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Osteogenesis imperfecta (OI) | UZ Leuven
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meestal door aangeboren fouten in de collageen aanmaak, waardoor de botten vanaf de geboorte broos zijn. </div> <div class="toc hero__toc"> <div class="toc__title">Op deze pagina</div> <ul class="toc__list has-columns"> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#afspraken">Afspraken</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#symptomen">Symptomen</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#risicofactoren">Risicofactoren</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" 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<article class="l-content__cbs has-sidebar"> <div class="cbs has-sidebar"> <div class="block" id="afspraken"> <div class="block__wrapper"> <div class="block__header icon-heading"> <span class="icon-heading__icon icon "> <svg width="20" height="20" aria-hidden="true"> <use width="20" height="20" xlink:href="#calendar"></use> </svg> </span> <div class="block__title"> <h2 class="icon-heading__title heading-3">Afspraken</h2> </div></div> <div class="block__content "> <ul class="list"> <li class="list__item"> <div class="list-item"> <svg class="list-item__icon meta" width="20" height="20"> <use width="20" height="20" xlink:href="#arrow" ></use> </svg> <span class="list-item__text text" ><p><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="ecb0af6d-830a-4e97-ab57-13a4a681f1b8" data-fragment href="/nl/diensten-centra-en-afdelingen/metabole-ziekten">Metabole ziekten</a></p></span> </div> </li> <li class="list__item"> <div class="list-item"> <svg 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class="list-item__icon meta" width="20" height="20"> <use width="20" height="20" xlink:href="#mail" ></use> </svg> <span class="list-item__text text" ><p><a href="https://forms.nexuzhealth.be/forms/AfspraakAanvragen_Dienst_Kindergeneeskunde_v2?lang=nl&target=patient" target="_blank" rel="noreferrer noopener">Vraag eenvoudig uw afspraak aan</a>.</p></span> </div> </li> <li class="list__item"> <div class="list-item"> <svg class="list-item__icon meta" width="20" height="20"> <use width="20" height="20" xlink:href="#phone" ></use> </svg> <span class="list-item__text text" ><p><a href="tel:+3216343991" target="_blank" rel="noreferrer noopener">+32 16 34 39 91</a> - maandag tot donderdag van 8 tot 20 uur en vrijdag van 8 tot 17 uur</p></span> </div> </li> </ul> </div></div> </div class="block" id="afspraken-kinderen"> <div id="42aec6c2-29d3-468d-8ed6-0d8676e263b4" class="block--text text"> <h2 id="symptomen">Symptomen</h2> <p>De voornaamste kenmerken van osteogenesis imperfecta zijn:</p> <ul> <li>Blauwkleurig sclerae (oogwit).</li> <li>Hoofd is meestal groter dan normaal.</li> <li>Driehoekig gelaat waarbij bovenkaak vaak onderontwikkeld is.</li> <li>Doorschijnende tanden.</li> <li>Gehoorverlies of doofheid.</li> <li>Overmatig beweeglijke gewrichten.</li> <li>Botbreuken.</li> </ul> <h2 id="risicofactoren">Risicofactoren</h2> <ul> <li>Komt bij ongeveer 1 op 20.000 geboorten.</li> <li>Osteogenesis imperfecta is voornamelijk autosomaal dominant, m.a.w. ze gaat vaak over van ouders op kinderen.</li> <li>De meeste vormen hebben een normale levensverwachting.</li> </ul> <h2 id="behandeling">Behandeling</h2> <p>U vindt hier een aantal mogelijke behandelingen voor deze aandoening. Na de diagnose kiest uw arts, samen met u en de andere artsen van het team, de beste oplossing voor u. Uw behandeling kan dus afwijken van de hieronder voorgestelde therapie(ën).</p> <ul> <li>Behandeling hangt af van de ernst, maar orthopedische en tandheelkundige begeleiding is noodzakelijk. Een team van artsen zal een langeptermijnplan opstellen met de nodig ingrepen en juiste begeleiding.</li> <li>Calcium en vitamine D supplementen zijn onmisbaar voor alle OI patiënten.</li> <li>In sommige gevallen wordt er behandeld met botverstevigende medicatie.</li> </ul> <h2 id="onderzoeken-en-diagnose">Onderzoeken en diagnose</h2> <p>Bij (vermoeden van) deze aandoening voeren we een of meerdere onderzoeken uit.</p> </div> <div class="section section--one bg-transparent" data-content-loader=""> <div class="section__content" data-content-loader-container=""> <a class="teaser teaser--horizontal is-link" href="/nl/botmeting-botdensitometrie" target="" rel=""> <div class="teaser__content"> <h3 class="heading-3 teaser__title teaser__title--is-link"> <span>Botmeting of botdensitometrie<div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span> </h3> <div class="teaser__description">Meten van de dichtheid van het bot in de wervelzuil en de heup door middel van x-stralen, om het risico op breuken in te kunnen schatten. </div> </div> </a> <a class="teaser teaser--horizontal is-link" href="/nl/radiologie/radiografie-rx" target="" rel=""> <div class="teaser__content"> <h3 class="heading-3 teaser__title teaser__title--is-link"> <span>Radiografie (RX)<div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span> </h3> <div class="teaser__description">Röntgenstralen of RX-stralen worden door bepaalde weefsels in het lichaam tegengehouden. Stralen die door het lichaam gaan, worden gebruikt om een beeld te maken van weefsels: het röntgenbeeld. </div> </div> </a> <a class="teaser teaser--horizontal is-link" href="/nl/radiologie/mr-scan-magnetische-resonantie" target="" rel=""> <div class="teaser__content"> <h3 class="heading-3 teaser__title teaser__title--is-link"> <span>MR-scan (magnetische resonantie)<div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span> </h3> <div class="teaser__description">In het magneetveld van een MR wekken korte radiogolven signalen op in het lichaam. Een computer verwerkt de signaalintensiteiten tot allerlei doorsneden van de lichaamsregio. </div> </div> </a> <a class="teaser teaser--horizontal is-link" href="/nl/echografie" target="" rel=""> <div class="teaser__content"> <h3 class="heading-3 teaser__title teaser__title--is-link"> <span>Echografie<div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span> </h3> <div class="teaser__description">Geluidsgolven tonen een beeld van organen, spieren en andere structuren door de weerkaatsing op overgangen tussen zachte en hardere structuren. </div> </div> </a> <a class="teaser teaser--horizontal is-link" href="/nl/radiologie/ct-scan" target="" rel=""> <div class="teaser__content"> <h3 class="heading-3 teaser__title teaser__title--is-link"> <span>CT-scan<div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span> </h3> <div class="teaser__description">Beeldvormingsonderzoek waarbij met behulp van röntgenstralen gedetailleerde dwarsdoorsneden van een lichaamsdeel worden gemaakt. De computer zet die beelden om in nauwkeurige beelden van botten, organen en weefsels.</div> </div> </a> <div class="stub teaser teaser--horizontal is-link" href="" target="" rel=""> <div class="teaser__content"> <div class="teaser__heading"> <h3 class="heading-3 teaser__title"> <span>Erfelijkheidstesten</span> </h3> </div> <div class="teaser__description">Genetisch onderzoek om na te gaan of het om een erfelijke aandoening gaat.</div> </div> </div> </div> </div> <div class="section section--three" data-content-loader=""> <div class="section__heading"> <h2 class="" id="specialisten"> <span>Specialisten</span> </h2> </div> <div class="section__content" data-content-loader-container=""> <div class="card is-link" href="/nl/artsen-en-specialisten/david-cassiman" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-10/405387.jpeg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=0bc8aff6d09db6bb49ed82517f7251e0e230d072c8fe8f1aa1c39aaf6e08366b" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/david-cassiman" class="teaser__title heading-3 teaser__title--is-link"> <span>Cassiman David, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Hepatoloog</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/armand-laumen" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2021-11/armand_laumen.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=5f971f91b20539f2a6f89db10b8d5bc1de3b991b9e1fddfcb66479e63b53c107" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/armand-laumen" class="teaser__title heading-3 teaser__title--is-link"> <span>Laumen Armand, </span> <span>dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Kinderorthopedist, Orthopedisch chirurg</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/michael-laurent" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-10/509243.jpeg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=6f48c41b815b56970e88d71ae70f84e16ed1d10b37449c4afa22a495b25941cc" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/michael-laurent" class="teaser__title heading-3 teaser__title--is-link"> <span>Laurent Michaël, </span> <span>dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Geriater</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/wouter-meersseman" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-10/424213.jpeg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=a6ae4a99e3912ad2f6dc15766dd931457e85c77d5a9cd7443a63ffe8531a41fe" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/wouter-meersseman" class="teaser__title heading-3 teaser__title--is-link"> <span>Meersseman Wouter, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Intensivist, Pneumoloog</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/geert-mortier" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2022-08/geert%20mortier.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=16f13f56a9ac6bdc8d68f39f51c678e7feeec9373cba18f77990c0520072525b" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/geert-mortier" class="teaser__title heading-3 teaser__title--is-link"> <span>Mortier Geert, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Klinisch geneticus</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/daisy-rymen" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-11/daisy-rymen.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=5d41580be65dadcd98ee5c23848c93a5d758d2a3023a740c1c255603fb738d38" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/daisy-rymen" class="teaser__title heading-3 teaser__title--is-link"> <span>Rymen Daisy, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Algemene kinderarts</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/maarten-van-nuffel" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-10/507184.jpeg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=1132ff30bd49d76d47c858573bcab4ef61eaa5368c855b8e2b7e1cc05b15ae49" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/maarten-van-nuffel" class="teaser__title heading-3 teaser__title--is-link"> <span>Van Nuffel Maarten, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Orthopedisch chirurg</div> </div> </div> <div class="card is-link" href="/nl/artsen-en-specialisten/peter-witters" target="" rel=""> <img class="card__image" width="90" height="120" src="https://wmimages.uzleuven.be/styles/0967241a026ba006f8b1a5a2381dc96ba24dca27/2019-10/506237.jpeg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjE4MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOmZhbHNlfX1d&sign=9226ec69180c6b9d960404032d96b347eca510918e1c4594265cc3a46f209f5a" /> <div class="card__content"> <a href="/nl/artsen-en-specialisten/peter-witters" class="teaser__title heading-3 teaser__title--is-link"> <span>Witters Peter, </span> <span>prof. dr.<span style="margin-left: 5px"><div class="teaser__arrow"> <svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <circle cx="9" cy="9" r="8" transform="rotate(-90 9 9)" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M9 12.2L12.2 9L9 5.8" stroke="currentColor" stroke-width="1.5" stroke-linecap="square"/> <path d="M4.79999 9H11.8" stroke="currentColor" stroke-width="1.5"/> </svg> </div> </span></span> </a> <div class="card__subtitle meta">Kinderhepatoloog</div> </div> </div> </div> </div> <div id="zelfhulp-osteogenesis-imperfecta-zoi" class="media"> <div class="video__heading"> <h2 class="" id="zelfhulp-osteogenesis-imperfecta-zoi--2"> <span>Zelfhulp Osteogenesis Imperfecta (ZOI)</span> </h2> </div> <div class="media__content"> <div class="video-container"> <iframe class="wm-embed wm-embed-vimeo" width="640" height="360" src="https://player.vimeo.com/video/780704544?portrait=0&badge=0&byline=0&title=0&color=fff&autoplay=" data-src="https://player.vimeo.com/video/780704544?portrait=0&badge=0&byline=0&title=0&color=fff&autoplay=" allowfullscreen> </iframe> <span class="video-container__internal-title"> Zelfhulp Osteogenesis Imperfecta (ZOI) </span> 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Maak voor medische vragen een afspraak bij een dienst of arts."}"></div> <div class="meta"> Laatste aanpassing: 2 augustus 2023 </div> </div> </article> <aside class="l-content__sidebar"> <div class="link-list has-border"> <h2 class="heading-4">Gerelateerd</h2> <ul class="list"><li class="link-list__item"> <a href="/nl/zeldzame-ziekten">Behandeling van zeldzame ziekten in UZ Leuven</a> </li><li class="link-list__item"> <a href="https://metab.ern-net.eu/">MetabERN: European Reference Network for Hereditary Metabolic Disorders</a> </li><li class="link-list__item"> <a href="https://www.zoi.be">Zelfhulp Osteogenesis Imperfecta (ZOI)</a> </li></ul> </div> </aside> </div> </main> <footer> <div class="footer"> <div class="footer__row"> <div class="footer__inside"> <div class="footer__columns"> <div class="footer__column"> <h4 class="footer__heading heading-3">Contact</h4> <p><a href="tel:+3216332211" target="_blank" rel="noreferrer noopener">+32 16 33 22 11</a></p><p>Herestraat 49, 3000 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