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Improvement of Antibacterial Activity for Ceftazidime by Partially Purified Tannase from Penicillium expansum
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<div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 87351</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Improvement of Antibacterial Activity for Ceftazidime by Partially Purified Tannase from Penicillium expansum</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sahira%20N.%20Muslim">Sahira N. Muslim</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20N.%20Mohammed"> Alaa N. Mohammed</a>, <a href="https://publications.waset.org/abstracts/search?q=Saba%20Saadoon%20Khazaal"> Saba Saadoon Khazaal</a>, <a href="https://publications.waset.org/abstracts/search?q=Batool%20Kadham%20Salman"> Batool Kadham Salman</a>, <a href="https://publications.waset.org/abstracts/search?q=Israa%20M.%20S.%20AL-Kadmy"> Israa M. S. AL-Kadmy</a>, <a href="https://publications.waset.org/abstracts/search?q=Sraa%20N.%20Muslim"> Sraa N. Muslim</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20S.%20Dwaish"> Ahmed S. Dwaish</a>, <a href="https://publications.waset.org/abstracts/search?q=Sawsan%20Mohammed%20Kareem"> Sawsan Mohammed Kareem</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarah%20N.%20Aziz"> Sarah N. Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruaa%20A.%20Jasim"> Ruaa A. Jasim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tannase has wide applications in food, beverage, brewing, cosmetics and chemical industries and one of the major applications of tannase is the production of gallic acid. Gallic acid is used for manufacturing of trimethoprim. In the present study, a local fungal strain of <em>Penicillium expansum</em> A<sub>4</sub> isolated from spoilt apple samples gave the highest production level of tannase. Tannase was partially purified with a recovery yield of 92.52% and 6.32 fold of purification by precipitation using ammonium sulfate at 50% saturation. Tannase led to increased antimicrobial activity of ceftazidime against<em> Pseudomonas aeruginosa</em> and<em> S. aureus</em> and had a synergism effect at low concentrations of ceftazidime, and thus, tannase may be a useful adjuvant agent for the treatment of many bacterial infections in combination with ceftazidime. <iframe src="https://publications.waset.org/abstracts/65967.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ceftazidime" title="ceftazidime">ceftazidime</a>, <a href="https://publications.waset.org/abstracts/search?q=Penicillium%20expansum" title=" Penicillium expansum"> Penicillium expansum</a>, <a href="https://publications.waset.org/abstracts/search?q=tannase" title=" tannase"> tannase</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a> </p> <a href="https://publications.waset.org/abstracts/65967/improvement-of-antibacterial-activity-for-ceftazidime-by-partially-purified-tannase-from-penicillium-expansum" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65967.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">741</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational 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