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Linda B. Buck

<html> <head> <title>Linda B. 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Buck</b></font><p><img src="linda-buck.jpg" height=286 width=240 align=right hspace=10 vspace=10 alt="Linda B. Buck"><b>Born:</b> <a href="/lists/546/000106228/" class=proflink>29-Jan</a>-<a href="/lists/946/000105631/" class=proflink>1947</a><br><b>Birthplace:</b> <a href="/geo/710/000069503/" class=proflink>Seattle, WA</a><br><p><b>Gender:</b> Female<br><b>Race or Ethnicity:</b> White<br><b>Sexual orientation:</b> Straight<br><b>Occupation:</b> <a href="/lists/642/000096354/" class=proflink>Biologist</a><p><b>Nationality:</b> United States<br><b>Executive summary:</b> Odorant receptors and olfactory organization<p>American neurobiologist Linda B. Buck has studied how odors are perceived and identified. Her work has shown that the mammalian olfactory system senses a huge variety of structurally diverse chemicals in the external environment, mostly as odors, although certain chemical compounds such as pheromones and predator odors are not consciously smelled but more basically stimulate hormonal changes or instinctive behaviors.<p> With her colleague, <a href="/people/711/000136303/">Richard Axel</a>, she cloned olfactory receptors in 1991, proving that smell-detectors are G protein-coupled receptors. In 1993 and 1994 she detailed the organization of odor receptor neurons in the nose, and in 2004 she and Axel shared the Nobel Prize for Medicine or Physiology for her research into the molecular mechanics of the sense of smell. She continues her works at the Fred Hutchinson Cancer Research Center in Seattle.<p><b>Father:</b> (electrical engineer)<br><b>Mother:</b> (homemaker)<br><b>Sister:</b> (2 sisters)<br><p>&nbsp; &nbsp; High School: Roosevelt High School, Seattle, WA (1965)<br>&nbsp; &nbsp; University: <a href="/edu/903/000104591/">BS Psychology, University of Washington (1975)</a><br>&nbsp; &nbsp; University: <a href="/edu/903/000104591/">BS Microbiology, University of Washington (1975)</a><br>&nbsp; &nbsp; University: <a href="/edu/365/000082119/">PhD Immunology, University of Texas at Dallas (1980)</a><br>&nbsp; &nbsp; Fellow: <a href="/edu/477/000068273/">Postdoctorate, Columbia University (1980-84)</a><br>&nbsp; &nbsp; Teacher: <a href="/edu/403/000127022/">Neurobiology, Harvard Medical School (1991-2001)</a><br>&nbsp; &nbsp; Professor: <a href="/edu/403/000127022/">Neurobiology, Harvard Medical School (2001-02)</a><br>&nbsp; &nbsp; Teacher: <a href="/edu/903/000104591/">Physiology and Biophysics, University of Washington (2002-)</a><br><p>&nbsp; &nbsp; <u>Takasago Award</u> 1992<br> &nbsp; &nbsp; <u>Lewis S. Rosenstiel Award</u> 1997<br> &nbsp; &nbsp; <u>Gairdner Foundation International Award</u> 2003<br> &nbsp; &nbsp; <a href="/honors/214/000068010/">Nobel Prize for Medicine</a> 2004 (with <a href="/people/711/000136303/">Richard Axel</a>)<br>&nbsp; &nbsp; <a href="/org/811/000055646/">American Academy of Arts and Sciences</a> 2008<br>&nbsp; &nbsp; <a href="/org/766/000051613/">American Association for the Advancement of Science</a> 2002<br>&nbsp; &nbsp; <u>Fred Hutchinson Cancer Research Center (2002-)</u> <br> &nbsp; &nbsp; <a href="/org/136/000124761/">Howard Hughes Medical Institute</a> Investigator (2001-)<br>&nbsp; &nbsp; <a href="/org/136/000124761/">Howard Hughes Medical Institute</a> Associate Investigator (1997-2000)<br>&nbsp; &nbsp; <a href="/org/136/000124761/">Howard Hughes Medical Institute</a> Ass't Investigator (1994-97)<br>&nbsp; &nbsp; <a href="/org/136/000124761/">Howard Hughes Medical Institute</a> Associate (1984-94)<br>&nbsp; &nbsp; <a href="/org/630/000117279/">Alfred P. Sloan Foundation</a> Fellowship, 1992<br>&nbsp; &nbsp; <a href="/org/469/000164974/">Institute of Medicine</a> 2006<br>&nbsp; &nbsp; <a href="/org/692/000054530/">National Academy of Sciences</a> 2003<br>&nbsp; &nbsp; <a href="/lists/936/000043807/">Irish Ancestry</a> Paternal<br> &nbsp; &nbsp; <a href="/lists/528/000044396/">Swedish Ancestry</a> Maternal<br> <p> <br> <p> <table> <tr> <td align=right valign=middle style="padding-right: 5px;"><span style="font-family: Georgia, serif; font-size: 22px; font-style: italic; color: #ff3333;">New!</span><br> <a href="http://mapper.nndb.com/" class="fotmlink" style="font-family: Tahoma, sans-serif; font-size: 10px; font-weight: bold; text-decoration: none; color: #dd0000;">NNDB MAPPER</a></td> <td valign=middle align=right style="border-left: 1px solid #bbb; padding-left: 5px;">Create a map starting with</td> <td valign=middle align=right><a href="http://mapper.nndb.com/start/?id=125354"><img src="/woman.gif" border=0 style="padding: 2px;"></a></td> <td align=left valign=middle> <a href="http://mapper.nndb.com/start/?id=125354">Linda B. 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