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multi-columns-row"> <div id="primary" class="content-area col-md-9 col-lg-9 col-xs-12"> <main id="main" class="site-main"> <article id="post-8942" class="ts-no-featured-content themestek-box-blog-classic post-8942 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">20</div> <div class="ts-blog-classic-dbox-month">May</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/05/20/lexarias-newest-dehydratechtm-2-0-formulation-tested-in-study-hyper-a21-2-demonstrates-its-strongest-cbd-absorption-results-ever/">May 20, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/05/20/lexarias-newest-dehydratechtm-2-0-formulation-tested-in-study-hyper-a21-2-demonstrates-its-strongest-cbd-absorption-results-ever/">Lexaria’s Newest DehydraTECH(TM) 2.0 Formulation Tested in Study HYPER-A21-2 Demonstrates Its Strongest CBD Absorption Results Ever</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><strong><i>New formulation delivers up to 2,708% more CBD into bloodstream* </i></strong></li><br /> <li><strong><i>Human clinical hypertension study HYPER-H21-1 also progressing </i></strong></li><br /> </ul><br /> <br /> <p><strong>KELOWNA, BC / May 20, 2021 /</strong> Lexaria Bioscience Corp. (NASDAQ:LEXX) (NASDAQ:LEXXW) (CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, is pleased to announce successful test results of two new "DehydraTECH<sup>™</sup> 2.0" cannabidiol ("CBD") formulations in its second 2021 applied research and development study program, HYPER-A21-2.</p><br /> <br /> <p>"One of our latest DehydraTECH 2.0 formulations gave us the strongest absorption enhancement results we've ever recorded, at 2,708% more CBD into bloodstream during the study period than the representative industry standard MCT control formulation. It was also 174% more effective than the original DehydraTECH 2.0 formulation from 2019," said Chris Bunka, CEO of Lexaria. "This is a 27-fold improvement in CBD delivery compared to the control formulation."</p><br /> <br /> <p>Study HYPER-A21-2 included three additional new DehydraTECH 2.0 formulation variations designed to enhance CBD delivery performance and pharmacokinetic optimization. Two of the three new DehydraTECH 2.0 formulations delivered improved performance when compared to both Lexaria's original DehdyraTECH 1.0 and 2019 DehydraTECH 2.0 concentration-matched formulations, as well as to a medium chain triglyceride ("MCT") oil based control formulation representative of standard industry practices. The final formulation provided useful data but did not deliver enhanced performance compared to the original DehydraTECH 2.0. Summary data is shown below:</p><br /> <br /> <table align="center" style="width:489.05pt;border-collapse:collapse;border:solid windowtext 1.0pt" width="652"><br /> <tbody><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center;margin-bottom:14px"><b>Formulation</b></p><br /> </td><br /> <td style="border:solid windowtext 1.0pt;width:85.05pt;border-left:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center;margin-bottom:14px"><b>AUClast <sup>(1)</sup> </b><b>(hr kg ng /mL/mg)</b></p><br /> </td><br /> <td style="border:solid windowtext 1.0pt;width:106.3pt;border-left:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center"><b>% Improvement over MCT Formulation</b></p><br /> <br /> <p align="center" style="text-align:center"><b>(p value)</b></p><br /> </td><br /> <td style="border:solid windowtext 1.0pt;width:106.35pt;border-left:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center"><b>% Improvement over original DehydraTECH 1.0 </b></p><br /> <br /> <p align="center" style="text-align:center"><b>(p value)</b></p><br /> </td><br /> <td style="border:solid windowtext 1.0pt;width:99.2pt;border-left:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center"><b>% Improvement over original DehydraTECH 2.0 </b></p><br /> <br /> <p align="center" style="text-align:center"><b>(p value)</b></p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;border-top:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center">MCT Control <sup>(2)</sup></p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:85.05pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center">13.17 ± 6.78</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.3pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.35pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:99.2pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;border-top:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center">Original <sup>(2) </sup>DehydraTECH 1.0</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:85.05pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center">64.6 ± 23.7</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.3pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">390%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.00002)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.35pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:99.2pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;border-top:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center">Original <sup>(3) </sup>DehydraTECH 2.0</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:85.05pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center">134.7 ± 63.7</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.3pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">923%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.00009)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.35pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">108%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.0036)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:99.2pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center">--</p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;border-top:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center"><b>**NEW**</b> DehydraTECH 2.0 Formulation 5 <sup>(4)</sup></p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:85.05pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center">187 ± 95</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.3pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">1,322%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.0001)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.35pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">190%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.001)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:99.2pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center">39%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.08)</p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border:solid windowtext 1.0pt;width:92.15pt;border-top:none;padding:0in 5.4pt 0in 5.4pt" valign="top" width="123"><br /> <p align="center" style="text-align:center"><b>**NEW**</b> DehydraTECH 2.0 Formulation 6 <sup>(4)</sup></p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:85.05pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="113"><br /> <p align="center" style="text-align:center">370 ± 172</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.3pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">2,708%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.00005)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:106.35pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="142"><br /> <p align="center" style="text-align:center">472%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.0001)</p><br /> </td><br /> <td style="border-bottom:solid windowtext 1.0pt;width:99.2pt;border-top:none;border-left:none;border-right:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt" valign="top" width="132"><br /> <p align="center" style="text-align:center">174%</p><br /> <br /> <p align="center" style="text-align:center">(p=0.0008)</p><br /> </td><br /> </tr><br /> </tbody><br /> </table><br /> <br /> <ol><br /> <li>AUC: Area Under the Curve, or total CBD delivery into the rodent bloodstream</li><br /> <li>60-minute study duration</li><br /> <li>60-minute study duration evaluated in 2019</li><br /> <li>120-minute study duration evaluated in 2021</li><br /> </ol><br /> <br /> <p>Lexaria continues to build a robust body of evidence demonstrating that its patented DehydraTECH technology can significantly enhance the delivery of lipophilic active ingredients such as CBD across a range of uptake levels, with ultimate applications to wide ranging areas including consumer packaged goods as well as drugs with potential for disease treatment applications.</p><br /> <br /> <p>In each arm of the study, ten male Sprague-Dawley rats were dosed orally at a level of 25 mg/Kg CBD, and over the next 120 minutes multiple measurements were taken to assess delivery into the bloodstream and tissues comparing the DehydraTECH formulations to certain controls. There were a total of 120 animals for the new DehydraTECH 2.0 formulations evaluated in studies HYPER-A21-1 and HYPER-A21-2. Both studies HYPER-A21-1 and HYPER-A21-2 were conducted by an independent, premier animal testing laboratory located in the United States.</p><br /> <br /> <p>Lexaria also confirms that its HYPER-H21-1 human clinical hypertension study is currently underway and dosing is nearly complete, utilizing a formulation most closely resembling the original 2019 DehydraTECH 2.0. Along with a more than a 3-fold increase in dose quantity, these formulation improvements are expected to be more effective than the original DehydraTECH 1.0 formulation used in Lexaria's foundational 2018 human clinical study that nonetheless evidenced significant blood pressure reduction, as published and available at <a href="https://pr.report/Fnd8cW52">PubMed</a>. Lexaria thus expects improved pharmacokinetic performance in its current human clinical study to translate into further improved pharmacodynamic performance. Lexaria will provide details on the outcomes of study HYPER-H21-1 when they become available.</p><br /> <br /> <p>*<i> Compared with control formula utilizing medium chain triglycerides (coconut oil)</i> <i>representative of standard industry practices</i></p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b><br><br /> Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 19 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/kGSEmYQ6">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b><br><br /> This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT: </b><br><br /> <a href="/cdn-cgi/l/email-protection#610813210d04190013080003080e120208040f02044f020e0c"><span class="__cf_email__" data-cfemail="167f64567a736e77647f77747f7965757f737875733875797b">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE:</strong> Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/648283/Lexarias-Newest-DehydraTECHTM-20-Formulation-Tested-in-Study-HYPER-A21-2-Demonstrates-Its-Strongest-CBD-Absorption-Results-Ever'>https://www.accesswire.com/648283/Lexarias-Newest-DehydraTECHTM-20-Formulation-Tested-in-Study-HYPER-A21-2-Demonstrates-Its-Strongest-CBD-Absorption-Results-Ever</a><br><br><img src='https://www.accesswire.com/img.ashx?id=648283' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/05/20/lexarias-newest-dehydratechtm-2-0-formulation-tested-in-study-hyper-a21-2-demonstrates-its-strongest-cbd-absorption-results-ever/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/05/20/lexarias-newest-dehydratechtm-2-0-formulation-tested-in-study-hyper-a21-2-demonstrates-its-strongest-cbd-absorption-results-ever/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8943" class="ts-no-featured-content themestek-box-blog-classic post-8943 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">12</div> <div class="ts-blog-classic-dbox-month">May</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/05/12/lexaria-strengthens-its-international-patent-portfolio-to-19-patents-granted/">May 12, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/05/12/lexaria-strengthens-its-international-patent-portfolio-to-19-patents-granted/">Lexaria Strengthens Its International Patent Portfolio to 19 Patents Granted</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><strong><i>New patent granted in India bolsters worldwide patent coverage, adding to existing patents in the EU, the U.S., and Australia</i></strong></li><br /> </ul><br /> <br /> <p><b>KELOWNA, BC / May 12, 2021</b> / Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, announces further expansion of its intellectual property portfolio with its first-ever patent granted in India.</p><br /> <br /> <p>The patent is titled "Stable ready-to-drink beverage compositions comprising lipophilic active agents" and is of particular importance given the size of the Indian population, which is nearly four times as large as the U.S. population<i>. </i>The patent is valid for 20 years from the patent application date of Dec. 1, 2016.</p><br /> <br /> <p>"This is our 19<sup>th</sup> patent granted worldwide, allowing us to innovate in the ready-to-drink beverage composition category around the world," said Chris Bunka, CEO of Lexaria. "This new patent complements our existing suite of granted patents spanning the EU, the U.S., and Australia, and provides intellectual property protection to both consumer-packaged goods as well as registered drug applications. We believe these are robust growth categories that add to Lexaria's strategic value."</p><br /> <br /> <p>This is the second patent granted from Lexaria's third patent family. Lexaria's patent application suite has grown to a total of 13 patent families. Active ingredients that may be used under this new patent include NSAIDS (e.g., acetylsalicylic acid, ibuprofen, diclofenac, indomethacin, piroxicam), fat-soluble vitamins, and acetaminophen. Active ingredients under the new patent also include nicotine and cannabinoids.</p><br /> <br /> <p>Claims granted cover a wide range of product formats, including non-carbonated beverages, carbonated beverages, colas, root beers, fruit-flavoured beverages, citrus-flavored beverages, fruit juices, fruit-containing beverages, vegetable juices, vegetable-containing beverages, teas, coffees, dairy beverages, protein-containing beverages, shakes, sports drinks, energy drinks, and flavored waters.</p><br /> <br /> <p>Lexaria has patent applications progressing in countries around the world with aggregate populations of approximately 3.7 billion people and will report on further progress as information becomes available.</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b><br><br /> Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1-2 hours to minutes, and mask unwanted tastes. DehydraTECH is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies, including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products, and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 19 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/VZdDcOz5">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b><br><br /> This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the Company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants, or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the U.S. Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure, or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances, or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT: </b><br><br /> <a href="/cdn-cgi/l/email-protection#d8b1aa98b4bda0b9aab1b9bab1b7abbbb1bdb6bbbdf6bbb7b5"><span class="__cf_email__" data-cfemail="046d764468617c65766d65666d6b77676d616a67612a676b69">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE: </strong>Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/646658/Lexaria-Strengthens-Its-International-Patent-Portfolio-to-19-Patents-Granted'>https://www.accesswire.com/646658/Lexaria-Strengthens-Its-International-Patent-Portfolio-to-19-Patents-Granted</a><br><br><img src='https://www.accesswire.com/img.ashx?id=646658' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/05/12/lexaria-strengthens-its-international-patent-portfolio-to-19-patents-granted/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/05/12/lexaria-strengthens-its-international-patent-portfolio-to-19-patents-granted/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8944" class="ts-no-featured-content themestek-box-blog-classic post-8944 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">07</div> <div class="ts-blog-classic-dbox-month">May</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/05/07/lexaria-to-present-at-the-benzinga-global-small-cap-conference-on-may-13-2021-at-350-p-m-et/">May 7, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/05/07/lexaria-to-present-at-the-benzinga-global-small-cap-conference-on-may-13-2021-at-350-p-m-et/">Lexaria to Present at the Benzinga Global Small Cap Conference on May 13, 2021 at 3:50 p.m. ET</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><p><strong><i>Lexaria Recently Announced Favorable Data on Its First Animal Study, As Well as the Commencement of Its First Human Clinical Study, Under Its 2021 Hypertension R&D Program</i></strong></p><br /> <br /> <p><b>KELOWNA, BC / May 7, 2021 / </b>Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW)(CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, today announced that CEO Chris Bunka is presenting at the <a href="https://pr.report/Blsb1jQJ">Benzinga Global Small Cap Conference</a> to be held on May 13-14, 2021. Complimentary investor registration can be accessed through the conference link below.</p><br /> <br /> <p>Presentation date: Thursday, May 13, 2021</p><br /> <br /> <p>Presentation time: 3:50 p.m. ET / 12:50 p.m. PT</p><br /> <br /> <p>Event registration link: <a href="https://pr.report/14B3oHr6">Benzinga Global Small Cap Conference</a></p><br /> <br /> <p>YouTube link: <a href="https://pr.report/bTFv4WEJ">https://www.youtube.com/watch?v=Fy4-KfJWgdE</a></p><br /> <br /> <p>Mr. Bunka will provide an overview of the Company, including its DehydraTECH™ drug delivery technology that improves the way active pharmaceutical ingredients enter the bloodstream. He will also discuss Lexaria's applied R&D programs that are evaluating the delivery effectiveness of DehydraTECH-processed cannabidiol (CBD) for hypertension, antiviral applications for SARS diseases and other infectious diseases, and multiple new markets, as well as provide updates on the progress of these studies.</p><br /> <br /> <p>The Benzinga Global Small Cap Conference, a showcase for small-cap investing, will be held in an entirely virtual setting. Designed to bridge the gap between small-cap companies, investors and traders, the Conference will enable executive leadership of companies to network and communicate with a broad and diverse global investor audience.</p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b></p><br /> <br /> <p>Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/9m0wRSMO">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b></p><br /> <br /> <p>This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT: </b><br><br /> <a href="/cdn-cgi/l/email-protection#fa9388ba969f829b88939b9893958999939f94999fd4999597"><span class="__cf_email__" data-cfemail="deb7ac9eb2bba6bfacb7bfbcb7b1adbdb7bbb0bdbbf0bdb1b3">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE:</strong> Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/645580/Lexaria-to-Present-at-the-Benzinga-Global-Small-Cap-Conference-on-May-13-2021-at-350-pm-ET'>https://www.accesswire.com/645580/Lexaria-to-Present-at-the-Benzinga-Global-Small-Cap-Conference-on-May-13-2021-at-350-pm-ET</a><br><br><img src='https://www.accesswire.com/img.ashx?id=645580' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/05/07/lexaria-to-present-at-the-benzinga-global-small-cap-conference-on-may-13-2021-at-350-p-m-et/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/05/07/lexaria-to-present-at-the-benzinga-global-small-cap-conference-on-may-13-2021-at-350-p-m-et/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author </span> <a class="url fn n" href="https://lexariabioscience.com/author/mmcdonald/"><i class="ts-labtechco-icon-user"></i> mmcdonald</a> </span> </span> </div> </div> </div> </article> <article id="post-8945" class="ts-no-featured-content themestek-box-blog-classic post-8945 post type-post status-publish format-standard hentry category-press-releases" > <div class="ts-blog-classic-featured-wrapper"> <div class="ts-blog-classic-datebox-overlay"> <div class="ts-blog-classic-dbox-date">06</div> <div class="ts-blog-classic-dbox-month">May</div> </div> </div> <div class="ts-blog-classic-box-content ">  <div class="ts-featured-meta-wrapper ts-featured-overlay"> <div class="ts-blog-post-date"> <span class="ts-meta-line"><span class="screen-reader-text ts-hide">Date </span> <i class="ts-labtechco-icon-clock"></i> <a href="https://lexariabioscience.com/2021/05/06/lexaria-issues-successful-results-from-first-2021-study-hyper-a21-1/">May 6, 2021</a></span> </div> <div class="ts-blog-post-cat ts-blog-post-cat-above-title"> <span class="ts-meta-line cat-links"><span class="screen-reader-text ts-hide">Categories </span> <i class="ts-labtechco-icon-category"></i> <a href="https://lexariabioscience.com/category/press-releases/">Press Releases</a></span> </div> <div class="themestek-box-title"><h4><a href="https://lexariabioscience.com/2021/05/06/lexaria-issues-successful-results-from-first-2021-study-hyper-a21-1/">Lexaria Issues Successful Results from First 2021 Study, HYPER-A21-1</a></h4></div> </div>  <div class="entry-content"> <div class="themestek-box-desc-text"><div class="b2iNewsItemBodyDiv"><ul><br /> <li><i>Up to 2,178% more CBD delivered into bloodstream* </i></li><br /> <li><i>Up to 1,737% more CBD delivered into brain tissue*</i></li><br /> </ul><br /> <br /> <p><b>KELOWNA, BC / May 6, 2021 / </b>Lexaria Bioscience Corp. (NASDAQ:LEXX) (NASDAQ:LEXXW) (CSE:LXX) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, is pleased to announce successful outcomes in its first sets of data from its 2021 applied research and development (R&D) study programs.</p><br /> <br /> <p>Study HYPER-A21-1 included three new "DehydraTECH 2.0" formulation variations designed to enable cannabidiol ("CBD") delivery performance enhancements and pharmacokinetic optimization. All three new DehydraTECH 2.0 formulations delivered improved performance when compared to both Lexaria's original DehdyraTECH 1.0 and 2.0 concentration-matched formulations, as well as to a medium chain triglyceride ("MCT") oil based control formulation representative of standard industry practices Summary data is shown below:</p><br /> <br /> <table align="center" style="border-collapse:collapse;border:none" width="650"><br /> <tbody><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:2px solid black;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <p align="center" style="text-align:center;margin-bottom:15px"><b>Formulation</b></p><br /> </td><br /> <td style="border-bottom:2px solid black;width:113px;padding:0cm 7px 0cm 7px;border-top:2px solid black;border-right:2px solid black;border-left:none" valign="top"><br /> <p align="center" style="text-align:center;margin-bottom:15px"><b>AUClast <sup>(1)</sup> </b><b>(hr kg ng /mL/mg)</b></p><br /> </td><br /> <td style="border-color: black black black currentcolor;border-style: solid solid solid none;border-width: 2px 2px 2px medium;width: 142px;padding: 0cm 7px" valign="top"><br /> <p align="center" style="text-align:center"><b>% Improvement<br><br /> over MCT<br><br /> Formulation<br><br /> (p value)</b></p><br /> </td><br /> <td style="border-color: black black black currentcolor;border-style: solid solid solid none;border-width: 2px 2px 2px medium;width: 142px;padding: 0cm 7px" valign="top"><br /> <p align="center" style="text-align:center"><b>% Improvement<br><br /> over original<br><br /> DehydraTECH 1.0<br><br /> (p value)</b></p><br /> </td><br /> <td style="border-color: black black black currentcolor;border-style: solid solid solid none;border-width: 2px 2px 2px medium;width: 132px;padding: 0cm 7px" valign="top"><br /> <p align="center" style="text-align:center"><b>% Improvement<br><br /> over original<br><br /> DehydraTECH 2.0 </b><br><br /> <b>(p value)</b></p><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <div style="text-align: center">MCT Control <sup>(2)</sup></div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center">13.17 ± 6.78</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <div style="text-align: center">Original <sup>(2) </sup>DehydraTECH 1.0</div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center">64.6 ± 23.7</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">390%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.00002)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-color: currentcolor black black;border-style: none solid solid;border-width: medium 2px 2px;width: 123px;padding: 0cm 7px" valign="top"><br /> <div style="text-align: center">Original <sup>(3) </sup><br><br /> DehydraTECH 2.0</div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center">134.7 ± 63.7</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">923%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.00009)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">108%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.0036)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">--</div><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <div style="text-align: center"><b>**NEW**</b> DehydraTECH 2.0 Formulation 1 <sup>(4)</sup></div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center"><br><br /> 153.9 ± 62.8</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">1,068%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.00003)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">138%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.0006)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">14%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.253)</div><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <div style="text-align: center"><b>**NEW**</b> DehydraTECH 2.0 Formulation 2 <sup>(4)</sup></div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center"><br><br /> 216.0 ± 94.9</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">1,540%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.00004)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">234%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.0003)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">60%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.018)</div><br /> </td><br /> </tr><br /> <tr><br /> <td style="border-bottom:2px solid black;width:123px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:2px solid black" valign="top"><br /> <div style="text-align: center"><b>**NEW**</b> DehydraTECH 2.0 Formulation 3 <sup>(4)</sup></div><br /> </td><br /> <td style="border-color: currentcolor black black currentcolor;border-style: none solid solid none;border-width: medium 2px 2px medium;width: 113px;padding: 0cm 7px" valign="top"><br /> <div align="center" style="text-align: center"><br><br /> 300.1 ± 126.6</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">2,178%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.00007)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:142px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">364%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.0002)</div><br /> </td><br /> <td style="border-bottom:2px solid black;width:132px;padding:0cm 7px 0cm 7px;border-top:none;border-right:2px solid black;border-left:none" valign="top"><br /> <div align="center" style="text-align: center">123%</div><br /> <br /> <div align="center" style="text-align: center">(p=0.002)</div><br /> </td><br /> </tr><br /> </tbody><br /> </table><br /> <br /> <ol><br /> <li>AUC: Area Under the Curve, or total CBD delivery into the rodent bloodstream</li><br /> <li>60-minute study duration</li><br /> <li>60-minute study duration evaluated in 2019</li><br /> <li>120-minute study duration evaluated in 2021</li><br /> </ol><br /> <br /> <p>"Not only did the three latest DehydraTECH 2.0 formulations deliver between 1,068% and 2,178% more CBD during the study period than the standard MCT control formulation, they also were up to 123% more effective than the original DehydraTECH 2.0 formulation," said Chris Bunka, CEO of Lexaria. "Said another way, for every 1 mg of CBD delivered by the industry standard MCT control formulation, these latest DehydraTECH 2.0 formulations delivered 10 to 21 mg of CBD."</p><br /> <br /> <p>The study demonstrated that each of the new DehydraTECH 2.0 formulations delivered very high levels of CBD absorption into brain tissues, dwarfing the levels achieved with the MCT oil-based control formulation. The three new DehydraTECH 2.0 formulations delivered between 907%-1,737% more CBD into brain tissue than the MCT oil based control formulation, similar to the up to 1,937% increase over the MCT oil based control formulation announced previously for Lexaria's original DehydraTECH 2.0 formulation.</p><br /> <br /> <p>In each arm of the study, ten male Sprague-Dawley rats were dosed orally at a level of 25 mg/Kg CBD, and over the next 120 minutes multiple measurements were made of delivery into the bloodstream and tissues comparing the DehydraTECH formulations to certain controls.</p><br /> <br /> <p>These study findings add significantly to Lexaria's body of evidence demonstrating the ability of its DehydraTECH technology to be engineered to enhance the delivery of lipophilic active ingredients such as CBD across a range of uptake levels, whereby higher delivery level targets may be most applicable to pharmaceutical dosage forms and lower delivery level targets more suited to consumer packaged goods.</p><br /> <br /> <p>Additional DehydraTECH 2.0 formulations are being evaluated in Lexaria study HYPER-A21-2 presently underway, and results are expected in late May or early June, 2021. Thereafter, Lexaria is planning additional work that will evaluate impacts upon real-time blood pressure in animals using select formulations pursuant to these studies. Lexaria will provide more details on this upcoming blood pressure testing in animals as they become available. As well, advanced DehydraTECH 2.0 formulations are already being used by Lexaria in ongoing human studies and will be monetized for commercial use when applicable.</p><br /> <br /> <p>*<i> Compared with control formula utilizing medium chain triglycerides (coconut oil)</i> <i>representative of standard industry practices</i></p><br /> <br /> <p><b>About Lexaria Bioscience Corp.</b></p><br /> <br /> <p>Lexaria Bioscience Corp.'s proprietary drug delivery technology, DehydraTECH™, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream by promoting healthier oral ingestion methods and increasing the effectiveness of fat-soluble active molecules, thereby lowering overall dosing. The Company's technology can be applied to many different ingestible product formats, including foods, beverages, oral suspensions, tablets, and capsules. DehydraTECH has repeatedly demonstrated since 2016 with cannabinoids and nicotine the ability to increase bio-absorption by up to 5-10x, reduce time of onset from 1 - 2 hours to minutes, and mask unwanted tastes; and is planned to be further evaluated for orally administered bioactive molecules, including anti-virals, cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), and nicotine. Lexaria has licensed DehydraTECH to multiple companies including a world-leading tobacco producer for the development of smokeless, oral-based nicotine products and for use in industries that produce cannabinoid beverages, edibles, and oral products. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 18 patents granted and approximately 60 patents pending worldwide. For more information, please visit <a href="https://pr.report/fKBIJPU-">www.lexariabioscience.com</a>.</p><br /> <br /> <p><b>CAUTION REGARDING FORWARD-LOOKING STATEMENTS</b></p><br /> <br /> <p>This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.</p><br /> <br /> <p><i>The CSE has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.</i></p><br /> <br /> <p><b>INVESTOR CONTACT: </b></p><br /> <br /> <p><a href="/cdn-cgi/l/email-protection#1d746f5d7178657c6f747c7f74726e7e7478737e78337e7270"><span class="__cf_email__" data-cfemail="ff968dbf939a879e8d969e9d96908c9c969a919c9ad19c9092">[email protected]</span></a><br><br /> Phone: 866-221-3341</p><br /> <br /> <p><strong>SOURCE:</strong> Lexaria Bioscience Corp.</p><br /> <br><br>View source version on accesswire.com: <br><a href='https://www.accesswire.com/644927/Lexaria-Issues-Successful-Results-from-First-2021-Study-HYPER-A21-1'>https://www.accesswire.com/644927/Lexaria-Issues-Successful-Results-from-First-2021-Study-HYPER-A21-1</a><br><br><img src='https://www.accesswire.com/img.ashx?id=644927' /></div></div> <div class="themestek-blog-classic-footer-readmore"> <div class="themestek-blogbox-footer-left"><a href="https://lexariabioscience.com/2021/05/06/lexaria-issues-successful-results-from-first-2021-study-hyper-a21-1/">Read More</a></div> </div> <div class="ts-footer-meta-wrapper"> <span class="ts-footer-meta-line-w ts-footer-meta-line-comments"> <a href="https://lexariabioscience.com/2021/05/06/lexaria-issues-successful-results-from-first-2021-study-hyper-a21-1/"> <i class="ts-labtechco-icon-comment-1"></i> <span class="comments"> 0 Comments </span> </a> </span> <span class="ts-footer-meta-line-w ts-footer-meta-line-author"> <span class="author vcard"> <span class="screen-reader-text ts-hide">Author 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