CINXE.COM

<!DOCTYPE html><html lang="en"><head><link rel="stylesheet" data-href="https://fonts.googleapis.com/css?family=Trade+Gothic+Lt+Bold%7COpen+Sans%7CTrade+Gothic+Lt&display=swap" data-optimized-fonts="true"/><title>Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease</title><link rel="icon" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png"/><link rel="shortcut icon" type="image/x-icon" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png?optimizer=image&format=webp&width=180&aspectRatio=1"/><link rel="apple-touch-icon" sizes="180x180" href="https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png?optimizer=image&format=webp&width=180&aspectRatio=1"/><link rel="canonical" href="/domains/www.pharmafocus.com/articles/tiziana-life-sciences-awarded-4m-grant-by-nih-to-study-anti-cd3"/><meta name="application-name" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta name="apple-mobile-web-app-capable" content="yes"/><meta name="apple-mobile-web-app-status-bar-style" content="default"/><meta name="apple-mobile-web-app-title" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta name="format-detection" content="telephone=no"/><meta name="mobile-web-app-capable" content="yes"/><meta name="msapplication-TileColor" content="#1976D2"/><meta name="msapplication-tap-highlight" content="no"/><link rel="manifest" href="/manifest.json"/><meta name="twitter:url" content="https://www.pharmafocus.com"/><meta name="theme-color" content="#1976D2"/><meta name="viewport" content="width=device-width, initial-scale=1"/><meta charSet="utf-8"/><meta itemProp="name" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta name="keywords" content="alzheimer"/><meta itemProp="description" content="Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant."/><meta name="description" content="Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant."/><meta itemProp="image" content="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg"/><meta property="og:description" content="Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant."/><meta property="og:title" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta property="og:site_name" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta property="og:image" content="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg"/><meta property="og:type" content="website"/><meta name="twitter:card" content="summary_large_image"/><meta name="twitter:title" content="Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease"/><meta name="twitter:description" content="Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant."/><meta name="twitter:image" content="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg"/><meta name="author" content="Pharmafocus"/><meta property="article:author" content="Pharmafocus"/><meta property="article:published_time" content="2024-10-10T00:00:00.000Z"/><meta name="twitter:site" content="@Pharmafocus"/><meta name="twitter:creator" content="@Pharmafocus"/><style>html{--heading-font: "Trade Gothic Lt Bold";--body-font: "Open Sans";--ui-font: "Trade Gothic Lt Bold";--top-menu-title-font: "Trade Gothic Lt Bold";--top-menu-subtitle-font: "Trade Gothic Lt";--top-menu-items-font: "Trade Gothic Lt";--footer-menu-title-font: "Trade Gothic Lt Bold";--footer-menu-items-font: "Trade Gothic Lt Bold";--background-color: #FFFFFF;--background-color-dark: #808080;--primary-color: #1976D2;--primary-color-dark: #0C3B69;--secondary-color: #795FF4;--secondary-color-dark: #250B9F;--accent-color: #D76FD6;--accent-color-dark: #80237F;--info-color: #41638C;--info-color-dark: #213246;--warning-color: #EF9338;--warning-color-dark: #89490B;--success-color: #20AD27;--success-color-dark: #105714;--danger-color: #DF4241;--danger-color-dark: #7B1515;--top-menu-background-color: #EE1C25;--top-menu-background-color-dark: #7C090E;--footer-menu-background-color: #DF1111;--footer-menu-background-color-dark: #6F0808;--navbar-height: 64px; }</style><link rel="stylesheet" href="https://cdn.magloft.com/reader/fonts/trade-gothic-lt.css"/><link rel="stylesheet" href="https://cdn.magloft.com/reader/fonts/trade-gothic-lt-bold.css"/><script type="text/javascript" src="https://cdn.jsdelivr.net/npm/cookie-bar/cookiebar-latest.min.js?customize=1&always=1&showNoConsent=1"></script><meta name="google-site-verification" content="kuOvGxaH_NjG3aS7GSmbjjV-OjdOAWyiM3gEPGESeHQ"/><style> #billboard-banner { text-align:center;} #billboard-banner img {width:100%; max-width:970px; height:auto; position:relative; top:70px;} .Layout_spacer__qTBD3 {margin-top:70px;} </style><meta name="next-head-count" content="44"/><link rel="preconnect" href="https://fonts.googleapis.com"/><link rel="preconnect" href="https://fonts.gstatic.com"/><link rel="preload" href="/_next/static/css/229efe2956472d85.css" as="style"/><link rel="stylesheet" href="/_next/static/css/229efe2956472d85.css" data-n-g=""/><link rel="preload" href="/_next/static/css/7c74bf24f71f6c9d.css" as="style"/><link rel="stylesheet" href="/_next/static/css/7c74bf24f71f6c9d.css" data-n-p=""/><link rel="preload" href="/_next/static/css/eaa0062c2481f7ca.css" as="style"/><link rel="stylesheet" href="/_next/static/css/eaa0062c2481f7ca.css" data-n-p=""/><noscript data-n-css=""></noscript><script defer="" nomodule="" src="/_next/static/chunks/polyfills-c67a75d1b6f99dc8.js"></script><script defer="" src="https://fonts.googleapis.com/css?family=Open+Sans&display=swap" data-nscript="beforeInteractive"></script><script src="/_next/static/chunks/webpack-b653c683a51d8b57.js" defer=""></script><script src="/_next/static/chunks/framework-73b8966a3c579ab0.js" defer=""></script><script src="/_next/static/chunks/main-34cb81d5753e1fc4.js" defer=""></script><script src="/_next/static/chunks/pages/_app-6805a2020fbcfa43.js" defer=""></script><script src="/_next/static/chunks/ad273671-3092333ffa02af02.js" defer=""></script><script src="/_next/static/chunks/876-c944523f292a2885.js" defer=""></script><script src="/_next/static/chunks/223-fe6833f316a5a95f.js" defer=""></script><script src="/_next/static/chunks/174-d95909d2aa5e8ec8.js" defer=""></script><script src="/_next/static/chunks/302-d0f1826200f9f2a4.js" defer=""></script><script src="/_next/static/chunks/pages/domains/%5Bdomain%5D/articles/%5Bslug%5D-12d0888066c7f18b.js" defer=""></script><script src="/_next/static/U1LT7ce93wR6IyWFJCllT/_buildManifest.js" defer=""></script><script src="/_next/static/U1LT7ce93wR6IyWFJCllT/_ssgManifest.js" defer=""></script><style data-styled="" data-styled-version="5.3.9"></style><link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Trade+Gothic+Lt+Bold%7COpen+Sans%7CTrade+Gothic+Lt&display=swap"/></head><body><div id="__next"><div class="Layout_container__gktH6"><div class="Layout_navbar-container__gCfDZ" style="height:64px"><nav class="_wrapper_jbnbd_1"><div class="_container_jbnbd_15"><div class="_navbar-prefix_jbnbd_108"><div class="Layout_prefix__7W2Vq"><button><div class="_nav-arrow-left_1lm7t_183 _icon_1lm7t_1 icon"></div></button></div></div><a class="_navbar-brand_jbnbd_29" aria-label="Pharmafocus" href="/"><div class="_navbar-image_jbnbd_40"><img alt="Logo" loading="lazy" decoding="async" data-nimg="fill" class="_image_jbnbd_43" style="position:absolute;height:100%;width:100%;left:0;top:0;right:0;bottom:0;color:transparent" sizes="100vw" srcSet="https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 54w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 70w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 82w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 96w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 110w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 128w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 138w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 192w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 200w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 252w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 260w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 298w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 378w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 384w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 520w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 640w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 756w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 828w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1080w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1200w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 1920w, https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png 2048w" src="https://media.magloft.app/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png"/></div><div class="_navbar-title_jbnbd_58 _navbar-title-hide_jbnbd_101"></div></a><div id="navbar-children-container" class="_navbar-children_jbnbd_116"><div class="_menu_1jhrl_1"><div class="_menu-wrapper_1jhrl_22"><div class="_menu-items_1jhrl_38"><a class="_menu-item_1jhrl_38" href="/"><div class="_menu-home_1lm7t_255 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Home</div><div class="_indicator_1jhrl_63"></div></a><a class="_menu-item_1jhrl_38 _active_1jhrl_70" href="/articles"><div class="_menu-articles_1lm7t_259 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Articles</div><div class="_indicator_1jhrl_63 _active_1jhrl_70"></div></a><a class="_menu-item_1jhrl_38" href="/collections"><div class="_menu-issues_1lm7t_263 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Magazines</div><div class="_indicator_1jhrl_63"></div></a><a class="_menu-item_1jhrl_38" href="/account/login"><div class="_menu-account_1lm7t_411 _menu-item-icon_1jhrl_97 _icon_1lm7t_1 icon"></div><div class="_menu-item-title_1jhrl_88">Log in</div><div class="_indicator_1jhrl_63"></div></a></div></div></div></div><div id="navbar-suffix" class="_navbar-suffix_jbnbd_108"><div class="Layout_menu-actions__vsDbI"><div class="Layout_install-button__FBfSr"><div class="Tooltip_tooltip__98Sw9"></div><button class="_button_19h3g_1 _text_19h3g_12 _medium_19h3g_38 _secondary_19h3g_22" type="button" style="color:var(--top-menu-item-icon-color, var(--background-color))" role="button" aria-label="Search" aria-labelledby="labeldiv" title="Search"><div class="_action-search_1lm7t_15 _icon-button_19h3g_19 _icon_1lm7t_1 icon" style="background-color:var(--top-menu-item-icon-color, var(--background-color))"></div></button></div></div></div></div></nav></div><div class="Layout_main__evUHx"><div class="Layout_spacer__qTBD3" style="height:64px"></div><div class=""><div class=""></div><div class=""><div id="print-article" class="_slug__article__BPEHu"><div class="Article-module_article__kO4b9"><div id="outer" data-widget="page-widget" style="background-color:#FFFFFF;padding:16px 0px 24px 0px;color:#000000;text-align:left;font-family:"Open Sans"" class="Widget-module_outer__PBh8P Page-module_outer__g0XXH"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 0px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Clinical Trials</p></div></div><div id="outer" data-widget="horizontal-rule-widget" style="background-color:transparent;padding:0px 24px 0px 24px" class="Widget-module_outer__PBh8P HorizontalRule-module_outer__3UqSE"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><hr style="border-top-style:solid;border-top-width:3px;border-top-color:#a31f29"/></div></div><div id="outer" data-widget="heading-widget" style="background-color:transparent;padding:0px 24px 16px 24px;text-align:left;font-size:90%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Heading-module_container__uHf-4"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%"><h2><span style="font-family:"Roboto Slab"" class="__bold">Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease</span></h2></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p><span class="__bold" style="color:rgb(28,28,28)">Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH), National Institute on Aging have awarded a $4m grant to Dr Howard Weiner as principal investigator at Brigham and Women’s Hospital to be the key research site to study nasal anti-CD3 for the treatment of Alzheimer’s disease (AD). </span></p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>The NIH grant will allow ongoing research efforts to continue, including preclinical studies and preparations for clinical trials, for nasal anti-CD3. The research will look at its ability to modulate immune system activity, reduce neuroinflammation and ultimately slow the progression of AD. Anti-CD3 is administered intranasally, binding to the T-cell receptor and stimulating T regulatory cells for delivery to the central nervous system.</p></div></div><div id="outer" data-widget="image-widget" style="background-color:transparent;padding:8px 24px 16px 24px;min-height:auto" class="Widget-module_outer__PBh8P"><div id="inner" class="Image-module_container__8raIv Image-module_container-noflex__-J1PG" style="border-radius:0px 0px 0px 0px;width:100%;min-height:auto"><picture class="Image-module_picture__gw1zY Image-module_loading__FfyPr"><source type="image/jpeg" srcSet="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=192 192w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=384 384w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=768 768w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=1536 1536w" sizes="(min-width: 768px) 768px, 100vw"/><img src="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=768" srcSet="https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=192 192w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=384 384w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=768 768w,https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg?optimizer=image&width=1536 1536w" sizes="(min-width: 768px) 768px, 100vw" class="Image-module_image__w4slc" width="100%" height="961" decoding="async" alt="Image" style="height:auto;width:100%"/></picture></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Howard L Weiner MD, principal investigator, chairman of Tiziana’s Scientific Advisory Board and codirector of the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital, stated: “AD is the most common form of dementia, affecting more than six million people in the US alone. Despite extensive research, effective treatments remain limited, and the need for innovative therapeutic approaches is urgent.”</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Ivor Elrifi, CEO of Tiziana Life Sciences, commented, “We are thrilled to be able to progress our pipeline with this prestigious NIH grant, which underscores the potential of our antiCD3 therapy to address a critical unmet need in AD. This funding will enable us to expand our research and move one step closer to developing a new therapeutic option for patients and families impacted by this debilitating condition. At Tiziana, we remain committed to advancing science that could improve the quality of life for patients through groundbreaking immunotherapies.”</p></div></div><div id="outer" data-widget="paragraph-widget" style="background-color:transparent;padding:0px 24px 8px 24px;text-align:left;font-size:100%;line-height:1.3;letter-spacing:0" class="Widget-module_outer__PBh8P Paragraph-module_container__-DJUN"><div id="inner" style="border-radius:0px 0px 0px 0px;width:100%;column-count:1"><p>Alzheimer's disease is a progressive condition, which means the symptoms develop gradually over many years and eventually become more severe. Alzheimer's disease is the most common cause of dementia in the UK.</p></div></div></div></div></div><div class="_slug__share-button__ettip"><hr/></div></div></div><div id="ControlBar" class="_slug__control-bar__Jj4LE"><div class="WrapAutoHide-module_navigation__9sdQy WrapAutoHide-module_visible__UN7GD"><div class="ControlBar-module_toc-wrapper__AF5eD"><div class="ControlBar-module_toc__mKXnp"><div class="ControlBar-module_white-blur__TGapK"><div class="ControlBar-module_toc-slider__i9fv1"></div></div><div class="ControlBar-module_control-bar__9Zqak"><button class=""><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none"><path d="M13.8287 19C13.5367 19 13.2467 18.873 13.0487 18.627L8.22066 12.627C7.92266 12.256 7.92666 11.726 8.23166 11.36L13.2317 5.35998C13.5847 4.93598 14.2157 4.87898 14.6407 5.23198C15.0647 5.58498 15.1217 6.21598 14.7677 6.63998L10.2927 12.011L14.6077 17.373C14.9537 17.803 14.8857 18.433 14.4547 18.779C14.2707 18.928 14.0487 19 13.8287 19Z" fill="white"></path></svg></button><button class=""><svg xmlns="http://www.w3.org/2000/svg" width="18" height="14" viewBox="0 0 18 14" fill="none"><path d="M6.75 0H1.125C0.503719 0 0 0.503719 0 1.125V4.5C0 5.12128 0.503719 5.625 1.125 5.625C1.74628 5.625 2.25 5.12128 2.25 4.5V2.25H6.75C7.37128 2.25 7.875 1.74628 7.875 1.125C7.875 0.503719 7.37128 0 6.75 0Z" fill="white"></path><path d="M16.875 0H11.25C10.6287 0 10.125 0.503719 10.125 1.125C10.125 1.74628 10.6287 2.25 11.25 2.25H15.75V4.5C15.75 5.12128 16.2537 5.625 16.875 5.625C17.4963 5.625 18 5.12128 18 4.5V1.125C18 0.503719 17.4963 0 16.875 0Z" fill="white"></path><path d="M16.875 7.875C16.2537 7.875 15.75 8.37872 15.75 9V11.25H11.25C10.6287 11.25 10.125 11.7537 10.125 12.375C10.125 12.9963 10.6287 13.5 11.25 13.5H16.875C17.4963 13.5 18 12.9963 18 12.375V9C18 8.37872 17.4963 7.875 16.875 7.875Z" fill="white"></path><path d="M6.75 11.25H2.25V9C2.25 8.37872 1.74628 7.875 1.125 7.875C0.503719 7.875 0 8.37872 0 9V12.375C0 12.9963 0.503719 13.5 1.125 13.5H6.75C7.37128 13.5 7.875 12.9963 7.875 12.375C7.875 11.7537 7.37128 11.25 6.75 11.25Z" fill="white"></path></svg></button><button class="" disabled=""><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none"><g opacity="0.25"><path d="M9.9995 19C9.7735 19 9.5465 18.924 9.3595 18.768C8.9355 18.415 8.8785 17.784 9.2315 17.36L13.7075 11.989L9.3925 6.62701C9.0465 6.19701 9.1145 5.56701 9.5445 5.22101C9.9755 4.87501 10.6045 4.94301 10.9515 5.37301L15.7795 11.373C16.0775 11.744 16.0735 12.274 15.7685 12.64L10.7685 18.64C10.5705 18.877 10.2865 19 9.9995 19Z" fill="white"></path></g></svg></button></div></div></div></div></div><div class="_slug__wrapper__0ZIJf"></div><div></div></div></div><script> //create a new element const terms = document.createElement('div'); //set id terms.setAttribute("id","billboard-banner"); //add the new element to html var body = document.querySelector('body'); body.appendChild(terms); document.querySelector("#billboard-banner").innerHTML = "<ins data-revive-zoneid='1573' data-revive-id='9c421b7e485bf2edfee09708a4d06e2e'></ins>"; //insert new element before header //document.body.insertAdjacentElement('afterbegin', terms); const insElement = document.querySelector("#__next"); insElement.before(terms); </script> <script async="" src="//ads.datateam.co.uk/www/delivery/asyncjs.php"></script><div class="_footer_j8nu5_1"><div class="_container_j8nu5_12"><div class="_footer-row_j8nu5_23"><div class="_footer-column_j8nu5_36 _flex-2_j8nu5_117"><div class="_footer-brand_j8nu5_43"><div class=""><img alt="Logo" loading="lazy" width="40" height="40" decoding="async" data-nimg="1" class="_footer-logo_j8nu5_57" style="color:transparent" srcSet="https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png 1x, https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png 2x" src="https://media.magloft.app/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png"/></div><div class="_content_j8nu5_67"><h3>Pharmafocus</h3><p>Pharmaceutical Industry news, analysis and insights</p></div></div><div class="_footer-link-list_j8nu5_121"><div class="_block_j8nu5_129"><a class="_footer-link-item_j8nu5_92" rel="noreferrer" href="mailto:info@pharmafile.com"><div class="_form-email_1lm7t_143 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>info@pharmafile.com</span></a></div><div class="_block_j8nu5_129"><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="http://www.pharmafile.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Pharmafile.com</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://magazine.pharmafile.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Pharmafile Magazine</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="http://www.samedanltd.com"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Samedan</span></a></div><a target="_blank" rel="noreferrer" class="_footer-link-item_j8nu5_92" href="https://www.pharmafile.com/privacy-policy"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Privacy Policy</span></a><a target="_blank" rel="noreferrer" class="_footer-link-item_j8nu5_92" href="https://www.pharmafile.com/terms-of-service"><div class="_status-info_1lm7t_87 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span>Terms of Service</span></a></div></div><div class="_footer-column_j8nu5_36 _flex-1_j8nu5_39"><div class="_footer-brand_j8nu5_43"><div class="_status-accent_1lm7t_91 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><div class="_content_j8nu5_67"><h3>Categories</h3><p>Explore our inspiring content by topic</p></div></div><div class="_footer-link-list_j8nu5_121"><a class="_footer-link-item_j8nu5_92" href="/categories/uk-pharma-news"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>UK News</a><a class="_footer-link-item_j8nu5_92" href="/categories/general-news"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>General News</a><a class="_footer-link-item_j8nu5_92" href="/categories/approvals"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Approvals</a><a class="_footer-link-item_j8nu5_92" href="/categories/research-and-development"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>R & D</a><a class="_footer-link-item_j8nu5_92" href="/categories/mergers-acquisitions"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Mergers & Acquisitions</a><a class="_footer-link-item_j8nu5_92" href="/categories/manufacturing-production"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Manufacturing</a><a class="_footer-link-item_j8nu5_92" href="/categories/clinical-trials"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Clinical Trials</a><a class="_footer-link-item_j8nu5_92" href="/categories/industry-insights"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Industry Insights</a><a class="_footer-link-item_j8nu5_92" href="/categories/appointments"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Appointments</a><a class="_footer-link-item_j8nu5_92" href="/categories/insider-interviews"><div class="_nav-arrow-right_1lm7t_175 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div>Interviews</a></div></div><div class="_footer-column_j8nu5_36 _flex-1_j8nu5_39"><div class="_footer-brand_j8nu5_43"><div class="_share-action_1lm7t_463 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><div class="_content_j8nu5_67"><h3>Social Footprints</h3><p>Follow us on our Social Media Channels</p></div></div><div class="_footer-link-list_j8nu5_121"><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://twitter.com/Pharmafocus"><div class="_share-twitter_1lm7t_487 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span class="_footer-text_j8nu5_125">X</span></a><a class="_footer-link-item_j8nu5_92" target="_blank" rel="noreferrer" href="https://www.linkedin.com/company/pharmafile"><div class="_share-linkedin_1lm7t_483 _footer-icon_j8nu5_58 _icon_1lm7t_1 icon"></div><span class="_footer-text_j8nu5_125">linkedin</span></a></div></div></div></div></div></div><div class="Toastify"></div></div><script id="__NEXT_DATA__" type="application/json">{"props":{"pageProps":{"domain":"www.pharmafocus.com","pwa":{"id":664,"publicationId":14882,"pwaOptinId":656,"domain":"www.pharmafocus.com","config":{"access":{"concurrentLimit":null,"restrictAnonymous":null,"disableSignup":null,"disableLogin":null,"disableLoginMessage":null,"disableSearchIndexing":false,"signupUrl":null,"resetPasswordUrl":null,"isUsernameLogin":null,"disableEditProfile":null,"formUrl":null,"customMarginResetPassword":null},"push":{"google":{"serverPublicKey":"BGfKWie38SRvrZs4-bDa1N70rhULMBqX8nAvBZT_2OXsMQi3uRA0CaK4JKPuib9Ega28liCTGhBx0QCY4t1QU7o"}},"tracking":{"facebook":{"appId":null,"pixelId":null},"google":{"measurementId":"G-D8QLP3CKWG"},"gtm":null,"sentry":true},"payment":{"stripe":null,"bypassPayment":null,"mode":"none","external":null,"currency":null},"email":{"readerOptin":false},"firebase":{"projectId":"ipt-magloft","senderId":"497261264876","pairKey":null,"webAppConfig":{"apiKey":"AIzaSyBcHBC8k394YdXp19dZj2Xqe8CXCgThBZs","appId":"1:497261264876:web:98452398b320341bd68ac9","authDomain":"ipt-magloft.firebaseapp.com","databaseURL":null,"locationId":null,"messagingSenderId":"497261264876","projectId":"ipt-magloft","storageBucket":"ipt-magloft.appspot.com"}},"customHtml":{"head":"\u003cscript type=\"text/javascript\" src=\"https://cdn.jsdelivr.net/npm/cookie-bar/cookiebar-latest.min.js?customize=1\u0026always=1\u0026showNoConsent=1\" onload=\"setupCookieBar();\"\u003e\u003c/script\u003e\n\u003cmeta name=\"google-site-verification\" content=\"kuOvGxaH_NjG3aS7GSmbjjV-OjdOAWyiM3gEPGESeHQ\" /\u003e\n\u003cstyle\u003e\n#billboard-banner { text-align:center;}\n#billboard-banner img {width:100%; max-width:970px; height:auto; position:relative; top:70px;}\n.Layout_spacer__qTBD3 {margin-top:70px;}\n\u003c/style\u003e","body":"\u003cscript\u003e\n //create a new element\n const terms = document.createElement('div');\n //set id\n terms.setAttribute(\"id\",\"billboard-banner\");\n //add the new element to html\n var body = document.querySelector('body');\n body.appendChild(terms);\n document.querySelector(\"#billboard-banner\").innerHTML = \"\u003cins data-revive-zoneid='1573' data-revive-id='9c421b7e485bf2edfee09708a4d06e2e'\u003e\u003c/ins\u003e\"; \n //insert new element before header\n//document.body.insertAdjacentElement('afterbegin', terms);\n const insElement = document.querySelector(\"#__next\");\n insElement.before(terms);\n\u003c/script\u003e\n\u003cscript async src=\"//ads.datateam.co.uk/www/delivery/asyncjs.php\"\u003e\u003c/script\u003e"},"account":{"emailEditable":true,"customSubscriptionText":null,"customSubscriptionURL":null,"enableSubscriptionTitle":null},"checkout":null},"design":{"colors":{"backgroundColor":"#FFFFFF","primaryColor":"#1976D2","secondaryColor":"#795FF4","accentColor":"#D76FD6","infoColor":"#41638C","warningColor":"#EF9338","successColor":"#20AD27","dangerColor":"#DF4241","topMenuBackgroundColor":"#EE1C25","topMenuHeadingTitleColor":null,"topMenuHeadingIconColor":null,"topMenuItemTextColor":null,"topMenuItemIconColor":null,"footerMenuBackgroundColor":"#DF1111","footerMenuHeadingTitleColor":null,"footerMenuHeadingTextColor":null,"footerMenuHeadingIconColor":null,"footerMenuItemTextColor":null,"footerMenuItemIconColor":null},"images":{"icon":"https://cdn.magloft.com/pwa-664/pwa/logo/8eb186e1-b2cb-4384-a0b7-515f62171b22.png","feature":"https://cdn.magloft.com/defaults/feature-graphic.jpg","topMenuIcon":"https://cdn.magloft.com/pwa-664/pwa/top-menu-icon/c215ba48-44be-411d-8753-7438a6acf8fb.png","footerMenuIcon":null,"alphaChannelIcon":null},"fonts":{"heading":"trade-gothic-lt-bold","body":"open-sans","ui":"trade-gothic-lt-bold","topMenuTitle":"trade-gothic-lt-bold","topMenuItems":"trade-gothic-lt","topMenuSubtitle":"trade-gothic-lt","footerMenuTitle":null,"footerMenuItems":null},"menuItems":{"collections":{"title":"Magazines"},"articles":{"title":null},"account":{"title":null},"icons":{"enabled":true}},"footerShape":"flat","issueCoverAspectRatio":0.75,"fullscreenCollectionView":"auto","customOverlayToggleView":false,"defaultViewMode":"html","categories":"flat","purchaseList":true,"libraryList":false,"noteList":false,"textToSpeech":false},"layout":{"banners":[{"image":"https://cdn.magloft.com/pwa-1/pwa/banner/aea74608-e04a-4649-b817-c45cc439e28e.png","title":"Start trial now","isHidden":true,"action":{"type":"url","href":"https://www.magloft.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}],"bottomBanners":[{"image":"https://cdn.magloft.com/pwa-664/pwa/banner/1f66e6ea-9b3a-4477-aba1-18abf54619b8.png","title":null,"isHidden":true,"action":{"type":"url","href":"http://www.samedanltd.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}],"columnSeparator":"shadow","tabs":[{"route":"","title":"Home","icon":"menu-home","visible":true},{"route":"/articles","title":"Articles","icon":"menu-articles","visible":true},{"route":"/collections","title":"Collections","icon":"menu-issues","visible":true},{"route":"/account","title":"Account","icon":"menu-account","visible":true}],"topMenu":{"showLogo":true,"showSubtitle":false,"showTitle":false,"height":"64px"},"navbar":{"animation":false,"style":"logo-left"},"sections":[{"fullWidth":true,"backgroundColor":"transparent","columnSeparator":"none","columns":[{"size":5,"blocks":[{"type":"banner","image":"https://cdn.magloft.com/pwa-1/pwa/banner/aea74608-e04a-4649-b817-c45cc439e28e.png","isHidden":true,"title":"Start trial now","action":{"type":"url","href":"https://www.magloft.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}]}]},{"fullWidth":false,"backgroundColor":null,"columnSeparator":"shadow","columns":[{"size":8.5,"blocks":[{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":892,"condition":null},{"type":"article-list","condition":null,"color":"#F90505","title":"Top Content","variant":"variant-b","articleIds":[262748,254614,260494,260493,260492,258749],"articles":null},{"type":"article-list","condition":null,"color":"#2873B0","title":"Industry Insights","variant":"variant-b","articleIds":[260492,260493,260494,258746,258745,257361],"articles":null},{"type":"article-category","condition":null,"color":"#F90505","title":"UK News","variant":"variant-c","categoryId":43138,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"Global News","variant":"variant-c","categoryId":43140,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[1319],"adCampaignId":null,"condition":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"European News","variant":"variant-c","categoryId":43139,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"guide-install","color":"#444558","title":"How to Install","condition":null}]},{"size":3.5,"blocks":[{"type":"issue-slider","condition":null,"color":"#2873B0","title":"Latest Editions","issueIds":[52826,52799,52483,52217,51921,51722,51533,51435,51240,51075,45938,45939,45940],"thumbnail":{"style":"full-cover","size":"medium"},"borderRadius":null,"zoomOnHover":true,"issues":null},{"type":"ad","title":"Advertisement","advertisementIds":[2210],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-gift","color":"#FB0505","title":"Newsletters","description":"Sign up to our newsletters and digital magazines","action":{"type":"url","href":"https://curwoodcmsltd.formstack.com/forms/samedan","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[2067],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-day","color":"#F90505","title":"Pharmafocus Archive","description":"Browse older editions","action":{"type":"url","href":"https://en.calameo.com/subscriptions/6188508","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":1044,"condition":null},{"type":"article-category","condition":null,"color":"#F70707","title":"Appointments","variant":"variant-c","categoryId":43146,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[2249,1320],"adCampaignId":null,"condition":null}]}]},{"fullWidth":true,"backgroundColor":"transparent","columnSeparator":"none","columns":[{"size":5,"blocks":[{"type":"banner","image":"https://cdn.magloft.com/pwa-664/pwa/banner/1f66e6ea-9b3a-4477-aba1-18abf54619b8.png","isHidden":true,"title":"","action":{"type":"url","href":"http://www.samedanltd.com/","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}}]}]}],"columns":[{"size":8.5,"blocks":[{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":892,"condition":null},{"type":"article-list","condition":null,"color":"#F90505","title":"Top Content","variant":"variant-b","articleIds":[262748,254614,260494,260493,260492,258749],"articles":null},{"type":"article-list","condition":null,"color":"#2873B0","title":"Industry Insights","variant":"variant-b","articleIds":[260492,260493,260494,258746,258745,257361],"articles":null},{"type":"article-category","condition":null,"color":"#F90505","title":"UK News","variant":"variant-c","categoryId":43138,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"Global News","variant":"variant-c","categoryId":43140,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[1319],"adCampaignId":null,"condition":null},{"type":"article-category","condition":null,"color":"#2873B0","title":"European News","variant":"variant-c","categoryId":43139,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"guide-install","color":"#444558","title":"How to Install","condition":null}]},{"size":3.5,"blocks":[{"type":"issue-slider","condition":null,"color":"#2873B0","title":"Latest Editions","issueIds":[52826,52799,52483,52217,51921,51722,51533,51435,51240,51075,45938,45939,45940],"thumbnail":{"style":"full-cover","size":"medium"},"borderRadius":null,"zoomOnHover":true,"issues":null},{"type":"ad","title":"Advertisement","advertisementIds":[2210],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-gift","color":"#FB0505","title":"Newsletters","description":"Sign up to our newsletters and digital magazines","action":{"type":"url","href":"https://curwoodcmsltd.formstack.com/forms/samedan","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[2067],"adCampaignId":null,"condition":null},{"type":"cta","condition":null,"icon":"symbol-day","color":"#F90505","title":"Pharmafocus Archive","description":"Browse older editions","action":{"type":"url","href":"https://en.calameo.com/subscriptions/6188508","target":"_blank","pwaSubscriptionId":null,"pwaSubscription":null,"optinId":null,"optin":null}},{"type":"ad","title":"Advertisement","advertisementIds":[],"adCampaignId":1044,"condition":null},{"type":"article-category","condition":null,"color":"#F70707","title":"Appointments","variant":"variant-c","categoryId":43146,"backgroundColor":null,"image":null,"articles":null,"category":null},{"type":"ad","title":"Advertisement","advertisementIds":[2249,1320],"adCampaignId":null,"condition":null}]}]},"seo":{"home":{"title":"Pharmafocus Magazine - covering pharma and biotech since 1986","description":"Reporting on the pharma industry, drug development \u0026 clinical trials, manufacturing, logistics, market access, and patients.\nFrom breaking stories to interviews with senior executives, we look at regulations \u0026 trends to provide useful market intelligence.","image":"https://cdn.magloft.com/pwa-664/seo/image/270800d8-b1de-41b8-86ad-5d262d2b9adf.png","imageAlt":"Pharmafocus Magazine"},"articles":{"title":"Pharmafocus - Articles","description":"Discover the latest articles published by Pharmafocus. Browse and customize the article feed to your preferences and explore latest trends","image":"https://cdn.magloft.com/pwa-664/seo/image/e7a95017-d617-4914-b4b3-09fcfc683f75.png","imageAlt":"Pharmafocus - Articles"},"issues":{"title":"Pharmafocus - Magazine Issues","description":"Explore the latest issues of Pharmafocus Magazine and keep up to date with the latest industry knowledge","image":"https://cdn.magloft.com/pwa-664/seo/image/b1c374f3-b368-4654-bf00-3b5ed81fe6c2.png","imageAlt":"Pharmafocus - Issues"},"account":{"title":"Pharmafocus - Account","description":"Manage your Pharmafocus Reader Account..","image":"https://cdn.magloft.com/pwa-664/seo/image/5ad881b1-a927-4fb1-b331-81963e9a0f84.png","imageAlt":"Reader Account"}},"strings":{"app":{"title":"Pharmafocus","subtitle":"Pharmaceutical Industry news, analysis and insights"},"social":{"facebook":null,"twitter":"https://twitter.com/Pharmafocus","linkedin":"https://www.linkedin.com/company/pharmafile","youtube":null,"instagram":null},"topMenu":{"title":null,"subtitle":null},"footerMenu":{"title":"Pharmafocus","subtitle":null,"description":null,"email":["info@pharmafile.com"],"privacyUrl":"https://www.pharmafile.com/privacy-policy","termsUrl":"https://www.pharmafile.com/terms-of-service","links":[{"name":"Pharmafile.com","url":"http://www.pharmafile.com"},{"name":"Pharmafile Magazine","url":"https://magazine.pharmafile.com"},{"name":"Samedan","url":"http://www.samedanltd.com"}]},"pages":null},"customFonts":[{"identifier":"trade-gothic-lt"},{"identifier":"trade-gothic-lt-bold"}],"phrases":{},"trialEndAt":null,"bypassSubscription":false},"publication":{"id":14882,"title":"Pharmafocus","properties":{"subtitle":null,"appIcon":"images/defaults/app-icon.png","promotionalText":null,"companyName":null,"emailReplyTo":"","privacyUrl":null,"termsUrl":null}},"categories":[{"id":43138,"slug":"uk-pharma-news","title":"UK News","color":"#444444","issueCount":3,"articleCount":79,"categoryGroupIds":[]},{"id":43139,"slug":"general-news","title":"General News","color":"#444444","issueCount":3,"articleCount":78,"categoryGroupIds":[]},{"id":43140,"slug":"approvals","title":"Approvals","color":"#444444","issueCount":3,"articleCount":159,"categoryGroupIds":[]},{"id":43141,"slug":"research-and-development","title":"R \u0026 D","color":"#444444","issueCount":1,"articleCount":174,"categoryGroupIds":[]},{"id":43143,"slug":"mergers-acquisitions","title":"Mergers \u0026 Acquisitions","color":"#444444","issueCount":0,"articleCount":69,"categoryGroupIds":[]},{"id":43144,"slug":"manufacturing-production","title":"Manufacturing","color":"#444444","issueCount":1,"articleCount":31,"categoryGroupIds":[]},{"id":43149,"slug":"clinical-trials","title":"Clinical Trials","color":"#444444","issueCount":2,"articleCount":33,"categoryGroupIds":[]},{"id":43145,"slug":"industry-insights","title":"Industry Insights","color":"#444444","issueCount":1,"articleCount":56,"categoryGroupIds":[]},{"id":43146,"slug":"appointments","title":"Appointments","color":"#444444","issueCount":2,"articleCount":87,"categoryGroupIds":[]},{"id":43147,"slug":"insider-interviews","title":"Interviews","color":"#444444","issueCount":0,"articleCount":9,"categoryGroupIds":[]},{"id":43148,"slug":"features","title":"Features","color":"#444444","issueCount":0,"articleCount":20,"categoryGroupIds":[]},{"id":43142,"slug":"industry-facts","title":"Industry Facts","color":"#444444","issueCount":2,"articleCount":23,"categoryGroupIds":[]}],"pwaSubscriptions":[],"categoryGroups":[],"slug":"tiziana-life-sciences-awarded-4m-grant-by-nih-to-study-anti-cd3","article":{"id":266512,"slug":"tiziana-life-sciences-awarded-4m-grant-by-nih-to-study-anti-cd3","issueId":52483,"categoryIds":[43141,43140],"title":"Tiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease","description":"Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant to Dr Howard Weiner as principal investigator at Brigham and Women’s Hospital to be the key research site to study nasal anti-cd3 for the treatment of alzheimer’s disease (ad).","image":"https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg","cover":"https://cdn.magloft.com/publication-14882/screenshots/articles/266512.jpg?ts=1728470644","date":1728601200000,"unlockType":"free","categories":[],"pdfPageId":"QRk6tn4GJotw","visible":true,"showOnToc":true,"bookmark":false,"position":14,"publicationId":14882,"pwaOptinId":null,"seoDescription":"Tiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH),'s National Institute on Aging has awarded a $4m grant.","classificationIds":[],"pwaSubscriptionIds":[],"source":"typeloft2","trending":false,"html":"\u003cpage-widget padding=\"16 0 24 0\"\u003e\u003cparagraph-widget padding=\"0 24 0 24\"\u003eClinical Trials\u003c/paragraph-widget\u003e\u003chorizontal-rule-widget padding=\"0 24 0 24\" color=\"#a31f29\"\u003e\u003c/horizontal-rule-widget\u003e\u003cheading-widget padding=\"0 24 16 24\" font-size=\"90\" type=\"h2\"\u003e\u003cspan style=\"font-family: \u0026quot;Roboto Slab\u0026quot;;\" class=\"__bold\"\u003eTiziana Life Sciences awarded $4m grant by NIH to study anti-CD3 in Alzheimer’s disease\u003c/span\u003e\u003c/heading-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003e\u003cspan class=\"__bold\" style=\"color: rgb(28,28,28)\"\u003eTiziana Life Sciences, a biotechnology company developing immunomodulation therapies, announced that the National Institutes of Health (NIH), National Institute on Aging have awarded a $4m grant to Dr Howard Weiner as principal investigator at Brigham and Women’s Hospital to be the key research site to study nasal anti-CD3 for the treatment of Alzheimer’s disease (AD). \u003c/span\u003e\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eThe NIH grant will allow ongoing research efforts to continue, including preclinical studies and preparations for clinical trials, for nasal anti-CD3. The research will look at its ability to modulate immune system activity, reduce neuroinflammation and ultimately slow the progression of AD. Anti-CD3 is administered intranasally, binding to the T-cell receptor and stimulating T regulatory cells for delivery to the central nervous system.\u003c/paragraph-widget\u003e\u003cimage-widget padding=\"8 24 16 24\" aspect-ratio=\"1.2506738544474394\" magnify-label=\"center\" source=\"https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg#image/jpeg\"\u003e\u003c/image-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eHoward L Weiner MD, principal investigator, chairman of Tiziana’s Scientific Advisory Board and codirector of the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital, stated: “AD is the most common form of dementia, affecting more than six million people in the US alone. Despite extensive research, effective treatments remain limited, and the need for innovative therapeutic approaches is urgent.”\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eIvor Elrifi, CEO of Tiziana Life Sciences, commented, “We are thrilled to be able to progress our pipeline with this prestigious NIH grant, which underscores the potential of our antiCD3 therapy to address a critical unmet need in AD. This funding will enable us to expand our research and move one step closer to developing a new therapeutic option for patients and families impacted by this debilitating condition. At Tiziana, we remain committed to advancing science that could improve the quality of life for patients through groundbreaking immunotherapies.”\u003c/paragraph-widget\u003e\u003cparagraph-widget padding=\"0 24 8 24\"\u003eAlzheimer's disease is a progressive condition, which means the symptoms develop gradually over many years and eventually become more severe. Alzheimer's disease is the most common cause of dementia in the UK.\u003c/paragraph-widget\u003e\u003c/page-widget\u003e","keywordPhrase":"alzheimer","articleAssets":[{"url":"https://cdn.magloft.com/reader/fonts/roboto-slab.css","extension":"css","contentType":"text/css"},{"url":"https://cdn.magloft.com/reader/fonts/open-sans.css","extension":"css","contentType":"text/css"},{"url":"https://cdn.magloft.com/pdf-import/1125/images/img_7-1.jpg","extension":"jpeg","contentType":"image/jpeg"}]},"publicationId":14882},"__N_SSG":true},"page":"/domains/[domain]/articles/[slug]","query":{"domain":"www.pharmafocus.com","slug":"tiziana-life-sciences-awarded-4m-grant-by-nih-to-study-anti-cd3"},"buildId":"U1LT7ce93wR6IyWFJCllT","isFallback":false,"gsp":true,"scriptLoader":[]}</script></body></html>