Search results for: Silymarin.

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Silymarin.</title> <meta name="description" content="Search results for: Silymarin."> <meta name="keywords" content="Silymarin."> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Silymarin."> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 3</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Silymarin.</h1> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Hepatoprotective Activity of Sharbat Deenar, against Carbon Tetrachloride-Induced Hepatotoxicity in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=Nazmul%20Huda">Nazmul Huda</a>, <a href="https://publications.waset.org/search?q=Ashik%20Mosaddik"> Ashik Mosaddik</a>, <a href="https://publications.waset.org/search?q=Abdul%20Awal"> Abdul Awal</a>, <a href="https://publications.waset.org/search?q=Shafiqur%20Rahman"> Shafiqur Rahman</a>, <a href="https://publications.waset.org/search?q=Rukhsana%20Shaheen"> Rukhsana Shaheen</a>, <a href="https://publications.waset.org/search?q=Mustofa%20Nabi"> Mustofa Nabi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>Polyherbal formulation <em>Sharbat Deenar</em> is a very popular unani medicine in Bangladesh. It is usually used for different kinds of liver disorders. In absence of reliable and inadequate hepatoprotective agents in conventional medicine, the herbal preparations are preferred for liver diseases. The present study was designed to evaluate the hepatoprotective activity of <em>Sharbat Deenar </em>on carbon tetrachloride (CCl<sub>4</sub>) induced hepatotoxicity in male Long-Evans albino rats. Group I served as normal control and received neither formulation nor carbon tetrachloride. Group II received only CCl<sub>4</sub> 1mL/kg body weight of rat intraperitoneally for consecutive 14 days. Group III received CCl<sub>4</sub> 1mL/kg body weight of rat intraperitoneally and <em>Silymarin</em>, in dose 50mg/kg body weight of rat orally. Group IV received CCl<sub>4</sub> 1mL/kg body weight of rat intraperitoneally and <em>Sharbat Deenar </em>1mL/kg body weight of rat for the same 14 consecutive days. At the end of the study, hepatoprotective activity was evaluated by the levels of total bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP). Histopathological study of rat liver was also carried out. The results showed that polyherbal formulation <em>Sharbat Deenar </em>exhibited a significant hepatoprotective effect. Such an outcome seems to be the synergistic effect of all ingredients of tested herbal formulation. Although this study suggests that <em>Sharbat Deenar </em>may be used to cure or minimize various liver diseases, it needs further study to attain the clarity of mechanism and safety.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Carbon%20tetrachloride" title="Carbon tetrachloride">Carbon tetrachloride</a>, <a href="https://publications.waset.org/search?q=Hepatoprotective" title=" Hepatoprotective"> Hepatoprotective</a>, <a href="https://publications.waset.org/search?q=Sharbat%20Deenar" title=" Sharbat Deenar"> Sharbat Deenar</a>, <a href="https://publications.waset.org/search?q=Silymarin." title=" Silymarin. "> Silymarin. </a> </p> <a href="https://publications.waset.org/10008784/hepatoprotective-activity-of-sharbat-deenar-against-carbon-tetrachloride-induced-hepatotoxicity-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10008784/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10008784/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10008784/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10008784/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10008784/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10008784/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10008784/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10008784/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10008784/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10008784/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10008784.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">881</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Antioxidative Potential of Aqueous Extract of Ocimum americanum L. Leaves: An in vitro and in vivo Evaluation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=B.%20T.%20Aluko">B. T. Aluko</a>, <a href="https://publications.waset.org/search?q=O.%20I.%20Oloyede"> O. I. Oloyede</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>Ocimum americanum L (Lamiaceae) is an annual herb that is native to tropical Africa. The in vitro and in vivo antioxidant activity of its aqueous extract was carefully investigated by assessing the DPPH radical scavenging activity, ABTS radical scavenging activity and hydrogen peroxide radical scavenging activity. The reducing power, total phenol, total flavonoids and flavonols content of the extract were also evaluated. The data obtained revealed that the extract is rich in polyphenolic compounds and scavenged the radicals in a concentration dependent manner. This was done in comparison with the standard antioxidants such as BHT and Vitamin C. Also, the induction of oxidative damage with paracetamol (2000 mg/kg) resulted in the elevation of lipid peroxides and significant (P < 0.05) decrease in activities of superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase in the liver and kidney of rats. However, the pretreatment of rats with aqueous extract of O. americanum leaves (200 and 400 mg/kg) and silymarin (100 mg/kg) caused a significant (P < 0.05) reduction in the values of lipid peroxides and restored the levels of antioxidant parameters in these organs. These findings suggest that the leaves of O. americanum have potent antioxidant properties which may be responsible for its acclaimed folkloric uses.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Antioxidants" title="Antioxidants">Antioxidants</a>, <a href="https://publications.waset.org/search?q=free%20radicals" title=" free radicals"> free radicals</a>, <a href="https://publications.waset.org/search?q=Ocimum%20americanum" title=" Ocimum americanum"> Ocimum americanum</a>, <a href="https://publications.waset.org/search?q=scavenging%20activity." title=" scavenging activity."> scavenging activity.</a> </p> <a href="https://publications.waset.org/10000584/antioxidative-potential-of-aqueous-extract-of-ocimum-americanum-l-leaves-an-in-vitro-and-in-vivo-evaluation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10000584/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10000584/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10000584/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10000584/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10000584/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10000584/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10000584/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10000584/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10000584/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10000584/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10000584.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">2548</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Effect of Genotype, Explant Type and Growth Regulators on The Accumulation of Flavonoides of (Silybum marianum L.) in In vitro Culture</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=A.%20Pourjabar">A. Pourjabar</a>, <a href="https://publications.waset.org/search?q=S.A.%20Mohammadi"> S.A. Mohammadi</a>, <a href="https://publications.waset.org/search?q=R.%20Ghahramanzadeh"> R. Ghahramanzadeh</a>, <a href="https://publications.waset.org/search?q=Gh.%20Salimi"> Gh. Salimi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>The extract of milk thistle contains a mix of flavonolignans termed silymarine.. In order to analysis influence of growth regulators, genotype, explant and subculture on the accumulation of flavonolignans, a study was carried out by using two genotype (Budakalszi and Noor abad moghan cultivars), cotyledon and hypocotyle explants, solid media of MS supplemented by different combinations of two growth regulators; Kinetin (0.1, 1 mg/l) and 2,4-D (1, 2 mg/l). Seeds of the plant were germinated in MS media whitout growth regulators in growth chamber at 26°C and darkness condition. In order to callus induction, the culture media was supplemented whit different concentrations of 2,4-D and kinetin. Calli obtained from explants were sub-cultured four times into the fresh media of the first experiment. flavonoides was extracted from calli in four subcultures. The flavonoid components were determined by high- performance liquid choromatography (HPLC) and separated into Taxifolin, Silydianin+Silychristin, Silybin A+B and Isosilybin A+B. Results showed that with increasing callus age, increased accumulation of silybin A+B, but reduced Isosilybin A+B content. Highest accumulation of Taxifolin was observed at first calli. Calli produced from cotyledon explant of Budakalszi cultivar were superior for Silybin A+B, where calli from hypocotyl explant produced higher amount of Taxifolin and Silydianin+Silychristin. The best cultivar for Silymarin production in this study was Budakalszi cultivar. High amount of SBN A+B and TXF were obtained from hypocotil explant.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Callus%20culture" title="Callus culture">Callus culture</a>, <a href="https://publications.waset.org/search?q=Flavonolignans" title=" Flavonolignans"> Flavonolignans</a>, <a href="https://publications.waset.org/search?q=Silimarine" title=" Silimarine"> Silimarine</a> </p> <a href="https://publications.waset.org/6131/effect-of-genotype-explant-type-and-growth-regulators-on-the-accumulation-of-flavonoides-of-silybum-marianum-l-in-in-vitro-culture" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/6131/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/6131/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/6131/chicago" target="_blank" rel="nofollow" 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Search results for: Silymarin.