CINXE.COM
Andrew Fraser | Donnelly Centre for Cellular and Biomolecular Research
<!DOCTYPE html> <html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ og: http://ogp.me/ns# rdfs: http://www.w3.org/2000/01/rdf-schema# schema: http://schema.org/ sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema# " > <head> <meta charset="utf-8" /> <script async src="https://www.googletagmanager.com/gtag/js?id=UA-34496632-11"></script> <script>window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag("config", "UA-34496632-11", {"groups":"default","anonymize_ip":true,"page_placeholder":"PLACEHOLDER_page_path","allow_ad_personalization_signals":false});gtag("config", " G-M7KC4MMZQB", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","allow_ad_personalization_signals":false});</script> <link rel="canonical" href="https://thedonnellycentre.utoronto.ca/faculty/andrew-fraser" /> <meta property="og:type" content="faculty_member" /> <meta property="og:url" content="https://thedonnellycentre.utoronto.ca/faculty/andrew-fraser" /> <meta property="og:title" content="Andrew Fraser" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:title" content="Andrew Fraser" /> <meta name="twitter:site" content="@uoftmedicine" /> <meta name="twitter:url" content="https://thedonnellycentre.utoronto.ca/faculty/andrew-fraser" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <link rel="icon" href="/themes/webpac/favicon.ico" type="image/vnd.microsoft.icon" /> <script src="/sites/default/files/google_tag/w2_donnelly_container/google_tag.script.js?snbacp" defer></script> <title>Andrew Fraser | Donnelly Centre for Cellular and Biomolecular Research</title> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_WPvkJYArLjssffZA64GguBXiMXMaSKmVAQSEnSows7o.css?delta=0&language=en&theme=webpac&include=eJw9zEEOgCAMBMAPEXkSKXXRJrQQW2L8vZ68zWmY-ETry8_MPzeFrcTLY2ihXcWykljAyBjFRgjDkz8e0FzJkW7USZyPPir11KQHrm-cIcNevwonHA" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_DwzK_729yrF3MWYc4MV-rDk_Gf6nJ4QsiDnoXFRZlt4.css?delta=1&language=en&theme=webpac&include=eJw9zEEOgCAMBMAPEXkSKXXRJrQQW2L8vZ68zWmY-ETry8_MPzeFrcTLY2ihXcWykljAyBjFRgjDkz8e0FzJkW7USZyPPir11KQHrm-cIcNevwonHA" /> <script src="/libraries/fontawesome/js/fontawesome.min.js?v=6.4.0" defer></script> <script src="/libraries/fontawesome/js/solid.min.js?v=6.4.0" defer></script> <script src="/libraries/fontawesome/js/brands.min.js?v=6.4.0" defer></script> </head> <body id="page" class="l-page"> <nav><a href="#main-content" class="u-visually--hidden focusable"> Skip to main content </a></nav> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5VF4L8V" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <header class="l-page__header"> <div class="o-header"> <div class="o-header__top"> <div class="o-header__top-contain"> <a class="o-header__parent-site-link " href="https://temertymedicine.utoronto.ca"> <svg class="o-header__parent-site-link__svg" xmlns="http://www.w3.org/2000/svg" width="8" height="12" viewBox="0 0 8 12"> <polygon points="7.2 1.426 2.89 5.801 7.2 10.241 5.871 11.667 .2 5.801 5.871 0"/> </svg> Temerty Faculty of Medicine </a> <div class="o-header__shortcuts"> <nav role="navigation" aria-labelledby="block-header-shortcuts-menu" id="block-header-shortcuts"> <h2 class="visually-hidden" id="block-header-shortcuts-menu">Header Shortcuts</h2> <ul class="m-menu-header-shortcuts"> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/contacts.htm" class="m-menu-header-shortcuts__link">Emergency</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/campuses/maps.htm" class="m-menu-header-shortcuts__link">Maps</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/" class="m-menu-header-shortcuts__link">U of T Main</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/a-z.htm" class="m-menu-header-shortcuts__link">A-Z Directory</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="/contact-us" class="m-menu-header-shortcuts__link" data-drupal-link-system-path="node/311">Contact</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="https://engage.utoronto.ca/site/SPageServer?pagename=donate#/collection/53" class="m-menu-header-shortcuts__link">Donate</a> </li> </ul> </nav> </div> <div class="o-header__search"> <a href="/search" class="a-btn-icon--sml " > <div class="a-btn-icon__icon"> <div class="a-icon--inline"> <i class="fas fa-search" data-fa-transform="" data-fa-mask="" ></i> <span class="u-visually--hidden">Search this site</span> </div> </div> </a> </div> </div> </div> <div class="o-header__bottom"> <style> .o-header__logo { width: var(--logo-width); height: var(--logo-height); } </style> <div class="o-header__logo" style="--logo-width: 375px; --logo-height: auto;"> <div class="o-header__logo-wrapper"> <a class="m-logo--image" href="/" > <img class="m-logo--image__img" src="/sites/default/files/assets/logo/DonnellyLogo.png" alt="Donnelly Centre for Cellular and Biomolecular Research Home" > </a> </div> </div> <div class="o-header__mobile-btn"> <a href="#menu-mobile" id="toggle-icon" class="0--icon-sml " > <div class="a-icon--sml"> <i class="fas fa-bars" data-fa-transform="" data-fa-mask="" ></i> <span class="u-visually--hidden">Menu</span> </div> </a> </div> </div> <div class="o-header__menu-main-wrapper"> <div class="o-header__menu-main"> <nav role="navigation" aria-labelledby="menu-main-menu" id="menu-main" data-menu-main="" class="m-menu-main"> <h2 class="visually-hidden" id="menu-main-menu">Main Menu</h2> <nav class="m-menu-main" aria-labelledby="main-nav" data-menu-main> <h2 class="u-visually--hidden" id="main-nav">Main navigation</h2> <ul class="m-menu-main__list--level-1" data-dropdown-menu role="menu"> <li class="m-menu-main__item--level-1 is-active" aria-current="page" role="menuitem"> <a href="/our-scientists" class="m-menu-main__link--level-1" data-toggle="panel-id-4cff8143-1fe6-461d-a267-7928bf4e9044" target="_self" data-drupal-link-system-path="node/398">Our Scientists</a> <div class="m-menu-main__panel" id="panel-id-4cff8143-1fe6-461d-a267-7928bf4e9044" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/faculty/brenda-andrews" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/236">Andrews, Brenda</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/stephane-angers" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/458">Angers, Stephane</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/liliana-attisano" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/240">Attisano, Liliana</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/artem-babaian" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/956">Babaian, Artem</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/gary-bader" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/235">Bader, Gary</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/benjamin-blencowe" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/241">Blencowe, Benjamin</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/charles-boone" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/239">Boone, Charles</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/grant-brown" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/242">Brown, Grant</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/warren-chan" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/244">Chan, Warren</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/andrew-fraser" title="" class="m-menu-main__link--level-2 is-active" data-drupal-link-system-path="node/238" aria-current="page">Fraser, Andrew</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/james-friesen" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/267">Friesen, James (Professor Emeritus)</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/faculty/penney-gilbert" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/247">Gilbert, Penney</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/jesse-gillis" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/495">Gillis, Jesse</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/aleksandrina-goeva" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1457">Goeva, Aleksandrina</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/jack-greenblatt" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/248">Greenblatt, Jack</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/timothy-hughes" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/233">Hughes, Timothy</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/philip-m-kim" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/249">Kim, Philip M.</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/henry-krause" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/251">Krause, Henry</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/j-rafael-montenegro-burke" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/268">Montenegro Burke, Rafael (Rafa)</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/john-morris" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1410">Morris, John</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/cindi-morshead" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/253">Morshead, Cindi</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/milica-radisic" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1056">Radisic, Milica</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/hannes-rost" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/266">Röst, Hannes</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/faculty/frederick-roth" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/255">Roth, Frederick (Fritz)</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/peter-roy" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/237">Roy, Peter</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/william-ryu" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/256">Ryu, William</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/michael-sefton" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/257">Sefton, Michael</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/molly-shoichet" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/258">Shoichet, Molly</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/igor-stagljar" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/260">Stagljar, Igor</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/mikko-taipale" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/261">Taipale, Mikko</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/derek-van-der-kooy" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/250">van der Kooy, Derek</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/shu-wang" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1346">Wang, Shu</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/aaron-wheeler" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/262">Wheeler, Aaron</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/christopher-yip" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/263">Yip, Christopher</a> </li> <li class="m-menu-main__item--level-2"> <a href="/faculty/zhaolei-zhang" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/265">Zhang, Zhaolei</a> </li> </ul> </div> </div> </div> </li> <li class="menu-firstchild m-menu-main__item--level-1" role="menuitem"> <a href="/our-research-0" class="m-menu-main__link--level-1" data-toggle="panel-id-8a720d4e-4157-4921-aaad-85f0773c5da2" target="_self">Research</a> <div class="m-menu-main__panel" id="panel-id-8a720d4e-4157-4921-aaad-85f0773c5da2" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/our-research-0" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/411">Our Research</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/pubmed" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/383">Publications (RSS feed)</a> </li> </ul> </div> </div> </div> </li> <li class="m-menu-main__item--level-1" role="menuitem"> <a href="/platforms" class="m-menu-main__link--level-1" data-toggle="panel-id-5632f555-87dc-4249-8cd4-9eb20af82d39" target="_self" data-drupal-link-system-path="node/402">Platforms</a> <div class="m-menu-main__panel" id="panel-id-5632f555-87dc-4249-8cd4-9eb20af82d39" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/accelerator-donnelly-collaboration" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/376">Accelerator for Donnelly Collaboration</a> </li> <li class="m-menu-main__item--level-2"> <a href="/donnelly-mass-spec-facility" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/364">Donnelly Mass Spec Facility</a> </li> </ul> </div> <div class="m-menu-main__col--2-split is-split"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-sequencing-centre" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/307">Donnelly Sequencing Centre</a> <ul class="m-menu-main__list--level-3" data-main-menu-component="third-level-list"> <li class="m-menu-main__item--level-3"> <a href="/what-we-offer" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/365">What We Offer</a> </li> <li class="m-menu-main__item--level-3"> <a href="/getting-started" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/366">Getting Started</a> </li> <li class="m-menu-main__item--level-3"> <a href="/dsc-team" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/367">The DSC Team</a> </li> <li class="m-menu-main__item--level-3"> <a href="/selected-publications" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/368">Publications</a> </li> <li class="m-menu-main__item--level-3"> <a href="/academic-outreach" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/369">Academic Outreach</a> </li> <li class="m-menu-main__item--level-3"> <a href="/world-sequencing" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/371">The World of Sequencing</a> </li> </ul> </li> </ul> </div> </div> </div> </li> <li class="m-menu-main__item--level-1" role="menuitem"> <a href="/students" class="m-menu-main__link--level-1" data-toggle="panel-id-6e23f8a3-370d-4590-9de5-263641ef521c" target="_self" data-drupal-link-system-path="node/401">Students</a> <div class="m-menu-main__panel" id="panel-id-6e23f8a3-370d-4590-9de5-263641ef521c" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/student-awards" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/294">Student Awards</a> <ul class="m-menu-main__list--level-3" data-main-menu-component="third-level-list"> <li class="m-menu-main__item--level-3"> <a href="/cecil-yip-doctoral-research-award" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/297">Cecil Yip Doctoral Research Award</a> </li> <li class="m-menu-main__item--level-3"> <a href="/donnelly-centre-research-thesis-prize" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/298">Donnelly Centre Research Thesis Prize</a> </li> <li class="m-menu-main__item--level-3"> <a href="/jennifer-comyn-graduate-award-cancer-research" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/1244">Jennifer Comyn Graduate Award for Cancer Research</a> </li> <li class="m-menu-main__item--level-3"> <a href="/jennifer-dorrington-graduate-research-award" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/296">Jennifer Dorrington Graduate Research Award</a> </li> </ul> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-centre-graduate-student-association" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/326">Donnelly Centre Graduate Student Association</a> </li> <li class="m-menu-main__item--level-2"> <a href="/summer-undergraduate-research-program" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/355">Summer Undergraduate Research Program</a> <ul class="m-menu-main__list--level-3" data-main-menu-component="third-level-list"> <li class="m-menu-main__item--level-3"> <a href="/donnelly-centre-summer-student-research-award" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/1358">Donnelly Centre Summer Student Research Award</a> </li> </ul> </li> </ul> </div> </div> </div> </li> <li class="m-menu-main__item--level-1" role="menuitem"> <a href="/postdocs" class="m-menu-main__link--level-1" data-toggle="panel-id-1e61f096-d39c-4ca8-ab30-be9aa290d6b7" target="_self" data-drupal-link-system-path="node/403">Postdocs</a> <div class="m-menu-main__panel" id="panel-id-1e61f096-d39c-4ca8-ab30-be9aa290d6b7" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/charles-h-best-postdoctoral-fellowship" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/295">Charles H. Best Postdoctoral Fellowship</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-centre-home-fellowship" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1353">Donnelly Centre Home Fellowship</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-centre-research-excellence-award" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/356">Donnelly Centre Research Excellence Award</a> </li> </ul> </div> </div> </div> </li> <li class="menu-firstchild m-menu-main__item--level-1" role="menuitem"> <a href="/news" class="m-menu-main__link--level-1" data-toggle="panel-id-34d84ee5-3d4f-4534-a22d-e080da4d77c9" target="_self">News</a> <div class="m-menu-main__panel" id="panel-id-34d84ee5-3d4f-4534-a22d-e080da4d77c9" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/news" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/381">News</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-centre-magazine" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/374">Donnelly Centre Magazine</a> </li> <li class="m-menu-main__item--level-2"> <a href="/annual-reports" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/400">Annual Reports</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/donnelly-media" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/316">Donnelly in the Media</a> <ul class="m-menu-main__list--level-3" data-main-menu-component="third-level-list"> <li class="m-menu-main__item--level-3"> <a href="/media-archive-2008-2020" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/426">In the Media Archive (2008-2020)</a> </li> </ul> </li> </ul> </div> </div> </div> </li> <li class="menu-firstchild m-menu-main__item--level-1" role="menuitem"> <a href="/current-opportunities" class="m-menu-main__link--level-1" data-toggle="panel-id-7fb1f7dd-f886-43c5-8fcc-0b45e53044a4" target="_self">Careers</a> <div class="m-menu-main__panel" id="panel-id-7fb1f7dd-f886-43c5-8fcc-0b45e53044a4" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/current-opportunities" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/283">Current Opportunities</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/working-and-living-toronto" title="" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/299">Working and Living in Toronto</a> </li> </ul> </div> </div> </div> </li> <li class="m-menu-main__item--level-1" role="menuitem"> <a href="/events" class="m-menu-main__link--level-1" data-toggle="panel-id-4b4b688a-2197-48a8-a290-e9661bfaf496" target="_self" data-drupal-link-system-path="node/1249">Events</a> <div class="m-menu-main__panel" id="panel-id-4b4b688a-2197-48a8-a290-e9661bfaf496" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/events" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/1249">Events</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/postdoctoral-fellow-and-research-associate-seminars" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/323">Postdoctoral Fellow and Research Associate Seminars</a> </li> </ul> </div> </div> </div> </li> <li class="menu-firstchild m-menu-main__item--level-1" role="menuitem"> <a href="/welcome-director" class="m-menu-main__link--level-1" data-toggle="panel-id-3fc7b65c-6bbe-4949-95b8-ff98c92c665f" target="_self">About Us</a> <div class="m-menu-main__panel" id="panel-id-3fc7b65c-6bbe-4949-95b8-ff98c92c665f" data-dropdown data-close-on-click="true" data-hover="true" data-hover-pane="true"> <div class="m-menu-main__cols--3"> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/welcome-director" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/455">Director's Welcome Message</a> </li> <li class="m-menu-main__item--level-2"> <a href="/terrence-j-donnelly" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/304">Terrence J. Donnelly</a> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/built-21st-century-science" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/285">History of the Donnelly Centre</a> <ul class="m-menu-main__list--level-3" data-main-menu-component="third-level-list"> <li class="m-menu-main__item--level-3"> <a href="/banting-and-best-department-medical-research-timeline" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/347">Get to know our history through this interactive timeline</a> </li> <li class="m-menu-main__item--level-3"> <a href="/banting-and-best-department-medical-research" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/344">Banting and Best Department of Medical Research</a> </li> <li class="m-menu-main__item--level-3"> <a href="/brenda-andrews-founding-director-donnelly-centre" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/476">Brenda Andrews, Founding Director of Donnelly Centre</a> </li> <li class="m-menu-main__item--level-3"> <a href="/james-friesen-co-founder-donnelly-centre" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/348">James Friesen, Co-Founder of Donnelly Centre</a> </li> <li class="m-menu-main__item--level-3"> <a href="/cecil-yip-co-founder-donnelly-centre" class="m-menu-main__link--level-3" target="_self" data-drupal-link-system-path="node/346">Cecil Yip, Co-Founder of Donnelly Centre</a> </li> </ul> </li> </ul> </div> <div class="m-menu-main__col--"> <ul class="m-menu-main__list--level-2" data-main-menu-component="second-level-list"> <li class="m-menu-main__item--level-2"> <a href="/staff" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/305">Staff</a> </li> <li class="m-menu-main__item--level-2"> <a href="/image-gallery" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/328">Image Gallery</a> </li> <li class="m-menu-main__item--level-2"> <a href="/contact-us" class="m-menu-main__link--level-2" data-drupal-link-system-path="node/311">Contact Us</a> </li> </ul> </div> </div> </div> </li> </ul> </nav> </nav> </div> </div> </div> </header> <main class="l-page__main"> <div class="l-main-2col"> <div class="l-main-2col__content-wrapper"> <div class="l-main-2col__aside" data-sticky-sidebar-container> <div data-sticky-sidebar-sidebar> <div data-sticky-sidebar-inner> <nav class="m-menu-side" role="navigation" aria-labelledby="block-main-second-level-menu" id="block-main-second-level"> <h2 class="visually-hidden" id="block-main-second-level-menu">Main Second Level Navigation</h2> <ul class="m-menu-side__list--level-1"> <li class="m-menu-side__item--level-1"> <a href="/faculty/brenda-andrews" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/236">Andrews, Brenda</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/stephane-angers" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/458">Angers, Stephane</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/liliana-attisano" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/240">Attisano, Liliana</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/artem-babaian" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/956">Babaian, Artem</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/gary-bader" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/235">Bader, Gary</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/benjamin-blencowe" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/241">Blencowe, Benjamin</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/charles-boone" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/239">Boone, Charles</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/grant-brown" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/242">Brown, Grant</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/warren-chan" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/244">Chan, Warren</a> </li> <li class="m-menu-side__item--level-1 is-active"> <a href="/faculty/andrew-fraser" title="" class="m-menu-side__link--level-1 is-active" data-drupal-link-system-path="node/238" aria-current="page">Fraser, Andrew</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/james-friesen" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/267">Friesen, James (Professor Emeritus)</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/penney-gilbert" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/247">Gilbert, Penney</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/jesse-gillis" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/495">Gillis, Jesse</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/aleksandrina-goeva" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/1457">Goeva, Aleksandrina</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/jack-greenblatt" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/248">Greenblatt, Jack</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/timothy-hughes" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/233">Hughes, Timothy</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/philip-m-kim" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/249">Kim, Philip M.</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/henry-krause" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/251">Krause, Henry</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/j-rafael-montenegro-burke" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/268">Montenegro Burke, Rafael (Rafa)</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/john-morris" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/1410">Morris, John</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/cindi-morshead" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/253">Morshead, Cindi</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/milica-radisic" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/1056">Radisic, Milica</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/hannes-rost" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/266">Röst, Hannes</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/frederick-roth" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/255">Roth, Frederick (Fritz)</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/peter-roy" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/237">Roy, Peter</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/william-ryu" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/256">Ryu, William</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/michael-sefton" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/257">Sefton, Michael</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/molly-shoichet" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/258">Shoichet, Molly</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/igor-stagljar" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/260">Stagljar, Igor</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/mikko-taipale" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/261">Taipale, Mikko</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/derek-van-der-kooy" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/250">van der Kooy, Derek</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/shu-wang" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/1346">Wang, Shu</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/aaron-wheeler" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/262">Wheeler, Aaron</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/christopher-yip" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/263">Yip, Christopher</a> </li> <li class="m-menu-side__item--level-1"> <a href="/faculty/zhaolei-zhang" title="" class="m-menu-side__link--level-1" data-drupal-link-system-path="node/265">Zhang, Zhaolei</a> </li> </ul> </nav> </div> </div> </div> <a class="l-main__a11y-jump" id="main-content" tabindex="-1"></a> <div class="l-main-2col__breadcrumbs"> <div class="m-breadcrumbs__wrapper"> <nav role="navigation" aria-labelledby="system-breadcrumb" class="m-breadcrumbs"> <h2 class="visually-hidden" id="system-breadcrumb">Breadcrumbs</h2> <ol class="m-breadcrumbs__list"> <li class="m-breadcrumbs__item"> <a class="m-breadcrumbs__link" href="/">Home</a> </li> <li class="m-breadcrumbs__item"> <a class="m-breadcrumbs__link" href="/our-scientists">Our Scientists</a> </li> <li class="m-breadcrumbs__item"> Fraser, Andrew </li> </ol> </nav> </div> </div> <div class="l-main-2col__utility"> <div data-drupal-messages-fallback class="hidden"></div> </div> <div class="l-main-2col__content"> <div class="l-main__header-prefix"> <div class="l-main__fac-pretitle"> <span> Professor | Principal Investigator </span> </div> </div> <div class="o-content-header"> <h1 class="a-heading__t1 " > Andrew Fraser </h1> <div class="o-content-header__post-title"> Department of Molecular Genetics </div> <div class="o-content-header__subtitle"> <h2>PhD</h2> </div> </div> <div class="l-main__fac-info has-img"> <div class="l-main__fac-image"> <picture> <source srcset="/sites/default/files/styles/square_1_1_200/public/assets/faculty/image/HPOT2638lr.webp?itok=mt1Ixh4Z 200w, /sites/default/files/styles/square_1_1_400/public/assets/faculty/image/HPOT2638lr.webp?itok=EkeXHwWj 400w, /sites/default/files/styles/square_1_1_600/public/assets/faculty/image/HPOT2638lr.webp?itok=iPSjPTsh 600w, /sites/default/files/styles/square_1_1_900/public/assets/faculty/image/HPOT2638lr.webp?itok=nrS2UJea 900w, /sites/default/files/styles/square_1_1_1200/public/assets/faculty/image/HPOT2638lr.webp?itok=C6TlB-Z9 1200w, /sites/default/files/styles/square_1_1_1500/public/assets/faculty/image/HPOT2638lr.webp?itok=YyqbzKZb 1500w, /sites/default/files/styles/square_1_1_1800/public/assets/faculty/image/HPOT2638lr.webp?itok=hgCrYNPg 1800w, /sites/default/files/styles/square_1_1_2000/public/assets/faculty/image/HPOT2638lr.webp?itok=a3ZDSs9r 2000w, /sites/default/files/styles/square_1_1_2500/public/assets/faculty/image/HPOT2638lr.webp?itok=vICYQmps 2500w, /sites/default/files/styles/square_1_1_2800/public/assets/faculty/image/HPOT2638lr.webp?itok=uAbUb2Ns 2800w, /sites/default/files/styles/square_1_1_3000/public/assets/faculty/image/HPOT2638lr.webp?itok=ioCrjG2k 3000w" type="image/webp" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="900"/> <source srcset="/sites/default/files/styles/square_1_1_200/public/assets/faculty/image/HPOT2638lr.jpg?itok=mt1Ixh4Z 200w, /sites/default/files/styles/square_1_1_400/public/assets/faculty/image/HPOT2638lr.jpg?itok=EkeXHwWj 400w, /sites/default/files/styles/square_1_1_600/public/assets/faculty/image/HPOT2638lr.jpg?itok=iPSjPTsh 600w, /sites/default/files/styles/square_1_1_900/public/assets/faculty/image/HPOT2638lr.jpg?itok=nrS2UJea 900w, /sites/default/files/styles/square_1_1_1200/public/assets/faculty/image/HPOT2638lr.jpg?itok=C6TlB-Z9 1200w, /sites/default/files/styles/square_1_1_1500/public/assets/faculty/image/HPOT2638lr.jpg?itok=YyqbzKZb 1500w, /sites/default/files/styles/square_1_1_1800/public/assets/faculty/image/HPOT2638lr.jpg?itok=hgCrYNPg 1800w, /sites/default/files/styles/square_1_1_2000/public/assets/faculty/image/HPOT2638lr.jpg?itok=a3ZDSs9r 2000w, /sites/default/files/styles/square_1_1_2500/public/assets/faculty/image/HPOT2638lr.jpg?itok=vICYQmps 2500w, /sites/default/files/styles/square_1_1_2800/public/assets/faculty/image/HPOT2638lr.jpg?itok=uAbUb2Ns 2800w, /sites/default/files/styles/square_1_1_3000/public/assets/faculty/image/HPOT2638lr.jpg?itok=ioCrjG2k 3000w" type="image/jpeg" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="900"/> <img loading="lazy" srcset="/sites/default/files/styles/square_1_1_200/public/assets/faculty/image/HPOT2638lr.jpg?itok=mt1Ixh4Z 200w, /sites/default/files/styles/square_1_1_400/public/assets/faculty/image/HPOT2638lr.jpg?itok=EkeXHwWj 400w, /sites/default/files/styles/square_1_1_600/public/assets/faculty/image/HPOT2638lr.jpg?itok=iPSjPTsh 600w, /sites/default/files/styles/square_1_1_900/public/assets/faculty/image/HPOT2638lr.jpg?itok=nrS2UJea 900w, /sites/default/files/styles/square_1_1_1200/public/assets/faculty/image/HPOT2638lr.jpg?itok=C6TlB-Z9 1200w, /sites/default/files/styles/square_1_1_1500/public/assets/faculty/image/HPOT2638lr.jpg?itok=YyqbzKZb 1500w, /sites/default/files/styles/square_1_1_1800/public/assets/faculty/image/HPOT2638lr.jpg?itok=hgCrYNPg 1800w, /sites/default/files/styles/square_1_1_2000/public/assets/faculty/image/HPOT2638lr.jpg?itok=a3ZDSs9r 2000w, /sites/default/files/styles/square_1_1_2500/public/assets/faculty/image/HPOT2638lr.jpg?itok=vICYQmps 2500w, /sites/default/files/styles/square_1_1_2800/public/assets/faculty/image/HPOT2638lr.jpg?itok=uAbUb2Ns 2800w, /sites/default/files/styles/square_1_1_3000/public/assets/faculty/image/HPOT2638lr.jpg?itok=ioCrjG2k 3000w" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="900" src="/sites/default/files/styles/square_1_1_600/public/assets/faculty/image/HPOT2638lr.jpg?itok=iPSjPTsh" alt="Headshot of Andrew Fraser" typeof="foaf:Image" /> </picture> </div> <div class="l-main__fac-links"> <div class="m-text-icon"> <div class='m-text-icon__heading'> <div class="m-text-icon__icon"> <div class="a-icon--xsml"> <i class="fas fa-envelope" data-fa-transform="" data-fa-mask="" ></i> </div> </div> <div class="m-text-icon--simple-text__title"> <h2 class="a-heading__h4 has-link " > <a href="mailto:andyfraser.utoronto@gmail.com" > <span class="a-heading__last-word">andyfraser.utoronto@gmail.com <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> </div> </div> <div class="m-text-icon"> <div class='m-text-icon__heading'> <div class="m-text-icon__icon"> <div class="a-icon--xsml"> <i class="fas fa-phone-alt" data-fa-transform="" data-fa-mask="" ></i> </div> </div> <div class="m-text-icon--simple-text__title"> <h2 class="a-heading__h4 has-link " > <a href="tel:(416) 978-2712" > (416) <span class="a-heading__last-word">978-2712 <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> </div> </div> <div class="m-text-icon"> <div class='m-text-icon__heading'> <div class="m-text-icon__icon"> <div class="a-icon--xsml"> <i class="fas fa-external-link-alt" data-fa-transform="" data-fa-mask="" ></i> </div> </div> <div class="m-text-icon--simple-text__title"> <h2 class="a-heading__h4 has-link " > <a href="http://www.fraserlab.org/" > <span class="a-heading__last-word">Website <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> </div> </div> <div class="m-text-icon"> <div class='m-text-icon__heading'> <div class="m-text-icon__icon"> <div class="a-icon--xsml"> <i class="fas fa-link" data-fa-transform="" data-fa-mask="" ></i> </div> </div> <div class="m-text-icon--simple-text__title"> <h2 class="a-heading__h4 has-link " > <a href="https://pubmed.ncbi.nlm.nih.gov/?term=Fraser%20AG%5BAuthor%5D" > <span class="a-heading__last-word">Publications <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> </div> </div> </div> </div> <div class="l-main__fac-location"> <div class="m-listing-item-text"> <div class="m-listing-item-text__title">Address</div> <div class="m-listing-item-text__text">Room 1212</div> </div> <div class="m-listing-item-text"> <div class="m-listing-item-text__title">Research Interests</div> <div class="m-listing-item-text__text">Systematic Genetics, Mendelian Disorders, Genetic Interactions, Drug Screens, Evo-Devo</div> </div> <div class="m-listing-item-text"> <div class="m-listing-item-text__title">Appointment Status</div> <div class="m-listing-item-text__text">Primary</div> </div> </div> <div class="l-main__fac-qualifications"> <h2 class="a-type__h4"> Qualification</h2> <ul class="a-list--unordered"> <li>University of Cambridge, Gurdon Institute, U.K., Research Fellow, 1999-2003.</li> <li>Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, U.S., Research Fellow, 1997-1999.</li> <li>Imperial Cancer Research Fund, London, U.K., PhD in cancer biology, 1993-1997.</li> <li>University of Cambridge,U.K., BA in Biochemistry and Molecular Biology, 1990-1993.</li> </ul> </div> <div class="l-main__fac-profile"> <div data-webpack-readmore data-collapsed-height="832" data-offset-height="128" data-more-text="Read more"> <div class="s-wysiwyg"><h3 class="a-heading__h3"><strong>MY RESEARCH OVERVIEW (GO TO <a href="#genetics">SCIENTIFIC OVERVIEW</a>)</strong></h3> <h4 class="a-heading__h4">The worm — a simpler, more elegant human</h4> <p>In any bar, if I tell people that I work on worms their eyes glaze over. When I say I’ve been doing that for ten years and more, I get looks of pity. If I ever go on to say that I think worms are totally cool, like humans only simpler and easier, then people edge away quietly leaving me alone with my beer. So why do I work on this tiny animal?</p> <p></p><figure class="align-right"> <img alt="STUDYING THE EFFECT OF DISEASE-CAUSING GENES IN WORMS" data-entity-type="file" data-entity-uuid="812612da-807c-4164-9ac8-846b9d627769" src="/sites/default/files/inline-images/andy_image.jpg"> <figcaption>STUDYING THE EFFECT OF DISEASE-CAUSING GENES IN WORMS</figcaption> </figure> <p>I work on worms because I like simple, stripped-down models that I can play with easily. The worm is very basic — each adult has only 959 cells and we know every cell division that occurs during its development. Despite its simplicity of form, the worm is genetically complex — the worm has 20,000 genes, half of which have very close matches in humans. So here’s the problem: we know all the genes and we know the whole of development — what does each gene do and how do they all cooperate to make a correct functioning animal? And here’s the magic — using a technique called RNAi, we can switch off any one of the worm’s genes at any stage of development and look at the effect on the animal. RNAi is miraculously easy to carry out, and so we can play with the worm simply and quickly, taking out the 20,000 genes one by one and looking at the effects.</p> <p>Ultimately, fun as it is to mess around with worms, what we care about is humans. The central question that interests us is this — if you knew your entire genome sequence, what would it tell you? Can you predict your chances of getting bowel cancer, or of having an adverse reaction to a drug? At present, the answer is an emphatic no. How does our work in the worm help with this problem? In the worm, since we can use RNAi to remove each gene in turn and see the precise effect on the ‘health’ of the worm, we can begin to learn how to predict how inherited mutations will affect health in humans. We study not only how to predict the effect of removing any individual gene (which we can now do with surprising accuracy), but also the effect of removing combinations of genes. Since there are ~3million differences between any human genomes, knowing how multiple mutations combine to affect our health and risk of disease is one of the major problems in modern genetics.<br> </p> <h3 class="a-heading__h3"><strong>SCIENTIFIC RESEARCH OVERVIEW</strong></h3> <p>Mendelian disorders like cystic fibrosis and sickle cell anaemia are the best understood human genetic diseases. They are genetically very simple — the inheritance of a single mutated gene causes each disorder. We now know many hundreds of these disease-causing mutations — each mutation is rare, and each causes a single specific disorder, but together they make a major impact on human disease. At first sight, Mendelian disorders are hard to tackle — different genes are mutated in different disorders and each disorder is rare. How can we deal with all this genetic variation and all these rare disorders?</p> <p>We want to understand the basic principles underlying ALL Mendelian disorders rather than dissect any single one exhaustively. In particular we are interested in one common feature of all Mendelian disorders — that while two people inheriting an identical mutation get the same disorder, they often have very different severity of symptoms. This range of symptoms can be extreme — one person can die yet another with the same genetic error can be almost completely healthy. If we can learn what is the genetic basis for the differences in severity of Mendelian disorders between any two people, we can give much more accurate and personalized diagnoses and also potentially develop new therapies aimed at regulating severity.</p> <p>Our approach to this complex problem is to try to solve it in a simple system — the nematode worm <em>C.elegans</em>. The genetic tools in the worm are extremely powerful and the biology of the worm is almost completely defined. We can knock down, knock out, or mutate any gene in any individual worm and quantify precise effects on phenotype using assays that we have built. In broadest outline, if we could understand what determines the severity of a worm ‘Mendelian disorder’, we could apply these insights to human Mendelian disorders. We have already done a major project comparing mutant phenotypes of 1400 genes between two individuals using RNA-mediated interference (RNAi) and this study identified key effects of natural variation in gene expression on mutant phenotypes. In the future, we intend to extend this to a further 10 individuals using CRISPR-based approaches, RNAi screening and drug based screening. In addition, we will map many of the variants that affect the severity of genetic disorders in the worm. Together, this will be the first comprehensive view of how the same genetic perturbation can differ between individuals for any species and we are collaborating with several clinical and human genomics groups to take our findings into human samples.</p> <p>Our programme to use the power of systematic genetics in <em>C. elegans</em> to understand the basic principles underlying human Mendelian disorders combines quantitative biology, computational biology, and human genetics. We believe it addresses one of the most fundamental aspects of human genetic disease — not to identify which mutations affect the health of humans in general, but to understand the effect of any mutation on a single affected human.</p> <h4 class="a-heading__h4"><strong>SELECT PUBLICATIONS</strong></h4> <blockquote> <ul> <li><a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=26186192"><em>Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes</em></a>. Vu V, Verster AJ, Schertzberg M, Chuluunbaatar T, Spensley M, Pajkic D, Hart GT, Moffat J, Fraser AG. <strong>Cell</strong>. 2015 Jul 16;162(2):391-402.</li> <li><a href="http://www.ncbi.nlm.nih.gov/pubmed/22341449"><em>The majority of animal genes are required for wild-type fitness</em></a>. Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. <strong>Cell</strong>. 2012 Feb 17;148(4):792-802.</li> <li> <p><a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=24516395"><em>Comparative RNAi screens in C. elegans and C. briggsae reveal the impact of developmental system drift on gene function</em></a>. Verster AJ, Ramani AK, McKay SJ, Fraser AG. <strong>PLoS Genet</strong>. 2014 Feb 6.</p> </li> </ul> </blockquote></div> </div> </div> <div class="l-main__fac-pager"> <ul class="prev-next-wrapper"> <li class="prev-next-previous prev-next-item"> <a class="a-btn" href="/faculty/warren-chan"> <i class="prev-next-item__icon fas fa-chevron-left"></i> Previous </a> </li> <li class="prev-next-next prev-next-item"> <a class="a-btn" href="/faculty/james-friesen"> Next <i class="prev-next-item__icon fas fa-chevron-right"></i> </a> </li> </ul> </div> </div> </div> </div> </main> <footer class="l-page__footer"> <div class="o-site-footer"> <div class="o-site-footer__main o-site-footer__main-default"> <div class="o-site-footer__address"> Donnelly Centre for Cellular and Biomolecular Research<br> University of Toronto 160 College Street, Room 230,<br> Toronto, Ontario CANADA M5S 3E1<br> Tel: (416) 978-8861 Fax: (416) 978-8287 </div> <nav class="o-site-footer__links"> <div class="o-site-footer__social"> <a href="https://www.linkedin.com/company/donnelly-centre-for-cellular-and-biomolecular-research/" target="_blank" class="a-btn--icon " > <div class="a-icon"> <i class="fab fa-linkedin" data-fa-transform="" data-fa-mask="" ></i> <span class="u-visually--hidden">Follow us on LinkedIn</span> </div> </a> <a href="https://twitter.com/DonnellyCentre" target="_blank" class="a-btn--icon " > <div class="a-icon"> <i class="fab fa-square-x-twitter" data-fa-transform="" data-fa-mask="" ></i> <span class="u-visually--hidden">Follow us on Twitter</span> </div> </a> <a href="https://www.youtube.com/playlist?list=PLEfWVIQeGAodxdY2TZpmVVwlOKcweoteW" target="_blank" class="a-btn--icon " > <div class="a-icon"> <i class="fab fa-youtube-square" data-fa-transform="" data-fa-mask="" ></i> <span class="u-visually--hidden">Follow us on Youtube</span> </div> </a> </div> <div class="o-site-footer__acknowledge"> <a href="https://indigenous.utoronto.ca/about/land-acknowledgement" class="a-link--white " > <span class="a-link__text">Traditional Land Acknowledgement</span> </a> </div> </nav> </div> <div class="o-site-footer__shortcuts"> <nav role="navigation" aria-labelledby="block-header-shortcuts-menu" id="block-header-shortcuts"> <h2 class="visually-hidden" id="block-header-shortcuts-menu">Header Shortcuts</h2> <ul class="m-menu-header-shortcuts"> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/contacts.htm" class="m-menu-header-shortcuts__link">Emergency</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/campuses/maps.htm" class="m-menu-header-shortcuts__link">Maps</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/" class="m-menu-header-shortcuts__link">U of T Main</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="http://www.utoronto.ca/a-z.htm" class="m-menu-header-shortcuts__link">A-Z Directory</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="/contact-us" class="m-menu-header-shortcuts__link" data-drupal-link-system-path="node/311">Contact</a> </li> <li class="m-menu-header-shortcuts__item"> <a href="https://engage.utoronto.ca/site/SPageServer?pagename=donate#/collection/53" class="m-menu-header-shortcuts__link">Donate</a> </li> </ul> </nav> </div> <div class="o-site-footer__bottom-wrapper"> <div class="o-site-footer__bottom "> <div class="o-site-footer__legal"> © 2024 University of Toronto</div> <div class="o-site-footer__logo"> <img class="m-logo--image__img" src="/themes/webpac//images/icons/temerty-medicine-wordmark-coloured.svg" alt="Visit Termerty Faculty of Medicine Home" width="505" height="120" > </div> </div> </div> </div> </footer> <nav role="navigation" aria-labelledby="menu-mobile-menu" id="menu-mobile" data-menu-mobile="" class="m-menu-mobile"> <h2 class="visually-hidden" id="menu-mobile-menu">Mobile Menu</h2> <nav class="m-menu-mobile" id="menu-mobile" role="navigation" aria-labelledby="mobile-nav" data-menu-mobile> <h2 class="u-visually--hidden" id="mobile-nav">Mobile navigation</h2> <ul class="m-menu-mobile__list--level-1"> <li class="m-menu-mobile__item--level-1 is-active has-submenu"> <a href="/our-scientists" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/398">Our Scientists</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/brenda-andrews" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/236">Andrews, Brenda</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/stephane-angers" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/458">Angers, Stephane</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/liliana-attisano" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/240">Attisano, Liliana</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/artem-babaian" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/956">Babaian, Artem</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/gary-bader" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/235">Bader, Gary</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/benjamin-blencowe" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/241">Blencowe, Benjamin</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/charles-boone" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/239">Boone, Charles</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/grant-brown" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/242">Brown, Grant</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/warren-chan" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/244">Chan, Warren</a> </li> <li class="m-menu-mobile__item--level-2 is-active"> <a href="/faculty/andrew-fraser" title="" class="m-menu-mobile__link--level-2 is-active" data-drupal-link-system-path="node/238" aria-current="page">Fraser, Andrew</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/james-friesen" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/267">Friesen, James (Professor Emeritus)</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/penney-gilbert" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/247">Gilbert, Penney</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/jesse-gillis" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/495">Gillis, Jesse</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/aleksandrina-goeva" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1457">Goeva, Aleksandrina</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/jack-greenblatt" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/248">Greenblatt, Jack</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/timothy-hughes" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/233">Hughes, Timothy</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/philip-m-kim" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/249">Kim, Philip M.</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/henry-krause" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/251">Krause, Henry</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/j-rafael-montenegro-burke" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/268">Montenegro Burke, Rafael (Rafa)</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/john-morris" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1410">Morris, John</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/cindi-morshead" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/253">Morshead, Cindi</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/milica-radisic" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1056">Radisic, Milica</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/hannes-rost" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/266">Röst, Hannes</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/frederick-roth" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/255">Roth, Frederick (Fritz)</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/peter-roy" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/237">Roy, Peter</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/william-ryu" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/256">Ryu, William</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/michael-sefton" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/257">Sefton, Michael</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/molly-shoichet" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/258">Shoichet, Molly</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/igor-stagljar" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/260">Stagljar, Igor</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/mikko-taipale" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/261">Taipale, Mikko</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/derek-van-der-kooy" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/250">van der Kooy, Derek</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/shu-wang" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1346">Wang, Shu</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/aaron-wheeler" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/262">Wheeler, Aaron</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/christopher-yip" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/263">Yip, Christopher</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/zhaolei-zhang" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/265">Zhang, Zhaolei</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/our-research-0" class="m-menu-mobile__link--level-1 is-toggle">Research</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/our-research-0" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/411">Our Research</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/pubmed" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/383">Publications (RSS feed)</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/platforms" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/402">Platforms</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/accelerator-donnelly-collaboration" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/376">Accelerator for Donnelly Collaboration</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/donnelly-sequencing-centre" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/307">Donnelly Sequencing Centre</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/what-we-offer" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/365">What We Offer</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/getting-started" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/366">Getting Started</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/dsc-team" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/367">The DSC Team</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/selected-publications" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/368">Publications</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/academic-outreach" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/369">Academic Outreach</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/world-sequencing" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/371">The World of Sequencing</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-mass-spec-facility" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/364">Donnelly Mass Spec Facility</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/students" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/401">Students</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/student-awards" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/294">Student Awards</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/cecil-yip-doctoral-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/297">Cecil Yip Doctoral Research Award</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/donnelly-centre-research-thesis-prize" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/298">Donnelly Centre Research Thesis Prize</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/jennifer-comyn-graduate-award-cancer-research" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/1244">Jennifer Comyn Graduate Award for Cancer Research</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/jennifer-dorrington-graduate-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/296">Jennifer Dorrington Graduate Research Award</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-graduate-student-association" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/326">Donnelly Centre Graduate Student Association</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/summer-undergraduate-research-program" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/355">Summer Undergraduate Research Program</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/donnelly-centre-summer-student-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/1358">Donnelly Centre Summer Student Research Award</a> </li> </ul> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/postdocs" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/403">Postdocs</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/charles-h-best-postdoctoral-fellowship" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/295">Charles H. Best Postdoctoral Fellowship</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-home-fellowship" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1353">Donnelly Centre Home Fellowship</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-research-excellence-award" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/356">Donnelly Centre Research Excellence Award</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/news" class="m-menu-mobile__link--level-1 is-toggle">News</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/news" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/381">News</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-magazine" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/374">Donnelly Centre Magazine</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/annual-reports" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/400">Annual Reports</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/donnelly-media" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/316">Donnelly in the Media</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/media-archive-2008-2020" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/426">In the Media Archive (2008-2020)</a> </li> </ul> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/current-opportunities" class="m-menu-mobile__link--level-1 is-toggle">Careers</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/current-opportunities" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/283">Current Opportunities</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/working-and-living-toronto" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/299">Working and Living in Toronto</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/events" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/1249">Events</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/events" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1249">Events</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/postdoctoral-fellow-and-research-associate-seminars" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/323">Postdoctoral Fellow and Research Associate Seminars</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/welcome-director" class="m-menu-mobile__link--level-1 is-toggle">About Us</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/welcome-director" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/455">Director's Welcome Message</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/terrence-j-donnelly" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/304">Terrence J. Donnelly</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/built-21st-century-science" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/285">History of the Donnelly Centre</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/banting-and-best-department-medical-research-timeline" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/347">Get to know our history through this interactive timeline</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/banting-and-best-department-medical-research" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/344">Banting and Best Department of Medical Research</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/brenda-andrews-founding-director-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/476">Brenda Andrews, Founding Director of Donnelly Centre</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/james-friesen-co-founder-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/348">James Friesen, Co-Founder of Donnelly Centre</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/cecil-yip-co-founder-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/346">Cecil Yip, Co-Founder of Donnelly Centre</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/staff" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/305">Staff</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/image-gallery" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/328">Image Gallery</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/contact-us" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/311">Contact Us</a> </li> </ul> </li> <div id="menu-mobile-header-content"> <div class="m-menu-mobile__header-content"> </div> </div> </ul> </nav> </nav> </div> <script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({"drupalLanguage":"en","drupalCountry":null,"siteName":"Donnelly Centre for Cellular and Biomolecular Research","entityName":"migrate","entityType":"node","entityBundle":"wp_faculty","entityId":"238","entityTitle":"Andrew Fraser","userUid":0,"breadcrumbLevel1":"Our Scientists","breadcrumbLevel2":"Fraser, Andrew","breadcrumbLevel3":""});</script> <link rel="stylesheet" href="https://use.typekit.net/zls1oah.css"> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/238","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJx9j1EKAyEMRC8keiSJmnWlMVlM7LK3r5RCSz_27zETMjNphjR93jE_cLgMizaauocv-o48XZ5q0iOU3jh0aGzIwBkji7WM6goYEFw4QsIdnk2Guq2RLSHDYU3YbcIGJ6p0DD_s9Vl9GsBFb09UqBVXRSphBAa6VrKGf8HppYY9JFB0J6YD8no1eRVcJWIZchQ5-caK78Ufv5IkoBdEPnSX","theme":"webpac","theme_token":null},"ajaxTrustedUrl":[],"bu":{"_core":{"default_config_hash":"AblkqYHezKA1TuKStbuiQqvACikY5ElI-bHxMy-C25U"},"notify_ie":11,"notify_firefox":-2,"notify_opera":-2,"notify_safari":-2,"notify_chrome":-2,"insecure":false,"unsupported":false,"mobile":false,"visibility_type":"hide","visibility_pages":"admin\/*","source":"\/\/browser-update.org\/update.min.js","show_source":"","position":"top","text_override":"","reminder":4380,"reminder_closed":4380,"new_window":true,"url":"","no_close":false,"test_mode":false},"dataLayer":{"defaultLang":"en","languages":{"en":{"id":"en","name":"English","direction":"ltr","weight":0}}},"google_analytics":{"account":"UA-34496632-11","trackOutbound":true,"trackMailto":true,"trackTel":true,"trackDownload":true,"trackDownloadExtensions":"7z|aac|arc|arj|asf|asx|avi|bin|csv|doc(x|m)?|dot(x|m)?|exe|flv|gif|gz|gzip|hqx|jar|jpe?g|js|mp(2|3|4|e?g)|mov(ie)?|msi|msp|pdf|phps|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|sea|sit|tar|tgz|torrent|txt|wav|wma|wmv|wpd|xls(x|m|b)?|xlt(x|m)|xlam|xml|z|zip"},"user":{"uid":0,"permissionsHash":"e5117ae9e1952bc666f6f6eded612e9062e3e550f37a6e73234d0ebf81dbff34"}}</script> <script src="/sites/default/files/js/js_vMSEPHDskVi_p9TfdYxNiqFwZ_jUvnuiJNwO6MCW38g.js?scope=footer&delta=0&language=en&theme=webpac&include=eJx9jkEOwyAMBD-E4EnIxg5BdewIQ1B-314qVT3ktjs7h8WZcMayc3lxDwQDBG7uCXmHq1n3sJkOWOx2cPrJ0a8a3aTRo4EdlDxUsyqcQUHu0YqnfxAW4wklVTEE-bbNpn4-NdNM3U6ypQ9TPljnG5FMUo4"></script> </body> </html>