Production of Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus through the Biocatalysis of Vegetable Oils

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class="card-body"><strong>Paper Count:</strong> 87407</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Production of Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus through the Biocatalysis of Vegetable Oils</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hak-Ryul%20Kim">Hak-Ryul Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyung-Geun%20Lee"> Hyung-Geun Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Qi%20Long"> Qi Long</a>, <a href="https://publications.waset.org/abstracts/search?q=Ching%20Hou"> Ching Hou</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Structural modification of natural lipids via chemical reaction or microbial bioconversion can change their properties or even create novel functionalities. Enzymatic oxidation of lipids leading to formation of oxylipin is one of those modifications. Hydroxy fatty acids, one of those oxylipins have gained important attentions because of their structural and functional properties compared with other non-hydroxy fatty acids. Recently 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) was produced with high yield from lipid-containing oleic acid by microbial conversion, and the further study confirmed that DOD contained strong antimicrobial activities against a broad range of microorganisms. In this study, we tried to modify DOD molecules by the enzymatic or physical reaction to create new functionality or to enhance the antimicrobial activity of DOD. After modification of DOD molecules by different ways, we confirmed that the antimicrobial activity of DOD was highly enhanced and presented strong antimicrobial activities against multidrug-resistant Staphylococcus aureus, suggesting that DOD and its derivatives can be used as efficient antimicrobial agents for medical and industrial applications. <iframe src="https://publications.waset.org/abstracts/75239.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biocatalysis" title="biocatalysis">biocatalysis</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20agent" title=" antimicrobial agent"> antimicrobial agent</a>, <a href="https://publications.waset.org/abstracts/search?q=multidrug-resistant%20bacteria" title=" multidrug-resistant bacteria"> multidrug-resistant bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=vegetable%20oil" title=" vegetable oil"> vegetable oil</a> </p> <a href="https://publications.waset.org/abstracts/75239/production-of-antimicrobial-agents-against-multidrug-resistant-staphylococcus-aureus-through-the-biocatalysis-of-vegetable-oils" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75239.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">205</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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Production of Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus through the Biocatalysis of Vegetable Oils