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111349553; 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The flowering plant specimen have been collected from the area and identified. A number of 259 species and 2 subspecies belong to 179 genera and 44 families are recorded. Photographs of some selected common plant species in the study area as well as photographs for some natural views are demonstrated, with emphasis on the topography of the heights that are dominated by forest stands of typically Mediterranean vegetation elements of mixed evergreen and deciduous oak trees of Quercus coccifera and Q. ithaburensis, Amygdalus communis, Crataegus aronia and Pyrus syriaca, shrubs and cultivated tress like, grape vines, Olive trees, fig trees (Ficus indica), pomegranate trees (Punica granatum) and mulberries trees (Morus alba and M. nigra). The study area is blessed by lots of aromatic plant species like Lonicera etrusca, Calicotome villosa, Thymus capitatus, Varthemia iphionoides, Narcissus tazetta and others, orchid species, Mentha aquatica and others. Lots of medicinal plants are also recorded in the study area, that are still used in folk medicine by the local people like Varthemia iphionoides, Arum palaestinum, Vinca herbacea, Dittrichia viscosa,, Achillea santolina, Bongardia chrysogonum, Thymus capitatus and others. Many recorded species are edible plants like Cyclamen persicum, the shrubby raspberry Rubus sanguineous, Capparis spinosa, Pyrus syriaca, Crataegus aronia, Gundelia tournefortii, Rhus coriaria, Thymus capitatus, Malva sylvestris and some others. A number of showy, rare and endangered aromatic plant species are recorded like Orchis antolica, Narcissus tazetta, Sternbergia clusiana, Tulipa agenesis, Styrax officinalis and Lonicera etrusca. Few stands of Pistacia atlantica and P. palaestina trees are also recorded.","publication_date":{"day":1,"month":10,"year":2015,"errors":{}},"publication_name":"International Journal of Herbal Medicine","grobid_abstract_attachment_id":108914893},"translated_abstract":null,"internal_url":"https://www.academia.edu/111349553/Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan","translated_internal_url":"","created_at":"2023-12-13T11:12:01.536-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108914893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914893/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914893/3-2-4.1-libre.pdf?1702495232=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=aHhcfLMwm9xaGjVr6~7vs7GK-bQVFkAkpUNjmkkoduNBGyFvjlx8iCn5q2KiBq0LHz9U414MxA3SqCa9VttcdJZ2VJAaGYZjpoIHyoJ5enMuqDvIef8DiXS0YApJeWE5TGQmdUIz3QbAY6qMFqUaID5LCPukGOh1nDU9VDMIy8YN22tXl8lK6XCXk9ULfGVTqEjO~Rf9vnfP7Ani0I7LWQ05vE8IvGvEqwcxVm2KoXEg84hw7UWCrrduQxTp1h2P6r~bJLVg5TIlIrIXpLRtZPxH~llH2~ambBMzFzJvUnK8uoIGJ1fDDLVpWAV5H92odj3rAm4L6yFCGs058LwiWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Flora_of_Bader_Al_Jadida_County_western_high_mountains_of_Amman_city_Jordan","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":108914893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914893/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914893/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914893/3-2-4.1-libre.pdf?1702495232=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=aHhcfLMwm9xaGjVr6~7vs7GK-bQVFkAkpUNjmkkoduNBGyFvjlx8iCn5q2KiBq0LHz9U414MxA3SqCa9VttcdJZ2VJAaGYZjpoIHyoJ5enMuqDvIef8DiXS0YApJeWE5TGQmdUIz3QbAY6qMFqUaID5LCPukGOh1nDU9VDMIy8YN22tXl8lK6XCXk9ULfGVTqEjO~Rf9vnfP7Ani0I7LWQ05vE8IvGvEqwcxVm2KoXEg84hw7UWCrrduQxTp1h2P6r~bJLVg5TIlIrIXpLRtZPxH~llH2~ambBMzFzJvUnK8uoIGJ1fDDLVpWAV5H92odj3rAm4L6yFCGs058LwiWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":108914894,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914894/thumbnails/1.jpg","file_name":"3-2-4.1.pdf","download_url":"https://www.academia.edu/attachments/108914894/download_file","bulk_download_file_name":"Flora_of_Bader_Al_Jadida_County_western.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914894/3-2-4.1-libre.pdf?1702495239=\u0026response-content-disposition=attachment%3B+filename%3DFlora_of_Bader_Al_Jadida_County_western.pdf\u0026Expires=1733349597\u0026Signature=cOQP-KJVoZTAWx7BKYCFdu9g~ut4mCIYmWx1a31yRbW2bH9ttzwAi8KbKz2xRWbEQTKcXPzkyilaJ1R3HabjrP618~pGfhx19NzhXqqM4OrxStcNH87vQ1PjFmwYUxZcGsLA40qkoAqUALNVal3YJTeGM5Al~7Klt1jH52JlTbgW1JWOeBAvnh90i0ojgUMtj2KcfBA1NqJWHEtyi0~vsWt75P5fNI~OaaZ6DLzCsn4jf2Y4pAq0QfvpefpNPPW1EC8bmkr9JDHTdzs98bg80Tihft3VNYksT05I6iP0gD4G8XPd4q-foWj4NqkrYdZ54hBWgz1E6IoLkuW4Yypy2Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":261,"name":"Geography","url":"https://www.academia.edu/Documents/in/Geography"},{"id":44297,"name":"Herbal Medicine","url":"https://www.academia.edu/Documents/in/Herbal_Medicine"}],"urls":[{"id":37034238,"url":"https://www.florajournal.com/archives/2015/vol3issue4/PartA/3-2-4.1.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111349552"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines"><img alt="Research paper thumbnail of Evaluation of the antiproliferative effect of selected plant extracts on colon and skin cancer cell lines" class="work-thumbnail" src="https://attachments.academia-assets.com/108914939/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines">Evaluation of the antiproliferative effect of selected plant extracts on colon and skin cancer cell lines</a></div><div class="wp-workCard_item"><span>journal of applied pharmaceutical science</span><span>, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="45bd73af67e736becb26ae9d3aab94bb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":108914939,"asset_id":111349552,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111349552"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111349552"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111349552; 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The selected plants are Varthemia iphionoides (Asteraceae), Micromeria myrtifolia (Lamiaceae), Micromeria nervosa (Lamiaceae), Origanum dayi (Lamiaceae), Ajuga chia (Lamiaceae), Salvia palaestina (Lamiaceae), and Bongardia chrysogonum (Berberidaceae). The results showed that M. nervosa and O. dayi exhibited antiproliferative activity against Caco-2 cancer cell line, with half-maximal inhibitory concentrations (IC 50) that equal 98 ± 2.5 and 73.6 ± 3.4 μg/ml, respectively. Furthermore, A. chia, B. chrysogonum, and O. dayi exhibited antiproliferative activity against the WM136-1A cancer cell line, with IC 50 that equals 400 ± 5.1, 98.1 ± 3.2, and 245 ± 3.6 μg/ml, respectively. None of the extracts had an effect on fibroblast cells at any used concentration. In conclusion, the extracts of M. nervosa, O. dayi, A. chia, and B. chrysogonum showed promising antiproliferative potential and can be good candidates for the development of novel anticancerous agents.","publication_date":{"day":null,"month":null,"year":2022,"errors":{}},"publication_name":"journal of applied pharmaceutical science","grobid_abstract_attachment_id":108914939},"translated_abstract":null,"internal_url":"https://www.academia.edu/111349552/Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines","translated_internal_url":"","created_at":"2023-12-13T11:12:01.343-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":10876832,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108914939,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914939/thumbnails/1.jpg","file_name":"3759_pdf.pdf","download_url":"https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Evaluation_of_the_antiproliferative_effe.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914939/3759_pdf-libre.pdf?1702495241=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_of_the_antiproliferative_effe.pdf\u0026Expires=1733349597\u0026Signature=EAXGNZS~3F6PuCu0v2EJZo5COgpdlPAZGz3ZEge5gTTDOXrf4eGbJ6R53bN-l-jlDT2k-WujKKqVdWy6AI0VIZDIWcD20s3y7tA7yZkIbFXPl75b8FqZgGRPVDhSEPRvCVGXhguSnriz47G5Qx3JplW8y-dZL3nTHfVY1NZv3cMP91pYd0H3i-ZK2CxPbQjuPqVUiO-S6Lt2ahS3CxF0DgqZllVrfKpnJHhPyNVpitZvbModiYpy82efELriwfyRfsh~NsQAdLbRGejraQbUyarW~NfV9uA1liiUbGcvbJ5sht2XjJ2RT5ZKf04IOnjjTbS9iISIn7~W397P7M4isg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Evaluation_of_the_antiproliferative_effect_of_selected_plant_extracts_on_colon_and_skin_cancer_cell_lines","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":10876832,"first_name":"Sawsan","middle_initials":null,"last_name":"Oran","page_name":"SawsanOran","domain_name":"ju-jo","created_at":"2014-04-06T21:25:59.348-07:00","display_name":"Sawsan Oran","url":"https://ju-jo.academia.edu/SawsanOran"},"attachments":[{"id":108914939,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108914939/thumbnails/1.jpg","file_name":"3759_pdf.pdf","download_url":"https://www.academia.edu/attachments/108914939/download_file?st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&st=MTczMzM0NTk5Nyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Evaluation_of_the_antiproliferative_effe.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108914939/3759_pdf-libre.pdf?1702495241=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_of_the_antiproliferative_effe.pdf\u0026Expires=1733349597\u0026Signature=EAXGNZS~3F6PuCu0v2EJZo5COgpdlPAZGz3ZEge5gTTDOXrf4eGbJ6R53bN-l-jlDT2k-WujKKqVdWy6AI0VIZDIWcD20s3y7tA7yZkIbFXPl75b8FqZgGRPVDhSEPRvCVGXhguSnriz47G5Qx3JplW8y-dZL3nTHfVY1NZv3cMP91pYd0H3i-ZK2CxPbQjuPqVUiO-S6Lt2ahS3CxF0DgqZllVrfKpnJHhPyNVpitZvbModiYpy82efELriwfyRfsh~NsQAdLbRGejraQbUyarW~NfV9uA1liiUbGcvbJ5sht2XjJ2RT5ZKf04IOnjjTbS9iISIn7~W397P7M4isg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine"},{"id":37292,"name":"Colorectal cancer","url":"https://www.academia.edu/Documents/in/Colorectal_cancer"}],"urls":[{"id":37034237,"url":"https://doi.org/10.7324/japs.2022.121110"}]}, dispatcherData: dispatcherData }); 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