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KEGG ENZYME: 4.1.2.64
<!doctype html> <html><head> <title>KEGG ENZYME: 4.1.2.64</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1743931015"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1743931015"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1743931015" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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} } } function Link_XtrctSeq2(form) { var dna_from; var dna_to; var dna_len; var plus_up = Number(form.XtrctSeq_UP.value) ; var plus_down = Number(form.XtrctSeq_DOWN.value); var vector = Number(form.VECTOR.value); var org = form.ORG.value; var chr = form.CHR.value; var kid = form.KEGGID.value; var url; if (plus_up == 0 && plus_down == 0) { url = "/entry/-f+-n+n+" + kid; } else { if (vector == 1) { dna_from = Number(form.FROM.value) - plus_up; dna_to = Number(form.TO.value) + plus_down; } else { dna_from = Number(form.FROM.value) - plus_down; dna_to = Number(form.TO.value) + plus_up; } url = "/dbget-bin/cut_sequence_genes.pl?FROM=" + dna_from + "&TO=" + dna_to +"&VECTOR=" + vector + "&ORG=" + org; if (chr) url += "&CHR=" + chr; } //window.open( url, "_self" ); location.href = url; } function go_taxonomy(form,params){ for(var key in params){ if(form[key]){ form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="683"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg2.gif"></a></td><td> </td><td><a name="enzyme:4.1.2.64"></a><font class="title2">ENZYME: 4.1.2.64</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_enzyme.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/kegg-bin/search_htext" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">EC 4.1.2.64 Enzyme <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">2-dehydro-3-deoxy-L-fuconate aldolase;<br> 2-keto-3-deoxy-L-fuconate aldolase;<br> L-2-keto-3-deoxyfuconate aldolase;<br> fucH (gene name)<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Class</span></th> <td class="td20 defd"><div class="cel">Lyases;<br> Carbon-carbon lyases;<br> Aldehyde-lyases<br> <button class="btn" onclick="location.href='/brite/ko01000+4.1.2.64';return false;">BRITE hierarchy</button></div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Sysname</span></th> <td class="td21 defd"><div class="cel">2-dehydro-3-deoxy-L-fuconate (S)-lactaldehyde-lyase (pyruvate-forming)<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Reaction(IUBMB)</span></th> <td class="td20 defd"><div class="cel">2-dehydro-3-deoxy-L-fuconate = pyruvate + (S)-lactaldehyde [RN:<a href="/entry/R13181">R13181</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction(KEGG)</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R13181">R13181</a><br> <button class="btn" onclick="location.href='/entry/R13181';return false;">Reaction</button></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Substrate</span></th> <td class="td20 defd"><div class="cel">2-dehydro-3-deoxy-L-fuconate [CPD:<a href="/entry/C03827">C03827</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Product</span></th> <td class="td21 defd"><div class="cel"><div class="cel">pyruvate [CPD:<a href="/entry/C00022">C00022</a>];<br> (S)-lactaldehyde [CPD:<a href="/entry/C00424">C00424</a>]<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Comment</span></th> <td class="td20 defd"><div class="cel">The enzyme, characterized from the bacteria Veillonella ratti and Campylobacter jejuni, participates in an L-fucose degradation pathway. It also has significant activity with 2-dehydro-3-deoxy-D-pentonate (cf. EC <a href="/entry/4.1.2.28">4.1.2.28</a>, 2-dehydro-3-deoxy-D-pentonate aldolase).<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">History</span></th> <td class="td21 defd"><div class="cel">EC 4.1.2.64 created 2023<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/ec00051+4.1.2.64">ec00051</a> </span></td><td>Fructose and mannose metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/ec01100+4.1.2.64">ec01100</a> </span></td><td>Metabolic pathways</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/ec01120+4.1.2.64">ec01120</a> </span></td><td>Microbial metabolism in diverse environments</td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Orthology</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/K26911">K26911</a> </span></td><td>2-dehydro-3-deoxy-L-fuconate aldolase</td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Genes</span></th> <td class="td20 defd"><style>span.g1a{color:#003399}span.g1a:hover{color:#33cc99;cursor:pointer;}div.g1{display:none;}</style><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g11">LGB</span>: </span></td><td id="g11d">V8L73_08505</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g12">AMAX</span>: </span></td><td id="g12d">ABWH92_01285</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g13">CJE</span>: </span></td><td id="g13d">Cj0481(dapA)</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g14">CJB</span>: </span></td><td id="g14d">BN148_0481(dapA)</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g15">CJI</span>: </span></td><td id="g15d">CJSA_0451(dapA)</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g16">CJS</span>: </span></td><td id="g16d">CJS3_0473</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g17">CJP</span>: </span></td><td id="g17d">A911_02350</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g18">CJEJ</span>: </span></td><td id="g18d">N564_00468</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g19">CJEU</span>: </span></td><td id="g19d">N565_00517</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g110">CJEN</span>: </span></td><td id="g110d">N755_00516</td></tr></table><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g111">CJEI</span>: </span></td><td id="g111d">N135_00533</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g112">CJER</span>: </span></td><td id="g112d">H730_02985</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g113">CJY</span>: </span></td><td id="g113d">QZ67_00492</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g114">CJQ</span>: </span></td><td id="g114d">UC78_0467(dapA_1)</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g115">CJW</span>: </span></td><td id="g115d">PJ18_02395</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g116">CJR</span>: </span></td><td id="g116d">CJE0532</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g117">CJD</span>: </span></td><td id="g117d">JJD26997_1453</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g118">CJZ</span>: </span></td><td id="g118d">M635_06765</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g119">CCC</span>: </span></td><td id="g119d">G157_06235</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g120">CCF</span>: </span></td><td id="g120d">YSQ_07435</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g121">CCY</span>: </span></td><td id="g121d">YSS_02220</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g122">CCOI</span>: </span></td><td id="g122d">YSU_06445</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g123">CCOF</span>: </span></td><td id="g123d">VC76_02535(dapA_1)</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g124">CCOO</span>: </span></td><td id="g124d">ATE51_03242(dapA_2)</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g125">CIS</span>: </span></td><td id="g125d">CINS_1514</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g126">PTHE</span>: </span></td><td id="g126d">LF599_00150 LF599_16950</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g127">LACH</span>: </span></td><td id="g127d">LDX54_02485</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g128">PUF</span>: </span></td><td id="g128d">UFO1_3478</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g129">PFT</span>: </span></td><td id="g129d">JBW_00806</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g130">SACV</span>: </span></td><td id="g130d">SPACI_005250(yjhH_2)</td></tr></table></div><a href="javascript:void(0)" onclick="javascript:toggleField(this,"g1","show all","hide")"> » show all</a><br> <script>for(var i=1;i<=30;i++){if(document.getElementById('g1'+i)){document.getElementById('g1'+i).onclick = function(e){geg1(this,e);};}}function geg1(bobj){var id = bobj.id;var ab = document.getElementById(id).innerText;var dt = document.getElementById(id+'d');var st = dt.innerText.replace(/\([^\)]+\)/g,'').replace(/ /g,'+');var gt = '/entry/'+ab+'+'+st;location.href = gt;}</script><input type="hidden" name="query" form="form1" value="LGB AMAX CJE CJB CJI CJS CJP CJEJ CJEU CJEN CJEI CJER CJY CJQ CJW CJR CJD CJZ CCC CCF CCY CCOI CCOF CCOO CIS PTHE LACH PUF PFT SACV"><input type="hidden" name="htext" form="form1" value="br08601.keg"><input type="hidden" name="option" form="form1" value="-a"><button class="btn" onclick="javascript:go_taxonomy(document.form1,{"action":"/kegg-bin/search_htext"});return false;">Taxonomy</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reference</span></th> <td class="td21 defd"><div class="cel">1 [PMID:<a href="https://www.ncbi.nlm.nih.gov/pubmed/31914410">31914410</a>]</div></td></tr> <tr><th class="th20 rept tal vtop"><span class="nowrap"> Authors</span></th> <td class="td20 repd"><div class="cel">Watanabe S.</div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Title</span></th> <td class="td21 repd"><div class="cel">Characterization of l-2-keto-3-deoxyfuconate aldolases in a nonphosphorylating l-fucose metabolism pathway in anaerobic bacteria.</div></td></tr> <tr><th class="th20 rept tal vtop"><span class="nowrap"> Journal</span></th> <td class="td20 repd"><div class="cel">J Biol Chem 295:1338-1349 (2020)<br>DOI:<a href="https://doi.org/10.1074/jbc.RA119.011854">10.1074/jbc.RA119.011854</a></div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Sequence</span></th> <td class="td21 repd"><div class="cel">[ag:<a href="/entry/ag:WP_127057788">WP_127057788</a>] [cje:<a href="/entry/cje:Cj0481">Cj0481</a>]</div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExplorEnz - The Enzyme Database: </span></td><td><a href="https://www.enzyme-database.org/query.php?ec=4.1.2.64">4.1.2.64</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">IUBMB Enzyme Nomenclature: </span></td><td><a href="https://iubmb.qmul.ac.uk/enzyme/EC4/1/2/64.html">4.1.2.64</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExPASy - ENZYME nomenclature database: </span></td><td><a href="https://enzyme.expasy.org/EC/4.1.2.64">4.1.2.64</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">BRENDA, the Enzyme Database: </span></td><td><a href="https://www.brenda-enzymes.info/enzyme.php?ecno=4.1.2.64">4.1.2.64</a></td></tr></table></td></tr> <tr><th class="th21 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td21 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?enzyme+4.1.2.64';return false;">All DBs</button></td></tr> </table></td></tr></table> <br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>