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.infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Modimelanotide">Modimelanotide</span></caption><tbody><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span typeof="mw:File"><a href="/wiki/File:Modimelanotide.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Modimelanotide.svg/250px-Modimelanotide.svg.png" decoding="async" width="250" height="69" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Modimelanotide.svg/375px-Modimelanotide.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/08/Modimelanotide.svg/500px-Modimelanotide.svg.png 2x" data-file-width="7193" data-file-height="1973" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Other names</th><td class="infobox-data">Acetylhexa-<small>L</small>-lysyl-α-MSH</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li>None</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;"><small>N2-acetyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide</small></div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=926277-68-1">926277-68-1</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/72941953">72941953</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.34988374.html">34988374</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/96C1EBE9CG">96C1EBE9CG</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID001032325">DTXSID001032325</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q20707053#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>113</sub><span title="Hydrogen">H</span><sub>181</sub><span title="Nitrogen">N</span><sub>33</sub><span title="Oxygen">O</span><sub>25</sub><span title="Sulfur">S</span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7003243396000000000♠"></span>2<span style="margin-left:.25em;">433</span>.96</span> g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=%5BH%5D%2FN%3DC%28%5CN%29%2FNCCC%5BC%40%40H%5D%28C%28%3DO%29N%5BC%40%40H%5D%28Cc1c%5BnH%5Dc2c1cccc2%29C%28%3DO%29NCC%28%3DO%29N%5BC%40%40H%5D%28CCCCN%29C%28%3DO%29N3CCC%5BC%40H%5D3C%28%3DO%29N%5BC%40%40H%5D%28C%28C%29C%29C%28%3DO%29N%29NC%28%3DO%29%5BC%40H%5D%28Cc4ccccc4%29NC%28%3DO%29%5BC%40H%5D%28Cc5c%5BnH%5Dcn5%29NC%28%3DO%29%5BC%40H%5D%28CCC%28%3DO%29O%29NC%28%3DO%29%5BC%40H%5D%28CCSC%29NC%28%3DO%29%5BC%40H%5D%28CO%29NC%28%3DO%29%5BC%40H%5D%28Cc6ccc%28cc6%29O%29NC%28%3DO%29%5BC%40H%5D%28CO%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29%5BC%40H%5D%28CCCCN%29NC%28%3DO%29C">Interactive image</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">[H]/N=C(\N)/NCCC[C@@H](C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N3CCC[C@H]3C(=O)N[C@@H](C(C)C)C(=O)N)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc6ccc(cc6)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)C</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C113H181N33O25S/c1-66(2)94(95(121)154)145-111(170)91-38-25-54-146(91)112(171)84(36-16-23-52-120)130-92(151)62-127-96(155)87(58-70-60-126-74-29-9-8-28-73(70)74)141-102(161)81(37-24-53-125-113(122)123)136-106(165)85(56-68-26-6-5-7-27-68)139-108(167)88(59-71-61-124-65-128-71)142-104(163)82(43-44-93(152)153)137-105(164)83(45-55-172-4)138-109(168)89(63-147)144-107(166)86(57-69-39-41-72(150)42-40-69)140-110(169)90(64-148)143-103(162)80(35-15-22-51-119)135-101(160)79(34-14-21-50-118)134-100(159)78(33-13-20-49-117)133-99(158)77(32-12-19-48-116)132-98(157)76(31-11-18-47-115)131-97(156)75(129-67(3)149)30-10-17-46-114/h5-9,26-29,39-42,60-61,65-66,75-91,94,126,147-148,150H,10-25,30-38,43-59,62-64,114-120H2,1-4H3,(H2,121,154)(H,124,128)(H,127,155)(H,129,149)(H,130,151)(H,131,156)(H,132,157)(H,133,158)(H,134,159)(H,135,160)(H,136,165)(H,137,164)(H,138,168)(H,139,167)(H,140,169)(H,141,161)(H,142,163)(H,143,162)(H,144,166)(H,145,170)(H,152,153)(H4,122,123,125)/t75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,94-/m0/s1</div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:WHRVKPBBRZHWTN-ZHHKRVSMSA-N</div></li></ul> </div></td></tr></tbody></table> <p><b>Modimelanotide</b> (<a href="/wiki/International_Nonproprietary_Name" class="mw-redirect" title="International Nonproprietary Name">INN</a>) (code names <b>AP-214</b>, <b>ABT-719</b>, <b>ZP-1480</b>) is a <a href="/wiki/Melanocortin" title="Melanocortin">melanocortinergic</a> <a href="/wiki/Peptide" title="Peptide">peptide</a> <a href="/wiki/Drug" title="Drug">drug</a> derived from <a href="/wiki/%CE%91-melanocyte-stimulating_hormone" class="mw-redirect" title="Α-melanocyte-stimulating hormone">α-melanocyte-stimulating hormone</a> (α-MSH) which was under development by, at different times, <a href="/w/index.php?title=Action_Pharma&action=edit&redlink=1" class="new" title="Action Pharma (page does not exist)">Action Pharma</a>, <a href="/wiki/Abbott_Laboratories" title="Abbott Laboratories">Abbott Laboratories</a>, <a href="/wiki/AbbVie" title="AbbVie">AbbVie</a>, and <a href="/w/index.php?title=Zealand_(pharmaceutical_company)&action=edit&redlink=1" class="new" title="Zealand (pharmaceutical company) (page does not exist)">Zealand</a> for the treatment of <a href="/wiki/Acute_kidney_injury" title="Acute kidney injury">acute kidney injury</a>.<sup id="cite_ref-RamosGonzález-Guerrero2015_1-0" class="reference"><a href="#cite_note-RamosGonzález-Guerrero2015-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Montero-Melendez2015_2-0" class="reference"><a href="#cite_note-Montero-Melendez2015-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It acts as a non-selective <a href="/wiki/Melanocortin_receptor" title="Melanocortin receptor">melanocortin receptor</a> <a href="/wiki/Agonist" title="Agonist">agonist</a>, with <a href="/wiki/IC50" title="IC50">IC<sub>50</sub></a> values of 2.9 nM, 1.9 nM, 3.7 nM, and 110 nM at the <a href="/wiki/Melanocortin_1_receptor" title="Melanocortin 1 receptor">MC<sub>1</sub></a>, <a href="/wiki/Melanocortin_3_receptor" title="Melanocortin 3 receptor">MC<sub>3</sub></a>, <a href="/wiki/Melanocortin_4_receptor" title="Melanocortin 4 receptor">MC<sub>4</sub></a>, and <a href="/wiki/Melanocortin_5_receptor" title="Melanocortin 5 receptor">MC<sub>5</sub> receptors</a>.<sup id="cite_ref-issn0379-4121_3-0" class="reference"><a href="#cite_note-issn0379-4121-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Modimelanotide failed <a href="/wiki/Clinical_trial" title="Clinical trial">clinical trials</a> for acute kidney injury despite showing efficacy in <a href="/wiki/Animal_model" class="mw-redirect" title="Animal model">animal models</a>,<sup id="cite_ref-DoiHu2008_4-0" class="reference"><a href="#cite_note-DoiHu2008-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimmonsSubramanian2010_5-0" class="reference"><a href="#cite_note-SimmonsSubramanian2010-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> and development was not further pursued.<sup id="cite_ref-RamosGonzález-Guerrero2015_1-1" class="reference"><a href="#cite_note-RamosGonzález-Guerrero2015-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Montero-Melendez2015_2-1" class="reference"><a href="#cite_note-Montero-Melendez2015-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Modimelanotide&action=edit&section=1" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Afamelanotide" title="Afamelanotide">Afamelanotide</a></li> <li><a href="/wiki/BMS-470,539" class="mw-redirect" title="BMS-470,539">BMS-470,539</a></li> <li><a href="/wiki/Bremelanotide" title="Bremelanotide">Bremelanotide</a></li> <li><a href="/wiki/Melanotan_II" title="Melanotan II">Melanotan II</a></li> <li><a href="/wiki/PF-00446687" title="PF-00446687">PF-00446687</a></li> <li><a href="/wiki/Setmelanotide" title="Setmelanotide">Setmelanotide</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Modimelanotide&action=edit&section=2" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-RamosGonzález-Guerrero2015-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-RamosGonzález-Guerrero2015_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-RamosGonzález-Guerrero2015_1-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFRamosGonzález-GuerreroSanzSanchez-Niño2015" class="citation journal cs1">Ramos AM, González-Guerrero C, Sanz A, Sanchez-Niño MD, Rodríguez-Osorio L, Martín-Cleary C, et al. (May 2015). "Designing drugs that combat kidney damage". <i>Expert Opinion on Drug Discovery</i>. <b>10</b> (5): 541–56. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1517%2F17460441.2015.1033394">10.1517/17460441.2015.1033394</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25840605">25840605</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:24191324">24191324</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Expert+Opinion+on+Drug+Discovery&rft.atitle=Designing+drugs+that+combat+kidney+damage&rft.volume=10&rft.issue=5&rft.pages=541-56&rft.date=2015-05&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A24191324%23id-name%3DS2CID&rft_id=info%3Apmid%2F25840605&rft_id=info%3Adoi%2F10.1517%2F17460441.2015.1033394&rft.aulast=Ramos&rft.aufirst=AM&rft.au=Gonz%C3%A1lez-Guerrero%2C+C&rft.au=Sanz%2C+A&rft.au=Sanchez-Ni%C3%B1o%2C+MD&rft.au=Rodr%C3%ADguez-Osorio%2C+L&rft.au=Mart%C3%ADn-Cleary%2C+C&rft.au=Fern%C3%A1ndez-Fern%C3%A1ndez%2C+B&rft.au=Ruiz-Ortega%2C+M&rft.au=Ortiz%2C+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3AModimelanotide" class="Z3988"></span></span> </li> <li id="cite_note-Montero-Melendez2015-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-Montero-Melendez2015_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Montero-Melendez2015_2-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMontero-Melendez2015" class="citation journal cs1">Montero-Melendez T (May 2015). "ACTH: The forgotten therapy". <i>Seminars in Immunology</i>. <b>27</b> (3): 216–26. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.smim.2015.02.003">10.1016/j.smim.2015.02.003</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25726511">25726511</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Seminars+in+Immunology&rft.atitle=ACTH%3A+The+forgotten+therapy&rft.volume=27&rft.issue=3&rft.pages=216-26&rft.date=2015-05&rft_id=info%3Adoi%2F10.1016%2Fj.smim.2015.02.003&rft_id=info%3Apmid%2F25726511&rft.aulast=Montero-Melendez&rft.aufirst=T&rfr_id=info%3Asid%2Fen.wikipedia.org%3AModimelanotide" class="Z3988"></span></span> </li> <li id="cite_note-issn0379-4121-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-issn0379-4121_3-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation journal cs1"><a rel="nofollow" class="external text" href="https://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summary_pr?p_JournalId=1&p_RefId=3563&p_IsPs=Y">"Renal-Urologic drugs"</a>. <i>Drug Data Reports</i>. <b>29</b> (1). Prous Science: 42. 2007. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0379-4121">0379-4121</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Drug+Data+Reports&rft.atitle=Renal-Urologic+drugs&rft.volume=29&rft.issue=1&rft.pages=42&rft.date=2007&rft.issn=0379-4121&rft_id=https%3A%2F%2Fjournals.prous.com%2Fjournals%2Fservlet%2Fxmlxsl%2Fpk_journals.xml_summary_pr%3Fp_JournalId%3D1%26p_RefId%3D3563%26p_IsPs%3DY&rfr_id=info%3Asid%2Fen.wikipedia.org%3AModimelanotide" class="Z3988"></span></span> </li> <li id="cite_note-DoiHu2008-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-DoiHu2008_4-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDoiHuYuenLeelahavanichkul2008" class="citation journal cs1">Doi K, Hu X, Yuen PS, Leelahavanichkul A, Yasuda H, Kim SM, et al. (June 2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398767">"AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality"</a>. <i>Kidney International</i>. <b>73</b> (11): 1266–74. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fki.2008.97">10.1038/ki.2008.97</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398767">2398767</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18354376">18354376</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Kidney+International&rft.atitle=AP214%2C+an+analogue+of+alpha-melanocyte-stimulating+hormone%2C+ameliorates+sepsis-induced+acute+kidney+injury+and+mortality&rft.volume=73&rft.issue=11&rft.pages=1266-74&rft.date=2008-06&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2398767%23id-name%3DPMC&rft_id=info%3Apmid%2F18354376&rft_id=info%3Adoi%2F10.1038%2Fki.2008.97&rft.aulast=Doi&rft.aufirst=K&rft.au=Hu%2C+X&rft.au=Yuen%2C+PS&rft.au=Leelahavanichkul%2C+A&rft.au=Yasuda%2C+H&rft.au=Kim%2C+SM&rft.au=Schnermann%2C+J&rft.au=Jonassen%2C+TE&rft.au=Fr%C3%B8kiaer%2C+J&rft.au=Nielsen%2C+S&rft.au=Star%2C+RA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2398767&rfr_id=info%3Asid%2Fen.wikipedia.org%3AModimelanotide" class="Z3988"></span></span> </li> <li id="cite_note-SimmonsSubramanian2010-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-SimmonsSubramanian2010_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSimmonsSubramanianCrouzetHaber2010" class="citation journal cs1">Simmons MN, Subramanian V, Crouzet S, Haber GP, Colombo JR, Ukimura O, et al. (April 2010). "Alpha-melanocyte stimulating hormone analogue AP214 protects against ischemia induced acute kidney injury in a porcine surgical model". <i>The Journal of Urology</i>. <b>183</b> (4): 1625–9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.juro.2009.12.007">10.1016/j.juro.2009.12.007</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20172543">20172543</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Urology&rft.atitle=Alpha-melanocyte+stimulating+hormone+analogue+AP214+protects+against+ischemia+induced+acute+kidney+injury+in+a+porcine+surgical+model&rft.volume=183&rft.issue=4&rft.pages=1625-9&rft.date=2010-04&rft_id=info%3Adoi%2F10.1016%2Fj.juro.2009.12.007&rft_id=info%3Apmid%2F20172543&rft.aulast=Simmons&rft.aufirst=MN&rft.au=Subramanian%2C+V&rft.au=Crouzet%2C+S&rft.au=Haber%2C+GP&rft.au=Colombo%2C+JR&rft.au=Ukimura%2C+O&rft.au=Nielsen%2C+S&rft.au=Neilsen%2C+S&rft.au=Gill%2C+IS&rfr_id=info%3Asid%2Fen.wikipedia.org%3AModimelanotide" class="Z3988"></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Modimelanotide&action=edit&section=3" title="Edit section: External links"><span>edit</span></a><span 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.navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="Melanocortin_receptor_modulators" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Melanocortin_receptor_modulators" title="Template:Melanocortin receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Melanocortin_receptor_modulators" title="Template talk:Melanocortin receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Melanocortin_receptor_modulators" title="Special:EditPage/Template:Melanocortin receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Melanocortin_receptor_modulators" style="font-size:114%;margin:0 4em"><a href="/wiki/Melanocortin_receptor" title="Melanocortin receptor">Melanocortin receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Melanocortin_1_receptor" title="Melanocortin 1 receptor">MC<sub>1</sub></a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Adrenocorticotropic_hormone" title="Adrenocorticotropic hormone">ACTH (corticotropin)</a></li> <li><a href="/wiki/Afamelanotide" title="Afamelanotide">Afamelanotide (melanotan I)</a></li> <li><a href="/wiki/BMS-470539" title="BMS-470539">BMS-470539</a></li> <li><a href="/wiki/Bremelanotide" title="Bremelanotide">Bremelanotide</a></li> <li><a href="/w/index.php?title=HS-014&action=edit&redlink=1" class="new" title="HS-014 (page does not exist)">HS-014</a></li> <li><a href="/w/index.php?title=HS-024&action=edit&redlink=1" class="new" title="HS-024 (page does not exist)">HS-024</a></li> <li><a href="/wiki/Melanocyte-stimulating_hormone" title="Melanocyte-stimulating hormone">MSH</a> (<a href="/wiki/%CE%91-MSH" class="mw-redirect" title="Α-MSH">α</a>, <a href="/wiki/%CE%92-MSH" class="mw-redirect" title="Β-MSH">β</a>, <a href="/wiki/%CE%93-MSH" class="mw-redirect" title="Γ-MSH">γ</a>)</li> <li><a href="/wiki/Melanotan_II" title="Melanotan II">Melanotan II</a></li> <li><a class="mw-selflink selflink">Modimelanotide</a></li> <li><a href="/w/index.php?title=PL-8177&action=edit&redlink=1" class="new" title="PL-8177 (page does not exist)">PL-8177</a></li> <li><a href="/w/index.php?title=SHU-8914&action=edit&redlink=1" class="new" title="SHU-8914 (page does not exist)">SHU-8914</a></li> <li><a href="/w/index.php?title=SHU-9005&action=edit&redlink=1" class="new" title="SHU-9005 (page does not exist)">SHU-9005</a></li> <li><a href="/w/index.php?title=SHU-9119&action=edit&redlink=1" class="new" title="SHU-9119 (page does not exist)">SHU-9119</a></li> <li><a href="/wiki/SNAP-7941" title="SNAP-7941">SNAP-7941</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/Agouti_signalling_peptide" class="mw-redirect" title="Agouti signalling peptide">ASIP</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/ACTH_receptor" title="ACTH receptor">MC<sub>2</sub></a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Adrenocorticotropic_hormone" title="Adrenocorticotropic hormone">ACTH (corticotropin)</a></li> <li><a href="/wiki/Alsactide" title="Alsactide">Alsactide</a></li> <li><a href="/w/index.php?title=Codactide&action=edit&redlink=1" class="new" title="Codactide (page does not exist)">Codactide</a></li> <li><a href="/w/index.php?title=Giractide&action=edit&redlink=1" class="new" title="Giractide (page does not exist)">Giractide</a></li> <li><a href="/w/index.php?title=Norleusactide&action=edit&redlink=1" class="new" title="Norleusactide (page does not exist)">Norleusactide (pentacosactride)</a></li> <li><a href="/w/index.php?title=Seractide&action=edit&redlink=1" class="new" title="Seractide (page does not exist)">Seractide</a></li> <li><a href="/wiki/Tetracosactide" class="mw-redirect" title="Tetracosactide">Tetracosactide (tetracosactrin, cosyntropin)</a></li> <li><a href="/w/index.php?title=Tosactide&action=edit&redlink=1" class="new" title="Tosactide (page does not exist)">Tosactide (octacosactrin)</a></li> <li><a href="/w/index.php?title=Tricosactide&action=edit&redlink=1" class="new" title="Tricosactide (page does not exist)">Tricosactide</a></li> <li><a href="/w/index.php?title=Tridecactide&action=edit&redlink=1" class="new" title="Tridecactide (page does not exist)">Tridecactide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Melanocortin_3_receptor" title="Melanocortin 3 receptor">MC<sub>3</sub></a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Adrenocorticotropic_hormone" title="Adrenocorticotropic hormone">ACTH (corticotropin)</a></li> <li><a href="/wiki/Afamelanotide" title="Afamelanotide">Afamelanotide (melanotan I)</a></li> <li><a href="/wiki/Bremelanotide" title="Bremelanotide">Bremelanotide</a></li> <li><a href="/wiki/Melanocyte-stimulating_hormone" title="Melanocyte-stimulating hormone">MSH</a> (<a href="/wiki/%CE%91-MSH" class="mw-redirect" title="Α-MSH">α</a>, <a href="/wiki/%CE%92-MSH" class="mw-redirect" title="Β-MSH">β</a>, <a href="/wiki/%CE%93-MSH" class="mw-redirect" title="Γ-MSH">γ</a>)</li> <li><a href="/wiki/Melanotan_II" title="Melanotan II">Melanotan II</a></li> <li><a class="mw-selflink selflink">Modimelanotide</a></li> <li><a href="/w/index.php?title=PG-931&action=edit&redlink=1" class="new" title="PG-931 (page does not exist)">PG-931</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/Agouti-related_peptide" title="Agouti-related peptide">AGRP</a></li> <li><a href="/wiki/Agouti_signalling_peptide" class="mw-redirect" title="Agouti signalling peptide">ASIP</a></li> <li><a href="/w/index.php?title=HS-014&action=edit&redlink=1" class="new" title="HS-014 (page does not exist)">HS-014</a></li> <li><a href="/w/index.php?title=ML-00253764&action=edit&redlink=1" class="new" title="ML-00253764 (page does not exist)">ML-00253764</a></li> <li><a href="/w/index.php?title=PG-106&action=edit&redlink=1" class="new" title="PG-106 (page does not exist)">PG-106</a></li> <li><a href="/w/index.php?title=SHU-8914&action=edit&redlink=1" class="new" title="SHU-8914 (page does not exist)">SHU-8914</a></li> <li><a href="/w/index.php?title=SHU-9005&action=edit&redlink=1" class="new" title="SHU-9005 (page does not exist)">SHU-9005</a></li> <li><a href="/w/index.php?title=SHU-9119&action=edit&redlink=1" class="new" title="SHU-9119 (page does not exist)">SHU-9119</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Melanocortin_4_receptor" title="Melanocortin 4 receptor">MC<sub>4</sub></a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Adrenocorticotropic_hormone" title="Adrenocorticotropic hormone">ACTH (corticotropin)</a></li> <li><a href="/wiki/Afamelanotide" title="Afamelanotide">Afamelanotide (melanotan I)</a></li> <li><a href="/w/index.php?title=AZD2820&action=edit&redlink=1" class="new" title="AZD2820 (page does not exist)">AZD2820</a></li> <li><a href="/wiki/BIM-22493" class="mw-redirect" title="BIM-22493">BIM-22493</a></li> <li><a href="/wiki/Bremelanotide" title="Bremelanotide">Bremelanotide</a></li> <li><a href="/w/index.php?title=LY-2112688&action=edit&redlink=1" class="new" title="LY-2112688 (page does not exist)">LY-2112688</a></li> <li><a href="/wiki/Melanocyte-stimulating_hormone" title="Melanocyte-stimulating hormone">MSH</a> (<a href="/wiki/%CE%91-MSH" class="mw-redirect" title="Α-MSH">α</a>, <a href="/wiki/%CE%92-MSH" class="mw-redirect" title="Β-MSH">β</a>, <a href="/wiki/%CE%93-MSH" class="mw-redirect" title="Γ-MSH">γ</a>)</li> <li><a href="/wiki/Melanotan_II" title="Melanotan II">Melanotan II</a></li> <li><a href="/w/index.php?title=MK-0493&action=edit&redlink=1" class="new" title="MK-0493 (page does not exist)">MK-0493</a></li> <li><a class="mw-selflink selflink">Modimelanotide</a></li> <li><a href="/wiki/PF-00446687" title="PF-00446687">PF-00446687</a></li> <li><a href="/w/index.php?title=PG-931&action=edit&redlink=1" class="new" title="PG-931 (page does not exist)">PG-931</a></li> <li><a href="/wiki/PL-6983" title="PL-6983">PL-6983</a></li> <li><a href="/w/index.php?title=Ro_27-3225&action=edit&redlink=1" class="new" title="Ro 27-3225 (page does not exist)">Ro 27-3225</a></li> <li><a href="/wiki/Setmelanotide" title="Setmelanotide">Setmelanotide</a></li> <li><a href="/wiki/THIQ" title="THIQ">THIQ</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/Agouti-related_peptide" title="Agouti-related peptide">AGRP</a></li> <li><a href="/wiki/Agouti_signalling_peptide" class="mw-redirect" title="Agouti signalling peptide">ASIP</a></li> <li><a href="/w/index.php?title=HS-014&action=edit&redlink=1" class="new" title="HS-014 (page does not exist)">HS-014</a></li> <li><a href="/w/index.php?title=HS-024&action=edit&redlink=1" class="new" title="HS-024 (page does not exist)">HS-024</a></li> <li><a href="/w/index.php?title=HS-131&action=edit&redlink=1" class="new" title="HS-131 (page does not exist)">HS-131</a></li> <li><a href="/w/index.php?title=JKC-363&action=edit&redlink=1" class="new" title="JKC-363 (page does not exist)">JKC-363</a></li> <li><a href="/w/index.php?title=MCL-0020&action=edit&redlink=1" class="new" title="MCL-0020 (page does not exist)">MCL-0020</a></li> <li><a href="/w/index.php?title=MCL-0042&action=edit&redlink=1" class="new" title="MCL-0042 (page does not exist)">MCL-0042</a></li> <li><a href="/w/index.php?title=MCL-0129&action=edit&redlink=1" class="new" title="MCL-0129 (page does not exist)">MCL-0129</a></li> <li><a href="/w/index.php?title=ML-00253764&action=edit&redlink=1" class="new" title="ML-00253764 (page does not exist)">ML-00253764</a></li> <li><a href="/w/index.php?title=MPB-10&action=edit&redlink=1" class="new" title="MPB-10 (page does not exist)">MPB-10</a></li> <li><a href="/w/index.php?title=SHU-8914&action=edit&redlink=1" class="new" title="SHU-8914 (page does not exist)">SHU-8914</a></li> <li><a href="/w/index.php?title=SHU-9005&action=edit&redlink=1" class="new" title="SHU-9005 (page does not exist)">SHU-9005</a></li> <li><a href="/w/index.php?title=SHU-9119&action=edit&redlink=1" class="new" title="SHU-9119 (page does not exist)">SHU-9119</a></li></ul> <ul><li><b>Unknown:</b> <a href="/wiki/Semax" title="Semax">Semax</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Melanocortin_5_receptor" title="Melanocortin 5 receptor">MC<sub>5</sub></a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Adrenocorticotropic_hormone" title="Adrenocorticotropic hormone">ACTH (corticotropin)</a></li> <li><a href="/wiki/Afamelanotide" title="Afamelanotide">Afamelanotide (melanotan I)</a></li> <li><a href="/wiki/Bremelanotide" title="Bremelanotide">Bremelanotide</a></li> <li><a href="/w/index.php?title=HS-014&action=edit&redlink=1" class="new" title="HS-014 (page does not exist)">HS-014</a></li> <li><a href="/w/index.php?title=HS-024&action=edit&redlink=1" class="new" title="HS-024 (page does not exist)">HS-024</a></li> <li><a href="/wiki/Melanocyte-stimulating_hormone" title="Melanocyte-stimulating hormone">MSH</a> (<a href="/wiki/%CE%91-MSH" class="mw-redirect" title="Α-MSH">α</a>, <a href="/wiki/%CE%92-MSH" class="mw-redirect" title="Β-MSH">β</a>, <a href="/wiki/%CE%93-MSH" class="mw-redirect" title="Γ-MSH">γ</a>)</li> <li><a href="/wiki/Melanotan_II" title="Melanotan II">Melanotan II</a></li> <li><a class="mw-selflink selflink">Modimelanotide</a></li> <li><a href="/w/index.php?title=SHU-8914&action=edit&redlink=1" class="new" title="SHU-8914 (page does not exist)">SHU-8914</a></li> <li><a href="/w/index.php?title=SHU-9005&action=edit&redlink=1" class="new" title="SHU-9005 (page does not exist)">SHU-9005</a></li> <li><a href="/w/index.php?title=SHU-9119&action=edit&redlink=1" class="new" title="SHU-9119 (page does not exist)">SHU-9119</a></li></ul> <ul><li><b>Antagonists:</b> <a href="/wiki/Agouti_signalling_peptide" class="mw-redirect" title="Agouti signalling peptide">ASIP</a></li> <li><a href="/w/index.php?title=ML-00253764&action=edit&redlink=1" class="new" title="ML-00253764 (page does not exist)">ML-00253764</a></li></ul> <ul><li><b>Unknown:</b> <a href="/wiki/Semax" title="Semax">Semax</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Unsorted</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Agonists:</b> <a href="/wiki/Alsactide" title="Alsactide">Alsactide</a></li> <li><a href="/w/index.php?title=Codactide&action=edit&redlink=1" class="new" title="Codactide (page does not exist)">Codactide</a></li> <li><a href="/w/index.php?title=Dersimelagon&action=edit&redlink=1" class="new" title="Dersimelagon (page does not exist)">Dersimelagon</a></li> <li><a href="/w/index.php?title=Giractide&action=edit&redlink=1" class="new" title="Giractide (page does not exist)">Giractide</a></li> <li><a href="/w/index.php?title=Norleusactide&action=edit&redlink=1" class="new" title="Norleusactide (page does not exist)">Norleusactide (pentacosactride)</a></li> <li><a href="/w/index.php?title=Seractide&action=edit&redlink=1" class="new" title="Seractide (page does not exist)">Seractide</a></li> <li><a href="/wiki/Tetracosactide" class="mw-redirect" title="Tetracosactide">Tetracosactide (tetracosactrin, cosyntropin)</a></li> <li><a href="/w/index.php?title=Tosactide&action=edit&redlink=1" class="new" title="Tosactide (page does not exist)">Tosactide (octacosactrin)</a></li> <li><a href="/w/index.php?title=Tricosactide&action=edit&redlink=1" class="new" title="Tricosactide (page does not exist)">Tricosactide</a></li> <li><a href="/w/index.php?title=Tridecactide&action=edit&redlink=1" class="new" title="Tridecactide (page does not exist)">Tridecactide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>Propeptides:</b> <a href="/wiki/Lipotropin" title="Lipotropin">Lipotropin</a> (<a href="/wiki/%CE%92-Lipotropin" class="mw-redirect" title="Β-Lipotropin">β</a>, <a href="/wiki/%CE%93-Lipotropin" class="mw-redirect" title="Γ-Lipotropin">γ</a>)</li> <li><a href="/wiki/N-Terminal_peptide_of_proopiomelanocortin" title="N-Terminal peptide of proopiomelanocortin">N-POMC (NPP, pro-γ-MSH)</a></li> <li><a href="/wiki/Proopiomelanocortin" title="Proopiomelanocortin">Proopiomelanocortin (POMC)</a></li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/File:Progesterone-3D-vdW.png" class="mw-file-description"><img alt="Stub icon" 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