Cases | Premium Pharmacy | Health Library

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<div class="sri-content"> <div class="bookTextSummary"> AF is a 55 yo female forensic chemist who has always taken pride in her healthy lifestyle. She has exercised regularly all her life, and enjoys sports such as tennis, bicycling and strenuous hiking. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660955" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660955">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BJ is a 58 yo woman how is undergoing the novel method of transesophageal echocardiography in preparation for use in determining the correct placement of a central vein catheter for long-term parenteral nutrition. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660974" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660974">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> GM is a 62-year-old architect who has been diagnosed with stage III ovarian cancer. She underwent surgical ovarian debulking and is now about to begin an aggressive chemotherapeutic regimen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660988" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660988">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> KK is a 42 yo Brazilian-born executive who works for Ronald Stump, an internationally famous investments mogul and entrepreneur who mentors (and generously rewards) go-getters like KK. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660959" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660959">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BL is a 71 yo financial advisor on vacation on the gulf coast with his wife of 47 years. It’s been a therapeutic get-away, especially for Mrs. BL who lost her central vision to exudative macular degeneration 18 months ago. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660960" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660960">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BZ is shows up at the hospital where you work. He is a 30 yo computer jock who works for one of the high tech internet companies. He has no history of any health related problems but today he reports that he has been coming in from playing basketball on the company grounds feeling dizzy and thinking he was going to faint. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660967" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660967">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> FP is a 63 yo physician practicing in a rural, sparsely populated county in northeast Arkansas. While he works two days a week out of a clinic in one of his county’s larger communities, he is on the road the other three days, often driving long distances to see patients who live in the more remote areas. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660968" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660968">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> FP is a 77-year-old recovering alcoholic who has lived and worked for the past few years with the indigent in a depressed area of Los Angeles. He helps run a soup kitchen and homeless shelter, and is involved in the management of a neighborhood “free clinic” to provide basic health care services to this population. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660990" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660990">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> LM is a 73-year-old man who retired 8 years ago from his job at the downtown public library. Until a few weeks ago, his daily routine consisted of spending the morning with his wife and then taking the bus downtown to his old stomping grounds (he no longer drives an automobile owing to poor eyesight). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660994" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660994">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> MN is a 52-year-old driven and highly successful entrepreneur from Ohio who, seeking warmer climes for his retirement, plans to establish a sailing business in the U.S. Virgin Islands. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660995" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660995">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> MR is an 87 yo widowed female living in a facility designed for healthy seniors capable of independent care. An unusually cold and harsh winter has curtailed the number of field trips and outings that could be planned, but the Activities Director has engaged the residents in many popular indoor events, such as line-dancing, “chairobics” exercise sessions, board games and musical entertainment. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660998" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660998">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> NL is an 84 yo female who had to move to a retirement community after losing her husband to prolonged battle with cancer. She desperately misses her home and the life they shared there, and the move was made all the more devastating because of the need to find good homes for their beloved cats. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661014" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661014">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> VR, a 45-year-old, white female, finally achieved a life-long desire to visit Africa and go on Safari. A month after she returned to the States, VR complained of anorexia, headache, and fatigue that were followed by paroxysms of fever, chills, and rigor. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661021" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661021">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> You often eat lunch with your favorite grandma who is 85 years old and generally in good health except for infrequent bouts of gout. Over the last couple of years when you meet with her you have noticed that she has been gaining weight around her middle and that her legs and ankles seem to be puffy. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661024" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661024">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> Your neighbor, GY, is the 67-year-old patriarch of a large and gregarious family with an unfortunate history of cardiovascular disease. GY is 5’10” and weighs 240 pounds. He is a smoker, and spends most of his life relaxing on the deck of his Sarasota, FL beach home. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660953" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660953">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BB is a 78 yo holy man living on the Apache reservation in western Arizona. Like too many of his heritage, he is diabetic, and the limited formulary at the reservation’s health center provides him with tolbutamide to control his blood sugar levels. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660954" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660954">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BB, a 27-year-old, male attorney, was diagnosed with the HIV virus last year and is currently asymptomatic. He is undergoing treatment with zidovudine (100 mg q4h). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660956" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660956">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> BJ is a Las Vegas blackjack dealer. He is a 38-year-old Caucasian man who has mild intermittent asthma treated with inhaled albuterol for occasional exacerbations. He works nights and sleeps during the day. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660965" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660965">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> Dr. IG is an endocrinologist with a 27-year-old, female patient who has just become pregnant. The patient was diagnosed with Grave disease about 6 months ago and is currently undergoing antithyroid therapy with methimazole (drug 1). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660966" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660966">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> FC is a 28-year-old woman with a history of anorexia and bulimia. She was in therapy for these serious eating disorders until she finished high school and was then a member of a bulimia support group during college, but she has not seen a counselor for almost 6 years. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660970" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660970">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> GB is a bright 76-year-old female who complains to her doctor that recently her bones ache terribly, especially in the morning. She states that she has always had “good bones” and has faithfully taken calcium supplements in the form of chocolate chews (calcium carbonate). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660982" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660982">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> JM is a 56-year-old female who works the counter at a neighborhood diner that specializes in really good cheeseburgers, fries, malts, and homemade pies. Moderately obese, JM knows she shouldn't eat lunch at the diner every day, but she just can't seem to help herself. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660987" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660987">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> KG is a 73 yo single retired bank executive living in Paris who is in the early stages of Alzheimer’s Disease. She began therapy with tacrine HCl four months ago (Cognex, currently taking 20 mg four times a day) and it seems to be halting the advancement of dementia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660999" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660999">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> NW is a 27-year-old male who married his childhood sweetheart 2 years ago and moved to Vermont to open a bed and breakfast. They love each other very much, but are having some difficulties owing to NW's lack of interest in sexual relations. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661001" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661001">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> PB is your favorite grandma and you are her favorite grandchild. She is 78 yo this weekend and you are visiting her at the nursing home where they are celebrating her birthday with a small party. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661004" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661004">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> PQ is a 45 yo mother of 4 healthy young children. He husband died suddenly 6 months ago from a heart attack. PQ’s husband was a patent lawyer and left her and the children in an adequate financial state. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661010" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661010">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> ST is a 68 yo female who traded in her stressful job as an academic administrator at a major academic health center for the relaxed life of Southern California. Heading to “wine country” with her cats, retirement funds and a few family heirlooms, she purposefully sought a new life, making new friends and doing the things she loves most. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661015" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661015">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> WH.-L is a 62 yo Beijing-born scientist attending an international scientific meeting in your hometown. While delivering his groundbreaking paper on the neuroprotective action of some unique bicyclic molecules he has synthesized, he experienced a very rapid and irregular heart rate followed by a tight, gripping pain in his chest. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661018" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661018">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> You are moonlighting at a local hospital inpatient pharmacy when JB, a 37-year-old nightclub owner, is rushed in to the emergency room (ER), unconscious, unresponsive, and breathing shallowly. JB is a locally well-known wheeler-dealer who lives in the fast lane of life, drinks heavily, and has even been arrested once for distributing cocaine and heroin to his cronies in the back room of his club. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661022" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661022">Additional Cases: Case 1</a> <div class="sri-content"> <div class="bookTextSummary"> Your 92-year-old great uncle, BC, was just diagnosed with early stages of Alzheimer’s disease. Yesterday, you started him on donepezil (Aricept, 1) as prescribed by the gerontologist. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660981" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660981">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> JG is a 48-year-old, itinerant farm worker. Ten years ago he was diagnosed with Type 2 DM and until recently, his blood glucose has been controlled with the rarely prescribed, acetohexamide (Compound 1). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661000" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661000">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> OP is a 72-year-old, white female who is recovering from a hip fracture sustained during a square dance lesson at the assisted-living facility where you are the consultant pharmacist. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660957" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660957">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> BK is a 25-year-old white female who is trying to make it in the world of stand-up comedy. She's been playing comedy clubs up and down the East Coast for a couple of years and has found the crowds to be somewhat ruthless when they think she's not sufficiently funny. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660976" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660976">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> HL is a 55-year-old plumber who has been diagnosed with advanced intermediate-grade non-Hodgkin lymphoma. He had recently recovered from a prolonged and severe viral infection, which may have been a factor in the development of this neoplastic disease. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660978" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660978">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> HT, a white, 59-year-old male was diagnosed with idiopathic Parkinsonism 6 months ago. He complains to you that his medicine (Laradopa; L-dopa, Compound 1) no longer controls the tremor in his left hand. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660986" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660986">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> KG is a 5-year-old boy who was recently diagnosed with juvenile arthritis. His physician placed him on tolmetin sodium (15 mg/kg/day in three divided doses) 4 weeks ago, which he is tolerating well, and is now planning to add a disease-modifying antirheumatic agent to the regimen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660997" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660997">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> Ms. PU comes to the prescription counter and asks to speak to the pharmacist. She is carrying her 2-year-old son in her arms and appears to be mildly distressed. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661005" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661005">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> RK is a 26-year-old female who works at a popular roadside restaurant in Kualapuu, Molokai (Hawaii). She spent her childhood and young adulthood in the Kalaupapa leper colony located on the island with her father, who was a missionary in service of the Methodist church. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661009" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661009">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> ST is a 36-year-old female with a history of depression. ST’s life has never been stable (she even spent a few years on the streets), but she has been living with her brother and his family for the past three years. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661016" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661016">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> YH, a 29 yo white prostitute who works the downtown district, visits the free clinic where you volunteer time. YH is new to town and very nervous about coming to the clinic, as she does not yet know whom she can trust. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661025" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661025">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> ZF, a 57-year-old, semi-retired male librarian, has been suffering with recurrent herpes simplex keratitis in his left eye for several years. Until recently, the epithelial eruptions have been controlled by topical application of vidarabine into the lower conjunctival sac 5 times/day at 3-hour intervals. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660949" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660949">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> A young male patient, BO, will undergo surgery to repair torn ligaments in his left knee. The knee injury was the result of a rough game of intramural “touch football” as part of the fraternity competition at his university. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660951" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660951">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> AF is a 64-year-old retired schoolteacher who has been battling debilitating rheumatoid arthritis (RA) for several years. Unfortunately, she has been nonresponsive to several different nonsteroidal anti-inflammatory drug s (NSAIDs), including the cyclooxygenase 2 (COX-2) selective ones. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660958" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660958">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> BK is a 29-year-old, female weight lifter who is in training for a regional competition that will take place in 4 months. A patient at your full-service pharmacy for several years, she is healthy and usually is in only to stock up on herbal products, vitamins, nutritional supplements, and to get her Rx oral contraceptives (Demulen which contains 35 µg ethinyl estradiol and 1 mg ethynodiol diacetate). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660963" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660963">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> DL is a 43-year-old recovering drug addict who, until recently, was living on the streets of New York. He came from a loving and religious home, however, and responded to the call of a socially conscious church coalition to enter rehabilitation. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660972" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660972">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> GK is a 32-year-old Japanese-American mother of three children under the age of 7. She holds down a part-time job as a filing clerk at a busy law office but is always home to meet her children after school. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660973" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660973">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> GM is a 38-year-old mildly obese black, diabetic male who is the CEO of a new and rapidly growing internet-based marketing firm. His hyperglycemia is being controlled moderately well with glipizide, although he has experienced a few hyperglycemic episodes over the past year. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660980" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660980">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> JB, the notorious high-living nightclub owner from the Case Study 1, has recovered from his heroin overdose, thanks to your sound application of opioid SAR to rescue him from himself. Unfortunately, he has not followed your advice and has continued to drink and abuse heroin. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660984" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660984">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> JR, a 7-year-old Hispanic boy with a history of two episodes of bronchiolitis as an infant, is having trouble keeping up with his playmates at the playground at school. His teachers say he tires easily and seems to run out of breath much sooner than his friends. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660991" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660991">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> LR is a 33 years old Wall Street stockbroker who works the floor from the moment the market opens until it closes. When not shouting and jockeying with his fellow brokers, LR puts in time in his Manhattan office, studying financial projections for stocks and talking to his firm's analysts. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660992" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660992">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> LV, a 65-year-old male, ingested what was described as a large quantity of d-CON Mouse Prufe II rodenticide (0.005% brodifacoum) in a suicidal gesture. He told his wife of the ingestion 6 hr later, and she immediately called 911. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661003" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661003">Additional Cases: Case 2</a> <div class="sri-content"> <div class="bookTextSummary"> PJ, a drug abuser, arrives at the emergency room where you are doing your rotation. He is complaining of chest pains, light headedness, and a sense of panic and he demonstrates profuse sweating. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660969" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660969">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> GB is a 75-year-old male, who sustained a severe hip injury while bone-fish fishing off the Florida Keys. He is presently in the hospital where you are the chief pharmacist and will be undergoing hip repair surgery requiring general anesthesia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661012" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661012">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> Two days ago HW, a 64-year-old white male postal worker, was brought unconscious to the emergency room (ER) of the hospital where you work. His wife told the ER physician that they were spending their usual Wednesday night at home watching Law & Order on television when HW, who had been complaining of a bad headache and stiff neck ever since he got home, suddenly passed out. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661019" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661019">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> You are one of the lucky few students to draw the police forensic laboratory as one of your elective rotations. On your second day there, you get into a discussion about “designer drugs” with one of the analytical chemists. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660964" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660964">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> Dr. B. B. Orbius calls your pharmacy and requests your help in choosing a cholinesterase inhibitor. His patient, KR, is an 80-year-old handicapped female residing in an assisted-living facility. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660971" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660971">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> GG shows up at the diabetes clinic where you work. She is a 68-year-old Native American and her patient profile indicates that she has had Type 2 DM since the age of 45. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660979" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660979">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> JB has recovered from the injuries sustained in his car accident and is about to enter a court-ordered rehabilitation program. He is willing to try recovery but fearful of relapse because his addiction is of long standing and he doesn't quite know how he'll function without access to heroin. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660983" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660983">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> JM is a 56-year-old hairdresser who suffers from rheumatoid arthritis (RA). Early in the course of her disease, her symptoms were well controlled with aspirin; but lately she has been experiencing salicylate-resistant stiffness, swelling, and pain. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661013" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661013">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> VL, a 52-year-old, black, female TV news anchorwoman has developed early signs of Parkinsonism. They include infrequent blinking, poverty of movement, a slight shuffling gait but most disturbing for her career are her loss of voice volume and diminished facial expression. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660975" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660975">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> HB is a hypertensive female music professor who plays first oboe in the “Town & Gown” orchestra at her university. A smoker for 39 of her 53 years, she is starting to have trouble with breath control when playing, and finds herself increasingly out of breath when climbing stairs or engaging in strenuous physical activity. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660985" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660985">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> KB is a 71-year-old patriarch of a family that farms in central Iowa. He was recently diagnosed with carcinoma in situ (CIS) of the bladder, and his physician has placed him on the cisplatin, methotrexate, vincristine (CMV) regimen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660989" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660989">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> KT is a 31-year-old nurse who works in the pediatric intensive care unit of the hospital where you are chief pharmacist. The nursing staff is extremely short handed; and despite recovering from a rather bad cold, KT has been working double shifts to care for the heavy patient load. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660996" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660996">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> Mrs. VG, an octogenarian widow who frequents the pharmacy where you intern, tells you that some of her neighbors have got the grippe, and she's starting to feel a little achy herself. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661008" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661008">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> SN is a 23-year-old female who is in her dermatologist's office to have four rather deep plantar warts removed from the heel of her right foot. The procedure is painful, and the area must be numbed by an injection of a local anesthetic before wart removal can begin. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661011" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661011">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> TLH is a 35-year-old, full-blooded, female member of the Navajo tribe. An artisan, she lives and works outside of Taos, New Mexico, and spends her days making and selling jewelry in a silver and turquoise shop. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661023" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661023">Additional Cases: Case 3</a> <div class="sri-content"> <div class="bookTextSummary"> Your neighbor, a physician who regularly contributes his time and expertise to the humanitarian medical group Doctors Without Borders is having dinner at your home. He is telling about his experience treating patients affected by the civil conflict in Iraq and challenges you to solve a therapeutic problem he had faced. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660962" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660962">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> CW is a 38 year old hot-head who's currently doing a 7–10 year stretch at the Texas State Penitentiary for viciously assaulting his brother-in-law with a frozen tuna after an oil field development deal turned sour. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660993" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660993">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> MD is a 45-year-old white female who will be undergoing a lumpectomy to remove a malignancy in her right breast. MD has a history of reconstructive knee surgeries, which have left her with one kidney as a result of the large doses of cephalosporins she was administered to control postoperative infections. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661007" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661007">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> RP is a 45 yo Caucasian male whose increasingly impulsive, agitated and antisocial behaviors have culminated in a diagnosis of schizophrenia. This is a particularly difficult situation given that, for the past several years, he has been exhibiting symptoms of Parkinson’s Disease, with gait and balance being his most adversely affected abilities. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660952" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660952">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> BB is a 58 yo divorced woman who owns her own travel agency. She has a family history of alcoholism and that coupled with the social nature and constant pressures of her job led BB to become an alcoholic. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661002" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661002">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> PB, the 36-year-old wife of recovering heroin addict JB, is about to deliver their baby. This will be their first child because PB and JB have had trouble conceiving and PB suffered two early miscarriages during previous pregnancies. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661017" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661017">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> You are a 25-year-old, 2nd-year pharmacy student working two jobs trying to put yourself through school. Last weekend you strained a muscle in your lower back unloading a truck of stock for the pharmacy at which you work as an intern. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660961" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660961">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> CB is a 57 yo female independent real estate agent with mild persistent asthma who has recently moved to your community after a traumatic break-up of her 25 year marriage and the death of her beloved mother. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660977" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660977">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> HP is a 23-year-old woman who works as a toll taker at the Bay Bridge tunnel. She complains of constant thirst, frequent urination, and the loss of almost 30 lb in the last month in spite of her continued good appetite. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661006" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661006">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> RO, a 24-year-old accountant, has joined his neighborhood gym to enhance his fitness level and lower his stress. His routine is to swim 30 laps; then take an aerobics class; and if a partner is available, play a little fast-action racquetball. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661020" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661020">Additional Cases: Case 4</a> <div class="sri-content"> <div class="bookTextSummary"> You are working the late shift on Saturday night at your local supermarket pharmacy. JG, the pharmacology lab technician from your school, asks you about the relative merits of OTC eye drops for his congested and red eyes. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661026" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661026">Answers to Additional Cases: Case 1</a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661028" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661028">Answers to Additional Cases: Case 1</a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661027" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661027">Answers to Additional Cases: Case 1</a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661050" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661050">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661064" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661064">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661069" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661069">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661095" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661095">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661114" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661114">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661036" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661036">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661051" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661051">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661055" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661055">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661059" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661059">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661061" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661061">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661073" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661073">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661083" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661083">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661099" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661099">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661107" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661107">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661112" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661112">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661116" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661116">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661032" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661032">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661041" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661041">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661044" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661044">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661048" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661048">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661065" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661065">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661068" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661068">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661075" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661075">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661077" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661077">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661079" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661079">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661086" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661086">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661089" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661089">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661091" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661091">Answers to Additional Cases: Case 1 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661029" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661029">Answers to Additional Cases: Case 2</a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661045" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661045">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661033" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661033">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661042" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661042">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661052" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661052">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661062" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661062">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661066" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661066">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661070" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661070">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661074" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661074">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661078" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661078">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661080" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661080">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661090" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661090">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661092" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661092">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661100" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661100">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661108" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661108">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661037" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661037">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661056" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661056">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661060" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661060">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661084" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661084">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661087" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661087">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661096" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661096">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661117" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661117">Answers to Additional Cases: Case 2 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661030" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661030">Answers to Additional Cases: Case 3</a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661038" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661038">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661057" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661057">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661043" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661043">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661071" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661071">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661081" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661081">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661093" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661093">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661097" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661097">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661109" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661109">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661034" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661034">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661046" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661046">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661053" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661053">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661063" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661063">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661067" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661067">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661101" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661101">Answers to Additional Cases: Case 3 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661035" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661035">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661040" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661040">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661047" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661047">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661054" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661054">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661039" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661039">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661058" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661058">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661072" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661072">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661094" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661094">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="9"> <i class="icon-file-word multimedia-icon"></i> <a class="multimedia-title" data-contentid="6661098" target="_blank" href="/ancillarycontent.ashx?multimediaid=6661098">Answers to Additional Cases: Case 4 </a> <div class="sri-content"> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2728">Foye’s Principles of Medicinal Chemistry, 8e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <a id=C class="letter-jumplink"></a> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659925" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659925">Case 1: Choosing among therapeutic options for breast cancer</a> <div class="sri-content"> <div class="bookTextSummary"> An asymptomatic 52-year-old computer programmer is diagnosed with stage T1 localized breast cancer. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659926" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659926">Case 10: Stroke and aspiration pneumonia</a> <div class="sri-content"> <div class="bookTextSummary"> Mr. S, a 74-year-old retired gas station owner with Alzheimer disease and coronary artery disease, is admitted with a stroke. An ECG also shows an acute myocardial infarction with many premature ventricular contractions. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659927" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659927">Case 11: Stroke and aspiration pneumonia</a> <div class="sri-content"> <div class="bookTextSummary"> Assume the same medical facts as in Case 10, but Mr. S has made no statements about his preferences for care. His wife and daughter believe that he would not want to receive continued intensive care after failing to improve from his stroke. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659928" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659928">Case 12: Stroke and aspiration pneumonia</a> <div class="sri-content"> <div class="bookTextSummary"> Assume the same medical facts as in Case 10, but Mr. S has made no statements about his preferences for care and has no family members. He has lived in a nursing home for several years and has no friends who visit him regularly. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659929" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659929">Case 13: Withdrawal of mechanical ventilation</a> <div class="sri-content"> <div class="bookTextSummary"> Assume that Mrs. O, the 64-year-old retired grocery store owner with end-stage interstitial lung disease from Case 9, was intubated in the ED. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659930" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659930">Case 14: Withdrawal of antibiotics and withholding tube feedings </a> <div class="sri-content"> <div class="bookTextSummary"> Assume that Mrs. O, the 64-year-old retired grocery store owner with end-stage interstitial lung disease from Case 9, is transferred out of the ICU with DNAR and DNI orders, based on the family reports of her previous statements. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659931" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659931">Case 15: Do Not Attempt Resuscitation orders during endoscopy</a> <div class="sri-content"> <div class="bookTextSummary"> A 58-year-old woman with dysphagia is found to have inoperable carcinoma of the esophagus. She realizes her poor prognosis and opts for palliation. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659932" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659932">Case 16: Pneumonia and Alzheimer disease</a> <div class="sri-content"> <div class="bookTextSummary"> A 74-year-old man with severe Alzheimer disease is transferred from a nursing home for treatment for pneumonia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659933" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659933">Case 17: Multiorgan failure</a> <div class="sri-content"> <div class="bookTextSummary"> Mr. D is a 72-year-old homebound man with multisystem failure admitted to a community hospital for pneumonia, a myeloproliferative disorder, and failure to thrive. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659934" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659934">Case 18: Head and neck cancer</a> <div class="sri-content"> <div class="bookTextSummary"> Mrs. M is 57-year-old machinist who has recurrent head and neck cancer that has progressed despite radiation and chemotherapy. She cannot swallow foods and secretions and has to sit upright at night to spit out her secretions </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659935" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659935">Case 19: Failed suicide attempt</a> <div class="sri-content"> <div class="bookTextSummary"> Mrs. M, the patient with head and neck cancer in Case 18, is found at home by her husband after a suicide attempt. She has ingested a combination of tricyclic antidepressants, barbiturates, and alcohol and has left a long explanatory note. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659936" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659936">Case 2: Refusal of treatment by a patient with inoperable cancer</a> <div class="sri-content"> <div class="bookTextSummary"> A 64-year-old man has inoperable pancreatic cancer and obstructive jaundice. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659937" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659937">Case 20: Withdrawal of mechanical ventilation</a> <div class="sri-content"> <div class="bookTextSummary"> Mrs. O, the 64-year-old retired grocery store owner with end-stage interstitial lung disease from Case 9, has mechanical ventilation withdrawn based on evidence that she would not want such treatment. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659938" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659938">Case 21: Caring for a patient with acquired immunodeficiency syndrome</a> <div class="sri-content"> <div class="bookTextSummary"> A 34-year-old unemployed homeless man with acquired immunodeficiency syndrome (AIDS) (CD4 level 47) is admitted to your service with Pneumocystis carinii pneumonia. His IV has infiltrated, and you are asked to restart it. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659939" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659939">Case 22: Outcomes of coronary artery bypass and graft</a> <div class="sri-content"> <div class="bookTextSummary"> Suppose your favorite uncle has been recommended to have coronary artery bypass and graft (CABAG) by his primary care physician and cardiologist in New York. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659940" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659940">Case 23: Carrying out an invasive procedure</a> <div class="sri-content"> <div class="bookTextSummary"> Recall the first time you did a lumbar puncture (LP) (or central line, major suturing, or other major procedure). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659941" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659941">Case 24: Unethical behavior of an attending physician</a> <div class="sri-content"> <div class="bookTextSummary"> On a clerkship you observe what you consider unethical behavior by one of your attending physicians. On several occasions, his speech is slurred and you smell alcohol on his breath. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659942" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659942">Case 25: Muscle weakness due to inadequate potassium replacement</a> <div class="sri-content"> <div class="bookTextSummary"> A 42-year-old man is admitted to you with diabetic ketoacidosis. After treatment with intravenous fluids and an insulin drip, the patient’s glucose declines from 745 to 289 mg per dl after 4 hours. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659943" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659943">Case 26: Treating adolescents without parental consent</a> <div class="sri-content"> <div class="bookTextSummary"> A 15-year-old high-school student comes to the physician because of dysuria and a discharge from his penis after intercourse without a condom. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659944" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659944">Case 27: Treating children despite refusals</a> <div class="sri-content"> <div class="bookTextSummary"> A 10-year-old boy is taken to the ED with vomiting and right lower quadrant abdominal pain and is found to have appendicitis. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659945" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659945">Case 3: Refusal of blood transfusions by a Jehovah’s Witness </a> <div class="sri-content"> <div class="bookTextSummary"> A 34-year-old grade school teacher is hospitalized after an automobile accident that ruptures his spleen. A devout Jehovah’s Witness, he refuses transfusion. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659946" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659946">Case 4: No clear reason for refusal of medically effective treatment</a> <div class="sri-content"> <div class="bookTextSummary"> A 45-year-old sales clerk has a 1/2-cm breast mass that is found to be malignant on needle aspiration. With either mastectomy or lumpectomy plus radiation, she has an excellent chance of being cured of her cancer. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659947" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659947">Case 5: Reporting a patient with syncope to the Department of Motor Vehicles</a> <div class="sri-content"> <div class="bookTextSummary"> A 76-year-old retired teacher with a history of coronary artery disease is hospitalized after a syncopal episode. He is found to have ventricular tachycardia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659948" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659948">Case 6: Use of anabolic steroids by an athlete </a> <div class="sri-content"> <div class="bookTextSummary"> A colleague asks your advice on a difficult case. A 19-year-old college swimmer reveals that she has started to take anabolic steroids, which she obtains through friends at the gym where she lifts weights. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659949" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659949">Case 7: Disclosure of genetic illness to relatives</a> <div class="sri-content"> <div class="bookTextSummary"> A 40-year-old auto mechanic is found to have a localized breast cancer, which is treated with lumpectomy and radiation. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659950" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659950">Case 8: Refusal of colonoscopy </a> <div class="sri-content"> <div class="bookTextSummary"> A 72-year-old retired lawyer comes into the hospital with lower abdominal pain. He is found to have guaiac positive stools and anemia. You plan to do a colonoscopy, but the patient refuses. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6659951" target="_blank" href="/ancillarycontent.ashx?multimediaid=6659951">Case 9: Mechanical ventilation in end-stage lung disease</a> <div class="sri-content"> <div class="bookTextSummary"> Mrs. O, a 64-year-old retired grocery store owner with end-stage interstitial lung disease, presents to the emergency department for shortness of breath that began several days ago. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2606">Resolving Ethical Dilemmas: A Guide for Clinicians, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660434" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660434">Case Study 10.1</a> <div class="sri-content"> <div class="bookTextSummary"> Theophylline has an average clearance of 2.8 L/hr and volume of distribution of 35 L. The therapeutic window is known to be between 10 mg/L and 20 mg/L. Theophylline can be administered as a constant rate infusion. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660435" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660435">Case Study 11.1</a> <div class="sri-content"> <div class="bookTextSummary"> A drug (400 mg) is given as a multiple-dose oral treatment. The drug is completely absorbed. The clearance is 20 L/hr and the volume of distribution is 50 L. The absorption rate constant is 2.5 hr-1. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660436" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660436">Case Study 12.1</a> <div class="sri-content"> <div class="bookTextSummary"> Compare the following two pharmacokinetic profiles: Case A: A hepatically cleared high-extraction drug (400 mg) is given as an oral tablet. The absorption is very rapid and approximates a bolus input. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660437" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660437">Case Study 16.1</a> <div class="sri-content"> <div class="bookTextSummary"> Phenytoin is a drug with nonlinear pharmacokinetics which can be described using Michaelis-Mentin kinetics. Assume the following pharmacokinetic parameters for phenytoin after oral administration: V = 45 L, Km = 4 mg/L, Vm = 20 mg/hr, ka = 1 hr-1, F = 1 </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660438" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660438">Case Study 19.1</a> <div class="sri-content"> <div class="bookTextSummary"> A drug that follows a two-compartment model has the following pharmacokinetic microconstants: k10 = 0.5 hr-1, k12 = 1 hr-1, k21 = 2 hr-1, V1 = 25 L. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660439" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660439">Case Study 19.2</a> <div class="sri-content"> <div class="bookTextSummary"> Compare the pharmacokinetic profiles of two drugs after intravenous bolus injection and after constant rate infusion. Both drugs have a clearance of 20 L/hr, and volumes of distribution of V1 = 50 L and V2 = 100 L. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660440" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660440">Case Study 19.3</a> <div class="sri-content"> <div class="bookTextSummary"> A drug that follows a two-compartment model (CL = 80 L/hr, V1 = 50 L, V2 = 200 L, k21 = 0.6 hr-1) is given orally at a dose of 400 mg in to different dosage forms. Tablet A has a rapid drug release and absorption (ka = 3 hr-1). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660441" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660441">Case Study 2.1</a> <div class="sri-content"> <div class="bookTextSummary"> (1) Compare the concentration-effect relationships for two drugs with Hill factors of ?=1 and C50 values of 10 and 100 mg/L. (2) Compare the concentration-effect relationship for two drugs with the same C50 value (10 mg/L) and Hill factors of ?=1 and ?=2. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660442" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660442">Case Study 3.1</a> <div class="sri-content"> <div class="bookTextSummary"> A drug (400 mg) is given as an intravenous bolus. The clearance is 10 L/hr and the volume of distribution is 50 L. Assume a one-compartment body model. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660443" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660443">Case Study 4.1</a> <div class="sri-content"> <div class="bookTextSummary"> A hepatically eliminated drug (400 mg) is given as an intravenous bolus. The intrinsic clearance (CLint) is 200 L/hr. Liver blood flow is 90 L/hr, and plasma and tissue water volumes are 3 L and 39 L, respectively. Both plasma protein binding and tissue binding are 90%. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660444" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660444">Case Study 5.1</a> <div class="sri-content"> <div class="bookTextSummary"> A hepatically cleared high-extraction drug (800 mg) is given as an intravenous bolus. The intrinsic clearance is 4000 L/hr and the protein binding in plasma and tissues is 80%. Assume blood and tissue water volumes of 5 and 39 L and a liver blood flow of 90 L/hr. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660445" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660445">Case Study 6.1</a> <div class="sri-content"> <div class="bookTextSummary"> A drug (400 mg) is given as an oral tablet. The drug is completely absorbed. The clearance is 15 L/hr and the volume of distribution is 40 L. The absorption rate constant is 2.5 hr-1. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660446" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660446">Case Study 7.1</a> <div class="sri-content"> <div class="bookTextSummary"> A hepatically cleared high-extraction drug (400 mg) is given as an oral tablet. The absorption is very rapid and approximates a bolus input. The intrinsic clearance is 5000 L/hr and the plasma protein and tissue binding are 80% and 98%, respectively. Assume blood and tissue water volumes of 5 and 39 L and a liver blood flow of 90 L/hr. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660447" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660447">Case Study 8.1</a> <div class="sri-content"> <div class="bookTextSummary"> A drug with CL = 20 L/hr and V = 50 L is given orally to two different patients A and B. The dose of 400 mg is completely absorbed, however A takes the tablet with a meal (ka = 0.1 hr-1) whereas B takes it on an empty stomach (ka = 0.5 hr-1). Furthermore, A is more sensitive to the drug (C50 of 5 mg/L vs. 10 mg/L for B). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660448" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660448">Case Study 9.1</a> <div class="sri-content"> <div class="bookTextSummary"> Theophylline has an average clearance of 2.8 L/hr and volume of distribution of 35 L. The therapeutic window is known to be between 10 mg/L and 20 mg/L. Immediate release oral theophylline products have a rapid absorption (ka = 3 hr-1). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=2695">Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 5e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <a id=P class="letter-jumplink"></a> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660535" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660535">Part I: Cellular Physiology Cases Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A 16-year-old boy arrives in a Texas hospital emergency room in a semiconscious state. He was transported there after collapsing during football practice. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660538" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660538">Part II: Neuromuscular Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A previously healthy 30-year-old man notices difficulty completing his usual exercise routine over the last 2 weeks because of excessive fatigue during the workout. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660533" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660533">Part III: Blood and Immunology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> An 18-month-old boy, with a high fever and cough and with a history of frequent infections, is brought to the emergency department by his father. A blood examination shows elevated numbers of neutrophils but no other defects. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660534" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660534">Part IV: Cardiovascular Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A 15-year-old girl sees her family physician for a routine school athletic physical. Upon routine examination, her physician detects a reasonably loud systolic murmur when placing her stethoscope parasternally around the second and third intercostal spaces, but her physical exam is otherwise unremarkable. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660536" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660536">Part IX: Endocrine Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> An 8-year-old girl was diagnosed with type 1 diabetes. Nausea and vomiting, symptoms of ketoacidosis, which is not uncommon, were accompanied by polyuria, polydipsia, polyphagia, weight loss, and blurred vision. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660541" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660541">Part V: Respiratory Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> Recovering from a heart attack and fighting pneumonia, a 65-year-old Vietnam veteran was transferred from the VA hospital to the university hospital to be evaluated for surgery to repair his blocked arteries. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660539" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660539">Part VI: Renal Physiology and Body Fluids Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A 6-year-old boy is brought to the pediatrician by his mother because of a puffy face and lethargy. A few weeks before, he had an upper respiratory tract infection, probably caused by a virus. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660537" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660537">Part VII: Gastrointestinal Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A previously healthy girl presented at age 10 years with anorexia, abdominal distention, abdominal pain, vomiting, and severe constipation that failed to respond to large doses of laxatives. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660542" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660542">Part VIII: Temperature Regulation and Exercise Physiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> It was mid-August in San Antonio, another week of consecutive greater than 90°F days with high humidity. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660540" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660540">Part X: Reproductive Phsyiology Case Studies</a> <div class="sri-content"> <div class="bookTextSummary"> A 20-year-old male patient presented with lack of sexual development. On examination, he was eunuchoidal and hypogonadal, and olfactory function testing showed he was anosmic. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3211">Medical Physiology: Principles for Clinical Medicine, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660893" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660893">Patient Profiles: Al Martini History</a> <div class="sri-content"> <div class="bookTextSummary"> Al Martini, a 44-year-old male who has been an alcoholic for the past 5 years, has a markedly diminished appetite for food. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660894" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660894">Patient Profiles: Amanda Tin History</a> <div class="sri-content"> <div class="bookTextSummary"> Amanda Tin (amanitin) picked mushrooms in a wooded area near her home. A few hours after eating one small mushroom, she experienced mild nausea and diarrhea. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660895" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660895">Patient Profiles: Amy Biasis Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Amy Biasis (“amoebiasis”), a 23-year-old missionary, was brought to the hospital emergency room complaining of the abrupt onset of fever, chills, and severe pain in the right upper quadrant of her abdomen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660896" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660896">Patient Profiles: Amy Lloyd History</a> <div class="sri-content"> <div class="bookTextSummary"> Amy Lloyd (“amyloid”) is a 62-year-old woman who presents with weakness, fatigue, an enlarged tongue (macroglossia), and edema. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660897" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660897">Patient Profiles: Ann Jeina History</a> <div class="sri-content"> <div class="bookTextSummary"> Anne Jeina is a 54-year-old woman who arrived in the hospital 4 days ago, approximately 5 hours after she began to feel chest pain. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660898" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660898">Patient Profiles: Ann O'Rexia History</a> <div class="sri-content"> <div class="bookTextSummary"> Ann O’Rexia is a 23-year-old buyer for a woman’s clothing store. Despite the fact that she is 5 feet 7 inches tall and weighs 99 lb, she is convinced she is overweight. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660899" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660899">Patient Profiles: Ann Sulin Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Ann Sulin returned to her physician for her monthly office visit. She has been seeing her physician for over a year due to obesity and elevated blood glucose levels. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660900" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660900">Patient Profiles: Anne Niemick History</a> <div class="sri-content"> <div class="bookTextSummary"> Anne Niemick is a 4-year-old girl of Mediterranean ancestry whose height and body weight are below the 20th percentile for girls of her age. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660901" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660901">Patient Profiles: Arlyn Foma History</a> <div class="sri-content"> <div class="bookTextSummary"> Arlyn Foma, a 68-year old male, complained of fatigue, loss of appetite, and a low grade fever. An open biopsy of a lymph node revealed the presence of non-Hodgkin’s lymphoma, follicular type </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660902" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660902">Patient Profiles: Bea Selmass Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Bea Selmass is a 46-year-old woman who 6 months earlier began noting episodes of fatigue and confusion as she finished her daily pre-breakfast jog. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660903" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660903">Patient Profiles: Bea Twelvlow Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Bea Twelvlow, a 75 year old female, went to see her physician due to a numbness and tingling in her arms and legs. A dietary history indicated a normal and healthy diet but Bea was not taking any supplemental vitamin pills. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660904" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660904">Patient Profiles: Cal Kulis History</a> <div class="sri-content"> <div class="bookTextSummary"> Cal Kulis is an 18-year-old male who was brought to the hospital by his mother because of the sudden onset of severe pain in the left flank radiating around his left side toward his pubic area. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660905" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660905">Patient Profiles: Candice Sucher Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Candice Sucher is an 18-year-old female who presented to her physician for a precollege physical examination. While taking her medical history, the doctor learned that she carefully avoided eating all fruits and any foods that contained table sugar. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660906" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660906">Patient Profiles: Carrie Sichel History</a> <div class="sri-content"> <div class="bookTextSummary"> Carrie Sichel, Will Sichel’s 19-year-old sister, is considering marriage. Her growth and development have been normal and she is free of symptoms of sickle cell anemia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660907" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660907">Patient Profiles: Colin Tuma History</a> <div class="sri-content"> <div class="bookTextSummary"> Colin Tuma had two intestinal polyps at age 50, which were removed via a colonoscope. However, he did not return for a five year colonoscopic examination as instructed. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660908" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660908">Patient Profiles: Colleen Lakker Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Colleen Lakker was born 6 weeks prematurely. She appeared normal until about 30 minutes after delivery, when her respirations became rapid at 64 per minute with audible respiratory grunting. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660909" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660909">Patient Profiles: Cora Nari History</a> <div class="sri-content"> <div class="bookTextSummary"> Cora Nari is a 64-year-old woman who had a myocardial infarction (MI, often referred to as a “coronary”) 8 months ago and had a significant loss of functional heart muscle. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660910" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660910">Patient Profiles: Dennis 'the Menace' Veere History</a> <div class="sri-content"> <div class="bookTextSummary"> Dennis “the Menace” Veere, age 3, was brought to the emergency department by his grandfather, Percy Veere. While Dennis was visiting his grandfather, he climbed up on a chair and took a half-full 500-tablet bottle of 325 mg aspirin (acetylsalicylic acid) tablets from the kitchen counter. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660911" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660911">Patient Profiles: Deria Voider Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Deria Voider is a 20-year-old exchange student from Nigeria who has noted gastrointestinal bloating, abdominal cramps, and intermittent diarrhea ever since arriving in the United States 6 months earlier. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660912" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660912">Patient Profiles: Dianne (Di) Abietes History</a> <div class="sri-content"> <div class="bookTextSummary"> Dianne (Di) Abietes is a 26-year-old woman who was diagnosed with type 1 diabetes mellitus at the age of 12. She has an absolute insulin deficiency resulting from autoimmune destruction of the ß-cells of her pancreas. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660913" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660913">Patient Profiles: Emma Wheezer Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Emma Wheezer presented to the emergency room 3 days after discharge from the hospital following a 10-day admission for severe refractory bronchial asthma. She required high dose intravenous methylprednisolone (a synthetic anti-inflammatory glucocorticoid) for the first 8 days of her stay. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660914" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660914">Patient Profiles: Erin Galway Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Erin Galway is a 3-week-old female infant who began vomiting 3 days after birth, usually within 30 minutes after breastfeeding. Her abdomen became distended at these times and she became irritable and cried frequently. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660915" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660915">Patient Profiles: Erna Nemdy History</a> <div class="sri-content"> <div class="bookTextSummary"> Erna Nemdy (“earn an M.D.”), a 25-year-old junior medical student brings her healthy 4-month-old daughter, Beverly, to the pediatrician for her second diphtheria, pertussis, tetanus (DTaP,acellular pertussis) immunization, which she received along with the pneumococcal, inactivated polio, haemophilus influenza and rotavirus vaccines. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660916" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660916">Patient Profiles: Evan Applebod Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Ivan Applebod’s brother, Evan Applebod, was six feet tall and weighed 425 pounds (BMI = 57.6 kg/m2). He had only been successful in losing weight once in his life, in 1977 when he lost 30 lbs through a combination of diet and exercise with the support of a registered dietitian, but quickly regained this weight back. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660917" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660917">Patient Profiles: Getta Carbo Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> A newborn baby girl, Getta Carbo, was born after a 38-week gestation. Her mother, a 36-year-old woman, developed a significant viral infection that resulted in a severe loss of appetite and recurrent vomiting in the month preceding delivery. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660918" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660918">Patient Profiles: Homer Sistine Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Homer Sistine, a 14-year-old male, had a sudden grand mal seizure (with jerking movements of the torso and head) in his eighth grade classroom. The school physician noted mild weakness of the muscles of the left side of Homer’s face and of his left arm and leg. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660919" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660919">Patient Profiles: Ivan Applebod History</a> <div class="sri-content"> <div class="bookTextSummary"> Ivan Applebod is a 56-year-old accountant who has been morbidly obese for a number of years. He exhibits a pattern of central obesity, called an?apple shape, which is caused by excess adipose tissue deposited in the abdominal area. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660920" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660920">Patient Profiles: Ivy Sharer History</a> <div class="sri-content"> <div class="bookTextSummary"> Ivy Sharer is a 26-year-old intravenous (IV) drug user who has shared needles with another addict for several years. Five months before presenting to the emergency department with soaking night sweats, she experienced a 3-week course of a flu-like syndrome with fever, malaise, and muscle aches. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660921" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660921">Patient Profiles: Jay Sakz History</a> <div class="sri-content"> <div class="bookTextSummary"> Jay Sakz is a 9-month-old male infant of Ashkenazi Jewish parentage. His growth and development were normal until age 5 months when he began to exhibit mild, generalized muscle weakness. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660922" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660922">Patient Profiles: Jean Ann Tonich History</a> <div class="sri-content"> <div class="bookTextSummary"> Jean Ann Tonich, a 46-year-old commercial artist, recently lost her job because of absenteeism. Her husband of 24 years had left her 10 months earlier. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660923" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660923">Patient Profiles: Jim Bodie Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Jim Bodie, a 19-year-old body builder, was rushed to the hospital emergency room in a coma. One-half hour earlier, his mother had heard a loud crashing sound in the basement where Jim had been lifting weights and completing his daily workout on the treadmill. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660924" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660924">Patient Profiles: Katie Colamin Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Katie Colamin, a 34-year-old dress designer, developed alarming palpitations of her heart while bending forward to pick up her cat. She also developed a pounding headache and sweated profusely. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660925" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660925">Patient Profiles: Katta Bolic Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Katta Bolic, a 62-year-old homeless woman, was found by a neighborhood child who heard Katta’s moans coming from an abandoned building. The child’s mother called the police, who took Katta to the hospital emergency room. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660926" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660926">Patient Profiles: Les Dopaman History</a> <div class="sri-content"> <div class="bookTextSummary"> Two years ago, Les Dopaman, a 62-year-old male, noted an increasing tremor of his right hand when sitting quietly (resting tremor). The tremor disappeared if he actively used this hand to do purposeful movement. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660927" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660927">Patient Profiles: Lofata Burne History</a> <div class="sri-content"> <div class="bookTextSummary"> Lofata Burne is a 16-year-old female. Since age 14 months she has experienced recurrent episodes of profound fatigue associated with vomiting and increased perspiration, which required hospitalization. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660928" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660928">Patient Profiles: Lopa Fusor History</a> <div class="sri-content"> <div class="bookTextSummary"> Lopa Fusor is a 68-year-old woman who is admitted to the hospital emergency room with very low blood pressure (80/40 mm Hg) caused by an acute hemorrhage from a previously diagnosed ulcer of the stomach. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660929" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660929">Patient Profiles: Lotta Topaigne History</a> <div class="sri-content"> <div class="bookTextSummary"> Lotta Topaigne is a 54 year-old woman who came to the physician’s office complaining of a severe throbbing pain in the right great toe that began 8 hours earlier. The toe has suffered no trauma but appears red and swollen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660930" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660930">Patient Profiles: Mannie Weitzels History</a> <div class="sri-content"> <div class="bookTextSummary"> Mannie Weitzels is a 56-year-old male who complains of headaches, weight loss related to a declining appetite for food, and a decreasing tolerance for exercise. He notes discomfort and fullness in the left upper quadrant of his abdomen. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660931" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660931">Patient Profiles: Mel Anoma History</a> <div class="sri-content"> <div class="bookTextSummary"> Melvin (Mel) Anoma is a 46-year old male who noted a superficial, brownish-black, 5-mm nodule with irregular borders in the skin on his chest. He was scheduled for outpatient surgery, at which time a wide excision biopsy was performed (in an excision biopsy the complete mole is removed and biopsied). </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660932" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660932">Patient Profiles: Mya Sthenia History</a> <div class="sri-content"> <div class="bookTextSummary"> Mya Sthenia is a 37 year-old female who complains of increasing muscle fatigue in her lower extremities with walking. If she rests for five to ten minutes, her leg strength returns to normal. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660933" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660933">Patient Profiles: Newman Itis History</a> <div class="sri-content"> <div class="bookTextSummary"> Newman Itis complains to his physician of a fever and cough. His cough is productive of thick yellow-brown sputum. He is empirically started on azithromycin for community acquired pneumonia. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660934" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660934">Patient Profiles: Nick O'Tyne History</a> <div class="sri-content"> <div class="bookTextSummary"> Nick O’Tyne is a 62-year-old electrician who has smoked two packs of cigarettes a day for 40 years. He recently noted that his chronic cough had gotten worse. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660935" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660935">Patient Profiles: Nona Melos Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Nona Melos is a 7-month-old baby girl, the second child born to unrelated parents. Her mother had a healthy, full-term pregnancy, and Nona’s birth weight was normal. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660936" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660936">Patient Profiles: Otto Shape History</a> <div class="sri-content"> <div class="bookTextSummary"> Otto Shape is a 25-year-old medical student who was very athletic during high school and college, and is now “out-of-shape”. Since he started medical school, he has been gaining weight. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660937" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660937">Patient Profiles: Percy Veere History</a> <div class="sri-content"> <div class="bookTextSummary"> Percy Veere is a 59-year-old schoolteacher who was in good health until his wife died suddenly. Since that time he has experienced an increasing degree of fatigue and has lost interest in many of the activities he previously enjoyed. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660938" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660938">Patient Profiles: Piquet Yuria Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Piquet Yuria, a 4-month-old female infant, emigrated from the Soviet Union with her French mother and Russian father 1 month ago. She was normal at birth but in the last several weeks was less than normally attentive to her surroundings. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660939" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660939">Patient Profiles: Rena Felya Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Rena Felya, a 9-year-old girl, complained of a severe pain in her throat and difficulty in swallowing. She had chills, sweats, headache, and a fever of 102.4° F. J1255 </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660940" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660940">Patient Profiles: Sam Atotrope Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Sam Atotrope, a 42-year-old jeweler, noted increasingly severe headaches behind his eyes sometimes associated with a “flash of light” in his visual fields. At times his vision seemed blurred, making it difficult to perform some of the intricate work required of a jeweler. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660941" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660941">Patient Profiles: Sis Lupus History</a> <div class="sri-content"> <div class="bookTextSummary"> Sis Lupus, a 28-year-old computer programmer, notes increasing fatigue, pleuritic chest pain, and a nonproductive cough. In addition, she complains of joint pains, especially in her hands. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660942" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660942">Patient Profiles: Sissy Fibrosa History</a> <div class="sri-content"> <div class="bookTextSummary"> Sissy Fibrosa is a 3-year-old Caucasian female who has been diagnosed with cystic fibrosis (CF). Cystic fibrosis is a disease caused by an inherited deficiency in the CFTR (cystic fibrosis transmembrane conductance regulator) protein, which is a chloride channel. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660943" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660943">Patient Profiles: Sloe Klotter Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Sloe Klotter, a 6-month-old male infant, was brought to his pediatrician’s office with a painful, expanding mass in his right upper thigh which was first noted just hours after he fell down three uncarpeted steps in his home. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660944" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660944">Patient Profiles: Spiro Site Patient File</a> <div class="sri-content"> <div class="bookTextSummary"> Spiro Site is a 21-year-old college student who complains of feeling tired all the time. Two years previously he had had gallstones removed, which consisted mostly of bilirubin. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660945" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660945">Patient Profiles: Vera Leizd Patient History</a> <div class="sri-content"> <div class="bookTextSummary"> Vera Leizd is a 34-year-old woman in whom pubertal changes began at age 12, leading to the development of normal secondary sexual characteristics and the onset of menses at age 13. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660946" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660946">Patient Profiles: Victoria Tim History</a> <div class="sri-content"> <div class="bookTextSummary"> Victoria Tim was a 21-year-old woman who was the victim of a rape and murder. Her parents told police that she had left her home and drove to the local convenience store. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660947" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660947">Patient Profiles: Will Sichel History</a> <div class="sri-content"> <div class="bookTextSummary"> Will Sichel is a 17-year-old male who presented to the hospital emergency room with severe pain in his lower back, abdomen, and legs, which began after a 2-day history of nausea and vomiting caused by gastroenteritis. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> <li class="js-ancillary-list-item" data-multimedia-type-id="6"> <i class="icon-file-pdf multimedia-icon"></i> <a class="multimedia-title" data-contentid="6660948" target="_blank" href="/ancillarycontent.ashx?multimediaid=6660948">Patient Profiles: X. S. Teefore History</a> <div class="sri-content"> <div class="bookTextSummary"> X.S. Teefore is a 26-year-old male who noted heat intolerance with heavy sweating, heart palpitations, and tremulousness. Over the past 4 months he has lost weight in spite of a good appetite. </div> <div class="related-to"> <span class="related-title">Related to:</span> <a href="/book.aspx?bookid=3220">Marks’ Basic Medical Biochemistry: A Clinical Approach, 6e</a> </div> </div> </li> </ul> </div> </div> </div> </div> </div> </div> </section> </section> <div class="footer-push"></div> </div> <div class="modal-overlay"></div> <section class="sitefooter"> <footer> <div class="footer"> <div class="row"> <div class="large-7 columns footerMenu no-print"> <ul> <li><a href="/public/Privacy.aspx">Disclaimer</a></li> <li><a href="/public/Privacy.aspx">Privacy statement</a></li> <li><a href="/public/Terms_of_Use.aspx">Terms & conditions</a></li> <li><a id="ot-sdk-btn" href="javascript:;" class="ot-sdk-show-settings ot-sdk-hl">Cookie Settings</a></li> </ul> </div> <div class="large-5 columns"> <div class="footerCopyright"> <div class="widget-FooterCopyrightStatement widget-instance-FooterCopyrightStatement_WKHL"> <div class="footer-Copyright-statement"> ©2025 Wolters Kluwer Health, Inc. and/or its subsidiaries. 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document.all["ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail"] : document.getElementById("ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail"); ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.controltovalidate = "ctl00_ctl00_BodyContent_masthead_GlobalSignin_txtEmail"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.focusOnError = "t"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.errormessage = "Required"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.display = "Dynamic"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.evaluationfunction = "RequiredFieldValidatorEvaluateIsValid"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqEmail.initialvalue = ""; var ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword = document.all ? document.all["ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword"] : document.getElementById("ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword"); ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.controltovalidate = "ctl00_ctl00_BodyContent_masthead_GlobalSignin_txtPassword"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.focusOnError = "t"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.errormessage = "Required"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.display = "Dynamic"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.evaluationfunction = "RequiredFieldValidatorEvaluateIsValid"; ctl00_ctl00_BodyContent_masthead_GlobalSignin_reqPassword.initialvalue = ""; var ctl00_ctl00_BodyContent_siteFooter_feedbackForm_FeedbackSignin_reqEmail = document.all ? 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