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10.5596C12.2636 10.5596 12.1176 10.349 12.0783 9.37285H14.4503C14.9976 9.37285 15.2418 9.15664 15.2418 8.67213C15.2418 7.64237 15.0266 6.27171 13.165 6.27171C11.5931 6.27171 10.8919 7.12946 10.8919 9.05247C10.8919 10.9297 11.5452 11.6281 13.3016 11.6281C14.0318 11.6281 14.6097 11.5152 14.8366 11.4111C14.9811 11.3495 15.1138 11.2572 15.1138 11V10.8122C15.113 10.5699 14.9748 10.4239 14.7432 10.4239Z" fill="currentColor"></path><path d="M12.0846 8.41359C12.1301 7.57715 12.4701 7.20312 13.1831 7.20312H13.1838C13.8614 7.20312 14.1661 7.56532 14.1975 8.41202L12.0846 8.41359Z" fill="currentColor"></path><path d="M31.4197 13.2932H25.348L23.7136 18.0002H20.0957L26.4898 0.198242H30.7749L37.0436 18.0002H33.1032L31.4197 13.2932ZM28.4689 3.60924L26.1405 10.5302H30.6719L28.4689 3.60924Z" fill="currentColor"></path><path d="M49.178 18L45.1885 11.925H42.4616V18H38.9421V0.621C38.9421 0.621 41.1944 0 45.2332 0C49.8676 0 52.6393 1.62 52.6393 5.2515C52.6393 8.9595 50.3601 10.5525 48.7258 11.277L53.3826 18H49.178ZM42.466 9.1125H46.4556C48.1661 8.3925 48.9586 7.47 48.9586 5.6025C48.9586 3.6585 47.5706 2.889 45.2914 2.889C43.8541 2.889 42.466 3.1365 42.466 3.1365V9.1125Z" fill="currentColor"></path><path d="M55.4691 17.9996V0.24707H67.5319V3.25757H59.0109V7.71257H66.3677V10.6016H59.0109V14.9846H67.7558V17.9996H55.4691Z" fill="currentColor"></path><path d="M70.3842 17.9996V0.24707H82.4469V3.25757H73.926V7.71257H81.2828V10.6016H73.926V14.9846H82.6708V17.9996H70.3842Z" fill="currentColor"></path><path d="M88.7872 17.9996H85.2947V0.24707H88.5633L97.1111 11.4746V0.24707H100.631V17.9996H97.9798L88.7872 6.20057V17.9996Z" fill="currentColor"></path><path d="M113.831 13.2932H107.759L106.129 18.0002H102.511L108.901 0.198242H113.186L119.455 18.0002H115.514L113.831 13.2932ZM110.884 3.60924L108.556 10.5302H113.087L110.884 3.60924Z" fill="currentColor"></path></svg><p class="_1m3quf82 fck75q2">Sarjat. 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class="aw-1ag6w51 nvljT"><a href="/web/20240205040532/https://yle.fi/t/18-211990/fi" aria-label="Lisää artikkeleita aiheesta Sairaudet" class="aw-l7odld jXfkxq">Sairaudet</a></div><h1 class="sc-aXZVg cZXpWU yle__article__heading yle__article__heading--1">Kouvolassa tutkitaan, löytyisikö psykedeeleistä apua alkoholiriippuvuuteen</h1><p class="aw-1gybjub aw-5vja16 jxdWmn eeXVLF yle__article__paragraph">A-klinikan Kouvolan yksikkö ottaa osaa tutkimukseen, jossa koehenkilöille annetaan sienissäkin esiintyvää psilosybiiniä. </p><div class="aw-e30oo3 blLbha"></div><figure class="aw-u5oz0a clzEhy yle__article__figure"><script type="application/ld+json">{"@id":"74-20068646","@context":"https://web.archive.org/web/20240205040532/https://schema.org","image":{"@type":"ImageObject","description":"Tutkimuksessa käytetään erityispuhdistettua synteettistä psilosybiiniä. 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Kuvituskuva.</span><span> Kuva: Henrietta Hassinen / Yle</span></figcaption></figure><div class="aw-1wk2icm iaIVgA"><div class="aw-qww0lc eFtfQt"><div class="aw-x5rn7a iKNQRH"><span class="aw-z7z0zi hEWAhM">Heikki Koskinen</span></div></div></div><div class="aw-1hwlbbb iumvhG"><div class="aw-64d2lh cPAYLb"><div class="aw-kzjed4 dgiUVP yle__article__date"><time class="aw-lsqctp jPSFYl yle__article__date--published" datetime="2024-01-10T09:56:53+02:00">10.1. 9:56</time><span aria-hidden="true" class="aw-131q90r bsXkQk">•</span><time class="aw-lsqctp jPSFYl yle__article__date--modified" datetime="2024-01-10T10:03:02+02:00">Päivitetty 10.1. 10:03</time></div></div><a href="https://web.archive.org/web/20240205040532/https://yle.onelink.me/46xJ/07zyq6zz?deep_link_sub1=74-20068646" class="aw-pqa0kd GtYAc">Avaa Yle-sovelluksessa<svg width="24" height="24" viewbox="0 0 24 24" fill="none" aria-hidden="true"><path d="M15 2a1 1 0 1 0 0 2h3.586l-9.293 9.293a1 1 0 1 0 1.414 1.414L20 5.414V9a1 1 0 1 0 2 0V3a1 1 0 0 0-1-1h-6ZM5 7a1 1 0 0 0-1 1v11a1 1 0 0 0 1 1h11a1 1 0 0 0 1-1v-6a1 1 0 0 1 2 0v6a3 3 0 0 1-3 3H5a3 3 0 0 1-3-3V8a3 3 0 0 1 3-3h6a1 1 0 1 1 0 2H5Z" fill="currentColor"></path></svg></a><div class="aw-itub5i eehAxh"><div><button aria-label="Jaa artikkeli" aria-disabled="false" id="share-menu-button" aria-haspopup="true" class="Buttonstyles__ButtonBase-sc-17sr1bx-0 Buttonstyles__ButtonText-sc-17sr1bx-3 jrqhnK kvhUhF"><span class="Buttonstyles__iconSize-sc-17sr1bx-4 Buttonstyles__IconWrapper-sc-17sr1bx-6 cazOWd dPcqZv yds-button__icon"><svg width="24" height="24" viewbox="0 0 24 24" fill="none" aria-hidden="true" class="aw-wi5224 fZrvxl"><path fill-rule="evenodd" clip-rule="evenodd" d="M12.43 3.078a1 1 0 0 1 1.087.207l8.182 8a1 1 0 0 1 0 1.43l-8.182 8a1 1 0 0 1-1.7-.715v-3.855h-.008c-1.968.029-3.972.988-5.827 2.417L3.61 20.389a1 1 0 0 1-1.592-.981l.5-2.597.014-.062c.23-.883.58-1.911.986-2.865.4-.94.88-1.876 1.387-2.532.964-1.246 2.07-2.138 3.405-2.709 1.057-.45 2.219-.684 3.508-.76V4a1 1 0 0 1 .612-.922Zm1.388 3.298v3.48h-1c-1.529 0-2.727.202-3.722.627-.984.42-1.826 1.081-2.609 2.093-.351.454-.753 1.206-1.129 2.09a19.46 19.46 0 0 0-.874 2.525l.277-.213c2.023-1.559 4.445-2.798 7.028-2.833h2.029v3.479L19.57 12l-5.752-5.624Z" fill="currentColor"></path></svg></span><span class="Buttonstyles__TextWrapper-sc-17sr1bx-7 WDnuQ yds-button__text">Jaa</span></button></div></div></div></header><section class="yle__article__content"><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">Kouvolan A-klinikka on mukana tutkimuksessa, jossa selvitetään, voisiko psykedeelisistä aineista saada apua alkoholiriippuvuuden hoitoon.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">Tutkimuksessa alkoholiriippuvaisille koehenkilöille annetaan psilosybiiniä, joka on esimerkiksi joissain sienilajeissa esiintyvä psykedeelinen aine. Tutkimuksessa käytetään erityispuhdistettua synteettistä psilosybiiniä.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">– Aine avaa riittävässä määrin porttia ihmisen alitajuntaan, jolloin syvempien tunnetilojen ja traumojen käsittely tulee helpommaksi, sanoo A-klinikka oy:n lääketieteellinen johtaja <strong class="aw-ak79eh hgoSon yle__article__strong">Ulriika Sundell</strong>.</p><figure class="aw-u5oz0a crkERF yle__article__figure"><script type="application/ld+json">{"@id":"74-20068646","@context":"https://web.archive.org/web/20240205040532/https://schema.org","image":{"@type":"ImageObject","description":"Psilosybiiniä esiintyy luonnossa esimerkiksi joissain sienilajeissa. Arkistokuva. ","copyrightHolder":"Lauri Rautavuori / Yle","url":"https://web.archive.org/web/20240205040532/https://images.cdn.yle.fi/image/upload/ar_1.7520278099652375,c_fill,g_faces,h_684,w_1200/dpr_1.0/q_auto:eco/f_auto/fl_lossy/39-943441625e955167152","keywords":"Psilosybiini,Psilosybiinisienet,Suippumadonlakki,Madonlakit,sienet,psykedeelit,huumeet,mielenterveys"}}</script><div class="aw-1a00tic hTjHtb"><div class="aw-1qvmjke bKIcxT"><div class="aw-1njknqq euollB"><picture><source data-testid="source-for-S" srcset="https://web.archive.org/web/20240205040532im_/https://images.cdn.yle.fi/image/upload/ar_1.7520278099652375,c_fill,g_faces,h_684,w_1200/dpr_2.0/q_auto:eco/f_auto/fl_lossy/v1650367669/39-943441625e955167152 2x, https://web.archive.org/web/20240205040532im_/https://images.cdn.yle.fi/image/upload/ar_1.7520278099652375,c_fill,g_faces,h_684,w_1200/dpr_1.0/q_auto:eco/f_auto/fl_lossy/v1650367669/39-943441625e955167152 1x"/><img alt="Etualalla yksittäinen kuivattu suippumadonlakki peukalon ja etusormen välissä, taustalla minigrip-pussi täynnä samoja sieniä." src="https://web.archive.org/web/20240205040532im_/https://images.cdn.yle.fi/image/upload/c_crop,h_1698,w_3020,x_3,y_15/ar_1.7777777777777777,c_fill,g_faces,h_675,w_1200/dpr_1.0/q_auto:eco/f_auto/fl_lossy/v1650367669/39-943441625e955167152" class="aw-1l9m598 bTKagC"/></picture></div><div class="aw-45s348 glxCAO"><button aria-disabled="false" class="Buttonstyles__ButtonBase-sc-17sr1bx-0 Buttonstyles__ButtonSecondary-sc-17sr1bx-2 blJlbw iLYbQX"><span class="Buttonstyles__TextWrapper-sc-17sr1bx-7 kWJvkV yds-button__content">Avaa kuvien katselu</span></button></div></div></div><figcaption class="aw-kr26k0 iEoONW"><span>Psilosybiiniä esiintyy luonnossa esimerkiksi joissain sienilajeissa. Arkistokuva. </span><span> Kuva: Lauri Rautavuori / Yle</span></figcaption></figure><h2 class="sc-gEvEer kGTkjt yle__article__heading yle__article__heading--2">Lääkehoito yhdistetään terapiaan</h2><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">Tutkimuksen aikana osallistujat saavat yhteensä kaksi annosta neljän viikon välein joko psilosybiiniä sisältävän kapselin tai lumekapselin. Tutkimuksen tarkoituksena on selvittää, vähentääkö 25 milligramman psilosybiiniannos terapiaan yhdistettynä henkilöiden alkoholinkäyttöä.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">Tällä hetkellä psilosybiinihoito on vasta tutkimusvaiheessa. Psykedeelisten aineiden käyttöön hoitokeinoina on liittynyt Sundelin mukaan aiemmin paljon ennakkoluuloja. Aineet yhdistetään helposti 1960-luvun nuorison aistiharhakokeiluihin LSD:llä.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">– Psykedeelejä hyödyntävät tutkimukset ovat lisääntyneet viimeisen 10 vuoden aikana maailmalla. Hyviä tuloksia on saatu jo erilaisten psyykkisten tilojen hoidossa, toteaa Sundell.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">Sundelin mukaan psilosybiinin mahdollisilta negatiivisilta vaikutuksilta vältytään, kun annokset pidetään riittävän pieninä.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">A-klinikka etsii parhaillaan vapaaehtoisia osallistumaan Kouvolassa tehtäviin tutkimuksiin. Tutkimukseen soveltuvat ihmiset osallistuvat 8 viikon mittaiseen terapiajaksoon ja 16 viikkoa kestävään seurantajaksoon. Lisätietoja osallistumisen ehdoista <a class="aw-iao6s4 drtaeR yle__article__link" href="https://web.archive.org/web/20240205040532/https://www.a-klinikka.fi/tietoa-meista/tutkimukset-ja-hankkeet/uusi-tutkimuslaake-alkoholiriippuvuuteen" role="link">löytyy täältä</a>.</p><p class="aw-1gybjub aw-1p7kakr jxdWmn ilDxnw yle__article__paragraph">– Kymenlaakso on alueena sellainen, jossa tiedetään olevan paljon alkoholiriippuvuudesta kärsiviä ihmisiä, sanoo Sundell.</p></section><footer class="yle__article__footer"><h2 class="aw-zh6d69 dMYkJU">Aiheesta enemmän: Paketissa 1 linkki</h2><h2 class="sc-eqUAAy ctFUoD yle__article__heading yle__article__heading--3" aria-hidden="true">Aiheesta enemmän</h2><div class="yle__article__links" role="list" aria-label="Aiheesta enemmän"><div role="listitem" class="aw-124ec9l cFgRwb"><div class="aw-yq4wj5 hkKela"><div class="aw-fou4nx hULxUh"><div class="aw-aqrehu kskGQO"><div class="aw-ej1jxx Vjwex"><a 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Tutkimuksessa käytetään erityispuhdistettua synteettistä psilosybiiniä.","type":"text"},{"text":"– Aine avaa riittävässä määrin porttia ihmisen alitajuntaan, jolloin syvempien tunnetilojen ja traumojen käsittely tulee helpommaksi, sanoo A-klinikka oy:n lääketieteellinen johtaja **Ulriika Sundell**.","type":"text"},{"displayStyle":"normal","alt":"Etualalla yksittäinen kuivattu suippumadonlakki peukalon ja etusormen välissä, taustalla minigrip-pussi täynnä samoja sieniä.","source":"Lauri Rautavuori \u002F Yle","aspect":1.7520278099652375,"caption":"Psilosybiiniä esiintyy luonnossa esimerkiksi joissain sienilajeissa. Arkistokuva. ","id":"39-943441625e955167152","type":"image","alts":[{"language":"fin","value":"Etualalla yksittäinen kuivattu suippumadonlakki peukalon ja etusormen välissä, taustalla minigrip-pussi täynnä samoja sieniä."}],"blurhash":"LEG*j7}u9Z4.yrOr-6wJPA0z4-Ri","tags":[{"label":[{"language":"fin","value":"Psilosybiini"},{"language":"swe","value":"psilocybin"}],"extId":"18-276293"},{"label":[{"language":"eng","value":"Magic mushroom"},{"language":"fin","value":"Psilosybiinisienet"},{"language":"swe","value":"psykedeliska svampar"}],"extId":"18-276298"},{"label":[{"language":"fin","value":"Suippumadonlakki"},{"language":"swe","value":"Toppslätskivling"}],"extId":"18-276294"},{"label":[{"language":"eng","value":"Psilocybe"},{"language":"fin","value":"Madonlakit"},{"language":"rus","value":"Псилоцибе"},{"language":"swe","value":"Slätskivlingar"}],"extId":"18-336773"},{"label":[{"language":"fin","value":"sienet"},{"language":"swe","value":"svampar"}],"extId":"18-214613"},{"label":[{"language":"fin","value":"psykedeelit"},{"language":"swe","value":"psykedeliska droger"}],"extId":"18-276297"},{"label":[{"language":"fin","value":"huumeet"},{"language":"swe","value":"narkotika"}],"extId":"18-210070"},{"label":[{"language":"fin","value":"mielenterveys"},{"language":"swe","value":"mental hälsa"}],"extId":"18-205088"}],"copyright":[{"language":"und","value":"Lauri Rautavuori \u002F Yle"}],"crops":[{"name":"16:9","aspect":1.78,"coordinates":{"x":3,"y":15,"width":3020,"height":1698}},{"name":"2:3","aspect":0.67,"coordinates":{"x":914,"y":0,"width":1150,"height":1726}},{"name":"1:1","aspect":1,"coordinates":{"x":636,"y":0,"width":1726,"height":1726}},{"name":"5:2","aspect":2.5,"coordinates":{"x":3,"y":290,"width":3020,"height":1208}}],"height":1726,"licence":{"id":"6","name":[{"language":"und","value":"Yle"}],"properties":[]},"version":"1650367669","width":3024,"recommendedFormat":"jpg"},{"text":"Lääkehoito yhdistetään terapiaan","level":2,"type":"heading"},{"text":"Tutkimuksen aikana osallistujat saavat yhteensä kaksi annosta neljän viikon välein joko psilosybiiniä sisältävän kapselin tai lumekapselin. Tutkimuksen tarkoituksena on selvittää, vähentääkö 25 milligramman psilosybiiniannos terapiaan yhdistettynä henkilöiden alkoholinkäyttöä.","type":"text"},{"text":"Tällä hetkellä psilosybiinihoito on vasta tutkimusvaiheessa. Psykedeelisten aineiden käyttöön hoitokeinoina on liittynyt Sundelin mukaan aiemmin paljon ennakkoluuloja. Aineet yhdistetään helposti 1960-luvun nuorison aistiharhakokeiluihin LSD:llä.","type":"text"},{"text":"– Psykedeelejä hyödyntävät tutkimukset ovat lisääntyneet viimeisen 10 vuoden aikana maailmalla. Hyviä tuloksia on saatu jo erilaisten psyykkisten tilojen hoidossa, toteaa Sundell.","type":"text"},{"text":"Sundelin mukaan psilosybiinin mahdollisilta negatiivisilta vaikutuksilta vältytään, kun annokset pidetään riittävän pieninä.","type":"text"},{"text":"A-klinikka etsii parhaillaan vapaaehtoisia osallistumaan Kouvolassa tehtäviin tutkimuksiin. Tutkimukseen soveltuvat ihmiset osallistuvat 8 viikon mittaiseen terapiajaksoon ja 16 viikkoa kestävään seurantajaksoon. Lisätietoja osallistumisen ehdoista [löytyy täältä](https:\u002F\u002Fwww.a-klinikka.fi\u002Ftietoa-meista\u002Ftutkimukset-ja-hankkeet\u002Fuusi-tutkimuslaake-alkoholiriippuvuuteen).","type":"text"},{"text":"– Kymenlaakso on alueena sellainen, jossa tiedetään olevan paljon alkoholiriippuvuudesta kärsiviä ihmisiä, sanoo Sundell.","type":"text"},{"type":"links","links":[{"external":{"url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20240205040532\u002Fhttps:\u002F\u002Fyle.fi\u002Fa\u002F74-20004397"},"internal":{"id":"74-20004397"},"title":"Sienitrippi voi olla niin voimakas, että ihminen lopettaa juomisen – Suomessa aletaan ensimmäistä kertaa tutkia psykedeelejä ihmiskokeilla","datePublished":"2022-11-13T10:46:22+0200","subject":{"description":{"fi":"soveltavat tieteet","sv":"tillämpade vetenskaper","en":"","ru":null,"se":null},"exactMatch":["finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fmesh\u002FD008511","leiki:focus100k_na_2212","freebase:\u002Fm\u002F04sh3","wikidata:Q11190","finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp35901"],"updated":"2016-09-22T13:15:31+03:00","alternativeIds":["18-292","18-37038","18-144610","18-11565","18-16722"],"title":{"fi":"lääketiede","sv":"medicin","en":null,"ru":null,"se":null},"types":["Concept"],"id":"18-219402","contentHits":2662},"headline":{"image":{"aspect":1.3333333333333333,"alt":"Kasa psykedeelisiä psilosybiinisieniä puisella alustalla.","caption":"Psilosybiini on tietyissä sienilajeissa esiintyvä alkaloidi, joka vaikuttaa voimakkaasti ihmisen tietoisuuteen. Arkistokuva.","source":"Lauri Rautavuori \u002F Yle","id":"39-1033013636e40385d9b8","type":"image"},"full":"Sienitrippi voi olla niin voimakas, että ihminen lopettaa juomisen – Suomessa aletaan ensimmäistä kertaa tutkia psykedeelejä ihmiskokeilla"}}]}],"subjects":[{"description":{"fi":"biologiset ilmiöt","sv":"biologiska fenomen","en":"illness","ru":null,"se":null},"exactMatch":["leiki:focus100k_na_1094981","leiki:focus100k_na_1447961","freebase:\u002Fm\u002F027x3","finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp16845","wikidata:Q12136"],"updated":"2022-10-02T21:12:59+03:00","alternativeIds":["18-1133","18-23238","18-291200","18-323040","18-130903"],"title":{"fi":"sairaudet","sv":"sjukdomar","en":"sickness","ru":null,"se":null},"types":["MainConcept","Concept"],"id":"18-211990","contentHits":1254},{"description":{"fi":"tutkimustoiminta","sv":"forskningsverksamhet","en":"","ru":null,"se":null},"exactMatch":["leiki:focus100k_na_4048","freebase:\u002Fm\u002F06cs1","wikidata:Q42240","finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp36376"],"updated":"2022-10-02T21:24:33+03:00","alternativeIds":["18-146495","18-204805","18-211346","18-22691","18-369","18-37453"],"title":{"fi":"tutkimus","sv":"forskning","en":null,"ru":null,"se":null},"types":["MainConcept","Concept"],"id":"18-214216","contentHits":8304},{"description":{"fi":"Suomen kaupunki, joka sijaitsee Kymijoen varrella Kymenlaakson maakunnassa. Kouvola perustettiin kauppalaksi vuonna 1922, ja vuonna 1960 Kouvolasta tuli yksi Suomen kuudesta ensimmäisestä uudesta kaupungista. Nykyinen Kouvolan kaupunki muodostui 1. tammikuuta 2009, kun Kouvolan, Anjalankosken ja Kuusankosken kaupungit, Elimäki, Jaala ja Valkeala yhdistyivät.\nKaupungissa asuu 85 861 ihmistä.\n\n","sv":"stad i landskapet Kymmenedalen i Finland. Staden är belägen cirka 132 kilometer nordost om Helsingfors och cirka 50 kilometer norr om Kotka. Folkmängden i Kouvola stad uppgår till cirka 85 979 invånare.\nStaden gränsar till följande städer och kommuner: Fredrikshamn, Heinola, Itis, Kotka, Lappträsk, Lovisa, Luumäki, Miehikkälä, Mäntyharju, Pyttis och Savitaipale.\nKouvola stad ingår i Kouvola ekonomiska region.\nKouvola stads språkliga status är enspråkig finsk.","en":null,"ru":null,"se":null},"exactMatch":["leiki:focus100k_na_1926","freebase:\u002Fm\u002F021tgg","leiki:focus100k_na_230622","wikidata:Q33686361","leiki:focus100k_na_635253","wikidata:Q204382"],"updated":"2020-11-17T10:25:21+02:00","alternativeIds":["18-147400","18-35001","18-56970","18-17789","18-91685","18-305041"],"title":{"fi":"Kouvola","sv":"Kouvola","en":null,"ru":null,"se":null},"types":["Concept","Place"],"id":"18-180134","contentHits":11306},{"description":{"fi":"aine","sv":"rusmedel","en":"","ru":null,"se":null},"exactMatch":["finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp14860","leiki:focus100k_na_3154","wikidata:Q3706669","freebase:\u002Fm\u002F0m1vx"],"updated":"2022-10-02T21:00:38+03:00","alternativeIds":["18-36051","18-1208","18-33538","18-210873","18-150038"],"title":{"fi":"päihteet","sv":"droger och alkohol","en":null,"ru":null,"se":null},"types":["MainConcept","Concept"],"id":"18-211104","contentHits":5145},{"description":{"fi":"aine","sv":"materia","en":"","ru":null,"se":null},"exactMatch":["wikidata:Q12140","finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp34822","freebase:\u002Fm\u002F018l35","leiki:focus100k_na_28915"],"updated":"2023-01-27T13:49:25+02:00","alternativeIds":["18-37105","18-31","18-209549","18-25740","18-131378","18-211900"],"title":{"fi":"lääkkeet","sv":"mediciner","en":"medicines","ru":null,"se":null},"types":["MainConcept","Concept"],"id":"18-214540","contentHits":4290},{"description":{"fi":"riippuvuus","sv":"beroende","en":"Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use. A drug addiction, a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An addictive drug is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral addiction and drug addictions, but not dependence.\nWithin the framework of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders, substance dependence is redefined as a drug addiction, and can be diagnosed without the occurrence of a withdrawal syndrome. It is now described accordingly:\nWhen an individual persists in use of alcohol or other drugs despite problems related to use of the substance, substance dependence may be diag","ru":null,"se":null},"exactMatch":["wikidata:Q182413","freebase:\u002Fm\u002F0466pc0","finto:http:\u002F\u002Fwww.yso.fi\u002Fonto\u002Fkoko\u002Fp69520","leiki:focus100k_na_3153"],"updated":"2019-12-04T16:42:11+02:00","alternativeIds":["18-20678","18-19587","18-39831","18-134273"],"title":{"fi":"päihderiippuvuus","sv":"rusmedelsberoende","en":"Substance dependence","ru":null,"se":null},"types":["Concept"],"id":"18-215602","contentHits":1061},{"description":{"fi":"Kymenlaakson maakunta (ruots. Kymmenedalen) on Suomen maakunta Kaakkois-Suomessa. Maakunnan nimi johtuu sen halki kulkevasta Kymijoesta, jonka varrella tai lähellä sitä ovat seudun suurimmat asutuskeskukset. Kymenlaakson maakuntakeskukset ovat Kotka ja Kouvola. Kotkassa sijaitsevat muun muassa maakunnan liiton hallinto, keskussairaala ja maakuntamuseo, Kouvolassa puolestaan maakuntakirjasto ja maakunnan suurin rautatieasema. Kouvola on ollut maakunnan suurin kaupunki vuonna 2009 tapahtuneiden kuntaliitosten jälkeen 87 964 asukkaalla. Maakunnan suurin kaupunkialue sen sijaan on Kotkan keskustaajama 53 206 asukkaalla.\nKymenlaakso oli Suomen ensimmäisiä laajasti teollistuneita alueita, jo 1800-luvulta alkaen. Teollisuus keskittyi Voikkaan ja Kotkan välisen rautatien varteen. Nykyään alue kärsii raskaan teollisuuden, pääosin paperiteollisuuden, taantumisesta, kun korvaavaa työllistäjää ei ole löytynyt. Taantumisen seurauksena alueella on muuttotappio pääosin Helsingin seudulle. Silti alueelle muuttaa väkeä jopa ulkomailta, etupäässä Venäjältä. Bruttokansantuote Kymenlaaksossa oli vuonna 2001 yhteensä 4 147 miljoonaa euroa.\nKymenlaakson maakuntaa ympäröivät Uusimaa lounaassa, Päijät-Häme luoteessa, Etelä-Savo pohjoisessa ja Etelä-Karjala idässä.","sv":"Kymmenedalen (finska: Kymenlaakso) är ett landskap i forna Södra Finlands län i Finland. Landskapet har uppstått längs Kymmene älv, som i söder mynnar ut i Finska viken vid landskapets huvudort, staden Kotka. Kymmenedalen består av sju kommuner.\nFolkmängden i Kymmenedalen uppgick den 31 december 2012 till 181 421 invånare, landskapets totala areal utgjordes den 1 januari 2012 av 7 455,52 kvadratkilometer, och därav utgjordes landytan av 5 147,78 km² . Vid årsskiftet 2012\u002F2013 var befolkningstätheten i Kymmenedalen 35,24 invånare per kvadratkilometer.","en":"","ru":null,"se":null},"exactMatch":["freebase:\u002Fm\u002F03b_t8","wikidata:Q5698","leiki:focus100k_na_63222"],"updated":"2016-09-22T13:48:30+03:00","alternativeIds":["18-131408","18-22613","18-85355"],"title":{"fi":"Kymenlaakso","sv":"Kymmenedalen","en":null,"ru":null,"se":null},"types":["Concept","Place"],"id":"18-198551","contentHits":13180},{"description":{"fi":"Psykedeelit ovat yhdisteitä, jotka aiheuttavat muuntuneita tajunnantiloja kuten aistiharhoja, mystisiä kokemuksia, mielleyhtymiä, voimakkaita tunnetiloja ja muistojen nousemista pintaan. Ne toimivat hermovälittäjäaineiden tapaan ja aktivoivat hermosolujen pinnalla olevia reseptoreja.\nTunnetuimpia psykedeelejä ovat esimerkiksi LSD, psilosiini, meskaliini, LSA ja DMT. Useimpien psykedeelien käyttö on kiellettyä suuressa osassa maailmaa, pois lukien luvanvarainen käyttö esimerkiksi uskonnollisissa seremonioissa, terapiassa tai tieteellisessä tutkimuksessa. Lääketieteessä psykedeelejä on käytetty esimerkiksi riippuvuuksien hoitokeinona.\nPsykedeelit määritellään farmakologisesti usein osaksi laajempaa hallusinogeenien ryhmää, johon kuuluvat myös dissosiatiivit ja deliriantit.","sv":"Psykedelia (även psykedelika) är ett samlingsnamn för en stor grupp psykoaktiva droger med liknande effekter. Här ingår LSD, psilocybin och meskalin, tillsammans med en stor mängd andra växter och kemikalier, till exempel cannabis, DMT och 2C-B. \nAlla psykedeliska upplevelser har inte alltid att göra med hallucinationer. Ordet hallucinogen är därför ofta inte adekvat för att beskriva effekterna av vissa psykedeliska droger då hallucinationer inte alltid är en effekt, vad som istället kan upplevas är ofta att sinnesintrycken kraftigt förstärks. Förstärkta sinnesintryck kan ge upphov till hallucinationer när hjärnan försöker tolka en större mängd information som vi inte är vana vid, hjärnan använder sig då av referenser bland minnen och föreställningar för att ge tydlighet åt det du upplever. Förstärka sinnesintryck kan innebära att man under en viss tid ser, hör, känner och luktar bättre och exempelvis så kan man uppfatta färger starkare än vanligt och synskärpan kan ökas drastiskt. När man har en psykedelisk upplevelse så kan även sinnesintrycken förväxlas och förvirra, detta kallas för synestesi och kan ge upphov till hallucinationer som att man kan se ljud eller känna smaken av färg.\nNågra typiska psykedeliska effekter är syn- och hörselförändringar, hallucinationer, sammanblandning av sinnena, starka skönhetsupplevelser, upplösning av jaget och en känsla av enhet, religiösa upplevelser och konfrontationer med det undermedvetna. 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