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</header><div class="mh-section mh-group"> <div id="main-content" class="mh-loop"><h1 class="page-title">Volume 2 Issue 1</h1> <article class="content-lead post-254 post type-post status-publish format-standard hentry category-v2n1">  <h3 class="content-list-title"><a href="https://jaddictionscience.com/2016/08/19/review-and-recommendations-for-drug-testing-in-substance-use-treatment-contexts/" title="Review and Recommendations for Drug Testing in Substance Use Treatment Contexts" rel="bookmark">Review and Recommendations for Drug Testing in Substance Use Treatment Contexts</a></h3> <div class="content-lead-excerpt"> <p><i>Adi Jaffe, Sean Molnar, Nicole Williams, Emily Wong, Therese Todd, et al.</i><br/> Drug and alcohol use have been associated with substantial impairments in functioning in a number of settings including driving [1], the work place [2], family functioning [3] and military service [4, 5]. </p> <a class="button" href="https://jaddictionscience.com/2016/08/19/review-and-recommendations-for-drug-testing-in-substance-use-treatment-contexts/"> <span>Read More</span> </a> </div> </article> <hr class="mh-separator"><article class="content-list clearfix post-250 post type-post status-publish format-standard hentry category-v2n1">  <header class="content-list-header"> <p class="entry-meta"> </p> <h3 class="content-list-title"><a href="https://jaddictionscience.com/2016/06/30/internet-addiction-by-using-the-smartphone-relationships-between-internet-addiction-frequency-of-smartphone-use-and-the-state-of-mind-of-male-and-female-students/" title="Internet Addiction by Using the Smartphone-Relationships between Internet Addiction, Frequency of Smartphone Use and the State of Mind of Male and Female Students" rel="bookmark">Internet Addiction by Using the Smartphone-Relationships between Internet Addiction, Frequency of Smartphone Use and the State of Mind of Male and Female Students</a></h3> </header> <div class="content-list-excerpt"> <p><i>Liron Ben-Yehuda, Liel Greenberg and Aviv Weinstein</i><br/> In recent years, the use of Smartphones got a lot of attention due to their possible physiological, psychological and behavioral effects.</p> <a class="button" href="https://jaddictionscience.com/2016/06/30/internet-addiction-by-using-the-smartphone-relationships-between-internet-addiction-frequency-of-smartphone-use-and-the-state-of-mind-of-male-and-female-students/"> <span>Read More</span> </a> </div> </article> <hr class="mh-separator content-list-separator"><article class="content-list clearfix post-245 post type-post status-publish format-standard hentry category-v2n1">  <header class="content-list-header"> <p class="entry-meta"> </p> <h3 class="content-list-title"><a href="https://jaddictionscience.com/2016/06/29/hypothesizing-that-a-pro-dopamine-regulator-kb220z-should-optimize-but-not-hyper-activate-the-activity-of-trace-amine-associated-receptor-1-taar-1-and-induce-anti-craving-of-psychostimulants-in/" title="Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term" rel="bookmark">Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term</a></h3> </header> <div class="content-list-excerpt"> <p><i>Kenneth Blum, Rajendra D. Badgaiyan, Eric R. Braverman, Kristina Dushaj, Mona Li, et al</i><br/> Unlike other drugs of abuse such as alcohol, nicotine, opiates/opioids, the FDA has not approved any agent to treat psychostimulant dependence. Certainly, it is widely acceptable that dopaminergic signaling is a key factor in both the initiation and continued motivation to abuse this class of stimulant substances.</p> <a class="button" href="https://jaddictionscience.com/2016/06/29/hypothesizing-that-a-pro-dopamine-regulator-kb220z-should-optimize-but-not-hyper-activate-the-activity-of-trace-amine-associated-receptor-1-taar-1-and-induce-anti-craving-of-psychostimulants-in/"> <span>Read More</span> </a> </div> </article> <hr class="mh-separator content-list-separator"><article class="content-list clearfix post-242 post type-post status-publish format-standard hentry category-v2n1">  <header class="content-list-header"> <p class="entry-meta"> </p> <h3 class="content-list-title"><a href="https://jaddictionscience.com/2016/05/19/kb220z-a-pro-dopamine-regulator-associated-with-the-protracted-alleviation-of-terrifying-lucid-dreams-can-we-infer-neuroplasticity-induced-changes-in-the-reward-circuit/" title="KB220Z™ a Pro-Dopamine Regulator Associated with the Protracted, Alleviation of Terrifying Lucid Dreams. Can We Infer Neuroplasticity-induced Changes in the Reward Circuit?" rel="bookmark">KB220Z™ a Pro-Dopamine Regulator Associated with the Protracted, Alleviation of Terrifying Lucid Dreams. Can We Infer Neuroplasticity-induced Changes in the Reward Circuit?</a></h3> </header> <div class="content-list-excerpt"> <p><i>Thomas McLaughlin, Marcelo Febo, Thomas Simpatico, Rajendra D. Badgaiyan, Debmalya Barh, et al.</i><br/> Major Depressive Disorder (MDD) is a condition that affects approximately 12% of the population [1] and recurs at a rate between 50-85% regardless of treatment [2]. Treatment resistant depression (TRD) is considered if patients<br/> do not show alleviation of depressive symptoms after at least two trials of antidepressants from different pharmacologic classes [3].</p> <a class="button" href="https://jaddictionscience.com/2016/05/19/kb220z-a-pro-dopamine-regulator-associated-with-the-protracted-alleviation-of-terrifying-lucid-dreams-can-we-infer-neuroplasticity-induced-changes-in-the-reward-circuit/"> <span>Read More</span> </a> </div> </article> <hr class="mh-separator content-list-separator"><article class="content-list clearfix post-238 post type-post status-publish format-standard hentry category-v2n1">  <header class="content-list-header"> <p class="entry-meta"> </p> <h3 class="content-list-title"><a href="https://jaddictionscience.com/2016/05/04/off-label-use-of-suboxone-for-treatment-resistant-depression/" title="Off Label Use of Suboxone for Treatment Resistant Depression" rel="bookmark">Off Label Use of Suboxone for Treatment Resistant Depression</a></h3> </header> <div class="content-list-excerpt"> <p><i>George Kamajian, Robert Cable, Jonathan Greco, Brady Laughlin and Tanya deGroot</i><br/> Major Depressive Disorder (MDD) is a condition that affects approximately 12% of the population [1] and recurs at a rate between 50-85% regardless of treatment [2].</p> <a class="button" href="https://jaddictionscience.com/2016/05/04/off-label-use-of-suboxone-for-treatment-resistant-depression/"> <span>Read More</span> </a> </div> </article> <hr class="mh-separator content-list-separator"> </div> <aside class="mh-sidebar"> <div id="search-2" class="sb-widget clearfix widget_search"><form role="search" method="get" class="search-form" action="https://jaddictionscience.com/"> <label> <span class="screen-reader-text">Search for:</span> <input type="search" class="search-field" placeholder="Search …" value="" name="s" title="Search for:"/> </label> <input type="submit" class="search-submit" value="Search"/> </form></div><div id="category-posts-2" class="sb-widget clearfix cat-post-widget"><h4 class="widget-title"><span><a href="">Popular Articles</a></span></h4><ul id="category-posts-2-internal" class="category-posts-internal"> <li class='cat-post-item'><a class="post-title cat-post-title" href="https://jaddictionscience.com/2024/07/10/addiction-co-occurring-with-autism-spectrum-disorder/" rel="bookmark">Addiction Co-occurring with Autism Spectrum Disorder</a> </li><li class='cat-post-item'><a class="post-title cat-post-title" href="https://jaddictionscience.com/2024/05/10/language-matters-a-critical-discourse-analysis-of-how-substance-use-disorders-are-portrayed-in-a-primary-care-journal-over-the-last-20-years/" rel="bookmark">Language Matters: A Critical Discourse Analysis of How Substance Use Disorders are Portrayed in a Primary Care Journal Over the Last 20 Years</a> </li><li class='cat-post-item'><a class="post-title cat-post-title" href="https://jaddictionscience.com/2024/04/02/understanding-the-balancing-students-juggling-work-and-studies-the-digital-dilemma-phone-usage-among-students/" rel="bookmark">Understanding the Balancing: Students Juggling Work and Studies. 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