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class="label">Followers</p><p class="data">8</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">6</p></div></a><a><div class="stat-container js-profile-coauthors" data-broccoli-component="user-info.coauthors-count" data-click-track="profile-expand-user-info-coauthors"><p class="label">Co-authors</p><p class="data">6</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36210205" href="https://www.academia.edu/Documents/in/Learning_Difficulties"><div 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class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by A. Troster</h3></div><div class="js-work-strip profile--work_container" data-work-id="100112187"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112187/Mild_cognitive_impairment_as_a_risk_factor_for_Parkinsons_disease_dementia"><img alt="Research paper thumbnail of Mild cognitive impairment as a risk factor for Parkinson's disease dementia" class="work-thumbnail" src="https://attachments.academia-assets.com/101022831/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112187/Mild_cognitive_impairment_as_a_risk_factor_for_Parkinsons_disease_dementia">Mild cognitive impairment as a risk factor for Parkinson's disease dementia</a></div><div class="wp-workCard_item"><span>Movement disorders : official journal of the Movement Disorder Society</span><span>, Jan 12, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The International Parkinson and Movement Disorder Society criteria for mild cognitive impairment ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The International Parkinson and Movement Disorder Society criteria for mild cognitive impairment in PD were recently formulated. The aim of this international study was to evaluate the predictive validity of the comprehensive (level II) version of these criteria by assessment of their contribution to the hazard of PD dementia. Individual patient data were selected from four separate studies on cognition in PD that provided information on demographics, motor examination, depression, neuropsychological examination suitable for application of level II criteria, and longitudinal follow-up for conversion to dementia. Survival analysis evaluated the predictive value of level II criteria for cognitive decline toward dementia as expressed by the relative hazard of dementia. A total of 467 patients were included. The analyses showed a clear contribution of impairment according to level II mild cognitive impairment criteria, age, and severity of PD motor symptoms to the hazard of dementia. Th...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="30f32b47ca947b7a1f6d3617d3f3f558" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022831,"asset_id":100112187,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022831/download_file?st=MTczMzI2NzE0OCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112187"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112187"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112187; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112187]").text(description); $(".js-view-count[data-work-id=100112187]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112187; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112187']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112187, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "30f32b47ca947b7a1f6d3617d3f3f558" } } $('.js-work-strip[data-work-id=100112187]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112187,"title":"Mild cognitive impairment as a risk factor for Parkinson's disease dementia","translated_title":"","metadata":{"abstract":"The International Parkinson and Movement Disorder Society criteria for mild cognitive impairment in PD were recently formulated. 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The Liverpool Seizure Severity Scale and 31-item Quality of Life in Epilepsy measure showed statistically significant impro...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2ceb003fc90d5dfc4ffc6a618d74b722" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022911,"asset_id":100112184,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022911/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112184"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112184"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112184; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112184]").text(description); $(".js-view-count[data-work-id=100112184]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112184; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112184']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112184, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2ceb003fc90d5dfc4ffc6a618d74b722" } } $('.js-work-strip[data-work-id=100112184]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112184,"title":"Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy","translated_title":"","metadata":{"abstract":"To report long-term efficacy and safety results of the SANTE trial investigating deep brain stimulation of the anterior nucleus of the thalamus (ANT) for treatment of localization-related epilepsy. 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The Liverpool Seizure Severity Scale and 31-item Quality of Life in Epilepsy measure showed statistically significant impro...","publication_date":{"day":6,"month":1,"year":2015,"errors":{}},"publication_name":"Neurology"},"translated_abstract":"To report long-term efficacy and safety results of the SANTE trial investigating deep brain stimulation of the anterior nucleus of the thalamus (ANT) for treatment of localization-related epilepsy. This long-term follow-up is a continuation of a previously reported trial of 5- vs 0-V ANT stimulation. Long-term follow-up began 13 months after device implantation with stimulation parameters adjusted at the investigators\u0026#39; discretion. Seizure frequency was determined using daily seizure diaries. The median percent seizure reduction from baseline at 1 year was 41%, and 69% at 5 years. The responder rate (≥50% reduction in seizure frequency) at 1 year was 43%, and 68% at 5 years. In the 5 years of follow-up, 16% of subjects were seizure-free for at least 6 months. There were no reported unanticipated adverse device effects or symptomatic intracranial hemorrhages. The Liverpool Seizure Severity Scale and 31-item Quality of Life in Epilepsy measure showed statistically significant impro...","internal_url":"https://www.academia.edu/100112184/Long_term_efficacy_and_safety_of_thalamic_stimulation_for_drug_resistant_partial_epilepsy","translated_internal_url":"","created_at":"2023-04-12T11:05:52.399-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022911,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022911/thumbnails/1.jpg","file_name":"a349460a8fbd456a399ef15d98132ea1b475.pdf","download_url":"https://www.academia.edu/attachments/101022911/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Long_term_efficacy_and_safety_of_thalami.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022911/a349460a8fbd456a399ef15d98132ea1b475-libre.pdf?1681332241=\u0026response-content-disposition=attachment%3B+filename%3DLong_term_efficacy_and_safety_of_thalami.pdf\u0026Expires=1733270749\u0026Signature=BTVcDqclkJQZbRHa66u3bHhAB~VroB6OjJW6QKCE2FsSUtb0pcQznZp~PjL6d3fDeTcU0Kvb-0sBvv9Ar~ZBUGLqD7O7x9pGRRWGc4GGs4XrxsSa8mQA-RhVJCYTmaNIabBeIBu6OfuiOevHYMAtujb1v6lGwSPzoYQ7ELWN9OD8uhRztP-kBrEb25fowT2AWH-Z6qpHqKO-bjokJ7ygxWzwWlfR0DzxO5Eyp0No~R7sla2DiXpnI5Hw2npih4mDkZRnwjJnypgyt8jcLmiJrG1VtfGqDBpyaziBpjYw25Rsi8P2GRxGbcd8Jv8WjdacKsK7vNWVhAuoUIE72yV5Vw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Long_term_efficacy_and_safety_of_thalamic_stimulation_for_drug_resistant_partial_epilepsy","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112183"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112183/Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease"><img alt="Research paper thumbnail of Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease" class="work-thumbnail" src="https://attachments.academia-assets.com/101022848/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112183/Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease">Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease</a></div><div class="wp-workCard_item"><span>The Clinical Neuropsychologist</span><span>, 2006</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="729e7c915ff47ad0e6563c639204c30a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022848,"asset_id":100112183,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022848/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112183"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112183"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112183; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "729e7c915ff47ad0e6563c639204c30a" } } $('.js-work-strip[data-work-id=100112183]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112183,"title":"Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease","translated_title":"","metadata":{"publisher":"Informa UK Limited","ai_title_tag":"Statistical Power in STN DBS Cognition Studies for Parkinson's Disease","grobid_abstract":"It has been argued that neuropsychological studies generally possess adequate statistical power to detect large effect sizes. However, low statistical power is problematic in neuropsychological research involving clinical populations and novel interventions for which available sample sizes are often limited. One notable example of this problem is evident in the literature regarding the cognitive sequelae of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in persons with Parkinson's disease (PD). In the current review, a post hoc estimate of the statistical power of 30 studies examining cognitive effects of STN DBS in PD revealed adequate power to detect substantial cognitive declines (i.e., very large effect sizes), but surprisingly low estimated power to detect cognitive changes associated with conventionally small, medium, and large effect sizes. Such wide spread Type II error risk in the STN DBS cognitive outcomes literature may affect the clinical decisionmaking process as concerns the possible risk of postsurgical cognitive morbidity, as well as conceptual inferences to be drawn regarding the role of the STN in higher-level cognitive functions. Statistical and methodological recommendations (e.g., meta-analysis) are offered to enhance the power of current and future studies examining the neuropsychological sequelae of STN DBS in PD.","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"The Clinical Neuropsychologist","grobid_abstract_attachment_id":101022848},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112183/Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease","translated_internal_url":"","created_at":"2023-04-12T11:05:52.223-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022848,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022848/thumbnails/1.jpg","file_name":"2Parsons_TCN_Woods_STNPower_06.pdf","download_url":"https://www.academia.edu/attachments/101022848/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Statistical_Power_of_Studies_Examining_t.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022848/2Parsons_TCN_Woods_STNPower_06-libre.pdf?1681332254=\u0026response-content-disposition=attachment%3B+filename%3DStatistical_Power_of_Studies_Examining_t.pdf\u0026Expires=1733270749\u0026Signature=BFCXJI5lPCQUD7Qe-~QpT2N22N9p2vSU9jQos8LgcaOaF-xmILKTLOengBsDNF-V5r4dmY7f6SCWsgC3xmHofhl7Tt79~9KG8i7OA0bB7I3TgrNlfLWmM0vTdAyugK79myhcN3rvl64V9mpIRgEabYIAwYQ5tFNsTKT7J9xo6xDmcFPQfl6~255lWDGJWRYRFW3CzcbZxaure47tT6IPPyuM7Loo3D4WS2UVoizZJcM3hftvRlUy3O-VOwnVW0PtFqFkTsdU0BhJbsuWxVaoe3Xqf5w0jY8uY1qyX0Ng1hMjOW9ukCcht9xQ9p1auuvrAGl-sBohOWXkkE1blMTbEA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112182"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration"><img alt="Research paper thumbnail of Criteria for the diagnosis of corticobasal degeneration" class="work-thumbnail" src="https://attachments.academia-assets.com/101022844/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration">Criteria for the diagnosis of corticobasal degeneration</a></div><div class="wp-workCard_item"><span>Neurology</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ca55d27efe5ca6ef574d7e4c82e24f45" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022844,"asset_id":100112182,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022844/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112182"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112182"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112182; 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An international consortium of behavioral neurology, neuropsychology, and movement disorders specialists developed new criteria based on consensus and a systematic literature review. Clinical diagnoses (early or late) were identified for 267 nonoverlapping pathologically confirmed CBD cases from published reports and brain banks. Combined with consensus, 4 CBD phenotypes emerged: corticobasal syndrome (CBS), frontal behavioral-spatial syndrome (FBS), nonfluent/agrammatic variant of primary progressive aphasia (naPPA), and progressive supranuclear palsy syndrome (PSPS). Clinical features of CBD cases were extracted from descriptions of 209 brain bank and published patients, providing a comprehensive description of CBD and correcting common misconceptions. Clinical CBD phenotypes and features were combined to create 2 sets of criteria: more specific clinical research criteria for probable CBD and broader criteria for possible CBD that are more inclusive but have a higher chance to detect other tau-based pathologies. Probable CBD criteria require insidious onset and gradual progression for at least 1 year, age at onset $50 years, no similar family history or known tau mutations, and a clinical phenotype of probable CBS or either FBS or naPPA with at least 1 CBS feature. The possible CBD category uses similar criteria but has no restrictions on age or family history, allows tau mutations, permits less rigorous phenotype fulfillment, and includes a PSPS phenotype. Future validation and refinement of the proposed criteria are needed. Neurology â 2013;80:496-503 GLOSSARY AD 5 Alzheimer disease; AOS 5 apraxia of speech; CBD 5 corticobasal degeneration; CBS 5 corticobasal syndrome; CJD 5 Creutzfeldt-Jakob disease; cr-CBD 5 clinical research criteria for probable corticobasal degeneration; DLB 5 dementia with Lewy bodies; FTD 5 frontotemporal dementia; FTLD-TDP 5 frontotemporal lobar degeneration with TDP-43 immunoreactive inclusions; GRN 5 granulin; p-CBD 5 possible corticobasal degeneration criteria; PD 5 Parkinson disease; PNFA 5 progressive nonfluent aphasia; PPA 5 primary progressive aphasia; PSP 5 progressive supranuclear palsy; PSPS 5 progressive supranuclear palsy syndrome.","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"Neurology","grobid_abstract_attachment_id":101022844},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration","translated_internal_url":"","created_at":"2023-04-12T11:05:52.050-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022844,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022844/thumbnails/1.jpg","file_name":"pmc3590050.pdf","download_url":"https://www.academia.edu/attachments/101022844/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Criteria_for_the_diagnosis_of_corticobas.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022844/pmc3590050-libre.pdf?1681332253=\u0026response-content-disposition=attachment%3B+filename%3DCriteria_for_the_diagnosis_of_corticobas.pdf\u0026Expires=1733270749\u0026Signature=ehjKHq4WDJhgp-NpsVIkxWm69iE87W8o2BwWZBUVI97oywrft-OsBGIpkBcbGgnD2c1F5iE4O5LvU1CLabdfUWT-myy89QRImjBuJo84IjOvqXbL7rgxIUsma4mG0H1WDs3fFeehp6yFhIniRyqf9PKWM6XMA5aQVkDd5eP~amXpqIYLTCNzQz0oWe513edM1JE-2~d3ApGqZZC-oK6-wqIf3doZ8z4wG15WA9W9Bc1fxrmQTgeM3VyRztqExcqZ6AQxRKrPxaFunK2tVi6xcGdZ8vgCN4MxH8RANP7rNgiJu1nbIXO0brcPy-l2cOoP8izo9eGKG8l4TS8AUGGGpg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Criteria_for_the_diagnosis_of_corticobasal_degeneration","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112181"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112181/Scales_to_assess_psychosis_in_Parkinsons_disease_Critique_and_recommendations"><img alt="Research paper thumbnail of Scales to assess psychosis in Parkinson's disease: Critique and recommendations" class="work-thumbnail" src="https://attachments.academia-assets.com/101022851/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112181/Scales_to_assess_psychosis_in_Parkinsons_disease_Critique_and_recommendations">Scales to assess psychosis in Parkinson's disease: Critique and recommendations</a></div><div class="wp-workCard_item"><span>Movement Disorders</span><span>, 2008</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f642b898f1ae125379edd5a9de9fe5cc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022851,"asset_id":100112181,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022851/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112181"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112181"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112181; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112181]").text(description); $(".js-view-count[data-work-id=100112181]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112181; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112181']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112181, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f642b898f1ae125379edd5a9de9fe5cc" } } $('.js-work-strip[data-work-id=100112181]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112181,"title":"Scales to assess psychosis in Parkinson's disease: Critique and recommendations","translated_title":"","metadata":{"publisher":"Wiley","grobid_abstract":"Psychotic symptoms are a frequent occurrence in Parkinson's disease (PD), affecting up to 50% of patients. The Movement Disorder Society established a Task Force on Rating Scales in PD, and this critique applies to published, peerreviewed rating psychosis scales used in PD psychosis studies. Twelve psychosis scales/questionnaires were reviewed. None of the reviewed scales adequately captured the entire phenomenology of PD psychosis. While the Task Force has labeled some scales as \"recommended\" or \"suggested\" based on the fulfilling-defined criteria, none of the current scales contained all the basic content, mechanistic and psychometric properties needed to capture PD psychotic phenomena and to measure clinical response over time. Different scales may be better for some settings versus others. Since one scale may not be able to serve all needs, a scale used to measure clinical response and change over time [such as the Clinical Global Impression Scale (CGIS)] may need to be combined with another scale better at cataloging specific features [such as the Neuropsychiatric Inventory (NPI) or Schedule for Assessment of Positive Symptoms (SAPS)]. At the present time, for clinical trials on PD psychosis assessing new treatments, the following are recommended primary outcome scales: NPI (for the cognitively impaired PD population or when a caregiver is required), SAPS, Positive and Negative Syndrome Scale (PANSS), or Brief Psychiatric Rating Scale (BPRS) (for the cognitively intact PD population or when the patient is the sole informant). 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112180"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112180/The_Impact_of_Antidepressant_Treatment_on_Cognitive_Functioning_in_Depressed_Patients_with_Parkinsons_Disease"><img alt="Research paper thumbnail of The Impact of Antidepressant Treatment on Cognitive Functioning in Depressed Patients with Parkinson's Disease" class="work-thumbnail" src="https://attachments.academia-assets.com/101022854/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112180/The_Impact_of_Antidepressant_Treatment_on_Cognitive_Functioning_in_Depressed_Patients_with_Parkinsons_Disease">The Impact of Antidepressant Treatment on Cognitive Functioning in Depressed Patients with Parkinson's Disease</a></div><div class="wp-workCard_item"><span>Journal of Neuropsychiatry</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e67ea1f5c53806d6d4f24d173b9b4789" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022854,"asset_id":100112180,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022854/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112180"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112180"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112180; 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The goal of this study was to examine the impact of the acute (8-week) and longer-term (24-week) antidepressant treatment on cognition in PD and to detail cognitive predictors of treatment response. Fifty-two depressed PD patients were enrolled in an NIH funded randomized-controlled trial of nortriptyline, paroxetine, and placebo. Neuropsychological testing was performed at baseline, and weeks eight and twenty-four. Higher baseline scores on measures of executive functioning, speed of processing, and verbal memory were associated with antidepressant response. Treatment responders did not exhibit larger gains in cognition than non-responders. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112179"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112179/Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor"><img alt="Research paper thumbnail of Long term safety and efficacy of unilateral deep brain stimulation of the thalamus for parkinsonian tremor" class="work-thumbnail" src="https://attachments.academia-assets.com/101022845/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112179/Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor">Long term safety and efficacy of unilateral deep brain stimulation of the thalamus for parkinsonian tremor</a></div><div class="wp-workCard_item"><span>Journal of Neurology, Neurosurgery &amp; Psychiatry</span><span>, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="df5db2273046fa6781b7ff6666cc0405" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022845,"asset_id":100112179,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022845/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112179"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112179"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112179; 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Twelve patients with Parkinson's disease underwent unilateral DBS of the thalamus for medication resistant tremor between 1994 and 1997. Patients were evaluated with the motor section of the unified Parkinson's disease rating scale (UPDRS) in the medication on state at baseline, 3 months, 12 months, and yearly thereafter. Three patients were lost to follow up. Nine patients had follow up evaluations greater than 24 months and were included in the analyses. The last postsurgical follow up occurred on average 40.0 (SD 17.2) months after surgery. Tremor scores were significantly improved with stimulation on at the long term follow up compared with baseline. There was no significant change in UPDRS motor scores at long term follow up compared with baseline. There was no significant change in any stimulus parameters from 3 months to the long term follow up. Two patients had asymptomatic intracerebral haemorrhages and one patient had a subcutaneous haematoma over the implantable pulse generator site. Stimulus related adverse reactions were mild and easily controlled with changes in stimulus parameters. Two patients had replacement of the implantable pulse generator due to normal battery depletion, one patient had lead repositioning due to migration, and one patient had the lead extension wire replaced due to erosion. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112178"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112178/Semantic_and_letter_category_naming_in_Alzheimers_patients_A_predictable_difference"><img alt="Research paper thumbnail of Semantic and letter category naming in Alzheimer's patients: A predictable difference" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112178/Semantic_and_letter_category_naming_in_Alzheimers_patients_A_predictable_difference">Semantic and letter category naming in Alzheimer's patients: A predictable difference</a></div><div class="wp-workCard_item"><span>Developmental Neuropsychology</span><span>, 1989</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Performance on semantic and letter category naming tasks of 32 Alzheimer&#x27;s disease (AD) pati...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Performance on semantic and letter category naming tasks of 32 Alzheimer&#x27;s disease (AD) patients from the University of California, San Diego (UCSD) Alzheimer&#x27;s Disease Research Center was analyzed and compared to performance on a variety of other ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112178"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112178"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112178; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112178]").text(description); $(".js-view-count[data-work-id=100112178]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112178; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112178']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112178, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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Troster","url":"https://independent.academia.edu/ATroster"},"attachments":[],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":169050,"name":"Developmental neuropsychology","url":"https://www.academia.edu/Documents/in/Developmental_neuropsychology"},{"id":224578,"name":"Multiple Regression","url":"https://www.academia.edu/Documents/in/Multiple_Regression"},{"id":229238,"name":"Developmental","url":"https://www.academia.edu/Documents/in/Developmental"},{"id":617201,"name":"Developmental Neuropsychology","url":"https://www.academia.edu/Documents/in/Developmental_Neuropsychology-1"},{"id":734113,"name":"University of Southern California","url":"https://www.academia.edu/Documents/in/University_of_Southern_California"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences"}],"urls":[{"id":30587778,"url":"http://www.tandfonline.com/doi/pdf/10.1080/87565648909540443"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112177"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression"><img alt="Research paper thumbnail of Neuropsychological Impairment in Parkinson's Disease With and Without Depression" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression">Neuropsychological Impairment in Parkinson's Disease With and Without Depression</a></div><div class="wp-workCard_item"><span>Archives of Neurology</span><span>, 1995</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To compare quantitative and qualitative aspects of neuropsychological test performance in patient...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson&amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson&amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination&amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups&amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson&amp;#39;s disease.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112177"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112177"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112177; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112177]").text(description); $(".js-view-count[data-work-id=100112177]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112177; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112177']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112177, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=100112177]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112177,"title":"Neuropsychological Impairment in Parkinson's Disease With and Without Depression","translated_title":"","metadata":{"abstract":"To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson\u0026amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson\u0026amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination\u0026amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups\u0026amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson\u0026amp;#39;s disease.","publisher":"American Medical Association (AMA)","publication_date":{"day":null,"month":null,"year":1995,"errors":{}},"publication_name":"Archives of Neurology"},"translated_abstract":"To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson\u0026amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson\u0026amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination\u0026amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups\u0026amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson\u0026amp;#39;s disease.","internal_url":"https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression","translated_internal_url":"","created_at":"2023-04-12T11:05:50.922-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112176"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112176/Continuous_Visual_Memory_Test_Performance_in_Healthy_Persons_60_to_94_Years_of_Age"><img alt="Research paper thumbnail of Continuous Visual Memory Test Performance in Healthy Persons 60 to 94 Years of Age" class="work-thumbnail" src="https://attachments.academia-assets.com/101022827/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112176/Continuous_Visual_Memory_Test_Performance_in_Healthy_Persons_60_to_94_Years_of_Age">Continuous Visual Memory Test Performance in Healthy Persons 60 to 94 Years of Age</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1998</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="74e91782f78f21cd87d248936b022b33" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022827,"asset_id":100112176,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022827/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112176; 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I., Fields, J. A., & Brooks, R" class="work-thumbnail" src="https://attachments.academia-assets.com/101022823/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112175/The_effects_of_depression_and_parkinsons_disease_on_cognitive_functioning_Norman_S_Troster_A_I_Fields_J_A_and_Brooks_R">The effects of depression and parkinson's disease on cognitive functioning Norman, S., Troster, A. I., Fields, J. A., & Brooks, R</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1997</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2fea70c11ca4b4013890108d6cd9a516" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022823,"asset_id":100112175,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022823/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112175"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112175"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112175; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112175]").text(description); $(".js-view-count[data-work-id=100112175]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112175; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112175']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112175, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2fea70c11ca4b4013890108d6cd9a516" } } $('.js-work-strip[data-work-id=100112175]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112175,"title":"The effects of depression and parkinson's disease on cognitive functioning Norman, S., Troster, A. 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Our study of two patients acutely exposed to low concentrations of TCE suggests that (a) acute, low-dose exposures are sufficient to produce the mild to moderate impairments in psychomotor speed, attention and memory also reported after chronic exposures; (b) these memory impairments may be characterized by storage and/or retrieval difficulties; (c) the neural damage produced by TCE exposure is likely to be diffuse, but temporal lobe structures supporting memory may be more sensitive to TCE exposure than other brain structures; and (d) even brief exposures can lead to prolonged, but not necessarily chronic mild to moderate cognitive impairment. 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In a third case, exposed to trichloroethane (TCA), the neuropsychological profile suggests that this substance has few, if any, neurobehavioral effects at low concentrations.","internal_url":"https://www.academia.edu/100112173/Neuropsychological_sequelae_of_exposure_to_the_chlorinated_hydrocarbon_solvents_trichloroethylene_and_trichloroethane","translated_internal_url":"","created_at":"2023-04-12T11:05:50.307-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Neuropsychological_sequelae_of_exposure_to_the_chlorinated_hydrocarbon_solvents_trichloroethylene_and_trichloroethane","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112172"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112172/Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_"><img alt="Research paper thumbnail of Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs)" class="work-thumbnail" src="https://attachments.academia-assets.com/101022825/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112172/Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_">Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs)</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1991</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4719d3f60938d87d262b2f7e669ce657" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022825,"asset_id":100112172,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022825/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112172"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112172"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112172; 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Since only a small minority of PCB-exposed patients demonstrate abnormalities on objective neurological measures (e.g., CT-scans, EEG. nerve conduction velocity), it is particularly unfortunate that objective neuropsychological data has not been published to substantiate patient complaints. The present study provides neuropsychological test data on two patients exposed to PCBs. In both cases, PCB exposure is documented by an analysis of PCB levels in the patients' work environments. Despite the absence of abnormalities on CT-scans and EEG, both patients displayed a variery of cognitive deficits and emotional disturbance. Serial assessment of one patient with high blood levels of PCBs revealed a dementia (sharing certain features with Alzheimer's disease) and an organic dective syndrome. Assessment of a second patient exposed to PCBs (but with no detectable blood levels of PCBs) suggested that his cognitive impairments were not due to PCB exposure. The present study provides data which points to the importance and sensitivity of neuropsychological examination in cases of PCB-exposure.","publication_date":{"day":null,"month":null,"year":1991,"errors":{}},"publication_name":"Archives of Clinical Neuropsychology","grobid_abstract_attachment_id":101022825},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112172/Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_","translated_internal_url":"","created_at":"2023-04-12T11:05:50.182-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022825,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022825/thumbnails/1.jpg","file_name":"0887-617728912990007-v20230412-1-3zaket.pdf","download_url":"https://www.academia.edu/attachments/101022825/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Dementia_as_a_neuropsychological_consequ.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022825/0887-617728912990007-v20230412-1-3zaket-libre.pdf?1681332270=\u0026response-content-disposition=attachment%3B+filename%3DDementia_as_a_neuropsychological_consequ.pdf\u0026Expires=1733270749\u0026Signature=W59u4RYKXjDX1amCQ5e47r2U0dZ50VtGUhIN9-nTUl1qgICkvVl9LDEKt4Rufimpu~noUXFHYq9ha7WpznUNTsEOycsQn03eTYNEQt1RMZzxvV1yI3F3fsafFueaxN3~ph-L~ZCF2JoKOb1x260WlpsgzCEzZXdi-7sW3QVRlr3naGaBW6LEgau-n-QI5c183MEZVAcjaC7T37aCOGWX7s2PpLXfDwFTgrNcVnRjwSDXi3WQnO3C5lQacYqiUbacnS6NDlQzRwQy12mT~MLShYRsf~31WbjMoHrqxlz7z6NVRt9d4RJiUaq6oFTHFc65yq1yidQyHH0kl7IKRBXCYg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_","translated_slug":"","page_count":18,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112171"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112171/Assessing_cognitive_change_in_Parkinsons_disease_Development_of_practice_effect_corrected_reliable_change_indices"><img alt="Research paper thumbnail of Assessing cognitive change in Parkinson's disease: Development of practice effect-corrected reliable change indices" class="work-thumbnail" src="https://attachments.academia-assets.com/101022793/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112171/Assessing_cognitive_change_in_Parkinsons_disease_Development_of_practice_effect_corrected_reliable_change_indices">Assessing cognitive change in Parkinson's disease: Development of practice effect-corrected reliable change indices</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2c7d3537c08751cdfa92dfff292d5bc0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022793,"asset_id":100112171,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022793/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112171"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112171"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112171; 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This study provides test-retest stability, expected practice effects, and practice-corrected reliable change indices for several commonly used neuropsychological tests from 62 older adults with mostly mild PD who underwent repeat evaluations approximately 17 months apart. At the group level, results showed adequate test-retest reliability (Spearman's rho range = 0.24-0.86) and generally small practice effects (Cohen's d range = 0.00-0.50). Application of reliable change indices using 90% confidence intervals showed the expected number of individuals (generally 10% or fewer) with statistically meaningful improvements (range = 0-12%) or declines (range = 2-8%) in cognitive performance at retest. Limitations discussed include ceiling effects at test baseline, sample homogeneity, interpretative cautions, and generalizability of study results. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112170"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112170/Action_verbal_fluency_Normative_data_for_the_elderly_Piatt_A_Fields_J_Paolo_A_and_Troster_A"><img alt="Research paper thumbnail of Action verbal fluency: Normative data for the elderly Piatt, A., Fields, J., Paolo, A., & Troster, A" class="work-thumbnail" src="https://attachments.academia-assets.com/101022824/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112170/Action_verbal_fluency_Normative_data_for_the_elderly_Piatt_A_Fields_J_Paolo_A_and_Troster_A">Action verbal fluency: Normative data for the elderly Piatt, A., Fields, J., Paolo, A., & Troster, A</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1999</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="38aba022138a7f3383845ca6eec53d20" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022824,"asset_id":100112170,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022824/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112170"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112170"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112170; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112169"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112169/Cognitive_effects_of_bilateral_subthalamic_nucleus_stimulation_for_the_treatment_of_Parkinsons_disease"><img alt="Research paper thumbnail of Cognitive effects of bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease" class="work-thumbnail" src="https://attachments.academia-assets.com/101022829/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112169/Cognitive_effects_of_bilateral_subthalamic_nucleus_stimulation_for_the_treatment_of_Parkinsons_disease">Cognitive effects of bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1999</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="fc6e9732d96909f9612c449885450dc0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022829,"asset_id":100112169,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022829/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112169"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112169"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112169; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112169]").text(description); $(".js-view-count[data-work-id=100112169]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112169; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112169']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112169, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "fc6e9732d96909f9612c449885450dc0" } } $('.js-work-strip[data-work-id=100112169]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112169,"title":"Cognitive effects of bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"Surgical interventions, especially deep brain stimulation procedures, for treatment of refractory Parkinson's disease motor symptoms are becoming more common. In particular, interest in bilateral stimulation of the subthalamic nucleus (STN) has become widespread, given its apparent ability to alleviate nearly all debilitating motor symptoms. A few small studies suggest that thalamic and pallidal stimulation procedures may be cognitively safe, but no studies to date have reported neurobehavioral effects of STN stimulation. This, then, is the purpose of the current study. Five patients (4 male, 1 female), four of them right-handed, were administered a comprehensive battery of neuropsychological tests approximately 3 months before and 7 months following surgery. Mean demographic and disease characteristics were as follows: age 56.6 years, education 11.4 years; age at diagnosis 49.6 years; and disease duration 9.0 years. Patients were of average intelligence (estimated verbal IQ, 100.4) and mean DRS Total score before surgery was 130. Nonparametric analyses revealed no significant change in overall level of cognitive functioning, attention/concentration, conceptualization, language, visuomotor coordination, visuoperceptual functioning, memory, and mood state. When examining changes of 2 or more standard deviations on an individual patient basis, 2 patients' performance gained higher scores on DRS Construction, while 2 patients declined on the interference condition of the Stroop. Two patients showed decline on category fluency. 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The aim of this international study was to evaluate the predictive validity of the comprehensive (level II) version of these criteria by assessment of their contribution to the hazard of PD dementia. Individual patient data were selected from four separate studies on cognition in PD that provided information on demographics, motor examination, depression, neuropsychological examination suitable for application of level II criteria, and longitudinal follow-up for conversion to dementia. Survival analysis evaluated the predictive value of level II criteria for cognitive decline toward dementia as expressed by the relative hazard of dementia. A total of 467 patients were included. The analyses showed a clear contribution of impairment according to level II mild cognitive impairment criteria, age, and severity of PD motor symptoms to the hazard of dementia. Th...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="30f32b47ca947b7a1f6d3617d3f3f558" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022831,"asset_id":100112187,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022831/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112187"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112187"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112187; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112187]").text(description); $(".js-view-count[data-work-id=100112187]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112187; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112187']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112187, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "30f32b47ca947b7a1f6d3617d3f3f558" } } $('.js-work-strip[data-work-id=100112187]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112187,"title":"Mild cognitive impairment as a risk factor for Parkinson's disease dementia","translated_title":"","metadata":{"abstract":"The International Parkinson and Movement Disorder Society criteria for mild cognitive impairment in PD were recently formulated. 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However, low statistical power is problematic in neuropsychological research involving clinical populations and novel interventions for which available sample sizes are often limited. One notable example of this problem is evident in the literature regarding the cognitive sequelae of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in persons with Parkinson's disease (PD). In the current review, a post hoc estimate of the statistical power of 30 studies examining cognitive effects of STN DBS in PD revealed adequate power to detect substantial cognitive declines (i.e., very large effect sizes), but surprisingly low estimated power to detect cognitive changes associated with conventionally small, medium, and large effect sizes. Such wide spread Type II error risk in the STN DBS cognitive outcomes literature may affect the clinical decisionmaking process as concerns the possible risk of postsurgical cognitive morbidity, as well as conceptual inferences to be drawn regarding the role of the STN in higher-level cognitive functions. Statistical and methodological recommendations (e.g., meta-analysis) are offered to enhance the power of current and future studies examining the neuropsychological sequelae of STN DBS in PD.","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"The Clinical Neuropsychologist","grobid_abstract_attachment_id":101022848},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112183/Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease","translated_internal_url":"","created_at":"2023-04-12T11:05:52.223-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022848,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022848/thumbnails/1.jpg","file_name":"2Parsons_TCN_Woods_STNPower_06.pdf","download_url":"https://www.academia.edu/attachments/101022848/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Statistical_Power_of_Studies_Examining_t.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022848/2Parsons_TCN_Woods_STNPower_06-libre.pdf?1681332254=\u0026response-content-disposition=attachment%3B+filename%3DStatistical_Power_of_Studies_Examining_t.pdf\u0026Expires=1733270749\u0026Signature=BFCXJI5lPCQUD7Qe-~QpT2N22N9p2vSU9jQos8LgcaOaF-xmILKTLOengBsDNF-V5r4dmY7f6SCWsgC3xmHofhl7Tt79~9KG8i7OA0bB7I3TgrNlfLWmM0vTdAyugK79myhcN3rvl64V9mpIRgEabYIAwYQ5tFNsTKT7J9xo6xDmcFPQfl6~255lWDGJWRYRFW3CzcbZxaure47tT6IPPyuM7Loo3D4WS2UVoizZJcM3hftvRlUy3O-VOwnVW0PtFqFkTsdU0BhJbsuWxVaoe3Xqf5w0jY8uY1qyX0Ng1hMjOW9ukCcht9xQ9p1auuvrAGl-sBohOWXkkE1blMTbEA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Statistical_Power_of_Studies_Examining_the_Cognitive_Effects_of_Subthalamic_Nucleus_Deep_Brain_Stimulation_in_Parkinsons_Disease","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112182"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration"><img alt="Research paper thumbnail of Criteria for the diagnosis of corticobasal degeneration" class="work-thumbnail" src="https://attachments.academia-assets.com/101022844/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration">Criteria for the diagnosis of corticobasal degeneration</a></div><div class="wp-workCard_item"><span>Neurology</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ca55d27efe5ca6ef574d7e4c82e24f45" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022844,"asset_id":100112182,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022844/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112182"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112182"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112182; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112182]").text(description); $(".js-view-count[data-work-id=100112182]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112182; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112182']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112182, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ca55d27efe5ca6ef574d7e4c82e24f45" } } $('.js-work-strip[data-work-id=100112182]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112182,"title":"Criteria for the diagnosis of corticobasal degeneration","translated_title":"","metadata":{"publisher":"Ovid Technologies (Wolters Kluwer Health)","grobid_abstract":"Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations. An international consortium of behavioral neurology, neuropsychology, and movement disorders specialists developed new criteria based on consensus and a systematic literature review. Clinical diagnoses (early or late) were identified for 267 nonoverlapping pathologically confirmed CBD cases from published reports and brain banks. Combined with consensus, 4 CBD phenotypes emerged: corticobasal syndrome (CBS), frontal behavioral-spatial syndrome (FBS), nonfluent/agrammatic variant of primary progressive aphasia (naPPA), and progressive supranuclear palsy syndrome (PSPS). Clinical features of CBD cases were extracted from descriptions of 209 brain bank and published patients, providing a comprehensive description of CBD and correcting common misconceptions. Clinical CBD phenotypes and features were combined to create 2 sets of criteria: more specific clinical research criteria for probable CBD and broader criteria for possible CBD that are more inclusive but have a higher chance to detect other tau-based pathologies. Probable CBD criteria require insidious onset and gradual progression for at least 1 year, age at onset $50 years, no similar family history or known tau mutations, and a clinical phenotype of probable CBS or either FBS or naPPA with at least 1 CBS feature. The possible CBD category uses similar criteria but has no restrictions on age or family history, allows tau mutations, permits less rigorous phenotype fulfillment, and includes a PSPS phenotype. Future validation and refinement of the proposed criteria are needed. Neurology â 2013;80:496-503 GLOSSARY AD 5 Alzheimer disease; AOS 5 apraxia of speech; CBD 5 corticobasal degeneration; CBS 5 corticobasal syndrome; CJD 5 Creutzfeldt-Jakob disease; cr-CBD 5 clinical research criteria for probable corticobasal degeneration; DLB 5 dementia with Lewy bodies; FTD 5 frontotemporal dementia; FTLD-TDP 5 frontotemporal lobar degeneration with TDP-43 immunoreactive inclusions; GRN 5 granulin; p-CBD 5 possible corticobasal degeneration criteria; PD 5 Parkinson disease; PNFA 5 progressive nonfluent aphasia; PPA 5 primary progressive aphasia; PSP 5 progressive supranuclear palsy; PSPS 5 progressive supranuclear palsy syndrome.","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"Neurology","grobid_abstract_attachment_id":101022844},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112182/Criteria_for_the_diagnosis_of_corticobasal_degeneration","translated_internal_url":"","created_at":"2023-04-12T11:05:52.050-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022844,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022844/thumbnails/1.jpg","file_name":"pmc3590050.pdf","download_url":"https://www.academia.edu/attachments/101022844/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Criteria_for_the_diagnosis_of_corticobas.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022844/pmc3590050-libre.pdf?1681332253=\u0026response-content-disposition=attachment%3B+filename%3DCriteria_for_the_diagnosis_of_corticobas.pdf\u0026Expires=1733270749\u0026Signature=ehjKHq4WDJhgp-NpsVIkxWm69iE87W8o2BwWZBUVI97oywrft-OsBGIpkBcbGgnD2c1F5iE4O5LvU1CLabdfUWT-myy89QRImjBuJo84IjOvqXbL7rgxIUsma4mG0H1WDs3fFeehp6yFhIniRyqf9PKWM6XMA5aQVkDd5eP~amXpqIYLTCNzQz0oWe513edM1JE-2~d3ApGqZZC-oK6-wqIf3doZ8z4wG15WA9W9Bc1fxrmQTgeM3VyRztqExcqZ6AQxRKrPxaFunK2tVi6xcGdZ8vgCN4MxH8RANP7rNgiJu1nbIXO0brcPy-l2cOoP8izo9eGKG8l4TS8AUGGGpg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Criteria_for_the_diagnosis_of_corticobasal_degeneration","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112181"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112181/Scales_to_assess_psychosis_in_Parkinsons_disease_Critique_and_recommendations"><img alt="Research paper thumbnail of Scales to assess psychosis in Parkinson's disease: Critique and recommendations" class="work-thumbnail" src="https://attachments.academia-assets.com/101022851/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112181/Scales_to_assess_psychosis_in_Parkinsons_disease_Critique_and_recommendations">Scales to assess psychosis in Parkinson's disease: Critique and recommendations</a></div><div class="wp-workCard_item"><span>Movement Disorders</span><span>, 2008</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f642b898f1ae125379edd5a9de9fe5cc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022851,"asset_id":100112181,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022851/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112181"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112181"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112181; 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The Movement Disorder Society established a Task Force on Rating Scales in PD, and this critique applies to published, peerreviewed rating psychosis scales used in PD psychosis studies. Twelve psychosis scales/questionnaires were reviewed. None of the reviewed scales adequately captured the entire phenomenology of PD psychosis. While the Task Force has labeled some scales as \"recommended\" or \"suggested\" based on the fulfilling-defined criteria, none of the current scales contained all the basic content, mechanistic and psychometric properties needed to capture PD psychotic phenomena and to measure clinical response over time. Different scales may be better for some settings versus others. Since one scale may not be able to serve all needs, a scale used to measure clinical response and change over time [such as the Clinical Global Impression Scale (CGIS)] may need to be combined with another scale better at cataloging specific features [such as the Neuropsychiatric Inventory (NPI) or Schedule for Assessment of Positive Symptoms (SAPS)]. At the present time, for clinical trials on PD psychosis assessing new treatments, the following are recommended primary outcome scales: NPI (for the cognitively impaired PD population or when a caregiver is required), SAPS, Positive and Negative Syndrome Scale (PANSS), or Brief Psychiatric Rating Scale (BPRS) (for the cognitively intact PD population or when the patient is the sole informant). 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112180"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112180/The_Impact_of_Antidepressant_Treatment_on_Cognitive_Functioning_in_Depressed_Patients_with_Parkinsons_Disease"><img alt="Research paper thumbnail of The Impact of Antidepressant Treatment on Cognitive Functioning in Depressed Patients with Parkinson's Disease" class="work-thumbnail" src="https://attachments.academia-assets.com/101022854/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112180/The_Impact_of_Antidepressant_Treatment_on_Cognitive_Functioning_in_Depressed_Patients_with_Parkinsons_Disease">The Impact of Antidepressant Treatment on Cognitive Functioning in Depressed Patients with Parkinson's Disease</a></div><div class="wp-workCard_item"><span>Journal of Neuropsychiatry</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e67ea1f5c53806d6d4f24d173b9b4789" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022854,"asset_id":100112180,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022854/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112180"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112180"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112180; 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The goal of this study was to examine the impact of the acute (8-week) and longer-term (24-week) antidepressant treatment on cognition in PD and to detail cognitive predictors of treatment response. Fifty-two depressed PD patients were enrolled in an NIH funded randomized-controlled trial of nortriptyline, paroxetine, and placebo. Neuropsychological testing was performed at baseline, and weeks eight and twenty-four. Higher baseline scores on measures of executive functioning, speed of processing, and verbal memory were associated with antidepressant response. Treatment responders did not exhibit larger gains in cognition than non-responders. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112179"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112179/Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor"><img alt="Research paper thumbnail of Long term safety and efficacy of unilateral deep brain stimulation of the thalamus for parkinsonian tremor" class="work-thumbnail" src="https://attachments.academia-assets.com/101022845/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112179/Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor">Long term safety and efficacy of unilateral deep brain stimulation of the thalamus for parkinsonian tremor</a></div><div class="wp-workCard_item"><span>Journal of Neurology, Neurosurgery &amp; Psychiatry</span><span>, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="df5db2273046fa6781b7ff6666cc0405" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022845,"asset_id":100112179,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022845/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112179"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112179"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112179; 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Twelve patients with Parkinson's disease underwent unilateral DBS of the thalamus for medication resistant tremor between 1994 and 1997. Patients were evaluated with the motor section of the unified Parkinson's disease rating scale (UPDRS) in the medication on state at baseline, 3 months, 12 months, and yearly thereafter. Three patients were lost to follow up. Nine patients had follow up evaluations greater than 24 months and were included in the analyses. The last postsurgical follow up occurred on average 40.0 (SD 17.2) months after surgery. Tremor scores were significantly improved with stimulation on at the long term follow up compared with baseline. There was no significant change in UPDRS motor scores at long term follow up compared with baseline. There was no significant change in any stimulus parameters from 3 months to the long term follow up. Two patients had asymptomatic intracerebral haemorrhages and one patient had a subcutaneous haematoma over the implantable pulse generator site. Stimulus related adverse reactions were mild and easily controlled with changes in stimulus parameters. Two patients had replacement of the implantable pulse generator due to normal battery depletion, one patient had lead repositioning due to migration, and one patient had the lead extension wire replaced due to erosion. In conclusion, unilateral DBS of the thalamus has long term eYcacy for treatment of tremor due to Parkinson's disease.","publication_date":{"day":null,"month":null,"year":2001,"errors":{}},"publication_name":"Journal of Neurology, Neurosurgery \u0026amp; Psychiatry","grobid_abstract_attachment_id":101022845},"translated_abstract":null,"internal_url":"https://www.academia.edu/100112179/Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor","translated_internal_url":"","created_at":"2023-04-12T11:05:51.308-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101022845,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101022845/thumbnails/1.jpg","file_name":"682.full.pdf","download_url":"https://www.academia.edu/attachments/101022845/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Long_term_safety_and_efficacy_of_unilate.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101022845/682.full-libre.pdf?1681332254=\u0026response-content-disposition=attachment%3B+filename%3DLong_term_safety_and_efficacy_of_unilate.pdf\u0026Expires=1733270749\u0026Signature=AJFN40TgdlUaoR4xk1PNzsLteMAau-koRB68JFeUCMvpuNuZgNpNfmjv9aEkrOG7rtzUf9oV6XpD4iFzPaRzFr2-9tvIAeJFccgqdZiA7DQD4w7KPm~5d5Sl5cIDQ4ikebFeXKKPq04spKl2YqXcU3fY4Ipu4afVearMs2WWeNVCsmOKE5wLMftPwPSW3bA6POGritMHKW9En7GaDz1r6j2ag8CipVmFroUhAHh7WD6qURdBiL4UNEd34fI7-bHOObQYNR2r7LzRgwZoEY06V5esxliJV1v9d2lMwzFZOA3pv5pXbj4MFEDwgse6cSthO2PS5JyywhuHXwou5qoKsw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Long_term_safety_and_efficacy_of_unilateral_deep_brain_stimulation_of_the_thalamus_for_parkinsonian_tremor","translated_slug":"","page_count":3,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112178"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112178/Semantic_and_letter_category_naming_in_Alzheimers_patients_A_predictable_difference"><img alt="Research paper thumbnail of Semantic and letter category naming in Alzheimer's patients: A predictable difference" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112178/Semantic_and_letter_category_naming_in_Alzheimers_patients_A_predictable_difference">Semantic and letter category naming in Alzheimer's patients: A predictable difference</a></div><div class="wp-workCard_item"><span>Developmental Neuropsychology</span><span>, 1989</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Performance on semantic and letter category naming tasks of 32 Alzheimer&#x27;s disease (AD) pati...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Performance on semantic and letter category naming tasks of 32 Alzheimer&#x27;s disease (AD) patients from the University of California, San Diego (UCSD) Alzheimer&#x27;s Disease Research Center was analyzed and compared to performance on a variety of other ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112178"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112178"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112178; 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Troster","url":"https://independent.academia.edu/ATroster"},"attachments":[],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":169050,"name":"Developmental neuropsychology","url":"https://www.academia.edu/Documents/in/Developmental_neuropsychology"},{"id":224578,"name":"Multiple Regression","url":"https://www.academia.edu/Documents/in/Multiple_Regression"},{"id":229238,"name":"Developmental","url":"https://www.academia.edu/Documents/in/Developmental"},{"id":617201,"name":"Developmental Neuropsychology","url":"https://www.academia.edu/Documents/in/Developmental_Neuropsychology-1"},{"id":734113,"name":"University of Southern California","url":"https://www.academia.edu/Documents/in/University_of_Southern_California"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences"}],"urls":[{"id":30587778,"url":"http://www.tandfonline.com/doi/pdf/10.1080/87565648909540443"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112177"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression"><img alt="Research paper thumbnail of Neuropsychological Impairment in Parkinson's Disease With and Without Depression" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression">Neuropsychological Impairment in Parkinson's Disease With and Without Depression</a></div><div class="wp-workCard_item"><span>Archives of Neurology</span><span>, 1995</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To compare quantitative and qualitative aspects of neuropsychological test performance in patient...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson&amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson&amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination&amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups&amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson&amp;#39;s disease.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112177"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112177"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112177; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112177]").text(description); $(".js-view-count[data-work-id=100112177]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112177; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112177']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112177, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=100112177]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112177,"title":"Neuropsychological Impairment in Parkinson's Disease With and Without Depression","translated_title":"","metadata":{"abstract":"To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson\u0026amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson\u0026amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination\u0026amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups\u0026amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson\u0026amp;#39;s disease.","publisher":"American Medical Association (AMA)","publication_date":{"day":null,"month":null,"year":1995,"errors":{}},"publication_name":"Archives of Neurology"},"translated_abstract":"To compare quantitative and qualitative aspects of neuropsychological test performance in patients with Parkinson\u0026amp;#39;s disease who currently had depression (PDD) and those without depression (PDN) so as to evaluate the influence of depression on cognition in Parkinson\u0026amp;#39;s disease. Cross-sectional comparisons among PDN, PDD, and normal control (NC) groups. The setting was a neurodegenerative disease research center in a teaching hospital. Groups consisted of 44 patients with PDN and 44 patients with PDD matched for age, education, gender, age at onset of disease, disease duration, and disease severity; a group of 44 NC subjects matched for age, education, and gender; and a second set of comparisons between 15 patients with PDN and 15 patients with PDD also matched for overall severity of cognitive impairment. The neuropsychological measures used were the Mattis Dementia Rating Scale, Beck Depression Inventory, Wisconsin Card Sorting Test, Controlled Oral Word Association Test, Logical Memory subtest of the Wechsler Memory Scale-Revised, Digit Span subtest of the Wechsler Adult Intelligence Scale-Revised, and the Boston Diagnostic Aphasia Examination\u0026amp;#39;s Animal Naming test and Boston Naming Test. Relative to the NC group, both PDN and PDD groups demonstrated impairments in immediate and delayed verbal recall, semantic fluency, and problem solving. When PDN and PDD groups were matched for demographic and disease variables, only the PDD group evidenced impairment relative to NC in visual confrontation naming, and in lexical and semantic fluency. In addition, impairments on immediate recall and semantic fluency in the PDD group were more pronounced than those in the PDN group. However, when PDN and PDD groups were also matched for overall severity of cognitive impairment, no significant differences emerged among the two groups\u0026amp;#39; neuropsychological test performances. Depression exacerbates some memory and language impairments associated with PD, even when the PDN and PDD groups are matched for demographic and disease variables. However, the extent and pattern of cognitive impairment is similar in PDN and PDD when the groups are also matched also for overall severity of cognitive impairment. Depression influences the quantity rather than the quality of cognitive impairment associated with Parkinson\u0026amp;#39;s disease.","internal_url":"https://www.academia.edu/100112177/Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression","translated_internal_url":"","created_at":"2023-04-12T11:05:50.922-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Neuropsychological_Impairment_in_Parkinsons_Disease_With_and_Without_Depression","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112176"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112176/Continuous_Visual_Memory_Test_Performance_in_Healthy_Persons_60_to_94_Years_of_Age"><img alt="Research paper thumbnail of Continuous Visual Memory Test Performance in Healthy Persons 60 to 94 Years of Age" class="work-thumbnail" src="https://attachments.academia-assets.com/101022827/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112176/Continuous_Visual_Memory_Test_Performance_in_Healthy_Persons_60_to_94_Years_of_Age">Continuous Visual Memory Test Performance in Healthy Persons 60 to 94 Years of Age</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1998</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="74e91782f78f21cd87d248936b022b33" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022827,"asset_id":100112176,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022827/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112176; 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Our study of two patients acutely exposed to low concentrations of TCE suggests that (a) acute, low-dose exposures are sufficient to produce the mild to moderate impairments in psychomotor speed, attention and memory also reported after chronic exposures; (b) these memory impairments may be characterized by storage and/or retrieval difficulties; (c) the neural damage produced by TCE exposure is likely to be diffuse, but temporal lobe structures supporting memory may be more sensitive to TCE exposure than other brain structures; and (d) even brief exposures can lead to prolonged, but not necessarily chronic mild to moderate cognitive impairment. In a third case, exposed to trichloroethane (TCA), the neuropsychological profile suggests that this substance has few, if any, neurobehavioral effects at low concentrations.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112173"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112173"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112173; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100112173]").text(description); $(".js-view-count[data-work-id=100112173]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100112173; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100112173']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100112173, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=100112173]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112173,"title":"Neuropsychological sequelae of exposure to the chlorinated hydrocarbon solvents trichloroethylene and trichloroethane","translated_title":"","metadata":{"abstract":"Reports in the literature concerning the acute neurobehavioral effects of trichloroethylene (TCE) and trichloroethane (TCA) conflict as to whether or not cognitive deficits ensue. Our study of two patients acutely exposed to low concentrations of TCE suggests that (a) acute, low-dose exposures are sufficient to produce the mild to moderate impairments in psychomotor speed, attention and memory also reported after chronic exposures; (b) these memory impairments may be characterized by storage and/or retrieval difficulties; (c) the neural damage produced by TCE exposure is likely to be diffuse, but temporal lobe structures supporting memory may be more sensitive to TCE exposure than other brain structures; and (d) even brief exposures can lead to prolonged, but not necessarily chronic mild to moderate cognitive impairment. In a third case, exposed to trichloroethane (TCA), the neuropsychological profile suggests that this substance has few, if any, neurobehavioral effects at low concentrations.","publisher":"Oxford University Press (OUP)","publication_date":{"day":null,"month":null,"year":1990,"errors":{}},"publication_name":"Archives of Clinical Neuropsychology"},"translated_abstract":"Reports in the literature concerning the acute neurobehavioral effects of trichloroethylene (TCE) and trichloroethane (TCA) conflict as to whether or not cognitive deficits ensue. Our study of two patients acutely exposed to low concentrations of TCE suggests that (a) acute, low-dose exposures are sufficient to produce the mild to moderate impairments in psychomotor speed, attention and memory also reported after chronic exposures; (b) these memory impairments may be characterized by storage and/or retrieval difficulties; (c) the neural damage produced by TCE exposure is likely to be diffuse, but temporal lobe structures supporting memory may be more sensitive to TCE exposure than other brain structures; and (d) even brief exposures can lead to prolonged, but not necessarily chronic mild to moderate cognitive impairment. In a third case, exposed to trichloroethane (TCA), the neuropsychological profile suggests that this substance has few, if any, neurobehavioral effects at low concentrations.","internal_url":"https://www.academia.edu/100112173/Neuropsychological_sequelae_of_exposure_to_the_chlorinated_hydrocarbon_solvents_trichloroethylene_and_trichloroethane","translated_internal_url":"","created_at":"2023-04-12T11:05:50.307-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36210205,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Neuropsychological_sequelae_of_exposure_to_the_chlorinated_hydrocarbon_solvents_trichloroethylene_and_trichloroethane","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36210205,"first_name":"A.","middle_initials":null,"last_name":"Troster","page_name":"ATroster","domain_name":"independent","created_at":"2015-10-14T06:00:58.898-07:00","display_name":"A. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112172"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112172/Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_"><img alt="Research paper thumbnail of Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs)" class="work-thumbnail" src="https://attachments.academia-assets.com/101022825/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112172/Dementia_as_a_neuropsychological_consequence_of_chronic_occupational_exposure_to_polychlorinated_biphenyls_PCBs_">Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs)</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1991</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4719d3f60938d87d262b2f7e669ce657" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022825,"asset_id":100112172,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022825/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112172"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112172"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112172; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4719d3f60938d87d262b2f7e669ce657" } } $('.js-work-strip[data-work-id=100112172]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100112172,"title":"Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs)","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"Previous epidemiological and clinical studies of humans exposed to polychlorinated biphenyls (PCBs) indicate that the majority of patients have neurological complaints (e.g.# headache, vertigo, paresthesias, poor memory and concentration, fatigue, depression). Since only a small minority of PCB-exposed patients demonstrate abnormalities on objective neurological measures (e.g., CT-scans, EEG. nerve conduction velocity), it is particularly unfortunate that objective neuropsychological data has not been published to substantiate patient complaints. The present study provides neuropsychological test data on two patients exposed to PCBs. In both cases, PCB exposure is documented by an analysis of PCB levels in the patients' work environments. Despite the absence of abnormalities on CT-scans and EEG, both patients displayed a variery of cognitive deficits and emotional disturbance. Serial assessment of one patient with high blood levels of PCBs revealed a dementia (sharing certain features with Alzheimer's disease) and an organic dective syndrome. Assessment of a second patient exposed to PCBs (but with no detectable blood levels of PCBs) suggested that his cognitive impairments were not due to PCB exposure. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112171"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112171/Assessing_cognitive_change_in_Parkinsons_disease_Development_of_practice_effect_corrected_reliable_change_indices"><img alt="Research paper thumbnail of Assessing cognitive change in Parkinson's disease: Development of practice effect-corrected reliable change indices" class="work-thumbnail" src="https://attachments.academia-assets.com/101022793/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112171/Assessing_cognitive_change_in_Parkinsons_disease_Development_of_practice_effect_corrected_reliable_change_indices">Assessing cognitive change in Parkinson's disease: Development of practice effect-corrected reliable change indices</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2c7d3537c08751cdfa92dfff292d5bc0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022793,"asset_id":100112171,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022793/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112171"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112171"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112171; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112170"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112170/Action_verbal_fluency_Normative_data_for_the_elderly_Piatt_A_Fields_J_Paolo_A_and_Troster_A"><img alt="Research paper thumbnail of Action verbal fluency: Normative data for the elderly Piatt, A., Fields, J., Paolo, A., & Troster, A" class="work-thumbnail" src="https://attachments.academia-assets.com/101022824/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112170/Action_verbal_fluency_Normative_data_for_the_elderly_Piatt_A_Fields_J_Paolo_A_and_Troster_A">Action verbal fluency: Normative data for the elderly Piatt, A., Fields, J., Paolo, A., & Troster, A</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1999</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="38aba022138a7f3383845ca6eec53d20" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022824,"asset_id":100112170,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022824/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112170"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112170"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112170; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100112169"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100112169/Cognitive_effects_of_bilateral_subthalamic_nucleus_stimulation_for_the_treatment_of_Parkinsons_disease"><img alt="Research paper thumbnail of Cognitive effects of bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease" class="work-thumbnail" src="https://attachments.academia-assets.com/101022829/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100112169/Cognitive_effects_of_bilateral_subthalamic_nucleus_stimulation_for_the_treatment_of_Parkinsons_disease">Cognitive effects of bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease</a></div><div class="wp-workCard_item"><span>Archives of Clinical Neuropsychology</span><span>, 1999</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="fc6e9732d96909f9612c449885450dc0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":101022829,"asset_id":100112169,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/101022829/download_file?st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&st=MTczMzI2NzE0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100112169"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100112169"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100112169; 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In particular, interest in bilateral stimulation of the subthalamic nucleus (STN) has become widespread, given its apparent ability to alleviate nearly all debilitating motor symptoms. A few small studies suggest that thalamic and pallidal stimulation procedures may be cognitively safe, but no studies to date have reported neurobehavioral effects of STN stimulation. This, then, is the purpose of the current study. Five patients (4 male, 1 female), four of them right-handed, were administered a comprehensive battery of neuropsychological tests approximately 3 months before and 7 months following surgery. Mean demographic and disease characteristics were as follows: age 56.6 years, education 11.4 years; age at diagnosis 49.6 years; and disease duration 9.0 years. Patients were of average intelligence (estimated verbal IQ, 100.4) and mean DRS Total score before surgery was 130. Nonparametric analyses revealed no significant change in overall level of cognitive functioning, attention/concentration, conceptualization, language, visuomotor coordination, visuoperceptual functioning, memory, and mood state. When examining changes of 2 or more standard deviations on an individual patient basis, 2 patients' performance gained higher scores on DRS Construction, while 2 patients declined on the interference condition of the Stroop. Two patients showed decline on category fluency. 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