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<!doctype html> <html lang="ja"> <head> <title>Role of NRG1 Coalescence for Treatment of Lung Cancer in Pat | 92398</title> <meta name="keywords" content="Muhammad Imran Qadir, Hooria Ghias*, Syed Shahbal, "/> <meta name="description" content="Gene-targeted treatments for lung cancer have significantly increased survival rates when compared to conventional chemotherapy. In both Europe and the Uni..92398"/> <meta name="citation_publisher" content="ロングダム出版SL" /> <meta name="citation_journal_title" content="遺伝子工学の進歩"> <meta name="citation_title" content="Role of NRG1 Coalescence for Treatment of Lung Cancer in Patients"> <meta name="citation_author" content="Muhammad Imran Qadir" /> <meta name="citation_author" content="Hooria Ghias" /> <meta name="citation_author" content="Syed Shahbal" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="12"> <meta name="citation_issue" content="1"> <meta name="citation_abstract" content="Gene-targeted treatments for lung cancer have significantly increased survival rates when compared to conventional chemotherapy. In both Europe and the United States, researchers are looking into the therapeutic potential of a gene fusion called Neuregulin 1 (NRG1). The purpose of this review is to highlight the importance of this novel fusion in the treatment of lung cancer and the most recent achievements in this field. In a broad spectrum of cancers, oncogenic gene fusions originate from structural DNA rearrangements that promote uncontrolled cell proliferation. The genes of cross-breeds As a result, drugs to inhibit cell growth and proliferation have been created. Lung cancer therapy is increasingly focusing on oncogene fusions such as ALK, RET, NTRK, and ROS1, among others. Many diseases have been linked to NRG gene fusions, which have been linked to a variety of solid tumours (including kidney and pancreatic cancer, breast and colorectal cancer, and lung cancer). As has been the case for decades, oncology treatment will continue to evolve, moving from a focus on the disease's genesis to a more genetically-based approach. In addition to improving survival rates, the increased availability of these drugs has sparked a renewed interest in finding new therapies. Keywords: Multiplex technique; NRG gene; Molecular indicators; Oncogenic gene fusions"> <meta name="citation_abstract_html_url" content="https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html"> <meta name="format-detection" content="telephone=no"> <meta http-equiv="Content-Language" content="ja"> <meta name="google-site-verification" content="NomPTP94YozsgvD3NEFpNqUfY88e0TU0L64zNzZTpd0" /> <meta itemprop="name" content="longdom" /> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="ROBOTS" content="INDEX,FOLLOW"> <meta name="googlebot" content="INDEX,FOLLOW"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <link rel="canonical" href="https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html"> <link rel="alternate" 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class="col-12 col-sm-9"> <h2 class="heading-1">概要</h2> <h3 class="">Role of NRG1 Coalescence for Treatment of Lung Cancer in Patients</h3> <p> <i class="fas fa-user"></i> Muhammad Imran Qadir, Hooria Ghias*, Syed Shahbal </p> <p>Gene-targeted treatments for lung cancer have significantly increased survival rates when compared to conventional chemotherapy. In both Europe and the United States, researchers are looking into the therapeutic potential of a gene fusion called Neuregulin 1 (NRG1). The purpose of this review is to highlight the importance of this novel fusion in the treatment of lung cancer and the most recent achievements in this field. In a broad spectrum of cancers, oncogenic gene fusions originate from structural DNA rearrangements that promote uncontrolled cell proliferation. The genes of cross-breeds As a result, drugs to inhibit cell growth and proliferation have been created. Lung cancer therapy is increasingly focusing on oncogene fusions such as ALK, RET, NTRK, and ROS1, among others. Many diseases have been linked to NRG gene fusions, which have been linked to a variety of solid tumours (including kidney and pancreatic cancer, breast and colorectal cancer, and lung cancer). As has been the case for decades, oncology treatment will continue to evolve, moving from a focus on the disease's genesis to a more genetically-based approach. In addition to improving survival rates, the increased availability of these drugs has sparked a renewed interest in finding new therapies.</p> <p><strong>Keywords</strong>: Multiplex technique; NRG gene; Molecular indicators; Oncogenic gene fusions</p> <div class="alert alert-info text-left"><b>免責事項:</b> この要約は人工知能ツールを使用して翻訳されたものであり、まだレビューまたは検証されていません。</div> <div class="nav social-icons"> <a class="nav-link w-auto">この記事をシェアする</a> <a title="ここをクリック" target="_blank" href="https://www.facebook.com/sharer.php?u=https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://twitter.com/share?url=https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://plus.google.com/share?url=https://japanese.longdom.org/abstract/role-of-nrg1-coalescence-for-treatment-of-lung-cancer-in-patients-92398.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">コンテンツリンク</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://japanese.longdom.org/privacy-policy.html" title="ここをクリック">プライバシーポリシー</a></li> <li><a class="" href="https://japanese.longdom.org/terms-conditions.html" title="ここをクリック">利用規約</a></li> <li><a class="" href="https://japanese.longdom.org/authors-reviewers-editors.html" title="ここをクリック">著者、査読者、編集者</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">ロングダムに連絡する</h4> <p><strong>ロングダムグループ SA</strong><br /> ロジェ・ヴァンデンドリッシュ通り、<br /> 18、1150 ブリュッセル、ベルギー<br /> 電話番号: +442038085340<br /> <strong>メール:</strong> <a class="white" href="mailto:info@longdom.org" title="ここをクリック">info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">接続</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="ここをクリック" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="ここをクリック" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="ここをクリック" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="ここをクリック" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>著作権 © 2024 <a href="https://japanese.longdom.org/" title="ここをクリック" class="white">ロングダム出版SL</a>.</p> </div> </div> </div> </footer>  <a href="#0" class="cd-top js-cd-top">Top</a>   <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script>  <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? 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