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<!DOCTYPE html> <html lang="en"><head> <meta charset="utf-8"> <title>Volume 13, Issue 13 - jca</title> <meta name="viewport" content="width=device-width, initial-scale=1" > <link rel="stylesheet" type="text/css" media="all" href="/ms/css/ivy.css?v=82"> <link rel="stylesheet" type="text/css" media="all and (min-width: 801px)" href="/ms/site/mainnew.css?v=15"> <link rel="stylesheet" type="text/css" media="all and (min-width: 801px)" href="/style.css?v=38"> <link rel="stylesheet" type="text/css" media="all and (max-width: 800px)" href="/ms/css/ivymobile.css?v=34" > <link rel="stylesheet" type="text/css" media="all and (max-width: 800px)" href="/ms/site/sitemobile.css?v=2" > <script src="/ms/java/function.js?v=43"></script> </head> <body id="main_body"> <div id="page_all"> <div id="container"> <div id="header"> <div id="logo" > <div > <span class='ivyjournal display_mobile'>Journal of Cancer</span>  </div> </div> <div id="key_visual"> <span class='button_grey impactfactor'>Impact factor<br>3.3</span><span class='display_pc' > <br><br><br><br></span> <span class='textlinkgrey display_pc' >ISSN: 1837-9664</span></div> </div> <div id="main_nav_container"> <ul id=main_nav_list><li><a href="/" >Home </a></li><li><a href="/about" >About </a></li><li><a href="/ms/author" >For Authors </a></li><li><a href="/ms/submit" >Submit Manuscript </a></li><li><a href="/ms/status" >Login </a></li><li><a href="/ms/feedback" >Contact </a></li></ul> <div class='topnav-right'> <a href='/ms/userlogin' title='My account'><img src='/ms/images/account.svg' alt='Account' height='24' width='24'> </a> </div> </div> <div id="main_container"> <div id="sub_container1"> <div id="sub_nav_container"> <ul class='sub_nav_list'><li><a href="/currentissue" >Current Issue </a></li><li><a href="/ms/archive/16" >Volume 16; 2025 </a></li><li><a href="/ms/archive/15" >Volume 15; 2024 </a></li><li><a href="/ms/archive/14" >Volume 14; 2023 </a></li><li><a href="/ms/archive/13" >Volume 13; 2022 </a></li><li><a href="/ms/archive/12" >Volume 12; 2021 </a></li><li><a href="/ms/archive" >Archive </a></li><li><a href="/editorial" >Editorial Board </a></li><li><a href="/ms/coverimage" >Cover Images </a></li><li><a href="/indexrank" >Index & Coverage </a></li><li><a href="/specialissue" >Special Issues </a></li></ul> <form method="post" action="/ms/mysearch" class="searchblock" > <input type="text" name="query" size="9" maxlength="255" value="" id="sbi" class="formfield" placeholder="Article title/doi"> <button type="submit" name="search" value="Search" id="sbb" title="Search article by title or doi"><img src='/ms/images/search.svg' alt='Search' height='24' width='24' style='vertical-align: middle;'></button> <input type="hidden" name="content" value="JCA1837-9664"> </form> <div class='sub_nav_space display_pc'></div> <div class="textcenter"> <p class="divboxbg"><a href="https://www.ijbs.com" class="textlink">International Journal of Biological Sciences</a></p> <p class="divboxbg"><a href="https://www.medsci.org" class="textlink">International Journal of Medical Sciences</a></p> <p class="divboxbg"><a href="https://www.thno.org" class="textlink">Theranostics</a></p> <p class="divboxbg"><a href="https://www.jgenomics.com" class="textlink">Journal of Genomics</a></p> <p class="divboxbg"><a href="https://www.ntno.org" class="textlink">Nanotheranostics</a></p> <a href="https://www.ncbi.nlm.nih.gov/pmc/journals/1305/" ><img src="/ms/images/pmclogo.gif" alt="PubMed Central" width="145" height="75" class="imagecenter" ></a> <p class="divboxbg abstract"> <img src="/ms/images/openaccess.jpg" width="145" height="54" alt="open access"> Global reach, higher impact</p> </div> </div> </div> <div id="sub_container2">  <div class='coverfig imageright' ><img src='cover/thumb/v13i13.jpg' alt='Front cover' onclick="openPopupFig('cover/v13i13.jpg');"> </div><p > <a class="boxnice" href="v13i12">◂ Last issue</a> <a class="boxnice" href="v13i14">Next issue ▸</a> <a class="boxnice" href="/ms/archive">Archive</a> <a class="boxnice" href="cover/v13i13.pdf">Cover PDF</a>   </p><p class="tocheading" style='clear:right;' >Volume 13 (13); 2022</p><p class='articlegroup' style='clear:right;' >Editorial Commentary</p><img class='clickfig' src='/v13/p3463/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3463/toc.jpg');"> <p><b>The most effective but largely ignored target for prostate cancer early detection and intervention</b> <br> Yan-gao Man, Ciaran Mannion, Anahid Jewett, Yi-Hsuan Hsiao, Aijun Liu, Andrzej Semczuk, Paul Zarogoulidis, Andrei B. Gapeev, Alessia Cimadamore, Peng Lee, Antonio Lopez-Beltran, Rodolfo Montironi, Francesco Massari, Xin Lu, Liang Cheng <br> <i>J. Cancer</i> 2022; 13(13): 3463-3475. doi:10.7150/jca.72973 <br> <a class="boxtext" href="/v13p3463.htm">Full text</a> <a class="boxtext" href="/v13p3463.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313040">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608211/">PMC</a></p><p class='articlegroup' style='clear:right;' >Research Papers</p><img class='clickfig' src='/v13/p3396/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3396/toc.jpg');"> <p><b>Real-world experience of safety and effectiveness of regorafenib for treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumors, and hepatocellular carcinoma: a post-marketing surveillance study in Korea</b> <br> Seung-Hoon Beom, Ki Beom Bae, Dae Young Zang, Joohee Bae, In Gyu Hwang, Hye Jin Kang, In Sook Woo, Byoung Yong Shim, Byung-Noe Bae, Jaekyung Cheon, Sang-Bo Oh, Joong-Bae Ahn <br> <i>J. Cancer</i> 2022; 13(13): 3396-3403. doi:10.7150/jca.74107 <br> <a class="boxtext" href="/v13p3396.htm">Full text</a> <a class="boxtext" href="/v13p3396.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313033">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608207/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3404/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3404/toc.jpg');"> <p><b>Early detection of colorectal cancer somatic mutations using cfDNA liquid biopsies in a murine carcinogenesis model</b> <br> Héctor Martínez-Gregorio, Clara Díaz-Velásquez, Mario Esaú Romero-Piña, Miguel Ruiz de la Cruz, Norma Laura Delgado-Buenrostro, Aldo de la Cruz-Montoya, Yolanda Irasema Chirino, Luis Ignacio Terrazas, Luis Alberto Medina, Felipe Vaca-Paniagua <br> <i>J. Cancer</i> 2022; 13(13): 3404-3414. doi:10.7150/jca.76516 <br> <a class="boxtext" href="/v13p3404.htm">Full text</a> <a class="boxtext" href="/v13p3404.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313038">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608204/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3415/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3415/toc.jpg');"> <p><b>Silibinin inhibits the migration, invasion and epithelial-mesenchymal transition of prostate cancer by activating the autophagic degradation of YAP</b> <br> Weichao Dan, Yizeng Fan, Tao Hou, Yi Wei, Bo Liu, Taotao Que, Bixin Yu, Jin Zeng, Lei Li <br> <i>J. Cancer</i> 2022; 13(13): 3415-3426. doi:10.7150/jca.63514 <br> <a class="boxtext" href="/v13p3415.htm">Full text</a> <a class="boxtext" href="/v13p3415.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313039">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608209/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3427/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3427/toc.jpg');"> <p><b>Oncologic Benefit of Adjuvant Therapy in Lateral Pelvic Lymph Node Metastasis following Neoadjuvant Chemoradiotherapy and Lateral Pelvic Lymph Node Dissection</b> <br> Yu-Juan Jiang, Si-Cheng Zhou, Jing-Hua Chen, Jian-Wei Liang <br> <i>J. Cancer</i> 2022; 13(13): 3427-3433. doi:10.7150/jca.77689 <br> <a class="boxtext" href="/v13p3427.htm">Full text</a> <a class="boxtext" href="/v13p3427.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313037">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608212/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3452/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3452/toc.jpg');"> <p><b>Risk factors of secondary cancer in nasopharyngeal carcinoma patients after radiotherapy</b> <br> Wen-Jie Wang, Miao Li, Xin-Bin Pan <br> <i>J. Cancer</i> 2022; 13(13): 3452-3462. doi:10.7150/jca.77768 <br> <a class="boxtext" href="/v13p3452.htm">Full text</a> <a class="boxtext" href="/v13p3452.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313032">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608213/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3477/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3477/toc.jpg');"> <p><b>Prognostic Impact of Ectopic Fat Deposition within Psoas Muscle in Stage IV Gastric Cancer Patients Undergoing Systemic Chemotherapy</b> <br> Takako Ikegami, Hiroki Nishikawa, Masahiro Goto, Fukutaro Shimamoto, Tetsuji Terazawa, Toshifumi Yamaguchi, Eiki Yamasaki, Ken Asaishi, Shiro Nakamura, Kazuhide Higuchi <br> <i>J. Cancer</i> 2022; 13(13): 3477-3484. doi:10.7150/jca.78407 <br> <a class="boxtext" href="/v13p3477.htm">Full text</a> <a class="boxtext" href="/v13p3477.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313034">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608208/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3485/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3485/toc.jpg');"> <p><b>What Causes Death in Esophageal Cancer Patients Other Than the Cancer Itself: A Large Population-Based Analysis</b> <br> Xueer Zheng, Anlai Zhang, Yao Xiao, Kaibo Guo, Leitao Sun, Shanming Ruan, Fang Fang <br> <i>J. Cancer</i> 2022; 13(13): 3485-3494. doi:10.7150/jca.78004 <br> <a class="boxtext" href="/v13p3485.htm">Full text</a> <a class="boxtext" href="/v13p3485.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313035">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608205/">PMC</a></p><p class='articlegroup' style='clear:right;' >Reviews</p><img class='clickfig' src='/v13/p3434/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3434/toc.jpg');"> <p><b>Clinical implications of the interaction between PD-1/PD-L1 and PI3K/AKT/mTOR pathway in progression and treatment of non-small cell lung cancer</b> <br> Zihan Quan, Yang Yang, Hongmei Zheng, Yuting Zhan, Jiadi Luo, Yue Ning, Songqing Fan <br> <i>J. Cancer</i> 2022; 13(13): 3434-3443. doi:10.7150/jca.77619 <br> <a class="boxtext" href="/v13p3434.htm">Full text</a> <a class="boxtext" href="/v13p3434.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313041">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608206/">PMC</a></p><hr class='clear'><img class='clickfig' src='/v13/p3444/toc.jpg' alt='Graphic abstract' onclick="openPopupFig('/v13/p3444/toc.jpg');"> <p><b>The pros and cons of the PCC staging system to guide surgical resectability and prognosis</b> <br> Pei Liu, Yinghui Song, Kashif shakoor, Chuang Peng, Sulai Liu <br> <i>J. Cancer</i> 2022; 13(13): 3444-3451. doi:10.7150/jca.76696 <br> <a class="boxtext" href="/v13p3444.htm">Full text</a> <a class="boxtext" href="/v13p3444.pdf">PDF</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pubmed/36313036">PubMed</a> <a class="boxtext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608210/">PMC</a></p>  <div id="popupFig" class="popupFig cursor-zoom-out"> <div id="popupFig-wrap" class="popupFig-wrap"> <img id="popupFigImage" src="" class="clickfig_max" alt="Popup Image" onclick="closePopupFig()"> </div> </div>  </div> <div id="footer_text"><hr class="nice"> <p>©2025 <a href="https://ivyspring.com" >Ivyspring International Publisher</a>. <a href="/ms/terms">Terms of use</a></p></div> </div> </div> </div> </body></html>