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Search results for: magnetic nanoparticle
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1779</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: magnetic nanoparticle</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1779</span> Investigation and Optimization of DNA Isolation Efficiency Using Ferrite-Based Magnetic Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T%C3%ADmea%20Gerzsenyi">Tímea Gerzsenyi</a>, <a href="https://publications.waset.org/abstracts/search?q=%C3%81gnes%20M.%20Ilosvai"> Ágnes M. Ilosvai</a>, <a href="https://publications.waset.org/abstracts/search?q=L%C3%A1szl%C3%B3%20Vanyorek"> László Vanyorek</a>, <a href="https://publications.waset.org/abstracts/search?q=Emma%20Sz%C5%91ri-Dorogh%C3%A1zi"> Emma Szőri-Dorogházi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> DNA isolation is a crucial step in many molecular biological applications for diagnostic and research purposes. However, traditional extraction requires toxic reagents, and commercially available kits are expensive, this leading to the recently wide-spread method, the magnetic nanoparticle (MNP)-based DNA isolation. Different ferrite containing MNPs were examined and compared in their plasmid DNA isolation efficiency. Among the tested MNPs, one has never been used for the extraction of plasmid molecules, marking a distinct application. pDNA isolation process was optimized for each type of nanoparticle and the best protocol was selected based on different criteria: DNA quantity, quality and integrity. With the best-performing magnetic nanoparticle, which excelled in all aspects, further tests were performed to recover genomic DNA from bacterial cells and a protocol was developed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DNA%20isolation" title="DNA isolation">DNA isolation</a>, <a href="https://publications.waset.org/abstracts/search?q=nanobiotechnology" title=" nanobiotechnology"> nanobiotechnology</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title=" magnetic nanoparticles"> magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=protocol%20optimization" title=" protocol optimization"> protocol optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=pDNA" title=" pDNA"> pDNA</a>, <a href="https://publications.waset.org/abstracts/search?q=gDNA" title=" gDNA"> gDNA</a> </p> <a href="https://publications.waset.org/abstracts/194630/investigation-and-optimization-of-dna-isolation-efficiency-using-ferrite-based-magnetic-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194630.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">9</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1778</span> Magnetic Nanoparticles for Cancer Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sachinkumar%20Patil">Sachinkumar Patil</a>, <a href="https://publications.waset.org/abstracts/search?q=Sonali%20Patil"> Sonali Patil</a>, <a href="https://publications.waset.org/abstracts/search?q=Shitalkumar%20Patil"> Shitalkumar Patil</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanoparticles played important role in the biomedicine. New advanced methods having great potential apllication in the diagnosis and therapy of cancer. Now a day’s magnetic nanoparticles used in cancer therapy. Cancer is the major disease causes death. Magnetic nanoparticles show response to the magnetic field on the basis of this property they are used in cancer therapy. Cancer treated with hyperthermia by using magnetic nanoparticles it is unconventional but more safe and effective method. Magnetic nanoparticles prepared by using different innovative techniques that makes particles in uniform size and desired effect. Magnetic nanoparticles already used as contrast media in magnetic resonance imaging. A magnetic nanoparticle has been great potential application in cancer diagnosis and treatment as well as in gene therapy. In this review we will discuss the progress in cancer therapy based on magnetic nanoparticles, mainly including magnetic hyperthermia, synthesis and characterization of magnetic nanoparticles, mechanism of magnetic nanoparticles and application of magnetic nanoparticles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title="magnetic nanoparticles">magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=synthesis" title=" synthesis"> synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer%20therapy" title=" cancer therapy"> cancer therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperthermia" title=" hyperthermia"> hyperthermia</a>, <a href="https://publications.waset.org/abstracts/search?q=application" title=" application"> application</a> </p> <a href="https://publications.waset.org/abstracts/31421/magnetic-nanoparticles-for-cancer-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31421.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">639</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1777</span> First-Principles Modeling of Nanoparticle Magnetization, Chaining, and Motion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pierce%20Radecki">Pierce Radecki</a>, <a href="https://publications.waset.org/abstracts/search?q=Pulkit%20Malik"> Pulkit Malik</a>, <a href="https://publications.waset.org/abstracts/search?q=Bharath%20Ramaswamy"> Bharath Ramaswamy</a>, <a href="https://publications.waset.org/abstracts/search?q=Ben%20Shapiro"> Ben Shapiro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ability to effectively design and test magnetic nanoparticles for controlled movement has been an elusive goal in the design of these particles. Magnetic nanoparticles of various characteristics have been created for use towards therapeutic effects, however the challenge of designing for controlled movement remains unmet. A step towards design in this aspect is a first principles model that captures and predicts the behaviors of particles in a magnetic field. The model is governed by four forces acting on the particles, the magnetic gradient, the dipole-dipole forces, the steric forces, and the viscous drag force. The particles are multi-core or single core, and incorporate a preferred magnetization axis. Particles exhibit behaviors, such as chaining, in simulations that are similar to those witnessed through experimentation. Currently, experimental results are being compared to the modeling results for verification of the model, through the analysis of chaining behaviors. This modeling system will be used in designing magnetic nanoparticles for specific chaining and movement behaviors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=controlled%20movement" title="controlled movement">controlled movement</a>, <a href="https://publications.waset.org/abstracts/search?q=modeling" title=" modeling"> modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title=" magnetic nanoparticles"> magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle%20design" title=" nanoparticle design"> nanoparticle design</a> </p> <a href="https://publications.waset.org/abstracts/47235/first-principles-modeling-of-nanoparticle-magnetization-chaining-and-motion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47235.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1776</span> Magnetic Properties of Nickel Oxide Nanoparticles in Superparamagnetic State</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Navneet%20Kaur">Navneet Kaur</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20D.%20Tiwari"> S. D. Tiwari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Superparamagnetism is an interesting phenomenon and observed in small particles of magnetic materials. It arises due to a reduction in particle size. In the superparamagnetic state, as the thermal energy overcomes magnetic anisotropy energy, the magnetic moment vector of particles flip their magnetization direction between states of minimum energy. Superparamagnetic nanoparticles have been attracting the researchers due to many applications such as information storage, magnetic resonance imaging, biomedical applications, and sensors. For information storage, thermal fluctuations lead to loss of data. So that nanoparticles should have high blocking temperature. And to achieve this, nanoparticles should have a higher magnetic moment and magnetic anisotropy constant. In this work, the magnetic anisotropy constant of the antiferromagnetic nanoparticles system is determined. Magnetic studies on nanoparticles of NiO (nickel oxide) are reported well. This antiferromagnetic nanoparticle system has high blocking temperature and magnetic anisotropy constant of order 105 J/m3. The magnetic study of NiO nanoparticles in the superparamagnetic region is presented. NiO particles of two different sizes, i.e., 6 and 8 nm, are synthesized using the chemical route. These particles are characterized by an x-ray diffractometer, transmission electron microscope, and superconducting quantum interference device magnetometry. The magnetization vs. applied magnetic field and temperature data for both samples confirm their superparamagnetic nature. The blocking temperature for 6 and 8 nm particles is found to be 200 and 172 K, respectively. Magnetization vs. applied magnetic field data of NiO is fitted to an appropriate magnetic expression using a non-linear least square fit method. The role of particle size distribution and magnetic anisotropy is taken in to account in magnetization expression. The source code is written in Python programming language. This fitting provides us the magnetic anisotropy constant for NiO and other magnetic fit parameters. The particle size distribution estimated matches well with the transmission electron micrograph. The value of magnetic anisotropy constants for 6 and 8 nm particles is found to be 1.42 X 105 and 1.20 X 105 J/m3, respectively. The obtained magnetic fit parameters are verified using the Neel model. It is concluded that the effect of magnetic anisotropy should not be ignored while studying the magnetization process of nanoparticles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anisotropy" title="anisotropy">anisotropy</a>, <a href="https://publications.waset.org/abstracts/search?q=superparamagnetic" title=" superparamagnetic"> superparamagnetic</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title=" nanoparticle"> nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetization" title=" magnetization"> magnetization</a> </p> <a href="https://publications.waset.org/abstracts/123236/magnetic-properties-of-nickel-oxide-nanoparticles-in-superparamagnetic-state" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/123236.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">134</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1775</span> Nonreciprocal Optical Effects in Plasmonic Nanoparticle Aggregates</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ward%20Brullot">Ward Brullot</a>, <a href="https://publications.waset.org/abstracts/search?q=Thierry%20Verbiest"> Thierry Verbiest</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nonreciprocal optical effects, such as Faraday rotation or magnetic circular dichroism, are very useful both for fundamental studies as for applications such as magnetic field sensors or optical isolators. In this study, we developed layer-by-layer deposited 20nm thick plasmonic nanoparticle aggregates consisting of gold, silver and magnetite nanoparticles that show broadband nonreciprocal asymmetric transmission. As such, the optical transmittance, or absorbance, depends on the direction of light propagation in the material, which means that looking from one direction or the other, more or less light passes through the sample. Theoretical analysis showed that strong electric quadrupole fields, which are electric field gradients, occur in the aggregates and that these quadrupole fields are responsible for the observed asymmetric transmission and the nonreciprocity of the effect. Apart from nonreciprocal asymmetric transmission, also other effects such as, but not limited to, optical rotation, circular dichroism or nonlinear optical responses were measured in the plasmonic nanoparticle aggregates and the influences of the intense electric quadrupole fields determined. In conclusion, the presence of strong electric quadrupole fields make the developed plasmonic nanoparticle aggregates ideal candidates for the study and application of various nonreciprocal optical effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asymmetric%20transmission" title="asymmetric transmission">asymmetric transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=electric%20quadrupoles" title=" electric quadrupoles"> electric quadrupoles</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle%20aggregates" title=" nanoparticle aggregates"> nanoparticle aggregates</a>, <a href="https://publications.waset.org/abstracts/search?q=nonreciprocity" title=" nonreciprocity"> nonreciprocity</a> </p> <a href="https://publications.waset.org/abstracts/33791/nonreciprocal-optical-effects-in-plasmonic-nanoparticle-aggregates" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33791.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">424</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1774</span> MHD Boundary Layer Flow of a Nanofluid Past a Wedge Shaped Wick in Heat Pipe</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziya%20Uddin">Ziya Uddin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper deals with the theoretical and numerical investigation of magneto-hydrodynamic boundary layer flow of a nano fluid past a wedge shaped wick in heat pipe used for the cooling of electronic components and different type of machines. To incorporate the effect of nanoparticle diameter, concentration of nanoparticles in the pure fluid, nano thermal layer formed around the nanoparticle and Brownian motion of nano particles etc., appropriate models are used for the effective thermal and physical properties of nano fluids. To model the rotation of nano particles inside the base fluid, microfluidics theory is used. In this investigation ethylene glycol (EG) based nanofluids, are taken into account. The non-linear equations governing the flow and heat transfer are solved by using a very effective particle swarm optimization technique along with Runge-Kutta method. The values of heat transfer coefficient are found for different parameters involved in the formulation viz. nanoparticle concentration, nanoparticle size, magnetic field and wedge angle etc. It is found that the wedge angle, presence of magnetic field, nanoparticle size and nanoparticle concentration etc. have prominent effects on fluid flow and heat transfer characteristics for the considered configuration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanofluids" title="nanofluids">nanofluids</a>, <a href="https://publications.waset.org/abstracts/search?q=wedge%20shaped%20wick" title=" wedge shaped wick"> wedge shaped wick</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20pipe" title=" heat pipe"> heat pipe</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20modeling" title=" numerical modeling"> numerical modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=particle%20swarm%20optimization" title=" particle swarm optimization"> particle swarm optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=nanofluid%20applications" title=" nanofluid applications"> nanofluid applications</a>, <a href="https://publications.waset.org/abstracts/search?q=Heat%20transfer" title=" Heat transfer"> Heat transfer</a> </p> <a href="https://publications.waset.org/abstracts/28316/mhd-boundary-layer-flow-of-a-nanofluid-past-a-wedge-shaped-wick-in-heat-pipe" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28316.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">390</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1773</span> Enhanced Magnetic Hyperthermic Efficiency of Ferrite Based Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20P.%20Borah">J. P. Borah</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20D.%20Raland"> R. D. Raland</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hyperthermia is one of many techniques used destroys cancerous cell. It uses the physical methods to heat certain organ or tissue delivering an adequate temperature in an appropriate period of time, to the entire tumor volume for achieving optimal therapeutic results. Magnetic Metal ferrites nanoparticles (MFe₂O₄ where M = Mn, Zn, Ni, Co, Mg, etc.) are one of the most potential candidates for hyperthermia due to their tunability, biocompatibility, chemical stability and notable ability to mediate high rate of heat induction. However, to obtain the desirable properties for these applications, it is important to optimize their chemical composition, structure and magnetic properties. These properties are mainly sensitive to cation distribution of tetrahedral and octahedral sites. Among the ferrites, zinc ferrite (ZnFe₂O₄) and Manganese ferrite ((MnFe₂O₄) is one of a strong candidate for hyperthermia application because Mn and zinc have a non-magnetic cation and therefore the magnetic property is determined only by the cation distribution of iron, which provides a better platform to manipulate or tailor the properties. In this talk, influence of doping and surfactant towards cation re-distribution leading to an enhancement of magnetic properties of ferrite nanoparticles will be demonstrated. The efficiency of heat generation in association with the enhanced magnetic property is also well discussed in this talk. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle" title="magnetic nanoparticle">magnetic nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperthermia" title=" hyperthermia"> hyperthermia</a>, <a href="https://publications.waset.org/abstracts/search?q=x-ray%20diffraction" title=" x-ray diffraction"> x-ray diffraction</a>, <a href="https://publications.waset.org/abstracts/search?q=TEM%20study" title=" TEM study"> TEM study</a> </p> <a href="https://publications.waset.org/abstracts/84359/enhanced-magnetic-hyperthermic-efficiency-of-ferrite-based-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84359.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">164</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1772</span> Nanoparticle-Based Histidine-Rich Protein-2 Assay for the Detection of the Malaria Parasite Plasmodium Falciparum </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yagahira%20E.%20Castro-Sesquen">Yagahira E. Castro-Sesquen</a>, <a href="https://publications.waset.org/abstracts/search?q=Chloe%20Kim"> Chloe Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Robert%20H.%20Gilman"> Robert H. Gilman</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20J.%20Sullivan"> David J. Sullivan</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20C.%20Searson"> Peter C. Searson </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diagnosis of severe malaria is particularly important in highly endemic regions since most patients are positive for parasitemia and treatment differs from non-severe malaria. Diagnosis can be challenging due to the prevalence of diseases with similar symptoms. Accurate diagnosis is increasingly important to avoid overprescribing antimalarial drugs, minimize drug resistance, and minimize costs. A nanoparticle-based assay for detection and quantification of Plasmodium falciparum histidine-rich protein 2 (HRP2) in urine and serum is reported. The assay uses magnetic beads conjugated with anti-HRP2 antibody for protein capture and concentration, and antibody-conjugated quantum dots for optical detection. Western Blot analysis demonstrated that magnetic beads allows the concentration of HRP2 protein in urine by 20-fold. The concentration effect was achieved because large volume of urine can be incubated with beads, and magnetic separation can be easily performed in minutes to isolate beads containing HRP2 protein. Magnetic beads and Quantum Dots 525 conjugated to anti-HRP2 antibodies allows the detection of low concentration of HRP2 protein (0.5 ng mL-1), and quantification in the range of 33 to 2,000 ng mL-1 corresponding to the range associated with non-severe to severe malaria. This assay can be easily adapted to a non-invasive point-of-care test for classification of severe malaria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HRP2%20protein" title="HRP2 protein">HRP2 protein</a>, <a href="https://publications.waset.org/abstracts/search?q=malaria" title=" malaria"> malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20beads" title=" magnetic beads"> magnetic beads</a>, <a href="https://publications.waset.org/abstracts/search?q=Quantum%20dots" title=" Quantum dots"> Quantum dots</a> </p> <a href="https://publications.waset.org/abstracts/40731/nanoparticle-based-histidine-rich-protein-2-assay-for-the-detection-of-the-malaria-parasite-plasmodium-falciparum" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40731.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1771</span> Magnetic Nanoparticles for Protein C Purification</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Duygu%20%C3%87imen">Duygu Çimen</a>, <a href="https://publications.waset.org/abstracts/search?q=Nilay%20Bereli"> Nilay Bereli</a>, <a href="https://publications.waset.org/abstracts/search?q=Adil%20Denizli"> Adil Denizli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study is to synthesis magnetic nanoparticles for purify protein C. For this aim, N-Methacryloyl-(L)-histidine methyl ester (MAH) containing 2-hydroxyethyl methacrylate (HEMA) based magnetic nanoparticles were synthesized by using micro-emulsion polymerization technique for templating protein C via metal chelation. The obtained nanoparticles were characterized with Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), zeta-size analysis and electron spin resonance (ESR) spectroscopy. After that, they were used for protein C purification from aqueous solution to evaluate/optimize the adsorption condition. Hereby, the effecting factors such as concentration, pH, ionic strength, temperature, and reusability were evaluated. As the last step, protein C was determined with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=immobilized%20metal%20affinity%20chromatography%20%28IMAC%29" title="immobilized metal affinity chromatography (IMAC)">immobilized metal affinity chromatography (IMAC)</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle" title=" magnetic nanoparticle"> magnetic nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=protein%20C" title=" protein C"> protein C</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyethyl%20methacrylate%20%28HEMA%29" title=" hydroxyethyl methacrylate (HEMA)"> hydroxyethyl methacrylate (HEMA)</a> </p> <a href="https://publications.waset.org/abstracts/30767/magnetic-nanoparticles-for-protein-c-purification" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30767.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1770</span> Structural and Magnetic Properties of Bi0.82La0.2Fe1-xCrxO3 Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Nematifar">H. Nematifar</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Sanavi%20Khoshnoud"> D. Sanavi Khoshnoud</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Feyz"> S. Feyz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bi0.82La0.2Fe1-xCrxO3 (BLFCxO, x = 0.0, 0.02, 0.05 and 0.08) nanoparticles were successfully synthesized by a sol-gel method. The X-ray diffraction (XRD) patterns indicate that the lattice parameters decrease for x ≤ 0.05, firstly, and then they increase for x > 0.05. A transformation from rhombohedral structure to orthorhombic structure occurs at x = 0.08. The transmission electron microscopy (TEM) analysis shows that the average nanoparticle size is about 60-70 nm. The remnant magnetisation (Mr) increases gradually with x to 0.02, then decreases with further increasing x up to 0.05, and finally enchases abruptly in x = 0.08. The coercivity (HC) increases gradually with x to 0.05, and then significantly reduced with increasing Cr substitution. The magnetic ordering temperature (TN) decreases with Cr doping concentration. The M-H curves of all samples exhibit a wasp-waist hysteresis loop in low magnetic region. This property can play an important role for the applications of some multiferroic nano-device. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=BiFeO3" title="BiFeO3">BiFeO3</a>, <a href="https://publications.waset.org/abstracts/search?q=sol-gel%20preparation" title=" sol-gel preparation"> sol-gel preparation</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20materials" title=" magnetic materials"> magnetic materials</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20analysis" title=" thermal analysis"> thermal analysis</a> </p> <a href="https://publications.waset.org/abstracts/16617/structural-and-magnetic-properties-of-bi082la02fe1-xcrxo3-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16617.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">311</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1769</span> Immobilized Iron Oxide Nanoparticles for Stem Cell Reconstruction in Magnetic Particle Imaging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kolja%20Them">Kolja Them</a>, <a href="https://publications.waset.org/abstracts/search?q=Johannes%20Salamon"> Johannes Salamon</a>, <a href="https://publications.waset.org/abstracts/search?q=Harald%20Ittrich"> Harald Ittrich</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Kaul"> Michael Kaul</a>, <a href="https://publications.waset.org/abstracts/search?q=Tobias%20Knopp"> Tobias Knopp</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Superparamagnetic iron oxide nanoparticles (SPIONs) are nanoscale magnets which can be biologically functionalized for biomedical applications. Stem cell therapies to repair damaged tissue, magnetic fluid hyperthermia for cancer therapy and targeted drug delivery based on SPIONs are prominent examples where the visualization of a preferably low concentrated SPION distribution is essential. In 2005 a new method for tomographic SPION imaging has been introduced. The method named magnetic particle imaging (MPI) takes advantage of the nanoparticles magnetization change caused by an oscillating, external magnetic field and allows to directly image the time-dependent nanoparticle distribution. The SPION magnetization can be changed by the electron spin dynamics as well as by a mechanical rotation of the nanoparticle. In this work different calibration methods in MPI are investigated for image reconstruction of magnetically labeled stem cells. It is shown that a calibration using rotationally immobilized SPIONs provides a higher quality of stem cell images with fewer artifacts than a calibration using mobile SPIONs. The enhancement of the image quality and the reduction of artifacts enables the localization and identification of a smaller number of magnetically labeled stem cells. This is important for future medical applications where low concentrations of functionalized SPIONs interacting with biological matter have to be localized. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomedical%20imaging" title="biomedical imaging">biomedical imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=iron%20oxide%20nanoparticles" title=" iron oxide nanoparticles"> iron oxide nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20particle%20imaging" title=" magnetic particle imaging"> magnetic particle imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=stem%20cell%20imaging" title=" stem cell imaging"> stem cell imaging</a> </p> <a href="https://publications.waset.org/abstracts/35704/immobilized-iron-oxide-nanoparticles-for-stem-cell-reconstruction-in-magnetic-particle-imaging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35704.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">464</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1768</span> Study of Magnetic Nanoparticles’ Endocytosis in a Single Cell Level</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jefunnie%20Matahum">Jefunnie Matahum</a>, <a href="https://publications.waset.org/abstracts/search?q=Yu-Chi%20Kuo"> Yu-Chi Kuo</a>, <a href="https://publications.waset.org/abstracts/search?q=Chao-Ming%20Su"> Chao-Ming Su</a>, <a href="https://publications.waset.org/abstracts/search?q=Tzong-Rong%20Ger"> Tzong-Rong Ger</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Magnetic cell labeling is of great importance in various applications in biomedical fields such as cell separation and cell sorting. Since analytical methods for quantification of cell uptake of magnetic nanoparticles (MNPs) are already well established, image analysis on single cell level still needs more characterization. This study reports an alternative non-destructive quantification methods of single-cell uptake of positively charged MNPs. Magnetophoresis experiments were performed to calculate the number of MNPs in a single cell. Mobility of magnetic cells and the area of intracellular MNP stained by Prussian blue were quantified by image processing software. ICP-MS experiments were also performed to confirm the internalization of MNPs to cells. Initial results showed that the magnetic cells incubated at 100 µg and 50 µg MNPs/mL concentration move at 18.3 and 16.7 µm/sec, respectively. There is also an increasing trend in the number and area of intracellular MNP with increasing concentration. These results could be useful in assessing the nanoparticle uptake in a single cell level. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title="magnetic nanoparticles">magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20cell" title=" single cell"> single cell</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetophoresis" title=" magnetophoresis"> magnetophoresis</a>, <a href="https://publications.waset.org/abstracts/search?q=image%20analysis" title=" image analysis"> image analysis</a> </p> <a href="https://publications.waset.org/abstracts/66948/study-of-magnetic-nanoparticles-endocytosis-in-a-single-cell-level" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66948.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1767</span> Nanoparticles Modification by Grafting Strategies for the Development of Hybrid Nanocomposites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Irati%20Barandiaran">Irati Barandiaran</a>, <a href="https://publications.waset.org/abstracts/search?q=Xabier%20Velasco-Iza"> Xabier Velasco-Iza</a>, <a href="https://publications.waset.org/abstracts/search?q=Galder%20Kortaberria"> Galder Kortaberria</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hybrid inorganic/organic nanostructured materials based on block copolymers are of considerable interest in the field of Nanotechnology, taking into account that these nanocomposites combine the properties of polymer matrix and the unique properties of the added nanoparticles. The use of block copolymers as templates offers the opportunity to control the size and the distribution of inorganic nanoparticles. This research is focused on the surface modification of inorganic nanoparticles to reach a good interface between nanoparticles and polymer matrices which hinders the nanoparticle aggregation. The aim of this work is to obtain a good and selective dispersion of Fe3O4 magnetic nanoparticles into different types of block copolymers such us, poly(styrene-b-methyl methacrylate) (PS-b-PMMA), poly(styrene-b-ε-caprolactone) (PS-b-PCL) poly(isoprene-b-methyl methacrylate) (PI-b-PMMA) or poly(styrene-b-butadiene-b-methyl methacrylate) (SBM) by using different grafting strategies. Fe3O4 magnetic nanoparticles have been surface-modified with polymer or block copolymer brushes following different grafting methods (grafting to, grafting from and grafting through) to achieve a selective location of nanoparticles into desired domains of the block copolymers. Morphology of fabricated hybrid nanocomposites was studied by means of atomic force microscopy (AFM) and with the aim to reach well-ordered nanostructured composites different annealing methods were used. Additionally, nanoparticle amount has been also varied in order to investigate the effect of the nanoparticle content in the morphology of the block copolymer. Nowadays different characterization methods were using in order to investigate magnetic properties of nanometer-scale electronic devices. Particularly, two different techniques have been used with the aim of characterizing synthesized nanocomposites. First, magnetic force microscopy (MFM) was used to investigate qualitatively the magnetic properties taking into account that this technique allows distinguishing magnetic domains on the sample surface. On the other hand, magnetic characterization by vibrating sample magnetometer and superconducting quantum interference device. This technique demonstrated that magnetic properties of nanoparticles have been transferred to the nanocomposites, exhibiting superparamagnetic behavior similar to that of the maghemite nanoparticles at room temperature. Obtained advanced nanostructured materials could found possible applications in the field of dye-sensitized solar cells and electronic nanodevices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=atomic%20force%20microscopy" title="atomic force microscopy">atomic force microscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=block%20copolymers" title=" block copolymers"> block copolymers</a>, <a href="https://publications.waset.org/abstracts/search?q=grafting%20techniques" title=" grafting techniques"> grafting techniques</a>, <a href="https://publications.waset.org/abstracts/search?q=iron%20oxide%20nanoparticles" title=" iron oxide nanoparticles"> iron oxide nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/56614/nanoparticles-modification-by-grafting-strategies-for-the-development-of-hybrid-nanocomposites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56614.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">262</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1766</span> Synthesis of Nanoparticle Mordenite Zeolite for Dimethyl Ether Carbonylation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zhang%20Haitao">Zhang Haitao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The different size of nanoparticle mordenite zeolites were prepared by adding different soft template during hydrothermal process for carbonylation of dimethyl ether (DME) to methyl acetate (MA). The catalysts were characterized by X-ray diffraction, Ar adsorption-desorption, high-resolution transmission electron microscopy, NH3-temperature programmed desorption, scanning electron microscopy and Thermogravimetric. The characterization results confirmed that mordenite zeolites with small nanoparticle showed more strong acid sites which was the active site for carbonylation thus promoting conversion of DME and MA selectivity. Furthermore, the nanoparticle mordenite had increased the mass transfer efficiency which could suppress the formation of coke. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanoparticle%20mordenite" title="nanoparticle mordenite">nanoparticle mordenite</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonylation" title=" carbonylation"> carbonylation</a>, <a href="https://publications.waset.org/abstracts/search?q=dimethyl%20ether" title=" dimethyl ether"> dimethyl ether</a>, <a href="https://publications.waset.org/abstracts/search?q=methyl%20acetate" title=" methyl acetate"> methyl acetate</a> </p> <a href="https://publications.waset.org/abstracts/120694/synthesis-of-nanoparticle-mordenite-zeolite-for-dimethyl-ether-carbonylation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/120694.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">139</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1765</span> The Influence of Reaction Parameters on Magnetic Properties of Synthesized Strontium Ferrite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Bahgat">M. Bahgat</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20M.%20Awan"> F. M. Awan</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20A.%20Hanafy"> H. A. Hanafy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The conventional ceramic route was utilized to prepare a hard magnetic powder (M-type strontium ferrite, SrFe12O19). The stoichiometric mixture of iron oxide and strontium carbonate were calcined at 1000°C and then fired at various temperatures. The influence of various reaction parameters such as mixing ratio, calcination temperature, firing temperature and firing time on the magnetic behaviors of the synthesized magnetic powder were investigated.The magnetic properties including Coercivity (Hc), Magnetic saturation (Ms), and Magnetic remnance (Mr) were measured by vibrating sample magnetometer. Morphologically the produced magnetic powder has a dense hexagonal grain shape structure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hard%20magnetic%20materials" title="hard magnetic materials">hard magnetic materials</a>, <a href="https://publications.waset.org/abstracts/search?q=ceramic%20route" title=" ceramic route"> ceramic route</a>, <a href="https://publications.waset.org/abstracts/search?q=strontium%20ferrite" title=" strontium ferrite"> strontium ferrite</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20properties" title=" magnetic properties"> magnetic properties</a> </p> <a href="https://publications.waset.org/abstracts/21878/the-influence-of-reaction-parameters-on-magnetic-properties-of-synthesized-strontium-ferrite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21878.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">693</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1764</span> Multifunctional Bismuth-Based Nanoparticles as Theranostic Agent for Imaging and Radiation Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Azimeh%20Rajaee">Azimeh Rajaee</a>, <a href="https://publications.waset.org/abstracts/search?q=Lingyun%20Zhao"> Lingyun Zhao</a>, <a href="https://publications.waset.org/abstracts/search?q=Shi%20Wang"> Shi Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Yaqiang%20Liu"> Yaqiang Liu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years many studies have been focused on bismuth-based nanoparticles as radiosensitizer and contrast agent in radiation therapy and imaging due to the high atomic number (Z = 82), high photoelectric absorption, low cost, and low toxicity. This study aims to introduce a new multifunctional bismuth-based nanoparticle as a theranostic agent for radiotherapy, computed tomography (CT) and magnetic resonance imaging (MRI). We synthesized bismuth ferrite (BFO, BiFeO3) nanoparticles by sol-gel method and surface of the nanoparticles were modified by Polyethylene glycol (PEG). After proved biocompatibility of the nanoparticles, the ability of them as contract agent in Computed tomography (CT) and magnetic resonance imaging (MRI) was investigated. The relaxation time rate (R2) in MRI and Hounsfield unit (HU) in CT imaging were increased with the concentration of the nanoparticles. Moreover, the effect of nanoparticles on dose enhancement in low energy was investigated by clonogenic assay. According to clonogenic assay, sensitizer enhancement ratios (SERs) were obtained as 1.35 and 1.76 for nanoparticle concentrations of 0.05 mg/ml and 0.1 mg/ml, respectively. In conclusion, our experimental results demonstrate that the multifunctional nanoparticles have the ability to employ as multimodal imaging and therapy to enhance theranostic efficacy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecular%20imaging" title="molecular imaging">molecular imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=nanomedicine" title=" nanomedicine"> nanomedicine</a>, <a href="https://publications.waset.org/abstracts/search?q=radiotherapy" title=" radiotherapy"> radiotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=theranostics" title=" theranostics"> theranostics</a> </p> <a href="https://publications.waset.org/abstracts/95005/multifunctional-bismuth-based-nanoparticles-as-theranostic-agent-for-imaging-and-radiation-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95005.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">317</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1763</span> Superoxide Dismutase Activity of Male Rats after Administration of Extract and Nanoparticle of Ginger Torch Flower</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tresna%20Lestari">Tresna Lestari</a>, <a href="https://publications.waset.org/abstracts/search?q=Tita%20Nofianti"> Tita Nofianti</a>, <a href="https://publications.waset.org/abstracts/search?q=Ade%20Yeni%20Aprilia"> Ade Yeni Aprilia</a>, <a href="https://publications.waset.org/abstracts/search?q=Lilis%20Tuslinah"> Lilis Tuslinah</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruswanto%20Ruswanto"> Ruswanto Ruswanto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanoparticle formulation is often used to improve drug absorptivity, thus increasing the sharpness of the action. Ginger torch flower extract was formulated into nanoparticle form using poloxamer 1, 3 and 5%. The nanoparticle was then characterized by its particle size, polydispersity index, zeta potential, entrapment efficiency and morphological form by SEM. The result shows that nanoparticle formulations have particle size 134.7-193.1 nm, polydispersity index less than 0.5 for all formulations, zeta potential -41.0 - (-24.3) mV and entrapment efficiency 89.93-97.99 against flavonoid content with a soft surface and spherical form of particles. Methanolic extract of ginger torch flower could enhance superoxide dismutase activity by 1,3183 U/mL in male rats. Nanoparticle formulation of ginger torch extract is expected to increase the capability of the drug to enhance superoxide dismutase activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=superoxide%20dismutase" title="superoxide dismutase">superoxide dismutase</a>, <a href="https://publications.waset.org/abstracts/search?q=ginger%20torch%20flower" title=" ginger torch flower"> ginger torch flower</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title=" nanoparticle"> nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=poloxamer" title=" poloxamer"> poloxamer</a> </p> <a href="https://publications.waset.org/abstracts/91992/superoxide-dismutase-activity-of-male-rats-after-administration-of-extract-and-nanoparticle-of-ginger-torch-flower" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91992.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">159</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1762</span> Enhancement Effect of Superparamagnetic Iron Oxide Nanoparticle-Based MRI Contrast Agent at Different Concentrations and Magnetic Field Strengths</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bimali%20Sanjeevani%20Weerakoon">Bimali Sanjeevani Weerakoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Toshiaki%20Osuga"> Toshiaki Osuga</a>, <a href="https://publications.waset.org/abstracts/search?q=Takehisa%20Konishi"> Takehisa Konishi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Magnetic Resonance Imaging Contrast Agents (MRI-CM) are significant in the clinical and biological imaging as they have the ability to alter the normal tissue contrast, thereby affecting the signal intensity to enhance the visibility and detectability of images. Superparamagnetic Iron Oxide (SPIO) nanoparticles, coated with dextran or carboxydextran are currently available for clinical MR imaging of the liver. Most SPIO contrast agents are T2 shortening agents and Resovist (Ferucarbotran) is one of a clinically tested, organ-specific, SPIO agent which has a low molecular carboxydextran coating. The enhancement effect of Resovist depends on its relaxivity which in turn depends on factors like magnetic field strength, concentrations, nanoparticle properties, pH and temperature. Therefore, this study was conducted to investigate the impact of field strength and different contrast concentrations on enhancement effects of Resovist. The study explored the MRI signal intensity of Resovist in the physiological range of plasma from T2-weighted spin echo sequence at three magnetic field strengths: 0.47 T (r1=15, r2=101), 1.5 T (r1=7.4, r2=95), and 3 T (r1=3.3, r2=160) and the range of contrast concentrations by a mathematical simulation. Relaxivities of r1 and r2 (L mmol-1 Sec-1) were obtained from a previous study and the selected concentrations were 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 2.0, and 3.0 mmol/L. T2-weighted images were simulated using TR/TE ratio as 2000 ms /100 ms. According to the reference literature, with increasing magnetic field strengths, the r1 relaxivity tends to decrease while the r2 did not show any systematic relationship with the selected field strengths. In parallel, this study results revealed that the signal intensity of Resovist at lower concentrations tends to increase than the higher concentrations. The highest reported signal intensity was observed in the low field strength of 0.47 T. The maximum signal intensities for 0.47 T, 1.5 T and 3 T were found at the concentration levels of 0.05, 0.06 and 0.05 mmol/L, respectively. Furthermore, it was revealed that, the concentrations higher than the above, the signal intensity was decreased exponentially. An inverse relationship can be found between the field strength and T2 relaxation time, whereas, the field strength was increased, T2 relaxation time was decreased accordingly. However, resulted T2 relaxation time was not significantly different between 0.47 T and 1.5 T in this study. Moreover, a linear correlation of transverse relaxation rates (1/T2, s–1) with the concentrations of Resovist can be observed. According to these results, it can conclude that the concentration of SPIO nanoparticle contrast agents and the field strengths of MRI are two important parameters which can affect the signal intensity of T2-weighted SE sequence. Therefore, when MR imaging those two parameters should be considered prudently. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Concentration" title="Concentration">Concentration</a>, <a href="https://publications.waset.org/abstracts/search?q=resovist" title=" resovist"> resovist</a>, <a href="https://publications.waset.org/abstracts/search?q=field%20strength" title=" field strength"> field strength</a>, <a href="https://publications.waset.org/abstracts/search?q=relaxivity" title=" relaxivity"> relaxivity</a>, <a href="https://publications.waset.org/abstracts/search?q=signal%20intensity" title=" signal intensity"> signal intensity</a> </p> <a href="https://publications.waset.org/abstracts/37638/enhancement-effect-of-superparamagnetic-iron-oxide-nanoparticle-based-mri-contrast-agent-at-different-concentrations-and-magnetic-field-strengths" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37638.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">352</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1761</span> Antibody-Conjugated Nontoxic Arginine-Doped Fe3O4 Nanoparticles for Magnetic Circulating Tumor Cells Separation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20Kashanian">F. Kashanian</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20M.%20Masoudi"> M. M. Masoudi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Akbari"> A. Akbari</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Shamloo"> A. Shamloo</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20R.%20Zand"> M. R. Zand</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20S.%20Salehi"> S. S. Salehi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nano-sized materials present new opportunities in biology and medicine and they are used as biomedical tools for investigation, separation of molecules and cells. To achieve more effective cancer therapy, it is essential to select cancer cells exactly. This research suggests that using the antibody-functionalized nontoxic Arginine-doped magnetic nanoparticles (A-MNPs), has been prosperous in detection, capture, and magnetic separation of circulating tumor cells (CTCs) in tumor tissue. In this study, A-MNPs were synthesized via a simple precipitation reaction and directly immobilized Ep-CAM EBA-1 antibodies over superparamagnetic A-MNPs for Mucin BCA-225 in breast cancer cell. The samples were characterized by vibrating sample magnetometer (VSM), FT-IR spectroscopy, Tunneling Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM). These antibody-functionalized nontoxic A-MNPs were used to capture breast cancer cell. Through employing a strong permanent magnet, the magnetic separation was achieved within a few seconds. Antibody-Conjugated nontoxic Arginine-doped Fe<sub>3</sub>O<sub>4</sub> nanoparticles have the potential for the future study to capture CTCs which are released from tumor tissue and for drug delivery, and these results demonstrate that the antibody-conjugated A-MNPs can be used in magnetic hyperthermia techniques for cancer treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tumor%20tissue" title="tumor tissue">tumor tissue</a>, <a href="https://publications.waset.org/abstracts/search?q=antibody" title=" antibody"> antibody</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle" title=" magnetic nanoparticle"> magnetic nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=CTCs%20capturing" title=" CTCs capturing"> CTCs capturing</a> </p> <a href="https://publications.waset.org/abstracts/67417/antibody-conjugated-nontoxic-arginine-doped-fe3o4-nanoparticles-for-magnetic-circulating-tumor-cells-separation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67417.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">360</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1760</span> Analyzing Nonsimilar Convective Heat Transfer in Copper/Alumina Nanofluid with Magnetic Field and Thermal Radiations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdulmohsen%20Alruwaili">Abdulmohsen Alruwaili</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A partial differential system featuring momentum and energy balance is often used to describe simulations of flow initiation and thermal shifting in boundary layers. The buoyancy force in terms of temperature is factored in the momentum balance equation. Buoyancy force causes the flow quantity to fluctuate along the streamwise direction 𝑋; therefore, the problem can be, to our best knowledge, analyzed through nonsimilar modeling. In this analysis, a nonsimilar model is evolved for radiative mixed convection of a magnetized power-law nanoliquid flow on top of a vertical plate installed in a stationary fluid. The upward linear stretching initiated the flow in the vertical direction. Assuming nanofluids are composite of copper (Cu) and alumina (Al₂O₃) nanoparticles, the viscous dissipation in this case is negligible. The nonsimilar system is dealt with analytically by local nonsimilarity (LNS) via numerical algorithm bvp4c. Surface temperature and flow field are shown visually in relation to factors like mixed convection, magnetic field strength, nanoparticle volume fraction, radiation parameters, and Prandtl number. The repercussions of magnetic and mixed convection parameters on the rate of energy transfer and friction coefficient are represented in tabular forms. The results obtained are compared to the published literature. It is found that the existence of nanoparticles significantly improves the temperature profile of considered nanoliquid. It is also observed that when the estimates of the magnetic parameter increase, the velocity profile decreases. Enhancement in nanoparticle concentration and mixed convection parameter improves the velocity profile. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanofluid" title="nanofluid">nanofluid</a>, <a href="https://publications.waset.org/abstracts/search?q=power%20law%20model" title=" power law model"> power law model</a>, <a href="https://publications.waset.org/abstracts/search?q=mixed%20convection" title=" mixed convection"> mixed convection</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20radiation" title=" thermal radiation"> thermal radiation</a> </p> <a href="https://publications.waset.org/abstracts/189314/analyzing-nonsimilar-convective-heat-transfer-in-copperalumina-nanofluid-with-magnetic-field-and-thermal-radiations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189314.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">32</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1759</span> Analytical Model for Vacuum Cathode Arcs in an Oblique Magnetic Field</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20W.%20Chen">P. W. Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20T.%20Chang"> C. T. Chang</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Peng"> Y. Peng</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Y.%20Wu"> J. Y. Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20J.%20Jan"> D. J. Jan</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.%20Manirul%20Ali"> Md. Manirul Ali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the last decade, the nature of cathode spot splitting and the current per spot depended on an oblique magnetic field was investigated. This model for cathode current splitting is developed that we have investigated with relationship the magnetic pressures produced by kinetic pressure, self-magnetic pressure, and changed with an external magnetic field. We propose a theoretical model that has been established to an external magnetic field with components normal and tangential to the cathode surface influenced on magnetic pressure strength. We mainly focus on developed to understand the current per spot influenced with the tangential magnetic field strength and normal magnetic field strength. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cathode%20spot" title="cathode spot">cathode spot</a>, <a href="https://publications.waset.org/abstracts/search?q=vacuum%20arc%20discharge" title=" vacuum arc discharge"> vacuum arc discharge</a>, <a href="https://publications.waset.org/abstracts/search?q=oblique%20magnetic%20field" title=" oblique magnetic field"> oblique magnetic field</a>, <a href="https://publications.waset.org/abstracts/search?q=tangential%20magnetic%20field" title=" tangential magnetic field"> tangential magnetic field</a> </p> <a href="https://publications.waset.org/abstracts/52606/analytical-model-for-vacuum-cathode-arcs-in-an-oblique-magnetic-field" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52606.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">324</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1758</span> Consideration of Magnetic Lines of Force as Magnets Produced by Percussion Waves</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Angel%20P%C3%A9rez%20S%C3%A1nchez">Angel Pérez Sánchez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Consider magnetic lines of force as a vector magnetic current was introduced by convention around 1830. But this leads to a dead end in traditional physics, and quantum explanations must be referred to explain the magnetic phenomenon. However, a study of magnetic lines as percussive waves leads to other paths capable of interpreting magnetism through traditional physics. Methodology: Brick used in the experiment: two parallel electric current cables attract each other if current goes in the same direction and its application at a microscopic level inside magnets. Significance: Consideration of magnetic lines as magnets themselves would mean a paradigm shift in the study of magnetism and open the way to provide solutions to mysteries of magnetism until now only revealed by quantum mechanics. Major findings: discover how a magnetic field is created, as well as reason how magnetic attraction and repulsion work, understand how magnets behave when splitting them, and reveal the impossibility of a Magnetic Monopole. All of this is presented as if it were a symphony in which all the notes fit together perfectly to create a beautiful, smart, and simple work. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=magnetic%20lines%20of%20force" title="magnetic lines of force">magnetic lines of force</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20field" title=" magnetic field"> magnetic field</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20attraction%20and%20repulsion" title=" magnetic attraction and repulsion"> magnetic attraction and repulsion</a>, <a href="https://publications.waset.org/abstracts/search?q=magnet%20split" title=" magnet split"> magnet split</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20monopole" title=" magnetic monopole"> magnetic monopole</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20lines%20of%20force%20as%20magnets" title=" magnetic lines of force as magnets"> magnetic lines of force as magnets</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20lines%20of%20force%20as%20waves" title=" magnetic lines of force as waves"> magnetic lines of force as waves</a> </p> <a href="https://publications.waset.org/abstracts/172916/consideration-of-magnetic-lines-of-force-as-magnets-produced-by-percussion-waves" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172916.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">90</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1757</span> Paper-Based Colorimetric Sensor Utilizing Peroxidase-Mimicking Magnetic Nanoparticles Conjugated with Aptamers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Min-Ah%20Woo">Min-Ah Woo</a>, <a href="https://publications.waset.org/abstracts/search?q=Min-Cheol%20Lim"> Min-Cheol Lim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun-Joo%20Chang"> Hyun-Joo Chang</a>, <a href="https://publications.waset.org/abstracts/search?q=Sung-Wook%20Choi"> Sung-Wook Choi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We developed a paper-based colorimetric sensor utilizing magnetic nanoparticles conjugated with aptamers (MNP-Apts) against <em>E. coli</em> O157:H7. The MNP-Apts were applied to a test sample solution containing the target cells, and the solution was simply dropped onto PVDF (polyvinylidene difluoride) membrane. The membrane moves the sample radially to form the sample spots of different compounds as concentric rings, thus the MNP-Apts on the membrane enabled specific recognition of the target cells through a color ring generation by MNP-promoted colorimetric reaction of TMB (3,3',5,5'-tetramethylbenzidine) and H<sub>2</sub>O<sub>2</sub>. This method could be applied to rapidly and visually detect various bacterial pathogens in less than 1 h without cell culturing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aptamer" title="aptamer">aptamer</a>, <a href="https://publications.waset.org/abstracts/search?q=colorimetric%20sensor" title=" colorimetric sensor"> colorimetric sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20coli%20O157%3AH7" title=" E. coli O157:H7"> E. coli O157:H7</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle" title=" magnetic nanoparticle"> magnetic nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=polyvinylidene%20difluoride" title=" polyvinylidene difluoride"> polyvinylidene difluoride</a> </p> <a href="https://publications.waset.org/abstracts/51070/paper-based-colorimetric-sensor-utilizing-peroxidase-mimicking-magnetic-nanoparticles-conjugated-with-aptamers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51070.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">450</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1756</span> Integrated Mathematical Modeling and Advance Visualization of Magnetic Nanoparticle for Drug Delivery, Drug Release and Effects to Cancer Cell Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Norma%20Binti%20Alias">Norma Binti Alias</a>, <a href="https://publications.waset.org/abstracts/search?q=Che%20Rahim%20Che%20The"> Che Rahim Che The</a>, <a href="https://publications.waset.org/abstracts/search?q=Norfarizan%20Mohd%20Said"> Norfarizan Mohd Said</a>, <a href="https://publications.waset.org/abstracts/search?q=Sakinah%20Abdul%20Hanan"> Sakinah Abdul Hanan</a>, <a href="https://publications.waset.org/abstracts/search?q=Akhtar%20Ali"> Akhtar Ali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper discusses on the transportation of magnetic drug targeting through blood within vessels, tissues and cells. There are three integrated mathematical models to be discussed and analyze the concentration of drug and blood flow through magnetic nanoparticles. The cell therapy brought advancement in the field of nanotechnology to fight against the tumors. The systematic therapeutic effect of Single Cells can reduce the growth of cancer tissue. The process of this nanoscale phenomena system is able to measure and to model, by identifying some parameters and applying fundamental principles of mathematical modeling and simulation. The mathematical modeling of single cell growth depends on three types of cell densities such as proliferative, quiescent and necrotic cells. The aim of this paper is to enhance the simulation of three types of models. The first model represents the transport of drugs by coupled partial differential equations (PDEs) with 3D parabolic type in a cylindrical coordinate system. This model is integrated by Non-Newtonian flow equations, leading to blood liquid flow as the medium for transportation system and the magnetic force on the magnetic nanoparticles. The interaction between the magnetic force on drug with magnetic properties produces induced currents and the applied magnetic field yields forces with tend to move slowly the movement of blood and bring the drug to the cancer cells. The devices of nanoscale allow the drug to discharge the blood vessels and even spread out through the tissue and access to the cancer cells. The second model is the transport of drug nanoparticles from the vascular system to a single cell. The treatment of the vascular system encounters some parameter identification such as magnetic nanoparticle targeted delivery, blood flow, momentum transport, density and viscosity for drug and blood medium, intensity of magnetic fields and the radius of the capillary. Based on two discretization techniques, finite difference method (FDM) and finite element method (FEM), the set of integrated models are transformed into a series of grid points to get a large system of equations. The third model is a single cell density model involving the three sets of first order PDEs equations for proliferating, quiescent and necrotic cells change over time and space in Cartesian coordinate which regulates under different rates of nutrients consumptions. The model presents the proliferative and quiescent cell growth depends on some parameter changes and the necrotic cells emerged as the tumor core. Some numerical schemes for solving the system of equations are compared and analyzed. Simulation and computation of the discretized model are supported by Matlab and C programming languages on a single processing unit. Some numerical results and analysis of the algorithms are presented in terms of informative presentation of tables, multiple graph and multidimensional visualization. As a conclusion, the integrated of three types mathematical modeling and the comparison of numerical performance indicates that the superior tool and analysis for solving the complete set of magnetic drug delivery system which give significant effects on the growth of the targeted cancer cell. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mathematical%20modeling" title="mathematical modeling">mathematical modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=visualization" title=" visualization"> visualization</a>, <a href="https://publications.waset.org/abstracts/search?q=PDE%20models" title=" PDE models"> PDE models</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle%20drug%20delivery%20model" title=" magnetic nanoparticle drug delivery model"> magnetic nanoparticle drug delivery model</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20release%20model" title=" drug release model"> drug release model</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20cell%20effects" title=" single cell effects"> single cell effects</a>, <a href="https://publications.waset.org/abstracts/search?q=avascular%20tumor%20growth" title=" avascular tumor growth"> avascular tumor growth</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20analysis" title=" numerical analysis"> numerical analysis</a> </p> <a href="https://publications.waset.org/abstracts/34967/integrated-mathematical-modeling-and-advance-visualization-of-magnetic-nanoparticle-for-drug-delivery-drug-release-and-effects-to-cancer-cell-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34967.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">428</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1755</span> Magnetic and Optical Properties of GaFeMnN</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.Abbad">A.Abbad</a>, <a href="https://publications.waset.org/abstracts/search?q=H.A.Bentounes"> H.A.Bentounes</a>, <a href="https://publications.waset.org/abstracts/search?q=W.Benstaali"> W.Benstaali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The full-potential linearized augmented plane wave method (FP-LAPW) within the Generalized Gradient Approximation (GGA) is used to calculate the magnetic and optical properties of quaternary GaFeMnN. The results show that the compound becomes magnetic and half metallic and there is an apparition of peaks at low frequencies for the optical properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=FP-LAPW" title="FP-LAPW">FP-LAPW</a>, <a href="https://publications.waset.org/abstracts/search?q=LSDA" title=" LSDA"> LSDA</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20moment" title=" magnetic moment"> magnetic moment</a>, <a href="https://publications.waset.org/abstracts/search?q=reflectivity" title=" reflectivity "> reflectivity </a> </p> <a href="https://publications.waset.org/abstracts/26313/magnetic-and-optical-properties-of-gafemnn" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26313.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">524</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1754</span> Increased Retention of Nanoparticle by Small Molecule Inhibitor in Cancer Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Neha%20Singh">Neha Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Nowadays, the nanoparticle is gaining unexceptional attention in targeted drug delivery. But before proceeding to this episode of accomplishment, the journey and closure of these nanoparticles inside the cells should be disentangle. Being foreign for the cells, nanoparticles will easily getcleared off without any effective outcome. As the cancer cells withhold these nanoparticles for a longer period of time, more will be the drug’s effect. Chlorpromazine is a cationic amphiphilic drug which is believed to inhibit clathrin-coated pit formation by a reversible translocation of clathrin and its adapter proteins from the plasma membrane to intracellular vesicles. Chlorpromazine has a role in increasing the retention of nanoparticles in cancer cells. The mechanism of action how this small molecule increases the retention of nanoparticles is still uncovered. Method: Polymeric nanoparticle (PLGA) with Cyanine3.5 dye were synthesized by solvent evaporation method and characterized for size and zeta potential. FTIR was also done. Pulse and chase studies with and without inhibitor were done to check the retention of nanoparticle using fluorescence microscopy. Mean fluorescence intensity was measured by ImageJ software. Results: Increased retention of nanoparticle with inhibitor was observed in both pulse and chase studies. Conclusion: Our results demonstrate that by repurposing these small molecule inhibitor, we can increase the retention of nanoparticle at the targeted site. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title="nanoparticle">nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=endocytosis" title=" endocytosis"> endocytosis</a>, <a href="https://publications.waset.org/abstracts/search?q=clathrin%20%20inhibitor" title=" clathrin inhibitor"> clathrin inhibitor</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer%20cell" title=" cancer cell"> cancer cell</a> </p> <a href="https://publications.waset.org/abstracts/154283/increased-retention-of-nanoparticle-by-small-molecule-inhibitor-in-cancer-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154283.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">105</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1753</span> On the Influence of the Metric Space in the Critical Behavior of Magnetic Temperature</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20C.%20Ria%C3%B1o-Rojas">J. C. Riaño-Rojas</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20D.%20Alzate-Cardona"> J. D. Alzate-Cardona</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Restrepo-Parra"> E. Restrepo-Parra</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this work, a study of generic magnetic nanoparticles varying the metric space is presented. As the metric space is changed, the nanoparticle form and the inner product are also varied, since the energetic scale is not conserved. This study is carried out using Monte Carlo simulations combined with the Wolff embedding and Metropolis algorithms. The Metropolis algorithm is used at high temperature regions to reach the equilibrium quickly. The Wolff embedding algorithm is used at low and critical temperature regions in order to reduce the critical slowing down phenomenon. The ions number is kept constant for the different forms and the critical temperatures using finite size scaling are found. We observed that critical temperatures don't exhibit significant changes when the metric space was varied. Additionally, the effective dimension according the metric space was determined. A study of static behavior for reaching the static critical exponents was developed. The objective of this work is to observe the behavior of the thermodynamic quantities as energy, magnetization, specific heat, susceptibility and Binder's cumulants at the critical region, in order to demonstrate if the magnetic nanoparticles describe their magnetic interactions in the Euclidean space or if there is any correspondence in other metric spaces. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title="nanoparticles">nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=metric" title=" metric"> metric</a>, <a href="https://publications.waset.org/abstracts/search?q=Monte%20Carlo" title=" Monte Carlo"> Monte Carlo</a>, <a href="https://publications.waset.org/abstracts/search?q=critical%20behaviour" title=" critical behaviour"> critical behaviour</a> </p> <a href="https://publications.waset.org/abstracts/29244/on-the-influence-of-the-metric-space-in-the-critical-behavior-of-magnetic-temperature" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29244.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">515</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1752</span> Antioxidant Activity of Nanoparticle of Etlingera elatior (Jack) R.M.Sm Flower Extract on Liver and Kidney of Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tita%20Nofianti">Tita Nofianti</a>, <a href="https://publications.waset.org/abstracts/search?q=Tresna%20Lestari"> Tresna Lestari</a>, <a href="https://publications.waset.org/abstracts/search?q=Ade%20Y.%20Aprillia"> Ade Y. Aprillia</a>, <a href="https://publications.waset.org/abstracts/search?q=Lilis%20Tuslinah"> Lilis Tuslinah</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruswanto%20Ruswanto"> Ruswanto Ruswanto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanoparticle technology gives a chance for drugs, especially natural based product, to give better activities than in its macromolecule form. The ginger torch is known to have activities as an antioxidant, antimicrobial, anticancer, etc. In this research, ginger torch flower extract was nanoparticlized using poloxamer 1, 3, and 5%. Nanoparticle was charaterized for its particle size, polydispersity index, zeta potential, entrapment efficiency, and morphological form by SEM (scanning electron microscope). The result shows that nanoparticle formulations have particle size 134.7-193.1 nm, polydispersity index is less than 0.5 for all formulations, zeta potential is -41.0 to (-24.3) mV, and entrapment efficiency is 89.93 to 97.99 against flavonoid content with a soft surface and spherical form of particles. Methanolic extract of ginger torch flower could enhance superoxide dismutase activity by 1,3183 U/mL in male rats. Nanoparticle formulation of ginger torch extract is expected to increase the capability of drug to enhance superoxide dismutase activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=superoxide%20dismutase" title="superoxide dismutase">superoxide dismutase</a>, <a href="https://publications.waset.org/abstracts/search?q=ginger%20torch%20flower" title=" ginger torch flower"> ginger torch flower</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title=" nanoparticle"> nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=poloxamer" title=" poloxamer "> poloxamer </a> </p> <a href="https://publications.waset.org/abstracts/92307/antioxidant-activity-of-nanoparticle-of-etlingera-elatior-jack-rmsm-flower-extract-on-liver-and-kidney-of-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92307.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">207</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1751</span> First Principle Calculation of The Magnetic Properties of Mn-doped 6H-SiC</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Al%20Azri">M. Al Azri</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Elzain"> M. Elzain</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Bouziane"> K. Bouziane</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20M.%20Ch%C3%A9rif"> S. M. Chérif</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The electronic and magnetic properties of 6H-SiC with Mn impurities have been calculated using ab-initio calculations. Various configurations of Mn sites and Si and C vacancies were considered. The magnetic coupling between the two Mn atoms at substitutional and interstitials sites with and without vacancies is studied as a function of Mn atoms interatomic distance. It was found that the magnetic interaction energy decreases with increasing distance between the magnetic atoms. The energy levels appearing in the band gap due to vacancies and due to Mn impurities are determined. The calculated DOS’s are used to analyze the nature of the exchange interaction between the impurities. The band coupling model based on the p-d and d-d level repulsions between Mn and SiC has been used to describe the magnetism observed in each configuration. Furthermore, the impacts of applying U to Mn-d orbital on the magnetic moment have also been investigated. The results are used to understand the experimental data obtained on Mn- 6H-SiC (as-implanted and as –annealed) for various Mn concentration (CMn = 0.7%, 1.6%, 7%). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ab-initio%20calculations" title="ab-initio calculations">ab-initio calculations</a>, <a href="https://publications.waset.org/abstracts/search?q=diluted%20magnetic%20semiconductors" title=" diluted magnetic semiconductors"> diluted magnetic semiconductors</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20properties" title=" magnetic properties"> magnetic properties</a>, <a href="https://publications.waset.org/abstracts/search?q=silicon%20carbide" title=" silicon carbide"> silicon carbide</a> </p> <a href="https://publications.waset.org/abstracts/34017/first-principle-calculation-of-the-magnetic-properties-of-mn-doped-6h-sic" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34017.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">291</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1750</span> Investigation of Active Modified Atmosphere and Nanoparticle Packaging on Quality of Tomatoes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Ghasemi-Varnamkhasti">M. Ghasemi-Varnamkhasti</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20H.%20Yoosefian"> S. H. Yoosefian</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Mohammad-Razdari"> A. Mohammad-Razdari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study investigated the effects of Ag nanoparticle polyethylene film and active modified atmosphere on the postharvest quality of tomatoes stored at 6 ºC. The atmosphere composition used in the packaging was 7% O<sub>2</sub> + 7% CO<sub>2 </sub>+ 86% N<sub>2</sub>, and synthetic air (control). The variables measured were weight loss, firmness, color and respiration rate over 21 days. The results showed that the combination of Ag nanoparticle polyethylene film and modified atmosphere could extend the shelf life of tomatoes to 21 days and could influence the postharvest quality of tomatoes. Also, existence of Ag nanoparticles caused preventing from increasing weight loss, a*, b*, Chroma, Hue angle and reducing firmness and L*. As well as, tomatoes at Ag nanoparticle polyethylene films had lower respiration rate than Polyethylene and paper bags to 13.27% and 23.50%, respectively. The combination of Ag nanoparticle polyethylene film and active modified atmosphere was effective with regard to delaying maturity during the storage period, and preserving the quality of tomatoes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ag%20nanoparticles" title="ag nanoparticles">ag nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=modified%20atmosphere" title=" modified atmosphere"> modified atmosphere</a>, <a href="https://publications.waset.org/abstracts/search?q=polyethylene%20film" title=" polyethylene film"> polyethylene film</a>, <a href="https://publications.waset.org/abstracts/search?q=tomato" title=" tomato"> tomato</a> </p> <a href="https://publications.waset.org/abstracts/54383/investigation-of-active-modified-atmosphere-and-nanoparticle-packaging-on-quality-of-tomatoes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">276</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">‹</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticle&page=5">5</a></li> <li class="page-item"><a class="page-link" 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