CINXE.COM

<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-toc-available" lang="ja" dir="ltr"> <head> <meta charset="UTF-8"> <title>P糖タンパク質 - Wikipedia</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-toc-available";var cookie=document.cookie.match(/(?:^|; )jawikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"ja", "wgMonthNames":["","1月","2月","3月","4月","5月","6月","7月","8月","9月","10月","11月","12月"],"wgRequestId":"97defd4f-6290-4a8a-8129-6f5503aefdb7","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"P糖タンパク質","wgTitle":"P糖タンパク質","wgCurRevisionId":98227629,"wgRevisionId":98227629,"wgArticleId":1473871,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["すべてのスタブ記事","薬学関連のスタブ項目","ISBNマジックリンクを使用しているページ","薬学","膜輸送体","CD抗原"],"wgPageViewLanguage":"ja","wgPageContentLanguage":"ja","wgPageContentModel":"wikitext","wgRelevantPageName":"P糖タンパク質","wgRelevantArticleId":1473871,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgRedirectedFrom":"P-糖蛋白質","wgNoticeProject":"wikipedia", "wgCiteReferencePreviewsActive":true,"wgMediaViewerOnClick":true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"ja","pageLanguageDir":"ltr","pageVariantFallbacks":"ja"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":true,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":5000,"wgInternalRedirectTargetUrl":"/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA","wgRelatedArticlesCompat":[],"wgCentralAuthMobileDomain":false,"wgEditSubmitButtonLabelPublish":true,"wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q412902","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false, "wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false};RLSTATE={"ext.gadget.PDFLinkIcon":"ready","ext.gadget.RedirectColor":"ready","ext.globalCssJs.user.styles":"ready","site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready","ext.wikimediaBadges":"ready"};RLPAGEMODULES=["mediawiki.action.view.redirect","ext.cite.ux-enhancements","mediawiki.page.media","site","mediawiki.page.ready","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.NormalizeCharWidth","ext.gadget.suppressEnterAtSummaryBox","ext.gadget.checkSignature","ext.gadget.charinsert", "ext.gadget.WikiMiniAtlas","ext.gadget.switcher","ext.gadget.protectionIndicator","ext.urlShortener.toolbar","ext.centralauth.centralautologin","mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init","ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession","wikibase.sidebar.tracking"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=ja&modules=ext.cite.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediaBadges%7Cext.wikimediamessages.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=ja&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=ja&modules=ext.gadget.PDFLinkIcon%2CRedirectColor&only=styles&skin=vector-2022"> <link rel="stylesheet" href="/w/load.php?lang=ja&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.4"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="P糖タンパク質 - Wikipedia"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//ja.m.wikipedia.org/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA"> <link rel="alternate" type="application/x-wiki" title="編集" href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (ja)"> <link rel="EditURI" type="application/rsd+xml" href="//ja.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://ja.wikipedia.org/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.ja"> <link rel="alternate" type="application/atom+xml" title="WikipediaのAtomフィード" href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E6%9C%80%E8%BF%91%E3%81%AE%E6%9B%B4%E6%96%B0&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="//login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-P糖タンパク質 rootpage-P糖タンパク質 skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">コンテンツにスキップ</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="サイト"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="メインメニュー" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">メインメニュー</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">メインメニュー</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">非表示</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> 案内 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage-description" class="mw-list-item"><a href="/wiki/%E3%83%A1%E3%82%A4%E3%83%B3%E3%83%9A%E3%83%BC%E3%82%B8" title="メインページに移動する [z]" accesskey="z"><span>メインページ</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%83%86%E3%82%A3%E3%83%BB%E3%83%9D%E3%83%BC%E3%82%BF%E3%83%AB" title="このプロジェクトについて、できること、情報を入手する場所"><span>コミュニティ・ポータル</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:%E6%9C%80%E8%BF%91%E3%81%AE%E5%87%BA%E6%9D%A5%E4%BA%8B" title="最近の出来事の背景を知る"><span>最近の出来事</span></a></li><li id="n-newpages" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%B0%E3%81%97%E3%81%84%E3%83%9A%E3%83%BC%E3%82%B8" title="最近新規に作成されたページの一覧"><span>新しいページ</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E6%9C%80%E8%BF%91%E3%81%AE%E6%9B%B4%E6%96%B0" title="このウィキにおける最近の更新の一覧 [r]" accesskey="r"><span>最近の更新</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%81%8A%E3%81%BE%E3%81%8B%E3%81%9B%E8%A1%A8%E7%A4%BA" title="無作為に選択されたページを読み込む [x]" accesskey="x"><span>おまかせ表示</span></a></li><li id="n-sandbox" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%82%B5%E3%83%B3%E3%83%89%E3%83%9C%E3%83%83%E3%82%AF%E3%82%B9" title="練習用のページ"><span>練習用ページ</span></a></li><li id="n-commonsupload" class="mw-list-item"><a href="//commons.wikimedia.org/wiki/Special:UploadWizard?uselang=ja" title="画像やメディアファイルをウィキメディア・コモンズにアップロード"><span>アップロード (ウィキメディア・コモンズ)</span></a></li> </ul> </div> </div> <div id="p-help" class="vector-menu mw-portlet mw-portlet-help" > <div class="vector-menu-heading"> ヘルプ </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Help:%E7%9B%AE%E6%AC%A1" title="情報を得る場所"><span>ヘルプ</span></a></li><li id="n-villagepump" class="mw-list-item"><a href="/wiki/Wikipedia:%E4%BA%95%E6%88%B8%E7%AB%AF" title="プロジェクトについての意見交換"><span>井戸端</span></a></li><li id="n-notice" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%81%8A%E7%9F%A5%E3%82%89%E3%81%9B" title="プロジェクトについてのお知らせ"><span>お知らせ</span></a></li><li id="n-bugreportspage" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%83%90%E3%82%B0%E3%81%AE%E5%A0%B1%E5%91%8A" title="ウィキペディア・ソフトウェアのバグ報告"><span>バグの報告</span></a></li><li id="n-contact" class="mw-list-item"><a href="/wiki/Wikipedia:%E9%80%A3%E7%B5%A1%E5%85%88" title="ウィキペディアやウィキメディア財団に関する連絡先"><span>ウィキペディアに関するお問い合わせ</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/%E3%83%A1%E3%82%A4%E3%83%B3%E3%83%9A%E3%83%BC%E3%82%B8" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-ja.svg" style="width: 7.5em; height: 1.25em;"> <img class="mw-logo-tagline" alt="" src="/static/images/mobile/copyright/wikipedia-tagline-ja.svg" width="100" height="14" style="width: 6.25em; height: 0.875em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%A4%9C%E7%B4%A2" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Wikipedia内を検索 [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>検索</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Wikipedia内を検索" aria-label="Wikipedia内を検索" autocapitalize="sentences" title="Wikipedia内を検索 [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="特別:検索"> </div> <button class="cdx-button cdx-search-input__end-button">検索</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="個人用ツール"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="ページのフォントサイズ、幅、色の外観を変更する" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="表示" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">表示</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_ja.wikipedia.org&uselang=ja" class=""><span>寄付</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%82%A2%E3%82%AB%E3%82%A6%E3%83%B3%E3%83%88%E4%BD%9C%E6%88%90&returnto=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="アカウントを作成してログインすることをお勧めしますが、必須ではありません" class=""><span>アカウント作成</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o" class=""><span>ログイン</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="その他の操作" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="個人用ツール" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">個人用ツール</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="利用者メニュー" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_ja.wikipedia.org&uselang=ja"><span>寄付</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%82%A2%E3%82%AB%E3%82%A6%E3%83%B3%E3%83%88%E4%BD%9C%E6%88%90&returnto=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="アカウントを作成してログインすることをお勧めしますが、必須ではありません"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>アカウント作成</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>ログイン</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> ログアウトした編集者のページ <a href="/wiki/Wikipedia:%E3%82%A6%E3%82%A3%E3%82%AD%E3%83%9A%E3%83%87%E3%82%A3%E3%82%A2%E3%81%B8%E3%82%88%E3%81%86%E3%81%93%E3%81%9D" aria-label="編集の詳細"><span>もっと詳しく</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E8%87%AA%E5%88%86%E3%81%AE%E6%8A%95%E7%A8%BF%E8%A8%98%E9%8C%B2" title="このIPアドレスからなされた編集の一覧 [y]" accesskey="y"><span>投稿記録</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%83%88%E3%83%BC%E3%82%AF%E3%83%9A%E3%83%BC%E3%82%B8" title="このIPアドレスからなされた編集についての議論 [n]" accesskey="n"><span>トーク</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="サイト"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目次" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目次</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">非表示</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">ページ先頭</div> </a> </li> <li id="toc-概要" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#概要"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>概要</span> </div> </a> <ul id="toc-概要-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-機能" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#機能"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>機能</span> </div> </a> <ul id="toc-機能-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-構造" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#構造"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>構造</span> </div> </a> <ul id="toc-構造-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-基質" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#基質"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>基質</span> </div> </a> <ul id="toc-基質-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-阻害剤" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#阻害剤"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>阻害剤</span> </div> </a> <ul id="toc-阻害剤-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-出典" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#出典"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>出典</span> </div> </a> <ul id="toc-出典-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目次" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="目次の表示・非表示を切り替え" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">目次の表示・非表示を切り替え</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">P糖タンパク質</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="特定の記事の別の言語版に移動します。利用可能な言語17件" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-17" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">17の言語版</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86_%D8%B3%D9%83%D8%B1%D9%8A-P" title="アラビア語: بروتين سكري-P" lang="ar" hreflang="ar" data-title="بروتين سكري-P" data-language-autonym="العربية" data-language-local-name="アラビア語" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/MDR1" title="チェコ語: MDR1" lang="cs" hreflang="cs" data-title="MDR1" data-language-autonym="Čeština" data-language-local-name="チェコ語" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Multidrug-Resistance-Protein_1" title="ドイツ語: Multidrug-Resistance-Protein 1" lang="de" hreflang="de" data-title="Multidrug-Resistance-Protein 1" data-language-autonym="Deutsch" data-language-local-name="ドイツ語" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/P-glycoprotein" title="英語: P-glycoprotein" lang="en" hreflang="en" data-title="P-glycoprotein" data-language-autonym="English" data-language-local-name="英語" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Glucoprote%C3%ADna-P" title="スペイン語: Glucoproteína-P" lang="es" hreflang="es" data-title="Glucoproteína-P" data-language-autonym="Español" data-language-local-name="スペイン語" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%D8%B1%D9%88%D8%AA%D8%A6%DB%8C%D9%86_%D9%BE%DB%8C%E2%80%8C%D8%AC%DB%8C%E2%80%8C%D9%BE%DB%8C" title="ペルシア語: پروتئین پی‌جی‌پی" lang="fa" hreflang="fa" data-title="پروتئین پی‌جی‌پی" data-language-autonym="فارسی" data-language-local-name="ペルシア語" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Glycoprot%C3%A9ine_P" title="フランス語: Glycoprotéine P" lang="fr" hreflang="fr" data-title="Glycoprotéine P" data-language-autonym="Français" data-language-local-name="フランス語" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/P-glicoproteina" title="イタリア語: P-glicoproteina" lang="it" hreflang="it" data-title="P-glicoproteina" data-language-autonym="Italiano" data-language-local-name="イタリア語" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/P-%D0%B3%D0%BB%D0%B8%D0%BA%D0%BE%D0%B1%D0%B5%D0%BB%D0%BA%D0%BE%D0%B2%D0%B8%D0%BD%D0%B0" title="マケドニア語: P-гликобелковина" lang="mk" hreflang="mk" data-title="P-гликобелковина" data-language-autonym="Македонски" data-language-local-name="マケドニア語" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/P-glycoprote%C3%AFne" title="オランダ語: P-glycoproteïne" lang="nl" hreflang="nl" data-title="P-glycoproteïne" data-language-autonym="Nederlands" data-language-local-name="オランダ語" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Glikoproteina_P" title="ポーランド語: Glikoproteina P" lang="pl" hreflang="pl" data-title="Glikoproteina P" data-language-autonym="Polski" data-language-local-name="ポーランド語" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Glicoprote%C3%ADna-P" title="ポルトガル語: Glicoproteína-P" lang="pt" hreflang="pt" data-title="Glicoproteína-P" data-language-autonym="Português" data-language-local-name="ポルトガル語" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/P-%D0%B3%D0%BB%D0%B8%D0%BA%D0%BE%D0%BF%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD" title="ロシア語: P-гликопротеин" lang="ru" hreflang="ru" data-title="P-гликопротеин" data-language-autonym="Русский" data-language-local-name="ロシア語" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/P-glikoprotein" title="セルボ・クロアチア語: P-glikoprotein" lang="sh" hreflang="sh" data-title="P-glikoprotein" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="セルボ・クロアチア語" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Glikoprotein_P" title="スロベニア語: Glikoprotein P" lang="sl" hreflang="sl" data-title="Glikoprotein P" data-language-autonym="Slovenščina" data-language-local-name="スロベニア語" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/P-glikoprotein" title="セルビア語: P-glikoprotein" lang="sr" hreflang="sr" data-title="P-glikoprotein" data-language-autonym="Српски / srpski" data-language-local-name="セルビア語" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/ABCB1" title="ウクライナ語: ABCB1" lang="uk" hreflang="uk" data-title="ABCB1" data-language-autonym="Українська" data-language-local-name="ウクライナ語" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q412902#sitelinks-wikipedia" title="言語間リンクを編集" class="wbc-editpage">リンクを編集</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="名前空間"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="本文を閲覧 [c]" accesskey="c"><span>ページ</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/%E3%83%8E%E3%83%BC%E3%83%88:P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" rel="discussion" title="本文ページについての議論 [t]" accesskey="t"><span>ノート</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="別の言語に切り替える" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">日本語</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="表示"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA"><span>閲覧</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit" title="このページのソースコードを編集する [e]" accesskey="e"><span>編集</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=history" title="このページの過去の版 [h]" accesskey="h"><span>履歴表示</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="ページツール"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="ツール" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">ツール</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">ツール</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">非表示</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="その他の操作" > <div class="vector-menu-heading"> 操作 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA"><span>閲覧</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit" title="このページのソースコードを編集する [e]" accesskey="e"><span>編集</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=history"><span>履歴表示</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> 全般 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%83%AA%E3%83%B3%E3%82%AF%E5%85%83/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="ここにリンクしている全ウィキページの一覧 [j]" accesskey="j"><span>リンク元</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E9%96%A2%E9%80%A3%E3%83%9A%E3%83%BC%E3%82%B8%E3%81%AE%E6%9B%B4%E6%96%B0%E7%8A%B6%E6%B3%81/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" rel="nofollow" title="このページからリンクしているページの最近の更新 [k]" accesskey="k"><span>関連ページの更新状況</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB%E3%81%AE%E3%82%A2%E3%83%83%E3%83%97%E3%83%AD%E3%83%BC%E3%83%89" title="ファイルをアップロードする [u]" accesskey="u"><span>ファイルをアップロード</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E7%89%B9%E5%88%A5%E3%83%9A%E3%83%BC%E3%82%B8%E4%B8%80%E8%A6%A7" title="特別ページの一覧 [q]" accesskey="q"><span>特別ページ</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&oldid=98227629" title="このページのこの版への固定リンク"><span>この版への固定リンク</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=info" title="このページについての詳細情報"><span>ページ情報</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%81%93%E3%81%AE%E3%83%9A%E3%83%BC%E3%82%B8%E3%82%92%E5%BC%95%E7%94%A8&page=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&id=98227629&wpFormIdentifier=titleform" title="このページの引用方法"><span>このページを引用</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:UrlShortener&url=https%3A%2F%2Fja.wikipedia.org%2Fwiki%2FP%25E7%25B3%2596%25E3%2582%25BF%25E3%2583%25B3%25E3%2583%2591%25E3%2582%25AF%25E8%25B3%25AA"><span>短縮URLを取得する</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:QrCode&url=https%3A%2F%2Fja.wikipedia.org%2Fwiki%2FP%25E7%25B3%2596%25E3%2582%25BF%25E3%2583%25B3%25E3%2583%2591%25E3%2582%25AF%25E8%25B3%25AA"><span>QRコードをダウンロード</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> 印刷/書き出し </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%96%E3%83%83%E3%82%AF&bookcmd=book_creator&referer=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA"><span>ブックの新規作成</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:DownloadAsPdf&page=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=show-download-screen"><span>PDF 形式でダウンロード</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&printable=yes" title="このページの印刷用ページ [p]" accesskey="p"><span>印刷用バージョン</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> 他のプロジェクト </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:P-glycoprotein" hreflang="en"><span>コモンズ</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q412902" title="関連付けられたデータリポジトリ項目へのリンク [g]" accesskey="g"><span>ウィキデータ項目</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="ページツール"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">表示</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">非表示</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">出典: フリー百科事典『ウィキペディア（Wikipedia）』</div> </div> <div id="contentSub"><div id="mw-content-subtitle"><span class="mw-redirectedfrom">（<a href="/w/index.php?title=P-%E7%B3%96%E8%9B%8B%E7%99%BD%E8%B3%AA&redirect=no" class="mw-redirect" title="P-糖蛋白質">P-糖蛋白質</a>から転送）</span></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ja" dir="ltr"><p><b>P糖タンパク質</b>（Pとうタンパクしつ、<a href="/wiki/%E8%8B%B1%E8%AA%9E" title="英語">英</a>: <span lang="en">P-glycoprotein, P-gp, Pgp</span>）は、<a href="/wiki/%E5%88%86%E5%AD%90%E9%87%8F" title="分子量">分子量</a>約18万の<a href="/wiki/%E3%83%AA%E3%83%B3%E9%85%B8%E5%8C%96" title="リン酸化">リン酸化</a><a href="/wiki/%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="タンパク質">タンパク質</a>であり、<a href="/wiki/%E7%B4%B0%E8%83%9E%E8%86%9C" title="細胞膜">細胞膜</a>上に存在して<a href="/wiki/%E7%B4%B0%E8%83%9E%E6%AF%92%E6%80%A7" title="細胞毒性">細胞毒性</a>を有する化合物などの細胞外排出を行う。P-gpは<a href="/wiki/%E8%83%BD%E5%8B%95%E8%BC%B8%E9%80%81#ABC輸送体" title="能動輸送">ABC輸送体</a>のMDR/TAPサブファミリーに属する分子であり、腸や肺、腎臓の<a href="/wiki/%E8%BF%91%E4%BD%8D%E5%B0%BF%E7%B4%B0%E7%AE%A1" title="近位尿細管">近位尿細管</a>、<a href="/wiki/%E8%A1%80%E6%B6%B2%E8%84%B3%E9%96%A2%E9%96%80" title="血液脳関門">血液脳関門</a>の<a href="/wiki/%E6%AF%9B%E7%B4%B0%E8%A1%80%E7%AE%A1" title="毛細血管">毛細血管</a><a href="/wiki/%E5%86%85%E7%9A%AE%E7%B4%B0%E8%83%9E" title="内皮細胞">内皮細胞</a>等に発現している。また、P-gpによる薬物の排出は<a href="/wiki/%E8%96%AC%E5%89%A4%E8%80%90%E6%80%A7" title="薬剤耐性">薬剤耐性</a>の形成に寄与している。P-gpは<b>ABCB1</b>（ATP-binding Cassette Sub-family B Member 1）、あるいは<b>MDR1</b>（Multiple drug resistance 1）とも呼ばれる。細胞表面<a href="/wiki/%E6%8A%97%E5%8E%9F" title="抗原">抗原</a>の分類に用いられる<a href="/wiki/CD%E5%88%86%E9%A1%9E" title="CD分類">CD分類</a>ではP-gpはCD243と番号が振られている。なお、名称頭文字の"P"はその薬剤透過性を変化させる働きから"Permeability（透過性）"に基づいてつけられた<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="概要"><span id=".E6.A6.82.E8.A6.81"></span>概要</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=1" title="節を編集: 概要"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>1976年に、多剤耐性関与たんぱく質としてがん細胞から分離された。その後、消化管上皮細胞の管腔側膜に局在することが確認され、血液脳関門、血液精巣関門、血液胎盤関門にも存在したことから、<a href="/wiki/%E7%94%9F%E4%BD%93%E7%95%B0%E7%89%A9" title="生体異物">生体異物</a>への暴露への防御機能を担う重要なたんぱく質との認識がなされるようになった。ヒトP糖タンパク質の遺伝子<i>MDR1</i>/<i>ABCB1</i>は、1986年に単離され<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>、様々な構造の抗癌剤を細胞外へ排出することが明らかになった<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>。その後薬物により誘導されるストレスたんぱく質であることが、抗がん剤や<a href="/wiki/%E3%83%AA%E3%83%95%E3%82%A1%E3%83%B3%E3%83%94%E3%82%B7%E3%83%B3" title="リファンピシン">リファンピシン</a>や<a href="/wiki/%E3%82%A2%E3%82%B9%E3%83%94%E3%83%AA%E3%83%B3" class="mw-redirect" title="アスピリン">アスピリン</a>などに誘導されることから、明らかになった。<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="機能"><span id=".E6.A9.9F.E8.83.BD"></span>機能</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=2" title="節を編集: 機能"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure typeof="mw:File/Thumb"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Function_of_P-glycoprotein.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Function_of_P-glycoprotein.png/250px-Function_of_P-glycoprotein.png" decoding="async" width="250" height="250" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Function_of_P-glycoprotein.png/375px-Function_of_P-glycoprotein.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Function_of_P-glycoprotein.png/500px-Function_of_P-glycoprotein.png 2x" data-file-width="600" data-file-height="600" /></a><figcaption>P-gpは細胞膜上にあり、抗がん剤の細胞外排出などに寄与する。</figcaption></figure> <p>P-gpは<i>MDR1</i>/<i>ABCB1</i><a href="/wiki/%E9%81%BA%E4%BC%9D%E5%AD%90" title="遺伝子">遺伝子</a>産物であり、<a href="/wiki/%E3%82%A2%E3%83%87%E3%83%8E%E3%82%B7%E3%83%B3%E4%B8%89%E3%83%AA%E3%83%B3%E9%85%B8" title="アデノシン三リン酸">アデノシン三リン酸</a>（ATP）のエネルギー依存的に<a href="/wiki/%E7%96%8E%E6%B0%B4%E6%80%A7" title="疎水性">疎水性</a>化合物の細胞外排出を行う輸送体タンパク質である。P-gpをコードする遺伝子は7q21に位置し、28個のエキソンから構成される。腫瘍細胞は薬物に曝される事によりP-gpの発現が亢進し、薬剤耐性となる。また、悪性腫瘍細胞でなくともP-gpを発現している細胞もあり、薬物の排出に寄与している。 </p> <div class="mw-heading mw-heading2"><h2 id="構造"><span id=".E6.A7.8B.E9.80.A0"></span>構造</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=3" title="節を編集: 構造"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-gpは12回膜貫通型の<a href="/wiki/%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="糖タンパク質">糖タンパク質</a>であり、1280個のアミノ酸から構成される。<a href="/wiki/%E3%82%A2%E3%83%9F%E3%83%8E%E5%9F%BA" class="mw-redirect" title="アミノ基">アミノ基</a>側末端及び<a href="/wiki/%E3%82%AB%E3%83%AB%E3%83%9C%E3%82%AD%E3%82%B7%E3%83%AB%E5%9F%BA" class="mw-redirect" title="カルボキシル基">カルボキシル基</a>側末端は共に細胞内に存在しており、12個ある膜貫通ドメインのうち6つ目と7つ目の間及びカルボキシル基末端にATP結合ドメインを保有している。 </p> <div class="mw-heading mw-heading2"><h2 id="基質"><span id=".E5.9F.BA.E8.B3.AA"></span>基質</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=4" title="節を編集: 基質"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P糖タンパク質により排出される物質には以下のようなものがある。 </p> <ul><li>各種<a href="/wiki/%E6%8A%97%E3%82%AC%E3%83%B3%E5%89%A4" class="mw-redirect" title="抗ガン剤">抗ガン剤</a></li> <li><a href="/wiki/%E3%82%B3%E3%83%AB%E3%83%92%E3%83%81%E3%83%B3" title="コルヒチン">コルヒチン</a>や<a href="/wiki/%E3%82%BF%E3%82%AF%E3%83%AD%E3%83%AA%E3%83%A0%E3%82%B9" title="タクロリムス">タクロリムス</a>などの薬剤</li> <li>脂質</li> <li>ペプチド</li> <li>ステロイド</li> <li><a href="/wiki/%E3%83%93%E3%83%AA%E3%83%AB%E3%83%93%E3%83%B3" title="ビリルビン">ビリルビン</a></li> <li><a href="/wiki/%E5%BC%B7%E5%BF%83%E9%85%8D%E7%B3%96%E4%BD%93" title="強心配糖体">強心配糖体</a>（<a href="/wiki/%E3%82%B8%E3%82%B4%E3%82%AD%E3%82%B7%E3%83%B3" title="ジゴキシン">ジゴキシン</a>）</li> <li><a href="/wiki/%E6%8A%97%E4%B8%8D%E6%95%B4%E8%84%88%E8%96%AC" title="抗不整脈薬">抗不整脈薬</a>（<a href="/wiki/%E3%82%AD%E3%83%8B%E3%82%B8%E3%83%B3" title="キニジン">キニジン</a>、<a href="/wiki/%E3%83%99%E3%83%A9%E3%83%91%E3%83%9F%E3%83%AB" title="ベラパミル">ベラパミル</a>）</li> <li><a href="/wiki/%E5%85%8D%E7%96%AB%E6%8A%91%E5%88%B6%E5%89%A4" title="免疫抑制剤">免疫抑制剤</a></li> <li>抗<a href="/wiki/%E3%83%92%E3%83%88%E5%85%8D%E7%96%AB%E4%B8%8D%E5%85%A8%E3%82%A6%E3%82%A4%E3%83%AB%E3%82%B9" title="ヒト免疫不全ウイルス">HIV</a>薬</li></ul> <div class="mw-heading mw-heading2"><h2 id="阻害剤"><span id=".E9.98.BB.E5.AE.B3.E5.89.A4"></span>阻害剤</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=5" title="節を編集: 阻害剤"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-gpの阻害剤である<a href="/wiki/%E3%82%BE%E3%82%B9%E3%82%AD%E3%83%80%E3%83%AB" title="ゾスキダル">ゾスキダル</a>などは、薬剤耐性を克服し抗がん剤の効果を高める薬剤として治験が行われている。 </p> <div class="mw-heading mw-heading2"><h2 id="出典"><span id=".E5.87.BA.E5.85.B8"></span>出典</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit&section=6" title="節を編集: 出典"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol class="references"> <li id="cite_note-1"><b><a href="#cite_ref-1">^</a></b> <span class="reference-text">Juliano RL, Ling V."A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants" Biochim Biophys Acta. 1976 Nov 11;455(1):152-62 <style data-mw-deduplicate="TemplateStyles:r101121245">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation.cs-ja1 q,.mw-parser-output .citation.cs-ja2 q{quotes:"「""」""『""』"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:var(--color-success,#3a3);margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style><a href="/wiki/PMID_(%E8%AD%98%E5%88%A5%E5%AD%90)" class="mw-redirect" title="PMID (識別子)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/990323/">990323</a></span> </li> <li id="cite_note-2"><b><a href="#cite_ref-2">^</a></b> <span class="reference-text">Chen, C.-j., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., and Roninson, I. B. Internal dupilication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistance human cells. Cell, 47: 381-389 (1986)</span> </li> <li id="cite_note-3"><b><a href="#cite_ref-3">^</a></b> <span class="reference-text">Ueda, K., Cardarelli, C., Gottesman, M. M., and Pastan, I. Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. USA, 84: 3004-3008 (1987)</span> </li> <li id="cite_note-4"><b><a href="#cite_ref-4">^</a></b> <span class="reference-text">Kohji Takara,Masayuki Tsujimotoa,Noriaki Ohnishi,Teruyoshi Yokoyama 『Digoxin Up-Regulates MDR1 in Human Colon Carcinoma Caco-2 Cells 』 Biochemical and Biophysical Research Communications　Volume 292, Issue 1, 22 March 2002, P．190</span> </li> </ol> <ul><li><a href="/wiki/%E4%BB%8A%E5%A0%80%E5%92%8C%E5%8F%8B" title="今堀和友">今堀和友</a>、<a href="/wiki/%E5%B1%B1%E5%B7%9D%E6%B0%91%E5%A4%AB" title="山川民夫">山川民夫</a> 編集『生化学辞典第4版』東京化学同人 2007年 <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%87%E7%8C%AE%E8%B3%87%E6%96%99/9784807906703" class="internal mw-magiclink-isbn">ISBN 978-4-8079-0670-3</a></li> <li>Tannock IF,Hill RP,Bristow RG and Harrington L.『がんのベーシックサイエンス日本語版第3版』メディカル･サイエンス･インターナショナル 2006年 <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%87%E7%8C%AE%E8%B3%87%E6%96%99/4895924602" class="internal mw-magiclink-isbn">ISBN 4-89592-460-2</a></li> <li>田中千賀子、加藤隆一編集『NEW薬理学第4版』南江堂 2002年 <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%87%E7%8C%AE%E8%B3%87%E6%96%99/9784524220830" class="internal mw-magiclink-isbn">ISBN 978-4-524-22083-0</a></li></ul> <style data-mw-deduplicate="TemplateStyles:r96783592">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox{font-size:90%}.mw-parser-output .asbox-note{font-size:90%}.mw-parser-output .asbox .navbar{position:absolute;top:-0.90em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:FlattenedRoundPills.jpg" class="mw-file-description"><img alt="スタブアイコン" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/FlattenedRoundPills.jpg/48px-FlattenedRoundPills.jpg" decoding="async" width="48" height="36" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/FlattenedRoundPills.jpg/72px-FlattenedRoundPills.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/00/FlattenedRoundPills.jpg/96px-FlattenedRoundPills.jpg 2x" data-file-width="2048" data-file-height="1536" /></a></span></td><td><p class="asbox-body">この項目は、<a href="/wiki/%E8%96%AC%E5%AD%A6" title="薬学">薬学</a>に関連した<b><a href="/wiki/Wikipedia:%E3%82%B9%E3%82%BF%E3%83%96" title="Wikipedia:スタブ">書きかけの項目</a></b>です。<a class="external text" href="https://ja.wikipedia.org/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&action=edit">この項目を加筆・訂正</a>などしてくださる<a href="/wiki/Category:%E8%96%AC%E5%AD%A6%E9%96%A2%E9%80%A3%E3%81%AE%E3%82%B9%E3%82%BF%E3%83%96%E9%A0%85%E7%9B%AE" title="Category:薬学関連のスタブ項目">協力者を求めています</a>（<a href="/wiki/%E3%83%97%E3%83%AD%E3%82%B8%E3%82%A7%E3%82%AF%E3%83%88:%E8%96%AC%E5%AD%A6" title="プロジェクト:薬学">プロジェクト:薬学</a>／<a href="/wiki/Portal:%E5%8C%BB%E5%AD%A6%E3%81%A8%E5%8C%BB%E7%99%82" title="Portal:医学と医療">Portal:医学と医療</a>/<a href="/wiki/Portal:%E5%8C%96%E5%AD%A6" title="Portal:化学">Portal:化学</a>）。</p></td></tr></tbody></table><style data-mw-deduplicate="TemplateStyles:r99966302">.mw-parser-output .hlist ul,.mw-parser-output .hlist ol{padding-left:0}.mw-parser-output .hlist li,.mw-parser-output .hlist dd,.mw-parser-output .hlist dt{margin-right:0;display:inline-block;white-space:nowrap}.mw-parser-output .hlist dt:after,.mw-parser-output .hlist dd:after,.mw-parser-output .hlist li:after{white-space:normal}.mw-parser-output .hlist li:after,.mw-parser-output .hlist dd:after{content:" ·\a0 ";font-weight:bold}.mw-parser-output .hlist dt:after{content:": "}.mw-parser-output .hlist-pipe dd:after,.mw-parser-output .hlist-pipe li:after{content:" |\a0 ";font-weight:normal}.mw-parser-output .hlist-hyphen dd:after,.mw-parser-output .hlist-hyphen li:after{content:" -\a0 ";font-weight:normal}.mw-parser-output .hlist-comma dd:after,.mw-parser-output .hlist-comma li:after{content:"、";font-weight:normal}.mw-parser-output .hlist-slash dd:after,.mw-parser-output .hlist-slash li:after{content:" /\a0 ";font-weight:normal}.mw-parser-output .hlist dd:last-child:after,.mw-parser-output .hlist dt:last-child:after,.mw-parser-output .hlist li:last-child:after{content:none}.mw-parser-output .hlist dd dd:first-child:before,.mw-parser-output .hlist dd dt:first-child:before,.mw-parser-output .hlist dd li:first-child:before,.mw-parser-output .hlist dt dd:first-child:before,.mw-parser-output .hlist dt dt:first-child:before,.mw-parser-output .hlist dt li:first-child:before,.mw-parser-output .hlist li dd:first-child:before,.mw-parser-output .hlist li dt:first-child:before,.mw-parser-output .hlist li li:first-child:before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child:after,.mw-parser-output .hlist dd dt:last-child:after,.mw-parser-output .hlist dd li:last-child:after,.mw-parser-output .hlist dt dd:last-child:after,.mw-parser-output .hlist dt dt:last-child:after,.mw-parser-output .hlist dt li:last-child:after,.mw-parser-output .hlist li dd:last-child:after,.mw-parser-output .hlist li dt:last-child:after,.mw-parser-output .hlist li li:last-child:after{content:")\a0 ";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li:before{content:" "counter(listitem)" ";white-space:nowrap}.mw-parser-output .hlist dd ol>li:first-child:before,.mw-parser-output .hlist dt ol>li:first-child:before,.mw-parser-output .hlist li ol>li:first-child:before{content:" ("counter(listitem)" "}</style><style data-mw-deduplicate="TemplateStyles:r96787822">.mw-parser-output .navbar{display:inline;font-size:75%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}.mw-parser-output .infobox .navbar{font-size:88%}.mw-parser-output .navbox .navbar{display:block;font-size:88%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}</style><div class="navbar plainlinks hlist"><ul><li class="nv-view"><a href="/wiki/Template:Pharm-stub" title="Template:Pharm-stub"><span title="参照先のページを表示します。">表示</span></a></li><li class="nv-edit"><a class="external text" href="https://ja.wikipedia.org/w/index.php?title=Template:Pharm-stub&action=edit"><span title="参照先のページを編集します。">編集</span></a></li></ul></div></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">「<a dir="ltr" href="https://ja.wikipedia.org/w/index.php?title=P糖タンパク質&oldid=98227629">https://ja.wikipedia.org/w/index.php?title=P糖タンパク質&oldid=98227629</a>」から取得</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%82%AB%E3%83%86%E3%82%B4%E3%83%AA" title="特別:カテゴリ">カテゴリ</a>: <ul><li><a href="/wiki/Category:%E8%96%AC%E5%AD%A6" title="Category:薬学">薬学</a></li><li><a href="/wiki/Category:%E8%86%9C%E8%BC%B8%E9%80%81%E4%BD%93" title="Category:膜輸送体">膜輸送体</a></li><li><a href="/wiki/Category:CD%E6%8A%97%E5%8E%9F" title="Category:CD抗原">CD抗原</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">隠しカテゴリ: <ul><li><a href="/wiki/Category:%E3%81%99%E3%81%B9%E3%81%A6%E3%81%AE%E3%82%B9%E3%82%BF%E3%83%96%E8%A8%98%E4%BA%8B" title="Category:すべてのスタブ記事">すべてのスタブ記事</a></li><li><a href="/wiki/Category:%E8%96%AC%E5%AD%A6%E9%96%A2%E9%80%A3%E3%81%AE%E3%82%B9%E3%82%BF%E3%83%96%E9%A0%85%E7%9B%AE" title="Category:薬学関連のスタブ項目">薬学関連のスタブ項目</a></li><li><a href="/wiki/Category:ISBN%E3%83%9E%E3%82%B8%E3%83%83%E3%82%AF%E3%83%AA%E3%83%B3%E3%82%AF%E3%82%92%E4%BD%BF%E7%94%A8%E3%81%97%E3%81%A6%E3%81%84%E3%82%8B%E3%83%9A%E3%83%BC%E3%82%B8" title="Category:ISBNマジックリンクを使用しているページ">ISBNマジックリンクを使用しているページ</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> 最終更新 2023年11月29日 (水) 19:31 （日時は<a href="/wiki/%E7%89%B9%E5%88%A5:%E5%80%8B%E4%BA%BA%E8%A8%AD%E5%AE%9A#mw-prefsection-rendering" title="特別:個人設定">個人設定</a>で未設定ならば<a href="/wiki/%E5%8D%94%E5%AE%9A%E4%B8%96%E7%95%8C%E6%99%82" title="協定世界時">UTC</a>）。</li> <li id="footer-info-copyright">テキストは<a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.ja">クリエイティブ・コモンズ表示-継承ライセンス</a>のもとで利用できます。追加の条件が適用される場合があります。詳細については<a class="external text" href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use">利用規約</a>を参照してください。</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy/ja">プライバシー・ポリシー</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:%E3%82%A6%E3%82%A3%E3%82%AD%E3%83%9A%E3%83%87%E3%82%A3%E3%82%A2%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6">ウィキペディアについて</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:%E5%85%8D%E8%B2%AC%E4%BA%8B%E9%A0%85">免責事項</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">行動規範</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">開発者</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/ja.wikipedia.org">統計</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Cookieに関する声明</a></li> <li id="footer-places-mobileview"><a href="//ja.m.wikipedia.org/w/index.php?title=P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">モバイルビュー</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/static/images/footer/wikimedia-button.svg" width="84" height="29" alt="Wikimedia Foundation" loading="lazy"></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/w/resources/assets/poweredby_mediawiki.svg" alt="Powered by MediaWiki" width="88" height="31" loading="lazy"></a></li> </ul> </footer> </div> </div> </div> <div class="vector-settings" id="p-dock-bottom"> <ul></ul> </div><script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.codfw.main-f69cdc8f6-wdqp9","wgBackendResponseTime":135,"wgPageParseReport":{"limitreport":{"cputime":"0.152","walltime":"0.185","ppvisitednodes":{"value":273,"limit":1000000},"postexpandincludesize":{"value":4263,"limit":2097152},"templateargumentsize":{"value":105,"limit":2097152},"expansiondepth":{"value":14,"limit":100},"expensivefunctioncount":{"value":0,"limit":500},"unstrip-depth":{"value":1,"limit":20},"unstrip-size":{"value":7888,"limit":5000000},"entityaccesscount":{"value":0,"limit":400},"timingprofile":["100.00% 156.335 1 -total"," 50.79% 79.403 1 Template:Pharm-stub"," 48.75% 76.210 1 Template:Asbox"," 25.51% 39.878 1 Template:PMID"," 23.62% 36.927 1 Template:Catalog_lookup_link"," 19.18% 29.986 1 Template:Lang-en-short"," 17.72% 27.709 1 Template:Lang-*-short"," 11.20% 17.506 1 Template:ISO639言語名"," 4.70% 7.340 1 Template:Lang"," 2.87% 4.483 2 Template:Yesno-no"]},"scribunto":{"limitreport-timeusage":{"value":"0.068","limit":"10.000"},"limitreport-memusage":{"value":1140759,"limit":52428800}},"cachereport":{"origin":"mw-web.codfw.main-f69cdc8f6-szrlp","timestamp":"20241123134501","ttl":2592000,"transientcontent":false}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"P\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea","url":"https:\/\/ja.wikipedia.org\/wiki\/P%E7%B3%96%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA","sameAs":"http:\/\/www.wikidata.org\/entity\/Q412902","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q412902","author":{"@type":"Organization","name":"\u30a6\u30a3\u30ad\u30e1\u30c7\u30a3\u30a2\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3078\u306e\u8ca2\u732e\u8005"},"publisher":{"@type":"Organization","name":"\u30a6\u30a3\u30ad\u30e1\u30c7\u30a3\u30a2\u8ca1\u56e3","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2008-06-16T12:15:42Z","dateModified":"2023-11-29T19:31:40Z"}</script> </body> </html>